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5. 1064nm Nd:YAG laser promotes chondrocytes regeneration and cartilage reshaping by upregulating local estrogen levels.

Author

Zhu, Yingjie, Zhou, Xueqing, Peng, Xieling, Li, Hantao, Wang, Hongshun, Guo, Ziwei, Xiong, Yang, Xu, Jiaqi, Ni, Xiangrong, and Qi, Xiangdong

Abstract

Cartilage is frequently used as a scaffolds for repairing and reconstructing body surface organs. However, after successful plastic surgery, transplanted cartilage scaffolds often exhibit deformation and absorption over time. To enhance the shaping stability of cartilage scaffolds and improve patients' satisfaction after reconstructions, we employed the ear folding models in New Zealand rabbits to confirm whether the 1064nm neodymium‐doped yttrium aluminum garnet (Nd:YAG) laser could promote cartilage reshaping. There was an increase in collagen and aromatase (Cyp19) expression within the ear cartilage after laser treatment. Moreover, we have found that the Cyp19 inhibitor can inhibit the laser's effect on cartilage shaping and reduce collagen and Cyp19 expression. The overall findings suggest that treatment with 1064nm Nd:YAG laser irradiation can enhance estrogen levels in local cartilage tissues by upregulating Cyp19 expression in chondrocytes through photobiomodulation, thereby promoting the proliferation and collagen secretion of chondrocytes to improve cartilage reshaping and stability. [ABSTRACT FROM AUTHOR]

Published
2024
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6. CCDC50 promotes tumor growth through regulation of lysosome homeostasis

Author

Jia, Penghui, primary, Tian, Tian, additional, Li, Zibo, additional, Wang, Yicheng, additional, Lin, Yuxin, additional, Zeng, Weijie, additional, Ye, Yu, additional, He, Miao, additional, Ni, Xiangrong, additional, Pan, Ji'an, additional, Dong, Xiaonan, additional, Huang, Jian, additional, Li, Chun‐mei, additional, Guo, Deyin, additional, and Hou, Panpan, additional

Published
2023
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8. Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas

Author

Guo, Chengcheng, primary, Yang, Qunying, additional, Xu, Pengfei, additional, Deng, Meiling, additional, Jiang, Taipeng, additional, Cai, Linbo, additional, Li, Jibin, additional, Sai, Ke, additional, Xi, Shaoyan, additional, Ouyang, Hui, additional, Liu, Mingfa, additional, Li, Xianming, additional, Li, Zihuang, additional, Ni, Xiangrong, additional, Cao, Xi, additional, Li, Cong, additional, Wu, Shaoxiong, additional, Du, Xiaojing, additional, Su, Jun, additional, Xue, Xiaoying, additional, Wang, Yiming, additional, Li, Gang, additional, Qin, Zhiyong, additional, Yang, Hui, additional, Zhou, Tao, additional, Liu, Jinquan, additional, Hu, Xuefeng, additional, Wang, Jian, additional, Jiang, Xiaobing, additional, Lin, Fuhua, additional, Zhang, Xiangheng, additional, Ke, Chao, additional, Lv, Xiaofei, additional, Lv, Yanchun, additional, Hu, Wanming, additional, Zeng, Jing, additional, Chen, Zhenghe, additional, Zhong, Sheng, additional, Wang, Hairong, additional, Chen, Yinsheng, additional, Zhang, Ji, additional, Li, Depei, additional, Mou, Yonggao, additional, and Chen, Zhongping, additional

Published
2023
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9. Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN -null glioblastoma

Author

Ni, Xiangrong, primary, Wu, Weichi, additional, Sun, Xiaoqiang, additional, Ma, Junxiao, additional, Yu, Zhihui, additional, He, Xinwei, additional, Cheng, Jinyu, additional, Xu, Pengfei, additional, Liu, Haoxian, additional, Shang, Tengze, additional, Xi, Shaoyan, additional, Wang, Jing, additional, Zhang, Ji, additional, and Chen, Zhongping, additional

Published
2022
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