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1. Clinical Phenotype of Musladin-Lueke Syndrome in 2 Beagles.

Author

Packer, R, Logan, M, Guo, L, Apte, S, Bader, H, OBrien, D, Johnson, G, and Shelton, G

Subjects
ADAMTSL2, Chinese Beagle syndrome, ballerina Beagle syndrome, geleophysic dysplasiacanine, Animals, Bone Diseases, Developmental, Dog Diseases, Dogs, Female, Humans, Joint Diseases, Limb Deformities, Congenital, Male, Mice, Phenotype, Skin Abnormalities
Abstract

Musladin-Lueke syndrome (MLS), previously termed Chinese Beagle syndrome, is an autosomal-recessive connective tissue disorder characterized by extensive fibrosis of the skin and joints that was first identified in Beagles in the 1970s. Recent research identified a founder mutation (c.660C>T; p.R221C) in the ADAMTSL2 gene in Beagles with MLS. Here, we report the detailed clinical phenotype and laboratory findings in 2 Beagles affected with MLS. We discuss these findings in relation to the human disorder geleophysic dysplasia (GD), which also arises from recessive ADAMTSL2 mutations, and recent findings in Adamtsl2-deficient mice.

Published
2017

2. Nature of the 'Orange' Material on Vesta From Dawn

Author

LeCorre, L, Reddy, V, Schmedemann, N, Becker, K. J, OBrien, D. P, Yamashita, N, Peplowski, P. N, Prettyman, T. H, Li, J.-Y, Coultis, E. A, Denevi, B. W, Kneissl, T, Palmer, E, Gaskell, R. W, Nathues, A, Gaffey, M. J, Mittlefeldt, D. W, Gary, W. B, Sierks, H, Russell, C. T, and Raymond, C. A

Subjects
Lunar And Planetary Science And Exploration
Abstract

From ground-based observations of Vesta, it is well-known that the vestan surface has a large variation in albedo. Analysis of images acquired by the Hubble Space Telescope allowed production of the first color maps of Vesta and showed a diverse surface in terms of reflectance. Thanks to images collected by the Dawn spacecraft at Vesta, it became obvious that these specific units observed previously can be linked to geological features. The presence of the darkest material mostly around impact craters and scattered in the Western hemisphere has been associated with carbonaceous chondrite contamination [4]; whereas the brightest materials are believed to result from exposure of unaltered material from the subsurface of Vesta (in fresh looking impact crater rims and in Rheasilvia's ejecta and rim remants). Here we focus on a distinct material characterized by a steep slope in the near-IR relative to all other kinds of materials found on Vesta. It was first detected when combining Dawn Framing Camera (FC) color images in Clementine false-color composites [5] during the Approach phase of the mission (100000 to 5200 km from Vesta). We investigate the mineralogical and elemental composition of this material and its relationship with the HEDs (Howardite-Eucrite- Diogenite group of meteorites).

Published
2014

3. Origin of Dark Material on VESTA from DAWN FC Data: Remnant Carbonaceous Chondrite Impators

Author

Reddy, V, LeCorre, L, Nathues, A, Mittlefehldt, David W, Cloutis, E. A, OBrien, D. P, Durda, D. D, Bottke, W. F, Buczkowski, D, Scully, J. E. C, Palmer, E. M, Sierks, H, Mann, P. J, Becker, K. J, Beck, A. W, Li, Y-Y, Gaskell, R, Russell, C. T, Gaffey, M. J, McSween, H. Y, McCord, T. B, Combe, J.-P, and Blewett, D

Subjects
Lunar And Planetary Science And Exploration
Abstract

NASA's Dawn spacecraft entered orbit around asteroid (4) Vesta in July 2011 for a yearlong mapping orbit. The surface of Vesta as imaged by the Dawn Framing Camera (FC) revealed a surface that is unlike any asteroid we have visited so far with a spacecraft. Albedo and color variations on Vesta are the most diverse in the asteroid belt with a majority of these linked to distinct compositional units on the asteroid s surface. FC discovered dark material on Vesta. These low albedo surface features were first observed during Rotational Characterization 3 phase at a resolution of approx. 487 m/pixel. Here we explore the composition and possible meteoritical analogs for the dark material on Vesta.

Published
2012

4. Does Vesta Have Moons?: Dawn's Search for Satellites

Author

McFadden, L. A, Sykes, M. V, Tricarico, P, Carsenty, U, Gutierrez-Marques, P, Jacobson, R. A, Joy, S, Keller, H. U, Li, J.-Y, McLean, B, Memarsadeghi, N, Mottola, S, Mutchler, M, Nathues, A, OBrien, D, Palmer, E, Polanskey, C, Sierks, H, Rayman, M. D, Raymond, C. A, Russell, C. T, Schroeder, S, Skillman, D, and Weinstein-Weiss, S

Subjects
Astronomy
Abstract

Upon approach to asteroid 4 Vesta, the Dawn mission included a dedicated satellite search observation of the operational sphere of the spacecraft around Vesta. Discovery of moons of Vesta would constrain theories of satellite f()rmation. The sequence using the framing camera and clear filter includes three mosaics of six stations acquired on July 9-10. 2011. Each station consists of four sets with three different exposures, 1.5,20 and 270 s. We also processed and scanned the optical navigation sequences until Vesta filled the field of view. Analysis of images involves looking for moving objects in the mosaics and identifying catalogued stars, subtracting them from the image and examining residual objects for evidence of bodies in orbit around Vesta. Celestial coordinates were determined using Astrometry.net, an astrometry calibration service (http://astrometry.net/use.html). We processed the images by subtracting dark and bias fields and dividing by a Hatfield. Images were further filtered subtracting a box car filter (9x9 average) to remove effects of scattered light from Vesta itself. Images were scanned by eye for evidence of motion in directions different from the background stars. All objects were compared with Hubble Space Telescope's Guide Star Catalogue and US Naval Observatory's UCAC3 catalog. We report findings from these observations and analysis, including limits of magnitude, size and motion of objects in orbit around Vesta. We gratefully acknowledge modifications made to Astrometrica http://www.astrometrica.at/ for purposes of this effort.

Published
2011

5. The Impact History of Vesta: New Views from the Dawn Mission

Author

OBrien, D. P, Marchi, S, Schenk, P, Mittlefehldt, D. W, Jaumann, R, Ammannito, E, Buczkowski, D. L, DeSanctis, M. C, Filacchione, G, Gaskell, R, Hoffmann, M, Joy, S, LeCorre, L, Li, Y.-Y, Nathunes, A, Polanskey, C, Preusker, F, Rayman, M, Raymond, C. A, Reddy, V, Roatsch, T, Russell, C. T, Turrini, D, and Vincent. J.-B

Subjects
Astrophysics
Abstract

The Dawn mission has completed its Survey and High-Altitude Mapping Orbit (HAMO) phases at Vesta, resulting in 60-70 meter per pixel imaging, high-resolution image-derived topography, and visual and infrared spectral data covering up to approx.50 degrees north latitude (the north pole was in shadow during these mission phases). These data have provided unprecedented views of the south polar impact structure first detected in HST imaging [1], now named Rheasilvia, and in addition hint at the existence of a population of ancient basins. Smaller craters are seen at all stages from fresh to highly-eroded, with some exposing atypically bright or dark material. The morphology of some craters has been strongly influenced by regional slope. Detailed studies of crater morphology are underway. We have begun making crater counts to constrain the relative ages of different regions of the surface, and are working towards developing an absolute cratering chronology for Vesta's surface.

Published
2011

6. Introduction

Author

FAFRAK, S, primary, LOLA, J, additional, OBRIEN, D, additional, YATES, G, additional, and NICHOLS, B, additional

Published
2003
Full Text
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9. Resources

Author

FAFRAK, S, primary, LOLA, J, additional, OBRIEN, D, additional, YATES, G, additional, and NICHOLS, B, additional

Published
2003
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15. International preoperative rectal cancer management: staging, neoadjuvant treatment, and impact of multidisciplinary teams

Author

Augestad KM, Lindsetmo RO, Stulberg J, Reynolds H, Senagore A, Champagne B, Heriot AG, Leblanc F, Delaney CP, Ambrosetti P, Andujar J, Baixuli J, Balen E, Baxter N, Beck D, Bemelman W, Bergamaschi R, Billingham R, Birch D, Bonardi R, Bonardi M, Bonjer J, Braga M, Buch H, Buechler M, Burnstein M, Campbell K, Caushaj P, Celebrezze J, Chang G, Cheong D, Cohen J, Colak T, Delaney C, Dhoore A, Douglas P, Dozois E, Efron J, Ellis N, Enker W, Fanelli RD, Fazio V, Fleshman J, Franklin M, Fry R, Garcia Aguilar J, Garcia Granero E, Habr Gama A, Hahnloser D, Harris G, Hasegawa H, Holm T, Horgan P, Hyman N, Irwin T, Joh YG, Jongen J, Kaiser A, Kang SB, Kariv Y, Kennedy R, Kessler H, Khan M, Kim SH, Krokowicz P, Kwok S, Lacy A, Larson D, Law WL, Lee E, Lippert H, Ludwig K, Lynch AC, MacRae H, Madbouly K, Maeda K, Marderstein E, Marino M, Marks J, Maurer C, McLeod R, Monson J, Mortensen N, Neary P, Newstead G, OBrien D, Orangio G, Orkin B, Page M, Påhlman L, Panis Y, Panton N, Pennickx F, Phang T, Pinedo Mancilla G, Post S, Rafferty J, Rajput A, Reis Neto dos JA, Rivadeneira D, Roselli J, Rosen H, Rossi G, Rouanet P, Rullier E, Schiedeck T, Schiessel R, Schlachta C, Schwenk W, Seow Choen F, Sim R, Sing WK, Stamos M, Sternberg J, Tuckson W, Vaccaro C, Vargas D, Vignali A, Vonen B, Weiss E, Wexner S, Whiteford M, Wibe A, Williams N, Woods R, Yamamoto T, Young Fadok T., UGOLINI, GIAMPAOLO, Augestad KM, Lindsetmo RO, Stulberg J, Reynolds H, Senagore A, Champagne B, Heriot AG, Leblanc F, Delaney CP, Ambrosetti P, Andujar J, Baixuli J, Balen E, Baxter N, Beck D, Bemelman W, Bergamaschi R, Billingham R, Birch D, Bonardi R, Bonardi M, Bonjer J, Braga M, Buch H, Buechler M, Burnstein M, Campbell K, Caushaj P, Celebrezze J, Chang G, Cheong D, Cohen J, Colak T, Delaney C, Dhoore A, Douglas P, Dozois E, Efron J, Ellis N, Enker W, Fanelli RD, Fazio V, Fleshman J, Franklin M, Fry R, Garcia-Aguilar J, Garcia-Granero E, Habr-Gama A, Hahnloser D, Harris G, Hasegawa H, Holm T, Horgan P, Hyman N, Irwin T, Joh YG, Jongen J, Kaiser A, Kang SB, Kariv Y, Kennedy R, Kessler H, Khan M, Kim SH, Krokowicz P, Kwok S, Lacy A, Larson D, Law WL, Lee E, Lippert H, Ludwig K, Lynch AC, MacRae H, Madbouly K, Maeda K, Marderstein E, Marino M, Marks J, Maurer C, McLeod R, Monson J, Mortensen N, Neary P, Newstead G, OBrien D, Orangio G, Orkin B, Page M, Påhlman L, Panis Y, Panton N, Pennickx F, Phang T, Pinedo Mancilla G, Post S, Rafferty J, Rajput A, Reis Neto dos JA, Rivadeneira D, Roselli J, Rosen H, Rossi G, Rouanet P, Rullier E, Schiedeck T, Schiessel R, Schlachta C, Schwenk W, Seow-Choen F, Sim R, Sing WK, Stamos M, Sternberg J, Tuckson W, Ugolini G, Vaccaro C, Vargas D, Vignali A, Vonen B, Weiss E, Wexner S, Whiteford M, Wibe A, Williams N, Woods R, Yamamoto T, Young-Fadok T., Augestad, K, Lindsetmo, R, Stulberg, J, Reynolds, H, Senagore, A, Champagne, B, Heriot, A, Leblanc, F, Delaney, C, Ambrosetti, P, Andujar, J, Baixuli, J, Balen, E, Baxter, N, Beck, D, Bemelman, W, Bergamaschi, R, Billingham, R, Birch, D, Bonardi, R, Bonardi, M, Bonjer, J, Braga, M, Buch, H, Buechler, M, Burnstein, M, Campbell, K, Caushaj, P, Celebrezze, J, Chang, G, Cheong, D, Cohen, J, Colak, T, Dhoore, A, Douglas, P, Dozois, E, Efron, J, Ellis, N, Enker, W, Fanelli, R, Fazio, V, Fleshman, J, Franklin, M, Fry, R, Garcia-Aguilar, J, Garcia-Granero, E, Habr-Gama, A, Hahnloser, D, Harris, G, Hasegawa, H, Holm, T, Horgan, P, Hyman, N, Irwin, T, Joh, Y, Jongen, J, Kaiser, A, Kang, S, Kariv, Y, Kennedy, R, Kessler, H, Khan, M, Kim, S, Krokowicz, P, Kwok, S, Lacy, A, Larson, D, Law, W, Lee, E, Lippert, H, Ludwig, K, Lynch, A, Macrae, H, Madbouly, K, Maeda, K, Marderstein, E, Marino, M, Marks, J, Maurer, C, Mcleod, R, Monson, J, Mortensen, N, Neary, P, Newstead, G, Obrien, D, Orangio, G, Orkin, B, Page, M, Pahlman, L, Panis, Y, Panton, N, Pennickx, F, Phang, T, Pinedo Mancilla, G, Post, S, Rafferty, J, Rajput, A, Reis Neto dos, J, Rivadeneira, D, Roselli, J, Rosen, H, Rossi, G, Rouanet, P, Rullier, E, Schiedeck, T, Schiessel, R, Schlachta, C, Schwenk, W, Seow-Choen, F, Sim, R, Sing, W, Stamos, M, Sternberg, J, Tuckson, W, Ugolini, G, Vaccaro, C, Vargas, D, Vignali, A, Vonen, B, Weiss, E, Wexner, S, Whiteford, M, Wibe, A, Williams, N, Woods, R, Yamamoto, T, and Young-Fadok, T

Subjects
medicine.medical_specialty, Internationality, Colorectal cancer, health care facilities, manpower, and services, medicine.medical_treatment, education, Preoperative care, Article, RECTAL CANCER, COLORECTAL SURGERY, Preoperative Care, MANAGEMENT, Medicine, Humans, Stage (cooking), health care economics and organizations, Neoadjuvant therapy, Neoplasm Staging, Patient Care Team, Rectal Neoplasm, medicine.diagnostic_test, business.industry, Rectal Neoplasms, General surgery, Cancer, Rectal examination, Vascular surgery, medicine.disease, humanities, Neoadjuvant Therapy, Surgery, Treatment Outcome, Health Care Survey, Health Care Surveys, Practice Guidelines as Topic, MULTIDISCIPLINARY TEAMS, Rectal Neoplasms - pathology - surgery - therapy, business, Human, Abdominal surgery
Abstract

Law, WL is one of the members of the International Rectal Cancer Study Group, BACKGROUND: Little is known regarding variations in preoperative treatment and practice for rectal cancer (RC) on an international level, yet practice variation may result in differences in recurrence and survival rates. METHODS: One hundred seventy-three international colorectal centers were invited to participate in a survey of preoperative management of rectal cancer. RESULTS: One hundred twenty-three (71%) responded, with a majority of respondents from North America, Europe, and Asia. Ninety-three percent have more than 5 years' experience with rectal cancer surgery. Fifty-five percent use CT scan, 35% MRI, 29% ERUS, 12% digital rectal examination and 1% PET scan in all RC cases. Seventy-four percent consider threatened circumferential margin (CRM) an indication for neoadjuvant treatment. Ninety-two percent prefer 5-FU-based long-course neoadjuvant chemoradiation therapy (CRT). A significant difference in practice exists between the US and non-US surgeons: poor histological differentiation as an indication for CRT (25% vs. 7.0%, p = 0.008), CRT for stage II and III rectal cancer (92% vs. 43%, p = 0.0001), MRI for all RC patients (20% vs. 42%, p = 0.03), and ERUS for all RC patients (43% vs. 21%, p = 0.01). Multidisciplinary team meetings significantly influence decisions for MRI (RR = 3.62), neoadjuvant treatment (threatened CRM, RR = 5.67, stage II + III RR = 2.98), quality of pathology report (RR = 4.85), and sphincter-saving surgery (RR = 3.81). CONCLUSIONS: There was little consensus on staging, neoadjuvant treatment, and preoperative management of rectal cancer. Regular multidisciplinary team meetings influence decisions about neoadjuvant treatment and staging methods., published_or_final_version

Published
2010

16. THE JET PRELIMINARY TRITIUM EXPERIMENT

Author

REBUT, P, ADAMS, J, ALPER, B, ALTMANN, H, ANDERSEN, A, ANDREW, P, ALIARSHAD, S, BAILEY, W, BALET, B, BARABASCHI, P, BARANOV, Y, BARKER, P, BARNSLEY, R, BARONIAN, M, BARTLETT, D, BELL, A, BENALI, G, BERTOLI, P, BERTOLINI, E, BHATNAGAR, V, BICKLEY, A, BOND, D, BONICELLI, T, BOOTH, S, BOSIA, G, BOTMAN, M, BOUCHER, D, BOUCQUEY, P, BRANDON, M, BREGER, P, BRELEN, H, BREWERTON, W, BRINKSCHULTE, H, BROWN, T, BRUSATI, M, BUDD, T, BURES, M, BURTON, P, BUSINARO, T, BUTCHER, P, BUTTGEREIT, H, CALDWELLNICHOLS, C, CAMPBELL, D, CAMPLING, D, CARD, P, CELENTANO, G, CHALLIS, C, CHANKIN, A, CHERUBINI, A, CHIRON, D, CHRISTIANSEN, J, CHUILON, P, CLAESEN, R, CLEMENT, S, CLIPSHAM, E, COAD, J, COFFEY, I, COLTON, A, COMISKEY, M, CONROY, S, COOKE, M, COOPER, S, CORDEY, J, CORE, W, CORRIGAN, G, CORTI, S, COSTLEY, A, COTTRELL, G, COX, M, CRAWLEY, P, DACOSTA, O, DAVIES, N, DAVIES, S, DEBLANK, H, DEESCH, H, DEKOCK, L, DEKSNIS, E, DELIYANAKUS, N, DENNEHINNOV, G, DESCHAMPS, G, DICKSON, W, DIETZ, K, DINES, A, DMITRENKO, S, DMITRIEVA, M, DOBBING, J, DOLGETTA, N, DORLING, S, DOYLE, P, DUCHS, D, DUQUENOY, H, EDWARDS, A, EHRENBERG, J, EKEDAHL, A, ELEVANT, T, ERENTS, S, ERIKSSON, L, FAJEMIROKUN, H, FALTER, H, FREILING, J, FROGER, C, FROISSARD, P, FULLARD, K, GADEBERG, M, GALETSAS, A, GALBIATI, L, GAMBIER, D, GARRIBBA, M, GAZE, P, GIANNELLA, R, GIBSON, A, GILL, R, GIRARD, A, GONDHALEKAR, A, GOODALL, D, GORMEZANO, C, GOTTARDI, N, GOWERS, C, GREEN, B, HAANGE, R, HAIGH, A, HANCOCK, C, HARBOUR, P, HAWKES, N, HAYNES, P, HEMMERICH, J, HENDER, T, HOEKZEMA, J, HORTON, L, HOW, J, HOWARTH, P, HUART, M, HUGHES, T, HUGUET, M, HURD, F, IDA, K, INGRAM, B, IRVING, M, JACQUINOT, J, JAECKEL, H, JAEGER, J, JANESCHITZ, G, JANKOWICZ, Z, JARVIS, O, JENSEN, F, JONES, E, JONES, L, JONES, T, JUNGER, J, JUNIQUE, F, KAYE, A, KEEN, B, KEILHACKER, M, KERNER, W, KIDD, N, KONIG, R, KONSTANTELLOS, A, KUPSCHUS, P, LASSER, R, LAST, J, LAUNDY, B, LAUROTARONI, L, LAWSON, K, LENNHOLM, M, LINGERTAT, J, LITUNOVSKI, R, LOARTE, A, LOBEL, R, LOMAS, P, LOUGHLIN, M, LOWRY, C, MAAS, A, MACKLIN, B, MAGGI, C, MAGYAR, G, MARCHESE, V, MARCUS, F, MART, J, MARTIN, D, MARTIN, E, MARTINSOLIS, R, MASSMANN, P, MATTHEWS, G, MCBRYAN, H, MCCRACKEN, G, MERIGUET, P, MIELE, P, MILLS, S, MILLWARD, P, MINARDI, E, MOHANTI, R, MONDINO, P, MONTVAI, A, MORGAN, P, MORSI, H, MURPHY, G, NAVE, F, NEUDATCHIN, S, NEWBERT, G, NEWMAN, M, NIELSEN, P, NOLL, P, OBERT, W, OBRIEN, D, OROURKE, J, OSTROM, R, OTTAVIANI, M, PAPASTERGIOU, S, PASINI, D, PATEL, B, PEACOCK, A, PEACOCK, N, PEARCE, R, PEARSON, D, PEPEDESILVA, R, PERINIC, G, PERRY, C, PICK, M, PLANCOULAINE, J, POFFE, J, POHLCHEN, R, PORCELLI, F, PORTE, L, PRENTICE, R, PUPPIN, S, PUTVINSKII, S, RADFORD, G, RAIMONDI, T, RAMOSDEANDRADE, M, RAPISARDA, M, REICHLE, R, RICHARDS, S, RIGHI, E, RIMINI, F, ROLFE, A, ROSS, R, ROSSI, L, RUSS, R, SACK, H, SADLER, G, SAIBENE, G, SALANAVE, J, SANAZZARO, G, SANTAGIUSTINA, A, SARTORI, R, SBORCHIA, C, SCHILD, P, SCHMID, M, SCHMIDT, G, SCHROEPF, H, SCHUNKE, B, SCOTT, S, SIBLEY, A, SIMONINI, R, SIPS, A, SMEULDERS, P, SMITH, R, STAMP, M, STANGEBY, P, START, D, STEED, C, STORK, D, STOTT, P, STUBBERFIELD, P, SUMMERS, D, SUMMERS, H, SVENSSON, L, TAGLE, J, TANGA, A, TARONI, A, TERELLA, C, TESINI, A, THOMAS, P, THOMPSON, E, THOMSEN, K, TREVALION, P, TUBBING, B, TIBONE, F, VANDERBEKEN, H, VLASES, G, VONHELLERMANN, M, WADE, T, WALKER, C, WARD, D, WATKINS, M, WATSON, M, WEBER, S, WESSON, J, WIJNANDS, T, WILKS, J, WILSON, D, WINKEL, T, WOLF, R, WONG, D, WOODWARD, C, WYKES, M, YOUNG, I, ZANNELLI, L, ZOLFAGHARI, A, ZULLO, G, and ZWINGMANN, W

Subjects
inorganic chemicals, Jet (fluid), Tokamak, Materials science, Lawson criterion, Joint European Torus, Plasma, Fusion power, Condensed Matter Physics, law.invention, Nuclear physics, Nuclear Energy and Engineering, Deuterium, law, cardiovascular system, Tritium
Abstract

The first tokamak discharges with deuterium-tritium mixtures have been carried out in the Joint European Torus (JET). The main objectives were to produce more than IMW of fusion power in a controlled way, to determine tritium retention in torus systems and to establish effective means of tritium removal. The experiments were undertaken within limits imposed by restrictions on vessel activation and tritium usage. Deuterium plasmas were heated by high power deuterium neutral beams from fourteen sources and fuelled by two neural beam sources injecting tritium. In the best (D-T discharge), the tritium concentration was about 11% at peak performance, when total neutron emission rate was 6.0*1017 s-1, with 1.7 MW of fusion power. The fusion amplification factor QDT was 0.15. With optimum tritium concentration, this pulse would have produced a fusion power approximately=5 MW and nominal QDT=0.46. The same extrapolation for the best pure deuterium discharge gives about 11 MW and a nominal QDT=1.14. Techniques for introducing, tracking, monitoring and recovering tritium were highly effective.

Published
2016

17. High speed wireless IR-LANs using spatial addressing

Author

Street, A, Samaras, K, OBrien, D, Edwards, D, and IEEE

Abstract

Currently, there is considerable interest in infrared as an alternative medium to radio for indoor wireless communications, particularly for computer networking applications. This paper describes a novel IR-LAN link topology that employs an optical spatial-angular mapping technique which minimizes link losses and facilitates high link rates, whilst maintaining a useful coverage area. Blocking probability effects and overall system performance are examined in terms of aggregate transmission rates.

Published
2016

18. The ACOS CO2 retrieval algorithm. Part II: Global XCO2 data characterization

Author

Crisp, D., Fisher, B. M., ODell, C., Frankenberg, C., Basilio, R., Bosch, H., Brown, L. R., Castano, R., Connor, B., Deutscher, N. M., Eldering, A., Griffith, D., Gunson, M., Mandrake, L., McDuffie, J., Messerschmidt, J., Miller, C. E., Natraj, V., Notholt, J., OBrien, D. M., Oyafuso, F., Polonsky, I., Robinson, J., Salawitch, R., Sherlock, V., Smyth, M., Taylor, T. E., Thompson, D. R., Wennberg, P. O., Wunch, D., Yung, Y. L., Kuze, Akihiko, Morino, Isamu, and Suto, Hiroshi

Abstract

資料番号: PA1110063000

Published
2012

19. International preoperative rectal cancer management: staging, neoadjuvant treatment, and impact of multidisciplinary teams

Author

Augestad, K, Lindsetmo, R, Stulberg, J, Reynolds, H, Senagore, A, Champagne, B, Heriot, A, Leblanc, F, Delaney, C, Ambrosetti, P, Andujar, J, Baixuli, J, Balen, E, Baxter, N, Beck, D, Bemelman, W, Bergamaschi, R, Billingham, R, Birch, D, Bonardi, R, Bonardi, M, Bonjer, J, Braga, M, Buch, H, Buechler, M, Burnstein, M, Campbell, K, Caushaj, P, Celebrezze, J, Chang, G, Cheong, D, Cohen, J, Colak, T, Dhoore, A, Douglas, P, Dozois, E, Efron, J, Ellis, N, Enker, W, Fanelli, R, Fazio, V, Fleshman, J, Franklin, M, Fry, R, Garcia-Aguilar, J, Garcia-Granero, E, Habr-Gama, A, Hahnloser, D, Harris, G, Hasegawa, H, Holm, T, Horgan, P, Hyman, N, Irwin, T, Joh, Y, Jongen, J, Kaiser, A, Kang, S, Kariv, Y, Kennedy, R, Kessler, H, Khan, M, Kim, S, Krokowicz, P, Kwok, S, Lacy, A, Larson, D, Law, W, Lee, E, Lippert, H, Ludwig, K, Lynch, A, Macrae, H, Madbouly, K, Maeda, K, Marderstein, E, Marino, M, Marks, J, Maurer, C, Mcleod, R, Monson, J, Mortensen, N, Neary, P, Newstead, G, Obrien, D, Orangio, G, Orkin, B, Page, M, Pahlman, L, Panis, Y, Panton, N, Pennickx, F, Phang, T, Pinedo Mancilla, G, Post, S, Rafferty, J, Rajput, A, Reis Neto dos, J, Rivadeneira, D, Roselli, J, Rosen, H, Rossi, G, Rouanet, P, Rullier, E, Schiedeck, T, Schiessel, R, Schlachta, C, Schwenk, W, Seow-Choen, F, Sim, R, Sing, W, Stamos, M, Sternberg, J, Tuckson, W, Ugolini, G, Vaccaro, C, Vargas, D, Vignali, A, Vonen, B, Weiss, E, Wexner, S, Whiteford, M, Wibe, A, Williams, N, Woods, R, Yamamoto, T, Young-Fadok, T, Augestad K. M., Lindsetmo R. -O., Stulberg J., Reynolds H., Senagore A., Champagne B., Heriot A. G., Leblanc F., Delaney C. P., Ambrosetti P., Andujar J., Baixuli J., Balen E., Baxter N., Beck D., Bemelman W., Bergamaschi R., Billingham R., Birch D., Bonardi R., Bonardi M., Bonjer J., Braga M., Buch H., Buechler M., Burnstein M., Campbell K., Caushaj P., Celebrezze J., Chang G., Cheong D., Cohen J., Colak T., Dhoore A., Douglas P., Dozois E., Efron J., Ellis N., Enker W., Fanelli R. D., Fazio V., Fleshman J., Franklin M., Fry R., Garcia-Aguilar J., Garcia-Granero E., Habr-Gama A., Hahnloser D., Harris G., Hasegawa H., Holm T., Horgan P., Hyman N., Irwin T., Joh Y. G., Jongen J., Kaiser A., Kang S. B., Kariv Y., Kennedy R., Kessler H., Khan M., Kim S. H., Krokowicz P., Kwok S., Lacy A., Larson D., Law W. L., Lee E., Lippert H., Ludwig K., Lynch A. C., MacRae H., Madbouly K., Maeda K., Marderstein E., Marino M., Marks J., Maurer C., McLeod R., Monson J., Mortensen N., Neary P., Newstead G., OBrien D., Orangio G., Orkin B., Page M., Pahlman L., Panis Y., Panton N., Pennickx F., Phang T., Pinedo Mancilla G., Post S., Rafferty J., Rajput A., Reis Neto dos J. A., Rivadeneira D., Roselli J., Rosen H., Rossi G., Rouanet P., Rullier E., Schiedeck T., Schiessel R., Schlachta C., Schwenk W., Seow-Choen F., Sim R., Sing W. K., Stamos M., Sternberg J., Tuckson W., Ugolini G., Vaccaro C., Vargas D., Vignali A., Vonen B., Weiss E., Wexner S., Whiteford M., Wibe A., Williams N., Woods R., Yamamoto T., Young-Fadok T., Augestad, K, Lindsetmo, R, Stulberg, J, Reynolds, H, Senagore, A, Champagne, B, Heriot, A, Leblanc, F, Delaney, C, Ambrosetti, P, Andujar, J, Baixuli, J, Balen, E, Baxter, N, Beck, D, Bemelman, W, Bergamaschi, R, Billingham, R, Birch, D, Bonardi, R, Bonardi, M, Bonjer, J, Braga, M, Buch, H, Buechler, M, Burnstein, M, Campbell, K, Caushaj, P, Celebrezze, J, Chang, G, Cheong, D, Cohen, J, Colak, T, Dhoore, A, Douglas, P, Dozois, E, Efron, J, Ellis, N, Enker, W, Fanelli, R, Fazio, V, Fleshman, J, Franklin, M, Fry, R, Garcia-Aguilar, J, Garcia-Granero, E, Habr-Gama, A, Hahnloser, D, Harris, G, Hasegawa, H, Holm, T, Horgan, P, Hyman, N, Irwin, T, Joh, Y, Jongen, J, Kaiser, A, Kang, S, Kariv, Y, Kennedy, R, Kessler, H, Khan, M, Kim, S, Krokowicz, P, Kwok, S, Lacy, A, Larson, D, Law, W, Lee, E, Lippert, H, Ludwig, K, Lynch, A, Macrae, H, Madbouly, K, Maeda, K, Marderstein, E, Marino, M, Marks, J, Maurer, C, Mcleod, R, Monson, J, Mortensen, N, Neary, P, Newstead, G, Obrien, D, Orangio, G, Orkin, B, Page, M, Pahlman, L, Panis, Y, Panton, N, Pennickx, F, Phang, T, Pinedo Mancilla, G, Post, S, Rafferty, J, Rajput, A, Reis Neto dos, J, Rivadeneira, D, Roselli, J, Rosen, H, Rossi, G, Rouanet, P, Rullier, E, Schiedeck, T, Schiessel, R, Schlachta, C, Schwenk, W, Seow-Choen, F, Sim, R, Sing, W, Stamos, M, Sternberg, J, Tuckson, W, Ugolini, G, Vaccaro, C, Vargas, D, Vignali, A, Vonen, B, Weiss, E, Wexner, S, Whiteford, M, Wibe, A, Williams, N, Woods, R, Yamamoto, T, Young-Fadok, T, Augestad K. M., Lindsetmo R. -O., Stulberg J., Reynolds H., Senagore A., Champagne B., Heriot A. G., Leblanc F., Delaney C. P., Ambrosetti P., Andujar J., Baixuli J., Balen E., Baxter N., Beck D., Bemelman W., Bergamaschi R., Billingham R., Birch D., Bonardi R., Bonardi M., Bonjer J., Braga M., Buch H., Buechler M., Burnstein M., Campbell K., Caushaj P., Celebrezze J., Chang G., Cheong D., Cohen J., Colak T., Dhoore A., Douglas P., Dozois E., Efron J., Ellis N., Enker W., Fanelli R. D., Fazio V., Fleshman J., Franklin M., Fry R., Garcia-Aguilar J., Garcia-Granero E., Habr-Gama A., Hahnloser D., Harris G., Hasegawa H., Holm T., Horgan P., Hyman N., Irwin T., Joh Y. G., Jongen J., Kaiser A., Kang S. B., Kariv Y., Kennedy R., Kessler H., Khan M., Kim S. H., Krokowicz P., Kwok S., Lacy A., Larson D., Law W. L., Lee E., Lippert H., Ludwig K., Lynch A. C., MacRae H., Madbouly K., Maeda K., Marderstein E., Marino M., Marks J., Maurer C., McLeod R., Monson J., Mortensen N., Neary P., Newstead G., OBrien D., Orangio G., Orkin B., Page M., Pahlman L., Panis Y., Panton N., Pennickx F., Phang T., Pinedo Mancilla G., Post S., Rafferty J., Rajput A., Reis Neto dos J. A., Rivadeneira D., Roselli J., Rosen H., Rossi G., Rouanet P., Rullier E., Schiedeck T., Schiessel R., Schlachta C., Schwenk W., Seow-Choen F., Sim R., Sing W. K., Stamos M., Sternberg J., Tuckson W., Ugolini G., Vaccaro C., Vargas D., Vignali A., Vonen B., Weiss E., Wexner S., Whiteford M., Wibe A., Williams N., Woods R., Yamamoto T., and Young-Fadok T.

Abstract

Background Little is known regarding variations in preoperative treatment and practice for rectal cancer (RC) on an international level, yet practice variation may result in differences in recurrence and survival rates. Methods One hundred seventy-three international colorectal centers were invited to participate in a survey of preoperative management of rectal cancer. Results One hundred twenty-three (71%) responded, with a majority of respondents from North America, Europe, and Asia. Ninety-three percent have more than 5 years' experience with rectal cancer surgery. Fifty-five percent use CT scan, 35% MRI, 29% ERUS, 12% digital rectal examination and 1% PET scan in all RC cases. Seventyfour percent consider threatened circumferential margin (CRM) an indication for neoadjuvant treatment. Ninety-two percent prefer 5-FU-based long-course neoadjuvant chemoradiation therapy (CRT). A significant difference in practice exists between the US and non-US surgeons: poor histological differentiation as an indication for CRT (25% vs. 7.0%, p = 0.008), CRT for stage II and III rectal cancer (92% vs. 43%, p = 0.0001), MRI for all RC patients (20% vs. 42%, p = 0.03), and ERUS for all RC patients (43% vs. 21%, p = 0.01). Multidisciplinary team meetings significantly influence decisions for MRI (RR = 3.62), neoadjuvant treatment (threatened CRM, RR = 5.67, stage II III RR = 2.98), quality of pathology report (RR = 4.85), and sphincter-saving surgery (RR = 3.81). Conclusions There was little consensus on staging, neoadjuvant treatment, and preoperative management of rectal cancer. Regular multidisciplinary team meetings influence decisions about neoadjuvant treatment and staging methods.

Published
2010

21. Investigation of relationships between linears, total and hazy areas, and petroleum production in the Williston Basin: An ERTS approach

Author

Erickson, J. M, Street, J. S, Munsell, C. J, and Obrien, D. E

Subjects
Earth Resources And Remote Sensing
Abstract

The author has identified the following significant results. ERTS-1 imagery in a variety of formats was used to locate linear, tonal, and hazy features and to relate them to areas of hydrocarbon production in the Williston Basin of North Dakota, eastern Montana, and northern South Dakota. Derivative maps of rectilinear, curvilinear, tonal, and hazy features were made using standard laboratory techniques. Mapping of rectilinears on both bands 5 and 7 over the entire region indicated the presence of a northeast-southwest and a northwest-southeast regional trend which is indicative of the bedrock fracture pattern in the basin. Curved lines generally bound areas of unique tone, maps of tonal patterns repeat many of the boundaries seen on curvilinear maps. Tones were best analyzed on spring and fall imagery in the Williston Basin. It is postulated that hazy areas are caused by atmospheric phenomena. The ability to use ERTS imagery as an exploration tool was examined where petroleum and gas are presently produced (Bottineau Field, Nesson and Antelope anticlines, Redwing Creek, and Cedar Creek anticline). It is determined that some tonal and linear features coincide with location of present production in Redwing and Cedar Creeks. In the remaining cases, targets could not be sufficiently well defined to justify this method.

Published
1975

22. Technique for recovery of voice data from heat damaged magnetic tape

Author

Melugin, J. F and Obrien, D. E., III

Subjects
Structural Mechanics
Abstract

A method for conditioning, and thus enabling retrieval of intelligence from, magnetic tapes after damage from heat has caused the tape to wrinkle and curl severely thereby reducing tape width to less than one-half its original size. The damaged tape is superposed on a first piece of splicing tape with the oxide side of the magnetic tape in contact with the adhesive side of the splicing tape and then carefully smoothed by a special tool. A second piece of splicing tape is placed on the backing side of the magnetic tape then the resulting tape stack is trimmed to the original width of the magnetic tape. After the first piece of splicing tape is carefully removed from the oxide side of the damaged magnetic tape, the resulting magnetic tape is then ready to be placed into a recorder for playback.

Published
1974

23. Heterogeneous phase reactions of Martian volatiles with putative regolith minerals

Author

Clark, B. C, Kenley, S. L, Obrien, D. L, Huss, G. R, Mack, R, and Baird, A. K

Subjects
Space Biology
Abstract

The chemical reactivity of several minerals thought to be present in Martian fines is tested with respect to gases known in the Martian atmosphere. In these experiments, liquid water is excluded from the system, environmental temperatures are maintained below 0 C, and the solar illumination spectrum is stimulated in the visible and UV using a xenon arc lamp. Reactions are detected by mass spectrometric analysis of the gas phase over solid samples. No reactions were detected for Mars nominal gas over sulfates, nitrates, chloride, nontronite clay, or magnetite. Oxidation was not observed for basaltic glass, nontronite, and magnetite. However, experiments incorporating SO2 gas an expected product of volcanism and intrusive volatile release - gave positive results. Displacement of CO2 by SO2 occurred in all four carbonates tested. These reactions are catalyzed by irradiation with the solar simulator. A calcium nitrate hydrate released NO2 in the presence of SO2. These results have implications for the cycling of atmospheric CO2, H2O, and N2 through the regolith.

Published
1979
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24. Efficient digital encoding scheme

Author

Obrien, D. E., III

Subjects
Electronic Systems
Abstract

Modified NRZ (non-return-to-zero) code immunizes record and playback systems against dc drift and bit slippage. In order to maximize bit packing density improved code called J-NRZ gives 100 percent NRZ efficiently and solves DC drift problem by adding check bits in specified format when long string is encountered. Remainder of data stream is encoded in NRZ format.

Published
1979

25. Failure analysis of composite laminates with free edges

Author

Herakovich, C. T, Nagarkar, A, and Obrien, D. A

Subjects
Structural Mechanics
Abstract

Linear elastic stress distributions obtained from a refined finite element mesh are used in conjunction with the tensor polynomial failure criterion to predict the initiation of failure in symmetric, finite-width graphite-epoxy laminates under tensile loading. Results are presented for a wide variety of laminates including: (+ and - theta)s angle-ply; cross-ply (0/90)s and (90/0)s; and quasi-isotropic (90/0/+ and - 45)s and (+ and -45/0/90)s. It is shown that the elastic stress distributions generally compare favorably with other published results, but also indicate improved satisfaction of the stress-free boundary conditions and indicate some differences in the singular behavior of selected stress components at the free edge. The tensor polynomial failure criterion is used to predict the location and mode of first failure. Examination of the individual terms of the polynomial indicates different modes of failure depending upon the laminate configuration.

Published
1979

26. Finite element stress analysis of idealized composite damage zones

Author

Obrien, D and Herakovich, C. T

Subjects
Composite Materials
Abstract

A quasi three dimensional finite element stress analysis of idealized damage zones in composite laminates is presented. The damage zones consist of a long centered groove or cutout extending one or two layers in depth from both top and bottom surfaces of a thin composite laminate. Elastic results are presented for compressive loading of four and eight layer laminates. It is shown that a boundary layer exists near the cutout edge similar to that previously shown to exist along free edges. The cutout is shown to produce significant interlaminar stresses in the interior of the laminate away from free cutout edges. The interlaminar stresses are also shown to contribute to failure which is defined using the Tsai-Wu failure criteria.

Published
1978

27. Fusion Energy-Production from a Deuterium-Tritium Plasma in the Jet Tokamak

Author

Rebut, Ph, Gibson, A., Huguet, M., Adams, Jm, Alper, B., Altmann, H., Andersen, A., Andrew, P., Angelone, M., Aliarshad, S., Baigger, P., Bailey, W., Balet, B., Barabaschi, P., Barker, P., Barnsley, R., Baronian, M., Bartlett, Dv, Baylor, L., Bell, Ac, Benali, G., Bertoldi, P., Bertolini, E., Bhatnagar, V., Bickley, Aj, Binder, D., Bindslev, H., Bonicelli, T., Booth, Sj, Bosia, G., Botman, M., Boucher, D., Boucquey, P., Breger, P., Brelen, H., Brinkschulte, H., Brooks, D., Brown, A., Brown, T., Brusati, M., Bryan, S., Brzozowski, J., Buchse, R., Budd, T., Bures, M., Businaro, T., Butcher, P., Buttgereit, H., Caldwellnichols, C., Campbell, Dj, Card, P., Celentano, G., Challis, Cd, Chankin, Av, Cherubini, A., Chiron, D., Christiansen, J., Chuilon, P., Claesen, R., Clement, S., Clipsham, E., Coad, Jp, Coffey, Ih, Colton, A., Comiskey, M., Conroy, S., Cooke, M., Cooper, D., Cooper, S., Cordey, Jg, Core, W., Corrigan, G., Corti, S., Costley, Ae, Cottrell, G., Cox, M., Cripwell, P., Dacosta, O., Davies, J., Davies, N., Deblank, H., Deesch, H., Dekock, L., Deksnis, E., Delvart, F., Dennehinnov, Gb, Deschamps, G., Dickson, Wj, Dietz, Kj, Dmitrenko, Sl, Dmitrieva, M., Dobbing, J., Doglio, A., Dolgetta, N., Dorling, Se, Doyle, Pg, Duchs, Df, Duquenoy, H., Edwards, A., Ehrenberg, J., Ekedahl, A., Elevant, T., Erents, Sk, Eriksson, Lg, Fajemirokun, H., Falter, H., Freiling, J., Freville, F., Froger, C., Froissard, P., Fullard, K., Gadeberg, M., Galetsas, A., Gallagher, T., Gambier, D., Garribba, M., Gaze, P., Giannella, R., Gill, Rd, Girard, A., Gondhalekar, A., Goodall, D., Gormezano, C., Gottardi, Na, Gowers, C., Green, Bj, Grievson, B., Haange, R., Haigh, A., Hancock, Cj, Harbour, Pj, Hartrampf, T., Hawkes, Nc, Haynes, P., Hemmerich, Jl, Hender, T., Hoekzema, J., Holland, D., Hone, M., Horton, L., How, J., Huart, M., Hughes, I., Hughes, Tp, Hugon, M., Huo, Y., Ida, K., Ingram, B., Irving, M., Jacquinot, J., Jaeckel, H., Jaeger, Jf, Janeschitz, G., Jankovicz, Z., Jarvis, On, Jensen, F., Jones, Em, Jones, Hd, Jones, Lpdf, Jones, S., Jones, Ttc, Junger, Jf, Junique, F., Kaye, A., Keen, Be, Keilhacker, M., Kelly, Gj, Kerner, W., Khudoleev, A., Konig, R., Konstantellos, A., Kovanen, M., Kramer, G., Kupschus, P., Lasser, R., Last, Jr, Laundy, B., Laurotaroni, L., Laveyry, M., Lawson, K., Lennholm, M., Lingertat, J., Litunovski, Rn, Alberto Loarte, Lobel, R., Lomas, P., Loughlin, M., Lowry, C., Lupo, J., Maas, Ac, Machuzak, J., Macklin, B., Maddison, G., Maggi, Cf, Magyar, G., Mandl, W., Marchese, V., Marcon, G., Marcus, F., Mart, J., Martin, D., Martin, E., Martinsolis, R., Massmann, P., Matthews, G., Mcbryan, H., Mccracken, G., Mckivitt, J., Meriguet, P., Miele, P., Miller, A., Mills, J., Mills, Sf, Millward, P., Milverton, P., Minardi, E., Mohanti, R., Mondino, Pl, Montgomery, D., Montvai, A., Morgan, P., Morsi, H., Muir, D., Murphy, G., Myrnas, R., Nave, F., Newbert, G., Newman, M., Nielsen, P., Noll, P., Obert, W., Obrien, D., Orchard, J., Orourke, J., Ostrom, R., Ottaviani, M., Pain, M., Paoletti, F., Papastergiou, S., Parsons, W., Pasini, D., Patel, D., Peacock, A., Peacock, N., Pearce, Rjm, Pearson, D., Peng, Jf, Desilva, Rp, Perinic, G., Perry, C., Petrov, M., Pick, Ma, Plancoulaine, J., Poffe, Jp, Pohlchen, R., Porcelli, F., Porte, L., Prentice, R., Puppin, S., Putvinskii, S., Radford, G., Raimondi, T., Deandrade, Mcr, Reichle, R., Reid, J., Richards, S., Righi, E., Rimini, F., Robinson, D., Rolfe, A., Ross, Rt, Rossi, L., Russ, R., Rutter, P., Sack, Hc, Sadler, G., Saibene, G., Salanave, Jl, Sanazzaro, G., Santagiustina, A., Sartori, R., Sborchia, C., Schild, P., Schmid, M., Schmidt, G., Schunke, B., Scott, Sm, Serio, L., Sibley, A., Simonini, R., Sips, Acc, Smeulders, P., Smith, R., Stagg, R., Stamp, M., Stangeby, P., Stankiewicz, R., Start, Df, Steed, Ca, Stork, D., Stott, Pe, Stubberfield, P., Summers, D., Summers, H., Svensson, L., Tagle, Ja, Talbot, M., Tanga, A., Taroni, A., Terella, C., Terrington, A., Tesini, A., Thomas, Pr, Thompson, E., Thomsen, K., Tibone, F., Tiscornia, A., Trevalion, P., Tubbing, B., Vanbelle, P., Vanderbeken, H., Vlases, G., Vonhellermann, M., Wade, T., Walker, C., Walton, R., Ward, D., Watkins, Ml, Watkins, N., Watson, Mj, Weber, S., Wesson, J., Wijnands, Tj, Wilks, J., Wilson, D., Winkel, T., Wolf, R., Wong, D., Woodward, C., Wu, Y., Wykes, M., Young, D., Young, Id, Zannelli, L., Zolfaghari, A., and Zwingmann, W.

Abstract

The paper describes a series of experiments in the Joint European Torus (JET), culminating in the first tokamak discharges in deuterium-tritium fuelled mixtures. The experiments were undertaken within limits imposed by restrictions on vessel activation and tritium usage. The objectives were: (i) to produce more than one megawatt of fusion power in a controlled way; (ii) to validate transport codes and provide a basis for accurately predicting the performance of deuterium-tritium plasma from measurements made in deuterium plasmas; (iii) to determine tritium retention in the torus systems and to establish the effectiveness of discharge cleaning techniques for tritium removal; (iv) to demonstrate the technology related to tritium usage; and (v) to establish safe procedures for handling tritium in compliance with the regulatory requirements. A single-null X-point magnetic configuration, diverted onto the upper carbon target, with reversed toroidal magnetic field was chosen. Deuterium plasmas were heated by high power, long duration deuterium neutral beams from fourteen sources and fuelled also by up to two neutral beam sources injecting tritium. The results from three of these high performance hot ion H-mode discharges are described: a high performance pure deuterium discharge; a deuterium-tritium discharge with a 1% mixture of tritium fed to one neutral beam source; and a deuterium-tritium discharge with 100% tritium fed to two neutral beam sources. The TRANSP code was used to check the internal consistency of the measured data and to determine the origin of the measured neutron fluxes. In the best deuterium-tritium discharge, the tritium concentration was about 11% at the time of peak performance, when the total neutron emission rate was 6.0 x 10(17) neutrons/s. The integrated total neutron yield over the high power phase, which lasted about 2 s, was 7.2 x 10(17) neutrons, with an accuracy of +/- 7%. The actual fusion amplification factor, Q(DT), was about 0.15. With an optimum tritium concentration, this pulse would have produced a fusion power of almost-equal-to 5 MW and a nominal Q(DT) almost-equal-to 0.46. The same extrapolation for the pure deuterium discharge would have given almost-equal-to 11 MW and a nominal Q(DT) = 1.14, so that the total fusion power (neutrons and alpha-particles) would have exceeded the total losses in the equivalent deuterium-tritium discharge in these transient conditions. Techniques for introducing, tracking, monitoring and recovering tritium were demonstrated to be highly effective: essentially all of the tritium introduced into the neutral beam system and, so far, about two thirds of that introduced into the torus have been recovered.

Published
1992

28. Recovery of recordings from heat damaged magnetic tapes

Author

Melugin, J. F and Obrien, D. E., III

Subjects
Electronic Systems
Abstract

Damaged tapes can now be repaired at home as long as damage does not extend to layer-to-layer adhesion within tape roll. Splice repaired section into good roll or cassette for copying. Every effort should be made to complete copying on first run, because fidelity in repaired section deteriorates with each repetition.

Published
1973

29. Apollo experience report: Lunar module instrumentation subsystem

Author

Obrien, D. E., III and Woodfill, J. R., IV

Subjects
Space Vehicles
Abstract

The design concepts and philosophies of the lunar module instrumentation subsystem are discussed along with manufacturing and systems integration. The experience gained from the program is discussed, and recommendations are made for making the subsystem more compatible and flexible in system usage. Characteristics of lunar module caution and warning circuits are presented.

Published
1972

32. High-beta regimes in JET

Author

Smeulders, P., Adams, J. M., Balet, B., Campbell, D., Cheetam, A., Corti, S., Edwards, A., Gottardi, N., Gowers, C., Hender, T. C., Huysmans, G., Jacquinot, J., Joffrin, E., Kwon, O., Lazzaro, E., Marcus, F. B., Morgan, P., Nave, F., Nielsen, P., Obrien, D., Orourke, J., Francesco Porcelli, Porte, L., Sadler, G., Sips, G., Start, D., Tanga, A., Ward, D., and Weisen, H.

Published
1990

33. AMADEUS: Advanced MAnipulator for DEep Underwater Sampling

Author

Lane, D. M., Davies, J. B. C., Robinson, G., Obrien, D. J., Pickett, M., Jones, D., Scott, E., Yang, Y., Casalino, G., Bartolini, G., Cannata, G., Ferrara, A., Angelleti, D., Mauro Coccoli, Veruggio, G., Bono, R., Virgili, P., Bruzzone, G., Canals, M., Pallas, R., Gracia, E., Smith, C., and Ieee

34. High performance Joint European Torus (JET) plasmas for deuterium-tritium operation with the MkII divertor

Author

Jones, T. T. C., Adams, J. M., Ageladarakis, P., AliArshad, S., Alper, B., Altmann, H., Andrew, P., Bainbridge, N., Bak, P., Balet, B., Baranov, Y., Barker, P., Barnsley, R., Baronian, M., Barth, K., Bartlett, D. V., Bell, A. C., Bertolini, E., Bhatnagar, V., Bickley, A. J., Bindslev, H., Blackler, K., Bond, D., Bonicelli, T., Borba, D., Brandon, M., Breger, P., Brelen, H., Brennan, P., Brewerton, W. J., Browne, M. L., Budd, T., Burt, A., Burton, P., Businaro, T., Buzio, M., CaldwellNichols, C., Campbell, D. J., Campling, D., Card, P., Celentano, G., Challis, C. D., Chankin, A. V., Cherubini, A., Chiron, D., Christiansen, J., Chuilon, P., Ciric, D., Claesen, R., Clarke, H. E., Clement, S., Coad, J. P., Cocilovo, U., Coffey, I., Conway, G., Cooper, S., Cordey, J. G., Corrigan, G., Cottrell, G., Cox, M., Crawley, P., Cusack, R., Davies, N., Davies, S. J., Davis, J. J., deBenedetti, M., deEsch, H., deHaas, J., Deksnis, E., Deliyanakis, N., diMarchi, E., Dines, A., Dmitrenko, S. L., Dobbing, J., Dolgetta, N., Dorling, S. E., Doyle, P. G., Duquenoy, H., Edwards, A. M., Edwards, A. W., Egedal, J., Ehrenberg, J., Ekedahl, A., Elevant, T., Ellis, J., Endler, M., Erents, S. K., Eriksson, L. G., Falter, H., Farthing, J. W., Fasoli, A., Fechner, B., Fichmuller, M., Fischer, B., Fishpool, G., Froger, C., Fullard, K., Gadeberg, M., Galbiati, L., Gauthier, E., Giannella, R., Gibson, A., Gill, R. D., Godden, D., Gondhalekar, A., Goniche, M., Goodall, D., Gormezano, C., Gowers, C., Graham, J., Guenther, K., Guirlet, R., Guo, H., Haigh, A., Haist, B., Hancock, C. J., Harbour, P. J., Hawkes, N. C., Hawkes, N. P., Hemmerich, J. L., Hender, T., Hoekzema, J., Horton, L., How, J., Howman, A., Huart, M., Hughes, T. P., Hurd, F., Huysmans, G., Hwang, A., Ibbott, C., Ingesson, C., Ingram, B., Irving, M., Jacquinot, J., Jaeckel, H., Jaeckel, P., Jaeger, J. F., Jarvis, I. N., Jensen, F., Johnson, M., Jones, E. M., Jones, Lpdf, Junger, J. F., Junique, F., Kaye, A., Keen, B. E., Keilhacker, M., Kerner, W., Kidd, N. G., King, Q. A., Knipe, S., Koenig, R., Krom, J. G., Kubo, H., Kupschus, P., Lamalle, P., Lasser, R., Last, J. R., LauroTaroni, L., Lawson, K., Lennholm, M., Lingertat, J., Loarte, A., Lomas, P. J., Loughlin, M., Lovegrove, T., Lowry, C., Maas, A. C., Macklin, B., Maggi, C. F., Mantsinen, M., Marchese, V., Marcus, F., Mart, J., Martin, D., Martin, T., Mathews, G., McBryan, H., McCormick, G., McCracken, G., McCullen, P. A., Meigs, A., Miele, P., Milani, F., Mills, J., Mohanti, R., Monk, R., Morgan, P., Muir, D., Murphy, G., Nave, F., Newbert, G., Nielsen, P., Noll, P., Obert, W., Obrien, D., Oord, E., Ostrom, R., Ottaviani, M., Papastergiou, S., Parail, V. V., Parkinson, R., Parsons, W., Patel, B., Paynter, A., Peacock, A., Peacock, N., Pearce, R. J. H., Perry, C., Pick, M. A., Plancoulaine, J., Pogutse, O., Porte, L., Prentice, R., Puppin, S., Radford, G., Raimondi, T., Reichle, R., Riccardo, V., Righi, E., Rimini, F., Rolfe, A., Rookes, A., Ross, R. T., Rossi, A., Rossi, L., Sadler, G., Saibene, G., Salisbury, M., Santagiustina, A., Sartori, F., Sartori, R., Saunders, R., Schild, P., Schmid, M., Schmidt, V., Schokker, B., Schunke, B., Scibile, M., Scott, S. M., Sharapov, S., Sibley, A., Simonini, R., Sips, A. C. C., Smeulders, P., Smith, O., Smith, P., Smith, R., Soldner, F., Spence, J., Springmann, E., Stamp, M., Stangeby, P., Start, D. F., Stork, D., Stott, P. E., Stubberfield, P., Summers, D., Svensson, L., Svensson, P., Tabasso, A., Tabellini, M., Tait, J., Tanga, A., Taroni, A., Terella, C., Thomas, P. R., Thomsen, K., Tubbing, B., UlHaq, Y., Vadgama, A., vanBelle, P., vanderLinden, R., Vlases, G., vonHellermann, M., Wade, T., Walton, R., Ward, D., Watkins, M. L., Watkins, N., Watson, M. J., Wesson, J., Wheatley, M., Wilson, D., Winkel, T., Woodward, C., Young, D., Young, I. D., Yu, Q., Zannelli, F., Zastrow, K. D., Zhang, W., Zornig, N., and Zwingmann, W.

Subjects
Nuclear physics, Physics, Thermonuclear fusion, Deuterium, Neutron emission, Physics::Plasma Physics, JET, Divertor, Joint European Torus, Neutron, Plasma, Magnetohydrodynamics, Condensed Matter Physics
Abstract

Planned experiments in the Joint European Torus [Plasma Physics and Controlled Fusion Research, Proceedings, 13th International Conference, Washington, D.C., 1990 (International Atomic Energy Agency, Vienna, 1991), Vol. 1, p. 27] (JET) with deuterium-tritium (D-T) plasmas require high fusion performance for alpha-particle heating studies and for investigation of isotope dependence in conditions relevant to the International Thermonuclear Experimental Reactor [Plasma Phys. Controlled Fusion 37, A19 (1995)]. In deuterium plasmas, the highest neutron rates have been obtained in the hot-ion high-confinement mode (H mode) which is ultimately limited by magnetohydrodynamic (MHD) phenomena when the pressure gradient approaches ideal ballooning and kink stability limits in the vicinity of the edge transport barrier. Results are reported confirming the MkII divertor's increased closure and pumping in this regime, progress in understanding the MHD-related termination is discussed, and the use of ion cyclotron resonance heating (ICRH) in combination with high-power neutral beams to increase the neutron yield is described. In separate experiments internal transport barriers have been established through careful programming of the current ramp and heating waveforms, and neutron emission comparable with the best hot-ion II-modes achieved. Steady-state II-mode discharges exhibiting edge localized modes (ELMs) in reactor-like configurations and conditions have been demonstrated, including cases in which relevant dimensionless parameter values are preserved, ready also for testing in D-T. (C) 1997 American institute of Physics.

35. JET - PROGRESS IN PERFORMANCE AND UNDERSTANDING

Author

Keilhacker, M., Adams, Jm, Altmann, H., Andersen, A., Andrew, P., Angelone, M., Arshad, Sa, Bailey, W., Ballantyne, P., Balet, B., Barabaschi, P., Barnsley, R., Baronian, M., Bartlett, Dv, Bell, Ac, Benfatto, I., Benali, G., Bergsaker, H., Bertoldi, P., Bertolini, E., Bhatnagar, V., Bickley, Aj, Bindslev, H., Bonicelli, T., Booth, Sj, Bosia, G., Botman, M., Boucher, D., Boucquey, P., Breger, P., Brelen, H., Brinkschulte, H., Brown, T., Brusati, M., Budd, T., Bures, M., Businaro, T., Butcher, P., Buttgereit, H., Caldwellnichols, C., Campbell, Dj, Card, P., Celentano, G., Challis, Cd, Chankin, Av, Chiron, D., Christiansen, J., Christodoulopoulos, C., Chuilon, P., Claesen, R., Clement, S., Clipsham, E., Coad, Jp, Comiskey, M., Conroy, S., Cooke, M., Cooper, S., Cordey, Jg, Core, W., Corrigan, G., Corti, S., Costley, Ae, Cottrell, G., Cox, M., Cripwell, P., Deblank, H., Deesch, H., Dekock, L., Deksnis, E., Dennehinnov, Gb, Deschamps, G., Dietz, Kj, Dmitrenko, Sl, Dobbing, J., Dolgetta, N., Dorling, Se, Doyle, Pg, Duchs, Df, Duquenoy, H., Edwards, A., Ehrenberg, J., Ekedahl, A., Elevant, T., Erents, Sk, Eriksson, Lg, Fajemirokun, H., Falter, H., Flory, D., Freiling, J., Froger, C., Froissard, P., Fullard, K., Gadeberg, M., Galetsas, A., Gambier, D., Garribba, M., Gaze, P., Giannella, R., Gibson, A., Gill, Rd, Girard, A., Gondhalekar, A., Gormezano, C., Gottardi, Na, Gowers, C., Green, Bj, Haange, R., Haas, G., Haigh, A., Gregory Hammett, Hancock, Cj, Harbour, Pj, Hawkes, Nc, Haynes, P., Hemmerich, Jl, Hender, T., Herzog, Fb, Herzog, Rf, Hoekzema, J., How, J., Huart, M., Hughes, I., Hughes, Tp, Hugon, M., Huguet, M., Hwang, A., Ingram, B., Irving, M., Jacquinot, J., Jaeckel, H., Jaeger, Jf, Janeschitz, G., Jankowicz, S., Jarvis, On, Jensen, F., Jones, Em, Jones, Lpdf, Jones, Ttc, Junger, Jf, Junique, E., Kaye, A., Keen, Be, Kelly, Gj, Kerner, W., Konig, R., Konstantellos, A., Kovanen, M., Kramer, G., Kupschus, P., Lasser, R., Last, Jr, Laundy, B., Laurotaroni, L., Lawson, K., Lennholm, M., Loarte, A., Lobel, R., Lomas, P., Loughlin, M., Lowry, C., Macklin, B., Maddison, G., Magyar, G., Mandl, W., Marchese, V., Marcus, F., Mart, J., Martin, E., Martinsolis, R., Massmann, P., Mccracken, G., Meriguet, P., Miele, P., Mills, Sf, Millward, P., Mohanti, R., Mondino, Pl, Montvai, A., Moriyama, S., Morgan, P., Morsi, H., Murphy, G., Mynarends, M., Myrnas, R., Nardone, C., Nave, F., Newbert, G., Newman, M., Nielsen, P., Noll, P., Obert, W., Obrien, D., Orourke, J., Ostrom, R., Ottaviani, M., Pain, M., Paoletti, F., Papastergiou, S., Pasini, D., Peacock, A., Peacock, N., Pearson, D., Desilva, Rp, Perinic, G., Perry, C., Pick, M., Pitts, R., Plancoulaine, J., Poffe, Jp, Porcelli, F., Porte, L., Prentice, R., Puppin, S., Putvinsko, S., Radford, G., Raimondi, T., Deandrade, Mcr, Rebut, Ph, Reichle, R., Righi, E., Rimini, F., Robinson, D., Rolfe, A., Ross, Rt, Rossi, L., Russ, R., Rutter, P., Sack, Hc, Sadler, G., Saibene, G., Salanave, Jl, Sanazzaro, G., Santagiustina, A., Sartori, R., Sborchia, C., Schild, P., Schmid, M., Schmidt, G., Schunke, B., Scott, Sm, Sibley, A., Simonini, R., Sips, Acc, Smeulders, P., Stankiewicz, R., Stamp, M., Stangeby, P., Start, Df, Steed, Ca, Stork, D., Stott, Pe, Stringer, Te, Stubberfield, P., Summers, D., Summers, H., Svensson, L., Tagle, Ja, Tanga, A., Taroni, A., Tesini, A., Thomas, Pr, Thompson, E., Thomsen, K., Todd, Jm, Trevalion, P., Tubbing, B., Tibone, F., Usselmann, E., Vanderbeken, H., Vlases, G., Vonhellermann, M., Wade, T., Walker, C., Walton, R., Ward, D., Watkins, Ml, Watson, Mj, Weber, S., Wesson, J., Wijnands, Tj, Wilks, J., Wilson, D., Winkel, T., Wolf, R., Wolle, B., Wong, D., Woodward, C., Wu, Y., Wykes, M., Young, Id, Zannelli, L., Zhu, Y., and Zwingmann, W.

36. First Results with the Modified Jet - the Jet Team

Author

Adams, J. M., Agarici, Y., Ageladarakis, P., Alper, B., Altmann, H., Andrew, P., Aliarshad, S., Bailey, W., Balet, B., Baranov, Y., Barker, P., Barnsley, R., Baronian, M., Bartlett, D. V., Bell, A. C., Benali, G., Bertolini, E., Bhatnagar, V., Bickley, A. J., Bindslev, H., Blackler, K., Bond, D., Bonicelli, T., Borras, K., Boucquey, P., Brandon, M., Breger, P., Brelen, H., Brewerton, W. J., Brown, T., Budd, T., Bures, M., Burton, P., Businaro, T., Buttgereit, H., Caldwellnichols, C., Campbell, D. J., Campling, D., Card, P., Cecil, F., Celentano, G., Challis, C. D., Chiron, D., Christiansen, J., Chuilon, P., Claesen, R., Clement, S., Coad, J. P., Colombi, S., Cooke, M., Cooper, S., Cordey, J. G., Cottrell, G., Cox, M., Crawley, P., Dacosta, O., Cusack, R., Dantona, G., Davies, N., Davies, S. J., Davis, J. J., Deesch, H., Deksnis, E., Deliyanakis, N., Dines, A., Dmitrenko, S. L., Dobbing, J., Dolgetta, N., Dorling, S. E., Doyle, P. G., Duquenoy, H., Edwards, A., Ehrenberg, J., Ekedahl, A., Elevant, T., Erents, S. K., Eriksson, L. G., Falter, H., Fasoli, A., Fechner, B., Fischer, B., Fishpool, G., Freiling, J., Froger, C., Froissard, P., Fullard, K., Gadeberg, M., Galbiati, L., Garribba, M., Gerstel, U., Giannella, R., Gibson, A., Gill, R. D., Goulding, R., Gondhalekar, A., Goodall, D., Gormezano, C., Gottardi, N. A., Gowers, C., Grisolia, C., Guo, H., Haigh, A., Hancock, C. J., Harbour, P. J., Hawkes, N. C., Hawkes, N. P., Hemmerich, J. L., Hender, T., Hoekzema, J., Horton, L., How, J., Howarth, P. J., Howman, A., Huart, M., Hutchinson, I., Hughes, T. P., Hurd, F., Ingram, B., Irving, M., Ishida, S., Jacquinot, J., Jaeckel, H., Jaeger, J. F., Jarvis, O. N., Jensen, F., Johnson, M., Jones, E. M., Jones, Lpdf, Jones, T. T. C., Junger, J. F., Junique, F., Kaye, A., Keen, B. E., Keilhacker, M., Kerner, W., Kidd, N. G., Konig, R., Kupschus, P., Lamalle, P., Lasser, R., Last, J. R., Laurotaroni, L., Laviron, C., Lawson, K., Lazzaro, E., Lennholm, M., Lingertat, J., Lomas, P., Loughlin, M., Lowry, C., Lyadina, E., Maas, A. C., Macklin, B., Maggi, C. F., Marchese, V., Marcus, F., Mart, J., Martin, D., Martin, T., Matthews, G., McBryan, H., McCormick, G., Meigs, A., Milani, S., Monk, R., Morgan, P., Murphy, G., Nave, F., Newbert, G., Nguyen, F., Nielsen, P., Noll, P., Obert, W., Obrien, D., Oord, E., Ostrom, R., Ottaviani, M., Papastergiou, S., Parail, V. V., Patel, B., Peacock, A., Peacock, N., Pearce, R. J. M., Perry, C., Pick, M. A., Plancoulaine, J., Pogutse, O., Poffe, J. P., Porcelli, F., Porte, L., Prentice, R., Puppin, S., Radford, G., Raimondi, T., Reichle, R., Richards, S., Righi, E., Rimini, F., Rolfe, A., Rookes, A., Ross, R. T., Rossi, A., Rossi, L., Russ, R., Sadler, G., Saibene, G., Salisbury, M., Sanazzaro, G., Santagiustina, A., Sartori, F., Sartori, R., Savrukhin, P., Schaffer, M., Schild, P., Schmid, M., Schunke, B., Scott, S. M., Sharapov, S., Shaw, R. L., Sibley, A., Simonini, R., Sips, A. C. C., Smeulders, P., Smith, R., Soldner, F., Stamp, M., Stangeby, P., Start, D. F., Steed, C. A., Stork, D., Stott, P. E., Stubberfield, P., Summers, D., Summers, H., Suverkropp, W., Svensson, L., Szabo, T., Tabellini, M., Tanga, A., Taroni, A., Terella, C., Tesini, A., Thomas, P. R., Thompson, E., Thomsen, K., Tubbing, B., Vanderbeken, H., Vandergoot, E., Vayakis, G., Vlases, G., Vonhellermann, M., Wade, T., Walker, C., Ward, D., Watkins, M. L., Watkins, N., Watson, M. J., Weber, S., Wesson, J., Wilson, D., Winkel, T., Wolf, R., Woodward, C., Young, I. D., Zannelli, L., Zornig, N., and Zwingmann, W.

Subjects
JET
Abstract

JET was extensively modified in the 1992/93 shutdown. The new pumped divertor and many new systems were brought into operation early in 1994. Operations have progressed to 4MA plasma current and, with substantial additional heating, H-mode confinement results confirm the expected scaling. The high power handling capability of the pumped divertor with sweeping is estimated at 20MW for 20s. H-mode plasmas have large Type I ELMs. With lower hybrid heating alone, 2MA full current drive has been achieved with good efficiency, with ICRF power, effective heating and direct electron heating have been demonstrated.

44. Electroencephalographic and electrocardiographic effects of propanidid in man.

Author

Torda TA and OBrien D

Subjects
Adolescent, Adult, Aged, Anesthesia, Intravenous, Brain drug effects, Carbon Dioxide analysis, Heart drug effects, Heart Conduction System drug effects, Heart Rate drug effects, Humans, Middle Aged, Movement, Partial Pressure, Preanesthetic Medication, Respiration drug effects, Electrocardiography, Electroencephalography, Propanidid pharmacology
Published
1971
Full Text
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