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4. The Haloarchaea of Great Salt Lake as Models for Potential Extant Life on Mars

Author

Alexander J. Breda, Mariah P. Slagle, Bradley C. Belasco, Bonnie K. Baxter, Calli B. Cahill, Adrik Z. Da Silva, Nicklaus K. Schlamp, Madelyn Bayles, and Michael J. Regan Jr.

Subjects
Martian, Evaporite, Extant taxon, biology, Haloarchaea, Environmental science, Life on Mars, biology.organism_classification, Halophile, Salt lake, Astrobiology
Published
2020
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5. Cooling Uncovered Foods at a Depth of ∼5.1 cm (2 in.) or Less Poses Little Risk of Pathogen Growth

Author

Nicklaus Koreen, W. Clifton Baldwin, and Donald W. Schaffner

Subjects
Bacillus cereus, Clostridium perfringens, FDA Model Food Code, Retail foods, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641
Abstract

The U.S. Food and Drug Administration has guidelines for cooling cooked foods in retail operations. Data on foodborne illness risk factors in restaurants indicate that cooling is often out of compliance with these guidelines. We sought to identify factors under the control of the operator that had a significant effect on the cooling rates of cooked foods. Minneapolis Minnesota Health Inspectors were trained in standardized operating procedures for cooling data collection. Data loggers set to appropriate time intervals and calibrated to ±0.5 °C (∼1°F) were used in data collection. Analysis was performed using the R statistical computing language version 4.2.2. Preexisting pathogen models were used to predict Log CFU increases of Clostridium perfringens or Bacillus cereus. Data from 224 recipes were recorded by inspectors between October 2018 and October 2019. Food depth had a highly significant effect (p = 8.90E−08) on cooling rate. The use of an ice bath or ice wand was also significant (p

Published
2024
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15. Clinical outcomes of percutaneous coronary intervention in patients turned down for surgical revascularization

Author

Milan Seth, Hitinder S. Gurm, Simon R. Dixon, Elizabeth Pielsticker, Nicklaus K. Slocum, Devraj Sukul, and Mark Zainea

Subjects
Male, medicine.medical_specialty, Michigan, Time Factors, medicine.medical_treatment, Population, Clinical Decision-Making, Myocardial Ischemia, Shock, Cardiogenic, Contrast Media, Eligibility Determination, 030204 cardiovascular system & hematology, Risk Assessment, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Percutaneous Coronary Intervention, Renal Dialysis, Risk Factors, Medicine, Humans, Radiology, Nuclear Medicine and imaging, 030212 general & internal medicine, Hospital Mortality, Registries, Ineligibility, Coronary Artery Bypass, education, Dialysis, Aged, Retrospective Studies, education.field_of_study, business.industry, Cardiogenic shock, Patient Selection, Percutaneous coronary intervention, General Medicine, Middle Aged, medicine.disease, Surgery, Stroke, Treatment Outcome, Cardiothoracic surgery, Conventional PCI, Female, Kidney Diseases, Patient Safety, Cardiology and Cardiovascular Medicine, business
Abstract

Objectives We examined clinical outcomes following percutaneous coronary intervention (PCI) in patients turned down for surgical revascularization across a broad population. Background Prior studies suggest that surgical ineligibility is associated with increased mortality in patients with unprotected left main or multivessel coronary artery disease undergoing PCI. Methods This study included consecutive patients who underwent PCI in a multicenter registry in Michigan from January 2010 to December 2014. Surgical ineligibility required documentation indicating that a cardiac surgeon deemed the patient ineligible for surgery. In-hospital outcomes included mortality (primary outcome), cardiogenic shock, cerebrovascular accident, contrast-induced nephropathy (CIN), and a new requirement for dialysis (NRD). Results Of 99,370 patients at 33 hospitals with on-site surgical backup, 1,922 (1.9%) were surgically ineligible. The rate of ineligibility did not vary by hospital (range: 1.5–2.5%; P = 0.79). Overall, there were no major differences in baseline characteristics or outcomes between surgically ineligible patients and the rest (i.e., nonineligible patients): mortality (0.52% vs. 0.52%; P > 0.5), cardiogenic shock (0.68% vs. 0.73%; P > 0.5), cerebrovascular accident (0.05% vs. 0.19%; P = 0.28), NRD (0.16% vs. 0.19%; P > 0.5), CIN (2.7% vs. 2.3%; P = 0.27). Among 1,074 patients who underwent unprotected left main PCI, 20 (1.9%) were surgically ineligible and experienced increased rates of mortality (20.0% vs. 5.3%; P = 0.022; adjusted OR = 7.38; P

Published
2016

17. Optical bench of the laser ranging interferometer on grace follow-on

Author

Nicklaus, K., primary, Baatzsch, A., primary, Diekmann, C., primary, Gilles, F., primary, Zender, B., primary, Sheard, B., primary, Heinzel, G., primary, Herding, M., primary, Dehne, M., primary, Voss, K., primary, Guenther, B., primary, Böhme, S., primary, Mueller, V., primary, Schuetze, D., primary, and Stede, G., primary

Published
2017
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18. High stability laser for next generation gravity missions

Author

Nicklaus, K., primary, Beller, N., primary, Fitzau, Oliver, primary, Giesberts, M., primary, Barwood, G. P., primary, Williams, R. A., primary, Koegel, H., primary, Gohlke, M., primary, Herding, M., primary, Wang, X., primary, Herper, M., primary, Gill, P., primary, and Webster, S. A., primary

Published
2017
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20. High stability laser for interferometric earth gravity measurements

Author

Nicklaus, K., primary, Herding, M., primary, Beller, N., primary, Fitzau, O., primary, Williams, R. A., primary, Lovelock, P., primary, Gill, P., primary, Dahl, K., primary, Wang, X., primary, Giesberts, M., primary, Herper, M., primary, Barwood, G. P., primary, Koegel, H., primary, and Sell, A., primary

Published
2017
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21. Laser ranging interferometer on Grace follow-on

Author

Dahl, C., primary, Baatzsch, A., primary, Dehne, M., primary, Herding, M., primary, Nicklaus, K., primary, Braxmaier, Claus, primary, Sanjuan, J., primary, Zender, B., primary, Barranco, G. F., primary, Schütze, D., primary, Stede, G., primary, Gilles, F., primary, Hager, P., primary, Voss, K., primary, Abich, K., primary, Gohlke, M., primary, Guenther, B., primary, Görth, A., primary, Mahrdt, C., primary, Müller, V., primary, and Heinzel, G., primary

Published
2017
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23. Passage Effectiveness at a Pool‐and‐Weir Fishway Designed to Accommodate Pacific Lampreys.

Author

Ackerman, Nicklaus K., Pyper, Brian J., David, Margaret M., Wyatt, Garth J., Cramer, Dan P., and Shibahara, Timothy M.

Subjects
LAMPREYS, NATIVE fishes, MIGRATORY animals, FISHWAYS, MIGRATORY fishes
Abstract

Providing passage at man‐made barriers is important to preserving migratory fish species. Fishways used to bypass barriers have historically been designed to provide passage for economically important species, with little regard given to nontarget species. Consequently, native fish species whose swimming behaviors are not well suited to these fishways have suffered from restricted access to habitat. For example, poor passage at dams has contributed to declines in populations of Pacific Lamprey Entosphenus tridentatus in the Columbia River basin. Pool‐and‐weir fishways typical of Columbia basin dams are well suited to salmonids but not to anguilliforms like the Pacific Lamprey. We evaluated the passage efficiency of Pacific Lampreys through a new pool‐and‐weir fishway at River Mill Dam on the Clackamas River, Oregon, that was designed to facilitate Pacific Lamprey passage. Rounded corners at the fishway entrances, flush‐mounted weir gates, chamfered corners on orifices and weir walls, and orifices flush with the floor were all included in the fishway design specifically for Pacific Lampreys. In 2013 and 2015, Pacific Lampreys were radio‐tagged and PIT‐tagged to assess passage success. Dam passage efficiency estimates ranged from 84% to 98%, roughly 10–50% higher than Pacific Lamprey passage efficiency estimates at other dams in the Pacific Northwest. The median passage time through the fishway was 0.87 d in 2013 and 0.71 d in 2015. The high passage efficiency of Pacific Lampreys at River Mill Dam is likely due to the design elements incorporated specifically for Pacific Lampreys. These features could inform future fishway designs and modifications at locations where Pacific Lamprey passage is a consideration. [ABSTRACT FROM AUTHOR]

Published
2019
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27. LASER RANGING INTERFEROMETER ON GRACE FOLLOW-ON.

Author

Dahl, C., Baatzsch, A., Dehne, M., Gilles, F., Hager, P., Herding, M., Nicklaus, K., Voss, K., Abich, K., Braxmaier, C., Gohlke, M., Guenther, B., Sanjuan, J., Zender, B., Barranco, G. F., Görth, A., Mahrdt, C., Müller, V., Schütze, D., and Stede, G.

Published
2017
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31. OUTCOMES AFTER PERCUTANEOUS CORONARY INTERVENTION AMONG PATIENTS WITH A HISTORY OF TRANSIENT ISCHEMIC ATTACK OR CEREBROVASCULAR ACCIDENT: INSIGHTS FROM THE BLUE CROSS BLUE SHIELD OF MICHIGAN CARDIOVASCULAR CONSORTIUM

Author

Hitinder S. Gurm, David Wohns, Milan Seth, Nicklaus K. Slocum, Simon Dixon, and Devraj Sukul

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, BLUE CROSS/BLUE SHIELD, Percutaneous coronary intervention, medicine.disease, Surgery, Coronary artery disease, Internal medicine, Conventional PCI, medicine, Cardiology, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business
Abstract

Background: Due to shared risk factors between coronary artery disease and cerebrovascular disease, patients (pts) with a history of transient ischemic attack (TIA) or cerebrovascular accident (CVA) often undergo percutaneous coronary intervention (PCI). We examined the association between a history

Published
2017
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32. THE CHANGING DEFINITION OF CONTRAST INDUCED NEPHROPATHY AND ITS CLINICAL IMPLICATIONS: INSIGHTS FROM THE BLUE CROSS BLUE SHIELD OF MICHIGAN CARDIOVASCULAR CONSORTIUM (BMC2)

Author

Dean G. Smith, Mauro Moscucci, Hitinder S. Gurm, Nicklaus K. Slocum, David Share, Simon R. Dixon, and Herb Aronow

Subjects
medicine.medical_specialty, business.industry, Ophthalmology, Contrast-induced nephropathy, medicine, BLUE CROSS/BLUE SHIELD, medicine.disease, business, Cardiology and Cardiovascular Medicine
Published
2010
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35. Testing the GRACE follow-on triple mirror assembly

Author

Fleddermann, R, primary, Ward, R L, additional, Elliot, M, additional, Wuchenich, D M, additional, Gilles, F, additional, Herding, M, additional, Nicklaus, K, additional, Brown, J, additional, Burke, J, additional, Dligatch, S, additional, Farrant, D I, additional, Green, K L, additional, Seckold, J A, additional, Blundell, M, additional, Brister, R, additional, Smith, C, additional, Sheard, B S, additional, Heinzel, G, additional, Danzmann, K, additional, Klipstein, B, additional, McClelland, D E, additional, and Shaddock, D A, additional

Published
2014
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36. The design and construction of a prototype lateral-transfer retro-reflector for inter-satellite laser ranging

Author

Ward, R L, primary, Fleddermann, R, additional, Francis, S, additional, Mow-Lowry, C, additional, Wuchenich, D, additional, Elliot, M, additional, Gilles, F, additional, Herding, M, additional, Nicklaus, K, additional, Brown, J, additional, Burke, J, additional, Dligatch, S, additional, Farrant, D, additional, Green, K, additional, Seckold, J, additional, Blundell, M, additional, Brister, R, additional, Smith, C, additional, Danzmann, K, additional, Heinzel, G, additional, Schütze, D, additional, Sheard, B S, additional, Klipstein, W, additional, McClelland, D E, additional, and Shaddock, D A, additional

Published
2014
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40. Laser ranging interferometer on Grace follow-on

Author

Cugny, Bruno, Karafolas, Nikos, Sodnik, Zoran, Dahl, C., Baatzsch, A., Dehne, M., Gilles, F., Hager, P., Herding, M., Nicklaus, K., Voss, K., Abich, K., Braxmaier, C., Gohlke, M., Guenther, B., Sanjuan, J., Zender, B., Barranco, G. F., Görth, A., Mahrdt, C., Müller, V., Schütze, D., Stede, G., and Heinzel, G.

Published
2017
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