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4. Hypoglycaemic activity of Ocimum gratissimum in rats.

Author

Aguiyi JC, Obi CI, Gang SS, and Igweh AC

Subjects
Alloxan, Animals, Blood Glucose drug effects, Disease Models, Animal, Hypoglycemic Agents therapeutic use, Male, Medicine, African Traditional, Phytotherapy, Plant Extracts pharmacology, Plant Leaves, Rats, Rats, Wistar, Diabetes Mellitus drug therapy, Diabetes Mellitus, Experimental, Hypoglycemic Agents pharmacology, Ocimum basilicum, Plants, Medicinal
Abstract

The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68%, respectively.

Published
2000
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