28 results on '"Ntouroupi, T."'
Search Results
2. Dietary patterns and lifestyle characteristics in adults: results from the Hellenic National Nutrition and Health Survey (HNNHS)
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Fappa, E., Theodoraki, E.-M., Trichia, E., Sialvera, T.-E., Varytimiadi, A., Spyreli, E., Koutelidakis, A., Karlis, G., Zacharia, S., Papageorgiou, A., Chrousos, G.P., Dedoussis, G., Dimitriadis, G., Manios, I., Roma, E., Karageorgou, D., Magriplis, E., Mitsopoulou, A.V., Dimakopoulos, I., Bakogianni, I., Micha, R., Michas, G., Chourdakis, M., Ntouroupi, T., Tsaniklidou, S.M., Argyri, K., Panagiotakos, D.B., and Zampelas, A.
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- 2019
- Full Text
- View/download PDF
3. Prevalence of type 2 diabetes mellitus in a representative sample of Greek adults and its association with modifiable risk factors: results from the Hellenic National Nutrition and Health Survey
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Magriplis, E. Panagiotakos, D. Papakonstantinou, E. and Mitsopoulou, V, A- Karageorgou, D. Dimakopoulos, I and Bakogianni, I Chourdakis, M. Micha, R. Michas, G. and Ntouroupi, T. Tsaniklidou, S-M Argyri, K. Dimitriadis, G. and Zampelas, A. Contributors Advisory Comm
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endocrine system diseases ,nutritional and metabolic diseases - Abstract
Objective: Diabetes mellitus is a disease associated with many complications leading to premature death. The aim of this study was to estimate prevalence of type 2 diabetes (T2D), and the proportion of the population unaware of the condition, in association with modifiable risk factors. Study design: Data from the Hellenic National Nutrition and Health Survey were used (n = 3773 adults, 40.8% men) and were obtained by trained personnel. Methods: Diabetes mellitus disease status was categorized as per the International Classification of Diseases codes (10th version). A subsample from the two main metropolitan areas was used to assess T2D and impaired fasting glucose (IFG) (n = 990; 38.2% men) from plasma analysis. Results: The prevalence of T2D in the population was 5.2% in total, reaching 13.7% in adults aged >60 years (no sex differences). IFG was observed in 27.3% of adults in the two metropolitan areas, and 40% were unaware of having T2D in this subsample. The likelihood of having T2D significantly increased with age and body weight, whereas it decreased with higher educational level and physical activity (P for all
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- 2021
4. Micronutrient dietary intakes and their food sources in adults: the Hellenic National Nutrition and Health Survey (HNNHS)
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Mitsopoulou, A.V. Magriplis, E. Michas, G. Micha, R. Chourdakis, M. Chrousos, G.P. Roma, E. Panagiotakos, D.B. Zampelas, A. Karageorgou, D. Bakogianni, I. Dimakopoulos, I. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Dedoussis, G. Dimitriadis, G. Manios, I.
- Abstract
Background: The present study aimed to assess micronutrient intake among Greek adults and to identify the main food sources that contribute to it. Methods: Food consumption data from 2389 participants in the Hellenic National Nutrition and Health Survey (HNNHS), collected with 24-h recalls, was used to calculate micronutrient intakes. Usual nutrient intake was estimated according to the National Cancer Institute method. Nutrient adequacy was estimated using the estimated average requirement (EAR) cut-point method, when available, or adequate intake otherwise. The probability approach was used to determine iron intake adequacy in females of reproductive age. Food group contribution for each nutrient assessed was derived to identify their main food sources. Results: Almost all individuals had vitamin D intake below EAR, whereas vitamins A, E, K and C, as well as potassium intake, were also insufficient in a considerable percentage of the population (>70% in most age groups). Calcium intake was substantially below the EAR for females aged >50 years and males >70 years; the same for magnesium in males >70 years. Furthermore, 50% of females, including those of reproductive age, had intake of folate below EAR. More than 50% of the population (to 79%) exceeded the upper tolerable limit for sodium (2300 mg day−1). Food contribution analysis revealed that most vitamins were derived from low-quality foods (i.e. fast-food). Conclusions: A significant proportion of adults residing in Greece have low nutrient intake and poor food selections. These results provide guidance to public health policy makers for developing strategies to improve the dietary quality in Greece. © 2021 The British Dietetic Association Ltd.
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- 2021
5. The recalibrated HellenicSCORE based on newly derived risk factors from the Hellenic National Nutrition and Health Survey (HNNHS); the HellenicSCORE II
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Panagiotakos, D.B. Magriplis, E. Zampelas, A. Mitsopoulou, A.-V. Karageorgou, D. Dimakopoulos, I. Bakogianni, I. Chourdakis, M. Micha, R. Michas, G. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Chrousos, G.P. Dedoussis, G. Dimitriadis, G. Manios, Y. Roma, E. Contributors Advisory Committee
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Background: Because of the increased burden of cardiovascular disease (CVD), country specific risk prediction models to forecast future CVD events and mortality are recommended, for primary prevention. The aim of this study was to recalibrate the HellenicSCORE, to accurately estimate the 10-year risk CVD mortality of Greek adults. Methods: Data from the Hellenic National Nutrition and Health Survey (HNNHS) were used (N = 1012; 37.9% males). Information on age, smoking, systolic blood pressure (SBP), and total blood cholesterol from adults >40 years of age were derived following validated health survey protocols. Individual scores were calculated using these data and beta-coefficients derived from ESC SCORE. Results: Both updated HellenicSCORE II charts had lower risk estimates compared to the older version and were closer to the ESC SCORE charts, particularly at the extremes. No significant age difference by sex was observed (mean 59.5 (SD 13.1) years in total) in the population. Women had a significant higher mean total cholesterol compared to men [212.9 (39.5) vs 204.6 (41.2) mg/dl, respectively; p = 0.0343], but smoking prevalence and mean SBP was significantly higher in men [p for all
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- 2021
6. Prevalence of type 2 diabetes mellitus in a representative sample of Greek adults and its association with modifiable risk factors: results from the Hellenic National Nutrition and Health Survey
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Magriplis, E., primary, Panagiotakos, D., additional, Papakonstantinou, E., additional, Mitsopoulou, A.-V., additional, Karageorgou, D., additional, Dimakopoulos, I., additional, Bakogianni, I., additional, Chourdakis, M., additional, Micha, R., additional, Michas, G., additional, Ntouroupi, T., additional, Tsaniklidou, S.-M., additional, Argyri, K., additional, Dimitriadis, G., additional, Zampelas, A., additional, Fappa, E., additional, Theodoraki, E.-M., additional, Trichia, E., additional, Sialvera, T.-E., additional, Varytimiadi, A., additional, Spyreli, E., additional, Koutelidakis, A., additional, Karlis, G., additional, Zacharia, S., additional, Papageorgiou, A., additional, Chrousos, G.P., additional, Dedoussis, G., additional, Manios, Y., additional, and Roma, E., additional
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- 2021
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7. Dietary patterns and cardiovascular disease in Greek adults: The Hellenic National Nutrition and Health Survey (HNNHS)
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Karageorgou, D. Magriplis, E. Bakogianni, I. Mitsopoulou, A.V. Dimakopoulos, I. Micha, R. Michas, G. Ntouroupi, T. Tsaniklidou, S.M. Argyri, K. Chourdakis, M. Panagiotakos, D.B. Zampelas, A. Fappa, E. Theodoraki, E.M. Trichia, I. Sialvera, T.E. Aggeliki Varytimiadi, A. Spyrelli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Chrousos, G.P. Dedoussis, G. Dimitriadis, G. Manios, I. Roma, E. HNNHS Contributors
- Abstract
Background and aims: Empirically-derived dietary patterns have been shown to have both positive and adverse associations with cardiovascular disease (CVD). Yet, such associations remain unclear in the Greek population. The aim of this study was to investigate the association between empirically-derived dietary patterns and the presence of CVD and CVD-related medical conditions in a nationally representative sample of Greek adults. Methods and results: Adult participants (≥20 years old) of the Hellenic National Nutrition and Health Survey (HNNHS) were included (N = 3552; 41.2% men; 43.7 years, SD: 18.1). Dietary patterns were derived by principal component analysis using 24-h recall data. The presence of dyslipidemia (elevated cholesterol and/or triglycerides), hypertension, coronary heart disease, and total CVD, was defined according to the International Clinical Diagnosis (ICD)-10 codes. Odds ratios of CVD outcomes were estimated across dietary patterns using multivariable logistic regression analysis. Three dietary patterns -Traditional (proxy Mediterranean), Western, and Prudent-were identified explaining 16.5% of the total variance in consumption. Logistic regression analysis, adjusted for age, sex, total caloric intake, sociodemographic characteristics, and other CVD risk factors, showed an inverse association between the Traditional dietary pattern and CVD presence (OR: 0.53; 95% CI: 0.30–0.95), and a positive association between the Western pattern and dyslipidemia (1.52; 1.02–2.26). No association was found between the Prudent pattern and CVD outcomes. Conclusion: The variability of food intake combinations in the Greek population seem to be associated with the presence of CVD and CVD related conditions. Such findings are imperative for national monitoring and informed priority setting. © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University
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- 2020
8. Presence of hypertension is reduced by mediterranean diet adherence in all individuals with a more pronounced effect in the obese: The hellenic national nutrition and health survey (HNNHS)
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Magriplis, E. Panagiotakos, D. Kyrou, I. Tsioufis, C. Mitsopoulou, A.-V. Karageorgou, D. Dimakopoulos, I. Bakogianni, I. Chourdakis, M. Micha, R. Michas, G. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Zampelas, A.
- Abstract
Hypertension is a major risk of cardiovascular diseases. This study’s aim was to examine associations between hypertension and a priori known lifestyle risk factors, including weight status and Mediterranean diet adherence. The study included a representative sample of the adult population (N = 3775 (40.8% males)), from the Hellenic National Nutrition and Health Survey (HNNHS), which took place from September 2013 to May 2015. Demographic and anthropometric data were collected using validated questionnaires, and blood pressure (BP) measurements were performed for the two main metropolitan areas (N = 1040; 41.1%). Hypertension diagnosis was according to the International Classification of Diseases (ICD-10) guidelines. Weighted proportions, extended Mantel–Haenszel (M–H) analyses, and multiple logistic regressions (for the survey data) were performed. Mean systolic BP (SBP) and diastolic BP (DBP) were 118.6 mmHg and 72.2 mmHg respectively, with both values being higher in males compared to females in all age groups (p < 0.001). Study participants with hyperlipidemia or diabetes, and those overweight, were almost twice as likely to be hypertensives, with the odds increasing to 4 for those obese (p for all, < 0.05). Stricter Mediterranean diet adherence significantly decreased the likelihood of hypertension by 36% (OR: 0.64; 95% CI: 0.439, 0.943), and a significant interaction was found between Mediterranean diet adherence and weight status on hypertension. The presence of hypertension is clustered with comorbidities, but is significantly associated with modifiable risk factors, including Mediterranean diet and weight status, underlining the need for personalized medical nutritional treatment. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
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- 2020
9. Hypertension prevalence in a representative sample of Greek adults: The Hellenic National Nutrition and Health Survey (HNNHS)
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Magriplis, E. Panagiotakos, D. Tsioufis, C. Mitsopoulou, A.-V. Karageorgou, D. Dimakopoulos, I. Bakogianni, I. Chourdakis, M. Micha, R. Michas, G. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Zampelas, A. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Chrousos, G.P. Dedoussis, G. Dimitriadis, G. Manios, Y. Roma, E.
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- 2020
10. Association of serum vitamin D status with dietary intake and sun exposure in adults
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Dimakopoulos, I. Magriplis, E. Mitsopoulou, A.-V. Karageorgou, D. Bakogianni, I. Micha, R. Michas, G. Chourdakis, M. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Panagiotakos, D.B. Zampelas, A. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Chrousos, G.P. Dedoussis, G. Dimitriadis, G. Manios, Y. Roma, E. HNNHS Contributors HNNHS Advisory Committee
- Abstract
Background & aims: Serum 25(OH)D deficiency is becoming an epidemic. The aim was to assess vitamin D status of the adult Greek population in relation to intake, sun exposure and other factors, using data from the Hellenic National Nutrition and Health Survey (HNNHS). Methods: Data from 1084 adult participants (37.8% males) were analyzed. Vitamin D intake was assessed using 24-h recalls. Serum 25(OH)D concentration was evaluated and related to anthropometric measurements and other covariates including supplements used, by sex. Variables significantly associated with 25(OH)D < 20 ng/ml were assessed using simple and multiple logistic regression. Results: Median vitamin D intake from food was 1.23 mcg/day (0.60, 2.44), with 9.1% consuming supplements. Median serum 25(OH)D was 16.72 ng/ml, with no sex differences (P = 0.923). The odds of having 25(OH)D < 20 ng/ml significantly decreased with being very active (OR 0.55, 95% CI 0.35, 0.98), increasing length of sun exposure [1–3 h/day (OR 0.59, 95% CI 0.44, 0.80), >3 h/day (OR 0.36, 95% CI 0.24, 0.55)], and skin colour [light to medium skin (OR 0.47, 95% CI 0.24, 0.91), fairly dark skin colour (OR 0.34, 95% CI 0.17, 0.67) and dark or very dark skin colour (OR 0.34, 95% CI 0.15, 0.75)], compared to respective baseline levels. The odds significantly increased with obesity (OR 1.95, 95% CI 1.24, 3.08), and spring season of blood sample collection (OR 1.75, 95% CI 1.22, 2.50). Conclusions: Vitamin D deficiency is highly prevalent in Greek adults. Relevant public health policies are highly recommended, which could include vitamin D fortification. and suggestion for increased but safe sun exposure. © 2019 European Society for Clinical Nutrition and Metabolism
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- 2019
11. Association of meal and snack patterns with micronutrient intakes among Greek children and adolescents: data from the Hellenic National Nutrition and Health Survey
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Mitsopoulou, A. -V. Magriplis, E. Dimakopoulos, I. and Karageorgou, D. Bakogianni, I. Micha, R. Michas, G. and Chourdakis, M. Ntouroupi, T. Tsaniklidou, S. -M. Argyri, K. and Panagiotakos, D. B. Zampelas, A. Fappa, Evangelia and Theodoraki, Eleni-Maria Trichia, Eirini Sialvera, Theodora-Eirini Varytimiadi, Aggeliki Spyreli, Eleni and Koutelidakis, Antonis Karlis, George Zacharia, Stauroula and Papageorgiou, Anna Chrousos, George P. Dedoussis, Georgios and Dimitriadis, George Manios, Yannis Roma, Eleftheria HNNHS Contributors HNNHS Advisory Comm
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digestive, oral, and skin physiology ,food and beverages - Abstract
Background The present study aimed to examine how different meal and snack patterns are associated with micronutrient intakes and diet quality among a nationally representative sample of Greek children and adolescents aged 1-19 years from the cross-sectional Hellenic National Nutrition and Health Survey (n = 598). Methods Meal and snack patterns were derived using 24-h dietary recalls. Mean adequacy ratio (MAR) was used as an overall measure of diet quality. Multiple linear regression adjusted for covariates was conducted to examine associations between eating patterns, nutrient intakes and MAR. Results Four most frequently reported eating schemes were identified including breakfast (B), lunch (L), dinner (D) and two snacks (S) (20.9%); B, L, D and 1S (16.2%); B, L, D and 3S (10.8%); and B, L and D (7.9%). Based on these schemes, the daily consumption of all main meals from the majority of the sample was highlighted. In children and adolescents aged 4-19 years, increasing snack frequency was positively associated with intakes of vitamin D, vitamin K, riboflavin, niacin, pantothenic acid, folate, magnesium, copper and selenium. An inverse association was recorded for vitamin E, vitamin B-6, calcium and iron. Among children aged 1-3 years, only niacin and copper were significantly associated with number of snacks, with the group of ‘B-L-D-2S’ presenting the highest intake. As for the overall diet quality, among all participants, there was no significant association of MAR with the type of meal and snack pattern, and thus the snack frequency. Conclusions Snacking behaviour is a common practice among children and adolescents. Modifying current snack foods with nutrient-rich choices could lead to an improvement of their diet’s nutritional quality.
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- 2019
12. Frequency and quantity of egg intake is not associated with dyslipidemia: The hellenic national nutrition and health survey (HNNHS)
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Magriplis, E. Mitsopoulou, A.-V. Karageorgou, D. Bakogianni, I. Dimakopoulos, I. Micha, R. Michas, G. Chourdakis, M. Chrousos, G.P. Roma, E. Panagiotakos, D. Zampelas, A. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Ntouroupi, T. Tsaniklidou, S.-M. Argyri, K. Dedoussis, G. Dimitriadis, G. Manios, Y. Adami, I. Anastasiou, A. Anestiadou, E. Altanis, N. Argyropoulos, G. Arvanitidou, E. Barounis, A. Basdeki, A. Bazakidis, P. Borsa, D. Chatzistergiou, V. Chrysanidis, T. Daskalou, K. Galanaki, C. Gerasimatou, C. Gkouvi, A. Grampsas, L. Ioannidi, E. Kanaki, V. Karagiannidis, E. Kasapidou, E. Katseni, V. Koktsidis, G. Konstantakou, E. Kostakidis, A. Kottara, S. Kourliti, E. Kourtidou, M. Lymperopoulou, A. Markoglou, N. Markou, A. Mauromanoli, A. Merou, P. Miha, A. Moira, M. Moschakis, I. Mougopetrou, D. Mouliou, K. Mourtzouhou, A. Moustakaki, V. Moutsanas, V. Mpoulet, M.A. Nanou, E. Nikolaidis, I. Nikolaou, G.-A. Panagiotakis, S. Panagiotou, E. Papadopoulos, P. Papageorgiou, V. Papaspanos, N. Papazisi, O. Pappa, E.-I. Patiraki, E. Petsanis, K. Polychronopoulou, M.-C. Psylia, N. Sachinidis, A. Sarafopoulos, A. Seferidi, P. Sifnaios, C. Stauropoulou, D. Stavrou, M. Tatsi, C. Theodoridou, N. Theou, A. Tzotziou, C.-Y. Vergos, G. Vlachou, A. Xatziapostolou, A. Xatzifragou, I. Zana, A. HNNHS Advisory Committee
- Abstract
Background: Gaps remain on the safety of egg intake on cardiovascular health, setting the study’s aim to investigate the association between quantity and frequency of egg consumption, with established dyslipidemia. Methods: Study participants (N = 3558, 40.3% males) included individuals from the Hellenic National and Nutrition Health Survey (HNNHS), of national representation. Quantity and frequency of egg consumption was determined. Minimally adjusted, multivariable logistic and linear analysis were used to assess egg consumption and dyslipidemia. Results: The more frequent egg consumption compared to no or rare egg consumption significantly decreased the odds of dyslipidemia in the minimally adjusted (Odds Ratio (OR) for frequency: 0.83; 95% Confidence Interval (CI): 0.752, 0.904; OR for quantified frequency: 0.87; 95% CI: 0.796, 0.963) and the fully adjusted models (OR for frequency: 0.80; 95% CI: 0.718, 0.887; OR for quantified frequency: 0.85; 95%CI: 0.759, 0.945). Level of serum cholesterol and LDL-c were significantly lower with higher frequency and quantified frequency of egg consumption in all models. Conclusion: Eggs do not increase the risk of dyslipidemia and can be consumed as part of a healthy diet that is high in fiber and low in saturated fat, without excessive energy intake, by all individuals. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
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- 2019
13. Dietary patterns and lifestyle characteristics in adults: results from the Hellenic National Nutrition and Health Survey (HNNHS)
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Karageorgou, D. Magriplis, E. Mitsopoulou, A.V. Dimakopoulos, I. Bakogianni, I. Micha, R. Michas, G. Chourdakis, M. Ntouroupi, T. Tsaniklidou, S.M. Argyri, K. Panagiotakos, D.B. Zampelas, A. Fappa, E. Theodoraki, E.-M. Trichia, E. Sialvera, T.-E. Varytimiadi, A. Spyreli, E. Koutelidakis, A. Karlis, G. Zacharia, S. Papageorgiou, A. Chrousos, G.P. Dedoussis, G. Dimitriadis, G. Manios, I. Roma, E. HNNHS Contributors HNNHS Advisory Committee
- Abstract
Objectives: The objective of this study was to identify and describe different dietary patterns in a nationally representative sample of Greek adults and to assess potential associations with lifestyle characteristics. Study design: This was a cross-sectional study. Methods: Dietary patterns were derived by principal component analysis using individual dietary data (24-h recall) of 3552 participants of the Hellenic National Nutrition and Health Survey (HNNHS). Analysis of variance and chi-squared test were used to determine the lifestyle characteristics of the participants following each pattern. Results: Three dietary patterns were identified explaining 16.5% of variance; a traditional pattern, loading positively on olive oil, non-starchy vegetables, and cheese; a Western pattern, loading positively on refined grains, processed meats, and animal fats; and a prudent pattern, loading positively on fruits, whole grains, and yoghurt and negatively on fast food. A fourth, snack-type pattern, loading positively on sweets, salty snacks, and nuts, was identified in women. Primary crude results revealed an association between dietary patterns and socio-economic status. In multivariate analysis, highest adherence to the prudent pattern was associated with higher protein and unsaturated fat intake and lower energy and saturated fat intake (all P ≤ 0.05); the Western and traditional patterns were associated with higher energy and total and saturated fat intake. The traditional pattern was additionally associated with higher monounsaturated fatty acids intake, whereas the Western pattern, with higher alcohol intake (all P ≤ 0.001). Conclusions: These findings are valuable for understanding the dietary behaviors of adults in Greece and enabling more focused public health policies for the promotion of healthier food behaviors in the future. © 2019 The Royal Society for Public Health
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- 2019
14. Dietary patterns and lifestyle characteristics in adults: results from the Hellenic National Nutrition and Health Survey (HNNHS)
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Karageorgou, D., primary, Magriplis, E., additional, Mitsopoulou, A.V., additional, Dimakopoulos, I., additional, Bakogianni, I., additional, Micha, R., additional, Michas, G., additional, Chourdakis, M., additional, Ntouroupi, T., additional, Tsaniklidou, S.M., additional, Argyri, K., additional, Panagiotakos, D.B., additional, Zampelas, A., additional, Fappa, E., additional, Theodoraki, E.-M., additional, Trichia, E., additional, Sialvera, T.-E., additional, Varytimiadi, A., additional, Spyreli, E., additional, Koutelidakis, A., additional, Karlis, G., additional, Zacharia, S., additional, Papageorgiou, A., additional, Chrousos, G.P., additional, Dedoussis, G., additional, Dimitriadis, G., additional, Manios, I., additional, and Roma, E., additional
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- 2019
- Full Text
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15. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope (Ikoniscope (R))
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Ntouroupi, T and Bodmer, W
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- 2016
16. Association of meal and snack patterns with micronutrient intakes among Greek children and adolescents: data from the Hellenic National Nutrition and Health Survey.
- Author
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Mitsopoulou, A.‐V., Magriplis, E., Dimakopoulos, I., Karageorgou, D., Bakogianni, I., Micha, R., Michas, G., Chourdakis, M., Ntouroupi, T., Tsaniklidou, S.‐M., Argyri, K., Panagiotakos, D. B., and Zampelas, A.
- Subjects
COPPER analysis ,IRON analysis ,SELENIUM analysis ,VITAMIN E analysis ,BREAKFASTS ,CALCIUM ,FOLIC acid ,FOOD habits ,INGESTION ,LUNCHEONS ,MAGNESIUM ,NIACIN ,NUTRITIONAL assessment ,QUESTIONNAIRES ,SNACK foods ,MICRONUTRIENTS ,VITAMIN B2 ,VITAMIN B6 ,VITAMIN D ,VITAMIN K ,PANTOTHENIC acid ,MULTIPLE regression analysis ,FOOD diaries ,NUTRITIONAL value ,ADOLESCENCE ,CHILDREN - Abstract
Background: The present study aimed to examine how different meal and snack patterns are associated with micronutrient intakes and diet quality among a nationally representative sample of Greek children and adolescents aged 1–19 years from the cross‐sectional Hellenic National Nutrition and Health Survey (n = 598). Methods: Meal and snack patterns were derived using 24‐h dietary recalls. Mean adequacy ratio (MAR) was used as an overall measure of diet quality. Multiple linear regression adjusted for covariates was conducted to examine associations between eating patterns, nutrient intakes and MAR. Results: Four most frequently reported eating schemes were identified including breakfast (B), lunch (L), dinner (D) and two snacks (S) (20.9%); B, L, D and 1S (16.2%); B, L, D and 3S (10.8%); and B, L and D (7.9%). Based on these schemes, the daily consumption of all main meals from the majority of the sample was highlighted. In children and adolescents aged 4–19 years, increasing snack frequency was positively associated with intakes of vitamin D, vitamin K, riboflavin, niacin, pantothenic acid, folate, magnesium, copper and selenium. An inverse association was recorded for vitamin E, vitamin B6, calcium and iron. Among children aged 1–3 years, only niacin and copper were significantly associated with number of snacks, with the group of 'B‐L‐D‐2S' presenting the highest intake. As for the overall diet quality, among all participants, there was no significant association of MAR with the type of meal and snack pattern, and thus the snack frequency. Conclusions: Snacking behaviour is a common practice among children and adolescents. Modifying current snack foods with nutrient‐rich choices could lead to an improvement of their diet's nutritional quality. [ABSTRACT FROM AUTHOR]
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- 2019
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17. Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis
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Ashraf, S Q, primary, Umana, P, additional, Mössner, E, additional, Ntouroupi, T, additional, Brünker, P, additional, Schmidt, C, additional, Wilding, J L, additional, Mortensen, N J, additional, and Bodmer, W F, additional
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- 2009
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18. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope
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Ntouroupi, T G, primary, Ashraf, S Q, additional, McGregor, S B, additional, Turney, B W, additional, Seppo, A, additional, Kim, Y, additional, Wang, X, additional, Kilpatrick, M W, additional, Tsipouras, P, additional, Tafas, T, additional, and Bodmer, W F, additional
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- 2008
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19. Analysis of circulating tumor cells in prostate, colorectal and ovarian cancer using robotic microscopy
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Romas, N., primary, Kilpatrick, M. W., additional, Ntouroupi, T. G., additional, Seppo, A., additional, Kim, Y., additional, Cohen, S., additional, Bodmer, W. F., additional, Tsipouras, P., additional, and Tafas, T., additional
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- 2008
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20. Heart failure in Greece: The Hellenic National Nutrition and Health Survey (HNNHS).
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Michas G, Magriplis E, Panagiotakos D, Chourdakis M, Micha R, Filippatos G, Zampelas A, Dimakopoulos I, Karageorgou D, Mitsopoulou AV, Bakogianni I, Ntouroupi T, Tsaniklidou SM, Argyri K, Fappa E, Theodoraki EM, Trichia E, Sialvera TE, Varytimiadi A, Spyreli E, Koutelidakis A, Karlis G, Zacharia S, Papageorgiou A, Chrousos GP, Dedoussis G, Dimitriadis G, Manios Y, and Roma E
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- Greece epidemiology, Health Surveys, Humans, Nutrition Surveys, Heart Failure epidemiology
- Published
- 2021
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- View/download PDF
21. Micronutrient dietary intakes and their food sources in adults: the Hellenic National Nutrition and Health Survey (HNNHS).
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Mitsopoulou AV, Magriplis E, Michas G, Micha R, Chourdakis M, Chrousos GP, Roma E, Panagiotakos DB, Zampelas A, Karageorgou D, Bakogianni I, Dimakopoulos I, Ntouroupi T, Tsaniklidou SM, Argyri K, Fappa E, Theodoraki EM, Trichia E, Sialvera TE, Varytimiadi A, Spyreli E, Koutelidakis A, Karlis G, Zacharia S, Papageorgiou A, Dedoussis G, Dimitriadis G, and Manios I
- Subjects
- Adult, Aged, Diet statistics & numerical data, Female, Food statistics & numerical data, Greece epidemiology, Humans, Male, Middle Aged, Nutrition Surveys, Recommended Dietary Allowances, Diet standards, Food classification, Micronutrients administration & dosage, Nutritional Requirements, Nutritional Status
- Abstract
Background: The present study aimed to assess micronutrient intake among Greek adults and to identify the main food sources that contribute to it., Methods: Food consumption data from 2389 participants in the Hellenic National Nutrition and Health Survey (HNNHS), collected with 24-h recalls, was used to calculate micronutrient intakes. Usual nutrient intake was estimated according to the National Cancer Institute method. Nutrient adequacy was estimated using the estimated average requirement (EAR) cut-point method, when available, or adequate intake otherwise. The probability approach was used to determine iron intake adequacy in females of reproductive age. Food group contribution for each nutrient assessed was derived to identify their main food sources., Results: Almost all individuals had vitamin D intake below EAR, whereas vitamins A, E, K and C, as well as potassium intake, were also insufficient in a considerable percentage of the population (>70% in most age groups). Calcium intake was substantially below the EAR for females aged >50 years and males >70 years; the same for magnesium in males >70 years. Furthermore, 50% of females, including those of reproductive age, had intake of folate below EAR. More than 50% of the population (to 79%) exceeded the upper tolerable limit for sodium (2300 mg day
-1 ). Food contribution analysis revealed that most vitamins were derived from low-quality foods (i.e. fast-food)., Conclusions: A significant proportion of adults residing in Greece have low nutrient intake and poor food selections. These results provide guidance to public health policy makers for developing strategies to improve the dietary quality in Greece., (© 2021 The British Dietetic Association Ltd.)- Published
- 2021
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- View/download PDF
22. Micronutrient intakes and their food sources among Greek children and adolescents.
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Mitsopoulou AV, Magriplis E, Dimakopoulos I, Karageorgou D, Bakogianni I, Micha R, Michas G, Chourdakis M, Ntouroupi T, Tsaniklidou SM, Argyri K, Panagiotakos DB, and Zampelas A
- Subjects
- Adolescent, Child, Cross-Sectional Studies, Female, Greece, Humans, Male, Nutrition Surveys, Nutritional Requirements, Vitamins administration & dosage, Diet, Micronutrients administration & dosage
- Abstract
Objective: To assess the usual dietary intake of twenty micronutrients and to identify their food sources in a representative sample of Greek children and adolescents., Design: Cross-sectional data from the Hellenic National Nutrition and Health Survey (HNNHS). Vitamin and mineral intakes were estimated from two 24 h dietary recalls by sex and age groups. Estimates were calculated using the National Research Council method and the statistical software package Stata13 to account for within- and between-person variations. The prevalence of nutrients' inadequacy among sample was estimated using the estimated average requirement (EAR) cut-point method. The contribution of food groups to nutrient intake was estimated to identify micronutrients food sources., Setting: Greece., Participants: Children and adolescents aged 1-19 years (n 577) who provided sufficient and plausible 24-h recalls., Results: A substantial percentage of children and adolescents had insufficient intakes of numerous micronutrients. Usual intake of vitamins D, K and potassium was inadequate in practically all individuals. Vitamin A, folate, Ca and Mg were also insufficient to a considerable percentage, especially in girls aged 14-18 years. Pantothenic acid was highlighted as nutrient of interest since only one out of ten boys 9-13 years and girls 14-19 years had intake above the EAR. Data demonstrated that food groups highly ranked in energy contribution were not necessarily important sources of micronutrients., Conclusions: Results suggest that micronutrient density of Greek children and adolescents' diet should be improved. These findings might be used by public health policy-makers to help young people optimise their food choices in Greece.
- Published
- 2020
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23. Hypertension prevalence in a representative sample of Greek adults: The Hellenic National Nutrition and Health Survey (HNNHS).
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Magriplis E, Panagiotakos D, Tsioufis C, Mitsopoulou AV, Karageorgou D, Dimakopoulos I, Bakogianni I, Chourdakis M, Micha R, Michas G, Ntouroupi T, Tsaniklidou SM, Argyri K, Zampelas A, Koutelidakis A, Karlis G, Zacharia S, Papageorgiou A, Dedoussis G, Dimitriadis G, Manios Y, and Roma E
- Subjects
- Adult, Cross-Sectional Studies, Greece epidemiology, Health Surveys, Humans, Prevalence, Hypertension epidemiology
- Published
- 2020
- Full Text
- View/download PDF
24. Presence of Hypertension Is Reduced by Mediterranean Diet Adherence in All Individuals with a More Pronounced Effect in the Obese: The Hellenic National Nutrition and Health Survey (HNNHS).
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Magriplis E, Panagiotakos D, Kyrou I, Tsioufis C, Mitsopoulou AV, Karageorgou D, Dimakopoulos I, Bakogianni I, Chourdakis M, Micha R, Michas G, Ntouroupi T, Tsaniklidou SM, Argyri K, and Zampelas A
- Subjects
- Adult, Cardiovascular Diseases etiology, Comorbidity, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Humans, Hyperlipidemias, Hypertension diet therapy, Male, Middle Aged, Observational Studies as Topic, Risk, Surveys and Questionnaires, Young Adult, Diet, Mediterranean, Hypertension etiology, Hypertension prevention & control, Obesity complications
- Abstract
Hypertension is a major risk of cardiovascular diseases. This study's aim was to examine associations between hypertension and a priori known lifestyle risk factors, including weight status and Mediterranean diet adherence. The study included a representative sample of the adult population (N = 3775 (40.8% males)), from the Hellenic National Nutrition and Health Survey (HNNHS), which took place from September 2013 to May 2015. Demographic and anthropometric data were collected using validated questionnaires, and blood pressure (BP) measurements were performed for the two main metropolitan areas (N = 1040; 41.1%). Hypertension diagnosis was according to the International Classification of Diseases (ICD-10) guidelines. Weighted proportions, extended Mantel-Haenszel (M-H) analyses, and multiple logistic regressions (for the survey data) were performed. Mean systolic BP (SBP) and diastolic BP (DBP) were 118.6 mmHg and 72.2 mmHg respectively, with both values being higher in males compared to females in all age groups ( p < 0.001). Study participants with hyperlipidemia or diabetes, and those overweight, were almost twice as likely to be hypertensives, with the odds increasing to 4 for those obese ( p for all, < 0.05). Stricter Mediterranean diet adherence significantly decreased the likelihood of hypertension by 36% (OR: 0.64; 95% CI: 0.439, 0.943), and a significant interaction was found between Mediterranean diet adherence and weight status on hypertension. The presence of hypertension is clustered with comorbidities, but is significantly associated with modifiable risk factors, including Mediterranean diet and weight status, underlining the need for personalized medical nutritional treatment.
- Published
- 2020
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25. Dietary patterns and cardiovascular disease in Greek adults: The Hellenic National Nutrition and Health Survey (HNNHS).
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Karageorgou D, Magriplis E, Bakogianni I, Mitsopoulou AV, Dimakopoulos I, Micha R, Michas G, Ntouroupi T, Tsaniklidou SM, Argyri K, Chourdakis M, Panagiotakos DB, and Zampelas A
- Subjects
- Adult, Cardiovascular Diseases diagnosis, Cardiovascular Diseases epidemiology, Cross-Sectional Studies, Dyslipidemias epidemiology, Dyslipidemias prevention & control, Energy Intake, Female, Greece epidemiology, Humans, Hypertension epidemiology, Hypertension prevention & control, Male, Middle Aged, Nutrition Surveys, Nutritive Value, Prevalence, Protective Factors, Recommended Dietary Allowances, Risk Assessment, Risk Factors, Young Adult, Cardiovascular Diseases prevention & control, Diet, Healthy, Diet, Mediterranean, Diet, Western adverse effects, Feeding Behavior, Risk Reduction Behavior
- Abstract
Background and Aims: Empirically-derived dietary patterns have been shown to have both positive and adverse associations with cardiovascular disease (CVD). Yet, such associations remain unclear in the Greek population. The aim of this study was to investigate the association between empirically-derived dietary patterns and the presence of CVD and CVD-related medical conditions in a nationally representative sample of Greek adults., Methods and Results: Adult participants (≥20 years old) of the Hellenic National Nutrition and Health Survey (HNNHS) were included (N = 3552; 41.2% men; 43.7 years, SD: 18.1). Dietary patterns were derived by principal component analysis using 24-h recall data. The presence of dyslipidemia (elevated cholesterol and/or triglycerides), hypertension, coronary heart disease, and total CVD, was defined according to the International Clinical Diagnosis (ICD)-10 codes. Odds ratios of CVD outcomes were estimated across dietary patterns using multivariable logistic regression analysis. Three dietary patterns -Traditional (proxy Mediterranean), Western, and Prudent-were identified explaining 16.5% of the total variance in consumption. Logistic regression analysis, adjusted for age, sex, total caloric intake, sociodemographic characteristics, and other CVD risk factors, showed an inverse association between the Traditional dietary pattern and CVD presence (OR: 0.53; 95% CI: 0.30-0.95), and a positive association between the Western pattern and dyslipidemia (1.52; 1.02-2.26). No association was found between the Prudent pattern and CVD outcomes., Conclusion: The variability of food intake combinations in the Greek population seem to be associated with the presence of CVD and CVD related conditions. Such findings are imperative for national monitoring and informed priority setting., Competing Interests: Declaration of Competing Interest RM reports grants from NIH/NHLBI, grants from Unilever R&D, grants from Bill and Melinda Gates Foundation, personal fees from World Bank and personal fees from Bunge., (Copyright © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. All rights reserved.)
- Published
- 2020
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- View/download PDF
26. Association of serum vitamin D status with dietary intake and sun exposure in adults.
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Dimakopoulos I, Magriplis E, Mitsopoulou AV, Karageorgou D, Bakogianni I, Micha R, Michas G, Chourdakis M, Ntouroupi T, Tsaniklidou SM, Argyri K, Panagiotakos DB, and Zampelas A
- Subjects
- Adult, Cross-Sectional Studies, Dietary Supplements, Female, Greece, Humans, Male, Middle Aged, Nutritional Status, Obesity complications, Public Health, Seasons, Vitamin D Deficiency blood, Vitamin D Deficiency prevention & control, Nutrition Surveys, Sunlight, Vitamin D blood
- Abstract
Background & Aims: Serum 25(OH)D deficiency is becoming an epidemic. The aim was to assess vitamin D status of the adult Greek population in relation to intake, sun exposure and other factors, using data from the Hellenic National Nutrition and Health Survey (HNNHS)., Methods: Data from 1084 adult participants (37.8% males) were analyzed. Vitamin D intake was assessed using 24-h recalls. Serum 25(OH)D concentration was evaluated and related to anthropometric measurements and other covariates including supplements used, by sex. Variables significantly associated with 25(OH)D < 20 ng/ml were assessed using simple and multiple logistic regression., Results: Median vitamin D intake from food was 1.23 mcg/day (0.60, 2.44), with 9.1% consuming supplements. Median serum 25(OH)D was 16.72 ng/ml, with no sex differences (P = 0.923). The odds of having 25(OH)D < 20 ng/ml significantly decreased with being very active (OR 0.55, 95% CI 0.35, 0.98), increasing length of sun exposure [1-3 h/day (OR 0.59, 95% CI 0.44, 0.80), >3 h/day (OR 0.36, 95% CI 0.24, 0.55)], and skin colour [light to medium skin (OR 0.47, 95% CI 0.24, 0.91), fairly dark skin colour (OR 0.34, 95% CI 0.17, 0.67) and dark or very dark skin colour (OR 0.34, 95% CI 0.15, 0.75)], compared to respective baseline levels. The odds significantly increased with obesity (OR 1.95, 95% CI 1.24, 3.08), and spring season of blood sample collection (OR 1.75, 95% CI 1.22, 2.50)., Conclusions: Vitamin D deficiency is highly prevalent in Greek adults. Relevant public health policies are highly recommended, which could include vitamin D fortification. and suggestion for increased but safe sun exposure., (Copyright © 2019 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2019
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27. Aims, design and preliminary findings of the Hellenic National Nutrition and Health Survey (HNNHS).
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Magriplis E, Dimakopoulos I, Karageorgou D, Mitsopoulou AV, Bakogianni I, Micha R, Michas G, Ntouroupi T, Tsaniklidou SM, Argyri K, Danezis G, Georgiou C, Panagiotakos DB, and Zampelas A
- Subjects
- Adolescent, Adult, Aged, Cardiovascular Diseases epidemiology, Diabetes Mellitus epidemiology, Female, Greece epidemiology, Health Surveys statistics & numerical data, Humans, Hypertension epidemiology, Male, Middle Aged, Nutrition Surveys statistics & numerical data, Obesity epidemiology, Prevalence, Risk Factors, Young Adult, Health Status, Health Surveys methods, Nutrition Surveys methods, Nutritional Status
- Abstract
Background: The aim of the Hellenic National Nutrition and Health Survey was to assess nutritional intake, health status and various behaviors in a representative sample of the Greek population., Methods: Data collection took place from 01.09.2013 to 31.05.2015. Random stratified sampling was performed by (a) geographical density criteria of Greece (7 regions), (b) age group of the reference population (< 19, 20-64 and > 65 years) and (c) gender distribution. The final population enrolled included (throughout Greece), 4574 individuals (42.5% men; 57.5% women of who 47.2% were from Athens metropolitan area, 18.5% from Central Macedonia, and the remaining 34% almost equally scattered throughout the country (p for the comparisons with official statistics by region, age group and sex > 0.7). Questionnaires developed were based on extensive review of the literature, following a validation procedure when necessary., Results: Preliminary analyses revealed that 32% of the adult population were overweight and 15.5% were obese, with significant gender differences in total and per age group (p < 0.001, for all). The majority of the adult population reported being active smokers (50.4%) or regular alcohol consumers (72.4%); with significant gender differences (p < 0.001, for all). Prevalence of hyperlipidemia was 16.7%, cardiovascular disease 13.9%, hypertension 13.3%, thyroid disease 13.8%, and Diabetes Mellitus 3.6%. Significant gender and age group differences were found in various diseases., Conclusions: Study's preliminary results provide valuable information about the Hellenic population's health. Findings from this survey could be used to detect disease risk factors for public health prevention policies and programs.
- Published
- 2019
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28. Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells.
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Trougakos IP, Pawelec G, Tzavelas C, Ntouroupi T, and Gonos ES
- Subjects
- Cell Proliferation, Clusterin genetics, Dose-Response Relationship, Drug, Erythrocytes metabolism, HL-60 Cells, Hematopoietic Stem Cells drug effects, Hematopoietic Stem Cells immunology, Humans, K562 Cells, Lipopolysaccharide Receptors metabolism, Micronutrients pharmacology, Monocytes metabolism, T-Lymphocytes drug effects, Time Factors, Transfection, Up-Regulation, Zinc pharmacology, Cell Differentiation drug effects, Cellular Senescence drug effects, Clusterin metabolism, Hematopoietic Stem Cells metabolism, Micronutrients metabolism, T-Lymphocytes metabolism, Zinc metabolism
- Abstract
Clusterin/Apolipoprotein J (CLU) is a cellular senescence biomarker implicated in several physiological processes. In this work we have investigated CLU expression and function in human haematopoietic cells. We found that early passage human T cell clones (TCC) express minimal endogenous amounts of CLU, which are significantly elevated in late passage cells. Moreover, exposure of TCC to increased levels of the essential micronutrient zinc in culture resulted in intense induction of CLU. Because haematopoietic cells cease proliferation following induction of terminal differentiation, we also studied the expression profile of CLU in the leukemic progenitor cell lines K562 and HL-60. We found that, like TCC, both cell lines express minimal endogenous levels of CLU in their actively proliferating state. However, when induced to differentiate into their distinct cell types, CLU was found to be up-regulated specifically in those cells expressing the main differentiation markers. Enforced stable over-expression of CLU in K562 cells inhibited the expression of the CD14 differentiation marker and blocked differentiation to either monocytes/megacaryoblasts or to erythrocytes. Overall, our results suggest that CLU is actively involved in both replicative senescence and terminal differentiation in different types of human haematopoietic cells.
- Published
- 2006
- Full Text
- View/download PDF
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