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5,070 results on '"O'Connor, J"'

2. Back Cover

Author

O'Connor, J. Patrick

Published
2018

4. Bibliography

Author

O'Connor, J. Patrick

Published
2018

7. Timeline

Author

O'Connor, J. Patrick

Published
2018

8. Index

Author

O'Connor, J. Patrick

Published
2018

9. Notes

Author

O'Connor, J. Patrick

Published
2018

18. 12. Appeals

Author

O'Connor, J. Patrick

Published
2018

27. Prologue

Author

O'Connor, J. Patrick

Published
2018

31. Contents

Author

O'Connor, J. Patrick

Published
2018

37. A New Method for the High-Precision Assessment of Tumor Changes in Response to Treatment

Author

Tar, P. D., Thacker, N. A., and O'Connor, J. P. B.

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Imaging demonstrates that preclinical and human tumors are heterogeneous, i.e. a single tumor can exhibit multiple regions that behave differently during both normal development and also in response to treatment. The large variations observed in control group tumors can obscure detection of significant therapeutic effects due to the ambiguity in attributing causes of change. This can hinder development of effective therapies due to limitations in experimental design, rather than due to therapeutic failure. An improved method to model biological variation and heterogeneity in imaging signals is described. Specifically, Linear Poisson modelling (LPM) evaluates changes in apparent diffusion co-efficient (ADC) before and 72 hours after radiotherapy, in two xenograft models of colorectal cancer. The statistical significance of measured changes are compared to those attainable using a conventional t-test analysis on basic ADC distribution parameters. When LPMs were applied to treated tumors, the LPMs detected highly significant changes. The analyses were significant for all tumors, equating to a gain in power of 4 fold (i.e. equivelent to having a sample size 16 times larger), compared with the conventional approach. In contrast, highly significant changes are only detected at a cohort level using t-tests, restricting their potential use within personalised medicine and increasing the number of animals required during testing. Furthermore, LPM enabled the relative volumes of responding and non-responding tissue to be estimated for each xenograft model. Leave-one-out analysis of the treated xenografts provided quality control and identified potential outliers, raising confidence in LPM data at clinically relevant sample sizes.

Published
2022

39. Precision constraints for three-flavor neutrino oscillations from the full MINOS+ and MINOS data set

Author

Collaboration, MINOS, Adamson, P., Anghel, I., Aurisano, A., Barr, G., Blake, A., Cao, S. V., Carroll, T. J., Castromonte, C. M., Chen, R., Childress, S., Coelho, J. A. B., De Rijck, S., Evans, J. J., Feldman, G. J., Flanagan, W., Gabrielyan, M., Germani, S., Gomes, R. A., Gouffon, P., Graf, N., Grzelak, K., Habig, A., Hahn, S. R., Hartnell, J., Hatcher, R., Holin, A., Huang, J., Koerner, L. W., Kordosky, M., Kreymer, A., Lang, K., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., Mehdiyev, R., Meier, J. R., Miller, W. H., Mills, G., Naples, D., Nelson, J. K., Nichol, R. J., O'Connor, J., Pahlka, R. B., Pavlovic, Z., Pawloski, G., Perch, A., Pfutzner, M. M., Phan, D. D., Plunkett, R. K., Poonthottathil, N., Qiu, X., Radovic, A., Sail, P., Sanchez, M. C., Schneps, J., Schreckenberger, A., Sharma, R., Sousa, A., Tagg, N., Thomas, J., Thomson, M. A., Timmons, A., Todd, J., Tognini, S. C., Toner, R., Torretta, D., Vahle, P., Weber, A., Whitehead, L. H., and Wojcicki, S. G.

Subjects
High Energy Physics - Experiment
Abstract

We report the final measurement of the neutrino oscillation parameters $\Delta m^2_{32}$ and $\sin^2\theta_{23}$ using all data from the MINOS and MINOS+ experiments. These data were collected using a total exposure of $23.76 \times 10^{20}$ protons on target producing $\nu_{mu}$ and $\overline{\nu_\mu}$ beams and 60.75 kt$\cdot$yr exposure to atmospheric neutrinos. The measurement of the disappearance of $\nu_{\mu}$ and the appearance of $\nu_e$ events between the Near and Far detectors yields $|\Delta m^2_{32}|=2.40^{+0.08}_{-0.09}~(2.45^{+0.07}_{-0.08}) \times 10^{-3}$ eV$^2$ and $\sin^2\theta_{23} = 0.43^{+0.20}_{-0.04} ~(0.42^{+0.07}_{-0.03})$ at 68% C.L. for Normal (Inverted) Hierarchy., Comment: 6 pages, 4 figures, 3 tables

Published
2020
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40. Improved Constraints on Sterile Neutrino Mixing from Disappearance Searches in the MINOS, MINOS+, Daya Bay, and Bugey-3 Experiments

Author

Bay, Daya, Collaborations, MINOS, Adamson, P., An, F. P., Anghel, I., Aurisano, A., Balantekin, A. B., Band, H. R., Barr, G., Bishai, M., Blake, A., Blyth, S., Cao, G. F., Cao, J., Cao, S. V., Carroll, T. J., Castromonte, C. M., Chang, J. F., Chang, Y., Chen, H. S., Chen, R., Chen, S. M., Chen, Y., Chen, Y. X., Cheng, J., Cheng, Z. K., Cherwinka, J. J., Childress, S., Chu, M. C., Chukanov, A., Coelho, J. A. B., Cummings, J. P., Dash, N., De Rijck, S., Deng, F. S., Ding, Y. Y., Diwan, M. V., Dohnal, T., Dolzhikov, D., Dove, J., Dvořák, M., Dwyer, D. A., Evans, J. J., Feldman, G. J., Flanagan, W., Gabrielyan, M., Gallo, J. P., Germani, S., Gomes, R. A., Gonchar, M., Gong, G. H., Gong, H., Gouffon, P., Graf, N., Grzelak, K., Gu, W. Q., Guo, J. Y., Guo, L., Guo, X. H., Guo, Y. H., Guo, Z., Habig, A., Hackenburg, R. W., Hahn, S. R., Hans, S., Hartnell, J., Hatcher, R., He, M., Heeger, K. M., Heng, Y. K., Higuera, A., Holin, A., Hor, Y. K., Hsiung, Y. B., Hu, B. Z., Hu, J. R., Hu, T., Hu, Z. J., Huang, H. X., Huang, J., Huang, X. T., Huang, Y. B., Huber, P., Jaffe, D. E., Jen, K. L., Ji, X. L., Ji, X. P., Johnson, R. A., Jones, D., Kang, L., Kettell, S. H., Koerner, L. W., Kohn, S., Kordosky, M., Kramer, M., Kreymer, A., Lang, K., Langford, T. J., Lee, J., Lee, J. H. C., Lei, R. T., Leitner, R., Leung, J. K. C., Li, F., Li, H. L., Li, J. J., Li, Q. J., Li, S., Li, S. C., Li, S. J., Li, W. D., Li, X. N., Li, X. Q., Li, Y. F., Li, Z. B., Liang, H., Lin, C. J., Lin, G. L., Lin, S., Ling, J. J., Link, J. M., Littenberg, L., Littlejohn, B. R., Liu, J. C., Liu, J. L., Liu, Y., Liu, Y. H., Lu, C., Lu, H. Q., Lu, J. S., Lucas, P., Luk, K. B., Ma, X. B., Ma, X. Y., Ma, Y. Q., Mann, W. A., Marshak, M. L., Marshall, C., Caicedo, D. A. Martinez, Mayer, N., McDonald, K. T., McKeown, R. D., Mehdiyev, R., Meier, J. R., Meng, Y., Miller, W. H., Mills, G., Lepin, L. Mora, Naples, D., Napolitano, J., Naumov, D., Naumova, E., Nelson, J. K., Nichol, R. J., O'Connor, J., Ochoa-Ricoux, J. P., Olshevskiy, A., Pahlka, R. B., Pan, H. -R., Park, J., Patton, S., Pavlović, Z., Pawloski, G., Peng, J. C., Perch, A., Pfützner, M. M., Phan, D. D., Plunkett, R. K., Poonthottathil, N., Pun, C. S. J., Qi, F. Z., Qi, M., Qian, X., Qiu, X., Radovic, A., Raper, N., Ren, J., Reveco, C. Morales, Rosero, R., Roskovec, B., Ruan, X. C., Sail, P., Sanchez, M. C., Schneps, J., Schreckenberger, A., Shaheed, N., Sharma, R., Sousa, A., Steiner, H., Sun, J. L., Tagg, N., Thomas, J., Thomson, M. A., Timmons, A., Tmej, T., Todd, J., Tognini, S. C., Toner, R., Torretta, D., Treskov, K., Tse, W. -H., Tull, C. E., Vahle, P., Viren, B., Vorobel, V., Wang, C. H., Wang, J., Wang, M., Wang, N. Y., Wang, R. G., Wang, W., Wang, X., Wang, Y., Wang, Y. F., Wang, Z., Wang, Z. M., Weber, A., Wei, H. Y., Wei, L. H., Wen, L. J., Whisnant, K., White, C., Whitehead, L. H., Wojcicki, S. G., Wong, H. L. H., Wong, S. C. F., Worcester, E., Wu, D. R., Wu, F. L., Wu, Q., Wu, W. J., Xia, D. M., Xie, Z. Q., Xing, Z. Z., Xu, J. L., Xu, T., Xue, T., Yang, C. G., Yang, L., Yang, Y. Z., Yao, H. F., Ye, M., Yeh, M., Young, B. L., Yu, H. Z., Yu, Z. Y., Yue, B. B., Zeng, S., Zeng, Y., Zhan, L., Zhang, C., Zhang, F. Y., Zhang, H. H., Zhang, J. W., Zhang, Q. M., Zhang, X. T., Zhang, Y. M., Zhang, Y. X., Zhang, Y. Y., Zhang, Z. J., Zhang, Z. P., Zhang, Z. Y., Zhao, J., Zhou, L., and Zhuang, H. L.

Subjects
High Energy Physics - Experiment
Abstract

Searches for electron antineutrino, muon neutrino, and muon antineutrino disappearance driven by sterile neutrino mixing have been carried out by the Daya Bay and MINOS+ collaborations. This Letter presents the combined results of these searches, along with exclusion results from the Bugey-3 reactor experiment, framed in a minimally extended four-neutrino scenario. Significantly improved constraints on the $\theta_{\mu e}$ mixing angle are derived that constitute the most stringent limits to date over five orders of magnitude in the sterile mass-squared splitting $\Delta m^2_{41}$, excluding the 90% C.L. sterile-neutrino parameter space allowed by the LSND and MiniBooNE observations at 90% CL$_s$ for $\Delta m^2_{41}<5\,$eV$^2$.Furthermore, the LSND and MiniBooNE 99% C.L. allowed regions are excluded at 99% CL$_s$ for $\Delta m^2_{41}$ $<$ 1.2 eV$^2$., Comment: 8 pages, 4 figures

Published
2020
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42. The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 24th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2022

Author

Ducreux, M., Abou-Alfa, G.K., Bekaii-Saab, T., Berlin, J., Cervantes, A., de Baere, T., Eng, C., Galle, P., Gill, S., Gruenberger, T., Haustermans, K., Lamarca, A., Laurent-Puig, P., Llovet, J.M., Lordick, F., Macarulla, T., Mukherji, D., Muro, K., Obermannova, R., O’Connor, J.-M., O’Reilly, E.M., Osterlund, P., Philip, P., Prager, G., Ruiz-Garcia, E., Sangro, B., Seufferlein, T., Tabernero, J., Verslype, C., Wasan, H., and Van Cutsem, E.

Published
2023
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43. Design and Performance of Combined Basic Devices to Control Undesirable Bridge Deck Displacements and Damage, During Major Earthquakes

Author

Romo, M., Morales, E., Hidalgo, G., Almeida, J., Puebla, R., O’Connor, J., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Botto-Tobar, Miguel, editor, Cruz, Henry, editor, and Diaz Cadena, Angela, editor

Published
2022
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45. Quantifying Bone and Skin Movement in the Residual Limb-Socket Interface of Individuals With Transtibial Limb Loss Using Dynamic Stereo X-Ray: Protocol for a Lower Limb Loss Cadaver and Clinical Study

Author

Maikos, Jason T, primary, Chomack, John M, additional, Herlihy, David V, additional, Paglia, David N, additional, Wetterstrand, Charlene, additional, O'Connor, J Patrick, additional, Hyre, Michael J, additional, Loan, J Peter, additional, and D'Andrea, Susan E, additional

Published
2024
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46. Search for sterile neutrinos in MINOS and MINOS+ using a two-detector fit

Author

Adamson, P., Anghel, I., Aurisano, A., Barr, G., Bishai, M., Blake, A., Bock, G. J., Bogert, D., Cao, S. V., Carroll, T. J., Castromonte, C. M., Chen, R., Childress, S., Coelho, J. A. B., Corwin, L., Cronin-Hennessy, D., de Jong, J. K., De Rijck, S., Devan, A. V., Devenish, N. E., Diwan, M. V., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Flanagan, W., Frohne, M. V., Gabrielyan, M., Gallagher, H. R., Germani, S., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grzelak, K., Habig, A., Hahn, S. R., Hartnell, J., Hatcher, R., Holin, A., Huang, J., Hylen, J., Irwin, G. M., Isvan, Z., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koerner, L. W., Koizumi, G., Kordosky, M., Kreymer, A., Lang, K., Ling, J., Litchfield, P. J., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGivern, C., Medeiros, M. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Miller, W. H., Mishra, S. R., Sher, S. Moed, Moore, C. D., Mualem, L., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nowak, J. A., O'Connor, J., Orchanian, M., Pahlka, R. B., Paley, J., Patterson, R. B., Pawloski, G., Perch, A., Pfützner, M. M., Phan, D. D., Phan-Budd, S., Plunkett, R. K., Poonthottathil, N., Qiu, X., Radovic, A., Rebel, B., Rosenfeld, C., Rubin, H. A., Sail, P., Sanchez, M. C., Schneps, J., Schreckenberger, A., Schreiner, P., Sharma, R., Sousa, A., Tagg, N., Talaga, R. L., Thomas, J., Thomson, M. A., Tian, X., Timmons, A., Todd, J., Tognini, S. C., Toner, R., Torretta, D., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R. C., White, C., Whitehead, L. H., Wojcicki, S. G., and Zwaska, R.

Subjects
High Energy Physics - Experiment
Abstract

A search for mixing between active neutrinos and light sterile neutrinos has been performed by looking for muon neutrino disappearance in two detectors at baselines of 1.04 km and 735 km, using a combined MINOS and MINOS+ exposure of $16.36\times10^{20}$ protons-on-target. A simultaneous fit to the charged-current muon neutrino and neutral-current neutrino energy spectra in the two detectors yields no evidence for sterile neutrino mixing using a 3+1 model. The most stringent limit to date is set on the mixing parameter $\sin^2\theta_{24}$ for most values of the sterile neutrino mass-splitting $\Delta m^2_{41} > 10^{-4}$ eV$^2$., Comment: 7 pages, 4 figures, additional analysis details and a data release in the ancillary materials

Published
2017
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