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413 results on '"Nir Hacohen"'

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1. The commitment of the human cell atlas to humanity

2. Cryoablation and post-progression immune checkpoint inhibition in metastatic melanoma: a phase II trial

3. SARS-CoV-2 infection elucidates features of pregnancy-specific immunity

4. 1002 Single cell transcriptomics in kidney tissue from African American patients enrolled in the accelerating medicines partnership (AMP) implicates tubular cells in the pathogenesis of APOL1 associated lupus nephritis

5. 1012 Deep peripheral blood immunophenotyping identifies a subgroup of lupus nephritis patients characterized by high type 1 interferon signaling, persistent activated immune cells and poor renal response to standard of care at 1 year

6. 1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA/SLE consortium

7. The HLA-II immunopeptidome of SARS-CoV-2

8. 628 Circulatory plasma proteomic biomarkers combined with high-throughput proteomic screen of patient-derived organotypic tumor spheroids predict responses to immunotherapy in melanoma patients

9. 1255 Single cell dissection of human checkpoint inhibitor hepatitis reveals insights into liver immune tolerance

12. 561 Targeting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

13. Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade

14. ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling

15. LO-006 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritis better than proteinuria

16. Protocol for bulk RNA sequencing of enriched human neutrophils from whole blood and estimation of sample purity

17. 1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortium

18. 1112 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritisbetter than proteinuria

19. A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies

20. The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

21. Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

22. MAUDE: inferring expression changes in sorting-based CRISPR screens

23. Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

24. Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

29. Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network

30. Immune receptor repertoires in pediatric and adult acute myeloid leukemia

31. Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions

32. SLAMF6​ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

33. Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

34. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

35. Resistance to checkpoint blockade therapy through inactivation of antigen presentation

36. An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling

37. Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

38. The Human Cell Atlas

39. Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy

40. Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

41. The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection.

42. TGF-β suppresses β-catenin-dependent tolerogenic activation program in dendritic cells.

43. An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion.

44. Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells.

46. Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

47. Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial

48. Targeting TBK1 to overcome resistance to cancer immunotherapy

49. Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients

50. A genome-wide optical pooled screen reveals regulators of cellular antiviral responses

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