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18 results on '"Neumann, Christopher S."'

1. Supplementary Tables and Figures from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

Author

Neumann, Christopher S., primary, Olivas, Kathleen C., primary, Anderson, Martha E., primary, Cochran, Julia H., primary, Jin, Steven, primary, Li, Fu, primary, Loftus, Luke V., primary, Meyer, David W., primary, Neale, Jason, primary, Nix, Jay C., primary, Pittman, Paul G., primary, Simmons, Jessica K., primary, Ulrich, Michelle L., primary, Waight, Andrew B., primary, Wong, Abbie, primary, Zaval, Margo C., primary, Zeng, Weiping, primary, Lyon, Robert P., primary, and Senter, Peter D., primary

Published
2023
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2. Supplementary Methods from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

Author

Neumann, Christopher S., primary, Olivas, Kathleen C., primary, Anderson, Martha E., primary, Cochran, Julia H., primary, Jin, Steven, primary, Li, Fu, primary, Loftus, Luke V., primary, Meyer, David W., primary, Neale, Jason, primary, Nix, Jay C., primary, Pittman, Paul G., primary, Simmons, Jessica K., primary, Ulrich, Michelle L., primary, Waight, Andrew B., primary, Wong, Abbie, primary, Zaval, Margo C., primary, Zeng, Weiping, primary, Lyon, Robert P., primary, and Senter, Peter D., primary

Published
2023
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3. Data from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

Author

Neumann, Christopher S., primary, Olivas, Kathleen C., primary, Anderson, Martha E., primary, Cochran, Julia H., primary, Jin, Steven, primary, Li, Fu, primary, Loftus, Luke V., primary, Meyer, David W., primary, Neale, Jason, primary, Nix, Jay C., primary, Pittman, Paul G., primary, Simmons, Jessica K., primary, Ulrich, Michelle L., primary, Waight, Andrew B., primary, Wong, Abbie, primary, Zaval, Margo C., primary, Zeng, Weiping, primary, Lyon, Robert P., primary, and Senter, Peter D., primary

Published
2023
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7. Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

Author

Neumann, Christopher S., primary, Olivas, Kathleen C., additional, Anderson, Martha E., additional, Cochran, Julia H., additional, Jin, Steven, additional, Li, Fu, additional, Loftus, Luke V., additional, Meyer, David W., additional, Neale, Jason, additional, Nix, Jay C., additional, Pittman, Paul G., additional, Simmons, Jessica K., additional, Ulrich, Michelle L., additional, Waight, Andrew B., additional, Wong, Abbie, additional, Zaval, Margo C., additional, Zeng, Weiping, additional, Lyon, Robert P., additional, and Senter, Peter D., additional

Published
2018
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8. Abstract 930: Targeted delivery of cytotoxic NAMPT inhibitors using antibody-drug conjugates

Author

Neumann, Christopher S., primary, Olivas, Kathleen C., additional, Waight, Andrew B., additional, Meyer, David, additional, Loftus, Luke V., additional, Zaval, Margo, additional, Anderson, Martha E., additional, Jin, Steven, additional, Cochran, Julia H., additional, Simmons, Jessica K., additional, Pittman, Paul G., additional, Lyon, Robert P., additional, and Senter, Peter D., additional

Published
2018
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9. Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an [Fe.sup.II]-dependent halogenase and a cyclopropane-forming flavoprotein

Author

Neumann, Christopher S. and Walsh, Christopher T.

Subjects
Actinomycetes -- Physiological aspects, Actinomycetes -- Genetic aspects, Cyclopropane compounds -- Chemical properties, Halogenation -- Analysis, Iron -- Chemical properties, Peptides -- Chemical properties, Chemistry
Abstract

Halogenase-directed probes were used to clone the gene cluster responsible for the biosynthesis of a series of hexadepsipeptides, kutnerides, isolated from the soil actinomycete kutzneria. These molecules contain a number of unusual monomers.

Published
2008

10. A library of spirooxindoles based on a stereoselective three-component coupling reaction

Author

Lo, Michael M.-C., Neumann, Christopher S., Nagayama, Satoshi, Peristein, Ethan O., and Schreiber, Stuart L.

Subjects
Molecular structure -- Research, Biochemical genetics -- Structure, Chemistry
Abstract

The split-pool synthesis of more than 3000 spirooxindoles on high capacity macrobeads is reported. A high-throughput chemical genetic modifier screen performed using stock solutions of the resultant products to demonstrate the utility of the discovery process.

Published
2004

18. Biosynthesis of (—)-(1 S,2R-AIIocoronamic Acyl Thioester by an Fe"-Dependent Halogenase and a Cyclopropane-Forming Flavoprotein.

Author

Neumann, Christopher S. and Walsh, Christopher T.

Subjects
*PROTEIN synthesis, *BIOSYNTHESIS, *CYCLOPROPANE, *FLAVOPROTEINS, *ESCHERICHIA coli, *BACTERIAL genetics, *MOLECULAR cloning, *AMINO acids
Abstract

The article presents a study which examines the biosynthesis of Allocoronamic Acyl Thioster by an Fe''-dependent Halogenase and a Cyclopropane-Forming Flavoprotein. It notes that the four-protein cassette KtzABCD was used as flavoprotein to test if it can yield cyclopropyl-containing amino acid. Moreover, it mentions that the KtzABCD was cloned in Escherichia coli expression. It also concludes that the KtzABCD proteins synthesis rendered alloCMA as product of the enzymes.

Published
2008
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