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1. Concordance in the estimation of tumor percentage in non-small cell lung cancer using digital pathology

Author

Carretero-Barrio, Irene, Pijuan, Lara, Illarramendi, Adrián, Curto, Daniel, López-Ríos, Fernando, Estébanez-Gallo, Ángel, Castellvi, Josep, Granados-Aparici, Sofía, Compañ-Quilis, Desamparados, Noguera, Rosa, Esteban-Rodríguez, Isabel, Sánchez-Güerri, Ignacio, Ramos-Guerra, Ana Delia, Ortuño, Juan Enrique, Garrido, Pilar, Ledesma-Carbayo, María Jesús, Benito, Amparo, and Palacios, José

Published
2024
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4. Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup

Author

Martinez-Monleon, Angela, Kryh Öberg, Hanna, Gaarder, Jennie, Berbegall, Ana P., Javanmardi, Niloufar, Djos, Anna, Ussowicz, Marek, Taschner-Mandl, Sabine, Ambros, Inge M., Øra, Ingrid, Sandstedt, Bengt, Beiske, Klaus, Ladenstein, Ruth, Noguera, Rosa, Ambros, Peter F., Gordon Murkes, Lena, Ljungman, Gustaf, Kogner, Per, Fransson, Susanne, and Martinsson, Tommy

Published
2022
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5. Blended-Learning Experiences in the Elective Course 'Scientific Writing'

Author

Pérez Pino, María Teresa, Casar Espino, Liliana Argelia, Basabe, Leonid Rodríguez, Granda Dihigo, Ailec, Bravo, Tito Díaz, González Noguera, Rosa Adela, Castro Álvarez, Pedro, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Auer, Michael E., editor, and May, Dominik, editor

Published
2021
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8. Characterization of Vitronectin Effect in 3D Ewing Sarcoma Models: A Digital Microscopic Analysis of Two Cell Lines.

Author

López-Carrasco, Amparo, Parra-Haro, Karina, Vieco-Martí, Isaac, Granados-Aparici, Sofía, Díaz-Martín, Juan, Salguero-Aranda, Carmen, Acevedo-León, Delia, de Álava, Enrique, Navarro, Samuel, and Noguera, Rosa

Subjects
VIRTUAL microscopy, CANCER invasiveness, CLUSTER analysis (Statistics), TUMORS in children, RESEARCH funding, ENZYME-linked immunosorbent assay, GLYCOPROTEINS, TUMOR markers, BODY fluid examination, CELL lines, CELL culture, SECRETION, EWING'S sarcoma, EXTRACELLULAR matrix, THREE-dimensional printing, COMPARATIVE studies, METABOLOMICS, PHENOTYPES
Abstract

Simple Summary: Three-dimensional (3D) models enable simplified and controlled in vitro replication of tumor microenvironment features, making them easier to study. In the current work, we developed 3D hydrogels based on gelatin plus silk fibroin with tunable mechanical properties, incorporating vitronectin (a glycoprotein related to tumor aggressiveness) into the scaffolds. Digital analysis was applied to monitor Ewing sarcoma cell line growth and morphology in response to the 3D model composition and different culture times, opening the possibility of its use to study other proteins of interest and tumor types. Our findings highlight the heterogeneity of cell line responses to their microenvironment, underscoring the enormous potential of these hydrogels as mechanodrug-testing platforms and for studying cell protein secretion as an initial step in liquid biopsy biomarker research. Ewing sarcoma (ES) is an aggressive bone and soft-tissue pediatric cancer. High vitronectin (VN) expression has been associated with poor prognosis in other cancers, and we aimed to determine the utility of this extracellular matrix glycoprotein as a biomarker of aggressiveness in ES. Silk fibroin plus gelatin–tyramine hydrogels (HGs) were fabricated with and without cross-linked VN and cultivated with A673 and PDX73 ES cell lines for two and three weeks. VN secretion to culture media was assessed using ELISA. Morphometric analysis was applied for phenotypic characterization. VN release to culture media was higher in 3D models than in monolayer cultures, and intracellular, intercellular, and pericluster presence was also observed. A673-HGs showed lower density of clusters but a proportion of larger clusters than PDX73-HGs, which presented low cluster circularity. The cluster density of A673-HGs without added VN was higher than with added VN and slightly lower in the case of PDX73-HGs. Furthermore, a culture time of three weeks provided no benefits in cluster growth compared to two weeks, especially in A673-HGs. These advances in 3D modeling and digital quantification pave the way for future studies in ES and other cancers to deepen understanding about intra- and intercellular heterogeneity and anti-adhesion VN therapies. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?

Author

López-Carrasco, Amparo, Vieco-Martí, Isaac, Granados-Aparici, Sofía, Acevedo-León, Delia, Estañ-Capell, Nuria, Portugal, Raquel, Huerta-Aragonés, Jorge, Cañete, Adela, Navarro, Samuel, and Noguera, Rosa

Subjects
VITRONECTIN, CHILDHOOD cancer, EXTRACELLULAR matrix, RECEIVER operating characteristic curves, CELL migration, CANCER cell culture
Abstract

Vitronectin is a glycoprotein present in plasma and the extracellular matrix that is implicated in cell migration. The high amount of vitronectin found in neuroblastoma biopsies has been associated with poor prognosis. Moreover, increased vitronectin levels have been described in the plasma of patients with different cancers. Our aim was to assess vitronectin as a potential circulating biomarker of neuroblastoma prognosis. Vitronectin concentration was quantified using ELISA in culture media of four neuroblastoma cell lines grown in a monolayer and in 3D models, and in the plasma of 114 neuroblastoma patients. Three of the neuroblastoma cell lines secreted vitronectin to culture media when cultured in a monolayer and 3D models. Vitronectin release was higher by neuroblastoma cells cultured in 3D models than in the monolayer and was still elevated when cells were grown in 3D scaffolds with cross-linked vitronectin. Vitronectin secretion occurred independently of cell numbers in cultures. Its concentration in the plasma of neuroblastoma patients ranged between 52.4 and 870 µg/mL (median, 218 µg/mL). A ROC curve was used to establish a cutoff of 361 µg/mL, above which patients over 18 months old had worse prognosis (p = 0.0018). Vitronectin could be considered a new plasma prognostic biomarker in neuroblastoma and warrants confirmation in collaborative studies. Drugs inhibiting vitronectin interactions with cells and/or the extracellular matrix could represent a significant improvement in survival for neuroblastoma patients. [ABSTRACT FROM AUTHOR]

Published
2024
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10. 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma

Author

Siaw, Joachim Tetteh, Javanmardi, Niloufar, Van den Eynden, Jimmy, Lind, Dan Emil, Fransson, Susanne, Martinez-Monleon, Angela, Djos, Anna, Sjöberg, Rose-Marie, Östensson, Malin, Carén, Helena, Trøen, Gunhild, Beiske, Klaus, Berbegall, Ana P., Noguera, Rosa, Lai, Wei-Yun, Kogner, Per, Palmer, Ruth H., Hallberg, Bengt, and Martinsson, Tommy

Published
2020
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19. Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study

Author

Berbegall, Ana P., Bogen, Dominik, Pötschger, Ulrike, Beiske, Klaus, Bown, Nick, Combaret, Valérie, Defferrari, Raffaella, Jeison, Marta, Mazzocco, Katia, Varesio, Luigi, Vicha, Ales, Ash, Shifra, Castel, Victoria, Coze, Carole, Ladenstein, Ruth, Owens, Cormac, Papadakis, Vassilios, Ruud, Ellen, Amann, Gabriele, Sementa, Angela R., Navarro, Samuel, Ambros, Peter F., Noguera, Rosa, and Ambros, Inge M.

Published
2018
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25. Supplementary Table 2 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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26. Figure S2 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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27. Supplementary table 6-7 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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28. Supplementary Data 1 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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29. Data from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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30. Supplementary Methods from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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31. Supplementary Table 3 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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32. Supplementary Table 1 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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33. Supplementary Figure 1, Tables 1-3 from miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples

Author

De Preter, Katleen, primary, Mestdagh, Pieter, primary, Vermeulen, Joëlle, primary, Zeka, Fjoralba, primary, Naranjo, Arlene, primary, Bray, Isabella, primary, Castel, Victoria, primary, Chen, Caifu, primary, Drozynska, Elzbieta, primary, Eggert, Angelika, primary, Hogarty, Michael D., primary, Iżycka-Swieszewska, Ewa, primary, London, Wendy B., primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bryan, Kenneth, primary, Schowe, Benjamin, primary, van Sluis, Peter, primary, Molenaar, Jan J., primary, Schramm, Alexander, primary, Schulte, Johannes H., primary, Stallings, Raymond L., primary, Versteeg, Rogier, primary, Laureys, Geneviève, primary, Van Roy, Nadine, primary, Speleman, Frank, primary, and Vandesompele, Jo, primary

Published
2023
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34. Supplementary table 3-5 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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35. Supplementary Table 4 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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36. Supplementary Table 1 from Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

Author

De Brouwer, Sara, primary, De Preter, Katleen, primary, Kumps, Candy, primary, Zabrocki, Piotr, primary, Porcu, Michaël, primary, Westerhout, Ellen M., primary, Lakeman, Arjan, primary, Vandesompele, Jo, primary, Hoebeeck, Jasmien, primary, Van Maerken, Tom, primary, De Paepe, Anne, primary, Laureys, Geneviève, primary, Schulte, Johannes H., primary, Schramm, Alexander, primary, Van Den Broecke, Caroline, primary, Vermeulen, Joëlle, primary, Van Roy, Nadine, primary, Beiske, Klaus, primary, Renard, Marleen, primary, Noguera, Rosa, primary, Delattre, Olivier, primary, Janoueix-Lerosey, Isabelle, primary, Kogner, Per, primary, Martinsson, Tommy, primary, Nakagawara, Akira, primary, Ohira, Miki, primary, Caron, Huib, primary, Eggert, Angelika, primary, Cools, Jan, primary, Versteeg, Rogier, primary, and Speleman, Frank, primary

Published
2023
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37. Supplementary Figure 1 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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38. Supplementary table 8-14 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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40. Supplementary Table 2 from Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

Author

De Brouwer, Sara, primary, De Preter, Katleen, primary, Kumps, Candy, primary, Zabrocki, Piotr, primary, Porcu, Michaël, primary, Westerhout, Ellen M., primary, Lakeman, Arjan, primary, Vandesompele, Jo, primary, Hoebeeck, Jasmien, primary, Van Maerken, Tom, primary, De Paepe, Anne, primary, Laureys, Geneviève, primary, Schulte, Johannes H., primary, Schramm, Alexander, primary, Van Den Broecke, Caroline, primary, Vermeulen, Joëlle, primary, Van Roy, Nadine, primary, Beiske, Klaus, primary, Renard, Marleen, primary, Noguera, Rosa, primary, Delattre, Olivier, primary, Janoueix-Lerosey, Isabelle, primary, Kogner, Per, primary, Martinsson, Tommy, primary, Nakagawara, Akira, primary, Ohira, Miki, primary, Caron, Huib, primary, Eggert, Angelika, primary, Cools, Jan, primary, Versteeg, Rogier, primary, and Speleman, Frank, primary

Published
2023
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41. Legends to Supplementaries from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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42. Supplementary Data 2 from Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Author

Oberthuer, André, primary, Juraeva, Dilafruz, primary, Hero, Barbara, primary, Volland, Ruth, primary, Sterz, Carolina, primary, Schmidt, Rene, primary, Faldum, Andreas, primary, Kahlert, Yvonne, primary, Engesser, Anne, primary, Asgharzadeh, Shahab, primary, Seeger, Robert, primary, Ohira, Miki, primary, Nakagawara, Akira, primary, Scaruffi, Paola, primary, Tonini, Gian Paolo, primary, Janoueix-Lerosey, Isabelle, primary, Delattre, Olivier, primary, Schleiermacher, Gudrun, primary, Vandesompele, Jo, primary, Speleman, Frank, primary, Noguera, Rosa, primary, Piqueras, Marta, primary, Bénard, Jean, primary, Valent, Alexander, primary, Avigad, Smadar, primary, Yaniv, Isaac, primary, Grundy, Richard G., primary, Ortmann, Monika, primary, Shao, Chunxuan, primary, Schwab, Manfred, primary, Eils, Roland, primary, Simon, Thorsten, primary, Theissen, Jessica, primary, Berthold, Frank, primary, Westermann, Frank, primary, Brors, Benedikt, primary, and Fischer, Matthias, primary

Published
2023
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43. Supplementary table 1-2 from Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Author

Braekeveldt, Noémie, primary, von Stedingk, Kristoffer, primary, Fransson, Susanne, primary, Martinez-Monleon, Angela, primary, Lindgren, David, primary, Axelson, Håkan, primary, Levander, Fredrik, primary, Willforss, Jakob, primary, Hansson, Karin, primary, Øra, Ingrid, primary, Backman, Torbjörn, primary, Börjesson, Anna, primary, Beckman, Siv, primary, Esfandyari, Javanshir, primary, Berbegall, Ana P., primary, Noguera, Rosa, primary, Karlsson, Jenny, primary, Koster, Jan, primary, Martinsson, Tommy, primary, Gisselsson, David, primary, Påhlman, Sven, primary, and Bexell, Daniel, primary

Published
2023
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47. MOXD1 is a gate-keeper of organ homeostasis and functions as a tumor-suppressor in neuroblastoma

Author

Fredlund, Elina, primary, Andersson, Stina, additional, Hilgert, Elien, additional, Álvarez-Hernán, Guadalupe, additional, Monferrer, Ezequiel, additional, Karakaya, Sinan, additional, Gregor, Tomas, additional, Loontiens, Siebe, additional, Bek, Jan Willem, additional, Lecomte, Estelle, additional, Magnusson, Emma, additional, Miltenyte, Enrika, additional, Cabirol, Marie, additional, Kyknas, Michail, additional, Engström, Niklas, additional, Henriksson, Marie Arsenian, additional, Hammarlund, Emma, additional, Noguera, Rosa, additional, Speleman, Frank, additional, van Nes, Johan, additional, and Mohlin, Sofie, additional

Published
2023
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48. MOXD1 Is a Gate-Keeper of Organ Homeostasis and Functions as a Tumor Suppressor

Author

Fredlund, Elina, primary, Andersson, Stina, additional, Hilgert, Elien, additional, Alvares Hernan, Guadalupe, additional, Monferrer, Ezequiel, additional, Karakaya, Sinan, additional, Gregor, Tomas, additional, Loontiens, Siebe, additional, Bek, Jan Willem, additional, Lecomte, Estelle, additional, Magnusson, Emma, additional, Miltenyte, Enrika, additional, Cabirol, Marie, additional, Kyknas, Michail, additional, Engström, Niklas, additional, Arsenain-Henriksson, Marie, additional, Hammarlund, Emma, additional, Noguera, Rosa, additional, Speleman, Frank, additional, van Nes, Johan, additional, and Mohlin, Sofie, additional

Published
2023
Full Text
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49. Integrating digital pathology with transcriptomic and epigenomic tools for predicting metastatic uterine tumor aggressiveness

Author

Sonzini, Giorgia, primary, Granados-Aparici, Sofia, additional, Sanegre, Sabina, additional, Diaz-Lagares, Angel, additional, Diaz-Martin, Juan, additional, de Andrea, Carlos, additional, Eritja, Núria, additional, Bao-Caamano, Aida, additional, Costa-Fraga, Nicolás, additional, García-Ros, David, additional, Salguero-Aranda, Carmen, additional, Davidson, Ben, additional, López-López, Rafael, additional, Melero, Ignacio, additional, Navarro, Samuel, additional, Ramon y Cajal, Santiago, additional, de Alava, Enrique, additional, Matias-Guiu, Xavier, additional, and Noguera, Rosa, additional

Published
2022
Full Text
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