895 results on '"Nickel, B."'
Search Results
2. Search for $hep$ solar neutrinos and the diffuse supernova neutrino background using all three phases of the Sudbury Neutrino Observatory
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Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Blucher, E., Bonventre, R., Boudjemline, K., Boulay, M. G., Cai, B., Callaghan, E. J., Caravaca, J., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Descamps, F. B., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Dunford, M., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gilje, K., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kraus, C., Krauss, C. B., Krüger, A., Kutter, T., Kyba, C. C. M., Labe, K., Land, B. J., Lange, R., LaTorre, A., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., Mastbaum, A., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tešić, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Winchester, T., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment ,Nuclear Experiment - Abstract
A search has been performed for neutrinos from two sources, the $hep$ reaction in the solar $pp$ fusion chain and the $\nu_e$ component of the diffuse supernova neutrino background (DSNB), using the full dataset of the Sudbury Neutrino Observatory with a total exposure of 2.47 kton-years after fiducialization. The $hep$ search is performed using both a single-bin counting analysis and a likelihood fit. We find a best-fit flux that is compatible with solar model predictions while remaining consistent with zero flux, and set a one-sided upper limit of $\Phi_{hep} < 30\times10^{3}~\mathrm{cm}^{-2}~\mathrm{s}^{-1}$ [90% credible interval (CI)]. No events are observed in the DSNB search region, and we set an improved upper bound on the $\nu_e$ component of the DSNB flux of $\Phi^\mathrm{DSNB}_{\nu_e} < 19~\textrm{cm}^{-2}~\textrm{s}^{-1}$ (90% CI) in the energy range $22.9 < E_\nu < 36.9$~MeV., Comment: 11 pages, 6 figures
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- 2020
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3. Cosmogenic Neutron Production at the Sudbury Neutrino Observatory
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Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Bonventre, R., Boudjemline, K., Boulay, M. G., Cai, B., Callaghan, E. J., Caravaca, J., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Curley, R., Dai, X., Deng, H., Descamps, F. B., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Dunford, M., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gilje, K., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Kéfélian, C., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kr\u, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Land, B. J., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., Mastbaum, A., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Teš, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Winchester, T., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment ,Nuclear Experiment - Abstract
Neutrons produced in nuclear interactions initiated by cosmic-ray muons present an irreducible background to many rare-event searches, even in detectors located deep underground. Models for the production of these neutrons have been tested against previous experimental data, but the extrapolation to deeper sites is not well understood. Here we report results from an analysis of cosmogenically produced neutrons at the Sudbury Neutrino Observatory. A specific set of observables are presented, which can be used to benchmark the validity of GEANT4 physics models. In addition, the cosmogenic neutron yield, in units of $10^{-4}\;\text{cm}^{2}/\left(\text{g}\cdot\mu\right)$, is measured to be $7.28 \pm 0.09\;\text{stat.} ^{+1.59}_{-1.12}\;\text{syst.}$ in pure heavy water and $7.30 \pm 0.07\;\text{stat.} ^{+1.40}_{-1.02}\;\text{syst.}$ in NaCl-loaded heavy water. These results provide unique insights into this potential background source for experiments at SNOLAB.
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- 2019
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4. Measurement of neutron production in atmospheric neutrino interactions at the Sudbury Neutrino Observatory
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SNO Collaboration, Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Bonventre, R., Boudjemline, K., Boulay, M. G., Cai, B., Callaghan, E. J., Caravaca, J., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Descamps, F. B., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Dunford, M., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gilje, K., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kruger, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Land, B. J., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., Mastbaum, A., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Sinclair, D., Singh, J., Skensved, P., Smiley, M., Sonley, T. J., Stonehill, L. C., Tesic, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Winchester, T., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment - Abstract
Neutron production in GeV-scale neutrino interactions is a poorly studied process. We have measured the neutron multiplicities in atmospheric neutrino interactions in the Sudbury Neutrino Observatory experiment and compared them to the prediction of a Monte Carlo simulation using GENIE and a minimally modified version of GEANT4. We analyzed 837 days of exposure corresponding to Phase I, using pure heavy water, and Phase II, using a mixture of Cl in heavy water. Neutrons produced in atmospheric neutrino interactions were identified with an efficiency of $15.3\%$ and $44.3\%$, for Phase I and II respectively. The neutron production is measured as a function of the visible energy of the neutrino interaction and, for charged current quasi-elastic interaction candidates, also as a function of the neutrino energy. This study is also performed classifying the complete sample into two pairs of event categories: charged current quasi-elastic and non charged current quasi-elastic, and $\nu_{\mu}$ and $\nu_e$. Results show good overall agreement between data and Monte Carlo for both phases, with some small tension with a statistical significance below $2\sigma$ for some intermediate energies.
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- 2019
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5. Constraints on Neutrino Lifetime from the Sudbury Neutrino Observatory
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SNO Collaboration, Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Bonventre, R., Boudjemline, K., Boulay, M. G., Cai, B., Callaghan, E. J., Caravaca, J., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Descamps, F. B., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Dunford, M., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gilje, K., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Kéfélian, C., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Krüger, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Land, B. J., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., Mastbaum, A., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tešić, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Winchester, T., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment ,Nuclear Experiment - Abstract
The long baseline between the Earth and the Sun makes solar neutrinos an excellent test beam for exploring possible neutrino decay. The signature of such decay would be an energy-dependent distortion of the traditional survival probability which can be fit for using well-developed and high precision analysis methods. Here a model including neutrino decay is fit to all three phases of $^8$B solar neutrino data taken by the Sudbury Neutrino Observatory. This fit constrains the lifetime of neutrino mass state $\nu_2$ to be ${>8.08\times10^{-5}}$ s/eV at $90\%$ confidence. An analysis combining this SNO result with those from other solar neutrino experiments results in a combined limit for the lifetime of mass state $\nu_2$ of ${>1.04\times10^{-3}}$ s/eV at $99\%$ confidence.
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- 2018
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6. Tests of Lorentz invariance at the Sudbury Neutrino Observatory
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SNO Collaboration, Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Blucher, E., Bonventre, R., Boudjemline, K., Boulay, M. G., Cai, B., Callaghan, E. J., Caravaca, J., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Descamps, F. B., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Dunford, M., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Gilje, K., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Kefelian, C., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kruger, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Labe, K., Land, B. J., Lange, R., LaTorre, A., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., Mastbaum, A., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tesic, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Winchester, T., Wilson, J. R., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment ,Nuclear Experiment - Abstract
Experimental tests of Lorentz symmetry in systems of all types are critical for ensuring that the basic assumptions of physics are well-founded. Data from all phases of the Sudbury Neutrino Observatory, a kiloton-scale heavy water Cherenkov detector, are analyzed for possible violations of Lorentz symmetry in the neutrino sector. Such violations would appear as one of eight possible signal types in the detector: six seasonal variations in the solar electron neutrino survival probability differing in energy and time dependence, and two shape changes to the oscillated solar neutrino energy spectrum. No evidence for such signals is observed, and limits on the size of such effects are established in the framework of the Standard Model Extension, including 40 limits on perviously unconstrained operators and improved limits on 15 additional operators. This makes limits on all minimal, Dirac-type Lorentz violating operators in the neutrino sector available for the first time.
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- 2018
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7. The search for neutron-antineutron oscillations at the Sudbury Neutrino Observatory
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SNO Collaboration, Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Boudjemline, K., Boulay, M. G., Cai, B., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Detwiler, J. A., Doe, P. J., Doucas, G., Drouin, P. -L., Duncan, F. A., Dunford, M., Earle, E. D., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kruger, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R. D., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Okada, C. E., Ollerhead, R. W., OrebiGann, G. D., Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Simpson, J. J., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tesic, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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High Energy Physics - Experiment ,Nuclear Experiment ,Physics - Instrumentation and Detectors - Abstract
Tests on $B-L$ symmetry breaking models are important probes to search for new physics. One proposed model with $\Delta(B-L)=2$ involves the oscillations of a neutron to an antineutron. In this paper a new limit on this process is derived for the data acquired from all three operational phases of the Sudbury Neutrino Observatory experiment. The search was concentrated in oscillations occurring within the deuteron, and 23 events are observed against a background expectation of 30.5 events. These translate to a lower limit on the nuclear lifetime of $1.48\times 10^{31}$ years at 90% confidence level (CL) when no restriction is placed on the signal likelihood space (unbounded). Alternatively, a lower limit on the nuclear lifetime was found to be $1.18\times 10^{31}$ years at 90% CL when the signal was forced into a positive likelihood space (bounded). Values for the free oscillation time derived from various models are also provided in this article. This is the first search for neutron-antineutron oscillation with the deuteron as a target., Comment: 14 pages, 8 figures
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- 2017
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8. Participant factors associated with psychosocial impacts of lung cancer screening: A systematic review
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McFadden, K, Nickel, B, Rankin, NM, Li, T, Jennett, CJ, Sharman, A, Quaife, SL, Houssami, N, Dodd, RH, McFadden, K, Nickel, B, Rankin, NM, Li, T, Jennett, CJ, Sharman, A, Quaife, SL, Houssami, N, and Dodd, RH
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BACKGROUND: Psychosocial impacts of lung cancer screening (LCS) can cause both harm to individuals and serve as barriers to screening participation and adherence. Early data suggest that the psychosocial impacts of LCS are moderated by certain factors (e.g. sociodemographic characteristics and beliefs), but evidence synthesis is lacking. This systematic review aimed to understand individual-level risk factors for psychosocial burden during LCS as a precursor to developing strategies to identify and support participants, and improve LCS engagement. METHODS: Four databases were searched for full-text articles published in English reporting any association between participant factors and psychosocial outcomes experienced during LCS. Study quality was assessed by two independent investigators; findings were synthesised narratively. The review was pre-registered with PROSPERO and adhered to PRISMA guidelines. RESULTS: Thirty-five articles were included; most (33/35) studies were assessed at high or moderate risk of bias. Study designs were pre-post (n = 13), cross-sectional (n = 13), qualitative (n = 8) and mixed-methods (n = 1) and conducted primarily in the United States (n = 17). Psychological burden in LCS varied, and was often associated with younger age, female gender, current smoking status or increased smoking history, lower education, lower socio-economic group, not being married or co-habiting and experience with cancer. However, results were mixed, and non-significant associations were also reported across all factors. Beliefs (e.g. fatalism, stigma and expectation of LDCT results) and comorbid psychological burden were also linked to psychosocial outcomes, but evidence was sparse. Associations between risk perception, other participant factors and other psychosocial outcomes was inconclusive, likely reflecting individual biases in risk conceptualisation. CONCLUSION(S): Several participant factors are consistently reported to be associated with psychosocial im
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- 2024
9. The impact of delayed diagnosis and treatment due to COVID-19 on Australian thyroid cancer patients: a qualitative interview study.
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D'souza, B, Glover, A, Bavor, C, Brown, B, Dodd, RH, Lee, JC, Millar, J, Miller, JA, Zalcberg, JR, Serpell, J, Ioannou, LJ, Nickel, B, D'souza, B, Glover, A, Bavor, C, Brown, B, Dodd, RH, Lee, JC, Millar, J, Miller, JA, Zalcberg, JR, Serpell, J, Ioannou, LJ, and Nickel, B
- Abstract
OBJECTIVES: The study aims to investigate the perceptions of patients with thyroid cancer on the potential impact of diagnosis and treatment delays during the COVID-19 pandemic. DESIGN: This study involved qualitative semi-structured telephone interviews. The interviews were transcribed verbatim, analysed using the thematic framework analysis method and reported using the Consolidated Criteria for Reporting Qualitative Research. SETTING: Participants in the study were treated and/or managed at hospital sites across New South Wales and Victoria, Australia. PARTICIPANTS: 17 patients with thyroid cancer were interviewed and included in the analysis (14 females and 3 males). RESULTS: The delays experienced by patients ranged from <3 months to >12 months. The patients reported about delays to diagnostic tests, delays to surgery and radioactive iodine treatment, perceived disease progression and, for some, the financial burden of choosing to go through private treatment to minimise the delay. Most patients also reported not wanting to experience delays any longer than they did, due to unease and anxiety. CONCLUSIONS: This study highlights an increased psychological burden in patients with thyroid cancer who experienced delayed diagnosis and/or treatment during COVID-19. The impacts experienced by patients during this time may be similar in the case of other unexpected delays and highlight the need for regular clinical review during delays to diagnosis or treatment.
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- 2024
10. Seltener histopathologischer Befund bei Skrotalhernie
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Graf, C., Nickel, B., and Kraft, B.
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- 2020
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11. A Search for Astrophysical Burst Signals at the Sudbury Neutrino Observatory
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Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Boudjemline, K., Boulay, M. G., Cai, B., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Detwiler, J. A., DiMarco, M., Diamond, M. D., Doe, P. J., Doucas, G., Drouin, P. -L., Duncan, F. A., Dunford, M., Earle, E. D., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kraus, C., Krauss, C. B., Krueger, A., Kutter, T., Kyba, C. C. M., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Levine, I., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Simpson, J. J., Sinclair, D., Skensved, P., Sonley, T. J., Stonehill, L. C., Tesic, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wark, D. L., Watson, P. J. S., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Wouters, J. M., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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Astrophysics - Solar and Stellar Astrophysics ,Nuclear Experiment - Abstract
The Sudbury Neutrino Observatory (SNO) has confirmed the standard solar model and neutrino oscillations through the observation of neutrinos from the solar core. In this paper we present a search for neutrinos associated with sources other than the solar core, such as gamma-ray bursters and solar flares. We present a new method for looking for temporal coincidences between neutrino events and astrophysical bursts of widely varying intensity. No correlations were found between neutrinos detected in SNO and such astrophysical sources.
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- 2013
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12. Combined Analysis of all Three Phases of Solar Neutrino Data from the Sudbury Neutrino Observatory
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SNO Collaboration, Aharmim, B., Ahmed, S. N., Anthony, A. E., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Boudjemline, K., Boulay, M. G., Cai, B., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Dai, X., Deng, H., Detwiler, J. A., DiMarco, M., Doe, P. J., Doucas, G., Drouin, P. -L., Duncan, F. A., Dunford, M., Earle, E. D., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Gagnon, N., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Harvey, P. J., Hazama, R., Heintzelman, W. J., Heise, J., Helmer, R. L., Hime, A., Howard, C., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Jerkins, M., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Kraus, C., Krauss, C. B., Kruger, A, Kutter, T., Kyba, C. C. M., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R., McCauley, N., McDonald, A. B., McGee, S. R., Miller, M. L., Monreal, B., Monroe, J., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Rosten, R. C., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Simpson, J. J., Skensved, P., Sonley, T. J., Stonehill, L. C., Tešić, G., Tolich, N., Tsui, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Tseung, H. Wan Chan, Wark, D. L., Watson, P. J. S., Wendland, J., West, N., Wilkerson, J. F., Wilson, J. R., Wouters, J. M., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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Nuclear Experiment ,Astrophysics - Solar and Stellar Astrophysics ,High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
We report results from a combined analysis of solar neutrino data from all phases of the Sudbury Neutrino Observatory. By exploiting particle identification information obtained from the proportional counters installed during the third phase, this analysis improved background rejection in that phase of the experiment. The combined analysis resulted in a total flux of active neutrino flavors from 8B decays in the Sun of (5.25 \pm 0.16(stat.)+0.11-0.13(syst.))\times10^6 cm^{-2}s^{-1}. A two-flavor neutrino oscillation analysis yielded \Deltam^2_{21} = (5.6^{+1.9}_{-1.4})\times10^{-5} eV^2 and tan^2{\theta}_{12}= 0.427^{+0.033}_{-0.029}. A three-flavor neutrino oscillation analysis combining this result with results of all other solar neutrino experiments and the KamLAND experiment yielded \Deltam^2_{21} = (7.41^{+0.21}_{-0.19})\times10^{-5} eV^2, tan^2{\theta}_{12} = 0.446^{+0.030}_{-0.029}, and sin^2{\theta}_{13} = (2.5^{+1.8}_{-1.5})\times10^{-2}. This implied an upper bound of sin^2{\theta}_{13} < 0.053 at the 95% confidence level (C.L.).
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- 2011
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13. Measurement of the $\nu_e$ and Total $^{8}$B Solar Neutrino Fluxes with the Sudbury Neutrino Observatory Phase-III Data Set
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Aharmim, B., Ahmed, S. N., Amsbaugh, J. F., Anaya, J. M., Anthony, A. E., Banar, J., Barros, N., Beier, E. W., Bellerive, A., Beltran, B., Bergevin, M., Biller, S. D., Boudjemline, K., Boulay, M. G., Bowles, T. J., Browne, M. C., Bullard, T. V., Burritt, T. H., Cai, B., Chan, Y. D., Chauhan, D., Chen, M., Cleveland, B. T., Cox, G. A., Currat, C. A., Dai, X., Deng, H., Detwiler, J. A., DiMarco, M., Doe, P. J., Doucas, G., Dragowsky, M. R., Drouin, P. -L., Duba, C. A., Duncan, F. A., Dunford, M., Earle, E. D., Elliott, S. R., Evans, H. C., Ewan, G. T., Farine, J., Fergani, H., Fleurot, F., Ford, R. J., Formaggio, J. A., Fowler, M. M., Gagnon, N., Germani, J. V., Goldschmidt, A., Goon, J. TM., Graham, K., Guillian, E., Habib, S., Hahn, R. L., Hallin, A. L., Hallman, E. D., Hamian, A. A., Harper, G. C., Harvey, P. J., Hazama, R., Heeger, K. M., Heintzelman, W. J., Heise, J., Helmer, R. L., Henning, R., Hime, A., Howard, C., Howe, M. A., Huang, M., Jagam, P., Jamieson, B., Jelley, N. A., Keeter, K. J., Klein, J. R., Kormos, L. L., Kos, M., Krueger, A., Kraus, C., Krauss, C. B., Kutter, T., Kyba, C. C. M., Lange, R., Law, J., Lawson, I. T., Lesko, K. T., Leslie, J. R., Loach, J. C., MacLellan, R., Majerus, S., Mak, H. B., Maneira, J., Martin, R., McCauley, N., McDonald, A. B., McGee, S. R., Mifflin, C., Miller, G. G., Miller, M. L., Monreal, B., Monroe, J., Morissette, B., Myers, A. W., Nickel, B. G., Noble, A. J., O'Keeffe, H. M., Oblath, N. S., Ollerhead, R. W., Gann, G. D. Orebi, Oser, S. M., Ott, R. A., Peeters, S. J. M., Poon, A. W. P., Prior, G., Reitzner, S. D., Rielage, K., Robertson, B. C., Robertson, R. G. H., Rollin, E., Schwendener, M. H., Secrest, J. A., Seibert, S. R., Simard, O., Simpson, J. J., Skensved, P., Smith, M. W. E., Sonley, T. J., Steiger, T. D., Stonehill, L. C., Tesic, G., Thornewell, P. M., Tolich, N., Tsui, T., Tunnell, C. D., Van Wechel, T., Van Berg, R., VanDevender, B. A., Virtue, C. J., Wall, B. L., Waller, D., Tseung, H. Wan Chan, Wendland, J., West, N., Wilhelmy, J. B., Wilkerson, J. F., Wilson, J. R., Wouters, J. M., Wright, A., Yeh, M., Zhang, F., and Zuber, K.
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Nuclear Experiment ,Astrophysics - Solar and Stellar Astrophysics ,High Energy Physics - Experiment - Abstract
This paper details the solar neutrino analysis of the 385.17-day Phase-III data set acquired by the Sudbury Neutrino Observatory (SNO). An array of $^3$He proportional counters was installed in the heavy-water target to measure precisely the rate of neutrino-deuteron neutral-current interactions. This technique to determine the total active $^8$B solar neutrino flux was largely independent of the methods employed in previous phases. The total flux of active neutrinos was measured to be $5.54^{+0.33}_{-0.31}(stat.)^{+0.36}_{-0.34}(syst.)\times 10^{6}$ cm$^{-2}$ s$^{-1}$, consistent with previous measurements and standard solar models. A global analysis of solar and reactor neutrino mixing parameters yielded the best-fit values of $\Delta m^2 = 7.59^{+0.19}_{-0.21}\times 10^{-5}{eV}^2$ and $\theta = 34.4^{+1.3}_{-1.2}$ degrees., Comment: 104 pages, 26 figures, 20 tables, submitted to Phys. Rev. C
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- 2011
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14. The Ising Susceptibility Scaling Function
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Chan, Y., Guttmann, A. J., Nickel, B. G., and Perk, J. H. H.
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Condensed Matter - Statistical Mechanics ,High Energy Physics - Theory ,Mathematical Physics - Abstract
We have dramatically extended the zero field susceptibility series at both high and low temperature of the Ising model on the triangular and honeycomb lattices, and used these data and newly available further terms for the square lattice to calculate a number of terms in the scaling function expansion around both the ferromagnetic and, for the square and honeycomb lattices, the antiferromagnetic critical point., Comment: PDFLaTeX, 50 pages, 5 figures, zip file with series coefficients and background data in Maple format provided with the source files. Vs2: Added dedication and made several minor additions and corrections. Vs3: Minor corrections. Vs4: No change to eprint. Added essential square-lattice series input data (used in the calculation) that were removed from University of Melbourne's website
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- 2010
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15. Square lattice Ising model $\tilde{\chi}^{(5)}$ ODE in exact arithmetic
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Nickel, B., Jensen, I., Boukraa, S., Guttmann, A. J., Hassani, S., Maillard, J. -M., and Zenine, N.
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Mathematical Physics ,Condensed Matter - Statistical Mechanics ,34M55, 47E05, 81Qxx, 32G34, 34Lxx, 34Mxx, 14Kxx - Abstract
We obtain in exact arithmetic the order 24 linear differential operator $L_{24}$ and right hand side $E^{(5)}$ of the inhomogeneous equation$L_{24}(\Phi^{(5)}) = E^{(5)}$, where $\Phi^{(5)} =\tilde{\chi}^{(5)}-\tilde{\chi}^{(3)}/2+\tilde{\chi}^{(1)}/120$ is a linear combination of $n$-particle contributions to the susceptibility of the square lattice Ising model. In Bostan, et al. (J. Phys. A: Math. Theor. {\bf 42}, 275209 (2009)) the operator $L_{24}$ (modulo a prime) was shown to factorize into $L_{12}^{(\rm left)} \cdot L_{12}^{(\rm right)}$; here we prove that no further factorization of the order 12 operator $L_{12}^{(\rm left)}$ is possible. We use the exact ODE to obtain the behaviour of $\tilde{\chi}^{(5)}$ at the ferromagnetic critical point and to obtain a limited number of analytic continuations of $\tilde{\chi}^{(5)}$ beyond the principal disk defined by its high temperature series. Contrary to a speculation in Boukraa, et al (J. Phys. A: Math. Theor. {\bf 41} 455202 (2008)), we find that $\tilde{\chi}^{(5)}$ is singular at $w=1/2$ on an infinite number of branches., Comment: 25 pages, 2 figures, IoP style files
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- 2010
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16. P1.17-08 Program Factors Associated with the Psychosocial Outcomes of Lung Cancer Screening: A Systematic Review
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McFadden, K., primary, Nickel, B., additional, Rankin, N., additional, Houssami, N., additional, Li, T., additional, Jennett, C., additional, Sharman, A., additional, Quaife, S., additional, and Dodd, R., additional
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- 2023
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17. Experimental mathematics on the magnetic susceptibility of the square lattice Ising model
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Boukraa, S., Guttmann, A. J., Hassani, S., Jensen, I., Maillard, J. -M., Nickel, B., and Zenine, N.
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Mathematical Physics ,Condensed Matter - Statistical Mechanics ,High Energy Physics - Theory ,34M55, 47E05, 81Qxx, 32G34, 34Lxx, 34Mxx, 14Kxx - Abstract
We calculate very long low- and high-temperature series for the susceptibility $\chi$ of the square lattice Ising model as well as very long series for the five-particle contribution $\chi^{(5)}$ and six-particle contribution $\chi^{(6)}$. These calculations have been made possible by the use of highly optimized polynomial time modular algorithms and a total of more than 150000 CPU hours on computer clusters. For $\chi^{(5)}$ 10000 terms of the series are calculated {\it modulo} a single prime, and have been used to find the linear ODE satisfied by $\chi^{(5)}$ {\it modulo} a prime. A diff-Pad\'e analysis of 2000 terms series for $\chi^{(5)}$ and $\chi^{(6)}$ confirms to a very high degree of confidence previous conjectures about the location and strength of the singularities of the $n$-particle components of the susceptibility, up to a small set of ``additional'' singularities. We find the presence of singularities at $w=1/2$ for the linear ODE of $\chi^{(5)}$, and $w^2= 1/8$ for the ODE of $\chi^{(6)}$, which are {\it not} singularities of the ``physical'' $\chi^{(5)}$ and $\chi^{(6)},$ that is to say the series-solutions of the ODE's which are analytic at $w =0$. Furthermore, analysis of the long series for $\chi^{(5)}$ (and $\chi^{(6)}$) combined with the corresponding long series for the full susceptibility $\chi$ yields previously conjectured singularities in some $\chi^{(n)}$, $n \ge 7$. We also present a mechanism of resummation of the logarithmic singularities of the $\chi^{(n)}$ leading to the known power-law critical behaviour occurring in the full $\chi$, and perform a power spectrum analysis giving strong arguments in favor of the existence of a natural boundary for the full susceptibility $\chi$., Comment: 54 pages, 2 figures
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- 2008
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18. Detailed Examination of Transport Coefficients in Cubic-Plus-Quartic Oscillator Chains
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Lee-Dadswell, G. R., Nickel, B. G., and Gray, C. G.
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Condensed Matter - Statistical Mechanics - Abstract
We examine the thermal conductivity and bulk viscosity of a one-dimensional (1D) chain of particles with cubic-plus-quartic interparticle potentials and no on-site potentials. This system is equivalent to the FPU-alpha beta system in a subset of its parameter space. We identify three distinct frequency regimes which we call the hydrodynamic regime, the perturbative regime and the collisionless regime. In the lowest frequency regime (the hydrodynamic regime) heat is transported ballistically by long wavelength sound modes. The model that we use to describe this behaviour predicts that as the frequency goes to zero the frequency dependent bulk viscosity and the frequency dependent thermal conductivity should diverge with the same power law dependence on frequency. Thus, we can define the bulk Prandtl number as the ratio of the bulk viscosity to the thermal conductivity (with suitable prefactors to render it dimensionless). This dimensionless ratio should approach a constant value as frequency goes to zero. We use mode-coupling theory to predict the zero frequency limit. Values of the bulk Prandtl number from simulations are in agreement with these predictions over a wide range of system parameters. In the middle frequency regime, which we call the perturbative regime, heat is transported by sound modes which are damped by four-phonon processes. We call the highest frequency regime the collisionless regime since at these frequencies the observing times are much shorter than the characteristic relaxation times of phonons. The perturbative and collisionless regimes are discussed in detail in the appendices., Comment: Latex with references in .bib file. 36 pages, 8 figures. Submitted to J. Stat. Phys. on Sept. 27
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- 2007
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19. Controlled nucleation and growth of CdS nanoparticles in a polymer matrix
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Di Luccio, T., Laera, A. M., Tapfer, L., Kempter, S., Kraus, R., and Nickel, B.
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Condensed Matter - Materials Science - Abstract
The nucleation and growth of CdS nanoparticles within a polymer matrix was followed by in-situ synchrotron X-ray diffraction. The nanoparticles form by effect of the thermolysis of thiolate precursors at temperatures between 200 and 300 Celsius degrees. Above 240 Celsius degrees the precursor decomposition is complete and CdS nanoparticles grow in the polymer matrix forming a nanocomposite with interesting optical properties. The nanoparticle structural properties (size and crystal structure) depend on the annealing temperature.(abridged version), Comment: 25 pages, 7 figures, 1 table
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- 2006
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20. Unerwarteter Fund im Bruchsack einer Umbilikalhernie
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Wiedemann, F., Nickel, B., and Kraft, B.
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- 2020
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21. The susceptibility of the square lattice Ising model: New developments
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Orrick, W. P., Nickel, B., Guttmann, A. J., and Perk, J. H. H.
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Condensed Matter - Statistical Mechanics - Abstract
We have made substantial advances in elucidating the properties of the susceptibility of the square lattice Ising model. We discuss its analyticity properties, certain closed form expressions for subsets of the coefficients, and give an algorithm of complexity O(N^6) to determine its first N coefficients. As a result, we have generated and analyzed series with more than 300 terms in both the high- and low-temperature regime. We quantify the effect of irrelevant variables to the scaling-amplitude functions. In particular, we find and quantify the breakdown of simple scaling, in the absence of irrelevant scaling fields, arising first at order |T-T_c|^{9/4}, though high-low temperature symmetry is still preserved. At terms of order |T-T_c|^{17/4} and beyond, this symmetry is no longer present. The short-distance terms are shown to have the form (T-T_c)^p(log|T-T_c|)^q with p \ge q^2. Conjectured exact expressions for some correlation functions and series coefficients in terms of elliptic theta functions also foreshadow future developments., Comment: 49 pages, Contribution to conference proceedings: The Baxter revolution in mathematical physics, Canberra, Australia, 13-19 Feb, 2000
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- 2001
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22. Critical behaviour of the two-dimensional Ising susceptibility
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Orrick, W. P., Nickel, B. G., Guttmann, A. J., and Perk, J. H. H.
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Condensed Matter - Statistical Mechanics - Abstract
We report computations of the short-distance and the long-distance (scaling) contributions to the square-lattice Ising susceptibility in zero field close to T_c. Both computations rely on the use of nonlinear partial difference equations for the correlation functions. By summing the correlation functions, we give an algorithm of complexity O(N^6) for the determination of the first N series coefficients. Consequently, we have generated and analysed series of length several hundred terms, generated in about 100 hours on an obsolete workstation. In terms of a temperature variable, \tau, linear in T/T_c-1, the short-distance terms are shown to have the form \tau^p(ln|\tau|)^q with p>=q^2. To O(\tau^14) the long-distance part divided by the leading \tau^{-7/4} singularity contains only integer powers of \tau. The presence of irrelevant variables in the scaling function is clearly evident, with contributions of distinct character at leading orders |\tau|^{9/4} and |\tau|^{17/4} being identified., Comment: 11 pages, REVTex 4
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- 2000
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23. Addendum-erratum to: 'Nonasymptotic critical behavior from field theory at d=3. II. The ordered-phase case. Phys. Rev. B35, 3585 (1987)
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Bagnuls, C., Bervillier, C., Meiron, D. I., and Nickel, B. G.
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High Energy Physics - Theory ,Condensed Matter - Statistical Mechanics - Abstract
This note is intended to emphasize the existence of estimated Feynman integrals in three dimensions for the free energy of the O(1) scalar theory up to five loops which may be useful for other work. We also correct some misprints of the published paper., Comment: One figure and one table added, some additions in the text
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- 2000
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24. The Linear Baryon
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Bukta, D., Karl, G., and Nickel, B. G.
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Nonlinear Sciences - Chaotic Dynamics - Abstract
We describe classical orbits and quantum states of a three particle system which is weakly chaotic. The quantum energies of the lowest 48 states which are invariant under permutations are given both in various approximations and to high accuracy. The quantum mechanical probability distributions are given in a two dimensional version of the system, the hexagonal pit. The quantum probabilities show strong resemblance to classical orbits of various types, including chaotic ones., Comment: 19 pages, 5 figures
- Published
- 1999
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25. Understanding general practitioners' prescribing choices to patients with chronic low back pain: a discrete choice experiment.
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Hamilton, M, Christine Lin, C-W, Arora, S, Harrison, M, Tracy, M, Nickel, B, Shaheed, CA, Gnjidic, D, Mathieson, S, Hamilton, M, Christine Lin, C-W, Arora, S, Harrison, M, Tracy, M, Nickel, B, Shaheed, CA, Gnjidic, D, and Mathieson, S
- Abstract
BACKGROUND: Although NSAIDs are recommended as a first line analgesic treatment, opioids are very commonly prescribed to patients with low back pain (LBP) despite risks of harms. AIM: This study aimed to determine factors contributing to general practitioners' (GPs') prescribing choices to patients with chronic LBP in a primary care setting. METHOD: This discrete choice experiment (DCE) presented 210 GPs with hypothetical scenarios of a patient with chronic LBP. Participants chose their preferred treatment for each choice set, either the opioid, NSAID or neither. The scenarios varied by two patient attributes; non-specific LBP or LBP with referred leg pain (sciatica) and number of comorbidities. The three treatment attributes also varied, being: the type of opioid or NSAID, degree of pain reduction and number of adverse events. The significance of each attribute in influencing clinical decisions was the primary outcome and the degree to which GPs preferred the alternative based on the number of adverse events or the amount of pain reduction was the secondary outcome. RESULTS: Overall, GPs preferred NSAIDs (45.2%, 95% CI 38.7-51.7%) over opioids (28.8%, 95% CI 23.0-34.7%), however there was no difference between the type of NSAID or opioid preferred. Additionally, the attributes of pain reduction and adverse events did not influence a GP's choice between NSAIDs or opioids for patients with chronic LBP. CONCLUSION: GPs prefer prescribing NSAIDs over opioids for a patient with chronic low back pain regardless of patient factors of comorbidities or the presence of leg pain (i.e. sciatica).
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- 2023
26. Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome
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Edridge, AWD, Abd-Elfarag, G, Deijs, M, Broeks, MH, Cristella, C, Sie, B, Vaz, FM, Jans, JJM, Calis, J, Verhoef, H, Demir, A, Poppert, S, Nickel, B, van Dam, A, Sebit, B, Titulaer, MJ, Verweij, JJ, de Jong, MD, van Gool, T, Faragher, B, Verhoeven-Duif, NM, Elledge, SJ, van der Hoek, L, van Hensbroek, MB, Edridge, AWD, Abd-Elfarag, G, Deijs, M, Broeks, MH, Cristella, C, Sie, B, Vaz, FM, Jans, JJM, Calis, J, Verhoef, H, Demir, A, Poppert, S, Nickel, B, van Dam, A, Sebit, B, Titulaer, MJ, Verweij, JJ, de Jong, MD, van Gool, T, Faragher, B, Verhoeven-Duif, NM, Elledge, SJ, van der Hoek, L, and van Hensbroek, MB
- Abstract
Nodding syndrome is a neglected, disabling and potentially fatal epileptic disorder of unknown aetiology affecting thousands of individuals mostly confined to Eastern sub-Saharan Africa. Previous studies have identified multiple associations - including Onchocerca volvulus, antileiomodin-1 antibodies, vitamin B6 deficiency and measles virus infection - yet, none is proven causal. We conducted a case-control study of children with early-stage nodding syndrome (symptom onset <1 year). Cases and controls were identified through a household survey in the Greater Mundri area in South Sudan. A wide range of parasitic, bacterial, viral, immune-mediated, metabolic and nutritional risk factors was investigated using conventional and state-of-the-art untargeted assays. Associations were examined by multiple logistic regression analysis, and a hypothetical causal model was constructed using structural equation modelling. Of 607 children with nodding syndrome, 72 with early-stage disease were included as cases and matched to 65 household- and 44 community controls. Mansonella perstans infection (odds ratio 7.04, 95% confidence interval 2.28-21.7), Necator americanus infection (odds ratio 2.33, 95% confidence interval 1.02-5.3), higher antimalarial seroreactivity (odds ratio 1.75, 95% confidence interval 1.20-2.57), higher vitamin E concentration (odds ratio 1.53 per standard deviation increase, 95% confidence interval 1.07-2.19) and lower vitamin B12 concentration (odds ratio 0.56 per standard deviation increase, 95% confidence interval 0.36-0.87) were associated with higher odds of nodding syndrome. In a structural equation model, we hypothesized that Mansonella perstans infection, higher vitamin E concentration and fewer viral exposures increased the risk of nodding syndrome while lower vitamin B12 concentration, Necator americanus and malaria infections resulted from having nodding syndrome. We found no evidence that Onchocerca volvulus, antileiomodin-1 antibodies, vit
- Published
- 2023
27. Addressing Behavioral Barriers to COVID-19 Testing With Health Literacy-Sensitive eHealth Interventions: Results From 2 National Surveys and 2 Randomized Experiments.
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Bonner, C, Batcup, C, Cvejic, E, Ayre, J, Pickles, K, Copp, T, Cornell, S, Nickel, B, Dhahir, M, McCaffery, K, Bonner, C, Batcup, C, Cvejic, E, Ayre, J, Pickles, K, Copp, T, Cornell, S, Nickel, B, Dhahir, M, and McCaffery, K
- Abstract
BACKGROUND: Polymerase chain reaction (PCR) testing for COVID-19 was crucial in Australia's prevention strategy in the first 2 years of the pandemic, including required testing for symptoms, contact with cases, travel, and certain professions. However, several months into the pandemic, half of Australians were still not getting tested for respiratory symptoms, and little was known about the drivers of and barriers to COVID-19 PCR testing as a novel behavior at that time. OBJECTIVE: We aimed to identify and address COVID-19 testing barriers, and test the effectiveness of multiple eHealth interventions on knowledge for people with varying health literacy levels. METHODS: The intervention was developed in 4 phases. Phase 1 was a national survey conducted in June 2020 (n=1369), in which testing barriers were coded using the capability-opportunity-motivation-behavior framework. Phase 2 was a national survey conducted in November 2020 (n=2034) to estimate the prevalence of testing barriers and health literacy disparities. Phase 3 was a randomized experiment testing health literacy-sensitive written information for a wide range of barriers between February and March 2021 (n=1314), in which participants chose their top 3 barriers to testing to view a tailored intervention. Phase 4 was a randomized experiment testing 2 audio-visual interventions addressing common testing barriers for people with lower health literacy in November 2021, targeting young adults as a key group endorsing misinformation (n=1527). RESULTS: In phase 1, barriers were identified in all 3 categories: capability (eg, understanding which symptoms to test for), opportunity (eg, not being able to access a PCR test), and motivation (eg, not believing the symptoms are those of COVID-19). Phase 2 identified knowledge gaps for people with lower versus higher health literacy. Phase 3 found no differences between the intervention (health literacy-sensitive text for top 3 barriers) and control groups. Phase 4 show
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- 2023
28. Das Chaos in der Liebeswelt
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Nickel, B., primary
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- 2018
- Full Text
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29. Erratum zu: Seltener histopathologischer Befund bei Skrotalhernie
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Graf, C., Nickel, B., and Kraft, B.
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- 2021
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30. Ungewöhnlicher intraoperativer zystischer Befund bei laparoskopischer Hernioplastik (TAPP) aufgrund einer Skrotalhernie
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Nickel, B. and Kraft, B.
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- 2018
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31. MA04.09 An International Qualitative Study of Healthcare Provider Perspectives of the Psychosocial Impacts and Barriers to Lung Cancer Screening
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McFadden, K., Nickel, B., Houssami, N., Rankin, N., and Dodd, R.
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- 2024
- Full Text
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32. Ungewöhnlicher intraoperativer Befund bei laparoskopischer Fundoplikation wegen paraösophagealer Hiatushernie
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Nickel, B.
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- 2017
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33. Positive outcomes associated with the COVID-19 pandemic in Australia.
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Cornell, S, Nickel, B, Cvejic, E, Bonner, C, McCaffery, KJ, Ayre, J, Copp, T, Batcup, C, Isautier, J, Dakin, T, Dodd, R, Cornell, S, Nickel, B, Cvejic, E, Bonner, C, McCaffery, KJ, Ayre, J, Copp, T, Batcup, C, Isautier, J, Dakin, T, and Dodd, R
- Abstract
ISSUE ADDRESSED: To investigate whether Australians have experienced any positive effects during the COVID-19 pandemic. METHODS: National online longitudinal survey. As part of a June 2020 survey, participants (n = 1370) were asked 'In your life, have you experienced any positive effects from the COVID-19 pandemic' (yes/no) and also completed the World Health Organisation-Five well-being index. Differences were explored by demographic variables. Free-text responses were thematically coded. RESULTS: Nine hundred sixty participants (70%) reported experiencing at least one positive effect during the COVID-19 pandemic. Living with others (P = .045) and employment situation (P < .001) at baseline (April) were associated with experiencing positive effects. Individuals working for pay from home were more likely to experience positive effects compared to those who were not working for pay (aOR = 0.45, 95% CI: 0.32, 0.63, P < .001) or who were working for pay outside the home (aOR = 0.40, 95% CI: 0.28, 0.58, P < .001). 54.2% of participants reported a sufficient level of well-being, 23.2% low well-being and a further 22.6% very low well-being. Of those experiencing positive effects, 945/960 (98%) provided an explanation. The three most common themes were 'Family time' (33%), 'Work flexibility' (29%) and 'Calmer life' (19%). CONCLUSIONS: A large proportion of participants reported positive effects resulting from changes to daily life due to the COVID-19 pandemic in Australia. SO WHAT: The needs of people living alone, and of those having to work outside the home or who are unemployed, should be considered by health policymakers and employers in future pandemic preparedness efforts.
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- 2022
34. Anamorphoscopes another look at circle inverting mirrors
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SHARP, JOHN, NICKEL, B. G., and HUNT, J. L.
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- 2011
35. Preclinical Evaluation of l-Deprenyl: Lack of Amphetamine-Like Abuse Potential
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Yasar, S., Winger, G., Nickel, B., Schulze, G., Goldberg, S. R., and Szelenyi, I., editor
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- 1993
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36. Expression of Human Placental Hormone Genes in Growing and Growth-Inhibited (Transitional) Trophoblasts
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Nachtigal, M. W., Nickel, B. E., Bock, M. E., Lytras, A., Pasumarthi, S. K. B., Cattini, P. A., Soares, Michael J., editor, Talamantes, Frank, editor, and Handwerger, Stuart, editor
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- 1993
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37. Regulation of Gene Expression in the Prostate
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Matusik, R. J., Cattini, P. A., Leco, K. J., Sheppard, P. C., Nickel, B. E., Neubauer, B. L., Davie, J. R., Chang, C., Liao, S., Matuo, Y., McKeehan, W. L., Karr, James P., editor, Coffey, Donald S., editor, Smith, Roy G., editor, and Tindall, Donald J., editor
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- 1991
- Full Text
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38. COVID-19 challenges faced by general practitioners in Australia: a survey study conducted in March 2021
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Copp, T, Isautier, JMJ, Nickel, B, Pickles, K, Tracy, M, Doust, J, Bonner, C, Dodd, RH, Ayre, J, Cvejic, E, Trevena, L, Manocha, R, and McCaffery, KJ
- Subjects
COVID-19 Vaccines ,Cross-Sectional Studies ,General Practitioners ,SARS-CoV-2 ,Australia ,COVID-19 ,Humans ,Public Health ,11 Medical and Health Sciences, 16 Studies in Human Society, 17 Psychology and Cognitive Sciences ,Pandemics - Abstract
Limited studies at the beginning of the COVID-19 pandemic found GPs have been negatively affected by increased workload, reduced income and major concerns about staff and patient safety. This study aimed to investigate the challenges of COVID-19 in general practice 1 year since it was declared a pandemic. A national cross-sectional online survey was conducted in March 2021 of a convenience sample of 295 Australian GPs attending an online educational webcast. Twenty-five multipart and free-text questions collected information regarding GPs' main COVID-19-related issues and concerns, including COVID-19 vaccines, useful sources of information, information needs and their perceived role as GPs in COVID-19 management. Descriptive statistics were calculated for all quantitative variables. Content analysis was used to analyse text data from open-ended questions. Of the 596 eligible attendees of the online educational webcast, 295 completed the survey (49.5% response rate). One year since COVID-19 was declared a pandemic, GPs still have concerns regarding patients ignoring prescreening and presenting with flu-like symptoms, the safety of their colleagues and family and catching COVID-19 themselves, as well as concerns about the effect of the pandemic on their patients and patients delaying essential care for non-COVID-19 conditions. More education and resources about vaccines was identified as the top information need, which will assist with what GPs' perceived to be their key roles in managing the COVID-19 pandemic, namely educating the public, correcting misunderstandings and providing the COVID-19 vaccine. These findings highlight gaps in communication and information, particularly regarding COVID-19 vaccines. GPs need high-quality information and resources to support them in undertaking complex risk communication with their patients.
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- 2021
39. Sensitive Diagnosis and Post-Treatment Follow-Up of Schistosoma mansoni Infections in Asymptomatic Eritrean Refugees by Circulating Anodic Antigen Detection and Polymerase Chain Reaction
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Hoekstra, P.T., Chernet, A., Dood, C.J. de, Brienen, E.A.T., Corstjens, P.L.A.M., Labhardt, N.D., Nickel, B., Wammes, L., Dam, G.J. van, Neumayr, A., and Lieshout, L. van
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Infectious Diseases ,Virology ,Parasitology - Abstract
The increasing number of refugees coming from or passing through Schistosoma-endemic areas and arriving in Europe highlights the importance of screening for schistosomiasis on arrival, and focuses attention on the choice of diagnostic test. We evaluate the diagnostic performance of circulating anodic antigen (CAA) detection in 92 asymptomatic refugees from Eritrea. Results were compared with already-available stool microscopy, serology, and urine point-of-care circulating cathodic antigen (POC-CCA) data. For a full diagnostic comparison, real-time polymerase chain reaction (PCR) and the POC-CCA were included. All outcomes were compared against a composite reference standard. Urine and serum samples were subjected to the ultra-sensitive and highly specific up-converting particle lateral flow CAA test, Schistosoma spp. real-time PCR was performed on urine and stool, and the POC-CCA was used on urine using the G-score method. CAA was detected in 43% of urine and in 40% of serum samples. Urine PCR was negative in all 92 individuals, whereas 25% showed Schistosoma DNA in stool. POC-CCA was positive in 30% of individuals. The CAA test confirmed all microscopy positives, except for two cases that were also negative by all other diagnostic procedures. Post-treatment, a significant reduction in the number of positives and infection intensity was observed, in particular regarding CAA levels. Our findings confirm that microscopy, serology, and POC-CCA lack the sensitivity to detect all active Schistosoma infections. Accuracy of stool PCR was similar to microscopy, indicating that this method also lacks sensitivity. The CAA test appeared to be the most accurate method for screening active Schistosoma infections and for monitoring treatment efficacy.
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- 2021
40. Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of Leishmania spp. in Human Serum
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Tanida, K., Balczun, C., Hahn, A., Veit, A., Nickel, B., Poppert, S., Scheid, P. L., Hagen, R. M., Frickmann, H., Loderstädt, U., and Tannich, E.
- Subjects
in-house ,leishmania ,test comparison ,Medicine ,real-time PCR ,Kala Azar ,visceral ,serum ,Article - Abstract
To perform PCR from serum for the diagnosis of visceral leishmaniasis is convenient and much less invasive than the examination of deeper compartments such as bone marrow. We compared three Leishmania-specific real-time PCRs with three different molecular targets (kinetoplast DNA, the small subunit-ribosomal RNA-(ssrRNA-)gene, the glucose-6-phosphate isomerase-(gpi-)gene) regarding their sensitivity and specificity in human serum. Residual sera from previous diagnostic assessments at the German National Reference Center for Tropical Pathogens Bernhard Nocht Institute for Tropical Medicine Hamburg and the Swiss Tropical and Public Health Institute were used. The sensitivities of kinetoplast DNA-PCR, ssrRNA-gene PCR, and gpi-PCR were 93.3%, 73.3%, and 33.3%, respectively, with 15 initial serum samples from visceral leishmaniasis patients, as well as 9.1%, 9.1%, and 0.0%, respectively, with 11 follow-up serum samples taken at various time points following anti-leishmanial therapy. Specificity was 100.0% in all assays as recorded with 1.137 serum samples from deployed soldiers and migrants without clinical suspicion of visceral leishmaniasis. Kinetoplast-DNA PCR from serum was confirmed as a sensitive and specific approach for the diagnosis of visceral leishmaniasis. The results also indicate the suitability of serum PCR for diagnostic follow-up after therapy, in particular regarding therapeutic failure in case of persisting positive PCR results.
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- 2021
41. Effect of selegiline and desmethyl-selegiline on cortical electric activity in rats
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Nickel, B., Borbe, H. O., Szelenyi, I., Riederer, Peter, editor, and Youdim, Moussa B. H., editor
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- 1990
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42. Kinetic evaluation of MAO-B-activity following oral administration of selegiline and desmethyl-selegiline in the rat
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Borbe, H. O., Niebch, G., Nickel, B., Riederer, Peter, editor, and Youdim, Moussa B. H., editor
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- 1990
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43. StrongNet: An International Network to Improve Diagnostics and Access to Treatment for Strongyloidiasis Control
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Albonico, M, Becker, SL, Odermatt, P, Angheben, A, Anselmi, M, Amor, A, Barda, B, Buonfrate, D, Cooper, P, Gétaz, L, Keiser, J, Khieu, V, Montresor, A, Muñoz, J, Requena-Méndez, A, Savioli, L, Speare, R, Steinmann, P, van Lieshout, L, Utzinger, J, Bisoffi, Z, Ault, S, Bartoloni, A, Bottazzi, ME, Bottieau, E, Bradbury, R, Brattig, N, Calleri, G, Castel, M, Caumes, E, Chiodini, PL, Colli, E, de los Santos, JJ, Einsiedel, L, Ferrero, L, Formenti, F, Forrer, A, Gobbi, F, Gombe-Goetz, S, Gomez, J, Gotuzzo, E, Guevara, A, Kearns, T, Knopp, S, Kotze, A, Krolewiecki, A, Lammie, P, Luchanez, A, Magnussen, P, Marcos, L, Marlais, T, Marti, H, McCarthy, J, Mejia, R, Mena, MA, Mertens, P, Miles, M, Molina, I, Mueller, A, Muth, S, Neumayr, A, Nickel, B, Nutman, T, Olsen, A, Page, W, Perandin, F, Periago, MV, Phongluxa, K, Polman, K, Raso, G, Saboya, M, Sayasone, S, Seixas, J, Sevcsik, AM, Schär, F, Sheorey, H, Shield, Jennifer, Arandes, AS, Steer, A, Streit, A, Tanaka, T, Vercruysse, J, Verdonck, K, Visser, L, Vonghachack, Y, Weber, C, Yajima, A, and Zammarchi, L
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Uncategorized - Abstract
No description supplied
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- 2021
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44. Emergence of cobalt oxide nano-assemblies: X-ray in situ studies bridging the molecular- and macro- length scales
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Grote, L., Zito, C. A., Frank, K., Dippel, A.-C., Reisbeck, P., Pitala, K., Kvashnina, K. O., Bauters, S., Detlefs, B., Ivashko, O., Pandit, P., Rebber, M., Harouna-Mayer, S. Y., Nickel, B., and Koziej, D.
- Abstract
The key to fabricate complex, hierarchical materials is the control of chemical reactions at various length scales. The classical model of nucleation and growth fails to provide sufficient information. Here, we illustrate how modern X-ray spectroscopic and scattering in situ studies bridge the molecular- and macro- length scales for an assembly of CoO polyhedral shape nanocrystals. By combining high energy-resolution fluorescence-detected X-ray absorption near edge structure (HERFD-XANES) measurements and FEFF simulation, we directly access the molecular level of the reaction. We reveal that initially Co(acac)3 rapidly reduces to Co(acac)2 and coordinates to oxygen atoms of two solvent molecules, forming a bis-adduct of the square-planar Co(acac)2 with octahedral coordination. Unlike a classical nucleation and growth mechanism, we observe that nuclie as small as 2 nm assemble into superstructures of 20 nm. The individual nanoparticles and assemblies continue growing at a similar pace. The final assemblies are smaller than 100 nm and maintain their spherical shape, while the nanoparticles reach a size of 6 nm and adopt various polyhedral, edgy shapes. Our work thus provides a comprehensive perspective on the emergence of nano-assemblies in solution
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- 2021
45. X-ray-Based Techniques to Study the Nano-Bio Interface
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Sanchez-Cano, C, Alvarez-Puebla, RA, Abendroth, JM, Beck, T, Blick, R, Cao, Y, Caruso, F, Chakraborty, I, Chapman, HN, Chen, C, Cohen, BE, Conceicao, ALC, Cormode, DP, Cui, D, Dawson, KA, Falkenberg, G, Fan, C, Feliu, N, Gao, M, Gargioni, E, Glueer, C-C, Gruener, F, Hassan, M, Hu, Y, Huang, Y, Huber, S, Huse, N, Kang, Y, Khademhosseini, A, Keller, TF, Koernig, C, Kotov, NA, Koziej, D, Liang, X-J, Liu, B, Liu, S, Liu, Y, Liu, Z, Liz-Marzan, LM, Ma, X, Machicote, A, Maison, W, Mancuso, AP, Megahed, S, Nickel, B, Otto, F, Palencia, C, Pascarelli, S, Pearson, A, Penate-Medina, O, Qi, B, Raedler, J, Richardson, JJ, Rosenhahn, A, Rothkamm, K, Rubhausen, M, Sanyal, MK, Schaak, RE, Schlemmer, H-P, Schmidt, M, Schmutzler, O, Schotten, T, Schulz, F, Sood, AK, Spiers, KM, Staufer, T, Stemer, DM, Stierle, A, Sun, X, Tsakanova, G, Weiss, PS, Weller, H, Westermeier, F, Xu, M, Yan, H, Zeng, Y, Zhao, Y, Zhu, D, Zhu, Y, Parak, WJ, Sanchez-Cano, C, Alvarez-Puebla, RA, Abendroth, JM, Beck, T, Blick, R, Cao, Y, Caruso, F, Chakraborty, I, Chapman, HN, Chen, C, Cohen, BE, Conceicao, ALC, Cormode, DP, Cui, D, Dawson, KA, Falkenberg, G, Fan, C, Feliu, N, Gao, M, Gargioni, E, Glueer, C-C, Gruener, F, Hassan, M, Hu, Y, Huang, Y, Huber, S, Huse, N, Kang, Y, Khademhosseini, A, Keller, TF, Koernig, C, Kotov, NA, Koziej, D, Liang, X-J, Liu, B, Liu, S, Liu, Y, Liu, Z, Liz-Marzan, LM, Ma, X, Machicote, A, Maison, W, Mancuso, AP, Megahed, S, Nickel, B, Otto, F, Palencia, C, Pascarelli, S, Pearson, A, Penate-Medina, O, Qi, B, Raedler, J, Richardson, JJ, Rosenhahn, A, Rothkamm, K, Rubhausen, M, Sanyal, MK, Schaak, RE, Schlemmer, H-P, Schmidt, M, Schmutzler, O, Schotten, T, Schulz, F, Sood, AK, Spiers, KM, Staufer, T, Stemer, DM, Stierle, A, Sun, X, Tsakanova, G, Weiss, PS, Weller, H, Westermeier, F, Xu, M, Yan, H, Zeng, Y, Zhao, Y, Zhu, D, Zhu, Y, and Parak, WJ
- Abstract
X-ray-based analytics are routinely applied in many fields, including physics, chemistry, materials science, and engineering. The full potential of such techniques in the life sciences and medicine, however, has not yet been fully exploited. We highlight current and upcoming advances in this direction. We describe different X-ray-based methodologies (including those performed at synchrotron light sources and X-ray free-electron lasers) and their potentials for application to investigate the nano-bio interface. The discussion is predominantly guided by asking how such methods could better help to understand and to improve nanoparticle-based drug delivery, though the concepts also apply to nano-bio interactions in general. We discuss current limitations and how they might be overcome, particularly for future use in vivo.
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- 2021
46. Anti-Mullerian hormone (AMH) test information on Australian and New Zealand fertility clinic websites: a content analysis
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Copp, T, Nickel, B, Lensen, S, Hammarberg, K, Lieberman, D, Doust, J, Mol, BW, McCaffery, K, Copp, T, Nickel, B, Lensen, S, Hammarberg, K, Lieberman, D, Doust, J, Mol, BW, and McCaffery, K
- Abstract
OBJECTIVES: The anti-Mullerian hormone (AMH) test has been promoted as a way to inform women about their future fertility. However, data consistently show the test is a poor predictor of natural fertility potential for an individual woman. As fertility centre websites are often a primary source of information for reproductive information, it is essential the information provided is accurate and reflects the available evidence. We aimed to systematically record and categorise information about the AMH test found on Australian and New Zealand fertility clinic websites. DESIGN: Content analysis of online written information about the AMH test on fertility clinic websites. SETTING: Accredited Australian and New Zealand fertility clinic websites. METHODS: Data were extracted between April and June 2020. Any webpage that mentioned the AMH test, including blogs specifically about the AMH test posted since 2015, was analysed and the content categorised. RESULTS: Of the 39 active accredited fertility clinics' websites, 25 included information about the AMH test. The amount of information varied widely, and embodied four overarching categories; (1) the utility of the AMH test, (2) who the test is suitable for, (3) possible actions in response to the test and (4) caveats and limitations of the test. Eight specific statements about the utility of the test were identified, many of which are not evidence-based. While some websites were transparent regarding the test's limitations, others mentioned no caveats or included persuasive statements actively promoting the test as empowering for a range of women in different circumstances. CONCLUSIONS: Several websites had statements about the utility of the AMH test that are not supported by the evidence. This highlights the need for higher standards for information provided on fertility clinic websites to prevent women being misled to believe the test can reliably predict their fertility.
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- 2021
47. Authors’ Response to Peer Reviews of “The Psychological Impact of Hypertension During COVID-19 Restrictions: Retrospective Case-Control Study”
- Author
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Bonner, C, Cvejic, E, Ayre, J, Isautier, J, Semsarian, C, Nickel, B, Batcup, C, Pickles, K, Dodd, R, Cornell, S, Copp, T, McCaffery, KJ, Bonner, C, Cvejic, E, Ayre, J, Isautier, J, Semsarian, C, Nickel, B, Batcup, C, Pickles, K, Dodd, R, Cornell, S, Copp, T, and McCaffery, KJ
- Abstract
- Published
- 2021
48. Concerns and motivations about COVID-19 vaccination.
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Dodd, RH, Pickles, K, Nickel, B, Cvejic, E, Ayre, J, Batcup, C, Bonner, C, Copp, T, Cornell, S, Dakin, T, Isautier, J, McCaffery, KJ, Dodd, RH, Pickles, K, Nickel, B, Cvejic, E, Ayre, J, Batcup, C, Bonner, C, Copp, T, Cornell, S, Dakin, T, Isautier, J, and McCaffery, KJ
- Published
- 2021
49. COVID-19 Misinformation Trends in Australia: Prospective Longitudinal National Survey.
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Pickles, K, Cvejic, E, Nickel, B, Copp, T, Bonner, C, Leask, J, Ayre, J, Batcup, C, Cornell, S, Dakin, T, Dodd, RH, Isautier, JMJ, McCaffery, KJ, Pickles, K, Cvejic, E, Nickel, B, Copp, T, Bonner, C, Leask, J, Ayre, J, Batcup, C, Cornell, S, Dakin, T, Dodd, RH, Isautier, JMJ, and McCaffery, KJ
- Abstract
Background: Misinformation about COVID-19 is common and has been spreading rapidly across the globe through social media platforms and other information systems. Understanding what the public knows about COVID-19 and identifying beliefs based on misinformation can help shape effective public health communications to ensure efforts to reduce viral transmission are not undermined. Objective: This study aimed to investigate the prevalence and factors associated with COVID-19 misinformation in Australia and their changes over time. Methods: This prospective, longitudinal national survey was completed by adults (18 years and above) across April (n=4362), May (n=1882), and June (n=1369) 2020. Results: Stronger agreement with misinformation was associated with younger age, male gender, lower education level, and language other than English spoken at home (P<.01 for all). After controlling for these variables, misinformation beliefs were significantly associated (P<.001) with lower levels of digital health literacy, perceived threat of COVID-19, confidence in government, and trust in scientific institutions. Analyses of specific government-identified misinformation revealed 3 clusters: prevention (associated with male gender and younger age), causation (associated with lower education level and greater social disadvantage), and cure (associated with younger age). Lower institutional trust and greater rejection of official government accounts were associated with stronger agreement with COVID-19 misinformation. Conclusions: The findings of this study highlight important gaps in communication effectiveness, which must be addressed to ensure effective COVID-19 prevention.
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- 2021
50. The Psychological Impact of Hypertension During COVID-19 Restrictions: Retrospective Case-Control Study.
- Author
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Bonner, C, Cvejic, E, Ayre, J, Isautier, J, Semsarian, C, Nickel, B, Batcup, C, Pickles, K, Dodd, R, Cornell, S, Copp, T, McCaffery, KJ, Bonner, C, Cvejic, E, Ayre, J, Isautier, J, Semsarian, C, Nickel, B, Batcup, C, Pickles, K, Dodd, R, Cornell, S, Copp, T, and McCaffery, KJ
- Abstract
Background: It is unclear how people with hypertension are responding to the COVID-19 pandemic given their increased risk, and whether targeted public health strategies are needed. Objective: This retrospective case-control study compared people with hypertension to matched healthy controls during the COVID-19 lockdown to determine whether they have higher risk perceptions, anxiety, and vaccination intentions. Methods: Baseline data from a national survey were collected in April 2020 during the COVID-19 lockdown in Australia. People who reported hypertension with no other chronic conditions were randomly matched to healthy controls of similar age, gender, education, and health literacy level. A subset including participants with hypertension was followed up at 2 months after restrictions were eased. Risk perceptions, anxiety, and vaccination intentions were measured in April and June. Results: Of the 4362 baseline participants, 466 (10.7%) reported hypertension with no other chronic conditions. A subset of 1369 people were followed up at 2 months, which included 147 (10.7%) participants with hypertension. At baseline, perceived seriousness was high for both hypertension and control groups. The hypertension group reported greater anxiety compared to the controls and were more willing to vaccinate against influenza, but COVID-19 vaccination intentions were similar. At follow-up, these differences were no longer present in the longitudinal subsample. Perceived seriousness and anxiety had decreased, but vaccination intentions for both influenza and COVID-19 remained high across groups (>80%). Conclusions: Anxiety was above normal levels during the COVID-19 lockdown. It was higher in the hypertension group, which also had higher vaccination intentions. Groups that are more vulnerable to COVID-19 may require targeted mental health screening during periods of greater risk. Despite a decrease in perceived risk and anxiety after 2 months of lockdown restrictions, vaccination
- Published
- 2021
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