Search

Your search keyword '"Noize, Pernelle"' showing total 232 results
Start Over Author "Noize, Pernelle"
232 results on '"Noize, Pernelle"'

8. REview of potentially inappropriate MEDIcation pr[e]scribing in Seniors (REMEDI[e]S): French implicit and explicit criteria

Author

Roux, Barbara, Berthou-Contreras, Julie, Beuscart, Jean-Baptiste, Charenton-Blavignac, Marion, Doucet, Jean, Fournier, Jean-Pascal, de la Gastine, Blandine, Gautier, Sophie, Gonthier, Régis, Gras, Valérie, Grau, Muriel, Noize, Pernelle, Polard, Elisabeth, Rudelle, Karen, Valnet-Rabier, Marie-Blanche, Tannou, Thomas, and Laroche, Marie-Laure

Published
2021
Full Text
View/download PDF

11. Patterns of Use, Safety, and Effectiveness of Targeted Therapies in First-Line Treatment of Metastatic Colorectal Cancer According to Age: The STROMBOLI Cohort Study

Author

Smith, D., Tubiana-Mathieu, N., Michel, P., Guimbaud, R., Becouarn, Y., Viret, F., Larregain-Fournier, D., Botreau, Y., Texereau, P., Auby, D., Gautier-Felizot, L., Loury-Larivière, I., Brudieux, E., Cany, L., Lecaille, C., Jaubert, D., Guichard, P., Bernard, O., Vives, L., Taoubi, N., Martinez, M., Burki, F., Roque, I., Thouveny, F., Gaspard, M.H., Gouverneur, Amandine, Coutureau, Juliette, Jové, Jérémy, Rouyer, Magali, Grelaud, Angela, Duc, Sophie, Gérard, Stéphane, Smith, Denis, Ravaud, Alain, Droz, Cécile, Bernard, Marie-Agnès, Lassalle, Régis, Forrier-Réglat, Annie, and Noize, Pernelle

Published
2019
Full Text
View/download PDF

22. Secondary Metastases Resection After Bevacizumab Plus Irinotecan-Based Chemotherapy in First-Line Therapy of Metastatic Colorectal Cancer in a Real-Life Setting: Results of the ETNA Cohort

Author

Rouyer, Magali, Smith, Denis, Laurent, Christophe, Becouarn, Yves, Guimbaud, Rosine, Michel, Pierre, Tubiana-Mathieu, Nicole, Balestra, Aurélie, Jové, Jérémy, Robinson, Philip, Noize, Pernelle, Moore, Nicholas, Ravaud, Alain, Fourrier-Réglat, Annie, and on behalf of the ETNA study group

Published
2016
Full Text
View/download PDF

24. Real‐life patterns of use, safety and effectiveness of sunitinib in first‐line therapy of metastatic renal cell carcinoma: the SANTORIN cohort study

Author

Noize, Pernelle, Grelaud, Angela, Bay, Jacques‐Olivier, Chevreau, Christine, Gross‐Goupil, Marine, Culine, Stéphane, Ferrière, Jean‐Marie, Moulin, Flore, Robinson, Philip, Balestra, Aurelie, Lamarque, Stéphanie, Bernard, Marie‐Agnès, Lassalle, Régis, Rouyer, Magali, Droz‐Perroteau, Cécile, Moore, Nicholas, Fourrier‐Réglat, Annie, and Ravaud, Alain

Published
2017
Full Text
View/download PDF

28. Incidence of heart failure following exposure to a protein kinase inhibitor, a French population-based study.

Author

Zelmat, Yoann, Conte, Cécile, Noize, Pernelle, Vabre, Clémentine, Pajiep, Marie, Lafaurie, Margaux, Lapeyre-Mestre, Maryse, and Despas, Fabien

Subjects
PROTEIN kinase inhibitors, HEART failure, DRUG side effects, NEPRILYSIN, VEMURAFENIB, DASATINIB
Abstract

Aims: Pharmacovigilance signals of heart failure (HF) following exposure to protein kinase inhibitors (PKIs) have been detected in recent years. Our aim was to identify the PKIs most frequently associated with the development of HF. Methods: Using the French National Healthcare Database, all patients newly exposed to a PKI between January 2011 and June 2014 were followed up for 18 months. Specific hospitalization diagnosis and long-term HF-related disease codes were used to identify HF patients. HF incidence rate ratios (IRRs) were measured and adjusted hazard ratios (aHRs) were estimated using a Cox model. Sensitivity analyses were performed to limit the potential indication and competitive risk bias. Results: Thirteen PKIs were studied. Among the 49 714 new PKI users registered during the study period, the mean IRR of HF was 3.38 per 100 person-years, with a median time to onset of 155 days. We found a significant increase in the incidence of HF for six medicinal products: pazopanib (aHR = 2.42, 95% confidence interval [CI] 1.67-3.52), dasatinib (aHR = 2.22, 95% CI 1.42-3.44), ruxolitinib (aHR = 2.11, 95% CI 1.69-2.64), crizotinib (aHR = 1.71, 95% CI 1.07-2.72), everolimus (aHR = 1.45, 95% CI 1.26-1.67) and vemurafenib (aHR = 1.37, 95% CI 1.01-1.86). Sensitivity analyses were consistent with our primary analysis. Conclusions: The current study provides knowledge on HF following exposure to a PKI. Additional studies could confirm these results for dasatinib, everolimus, pazopanib and ruxolitinib, and particularly for the two medicinal products with results slightly above the significance threshold, namely, crizotinib and vemurafenib, in our sensitivity analyses. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

30. Targeted Therapy for Older Patients with Non-Small Cell Lung Cancer: Systematic Review and Guidelines from the French Society of Geriatric Oncology (SoFOG) and the French-Language Society of Pulmonology (SPLF)/French-Language Oncology Group (GOLF)

Author

Greillier, Laurent, primary, Gauvrit, Manon, additional, Paillaud, Elena, additional, Girard, Nicolas, additional, Montégut, Coline, additional, Boulahssass, Rabia, additional, Wislez, Marie, additional, Pamoukdjian, Frédéric, additional, Corre, Romain, additional, Cabart, Mathilde, additional, Caillet, Philippe, additional, Belaroussi, Yaniss, additional, Frasca, Matthieu, additional, Noize, Pernelle, additional, Wang, Pascal, additional, Mebarki, Soraya, additional, Mathoulin-Pelissier, Simone, additional, and Couderc, Anne-Laure, additional

Published
2022
Full Text
View/download PDF

38. Br J Clin Pharmacol

Author

CASAROTTO, Emilie, Noize, Pernelle, Letinier, Louis, SALVO, Francesco, Pham-Ledard, Anne, Molimard, Mathieu, Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Abstract

We described the safety profiles of all drug classes used for the treatment of advanced melanoma from the United States Food and Drug Administration Adverse Event Reporting System over the period 2008 to 2018. Adverse reactions reported in 25,900 pharmacovigilance cases were described for chemotherapies, immunomodulators, targeted therapies, and immunotherapies. There was a sharp increase in the number of cases over time, with peaks associated with the launch of new treatments. The adverse reactions diversified over time; notably, skin (alopecias, dermatitis) and retinal disorders were frequently associated with targeted therapies and endocrine disorders (hypothalamus, thyroid and adrenal dysfunctions) with immunotherapies. Less well-known reactions were also detected, such as neuropsychiatric disorders with targeted therapies and gastrointestinal ulcers, pneumothorax, and pleural effusions with immunotherapies. The findings highlight the need for various health professionals (including medical specialists or trained nurses) to enhance management of complications.

Published
2020
Full Text
View/download PDF

39. Medicine misuse: A systematic review and proposed hierarchical terminology

Author

Singier, Allison, Noize, Pernelle, Berdai, D., Daveluy, Amelie, Arnaud, Mickael, Molimard, Mathieu, Begaud, Bernard, Salvo, Francesco, Admin, Oskar, Bordeaux population health (BPH), and Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Abstract

AIMS: Although medicine misuse is a public health issue, it has multiple meanings in the medical literature. This study aimed to characterize, classify and identify the most appropriate definitions of medicine misuse. METHODS: A systematic review was performed in Medline, ISI Web of Science, SocINDEX, PsycInfo, PsycArticles and Psychological and Behavioral Sciences Collection, using keywords related to "misuse", "appropriateness" and "medicine" between 1 November 2008 and 25 August 2020. Additional searches were conducted in websites of regulatory agencies and public health institutions. Two authors independently selected studies providing both definitions and examples of misuse, while a third resolved disagreements. Definitions were used to propose a hierarchical classification based on initiator, intent, purpose and context of medicine misuse. The study is registered on PROSPERO: CRD42018115789. RESULTS: Of 3404 identified records, 51 were included. A total of 71 definitions and 74 examples of misuse were retrieved. When the prescriber is initiator and according to intent, potential medicine misuse referred to "intentional or unintentional prescribing not in line with clinical evidence". Based on context, they could prescribe medicines not clinically justified, i.e. overprescribing, or prescribe indicated medicines incorrectly, i.e. misprescribing. Among other groups of definitions, those overlapping with drug abuse or medication use errors were considered out-of-scope. CONCLUSION: This systematic review provides a comprehensive overview of the terms and definitions used to characterize medicine misuse and could serve as a basis for a terminology that makes clear distinctions between misuse, abuse and errors.

Published
2020
Full Text
View/download PDF

41. Prevalence and direct costs of potentially inappropriate prescriptions in France: a population-based study.

Author

Roux, Barbara, Bezin, Julien, Morival, Camille, Noize, Pernelle, and Laroche, Marie-Laure

Abstract

Potentially inappropriate prescriptions (PIPs) in the older population remain a growing public health concern due to the many associated adverse events increasing healthcare service use and health costs. This study aimed to assess the prevalence and direct costs of PIPs in older adults aged ≥65 years in France. A population-based cross-sectional study was conducted in 2017 using a representative sample of the French national healthcare reimbursement system database. PIPs were defined using the French REMEDI[e]S tool. Overall reimbursed direct costs and by PIP category were extrapolated to the French older population. The overall PIP prevalence was estimated at 56.7% (95% CI: 56.4–57.0). Medications with an unfavorable benefit/risk ratio had the highest prevalence (34.0%, 95% CI: 33.7–34.3). Direct costs associated with PIPs represented 6.3% of the total reimbursed medication costs in 2017 (€507 million). Drug duplications were the main contributors to these costs (39.2% of the total reimbursed PIP costs, €199 million) and among all PIPs, proton pump inhibitors (>8 weeks) were the most expensive PIPs (€152 million). PIP prevalence is still high among French older adults, with substantial direct costs. Large-scale interventions targeting the most prevalent and/or costly PIPs are needed to reduce their clinical and economic impacts. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

42. Adverse drug reactions induced by cotrimoxazole: Still a lot of preventable harm.

Author

Coppry, Maïder, Duret, Stéphanie, Berdaï, Driss, Miremont‐Salamé, Ghada, Fourrier‐Réglat, Annie, Haramburu, Françoise, Rogues, Anne‐Marie, and Noize, Pernelle

Subjects
DRUG side effects, CO-trimoxazole, INAPPROPRIATE prescribing (Medicine), BLOOD diseases, PRODUCT attributes
Abstract

Owing to a broad spectrum and low cost antimicrobial, cotrimoxazole is largely prescribed. However, its use is associated with various adverse drug reactions (ADRs) that warrant to ensure rational prescribing. This study aimed to describe spontaneous reports of cotrimoxazole ADRs and to evaluate the quality of prescription in patients who had ADRs. Suspected cotrimoxazole‐induced ADRs cases reported to the Bordeaux regional pharmacovigilance center (France) during a 5‐year period were described. Seriousness was assessed according to international criteria. Quality of prescription was assessed by compliance with the Summary of Product Characteristics (SPC) and relevance of cotrimoxazole indication. Then, an ADR was considered as preventable if the cotrimoxazole indication was not relevant, or potentially preventable if indication was relevant but the prescription was not compliant with the SPC. A total of 96 cases were analyzed: median age was 60.5 years (range: 4–94); 59.4% of patients were male. ADRs were mostly cutaneous disorders (n = 46) and hematological disorders (n = 25). A total of 60 serious ADRs occurred in 55 patients. Prescribers complied with all SPC recommendations in 21.9% of cases. Indication of cotrimoxazole was relevant or highly relevant in 41 cases. In 58% of cases, the occurrence of a cotrimoxazole‐induced ADR would have been preventable or potentially preventable. In a context of increasing interest for this antibiotic to treat infections due to resistant bacteria, physicians should be more aware of the potential consequences of inappropriate prescribing cotrimoxazole and reserve its use when there is no alternative and under suitable monitoring. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

46. Effectiveness of first‐line cetuximab in wild‐type RAS metastatic colorectal cancer according to tumour BRAF mutation status from the EREBUS cohort

Author

Rouyer, Magali, primary, François, Eric, additional, Sa Cunha, Antonio, additional, Monnereau, Alain, additional, Bignon, Emmanuelle, additional, Jové, Jérémy, additional, Lassalle, Régis, additional, Droz‐Perroteau, Cécile, additional, Moore, Nicholas, additional, Noize, Pernelle, additional, Fourrier‐Réglat, Annie, additional, and Smith, Denis, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results