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11 results on '"Nuccorini, Roberta"'

1. Predicting failure of hematopoietic stem cell mobilization before it starts: the predicted poor mobilizer (pPM) score

Author

Olivieri, Jacopo, Attolico, Immacolata, Nuccorini, Roberta, Pascale, Sara Pasquina, Chiarucci, Martina, Poiani, Monica, Corradini, Paolo, Farina, Lucia, Gaidano, Gianluca, Nassi, Luca, Sica, Simona, Piccirillo, Nicola, Pioltelli, Pietro Enrico, Martino, Massimo, Moscato, Tiziana, Pini, Massimo, Zallio, Francesco, Ciceri, Fabio, Marktel, Sarah, Mengarelli, Andrea, Musto, Pellegrino, Capria, Saveria, Merli, Francesco, Codeluppi, Katia, Mele, Giuseppe, Lanza, Francesco, Specchia, Giorgina, Pastore, Domenico, Milone, Giuseppe, Saraceni, Francesco, Di Nardo, Elvira, Perseghin, Paolo, and Olivieri, Attilio

Published
2018
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2. Evaluation of serological response to anti-SARS-CoV-2 mRNA vaccination in hematological patients

Author

Pascale, Sara Pasquina, primary, Nuccorini, Roberta, additional, Pierri, Teresa, additional, Di Mare, Roberta, additional, Fabio, Lucia, additional, Lerose, Emilia, additional, Merlino, Maria Antonietta, additional, Schiavo, Pietro, additional, Amendola, Angela, additional, Brucoli, Gino, additional, Caputo, Maria Denise, additional, Chitarrelli, Ida, additional, Cimminiello, Michele, additional, Coluzzi, Sabrina, additional, Filardi, Nunzio Biagio, additional, Matturro, Angela, additional, Vertone, Domenico, additional, Poggiaspalla, Monica, additional, Malaspina, Francesco, additional, Musuraca, Gerardo, additional, Coralluzzo, Gennaro, additional, Mannarella, Clara, additional, Musto, Clelia, additional, Bellettieri, Angela Pia, additional, Martinelli, Giovanni, additional, Cerchione, Claudio, additional, and Pizzuti, Michele, additional

Published
2022
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3. Long-term outcome and prospective validation of NIH response criteria in 39 patients receiving imatinib for steroid-refractory chronic GVHD

Author

Olivieri, Attilio, Cimminiello, Michele, Corradini, Paolo, Mordini, Nicola, Fedele, Roberta, Selleri, Carmine, Onida, Francesco, Patriarca, Francesca, Pavone, Enzo, Svegliati, Silvia, Gabrielli, Armando, Bresciani, Paola, Nuccorini, Roberta, Pascale, Sara, Coluzzi, Sabrina, Pane, Fabrizio, Poloni, Antonella, Olivieri, Jacopo, Leoni, Pietro, and Bacigalupo, Andrea

Published
2013
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6. Nilotinib For Steroid-Refractory Chronic Graft Versus Host Disease (SR-cGVHD): Preliminary Results Of a Phase I-II GITMO Study (Gruppo Italiano Trapianto di Midollo Osseo)

Author

Olivieri, Attilio, primary, Cimminiello, Michele, additional, Latesoriere, Ivana, additional, Leoni, Pietro, additional, Onida, Francesco, additional, Fedele, Roberta, additional, Corradini, Paolo, additional, Pavone, Vincenzo, additional, Nuccorini, Roberta, additional, Pascale, Sara Pasquina, additional, Olivieri, Jacopo, additional, Mancini, Giorgia, additional, Mammoliti, Sonia, additional, and Rambaldi, Alessandro, additional

Published
2013
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7. Association Between Immunoparesis and a Skewed Free Light Chain (FLC) Ratio: A New Prognostic Factor Of Progression from MGUS To Multiple Myeloma?

Author

Pizzuti, Michele, primary, Santagostino, Alberto, additional, Smaldore, Giuseppina, additional, Chitarrelli, Ida, additional, Vertone, Domenico, additional, Pascale, Sara Pasquina, additional, Matturro, Angela, additional, Attolico, Immacolata, additional, Amendola, Angela, additional, Cimminiello, Michele, additional, Filardi, Nunzio, additional, Girardi, Antonella, additional, Penitente, Romina, additional, Nuccorini, Roberta, additional, Coluzzi, Sabrina, additional, and Scavone, Enza, additional

Published
2013
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8. Evaluation Of Factor V Leiden, Prothrombin Mutations and The Homozygous mutation 677T In The MTHFR Gene In Patients With Venous Thrombosis

Author

Pizzuti, Michele, primary, Santagostino, Alberto, additional, Rizzo, Maria Antonietta, additional, Dragonetti, Daniela, additional, Pietrafesa, Maria Grazia, additional, Attolico, Immacolata, additional, Amendola, Angela, additional, Filardi, Nunzio, additional, Cimminiello, Michele, additional, Matturro, Angela, additional, Vertone, Domenico, additional, Nuccorini, Roberta, additional, Pascale, sara Pasquina, additional, and Coluzzi, Sabrina, additional

Published
2013
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9. Evaluation of MRD Status by Flow Cytometry and PCR in Multiple Myeloma Elderly Patients Receiving Autologous Stem Cell Transplantation After Bortezomib-Supplemented Mobilization and Conditioning

Author

Attolico, Immacolata, primary, Nuccorini, Roberta, additional, Fragasso, Alberto, additional, Pavone, Vincenzo, additional, Musto, Pellegrino, additional, Capalbo, Silvana, additional, Palumbo, Gaetano, additional, Specchia, Giorgina, additional, Carniti, Cristiana, additional, Corradini, Paolo, additional, Pascale, Sara, additional, Coluzzi, Sabrina, additional, Pizzuti, Michele, additional, Amendola, Angela, additional, Cimminiello, Michele, additional, Matturro, Angela, additional, Vertone, Domenico, additional, Filardi, Nunzio, additional, and Olivieri, Attilio, additional

Published
2012
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11. Predicting failure of hematopoietic stem cell mobilization before it starts: the Predicted Poor Mobilizer (pPM) score

Author

Nicola Piccirillo, Paolo Corradini, Domenico Pastore, Roberta Nuccorini, Giorgina Specchia, Francesco Saraceni, Massimo Martino, Massimo Pini, Sarah Marktel, Andrea Mengarelli, Pietro Pioltelli, Giuseppe Milone, Francesco Zallio, Monica Poiani, Elvira Di Nardo, Saveria Capria, Sara Pasquina Pascale, Tiziana Moscato, Gianluca Gaidano, Immacolata Attolico, Pellegrino Musto, Paolo Perseghin, Francesco Merli, Lucia Farina, Luca Nassi, Martina Chiarucci, Simona Sica, Giuseppe Mele, Jacopo Olivieri, Francesco Lanza, Attilio Olivieri, Fabio Ciceri, Katia Codeluppi, Olivieri, Jacopo, Attolico, Immacolata, Nuccorini, Roberta, Pascale, Sara Pasquina, Chiarucci, Martina, Poiani, Monica, Corradini, Paolo, Farina, Lucia, Gaidano, Gianluca, Nassi, Luca, Sica, Simona, Piccirillo, Nicola, Pioltelli, Pietro Enrico, Martino, Massimo, Moscato, Tiziana, Pini, Massimo, Zallio, Francesco, Ciceri, Fabio, Marktel, Sarah, Mengarelli, Andrea, Musto, Pellegrino, Capria, Saveria, Merli, Francesco, Codeluppi, Katia, Mele, Giuseppe, Lanza, Francesco, Specchia, Giorgina, Pastore, Domenico, Milone, Giuseppe, Saraceni, Francesco, Di Nardo, Elvira, Perseghin, Paolo, and Olivieri, Attilio

Subjects
Oncology, Adult, Male, medicine.medical_specialty, Multivariate analysis, Adolescent, lymphoma, Filgrastim, Likelihood ratios in diagnostic testing, NO, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Internal medicine, medicine, Humans, Child, Hematopoietic Stem Cell Mobilization, Aged, Retrospective Studies, Transplantation, Mobilization, Receiver operating characteristic, business.industry, Plerixafor, Patient Selection, Area under the curve, poor mobiliser, Hematology, Middle Aged, stem cell mobilization, lymphoma, myeloma, poor mobiliser, oredicting clinical score, stem cell mobilization, Settore MED/15 - MALATTIE DEL SANGUE, myeloma, oredicting clinical score, 030220 oncology & carcinogenesis, Area Under Curve, Child, Preschool, Female, business, Multiple Myeloma, 030215 immunology, medicine.drug
Abstract

Predicting mobilization failure before it starts may enable patient-tailored strategies. Although consensus criteria for predicted PM (pPM) are available, their predictive performance has never been measured on real data. We retrospectively collected and analyzed 1318 mobilization procedures performed for MM and lymphoma patients in the plerixafor era. In our sample, 180/1318 (13.7%) were PM. The score resulting from published pPM criteria had sufficient performance for predicting PM, as measured by AUC (0.67, 95%CI: 0.63–0.72). We developed a new prediction model from multivariate analysis whose score (pPM-score) resulted in better AUC (0.80, 95%CI: 0.76–0.84, p < 0001). pPM-score included as risk factors: increasing age, diagnosis of NHL, positive bone marrow biopsy or cytopenias before mobilization, previous mobilization failure, priming strategy with G-CSF alone, or without upfront plerixafor. A simplified version of pPM-score was categorized using a cut-off to maximize positive likelihood ratio (15.7, 95%CI: 9.9–24.8); specificity was 98% (95%CI: 97–98.7%), sensitivity 31.7% (95%CI: 24.9–39%); positive predictive value in our sample was 71.3% (95%CI: 60–80.8%). Simplified pPM-score can “rule in” patients at very high risk for PM before starting mobilization, allowing changes in clinical management, such as choice of alternative priming strategies, to avoid highly likely mobilization failure.

Published
2018

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