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Nobody claims to be a proponent of white feminism, but according to the critique presented in this article, many in fact are. I argue that feminism that does not take multiple axes of oppression into account is bad in three ways: (1) it strategically undermines solidarity between women; (2) it risks inconsistency by advocating justice and equality for some women but not all; and (3) it impedes the ultimate function of feminism function by employing epistemological “master’s tools” that stand in antithesis to feminist emancipatory work. In investigating ethnocentrism in feminism, I develop the idea of latent ethnocentrism, which occupies the space between meaning that is generated from reference to the self and overt racism. I identify an epistemological prong in the ethnocentrism charge against feminism, where I draw on bell hooks’ interlocking axes-model of oppression to answer why the ethnocentrism problem is important for feminism and what its underlying epistemological causes are. I draw on Uma Narayan’s destabilization of cultural dualisms to argue that they do not serve emancipatory agendas. There is a mutually constitutive relation between language that informs our understanding, on the one hand, and the political agendas that produce this language to sustain the male and the western norm as center, on the other hand. I call this circular and reciprocally reinforcing mechanism the episteme-politic. I conclude that the ethnocentrism problem is not merely an issue of (1) strategy or (2) feminist consistency but of (3) shooting oneself in the foot by uncritically accepting patriarchal concepts for feminist politics.

Background: The workplace is an ideal—and priority—setting for health promotion activities. Developing and implementing workplace health promotion interventions, including oral health promotion activities, can help create health‐supporting workplace environments. Objective: To pilot workplace oral health promotion activities among staff working in the aged care sector, report their impact and explore participants' views on the factors that contribute to participation and effectiveness. Methods: This study comprised three phases: (i) the development and face validation of the resources, (ii) a 3‐h educational session and (iii) five interview sessions with participants 4–6 weeks following the education session. The recorded interviews were transcribed verbatim and analysed thematically. Results: Eleven community‐aged care workforce were invited to five feedback sessions. Ten participants were female and ranged in age from 18 to 64. All participants gave favourable comments about the content and delivery of the training session and accompanying resources. The participants felt that the benefits of WOHP include improved staff knowledge, awareness and oral care routine, the ability to share (and put into practice) the gained knowledge and information with their dependants, a lower risk of having poor oral health that adversely affects their well‐being and work tasks, and potentially beneficial impacts on the organization's staff roster. Their attendance in the WOHP was facilitated by being paid to attend and scheduling the sessions during work time. Future WOHP suggestions include the possibility of a one‐stop dental check‐up at the workplace or staff dental care discounts from local dental practitioners and combining oral health with other health promotion activities. Conclusions: Planning and implementing WOHP was deemed acceptable and feasible in this study context and successfully achieved short‐term impacts among community‐aged care workers. Appropriate times and locations, organizational arrangements and a variety of delivery options contributed to successful programme planning and implementation. [ABSTRACT FROM AUTHOR]

DS-7423, a novel, small-molecule dual inhibitor of phosphatidylinositol-3- kinase (PI3K) and mammalian target of rapamycin (mTOR), is currently in phase I clinical trials for solid tumors. Although DS-7423 potently inhibits PI3Kα (IC50 = 15.6 nM) and mTOR

The aim of the study was to investigate the effect of prebiotic fibres on appetite-regulating hormones, subjective feeling of appetite and energy intake in subjects with type 2 diabetes. Data presented are secondary outcomes of a study investigating the effect of prebiotics on glucagon-like peptide-1 and glycaemic regulation. We conducted a randomised and placebo-controlled crossover trial to evaluate the effects of 16 g/d of inulin-type fructans or a control supplement (maltodextrin) for 6 weeks in randomised order, with a 4-week washout period in-between, on appetite in thirty-five men and women with type 2 diabetes. Data were collected at visits before and after each treatment: plasma concentration of the satiety-related peptides ghrelin and peptide YY (PYY) were assessed during a standardised mixed meal. The subjective sensation of appetite was evaluated in response to an ad libitum lunch by rating the visual analogue scale. Twenty-nine individuals (twelve women) were included in the analyses. Compared to control treatment, the prebiotics did not affect ghrelin (P =0⋅71) or the ratings of hunger (P = 0⋅62), satiety (P = 0⋅56), fullness (P = 0⋅73) or prospective food consumption (P = 0⋅98). Energy intake also did not differ between the treatments. However, the response of PYY increased significantly after the control treatment with mean (sem) 11⋅1 (4⋅3) pg/ml when compared to the prebiotics −0⋅3 (4⋅3) pg/ml (P = 0⋅013). We observed no effect of inulin-type fructans on appetite hormones, subjective feeling of appetite or energy intake in patients with type 2 diabetes.

The PI3K (phosphatidylinositol-3-kinase)/mTOR (mammalian target of rapamycin) pathway is frequently activated in endometrial cancer through various PI3K/AKT-activating genetic alterations. We examined the antitumor effect of NVP-BEZ235-a dual PI3K/mTOR inh

Bjarne K Jacobsen,1 Karen Jaceldo-Siegl,2 Synnøve F Knutsen,2 Jing Fan,2 Keiji Oda,2 Gary E Fraser2 1Department of Community Medicine, University of Tromsø, Tromsø, Norway; 2Department of Epidemiology, Biostatistics and Population Medicine, School of Public Health, Loma Linda University, Loma Linda, CA, USA Objectives: As little is known about the possible relationship between the intake of phytoestrogens and female fertility, we investigated the relationship between soy isoflavone intake and the risk of nulliparity and nulligravidity. Methods: A cross-sectional study of 11,688 North American Adventist women aged 30–50 years old with data regarding childbearing. These women were, as a group, characterized by a high proportion (54%) of vegetarians and a healthy lifestyle with a very low prevalence of smoking and alcohol use. Results: The mean isoflavone intake (17.9 mg per day) was very high compared to other Western populations. Only 6% of the women indicated no intake of isoflavones. We found, after adjustment for age, marital status, and educational level, an inverse relationship (P=0.05) between isoflavone intake and the likelihood of ever having become a mother. In women with high (≥40 mg/day) isoflavone intake (12% of this group of women), the adjusted lifetime probability of giving birth to a live child was reduced by approximately 3% (95% CI:0, 7) compared to women with low (