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213 results on '"Nijjar, Prabhjot S"'

13. Reply to Poullis

Author

Arriola-Montenegro, Jose, primary, Tandon, Rishabh, additional, and Nijjar, Prabhjot S, additional

Published
2024
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18. Impact of lung transplantation on diastolic dysfunction in recipients with pretransplant pulmonary hypertension

Author

Aggarwal, Rishav, primary, Potel, Koray N., additional, Jackson, Scott, additional, Lemke, Nicholas T., additional, Kelly, Rosemary F., additional, Soule, Matthew, additional, Diaz-Gutierrez, Ilitch, additional, Shumway, Sara J., additional, Patil, Jagadish, additional, Hertz, Marshall, additional, Nijjar, Prabhjot S., additional, and Huddleston, Stephen J., additional

Published
2023
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21. Ventricular septal defect following mitral valve replacement.

Author

Arriola-Montenegro, Jose, Tandon, Rishabh, Shaffer, Andrew, and Nijjar, Prabhjot S

Subjects
VENTRICULAR septal defects, MITRAL valve, VENTRICULAR outflow obstruction, MITRAL valve prolapse, MITRAL valve surgery, MITRAL valve insufficiency, AORTIC valve surgery, TRANSESOPHAGEAL echocardiography
Abstract

Mitral valve surgery (MVS), with repair preferred to replacement, is a common procedure for the treatment of severe primary mitral regurgitation related to leaflet prolapse. Structural complications after MVS include left ventricular outflow obstruction, paravalvular leak and atrial septal defect. Intraoperative transoesophageal echocardiography and predischarge transthoracic echocardiography (TTE) specifically screen for these complications. Ventricular septal defect (VSD), a known complication after aortic valve surgery, is rarely reported after MVS. Recently, unsuccessful valvuloplasty prior to replacement was suggested as a risk factor. We present such a case and explore mechanisms with advanced cardiac imaging. In this case, the patient was found to have an elongated membranous septum that likely predisposed her to septal injury. Finally, we provide guidance on specific transoesophageal/transthoracic echocardiography views to avoid a missed diagnosis. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Performance of computed tomographic angiography–based aortic valve area for assessment of aortic stenosis

Author

Ash, Jerry, Sandhu, Gurmandeep S., Arriola-Montenegro, Jose, Agakishiev, Dzhalal, Clavel, Marie-Annick, Pibarot, Philippe, Duval, Sue, Nijjar, Prabhjot S., Ash, Jerry, Sandhu, Gurmandeep S., Arriola-Montenegro, Jose, Agakishiev, Dzhalal, Clavel, Marie-Annick, Pibarot, Philippe, Duval, Sue, and Nijjar, Prabhjot S.

Abstract

Background A total of 40% of patients with severe aortic stenosis (AS) have low‐gradient AS, raising uncertainty about AS severity. Aortic valve calcification, measured by computed tomography (CT), is guideline‐endorsed to aid in such cases. The performance of different CT‐derived aortic valve areas (AVAs) is less well studied. Methods and Results Consecutive adult patients with presumed moderate and severe AS based on echocardiography (AVA measured by continuity equation on echocardiography <1.5 cm2) who underwent cardiac CT were identified retrospectively. AVAs, measured by direct planimetry on CT (AVACT) and by a hybrid approach (AVA measured in a hybrid manner with echocardiography and CT [AVAHybrid]), were measured. Sex‐specific aortic valve calcification thresholds (≥1200 Agatston units in women and ≥2000 Agatston units in men) were applied to adjudicate severe or nonsevere AS. A total of 215 patients (38.0% women; mean±SD age, 78±8 years) were included: normal flow, 59.5%; and low flow, 40.5%. Among the different thresholds for AVACT and AVAHybrid, diagnostic performance was the best for AVACT <1.2 cm2 (sensitivity, 85%; specificity, 26%; and accuracy, 72%), with no significant difference by flow status. The percentage of patients with correctly classified AS severity (correctly classified severe AS+correctly classified moderate AS) was as follows; AVA measured by continuity equation on echocardiography <1.0 cm2, 77%; AVACT <1.2 cm2, 73%; AVACT <1.0 cm2, 58%; AVAHybrid <1.2 cm2, 59%; and AVAHybrid <1.0 cm2, 45%. AVACT cut points of 1.52 cm2 for normal flow and 1.56 cm2 for low flow, provided 95% specificity for excluding severe AS. Conclusions CT‐derived AVAs have poor discrimination for AS severity. Using an AVACT <1.2‐cm2 threshold to define severe AS can produce significant error. Larger AVACT thresholds improve specificity.

Published
2023

34. Incidental coronary calcium in cancer patients treated with anthracycline and/or trastuzumab

Author

Hooks, Matthew, primary, Sandhu, Gurmandeep, additional, Maganti, Tejaswini, additional, Chen, Ko-Hsuan Amy, additional, Wang, Michelle, additional, Cullen, Ryan, additional, Velangi, Pratik S, additional, Gu, Christina, additional, Wiederin, Jason, additional, Connett, John, additional, Brown, Roland, additional, Blaes, Anne, additional, Shenoy, Chetan, additional, and Nijjar, Prabhjot S, additional

Published
2022
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43. Sex Differences in Patients With Suspected Cardiac Sarcoidosis Assessed by Cardiovascular Magnetic Resonance Imaging

Author

Kalra, Rajat, primary, Malik, Shray, additional, Chen, Ko-Hsuan Amy, additional, Ogugua, Fredrick, additional, Athwal, Pal Satyajit Singh, additional, Elton, Andrew C., additional, Velangi, Pratik S., additional, Ismail, Mohamed F., additional, Chhikara, Sanya, additional, Markowitz, Jeremy S., additional, Nijjar, Prabhjot S., additional, von Wald, Lisa, additional, Roukoz, Henri, additional, Bhargava, Maneesh, additional, Perlman, David, additional, and Shenoy, Chetan, additional

Published
2021
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44. Long-term prognostic value of right ventricular dysfunction on cardiovascular magnetic resonance imaging in anthracycline-treated cancer survivors

Author

Chhikara, Sanya, primary, Hooks, Matthew, additional, Athwal, Pal Satyajit Singh, additional, Hughes, Andrew, additional, Ismail, Mohamed F, additional, Joppa, Stephanie, additional, Velangi, Pratik S, additional, Nijjar, Prabhjot S, additional, Blaes, Anne H, additional, and Shenoy, Chetan, additional

Published
2021
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46. Long-term prognostic value of right ventricular dysfunction on cardiovascular magnetic resonance imaging in anthracycline-treated cancer survivors.

Author

Chhikara, Sanya, Hooks, Matthew, Athwal, Pal Satyajit Singh, Hughes, Andrew, Ismail, Mohamed F, Joppa, Stephanie, Velangi, Pratik S, Nijjar, Prabhjot S, Blaes, Anne H, and Shenoy, Chetan

Subjects
MORTALITY risk factors, HEART failure risk factors, HEART transplantation, CARDIOTOXICITY, ANTHRACYCLINES, VENTRICULAR ejection fraction, MAJOR adverse cardiovascular events, MAGNETIC resonance imaging, HEART assist devices, CANCER patients, TREATMENT effectiveness, RIGHT ventricular dysfunction, HOSPITAL care, CARDIAC arrest, VENTRICULAR arrhythmia, KAPLAN-Meier estimator, DISEASE prevalence, TUMORS, RESUSCITATION, PROPORTIONAL hazards models, DISEASE risk factors
Abstract

Aims We aimed to determine the prevalence of right ventricular (RV) systolic dysfunction on cardiovascular magnetic resonance imaging (CMR) and its impact on long-term adverse outcomes in a large cohort of cancer survivors treated with anthracycline-based chemotherapy. Methods and results Consecutive cancer survivors treated with anthracyclines who underwent clinical CMR for suspected anthracycline-related cardiomyopathy were studied. The primary endpoint was a composite of all-cause death or major adverse cardiac events (MACE): heart failure hospitalization, heart transplantation, ventricular assist device implantation, resuscitated cardiac arrest, or life-threatening ventricular arrhythmia. The secondary endpoints were all-cause death, and cardiac death or MACE. Among 249 survivors who underwent CMR at a median of 2.9 years after cancer treatment, RV systolic dysfunction was present in 54 (21.7%). Of these, 50 (92.6%) had an abnormal left ventricular ejection fraction (LVEF). At a median follow-up time after the CMR of 2.7 years, 105 survivors experienced the primary endpoint. On Kaplan–Meier analyses, the cumulative incidence of the primary endpoint was significantly higher in survivors with abnormal RVEF compared with those with normal RVEF (P  = 0.002). However, on Cox multivariable analyses, RVEF was not associated with the primary endpoint (HR 1.04 per 5% decrease; 95% CI 0.93–1.17; P  = 0.46) after adjustment for non-imaging variables and LVEF. RVEF was also not associated with the secondary endpoints. Conclusion Among anthracycline-treated cancer survivors undergoing CMR for suspected cardiotoxicity, RV systolic dysfunction was present in one in five cases, accompanied by LV systolic dysfunction in nearly all cases, and was not independently associated with long-term outcomes. [ABSTRACT FROM AUTHOR]

Published
2022
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49. Myocardial damage assessed by late gadolinium enhancement on cardiovascular magnetic resonance imaging in cancer patients treated with anthracyclines and/or trastuzumab

Author

Modi, Kalpit, primary, Joppa, Stephanie, additional, Chen, Ko-Hsuan Amy, additional, Athwal, Pal Satyajit Singh, additional, Okasha, Osama, additional, Velangi, Pratik S, additional, Hooks, Matthew, additional, Nijjar, Prabhjot S, additional, Blaes, Anne H, additional, and Shenoy, Chetan, additional

Published
2020
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