Search

Your search keyword '"Obata-Yasuoka, Mana"' showing total 42 results
Start Over Author "Obata-Yasuoka, Mana"
42 results on '"Obata-Yasuoka, Mana"'

1. Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions via the TGFb/Smad2-3 Signaling Pathway

Author

Vuong, Cat-Khanh, primary, Fukushige, Mizuho, additional, Ngo, Nhat-Hoang, additional, Yamashita, Toshiharu, additional, Obata-Yasuoka, Mana, additional, Hamada, Hiromi, additional, Osaka, Motoo, additional, Tsukada, Toru, additional, Hiramatsu, Yuji, additional, and Ohneda, Osamu, additional

Published
2024
Full Text
View/download PDF

3. Extracellular vesicles derived from SARS-CoV-2 M-protein-induced triple negative breast cancer cells promoted the ability of tissue stem cells supporting cancer progression

Author

Nguyen, Hoai-Nga Thi, primary, Vuong, Cat-Khanh, additional, Fukushige, Mizuho, additional, Usuda, Momoko, additional, Takagi, Liora Kaho, additional, Yamashita, Toshiharu, additional, Obata-Yasuoka, Mana, additional, Hamada, Hiromi, additional, Osaka, Motoo, additional, Tsukada, Toru, additional, Hiramatsu, Yuji, additional, and Ohneda, Osamu, additional

Published
2024
Full Text
View/download PDF

6. Guidelines for obstetrical practice in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2020 edition

Author

Atsuo Itakura, Satoh Shoji, Aoki Shigeru, Fukushima Kotaro, Hasegawa Junichi, Hyodo Hironobu, Yoshimasa Kamei, Kondoh Eiji, Makino Shintaro, Matsuoka Ryu, Morikawa Mamoru, Nagamatsu Takeshi, Nakata Masahiko, Katsuhiko Naruse, Nishigori Hidekazu, Nishiguchi Tomizo, Obata‐Yasuoka Mana, Ohno Yasumasa, Oura Kuniaki, Shimoya Koichiro, Shiozaki Arihiro, Suzuki Shunji, Tanaka Kanji, Yoshida Shiro, Kudo Yoshiki, Maeda Tsugio, and Shozu Makio

Subjects
Obstetrics and Gynecology
Abstract

The 2017 clinical guidelines for obstetrical practice by the Japan Society of Obstetrics and Gynecology and the Japan Association of Obstetricians and Gynecologists were revised and published as the 2020 edition (in Japanese). The aim of these guidelines is to present appropriate standard obstetric diagnosis and management procedures that have reached consensus among Japanese obstetricians. The 2020 guidelines include 113 clinical questions and an appendix, followed by answers (CQA; originally 112 in the 2017 edition), a discussion, list of references, and some tables and figures presenting common problems and questions encountered in obstetrical practice. Each answer comes with a recommendation level of A, B, or C and has been prepared based principally on evidence or a consensus among Japanese obstetricians in situations where "evidence" is weak or lacking. Answers with a recommendation level of A or B represent current standard care practices in Japan. All 113 CQAs and the appendix are presented here to promote a better understanding of the current standard care practices for pregnant and lactating women in Japan.

Published
2022

11. Obstetric venous thromboembolism: Evaluation of prophylactic approach based on risk scores, D‐dimer levels, and ultrasonography findings in a tertiary hospital in Japan

Author

Obata‐Yasuoka, Mana, primary, Ohara, Rena, additional, Hosokawa, Yoshihiko, additional, Nishida, Keiko, additional, Abe, Haruna, additional, Mayumi, Miyuki, additional, Ishizu, Tomoko, additional, Endo‐Kawamura, Naho, additional, Hamada, Hiromi, additional, and Satoh, Toyomi, additional

Published
2022
Full Text
View/download PDF

12. Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions

Author

Khanh, Vuong Cat, primary, Fukushige, Mizuho, additional, Chang, Yun Hsuan, additional, Hoang, Ngo Nhat, additional, Yamashita, Toshiharu, additional, Obata-Yasuoka, Mana, additional, Hamada, Hiromi, additional, Osaka, Motoo, additional, Hiramatsu, Yuji, additional, and Ohneda, Osamu, additional

Published
2021
Full Text
View/download PDF

13. Rectoperineal Fistula Presented 5 Months After Repair of Severe Obstetric Perineal Laceration: A Case Report

Author

Ohara, Yusuke, primary, Enomoto, Tsuyoshi, additional, Owada, Yohei, additional, Hisakura, Katsuji, additional, Akashi, Yoshimasa, additional, Ogawa, Koichi, additional, Doi, Manami, additional, Takahashi, Kazuhiro, additional, Shimomura, Osamu, additional, Furuya, Kinji, additional, Kim, Jaejeong, additional, Hashimoto, Shinji, additional, Ohara, Rena, additional, Obata-Yasuoka, Mana, additional, Hamada, Hiromi, additional, and Oda, Tatsuya, additional

Published
2021
Full Text
View/download PDF

16. Pelvic arterial embolisation with cyanoacrylate during caesarean hysterectomy for placenta accreta.

Author

Mori, Kensaku, Obata-Yasuoka, Mana, Saida, Tsukasa, Nishida, Keiko, Takahashi, Hiroaki, Hosokawa, Yoshihiko, Takei, Yohei, Tsumagari, Ayako, Yoshida, Miki, Kimura, Yutaku, Abe, Tetsuya, Tsukuda, Yoko, Harada, Shu, Kojima, Takahiro, and Minami, Manabu

Subjects
*MAGNETIC resonance angiography, *HYSTERECTOMY, *THERAPEUTIC embolization, *RETROSPECTIVE studies, *PLACENTA accreta, *DESCRIPTIVE statistics, *CESAREAN section, *UTERINE artery
Abstract

To compare n-butyl cyanoacrylate (NBCA) and gelatine sponge (GS) as embolic materials for prophylactic pelvic arterial embolisation during caesarean hysterectomy for placenta accreta spectrum (PAS). This retrospective study comprised 12 women (age range, 23–42 years; mean, 34.1 years) who underwent caesarean hysterectomy for PAS. Following caesarean delivery, bilateral uterine and non-uterine parasitic arteries were embolized with GS in the first four cases (GS group) and primarily with NBCA mixed with iodized oil in the subsequent eight cases (NBCA group). Procedure time for embolisation and hysterectomy and total blood loss were compared between the two groups using Welch's t-test. Although procedure time for embolisation tended to be longer in the NBCA group than in the GS group (111 ± 47 min versus 71 ± 32 min, p=.11), that for hysterectomy was significantly reduced in the NBCA group when compared to the GS group (158 ± 42 min versus 236 ± 39 min, p=.02). Total blood loss was significantly lower in the NBCA group than in the GS group (1375 ± 565 mL versus 2668 ± 587 mL, p=.01). Procedure time for hysterectomy and total blood loss during caesarean hysterectomy can be reduced by using NBCA instead of GS in prophylactic pelvic arterial embolisation for PAS. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

17. Vaginal Escherichia coli share common virulence factor profiles, serotypes and phylogeny with other extraintestinal E. coli

Author

Obata-Yasuoka, Mana, Ba-Thien, William, Tsukamoto, Teizo, Yoshikawa, Hiroyuki, and Hayashi, Hideo

Subjects
Microbiological research -- Analysis, Escherichia coli -- Genetic aspects, Antigens -- Physiological aspects, Phylogeny -- Genetic aspects, Virulence (Microbiology) -- Genetic aspects, Biological sciences
Abstract

Research has been conducted on vaginal Escherichia coli. The characterization of E. coli isolates has been carried out via the extraintestinal virulence factor profiling, such as phylogenetic analysis and O:H serotyping and the results are reported.

Published
2002

20. Pelvic arterial embolisation with cyanoacrylate during caesarean hysterectomy for placenta accreta

Author

Mori, Kensaku, primary, Obata-Yasuoka, Mana, additional, Saida, Tsukasa, additional, Nishida, Keiko, additional, Takahashi, Hiroaki, additional, Hosokawa, Yoshihiko, additional, Takei, Yohei, additional, Tsumagari, Ayako, additional, Yoshida, Miki, additional, Kimura, Yutaku, additional, Abe, Tetsuya, additional, Tsukuda, Yoko, additional, Harada, Shu, additional, Kojima, Takahiro, additional, and Minami, Manabu, additional

Published
2020
Full Text
View/download PDF

22. Antithrombin deficiency in pregnancy

Author

Morikawa, Mamoru, Suzuki, Hirotada, Obata-Yasuoka, Mana, Kasai, Michi, Itoh, Hiroaki, Ohkuchi, Akihide, Hamada, Hiromi, Aoki, Shigeru, Kanayama, Naohiro, and Minakami, Hisanori

Subjects
acute fatty liver of pregnancy, antithrombin activity, maternal mortality, pregnancy complication, HELLP syndrome, disseminated intravascular coagulation
Abstract

Background and Aim: Liver dysfunction with decreased antithrombin activity (AT) and/or thrombocytopenia is life-threatening in pregnant women. Whether AT is clinically useful for prediction of liver dysfunction remains unclear. Methods: A total of 541 women were registered prospectively at gestational week 34.7 (20.0 - 41.4) with available data on antenatal AT and platelet count (PLC). Results: Liver dysfunction defined as serum AST > 45 IU/L concomitant with lactate dehydrogenase (LDH) > 400 IU/L occurred in five women antenatally (≤ 2 weeks before delivery) and in 17 women postpartum (within 1 week postpartum). Median (5th - 95th) antenatal value was 85 (62 - 110)% for AT and 202 (118 - 315)×10^9/L for PLC in the 541 women, and was significantly lower in women with than without perinatal liver dysfunction; 75 (51 - 108) vs. 86 (62 - 110)% and 179 (56 - 244) vs. 203 (121 - 316)×10^9/L, respectively. Nineteen (86%) women with liver dysfunction showed AT ≤ 62% or thrombocytopenia (PLC ≤ 118×10^9/L) perinatally, but five lacked thrombocytopenia throughout the perinatal period. The best cut-off (AT, 77%; PLC, 139×10^9/L) suggested by receiver operating characteristic curve gave antenatal AT and PLC sensitivity of 59% and 41% with positive predictive value (PPV) of 8.6% and 14%, respectively, and combined use of AT and PLC improved sensitivity to 73% (16/22) with PPV of 9.2% for prediction of perinatal liver dysfunction. Conclusions: Reduced AT not accompanied by thrombocytopenia can precede liver dysfunction. Clinical introduction of AT may enhance safety of pregnant women.

Published
2017

28. Isolated gestational proteinuria preceding the diagnosis of preeclampsia - an observational study

Author

Yamada, Takahiro, primary, Obata-Yasuoka, Mana, additional, Hamada, Hiromi, additional, Baba, Yosuke, additional, Ohkuchi, Akihide, additional, Yasuda, Shun, additional, Kawabata, Kosuke, additional, Minakawa, Shiori, additional, Hirai, Chihiro, additional, Kusaka, Hideto, additional, Murabayashi, Nao, additional, Inde, Yusuke, additional, Nagura, Michikazu, additional, Umazume, Takeshi, additional, Itakura, Atsuo, additional, Maeda, Makoto, additional, Sagawa, Norimasa, additional, Ohno, Yasumasa, additional, Kataoka, Soromon, additional, Fujimori, Keiya, additional, Kudo, Yoshiki, additional, Ikeda, Tomoaki, additional, Nakai, Akihito, additional, and Minakami, Hisanori, additional

Published
2016
Full Text
View/download PDF

30. Urinary protein-to-creatinine ratio in pregnant women after dipstick testing: prospective observational study

Author

Baba, Yosuke, primary, Yamada, Takahiro, additional, Obata-Yasuoka, Mana, additional, Yasuda, Shun, additional, Ohno, Yasumasa, additional, Kawabata, Kosuke, additional, Minakawa, Shiori, additional, Hirai, Chihiro, additional, Kusaka, Hideto, additional, Murabayashi, Nao, additional, Inde, Yusuke, additional, Nagura, Michikazu, additional, Hamada, Hiromi, additional, Itakura, Atsuo, additional, Ohkuchi, Akihide, additional, Maeda, Makoto, additional, Sagawa, Norimasa, additional, Nakai, Akihito, additional, Kataoka, Soromon, additional, Fujimori, Keiya, additional, Kudo, Yoshiki, additional, Ikeda, Tomoaki, additional, and Minakami, Hisanori, additional

Published
2015
Full Text
View/download PDF

33. Associations Between Multidrug Resistance, Plasmid Content, and Virulence Potential Among Extraintestinal Pathogenic and CommensalEscherichia colifrom Humans and Poultry

Author

Johnson, Timothy J., primary, Logue, Catherine M., additional, Johnson, James R., additional, Kuskowski, Michael A., additional, Sherwood, Julie S., additional, Barnes, H. John, additional, DebRoy, Chitrita, additional, Wannemuehler, Yvonne M., additional, Obata-Yasuoka, Mana, additional, Spanjaard, Lodewijk, additional, and Nolan, Lisa K., additional

Published
2012
Full Text
View/download PDF

35. Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli

Author

Weissman, Scott J., primary, Chattopadhyay, Sujay, additional, Aprikian, Pavel, additional, Obata‐Yasuoka, Mana, additional, Yarova‐Yarovaya, Yuliya, additional, Stapleton, Ann, additional, Ba‐Thein, William, additional, Dykhuizen, Daniel, additional, Johnson, James R., additional, and Sokurenko, Evgeni V., additional

Published
2005
Full Text
View/download PDF

39. Type 1, P and S fimbriae, and afimbrial adhesin I are not essential for uropathogenic Escherichia coli to adhere to and invade bladder epithelial cells

Author

Miyazaki, Jun, Ba-Thein, William, Kumao, Toshio, Obata Yasuoka, Mana, Akaza, Hideyuki, and Hayshi, Hideo

Subjects
PILI (Microbiology), ESCHERICHIA coli, MICROBIAL virulence
Abstract

Fimbrial (type 1, P, and S) and afimbrial adhesins, the unique virulence traits of uropathogenic Escherichia coli (UPEC), are well recognized for their role in the initial step of uropathogenesis. In this study, we investigated whether these adhesins are dispensable for UPEC in adherence and invasion of uroepithelial cells by using E. coli isolates (n=40) from cystitis patients and T-24 cells, the bladder carcinoma cell line. We found all isolates adherent to T-24 cells within 15 min of infection. In invasion assay, all isolates could invade T-24 cells to a variable degree; 22.5% of them were found highly invasive. About 33% of isolates that do not have any recognized adhesins were as invasive as other isolates. The amplitude of invasiveness was also independent of the adhesins. In conclusion, this study demonstrates that type 1 fimbriae, P fimbriae, S fimbriae, and afimbrial adhesin I are not required for UPEC to adhere to and invade uroepithelial cells. [Copyright &y& Elsevier]

Published
2002
Full Text
View/download PDF

40. Associations Between Multidrug Resistance, Plasmid Content, and Virulence Potential Among Extraintestinal Pathogenic and Commensal Escherichia colifrom Humans and Poultry

Author

Johnson, Timothy J., Logue, Catherine M., Johnson, James R., Kuskowski, Michael A., Sherwood, Julie S., Barnes, H. John, DebRoy, Chitrita, Wannemuehler, Yvonne M., Obata-Yasuoka, Mana, Spanjaard, Lodewijk, and Nolan, Lisa K.

Abstract

AbstractThe emergence of plasmid-mediated multidrug resistance (MDR) among enteric bacteria presents a serious challenge to the treatment of bacterial infections in humans and animals. Recent studies suggest that avian Escherichia colicommonly possess the ability to resist multiple antimicrobial agents, and might serve as reservoirs of MDR for human extraintestinal pathogenic Escherichia coli(ExPEC) and commensal E. colipopulations. We determined antimicrobial susceptibility profiles for 2202 human and avian E. coliisolates, then sought for associations among resistance profile, plasmid content, virulence factor profile, and phylogenetic group. Avian-source isolates harbored greater proportions of MDR than their human counterparts, and avian ExPEC had higher proportions of MDR than did avian commensal E. coli. MDR was significantly associated with possession of the IncA/C, IncP1-α, IncF, and IncI1 plasmid types. Overall, inferred virulence potential did not correlate with drug susceptibility phenotype. However, certain virulence genes were positively associated with MDR, including ireA, ibeA, fyuA, cvaC, iss, iutA, iha, and afa. According to the total dataset, isolates segregated significantly according to host species and clinical status, thus suggesting that avian and human ExPEC and commensal E. colirepresent four distinct populations with limited overlap. These findings suggest that in extraintestinal E. coli, MDR is most commonly associated with plasmids, and that these plasmids are frequently found among avian-source E. colifrom poultry production systems.

Published
2012
Full Text
View/download PDF

41. Pharmacokinetic study of erlotinib in a pregnant woman with advanced non‐small cell lung cancer and observation of the effects on the child growth.

Author

Aida, Yuka, Ohgami, Masahiro, Mukai, Yuji, Matsuyama, Masashi, Obata‐Yasuoka, Mana, Satoh, Toyomi, Homma, Masato, Sekine, Ikuo, and Hizawa, Nobuyuki

Abstract

Aims Methods Results Conclusion The aim of the study is to report the clinical and pharmacological observations from a pregnant patient treated with erlotinib in the second and third trimesters of pregnancy.Maternal and neonatal blood levels and safety of erlotinib and its metabolites were evaluated. Child development was monitored for 6 years.A 31‐year‐old woman with stage IV lung adenocarcinoma with EGFR exon19 deletion began treatment with erlotinib 150 mg/day at 17 weeks of gestation. Although foetal growth retardation and oligohydramnios were observed at several times during the pregnancy, treatment was continued due to the severity of the maternal presentation, with ongoing foetal monitoring. The foetus seemed to tolerate and recover well without specific interventions. A healthy baby boy was delivered at 37 weeks gestation. The child grew and developed without any obvious issues. At last follow‐up, at age 6 years, he was attending school at a grade appropriate for his age without health or developmental problems. Blood levels of erlotinib were 397–856 ng/mL at 18–37 weeks of gestation and 1190 ng/mL at 8 weeks postpartum. The blood concentration ratios of OSI‐413‐to‐erlotinib ranged from 0.167 to 0.253 at 18–37 weeks of gestation, excluding 24 weeks, and 0.131 at 8 weeks postpartum. The maternal‐to‐foetal transfer rate of erlotinib, OSI‐420 and OSI‐413 were 24.5, 34.8 and 20.3%, respectively.Erlotinib use during the second and third trimester of pregnancy did not seem to cause any untoward effects on the developing foetus, or any long‐lasting effects that could be detected during 6 years of follow‐up of the child. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

42. Associations between multidrug resistance, plasmid content, and virulence potential among extraintestinal pathogenic and commensal Escherichia coli from humans and poultry.

Author

Johnson TJ, Logue CM, Johnson JR, Kuskowski MA, Sherwood JS, Barnes HJ, DebRoy C, Wannemuehler YM, Obata-Yasuoka M, Spanjaard L, and Nolan LK

Subjects
Animals, Chickens, DNA, Bacterial genetics, Escherichia coli drug effects, Escherichia coli isolation & purification, Escherichia coli pathogenicity, Feces microbiology, Female, Genotype, Humans, Infant, Newborn, Meat microbiology, Microbial Sensitivity Tests, Phylogeny, Replicon genetics, Turkeys, Virulence Factors genetics, Anti-Infective Agents pharmacology, Drug Resistance, Multiple, Bacterial genetics, Escherichia coli genetics, Escherichia coli Infections microbiology, Plasmids genetics, Poultry Diseases microbiology
Abstract

The emergence of plasmid-mediated multidrug resistance (MDR) among enteric bacteria presents a serious challenge to the treatment of bacterial infections in humans and animals. Recent studies suggest that avian Escherichia coli commonly possess the ability to resist multiple antimicrobial agents, and might serve as reservoirs of MDR for human extraintestinal pathogenic Escherichia coli (ExPEC) and commensal E. coli populations. We determined antimicrobial susceptibility profiles for 2202 human and avian E. coli isolates, then sought for associations among resistance profile, plasmid content, virulence factor profile, and phylogenetic group. Avian-source isolates harbored greater proportions of MDR than their human counterparts, and avian ExPEC had higher proportions of MDR than did avian commensal E. coli. MDR was significantly associated with possession of the IncA/C, IncP1-α, IncF, and IncI1 plasmid types. Overall, inferred virulence potential did not correlate with drug susceptibility phenotype. However, certain virulence genes were positively associated with MDR, including ireA, ibeA, fyuA, cvaC, iss, iutA, iha, and afa. According to the total dataset, isolates segregated significantly according to host species and clinical status, thus suggesting that avian and human ExPEC and commensal E. coli represent four distinct populations with limited overlap. These findings suggest that in extraintestinal E. coli, MDR is most commonly associated with plasmids, and that these plasmids are frequently found among avian-source E. coli from poultry production systems.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results