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There have been many studies and reports on carcinoma of the lip since the publication of the paper of Broders1 in 1920 on the grading of tumors. However, on reviewing the more recent literature, one finds little accord among surgeons, radiologists and dermatologists on the methods and results of treatment. This may be because both operation and irradiation are satisfactory methods of treatment provided sufficient skill and knowledge are used. The purpose of this paper is to report a rather large series of cases followed beyond the five year period, in which the tumors were treated by surgical operation, and to emphasize the necessity for routine microscopic examination. A comparison is made with the other accepted forms of treatment, that is, irradiation and cauterization. It is difficult to make a true comparison of results, however, because of differences in duration, severity and size of the lesions reported in the

Wounds involving the skin and the subcutaneous tissues are readily attacked by pyogenic organisms. In the majority of cases the superficial nature of the wound, which permits adequate drainage, results in satisfactory healing. A certain percentage of such wounds, however, become chronically infected because of some complicating factor, such as diabetes, a circulatory disturbance or trauma resulting in devitalization of the surrounding tissues. The protracted course of infected wounds in diabetic patients despite adequate diabetic therapy, the tenacious infections in wounds following the excision of carbuncles and the chronic sloughing wounds following subcutaneous trauma often discourage both patients and surgeons. The use of compresses wet with hot saline solution is beneficial in such cases, but the method is laborious and sometimes fails to clean up the infection. The present study was undertaken to determine whether a simpler and more effective method of treatment could be found, which would result in