268 results on '"Nicolussi P"'
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2. Submanifolds with boundary and Stokes' Theorem in Heisenberg groups
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Di Marco, Marco, Julia, Antoine, Golo, Sebastiano Nicolussi, and Vittone, Davide
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Mathematics - Differential Geometry ,Mathematics - Classical Analysis and ODEs ,Mathematics - Metric Geometry ,53C17, 26B20, 53C65, 58C35 - Abstract
We introduce and study the notion of $C^1_\mathbb{H}$-regular submanifold with boundary in sub-Riemannian Heisenberg groups. As an application, we prove a version of Stokes' Theorem for $C^1_\mathbb{H}$-regular submanifolds with boundary that takes into account Rumin's complex of differential forms in Heisenberg groups., Comment: 30 pages
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- 2024
3. Pandemic data quality modelling: a Bayesian approach in the Italian case
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Ferrari, Luisa, Manzi, Giancarlo, Micheletti, Alessandra, Nicolussi, Federica, and Salini, Silvia
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- 2024
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4. Higher rank inner products, Voronoi tilings and metric degenerations of tori
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Amini, Omid and Nicolussi, Noema
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Mathematics - Metric Geometry ,Mathematics - Algebraic Geometry ,Mathematics - Combinatorics ,Mathematics - Differential Geometry ,Mathematics - Geometric Topology - Abstract
We introduce higher rank inner products on real and complex vector spaces and study their corresponding Voronoi tilings. We use the framework to describe metric degenerations of polarized tori and Hausdorff limits of Voronoi tilings of discrete sets., Comment: 65 pages, 12 figures. Comments welcome!
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- 2023
5. Moduli of Sub-Laplacians on the second Heisenberg group
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Golo, Sebastiano Nicolussi and Warhurst, Ben
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Mathematics - Differential Geometry ,58A20, 22E25, 35R03 - Abstract
We solve the contact equivalence problem for generalised sub-Laplacians on $\He^2$ and show that the family of sub-Laplacians on $\He^2$ modulo contact equivalence, is parameterised by $\R^+$
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- 2023
6. Correction: Pandemic data quality modelling: a Bayesian approach in the Italian case
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Ferrari, Luisa, Manzi, Giancarlo, Micheletti, Alessandra, Nicolussi, Federica, and Salini, Silvia
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- 2024
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7. Curvature exponent and geodesic dimension on Sard-regular Carnot groups
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Golo, Sebastiano Nicolussi and Zhang, Ye
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Mathematics - Metric Geometry ,Mathematics - Differential Geometry ,53C17, 53C23 - Abstract
In this paper we characterize the geodesic dimension $N_{GEO}$ and give a new lower bound to the curvature exponent $N_{CE}$ on Sard-regular Carnot groups. As an application, we give an example of step-two Carnot group on which $N_{CE} > N_{GEO}$: this answers a question posed by Rizzi in arXiv:1510.05960v4 [math.MG].
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- 2023
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8. Capacity of infinite graphs over non-Archimedean ordered fields
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Fischer, Florian, Keller, Matthias, Muranova, Anna, and Nicolussi, Noema
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Mathematics - Analysis of PDEs ,Mathematical Physics ,Mathematics - Spectral Theory ,31C20, 47S10, 05C50, 05C22, 12J15 - Abstract
In this article we study the notion of capacity of a vertex for infinite graphs over non-Archimedean fields. In contrast to graphs over the real field monotone limits do not need to exist. Thus, in our situation next to positive and null capacity there is a third case of divergent capacity. However, we show that either of these cases is independent of the choice of the vertex and is therefore a global property for connected graphs. The capacity is shown to connect the minimization of the energy, solutions of the Dirichlet problem and existence of a Green's function. We furthermore give sufficient criteria in form of a Nash-Williams test, study the relation to Hardy inequalities and discuss the existence of positive superharmonic functions. Finally, we investigate the analytic features of the transition operator in relation to the inverse of the Laplace operator., Comment: 29 pages, 1 figure
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- 2023
9. Improving the power of hypothesis tests in sparse contingency tables
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Nicolussi, Federica, Cazzaro, Manuela, and Rudas, Tamás
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- 2024
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10. Pandemic Data Quality Modelling: A Bayesian Approach
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Ferrari, Luisa, Manzi, Giancarlo, Micheletti, Alessandra, Nicolussi, Federica, and Salini, Silvia
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Statistics - Applications ,Statistics - Other Statistics ,62P10 (Primary), 62F15 (Secondary) - Abstract
When pandemics like COVID-19 spread around the world, the rapidly evolving situation compels officials and executives to take prompt decisions and adapt policies depending on the current state of the disease. In this context, it is crucial for policymakers to have always a firm grasp on what is the current state of the pandemic, and to envision how the number of infections and possible deaths is going to evolve over the next weeks. However, as in many other situations involving compulsory registration of sensitive data from multiple collectors, cases might be reported with errors, often with delays deferring an up-to-date view of the state of things. Errors in collecting new cases affect the overall mortality, resulting in excess deaths reported by official statistics only months later. In this paper, we provide tools for evaluating the quality of pandemic mortality data. We accomplish this through a Bayesian approach accounting for the excess mortality pandemics might bring with respect to the normal level of mortality in the population.
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- 2023
11. ID240 Banho sem enxágue em pacientes acamados: avaliação da eficácia e segurança
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Karoline Faria de Oliveira, Adriana Cristina Nicolussi, Elizabeth Barichello, Thaís Santos Guerra Stacciarini, and Saulo Pereira da Costa
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Banhos ,Cuidados com o Paciente ,Produtos de Higiene Pessoal ,Higiene ,Pharmacy and materia medica ,RS1-441 ,Pharmaceutical industry ,HD9665-9675 - Abstract
Introdução A avaliação do banho no leito sem enxágue foi uma demandada encaminhada ao Núcleo de Avaliação de Tecnologia em Saúde do HC UFTM para avaliação de incorporação na perspectiva hospitalar. O objetivo desta pesquisa foi avaliar a eficácia e segurança do banho sem enxágue em pacientes adultos e idosos que necessitam de cuidados no leito. Métodos Estudo de revisão, utilizando como pergunta norteadora: “O uso do banho sem enxágue é eficaz e seguro em relação ao banho convencional em pacientes adultos e idosos que necessitam de cuidados no leito?” Todas as fases de seleção e extração dos dados foi realizada por três pesquisadores de forma independente e posteriormente realizado consenso das decisões entre os mesmos pesquisadores. O processo seleção dos trabalhos utilizou o fluxograma PRISMA. Os critérios de inclusão foram: Ensaios Clínicos Controlados Randomizados (ECCR) ou estudo quase experimentais que avaliaram os desfechos relacionados à segurança e eficácia do uso do banho sem enxágue em pacientes adultos e idosos que necessitam de cuidados no leito. A busca foi realizada em janeiro de 2023, em seis bases de dados indexadas. Para a combinação da estratégia de busca foram utilizados os termos “Banhos”, “Assistência ao Paciente”, conforme descritor de cada base; e o descritor não controlado “produtos de higiene pessoal”. Foi realizada a avaliação do risco de viés dos estudos (ROB 2 e Robins I). Os desfechos primários avaliados foram os desfechos de segurança (ausência de dermatites e outras reações adversas) e eficácia (controle microbiano e redução de infecção relacionada a assistência à saúde). Como desfechos secundários foram selecionados custo efetividade (economia de insumos, redução de horas de enfermagem), satisfação do profissional, conforto do paciente. Resultados Foram incluídos quatro ECCR e dois estudos quase-experimentais. Três estudos foram classificados como alto risco de viés ou algumas preocupações. Dois estudos avaliaram a colonização da pele e um estudo avaliou a integridade da pele, apontando para uma redução da microbiota da pele e redução significativa de lesões no grupo do banho sem enxágue. Quatro estudos avaliaram o custo, considerando que este foi reduzido no banho a seco, porém, não foi encontrado diferença significativa em três estudos. Quatro estudos avaliaram a satisfação ou sensação de conforto do paciente durante o procedimento, porém essa avaliação foi prejudicada pois dependia do fator memória para ser avaliado, não sendo possível em alguns casos. Não foram encontrados dados relacionados a associação do tipo de banho com infecções relacionadas a assistência à saúde ou que avaliem a resistência bacteriana e a tolerância da pele frente ao uso prolongado destes produtos. Além disso, não foi observado avaliação econômica considerando todos os custos, incluindo àqueles relacionados aos indicadores de infecção. Discussão e conclusões Os estudos clínicos incluídos nesta revisão evidenciam que existe uma direção positiva em relação ao uso do banho sem enxágue, ou seja, o emprego do banho sem enxágue mostrou-se eficaz em relação à redução da microbiota da pele, redução dos custos e das horas de enfermagem, porém, é necessário interpretar os resultados com cautela, haja vista que a qualidade metodológica de alguns estudos analisados. Além disso, desfechos de interesse precisam ser explorados para uma definição mais segura sobre o uso da tecnologia.
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- 2024
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12. Multiproxy tree ring reconstruction of glacier mass balance: insights from Pinus cembra trees growing near Silvretta Glacier (Swiss Alps)
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J. Lopez-Saez, C. Corona, L. Slamova, M. Huss, V. Daux, K. Nicolussi, and M. Stoffel
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Environmental pollution ,TD172-193.5 ,Environmental protection ,TD169-171.8 ,Environmental sciences ,GE1-350 - Abstract
Glacier mass balance reconstructions provide a means of placing relatively short observational records into a longer-term context. Here, we use multiple proxies from Pinus cembra trees from God da Tamangur, combining tree ring anatomy and stable isotope chronologies to reconstruct seasonal glacier mass balance (i.e., winter, summer, and annual mass balance) for the nearby Silvretta Glacier over the last 2 centuries. The combination of tree ring width, radial diameter of earlywood cell lumina, and latewood radial cell wall thickness provides a highly significant reconstruction for summer mass balance, whereas for the winter mass balance, the correlation was less significant but still robust when radial cell lumina were combined with δ18O records. A combination of the reconstructed winter and summer mass balances allows the quantification of the annual mass balance of the Silvretta Glacier for which in situ measurements date back to 1919. Our reconstruction indicates a substantial increase in glacier mass during the first half of the 19th century and an abrupt termination of this phase after the end of the Little Ice Age. Since the 1860s, negative glacier mass balances have been dominant and mass losses accelerate as anthropogenic warming picks up in the Alps.
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- 2024
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13. A note on Spectral Analysis of Quantum graphs
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Nicolussi, Noema
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Mathematics - Spectral Theory ,Primary 81Q35, Secondary 34B45, 35R02, 81Q10 - Abstract
We provide an introductory review of some topics in spectral theory of Laplacians on metric graphs. We focus on three different aspects: the trace formula, the self-adjointness problem and connections between Laplacians on metric graphs and discrete graph Laplacians., Comment: to appear in Internationale Mathematische Nachrichten; 15 pages, 2 figures
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- 2022
14. Classical flows of vector fields with exponential or sub-exponential summability
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Ambrosio, Luigi, Golo, Sebastiano Nicolussi, and Cassano, Francesco Serra
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Mathematics - Classical Analysis and ODEs ,Mathematics - Analysis of PDEs - Abstract
We show that vector fields $b$ whose spatial derivative $D_xb$ satisfies a Orlicz summability condition have a spatially continuous representative and are well-posed. For the case of sub-exponential summability, their flows satisfy a Lusin (N) condition in a quantitative form, too. Furthermore, we prove that if $D_xb$ satisfies a suitable exponential summability condition then the flow associated to $b$ has Sobolev regularity, without assuming boundedness of ${\rm div}_xb$. We then apply these results to the representation and Sobolev regularity of weak solutions of the Cauchy problem for the transport and continuity equations., Comment: 38 pages; Proof of Theorem 6.1 fixed, with a modification of the statements of Theorems 6.1 and D
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- 2022
15. Left-invariant distributions diffeomorphic to flat distributions
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Golo, Sebastiano Nicolussi and Ottazzi, Alessandro
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- 2024
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16. Curvature exponent and geodesic dimension on Sard-regular Carnot groups
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Golo Sebastiano Nicolussi and Zhang Ye
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carnot groups ,curvature exponent ,geodesic dimension ,sub-riemannian geometry ,53c17 ,53c23 ,Analysis ,QA299.6-433 - Abstract
In this study, we characterize the geodesic dimension NGEO{N}_{{\rm{GEO}}} and give a new lower bound to the curvature exponent NCE{N}_{{\rm{CE}}} on Sard-regular Carnot groups. As an application, we give an example of step-two Carnot group on which NCE>NGEO{N}_{{\rm{CE}}}\gt {N}_{{\rm{GEO}}}; this answers a question posed by Rizzi (Measure contraction properties of Carnot groups. Calc. Var. Partial Differential Equations 55 (2016), no. 3, Art. 60, 20).
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- 2024
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17. Moduli of hybrid curves II: Tropical and hybrid Laplacians
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Amini, Omid and Nicolussi, Noema
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Mathematics - Algebraic Geometry ,Mathematics - Combinatorics ,Mathematics - Complex Variables ,Mathematics - Differential Geometry ,Mathematics - Number Theory - Abstract
The present paper is a sequel to our work on hybrid geometry of curves and their moduli spaces. We introduce a notion of hybrid Laplacian, formulate a hybrid Poisson equation, and give a mathematical meaning to the convergence both of the Laplace operator and the solutions to the Poisson equation on Riemann surfaces. As the main theorem of this paper, we then obtain a layered description of the asymptotics of Arakelov Green functions on Riemann surfaces close to the boundary of their moduli spaces. This is done in terms of a suitable notion of hybrid Green functions. As a byproduct of our approach, we obtain other results of independent interest. In particular, we introduce higher rank canonical compactifications of fans and polyhedral spaces and use them to define the moduli space of higher rank tropical curves. Moreover, we develop the first steps of a function theory in higher rank non-Archimedean, hybrid, and tame analysis. Furthermore, we establish the convergence of the Laplace operator on metric graphs toward the tropical Laplace operator on limit tropical curves in the corresponding moduli spaces, leading to new perspectives in operator theory on metric graphs. Our result on the Arakelov Green function is inspired by the works of several authors, in particular those of Faltings, de Jong, Wentworth and Wolpert, and solves a long-standing open problem arising from the Arakelov geometry of Riemann surfaces. The hybrid layered behavior close to the boundary of moduli spaces is expected to be a broad phenomenon and will be explored in our forthcoming work., Comment: 230 pages, 26 figures, comments welcome
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- 2022
18. Optimal $C^\infty$-approximation of functions with exponentially or sub-exponentially integrable derivative
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Ambrosio, Luigi, Golo, Sebastiano Nicolussi, and Cassano, Francesco Serra
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Mathematics - Classical Analysis and ODEs ,Mathematics - Analysis of PDEs ,46E30 (Primary) 35A35 (Secondary) - Abstract
We discuss Meyers-Serrin's type results for smooth approximations of functions $b=b(t,x):\mathbb{R}\times\mathbb{R}^n\to\mathbb{R}^m$, with convergence of an energy of the form \[ \int_{\mathbb{R}}\int_{\mathbb{R}^n} w(t,x) \varphi\left(|Db(t,x)|\right)\mathrm{d} x \mathrm{d} t\,, \] where $w>0$ is a suitable weight function, and $\varphi:[0,\infty)\to [0,\infty)$ is a convex function with $\varphi(0)=0$ having exponential or sub-exponential growth., Comment: 18 pages; remark 25 extended
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- 2022
19. Jet spaces on Carnot groups
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Golo, Sebastiano Nicolussi and Warhurst, Benjamin
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Mathematics - Differential Geometry ,58A20 (Primary) 22E25, 35R03, 32C09 (Secondary) - Abstract
Jet spaces on $\mathbb R^n$ have been shown to have a canonical structure of stratified Lie groups (also known as Carnot groups). We construct jet spaces over stratified Lie groups adapted to horizontal differentiation and show that these jet spaces are themselves stratified Lie groups. Furthermore, we show that these jet spaces support a prolongation theory for contact maps, and in particular, a B\"acklund type theorem holds. A byproduct of these results is an embedding theorem that shows that every stratified Lie group of step $s+1$ can be embedded in a jet space over a stratified Lie group of step $s$., Comment: 33 pages; grant acknowledgments corrected; change terminology Carnot/stratified group; add details to an example
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- 2022
20. Nilpotent groups and biLipschitz embeddings into $L^1$
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Eriksson-Bique, Sylvester, Gartland, Chris, Donne, Enrico Le, Naples, Lisa, and Nicolussi-Golo, Sebastiano
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Mathematics - Metric Geometry ,Mathematics - Analysis of PDEs ,Mathematics - Differential Geometry ,Mathematics - Functional Analysis ,Mathematics - Group Theory - Abstract
We prove that if a simply connected nilpotent Lie group quasi-isometrically embeds into an $L^1$ space, then it is abelian. We reach this conclusion by proving that every Carnot group that biLipschitz embeds into $L^1$ is abelian. Our proof follows the work of Cheeger and Kleiner, by considering the pull-back distance of a Lipschitz map into $L^1$ and representing it using a cut measure. We show that such cut measures, and the induced distances, can be blown up and the blown-up cut measure is supported on "generic" tangents of the original sets. By repeating such a blow-up procedure, one obtains a cut measure supported on half-spaces. This differentiation result then is used to prove that bi-Lipschitz embeddings can not exist in the non-abelian settings.
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- 2021
21. Lipschitz Carnot-Carath\'eodory structures and their limits
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Antonelli, Gioacchino, Donne, Enrico Le, and Golo, Sebastiano Nicolussi
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Mathematics - Metric Geometry ,Mathematics - Classical Analysis and ODEs ,Mathematics - Differential Geometry ,Mathematics - Functional Analysis ,Mathematics - Optimization and Control ,28A75, 53C60, 53C17, 53C23, 49J52, 26A16 - Abstract
In this paper we discuss the convergence of distances associated to converging structures of Lipschitz vector fields and continuously varying norms on a smooth manifold. We prove that, under a mild controllability assumption on the limit vector-fields structure, the distances associated to equi-Lipschitz vector-fields structures that converge uniformly on compact subsets, and to norms that converge uniformly on compact subsets, converge locally uniformly to the limit Carnot-Carath\'eodory distance. In the case in which the limit distance is boundedly compact, we show that the convergence of the distances is uniform on compact sets. We show an example in which the limit distance is not boundedly compact and the convergence is not uniform on compact sets. We discuss several examples in which our convergence result can be applied. Among them, we prove a subFinsler Mitchell's Theorem with continuously varying norms, and a general convergence result for Carnot-Carath\'eodory distances associated to subspaces and norms on the Lie algebra of a connected Lie group.
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- 2021
22. Laplacians on infinite graphs: discrete vs continuous
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Kostenko, Aleksey and Nicolussi, Noema
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Mathematics - Spectral Theory ,Mathematical Physics ,Mathematics - Functional Analysis ,Mathematics - Metric Geometry - Abstract
There are two main notions of a Laplacian operator associated with graphs: discrete graph Laplacians and continuous Laplacians on metric graphs (widely known as quantum graphs). Both objects have a venerable history as they are related to several diverse branches of mathematics and mathematical physics. The existing literature usually treats these two Laplacian operators separately. In this overview, we will focus on the relationship between them (spectral and parabolic properties). Our main conceptual message is that these two settings should be regarded as complementary (rather than opposite) and exactly their interplay leads to important further insight on both sides., Comment: This is an extended version of the invited lecture of one of us (A.K.) at the 8th European Congress of Mathematics in Portoro\v{z}, June 21-26, 2021. arXiv admin note: text overlap with arXiv:2105.09931
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- 2021
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23. Fuentes de las obligaciones, tipicidad progresiva y obligaciones de protección en el ordenamiento italiano
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Andrea Nicolussi
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fuentes de la obligación ,obligaciones de protección ,deberes ,contacto social calificado ,buena fe ,responsabilidad por incumplimiento ,Commercial law ,K1000-1395 ,Civil law ,K623-968 - Abstract
El ensayo aborda el problema contemporáneo de las fuentes de la obligación a la luz del desarrollo del derecho que ha hecho emerger las obligaciones de protección –subespecie de obligaciones en el sentido clásico–. En particular, el artículo 1173 del Código Civil italiano, al prever como fuentes de las obligaciones los hechos o actos capaces de producirlas de conformidad con el ordenamiento jurídico, se abre a una tipicidad progresiva: el juez, aunque no pueda crear obligaciones atípicas en sentido estricto, puede reconocer otras nuevas aplicando principios y normas generales del ordenamiento jurídico. Desde esta perspectiva, la responsabilidad precontractual basada en la obligación de buena fe y otras disposiciones del código civil establecen un principio de protección de la confianza especialmente cuando se trata de actividades profesionales. De ahí una importante innovación que suma a los contratos y hechos ilícitos la confianza surgida de contactos sociales calificados, como fuentes de una responsabilidad que puede denominarse relacional.
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- 2024
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24. A note on the Gaffney Laplacian on infinite metric graphs
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Kostenko, Aleksey and Nicolussi, Noema
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Mathematics - Functional Analysis ,Mathematics - Spectral Theory ,Primary 34B45, Secondary 47B25, 81Q10 - Abstract
We show that the deficiency indices of the minimal Gaffney Laplacian on an infinite locally finite metric graph are equal to the number of finite volume graph ends. Moreover, we provide criteria, formulated in terms of finite volume graph ends, for the Gaffney Laplacian to be closed., Comment: This version of the article is accepted for publication in J. Funct. Anal
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- 2021
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25. Lipschitz functions on submanifolds in Heisenberg groups
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Julia, Antoine, Golo, Sebastiano Nicolussi, and Vittone, Davide
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Mathematics - Metric Geometry ,Mathematics - Classical Analysis and ODEs ,53C17, 58C20, 22E25 - Abstract
We study the behavior of Lipschitz functions on intrinsic $C^1$ submanifolds of Heisenberg groups: our main result is their almost everywhere tangential Pansu differentiability. We also provide two applications: a Lusin-type approximation of Lipschitz functions on $\HH$-rectifiable sets, and a coarea formula on $\HH$-rectifiable sets that completes the program started in~\cite{JNGV}., Comment: 16 pages
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- 2021
26. Lipschitz Carnot-Carathéodory Structures and their Limits
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Antonelli, Gioacchino, Le Donne, Enrico, and Nicolussi Golo, Sebastiano
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- 2023
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27. A Glazman-Povzner-Wienholtz Theorem on graphs
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Kostenko, Aleksey, Malamud, Mark, and Nicolussi, Noema
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Mathematics - Spectral Theory ,Mathematical Physics ,Mathematics - Functional Analysis - Abstract
The Glazman-Povzner-Wienholtz theorem states that the completeness of a manifold, when combined with the semiboundedness of the Schr\"odinger operator $-\Delta + q$ and suitable local regularity assumptions on $q$, guarantees its essential self-adjointness. Our aim is to extend this result to Schr\"odinger operators on graphs. We first obtain the corresponding theorem for Schr\"odinger operators on metric graphs, allowing in particular distributional potentials $q\in H^{-1}_{\rm loc}$. Moreover, we exploit recently discovered connections between Schr\"odinger operators on metric graphs and weighted graphs in order to prove a discrete version of the Glazman-Povzner-Wienholtz theorem., Comment: 24 pages; After submission we learned that the discrete version of the Glazman-Povzner-Wienholtz theorem (Theorem 6.1) was proved earlier by a different approach in arXiv:1301.1304 (see Theorem 2.16 there)
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- 2021
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28. Metric equivalences of Heintze groups and applications to classifications in low dimension
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Kivioja, Ville, Donne, Enrico Le, and Golo, Sebastiano Nicolussi
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Mathematics - Group Theory ,Mathematics - Differential Geometry ,Mathematics - Metric Geometry ,20F67, 53C23, 22E25, 17B70, 20F69, 30L10, 54E40 - Abstract
We approach the quasi-isometric classification questions on Lie groups by considering low dimensional cases and isometries alongside quasi-isometries. First, we present some new results related to quasi-isometries between Heintze groups. Then we will see how these results together with the existing tools related to isometries can be applied to groups of dimension 4 and 5 in particular. Thus we take steps towards determining all the equivalence classes of groups up to isometry and quasi-isometry. We completely solve the classification up to isometry for simply connected solvable groups in dimension 4, and for the subclass of groups of polynomial growth in dimension 5., Comment: 28 pages
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- 2021
29. Nowhere differentiable intrinsic Lipschitz graphs
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Julia, Antoine, Golo, Sebastiano Nicolussi, and Vittone, Davide
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Mathematics - Metric Geometry ,Mathematics - Classical Analysis and ODEs ,53C17, 58C20, 22E25 - Abstract
We construct intrinsic Lipschitz graphs in Carnot groups with the property that, at every point, there exist infinitely many different blow-up limits, none of which is a homogeneous subgroup. This provides counterexamples to a Rademacher theorem for intrinsic Lipschitz graphs., Comment: 9 pages, 2 figures
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- 2021
30. Decreased vitamin D levels in the pediatric population after COVID-19 lockdown
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Paolo Cavarzere, Romina Pausilli, Lara Nicolussi Prinicpe, Rossella Gaudino, Alessandra Guzzo, Gaetano Cantalupo, and Franco Antoniazzi
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Pediatrics ,RJ1-570 - Abstract
Abstract Backgroud SARS-Cov2 infection began to spread worldwide since December 2019; on March 2020, the World Health Organization characterized its related disease, named COVID-19, as a pandemic. In Italy, to contain the spread of infection a severe lockdown in the spring 2020 was instituted. Other less severe restrictions were imposed in the winter 2020–2021 and in the spring 2021. The containment measures caused a series of consequences for the population and, in particular, for children and adolescents that presented psychophysical problems. The aim of this manuscript is to investigate the serum levels of vitamin D in children and adolescents before, during and after the lockdown consequent to COVID-19 pandemic. Methods This is a retrospective cross-sectional study, including all children and adolescents between 1 to 18 years referring to the Pediatric Endocrinology Service of the University Hospital of Verona, Italy, between January 2019 and December 2021. All patients affected by clinical conditions that involve vitamin D metabolism or assuming vitamin D supplementation were excluded. Results In total, 491 children (36.7% males and 63.3% females) were enrolled in this study. The vitamin D levels decreased over time: 28.3 ± 10.2 ng/mL in 2019; 28.2 ± 11.4 ng/mL in 2020 and 24.9 ± 10.1 ng/mL in 2021 (p
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- 2023
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31. Autoimmune adrenal insufficiency in children: a hint for polyglandular syndrome type 2?
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Marta Arrigoni, Paolo Cavarzere, Lara Nicolussi Principe, Rossella Gaudino, and Franco Antoniazzi
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Schmidt’s syndrome ,Autoimmune polyglandular syndrome type 2 ,Primary adrenal insufficiency ,Hashimoto’s thyroiditis ,Case report ,Pediatrics ,RJ1-570 - Abstract
Abstract Background Primary adrenal insufficiency (PAI) in childhood is a life-threatening disease most commonly due to impaired steroidogenesis. Differently from adulthood, autoimmune adrenalitis is a rare condition amongst PAI’s main aetiologies and could present as an isolated disorder or as a component of polyglandular syndromes, particularly type 2. As a matter of fact, autoimmune polyglandular syndrome (APS) type 2 consists of the association between autoimmune Addison’s disease, type 1 diabetes mellitus and/or Hashimoto’s disease. Case presentation We report the case of an 8-year-old girl who presented Addison’s disease and autoimmune thyroiditis at an early stage of life. The initial course of the disease was characterized by numerous crises of adrenal insufficiency, subsequently the treatment was adjusted in a tertiary hospital with improvement of disease control. Conclusions APS type 2 is a rare condition during childhood, probably because it may remain latent for long periods before resulting in the overt disease. We recommend an early detection of APS type 2 and an adequate treatment of adrenal insufficiency in a tertiary hospital. Moreover, we underline the importance of a regular follow-up in patients with autoimmune diseases, since unrevealed and incomplete forms are frequent, especially in childhood.
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- 2023
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32. Sub-Finsler horofunction boundaries of the Heisenberg group
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Fisher, Nate and Golo, Sebastiano Nicolussi
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Mathematics - Metric Geometry ,Mathematics - Group Theory ,53C23 (Primary) 20F18, 20F65 (Secondary) - Abstract
We give a complete analytic and geometric description of the horofunction boundary for polygonal sub-Finsler metrics---that is, those that arise as asymptotic cones of word metrics---on the Heisenberg group. We develop theory for the more general case of horofunction boundaries in homogeneous groups by connecting horofunctions to Pansu derivatives of the distance function., Comment: From the previous version, we changed the title, added a section about the action of the group on the boundary, and made general edits. 29 pages, 11 figures
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- 2020
33. Area-minimizing cones in the Heisenberg group $\mathbb{H}^1$
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Golo, Sebastiano Nicolussi and Ritoré, Manuel
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Mathematics - Metric Geometry ,53C17, 49Q05, 49Q10 - Abstract
We present a characterization of minimal cones of class $C^2$ and $C^1$ in the first Heisenberg group $\mathbb{H}^1$, with an additional set of examples of minimal cones that are not of class $C^1$., Comment: 13 pages; 4 figures. Final version accepted in Ann. Acad. Sci. Fenn. Math
- Published
- 2020
34. Moduli of hybrid curves I: Variations of canonical measures
- Author
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Amini, Omid and Nicolussi, Noema
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Mathematics - Algebraic Geometry ,Mathematics - Combinatorics ,Mathematics - Complex Variables ,Mathematics - Differential Geometry ,Mathematics - Number Theory - Abstract
The present paper is the first in a series devoted to the study of asymptotic geometry of Riemann surfaces and their moduli spaces. We introduce the moduli space of hybrid curves as a new compactification of the moduli space of curves, refining the one obtained by Deligne and Mumford. This is the moduli space for multiscale geometric objects which mix complex and higher rank tropical and non-Archimedean geometries, reflecting both discrete and continuous features. We define canonical measures on hybrid curves which combine and generalize Arakelov-Bergman measures on Riemann surfaces and Zhang measures on metric graphs. We then show that the universal family of canonically measured hybrid curves over this moduli space varies continuously. This provides a precise link between the non-Archimedean Zhang measure and variations of Arakelov-Bergman measures in families of Riemann surfaces, answering a question which has been open since the pioneering work of Zhang on admissible pairing in the nineties., Comment: 65 pages, 4 figures, change of title. Final version, to appear in Annales scientifiques de l'ENS
- Published
- 2020
35. Modelling provincial Covid-19 epidemic data in Italy using an adjusted time-dependent SIRD model
- Author
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Ferrari, Luisa, Gerardi, Giuseppe, Manzi, Giancarlo, Micheletti, Alessandra, Nicolussi, Federica, Biganzoli, Elia, and Salini, Silvia
- Subjects
Statistics - Applications ,Physics - Physics and Society ,Quantitative Biology - Populations and Evolution - Abstract
In this paper we develop a predictive model for the spread of COVID-19 infection at a provincial (i.e. EU NUTS-3) level in Italy by using official data from the Italian Ministry of Health integrated with data extracted from daily official press conferences of regional authorities and from local newspaper websites. This integration is mainly concerned with COVID-19 cause specific death data which are not available at NUTS-3 level from open official data data channels. An adjusted time-dependent SIRD model is used to predict the behavior of the epidemic, specifically the number of susceptible, infected, deceased and recovered people. Predictive model performance is evaluated using comparison with real data.
- Published
- 2020
36. COVID-Pro in Italy: a dashboard for a province-based analysis
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Ferrari, Luisa, Gerardi, Giuseppe, Manzi, Giancarlo, Micheletti, Alessandra, Nicolussi, Federica, and Salini, Silvia
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Quantitative Biology - Populations and Evolution ,Physics - Physics and Society - Abstract
This paper presents an dashboard developed to analyse the outbreak of the Covid-19 infection in Italy considering daily NUTS-3 data on positive cases provided by the Italian Ministry of Health and on deaths derived from Italian regional authorities' official press conferences. Descriptive time series plots are provided together with a map describing the spatial distribution of province cumulative cases and rates. A section on a proposed time-dependent adjusted SIRD model for NUTS-3 regions is also provided in the dashboard.
- Published
- 2020
37. Area of intrinsic graphs and coarea formula in Carnot Groups
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Julia, Antoine, Golo, Sebastiano Nicolussi, and Vittone, Davide
- Subjects
Mathematics - Classical Analysis and ODEs ,Mathematics - Differential Geometry ,Mathematics - Metric Geometry ,53C17, 28A75, 22E30 - Abstract
We consider submanifolds of sub-Riemannian Carnot groups with intrinsic $C^1$ regularity ($C^1_H$). Our first main result is an area formula for $C^1_H$ intrinsic graphs; as an application, we deduce density properties for Hausdorff measures on rectifiable sets. Our second main result is a coarea formula for slicing $C^1_H$ submanifolds into level sets of a $C^1_H$ function.
- Published
- 2020
38. Intrinsic rectifiability via flat cones in the Heisenberg group
- Author
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Julia, Antoine and Golo, Sebastiano Nicolussi
- Subjects
Mathematics - Classical Analysis and ODEs ,Mathematics - Differential Geometry - Abstract
We give a geometric criterion for a topological surface in the first Heisenberg group to be an intrinsic Lipschitz graph, using planar cones instead of the usual open cones., Comment: 5 pages
- Published
- 2020
39. Decreased vitamin D levels in the pediatric population after COVID-19 lockdown
- Author
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Cavarzere, Paolo, Pausilli, Romina, Nicolussi Prinicpe, Lara, Gaudino, Rossella, Guzzo, Alessandra, Cantalupo, Gaetano, and Antoniazzi, Franco
- Published
- 2023
- Full Text
- View/download PDF
40. Autoimmune adrenal insufficiency in children: a hint for polyglandular syndrome type 2?
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Arrigoni, Marta, Cavarzere, Paolo, Nicolussi Principe, Lara, Gaudino, Rossella, and Antoniazzi, Franco
- Published
- 2023
- Full Text
- View/download PDF
41. Uso de la ultrasonografía en la evaluación de la retención urinaria en pacientes críticos
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Karina Rodrigues Lopes, Beatriz Maria Jorge, Maria Helena Barbosa, Elizabeth Barichello, and Adriana Cristina Nicolussi
- Subjects
Unidades de Cuidados Intensivos ,Examen Físico ,Retención Urinaria ,Ultrasonografía ,Enfermería de Cuidados Críticos ,Cateterismo Urinario ,Nursing ,RT1-120 - Abstract
Objetivo: medir el volumen urinario por medio de la ecografía vesical, realizado por una enfermera en pacientes críticos, después de la retirada de la sonda urinaria permanente y verificar los factores relacionados en la retención urinaria. Método: estudio cuantitativo, observacional y transversal, realizado con 37 pacientes críticos de ambos sexos, mayores de 18 años, con retiro de catéter vesical permanente en las últimas 48 horas. Se utilizó un cuestionario con variables sociodemográficas y clínicas y el examen ecográfico. Se utilizó un cuestionario con variables sociodemográficas y clínicas y el examen ecográfico. Los datos fueron presentados a través de distribución de frecuencias, medidas de centralidad y variabilidad, asociación mediante la prueba exacta de Fisher y, para el análisis, regresión logística binomial múltiple. Resultados: de los 37 pacientes, en su mayoría fue de sexo masculino, con una edad média de 54,9 años. La medición del volumen urinario por ecografía osciló entre 332,3 y 950 ml, y el 40,54% de los pacientes presentó retención urinaria. La retención urinaria se asoció significativamente a la aparición de infección urinaria, estreñimiento intestinal y diuresis por rebosamiento espontáneo. Los pacientes con infección del tracto urinario tenían 7,4 veces más probabilidades de tener retención urinaria. Conclusión: la ecografía vesical fue eficaz para medir el volumen urinario después de retirar el catéter urinario permanente y puede contribuir a la detección de retención urinaria.
- Published
- 2023
- Full Text
- View/download PDF
42. Self-adjoint and Markovian extensions of infinite quantum graphs
- Author
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Kostenko, Aleksey, Mugnolo, Delio, and Nicolussi, Noema
- Subjects
Mathematics - Spectral Theory ,Mathematical Physics ,Mathematics - Functional Analysis ,Primary 34B45, Secondary 47B25, 81Q10 - Abstract
We investigate the relationship between one of the classical notions of boundaries for infinite graphs, \emph{graph ends}, and self-adjoint extensions of the minimal Kirchhoff Laplacian on a metric graph. We introduce the notion of \emph{finite volume} for ends of a metric graph and show that finite volume graph ends is the proper notion of a boundary for Markovian extensions of the Kirchhoff Laplacian. In contrast to manifolds and weighted graphs, this provides a transparent geometric characterization of the uniqueness of Markovian extensions, as well as of the self-adjointness of the Gaffney Laplacian -- the underlying metric graph does not have finite volume ends. If however finitely many finite volume ends occur (as is the case of edge graphs of normal, locally finite tessellations or Cayley graphs of amenable finitely generated groups), we provide a complete description of Markovian extensions upon introducing a suitable notion of traces of functions and normal derivatives on the set of graph ends., Comment: to appear in J. London Math. Soc.; 47 pages, 2 figures
- Published
- 2019
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43. Trace formulas and continuous dependence of spectra for the periodic conservative Camassa-Holm flow
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Eckhardt, Jonathan, Kostenko, Aleksey, and Nicolussi, Noema
- Subjects
Mathematics - Spectral Theory ,Mathematics - Classical Analysis and ODEs ,Primary 34L05, 34B07, Secondary 34L15, 37K15 - Abstract
This article is concerned with the isospectral problem \[ -f'' + \frac{1}{4} f = z\omega f + z^2 \upsilon f \] for the periodic conservative Camassa-Holm flow, where $\omega$ is a periodic real distribution in $H^{-1}_{\mathrm{loc}}(\mathbb{R})$ and $\upsilon$ is a periodic non-negative Borel measure on $\mathbb{R}$. We develop basic Floquet theory for this problem, derive trace formulas for the associated spectra and establish continuous dependence of these spectra on the coefficients with respect to a weak$^\ast$ topology., Comment: 16 pages. arXiv admin note: text overlap with arXiv:1801.04612
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- 2019
- Full Text
- View/download PDF
44. Quantum graphs on radially symmetric antitrees
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Kostenko, Aleksey and Nicolussi, Noema
- Subjects
Mathematics - Spectral Theory ,Mathematical Physics ,34B45 (Primary), 35P15, 81Q10, 81Q35 (Secondary) - Abstract
We investigate spectral properties of Kirchhoff Laplacians on radially symmetric antitrees. This class of metric graphs enjoys a rich group of symmetries, which enables us to obtain a decomposition of the corresponding Laplacian into the orthogonal sum of Sturm--Liouville operators. In contrast to the case of radially symmetric trees, the deficiency indices of the Laplacian defined on the minimal domain are at most one and they are equal to one exactly when the corresponding metric antitree has finite total volume. In this case, we provide an explicit description of all self-adjoint extensions including the Friedrichs extension. Furthermore, using the spectral theory of Krein strings, we perform a thorough spectral analysis of this model. In particular, we obtain discreteness and trace class criteria, criterion for the Kirchhoff Laplacian to be uniformly positive and provide spectral gap estimates. We show that the absolutely continuous spectrum is in a certain sense a rare event, however, we also present several classes of antitrees such that the absolutely continuous spectrum of the corresponding Laplacian is $[0,\infty)$.
- Published
- 2019
- Full Text
- View/download PDF
45. Metric Lie groups admitting dilations
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Donne, Enrico Le and Golo, Sebastiano Nicolussi
- Subjects
Mathematics - Metric Geometry ,Mathematics - Group Theory ,54E40 (Primary) 53C30, 54E45 (Secondary) - Abstract
We consider left-invariant distances $d$ on a Lie group $G$ with the property that there exists a multiplicative one-parameter group of Lie automorphisms $(0, \infty)\rightarrow\mathtt{Aut}(G)$, $\lambda\mapsto\delta_\lambda$, so that $ d(\delta_\lambda x,\delta_\lambda y) = \lambda d(x,y)$, for all $x,y\in G$ and all $\lambda>0$. First, we show that all such distances are admissible, that is, they induce the manifold topology. Second, we characterize multiplicative one-parameter groups of Lie automorphisms that are dilations for some left-invariant distance in terms of algebraic properties of their infinitesimal generator. Third, we show that an admissible left-invariant distance on a Lie group with at least one nontrivial dilating automorphism is biLipschitz equivalent to one that admits a one-parameter group of dilating automorphisms. Moreover, the infinitesimal generator can be chosen to have spectrum in $[1,\infty)$. Fourth, we characterize the automorphisms of a Lie group that are a dilating automorphisms for some admissible distance. Finally, we characterize metric Lie groups admitting a one-parameter group of dilating automorphisms as the only locally compact, isometrically homogeneous metric spaces with metric dilations of all factors. Such metric spaces appear as tangents of doubling metric spaces with unique tangents., Comment: 29 pages; minor improvement and Theorem F added
- Published
- 2019
46. Benefits of rescreening newborns of mothers affected by autoimmune hypothyroidism
- Author
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Paolo Cavarzere, Laura Palma, Lara Nicolussi Principe, Monica Vincenzi, Silvana Lauriola, Rossella Gaudino, Virginia Murri, Luigi Lubrano, Giuliana Rossi, Alessia Sallemi, Ermanna Fattori, Marta Camilot, and Franco Antoniazzi
- Subjects
maternal autoimmune hypothyroidism ,neonatal hypothyroidism ,newborn screening ,anti-thyroid antibodies ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Introduction: Infants of mothers with autoimmune hypothyroidism (AH) are at risk of developing late-onset hypothyroidism, often escaping at newborn screening. This condition might be caused both by the action of maternal antibodies and/or by maternal treatment. Objectives: The aim of this study is to evaluate the prevalence of AH in the mothers of children born in Veneto region, Italy, and to define what is the most appropriate management for these newborns. Methods: Newborns of six different hospitals with a mother suffering from AH and with negative neonatal screening for congenital hypothyroidism (CH) were included in the study. Between 15 and 20 days of life, we collected a serum sample for the evaluation of thyroid function (thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3)) and anti-thyroid antibodies. On the same occasion, a capillary blood sampling was performed for a second screening test. Results: Maternal AH has a prevalence of 3.5%. A total of 291 newborns were enrolled from November 2019 to May 2021. Whereas the 11.4% of infants had a slight elevated serum TSH (>6 mU/L) and required a follow-up, only 2 children presented an elevated TSH level at the second screening test. One of these, with the gland in situ, showed persistently elevated serum TSH levels and required treatment with levothyroxine. Conclusions: Maternal AH rarely caused neonatal thyroid dysfunction. We suggest to reassess newborns from mothers with AH 15 days after birth by means of a second neonatal screening test. This procedure avoids false negatives due to maternal thyroid status, is less invasive and cheaper than the serum TSH evaluation, and prevents a long follow-up.
- Published
- 2023
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- View/download PDF
47. Undergraduate nursing students’ knowledge and experience in infusion therapy and peripheral vascular acces
- Author
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Jaciara Tiago Antunes Alvarenga, Adriana Cristina Nicolussi, Aline Maria Pereira Cruz Ramos, Lucas Fernando Antunes Gomes, Damiana Aparecida Trindade Monteiro, and Silmara Elaine Malaguti Toffano
- Subjects
Nursing ,Vascular Access Devices ,Knowledge ,Education, Nursing ,Education, Nursing, Diploma Programs. ,RT1-120 - Abstract
ABSTRACT Objectives: to analyze the knowledge and experience of undergraduate nursing students regarding infusion therapy and peripheral vascular access. Methods: descriptive, cross-sectional, analytical study with 123 undergraduate nursing students who answered a semi-structured instrument. Results: the majority were women, with a median age of 51 years old; 87% considered the teaching received insufficient to perform in clinical practice. The mean overall knowledge score was 78.1 (SD± 8.97). The themes catheter flushing and lock (38.1%), catheter selection (34.2%), infusion equipment (30.9%) and insertion site (30.9%) presented a significant number of errors. Conclusions: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.
- Published
- 2023
- Full Text
- View/download PDF
48. Spectral multipliers and wave equation for sub-Laplacians: lower regularity bounds of Euclidean type
- Author
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Martini, Alessio, Müller, Detlef, and Golo, Sebastiano Nicolussi
- Subjects
Mathematics - Analysis of PDEs ,Mathematics - Classical Analysis and ODEs ,Mathematics - Functional Analysis ,35L05, 35S30, 42B15, 43A22, 58J60 - Abstract
Let $\mathscr{L}$ be a smooth second-order real differential operator in divergence form on a manifold of dimension $n$. Under a bracket-generating condition, we show that the ranges of validity of spectral multiplier estimates of Mihlin--H\"ormander type and wave propagator estimates of Miyachi--Peral type for $\mathscr{L}$ cannot be wider than the corresponding ranges for the Laplace operator on $\mathbb{R}^n$. The result applies to all sub-Laplacians on Carnot groups and more general sub-Riemannian manifolds, without restrictions on the step. The proof hinges on a Fourier integral representation for the wave propagator associated with $\mathscr{L}$ and nondegeneracy properties of the sub-Riemannian geodesic flow., Comment: 47 pages
- Published
- 2018
- Full Text
- View/download PDF
49. The Bernstein problem for Lipschitz intrinsic graphs in the Heisenberg group
- Author
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Nicolussi, Sebastiano and Cassano, Francesco Serra
- Subjects
Mathematics - Differential Geometry ,53C17 (Primary) 49Q20 (Secondary) - Abstract
We prove that, in the first Heisenberg group $\mathbb{H}$, an entire locally Lipschitz intrinsic graph admitting vanishing first variation of its sub-Riemannian area and non-negative second variation must be an intrinsic plane, i.e., a coset of a two dimensional subgroup of $\mathbb{H}$. Moreover two examples are given for stressing result's sharpness., Comment: 29 pages, 2 figures
- Published
- 2018
50. Polarised Lie groups contactomorphic to stratified groups
- Author
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Nicolussi, Sebastiano and Ottazzi, Alessandro
- Subjects
Mathematics - Metric Geometry ,Mathematics - Differential Geometry ,30L10 (Primary) 22E25, 53C30 (Secondary) - Abstract
For a stratified group $G$, we construct a class of polarised Lie groups, which we call modifications of $G$, that are locally contactomorphic to it. Vice versa, we show that if a polarised group is locally contactomorphic to a stratified group $G$, whose Lie algebra has finite Tanaka prolongation, then it must be a modification of $G$., Comment: 20 pages; changes from previous version: reorganization of the paper and improvements in the exposition of the results
- Published
- 2018
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