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Your search keyword '"Nie, Meifeng"' showing total 15 results
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15 results on '"Nie, Meifeng"'

1. Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects

Author

Fu, Rao, Qi, Ruoyao, Xiong, Hualong, Lei, Xing, Jiang, Yao, He, Jinhang, Chen, Feng, Zhang, Liang, Qiu, Dekui, Chen, Yiyi, Nie, Meifeng, Guo, Xueran, Zhu, Yuhe, Zhang, Jinlei, Yue, Mingxi, Cao, Jiali, Wang, Guosong, Que, Yuqiong, Fang, Mujing, Wang, Yingbin, Chen, Yixin, Cheng, Tong, Ge, Shengxiang, Zhang, Jun, Yuan, Quan, Zhang, Tianying, and Xia, Ningshao

Published
2024
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2. Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels

Author

Qi, Ruoyao, Fu, Rao, Lei, Xing, He, Jinhang, Jiang, Yao, Zhang, Liang, Wu, Yangtao, Wang, Siling, Guo, Xueran, Chen, Feng, Nie, Meifeng, Yang, Man, Chen, Yiyi, Zeng, Jing, Xu, Jingjing, Xiong, Hualong, Fang, Mujin, Que, Yuqiong, Yao, Youliang, Wang, Yingbin, Cao, Jiali, Ye, Huiming, Zhang, Yali, Zheng, Zizheng, Cheng, Tong, Zhang, Jun, Lin, Xu, Yuan, Quan, Zhang, Tianying, and Xia, Ningshao

Published
2024
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3. Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters

Author

Zhang, Liang, Jiang, Yao, He, Jinhang, Chen, Junyu, Qi, Ruoyao, Yuan, Lunzhi, Shao, Tiange, Zhao, Hui, Chen, Congjie, Chen, Yaode, Wang, Xijing, Lei, Xing, Gao, Qingxiang, Zhuang, Chunlan, Zhou, Ming, Ma, Jian, Liu, Wei, Yang, Man, Fu, Rao, Wu, Yangtao, Chen, Feng, Xiong, Hualong, Nie, Meifeng, Chen, Yiyi, Wu, Kun, Fang, Mujin, Wang, Yingbin, Zheng, Zizheng, Huang, Shoujie, Ge, Shengxiang, Cheng, Shih Chin, Zhu, Huachen, Cheng, Tong, Yuan, Quan, Wu, Ting, Zhang, Jun, Chen, Yixin, Zhang, Tianying, Li, Changgui, Qi, Hai, Guan, Yi, and Xia, Ningshao

Published
2023
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4. Micronanoparticled risedronate exhibits potent vaccine adjuvant effects

Author

Nie, Meifeng, Wu, Shuyu, Chen, Yiyi, Wu, Yangtao, Chen, Ruitong, Liu, Yue, Yue, Mingxi, Jiang, Yao, Qiu, Dekui, Yang, Man, Wang, Zikang, Gao, Jiahua, Xiong, Hualong, Qi, Ruoyao, He, Jinhang, Zhang, Jinlei, Zhang, Liang, Wang, Yingbin, Fang, Mujin, Que, Yuqiong, Yao, Youliang, Li, Shaowei, Zhang, Jun, Zhao, Qinjian, Yuan, Quan, Zhang, Tianying, and Xia, Ningshao

Published
2024
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6. Glycoprotein E-Displaying Nanoparticles Induce Robust Neutralizing Antibodies and T-Cell Response against Varicella Zoster Virus.

Author

Wang, Hong, Zhang, Sibo, Xue, Wenhui, Zeng, Yarong, Liu, Liqin, Cui, Lingyan, Liu, Hongjing, Zhang, Yuyun, Chen, Lin, Nie, Meifeng, Zhang, Rongwei, Chen, Zhenqin, Hong, Congming, Zheng, Qingbing, Cheng, Tong, Gu, Ying, Li, Tingting, Xia, Ningshao, and Li, Shaowei

Subjects
HERPES zoster vaccines, HERPES zoster, CHICKENPOX vaccines, VARICELLA-zoster virus, CHICKENPOX, FERRITIN
Abstract

The Varicella zoster virus (VZV), responsible for both varicella (chickenpox) and herpes zoster (shingles), presents significant global health challenges. While primary VZV infection primarily affects children, leading to chickenpox, reactivation in later life can result in herpes zoster and associated post-herpetic neuralgia, among other complications. Vaccination remains the most effective strategy for VZV prevention, with current vaccines largely based on the attenuated vOka strains. Although these vaccines are generally effective, they can induce varicella-like rashes and have sparked concerns regarding cell virulence. As a safer alternative, subunit vaccines circumvent these issues. In this study, we developed a nanoparticle-based vaccine displaying the glycoprotein E (gE) on ferritin particles using the SpyCatcher/SpyTag system, termed FR-gE. This FR-gE nanoparticle antigen elicited substantial gE-specific binding and VZV-neutralizing antibody responses in BALB/c and C57BL/6 mice—responses that were up to 3.2-fold greater than those elicited by the subunit gE while formulated with FH002C, aluminum hydroxide, or a liposome-based XUA01 adjuvant. Antibody subclass analysis revealed that FR-gE produced comparable levels of IgG1 and significantly higher levels of IgG2a compared to subunit gE, indicating a Th1-biased immune response. Notably, XUA01-adjuvanted FR-gE induced a significant increase in neutralizing antibody response compared to the live attenuated varicella vaccine and recombinant vaccine, Shingrix. Furthermore, ELISPOT assays demonstrated that immunization with FR-gE/XUA01 generated IFN-γ and IL-2 levels comparable to those induced by Shingrix. These findings underscore the potential of FR-gE as a promising immunogen for the development of varicella and herpes zoster vaccines. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Modulation of Skin Inflammatory Responses by Aluminum Adjuvant

Author

Liao, Yanhang, primary, Sun, Lixiang, additional, Nie, Meifeng, additional, Li, Jiacheng, additional, Huang, Xiaofen, additional, Heng, Shujun, additional, Zhang, Wenlu, additional, Xia, Tian, additional, Guo, Zhuolin, additional, Zhao, Qinjian, additional, and Zhang, Ling-juan, additional

Published
2023
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9. Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine

Author

Wu, Yangtao, primary, Wang, Shaojuan, additional, Zhang, Yali, additional, Yuan, Lunzhi, additional, Zheng, Qingbing, additional, Wei, Min, additional, Shi, Yang, additional, Wang, Zikang, additional, Ma, Jian, additional, Wang, Kai, additional, Nie, Meifeng, additional, Xiao, Jin, additional, Huang, Zehong, additional, Chen, Peiwen, additional, Guo, Huilin, additional, Lan, Miaolin, additional, Xu, Jingjing, additional, Hou, Wangheng, additional, Hong, Yunda, additional, Chen, Dabing, additional, Sun, Hui, additional, Xiong, Hualong, additional, Zhou, Ming, additional, Liu, Che, additional, Guo, Wenjie, additional, Guo, Huiyu, additional, Gao, Jiahua, additional, Gan, Congling, additional, Li, Zhixiong, additional, Zhang, Haitao, additional, Wang, Xinrui, additional, Li, Shaowei, additional, Cheng, Tong, additional, Zhao, Qinjian, additional, Chen, Yixin, additional, Wu, Ting, additional, Zhang, Tianying, additional, Zhang, Jun, additional, Cao, Hua, additional, Zhu, Huachen, additional, Yuan, Quan, additional, Guan, Yi, additional, and Xia, Ningshao, additional

Published
2022
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10. Intranasal delivery of NS1-deleted influenza virus vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response

Author

Zhang, Liang, primary, Jiang, Yao, additional, He, Jinhang, additional, Chen, Junyu, additional, Qi, Ruoyao, additional, Yuan, Lunzhi, additional, Shao, Tiange, additional, Chen, Congjie, additional, Chen, Yaode, additional, Wang, Xijing, additional, Lei, Xing, additional, Gao, Qingxiang, additional, Zhuang, Chunlan, additional, Zhou, Ming, additional, Ma, Jian, additional, Liu, Wei, additional, Yang, Man, additional, Fu, Rao, additional, Wu, Yangtao, additional, Chen, Feng, additional, Xiong, Hualong, additional, Nie, Meifeng, additional, Chen, Yiyi, additional, Wu, Kun, additional, Fang, Mujing, additional, Wang, Yingbin, additional, Zheng, Zizheng, additional, Huang, Shoujie, additional, Ge, Shengxiang, additional, Cheng, Shih-Chin, additional, Zhu, Huachen, additional, Chen, Tong, additional, Yuan, Quan, additional, Wu, Ting, additional, Zhang, Jun, additional, Chen, Yixin, additional, Zhang, Tianying, additional, Qi, Hai, additional, Guan, Yi, additional, and Xia, Ningshao, additional

Published
2022
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12. A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice

Author

Liu, Liqin, primary, Chen, Tingting, additional, Zhou, Lizhi, additional, Sun, Jie, additional, Li, Yuqian, additional, Nie, Meifeng, additional, Xiong, Hualong, additional, Zhu, Yuhe, additional, Xue, Wenhui, additional, Wu, Yangtao, additional, Li, Tingting, additional, Zhang, Tianying, additional, Kong, Zhibo, additional, Yu, Hai, additional, Zhang, Jun, additional, Gu, Ying, additional, Zheng, Qingbing, additional, Zhao, Qinjian, additional, Xia, Ningshao, additional, and Li, Shaowei, additional

Published
2022
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13. A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters

Author

Wu, Yangtao, primary, Huang, Xiaofen, additional, Yuan, Lunzhi, additional, Wang, Shaojuan, additional, Zhang, Yali, additional, Xiong, Hualong, additional, Chen, Rirong, additional, Ma, Jian, additional, Qi, Ruoyao, additional, Nie, Meifeng, additional, Xu, Jingjing, additional, Zhang, Zhigang, additional, Chen, Liqiang, additional, Wei, Min, additional, Zhou, Ming, additional, Cai, Minping, additional, Shi, Yang, additional, Zhang, Liang, additional, Yu, Huan, additional, Hong, Junping, additional, Wang, Zikang, additional, Hong, Yunda, additional, Yue, Mingxi, additional, Li, Zonglin, additional, Chen, Dabing, additional, Zheng, Qingbing, additional, Li, Shaowei, additional, Chen, Yixin, additional, Cheng, Tong, additional, Zhang, Jun, additional, Zhang, Tianying, additional, Zhu, Huachen, additional, Zhao, Qinjian, additional, Yuan, Quan, additional, Guan, Yi, additional, and Xia, Ningshao, additional

Published
2021
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14. Sterilizing immunity against SARS-CoV-2 in hamsters conferred by a novel recombinant subunit vaccine

Author

Wu, Yangtao, primary, Huang, Xiaofen, additional, Yuan, Lunzhi, additional, Wang, Shaojuan, additional, Zhang, Yali, additional, Xiong, Hualong, additional, Chen, Rirong, additional, Ma, Jian, additional, Qi, Ruoyao, additional, Nie, Meifeng, additional, Xu, Jingjing, additional, Zhang, Zhigang, additional, Chen, Liqiang, additional, Wei, Min, additional, Zhou, Ming, additional, Cai, Minping, additional, Shi, Yang, additional, Zhang, Liang, additional, Yu, Huan, additional, Hong, Junping, additional, Wang, Zikang, additional, Hong, Yunda, additional, Yue, Mingxi, additional, Li, Zonglin, additional, Chen, Dabing, additional, Zheng, Qingbing, additional, Li, Shaowei, additional, Chen, Yixin, additional, Cheng, Tong, additional, Zhang, Jun, additional, Zhang, Tianying, additional, Zhu, Huachen, additional, Zhao, Qinjian, additional, Yuan, Quan, additional, Guan, Yi, additional, and Xia, Ningshao, additional

Published
2020
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15. SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates

Author

Li, Tingting, primary, Zheng, Qingbing, additional, Yu, Hai, additional, Wu, Dinghui, additional, Xue, Wenhui, additional, Xiong, Hualong, additional, Huang, Xiaofen, additional, Nie, Meifeng, additional, Yue, Mingxi, additional, Rong, Rui, additional, Zhang, Sibo, additional, Zhang, Yuyun, additional, Wu, Yangtao, additional, Wang, Shaojuan, additional, Zha, Zhenghui, additional, Chen, Tingting, additional, Deng, Tingting, additional, Wang, Yingbin, additional, Zhang, Tianying, additional, Chen, Yixin, additional, Yuan, Quan, additional, Zhao, Qinjian, additional, Zhang, Jun, additional, Gu, Ying, additional, Li, Shaowei, additional, and Xia, Ningshao, additional

Published
2020
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