Search

Your search keyword '"Nurfadilah, Mifa"' showing total 5 results
Start Over Author "Nurfadilah, Mifa"
5 results on '"Nurfadilah, Mifa"'

1. Epigenetic studies in children at risk of stunting and their parents in India, Indonesia and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper

Author

Ramsteijn, Anouschka S, primary, Ndiaye, Magatte, additional, Kalashikam, Rajender Rao, additional, Htet, Min Kyaw, additional, Yadav DM, Dinesh, additional, Augustine, Little Flower, additional, Zahra, Nur L, additional, Djigal, Aicha, additional, Yanti, Dwi, additional, Angelin, Tiffany C, additional, Nurfadilah, Mifa, additional, Gorre, Manjula, additional, Subrahamanyam, Dantham, additional, Vadakattu, Sai Santhosh, additional, Munikumar, Manne, additional, Horgan, Graham W, additional, Fahmida, Umi, additional, Faye, Babacar, additional, Kulkarni, Bharati, additional, and Haggarty, Paul, additional

Published
2024
Full Text
View/download PDF

2. Assessment of the role of gut health in childhood stunting in a multisite, longitudinal study in India, Indonesia and Senegal: a UKRI GCRF Action Against Stunting Hub protocol

Author

Momo Kadia, Benjamin, primary, Ramsteijn, Anouschka S, additional, Dasi, Teena, additional, Fahmida, Umi, additional, Kulkarni, Bharati, additional, Faye, Babacar, additional, Htet, Min Kyaw, additional, Sow, Doudou, additional, Kalashikam, Rajender Rao, additional, Sharma, Ritu, additional, Sudibya, Arienta R P, additional, Kusuma, Sari, additional, Angelin, Tiffany C, additional, Nurfadilah, Mifa, additional, Jobarteh, Modou Lamin, additional, Diop, Ndeye Sokhna, additional, Gabain, Isobel, additional, Calvo-Urbano, Beatriz, additional, Ferguson, Elaine, additional, Haggarty, Paul, additional, Heffernan, Claire, additional, Webster, Joanne P, additional, Walker, Alan W, additional, and Allen, Stephen, additional

Published
2024
Full Text
View/download PDF

5. Evaluation of Tuberculosis Vaccine Candidate, pcDNA3.1-rpfD using Mycobacterial Growth Inhibition Assay (MGIA).

Author

Nurfadilah, Mifa, Rukmana, Andriansjah, and Sjatha, Fithriyah

Subjects
*TUBERCULOSIS vaccines, *TUBERCULOSIS, *MONONUCLEAR leukocytes, *INTERFERON gamma, *VACCINE effectiveness
Abstract

Resuscitation-promoting factor D (RpfD) is a protein involved in the resuscitation of dormant bacteria. A new tuberculosis vaccine carrying the rpfD gene has been successfully constructed, pcDNA3.1-rpfD. It was demonstrated that this vaccine exhibits cellular and humoral immune responses. Therefore, within this study, the efficacy of this new vaccine candidate was evaluated using mycobacterial growth inhibition assay (MGIA). MGIA is a functional assay that measures the complex host immune response, peripheral blood mononuclear cell (PBMC) and splenocyte from BALB/c mice against mycobacteria. With BACTECTM MGITTM 960 automated system, the effect of vaccination on bacterial growth was reported as a time to positivity (TTP) in hours. The mean of TTP from the vaccinated group (both pcDNA3.1-rpfD and BCG) was higher than the negative control group. These results suggest that pcDNA3.1-rpfD may be effective in controlling tuberculosis growth and may provide a clue for the development of the tuberculosis vaccine. In addition, despite previous evidence that IFNγ was essential for tuberculosis immunity, IFNγ (interferon gamma) production was found not to be correlated with mycobacterial inhibition. Therefore, these findings offer an alternative method to evaluate vaccine candidates than the assessment using IFNγ only. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results