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1. Clinical characteristics and management of patients with diabetes mellitus and stable coronary artery disease in daily clinical practice. The SCAD–DM Registry

Author

Maria E. Marketou, Charalambos Vlachopoulos, George Hahalis, Kristalenia Kafkala, Nikolaos Kouvelas, Ioannis Mantas, Antonios Sideris, Evaggelos Pisimisis, Emmanouel P. Vardas, Stylianos Tzeis, Panos E. Vardas, Vassiliki Dimitroula, Christos Hatjielefteriou, Nikolaos Kampouridis, Georgios Karakostas, Athanasios Karanasios, Stylianos Lambropoulos, Fotios Papalisandrou, Emmanouil Scoubourdis, Nikolaos Smirnioudis, Eleftherios Adamopoulos, Georgios Aggelopoulos, Charalampos Albanis, Alexandros Amaslidis, Maria Andreopoulou, Ilias Antoniou, Ilias Apostolou, Georgios Afaras, Vasileios Arfaras, Konstantinos Aronis, Georgios Askar, Christos Athanasiou, Sokratis Avlonitis Antonios Beroukas, Emmanouil Chorozopoulos, Nikolaos Chrysomallis, Konstantinos Davos, Eftichia Demerouti, Vasileios Dimopoulos, Nikolaos Dimoulis, Vasileios Drakoulidis, Kiriaki Faka, Dimitrios Fotiadis, Alexandros Galapis, Antonios Giakoumis, Ioannis Goupios, Christos Harbas, Vasileios Hatjiioakeimidis, Georgios Hondrokoukis, Panagiotis Kalaras, Marina Kanakaraki, Konstantinos Kapetanios, Vasileios Karasavvidis, Theodoros Karonis, Andreas Karydakis, Christos Katsaris, Christos Katsikas, Konstantinos Katsas, Sokratis Kazantzidis, Nikolaos Kipouridis, Eirini Kokani, Georgios Kolios, Ilias Konstantinidis, Themistoklis Konstantinou, Marios Konstantinou, Georgios Kontopoulos, Georgios Kontoroupis, Georgios Koroniotis, Apostolos Kotidis, Chrysanthi Koukosi, Mihail Kouremetis, Christos Kouris, Georgios Kouskos, Konstantinos Koutras, Georgios Koutsibanis, Harikleia Krontira, Konstantinos Lalenis, Christos Liatas, Leonidas Lillis, Grigorios Limperatos, Emmanouil Liodakis, Stavros Liropoulos, Ioannis Livaditis, Dimitrios Logothetis, Maria Lolaka, Georgios Loukidelis, Georgios Mablekos, Antonios Manousakis, Nikolaos Marinakis, Dimitrios Markou, Virginia Markou, Anestis Matziridis, Panagiotis Mavraganis, Vasileios Mavridis, Ioannis Mavrodimitrakis, Georgios Migias, Dimitrios Mitropoulos, Christos Mitroulas, Savvas Nikiforos, Vasileios Nikolaidis, Christos Nikopoulos, Nikoloaos Oikonomidis, Konstantinos Panagiotopoulos, Georgios Panagoulias, Anna Panou, Ioannis Pantelakis, Achilleas Papadopoulos, Apostolos Papadopoulos, Georgios Papaioannou, Andreas Papamichail, Soultana Papanastasiou, Panagiotis Papas, Eleftherios Papavasileiou, Vasileios Papavasileiou, Athanasios Patialiakas, Alexandros Patsilinakos, Georgios Pechlivanidis, Spiridon Petrogiannis, Nikolaos Pontikakis, Charalampos Parissis, Fotios Patsourakos, Evangelos Pisimisis, Andreas Pittaras, Sotirios Plastiras, Athanasios Platis, Panagiotis Poulikarakos, Markos Prionidis, Paraskevi Psarogianni, Emmanouil Psathakis, Dimitrios Psirropoulos, Maria Riga, Ali Risgits, Evangelos Rosmarakis, Maria Samartzi, Isidoros Sarris, Konstantinos Sassalos, Dimitrios Savvalas, Georgios Siliogas, David Simeonidis, Loukas Sinos, Andreas Skanavis, Achilleas Skordas, Vassiliki Sklirou, Iason Skotiniotis, Anastasios Spanos, Dimitrios Sratech, Christos Stathopoulos, Rafail Stavropoulos, Christos Stavrotheodoros, Emmanouil Stefanakis, Konstantinos Stefanis, Christos Stefopoulos, Dimitrios Stergiou, Konstantinos Svolis, Konstantinos Toulis, Kallinikos Tsakonas, Nikolaos Tsamis, Eleni Tzamtzi-Mastaka, Georgios Tzeltzes, Ioannis Tsiantis, Theodora Tsiotika, Vasileios Vachliotis, Ioannis Vakalis, Konstantinos Vardakis, Alexandros Vassilopoulos, Georgia Vlahou, Vasileios Vogas, Evropia Voukelatou, Nikiforos Vrettos, Dionisios Xenos, Konstantinos Zagoridis, Tsilla Zafiriou, Christos Zafiris, Maria Zaharia, Fanourios Zampetakis, and Vasileios Zouganelis

Subjects
diabetes mellitus, coronary artery disease, angina, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Background: Patients with diabetes mellitus (DM) and coronary artery disease (CAD) represent a high-risk population, where comorbidities are common and the progression of coronary heart disease is relatively rapid and extensive. The present survey, conducted nationwide in a Eurozone country, Greece, with a properly organized national health system, aimed to record specific data from a significant number of patients with diabetes and documented stable CAD (SCAD). Methods and results: We conducted our survey across the country, in private and public primary, secondary, and tertiary care centers. A total of 1900 patients aged 71 ± 10 years old who suffered from both DM and chronic coronary syndromes were registered. Of the patients registered, 574 (30.24%) were women. It was found that 506 (26.6%) of the 1900 surveyed patients showed typical angina symptoms, while another 560 (29.5%) patients had developed angina-equivalent symptoms according to their history. Additionally, 324 (17%) patients had atypical symptoms that could not easily be attributed to existing CAD and the remaining 510 (26.8%) of the 1900 patients did not exhibit any angina symptoms during their daily activities. Functional testing for myocardial ischemia was not performed in 833 patients (43.8%). Myocardial scintigraphy was the most commonly used noninvasive technique (644 patients, 34%), while 492 patients (25.9%) had an exercise test and 159 (8.4%) underwent stress echocardiography. Conclusion: Real-world data in this specific high-risk population of diabetic patients with SCAD offer the opportunity to identify and improve diagnostic and therapeutic practice in the healthcare system of a European Union country.

Published
2021
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2. Clinical characteristics and management of patients with diabetes mellitus and stable coronary artery disease in daily clinical practice. The SCAD-DM Registry

Author

Evaggelos Pisimisis, Alexandros Amaslidis, Maria Samartzi, Christos Nikopoulos, Alexandros Vassilopoulos, Eleftherios Adamopoulos, Leonidas Lillis, Nikolaos Kipouridis, Emmanouil Chorozopoulos, Vasileios Drakoulidis, Christos Liatas, Georgia Vlahou, Emmanouil Psathakis, Konstantinos Kapetanios, Dimitrios Markou, Emmanouil Liodakis, Marios Konstantinou, Christos Athanasiou, Panos E. Vardas, Loukas Sinos, Vasileios Vogas, Paraskevi Psarogianni, Georgios I Papaioannou, Evangelos Rosmarakis, Chrysanthi Koukosi, Georgios Askar, Panagiotis Mavraganis, Konstantinos Panagiotopoulos, Ioannis Mavrodimitrakis, Soultana Papanastasiou, Nikolaos Kouvelas, Andreas Skanavis, Vasileios Vachliotis, Fotios Patsourakos, Spiridon Petrogiannis, Nikolaos Pontikakis, Dimitrios Mitropoulos, Stylianos Lambropoulos, Panagiotis Poulikarakos, Kristalenia Kafkala, Anestis Matziridis, Dimitrios Savvalas, Emmanouil Stefanakis, Isidoros Sarris, Andreas Papamichail, Nikolaos Marinakis, Virginia Markou, Konstantinos Koutras, Christos Katsikas, Mihail Kouremetis, Dimitrios I. Fotiadis, Vasileios Zouganelis, Ilias Antoniou, Savvas Nikiforos, Christos Kouris, Athanasios Karanasios, Andreas Pittaras, Emmanouel P. Vardas, Charalampos Albanis, Vasileios Mavridis, Theodora Tsiotika, Ioannis Tsiantis, Georgios Kontoroupis, Christos Hatjielefteriou, Nikolaos Kampouridis, Evropia Voukelatou, Grigorios Limperatos, Nikolaos Chrysomallis, Christos Stefopoulos, Kallinikos Tsakonas, Themistoklis Konstantinou, Nikiforos Vrettos, Achilleas Skordas, Ioannis Pantelakis, Harikleia Krontira, Eirini Kokani, Charalampos Parissis, George Hahalis, David Simeonidis, Konstantinos Vardakis, Georgios Pechlivanidis, Ioannis Vakalis, Maria Riga, Nikoloaos Oikonomidis, Alexandros Patsilinakos, Ioannis Mantas, Georgios Hondrokoukis, Apostolos Papadopoulos, Georgios Panagoulias, Vassiliki Sklirou, Konstantinos Davos, Theodoros Karonis, Stylianos Tzeis, Sokratis Avlonitis Antonios Beroukas, Konstantinos Katsas, Apostolos Kotidis, Vasileios Arfaras, Ioannis Goupios, Christos Zafiris, Maria Lolaka, Georgios Migias, Konstantinos Lalenis, Christos Harbas, Panagiotis Kalaras, Fotios Papalisandrou, Markos Prionidis, Dionisios Xenos, Maria E. Marketou, Konstantinos Svolis, Georgios Mablekos, Stavros Liropoulos, Georgios Tzeltzes, Ali Risgits, Dimitrios Sratech, Ilias Konstantinidis, Tsilla Zafiriou, Nikolaos Tsamis, Georgios Afaras, Christos Stathopoulos, Konstantinos Toulis, Evangelos Pisimisis, Georgios Kontopoulos, Maria Zaharia, Vasileios Hatjiioakeimidis, Antonios Giakoumis, Athanasios Patialiakas, Fanourios Zampetakis, Vasileios Karasavvidis, Vasileios Dimopoulos, Vassiliki Dimitroula, Antonios Manousakis, Christos Katsaris, Dimitrios Stergiou, Nikolaos Dimoulis, Kiriaki Faka, Georgios Koroniotis, Christos Stavrotheodoros, Panagiotis Papas, Konstantinos Zagoridis, Konstantinos Stefanis, Georgios Kolios, Iason Skotiniotis, Dimitrios Logothetis, Marina Kanakaraki, Achilleas Papadopoulos, Georgios Loukidelis, Vasileios Papavasileiou, Antonios Sideris, Konstantinos Aronis, Alexandros Galapis, Georgios Kouskos, Eftichia Demerouti, Vasileios Nikolaidis, Maria Andreopoulou, Anastasios Spanos, Konstantinos Sassalos, Eleni Tzamtzi-Mastaka, Charalambos Vlachopoulos, Georgios Karakostas, Georgios Koutsibanis, Nikolaos Smirnioudis, Georgios Siliogas, Sotirios Plastiras, Eleftherios Papavasileiou, Ioannis Livaditis, Andreas Karydakis, Ilias Apostolou, Emmanouil Scoubourdis, Sokratis Kazantzidis, Anna Panou, Rafail Stavropoulos, Dimitrios Psirropoulos, Georgios Aggelopoulos, Athanasios Platis, and Christos Mitroulas

Subjects
medicine.medical_specialty, Activities of daily living, Population, Myocardial Ischemia, Coronary Artery Disease, 030204 cardiovascular system & hematology, Coronary Angiography, Angina Pectoris, angina, Coronary artery disease, Angina, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Stress Echocardiography, Diabetes Mellitus, Diseases of the circulatory (Cardiovascular) system, Medicine, media_common.cataloged_instance, Humans, 030212 general & internal medicine, Registries, European union, education, media_common, Aged, Aged, 80 and over, education.field_of_study, business.industry, Middle Aged, medicine.disease, RC666-701, Female, Cardiology and Cardiovascular Medicine, business, Scad
Abstract

Background Patients with diabetes mellitus and coronary artery disease (CAD) represent a high-risk population, where comorbidities are common, and the progression of coronary heart disease is relatively rapid and extensive. The present survey, conducted nationwide in a Eurozone country, Greece, with a properly organized national health system, aimed to record specific data from a significant number of patients with diabetes and documented stable CAD (SCAD). Methods and Results We conducted our survey across the country, in private and public primary, secondary and tertiary care centers. A total of 1900 patients aged 71±10 years old suffering from both diabetes mellitus and chronic coronary syndromes were registered. Of the patients registered 574 (30.24%) were women. It was found that 506 (26.6%) of the 1900 surveyed patients showed typical angina symptoms, while another 560 (29.5%) patients had developed angina-equivalent symptoms according to their history. Additionally, 324 (17%) patients had atypical symptoms that could not easily be attributed to existing coronary artery disease and the remaining 510 (26.8%) of the 1900 patients did not exhibit any angina symptoms during their daily activities. Functional testing for myocardial ischemia was not performed in 833 patients (43.8%). Myocardial scintigraphy was the most commonly used noninvasive technique (644 patients, 34%), while 492 patients (25.9%) had an exercise test and 159 (8.4%) underwent stress echocardiography. Conclusion Real world data in this specific high-risk population of diabetic patients with SCAD offers the opportunity to identify and improve diagnostic and therapeutic practice in the health-care system of a European Union country.

Published
2020

3. Development of the Greek Verbal Learning Test: reliability, construct validity, and normative standards

Author

Maria Giannakou, Stella Tsotsi, A. Dardagani, Mary H. Kosmidis, Christina H. Vlahou, Nikolaos Pontikakis, Emmanuel Zervoudakis, and Aikaterini Giazkoulidou

Subjects
Adult, Male, Adolescent, education, Sample (statistics), Neuropsychological Tests, Verbal learning, Sensitivity and Specificity, Developmental psychology, Young Adult, Reference Values, Residence Characteristics, Orientation, Reaction Time, Humans, Aged, Aged, 80 and over, Analysis of Variance, California Verbal Learning Test, Greece, Learning Disabilities, Age Factors, Construct validity, Reproducibility of Results, Regression analysis, General Medicine, Middle Aged, Verbal Learning, humanities, Regression, Test (assessment), Psychiatry and Mental health, Clinical Psychology, Neuropsychology and Physiological Psychology, Brain Injuries, Schizophrenia, Normative, Regression Analysis, Female, Psychology
Abstract

We developed a multiple-form list learning test appropriate for use with the Greek population and generated norms for clinical and research use. This task, the Greek Verbal Learning Test (GVLT), was based on the California Verbal Learning Test. We administered the standard version (Form A) to a sample of 354 healthy individuals, as well as two alternative forms (B and C) to a subgroup of the initial sample. Performance on the three forms was equivalent, and each test presented excellent internal consistency. We found good sensitivity and specificity in the testas (Form A) utility in differentiating individuals with schizophrenia (n = 50) and individuals with traumatic brain injury (n = 53) from healthy adults. A multiple regression analysis indicated that age, education and sex predicted performance. Regression-based norms are also provided. Taken together, these data provide preliminary support for the reliability and construct validity of the GVLT.

Published
2012

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