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1. Factors impacting antibody kinetics, including fever and vaccination intervals, in SARS-CoV-2-naïve adults receiving the first four mRNA COVID-19 vaccine doses

Author

Matsuura, Tomoka, Fukushima, Wakaba, Nakagama, Yu, Kido, Yasutoshi, Kase, Tetsuo, Kondo, Kyoko, Kaku, Natsuko, Matsumoto, Kazuhiro, Suita, Asae, Mukai, Emiko, Nitahara, Yuko, Konishi, Ayako, Kasamatsu, Ayane, Nakagama, Sachie, Nakagami-Yamaguchi, Etsuko, Ohfuji, Satoko, Kaneko, Yukihiro, Kaneko, Akira, Kakeya, Hiroshi, and Hirota, Yoshio

Published
2024
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2. Excess mortality in COVID-19-affected solid organ transplant recipients across the pandemic

Author

Unagami, Kohei, Ishida, Hideki, Omoto, Kazuya, Kasahara, Mureo, Uchida, Hajime, Sakamoto, Seisuke, Futamura, Kenta, Nishikawa, Kenta, Imamura, Ryoichi, Nakazawa, Shigeaki, Hatano, Etsuro, Ito, Takashi, Masano, Yuki, Nishihira, Morikuni, Hirata, Yuta, Sakuma, Yasunaru, Onishi, Yasuharu, Yokoyama, Naoki, Yamamoto, Shingo, Yamada, Yusuke, Ogura, Yasuhiro, Kurata, Nobuhiko, Uchida, Junji, Kabei, Kazuya, Iwamoto, Hitoshi, Ikeda, Chie, Shinoda, Kazunobu, Yoshiike, Miki, Hotta, Kiyohiko, Hidaka, Yuji, Iwami, Daiki, Ishii, Yasuo, Kamiyama, Manabu, Yoshizumi, Tomoharu, Kosai-Fujimoto, Yukiko, Kobayashi, Takaaki, Motoyama, Kentaro, Yamamoto, Megumi, Asai, Toshihiro, Tasaki, Masayuki, Kenmochi, Takashi, Ito, Taihei, Tokodai, Kazuaki, Fujio, Atsushi, Tsukamoto, Yasumasa, Watanabe, Takuya, Akamatsu, Nobuhisa, Yamashina, Sachi, Ishii, Daisuke, Kitajima, Kazuki, Yamada, Yasutoshi, Mitsuke, Akihiko, Sakaguchi, Takashi, Nakamura, Michio, Tomita, Yusuke, Nakamura, Yuki, Ishimoto, Tatsuro, Ohdan, Hideki, Tanimine, Naoki, Fujiwara, Takuzo, Yanagihara, Mitsuki, Hatakeyama, Shingo, Takai, Manabu, Nose, Kazuhiro, Kikuchi, Takashi, Mori, Yasunori, Araki, Motoo, Sekito, Takanori, Nishimura, Shingo, Tanabe, Tatsu, Igarashi, Yuto, Hidaka, Sumi, Watanabe, Masaaki, Ariyoshi, Yuichi, Hasegawa, Yasushi, Kamiyama, Masato, Yoneda, Tatsuo, Shimizu, Tomokazu, Nishikawa, Kouhei, Fukumoto, Takumi, Kuramitsu, Kaoru, Kato, Masashi, Saito, Mitsuru, Shinkai, Makoto, Usui, Hidehito, Sato, Masaaki, Eguchi, Hidetoshi, Imamura, Hiroki, Kobayashi, Shogo, Soejima, Yuji, Mita, Atsuyoshi, Kobayashi, Takashi, Nakamura, Kenji, Ohtsuka, Masayuki, Nakada, Shinichiro, Yagi, Takahito, Yasui, Kazuya, Matsuno, Naoto, Mizuno, Chiharu, Sugimoto, Mikio, Ueda, Nobufumi, Okada, Yoshinori, Hirama, Takashi, Toyooka, Shinichi, Sugimoto, Seiichiro, Matsubara, Kei, Ikegami, Toru, Furukawa, Kenei, Nitta, Hiroyuki, Katagiri, Hirokatsu, Onita, Toru, Shiraishi, Takeshi, Mizuno, Shugo, Amiya, Eisuke, Shintani, Yasushi, Kanou, Takashi, Funaki, Soichiro, Miura, Yoshifumi, Nakajima, Daisuke, Urahashi, Taizen, Matsumiya, Goro, Watanabe, Michiko, Ebisu, Yosuke, Osawa, Ryosuke, Ono, Minoru, Sogawa, Hiroshi, Gomi, Harumi, Chen-Yoshikawa, Toyofumi, Yoshida, Kazunari, Ogawa, Naoko, Yamanaga, Shigeyoshi, Shimata, Keita, Ohfuji, Satoko, Yoshikawa, Mikiko, Natori, Yoichiro, Hibi, Taizo, Yuzawa, Kenji, and Egawa, Hiroto

Published
2024
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3. Antibody responses after BNT162b2 vaccination in Japanese geriatric intermediate care facilities

Author

Suita, Asae, Ohfuji, Satoko, Kasamatsu, Ayane, Kondo, Kyoko, Nakata, Hiroyuki, Kita, Tetsuya, Deguchi, Akifumi, Fujimoto, Mikio, Iba, Kazuko, Sakamoto, Hideki, Iwasaka, Kaori, Sakamoto, Noboru, Sakamoto, Hikaru, Yodoi, Yoshiko, Kido, Yasutoshi, Nakagama, Yu, Konishi, Ayako, Mukai, Emiko, Matsumoto, Kazuhiro, Matsuura, Tomoka, Kase, Tetsuo, Kakeya, Hiroshi, Fukushima, Wakaba, and Hirota, Yoshio

Published
2023
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5. Guidelines for the diagnosis and treatment of idiopathic portal hypertension, extrahepatic portal obstruction, and Budd–Chiari syndrome in Japan.

Author

Furuichi, Yoshihiro, Kage, Masayoshi, Ohta, Masayuki, Ohfuji, Satoko, Sasaki, Hideyuki, Hidaka, Hisashi, Yoshida, Hiroshi, Kanto, Tatsuya, Kusano, Hironori, Akahoshi, Tomohiko, Obara, Katsutoshi, Hashizume, Makoto, Kuniyoshi, Yukio, Kawaguchi, Takumi, Okubo, Hironao, Ishikawa, Tsuyoshi, Hirooka, Masashi, Iwakiri, Yasuko, Nio, Masaki, and Tanaka, Atsushi

Subjects
PORTAL hypertension, HEMODYNAMICS, DIAGNOSIS, SYNDROMES, JURISDICTION
Abstract

This is the English version of the guidelines for the diagnosis and treatment of idiopathic portal hypertension, extrahepatic portal obstruction, and Budd–Chiari syndrome, which were established and revised in 2018 by the Aberrant Portal Hemodynamics Study Group under the jurisdiction of the Ministry of Health, Labor, and Welfare in Japan. These guidelines are excerpts, and the full version consists of 86 clinical questions and explanations, totaling 183 pages in Japanese. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Epidemiology of Fontan‐associated liver disease in Japan: Results from a nationwide survey in 2021.

Author

Ohfuji, Satoko, Tanaka, Atsushi, Kogiso, Tomomi, and Kanto, Tatsuya

Subjects
*STATISTICAL sampling, *RANDOM numbers, *HEPATIC fibrosis, *CARDIAC surgery, *LIVER disease diagnosis
Abstract

Aim: Although the Fontan procedure has improved the survival of patients with single‐ventricle heart disease, the long‐term consequences of the procedure have been a concern. This study aimed to explore the patients' postoperative clinical characteristics, including a diagnosis of Fontan‐associated liver disease (FALD). Methods: A nationwide Japanese epidemiological survey of post‐Fontan patients was undertaken in 2021. The survey targets were selected from all departments of pediatrics, pediatric surgery, cardiology, cardiovascular surgery, and gastroenterology using stratified random sampling by the number of beds. Each department was asked to complete a mail‐back questionnaire on the numbers of patients and their clinical characteristics. The diagnosis of FALD was made by each attending physician. Results: The estimated number of post‐Fontan patients was 7810 (95% confidence interval, 5430−10 200) in 2020, with a period prevalence of 61.9 per million. During the follow‐up of 13.8 years after the Fontan procedure, 40% of patients were diagnosed with FALD. An elevated γ‐glutamyl transpeptidase level was the most common finding leading to the FALD diagnosis (41%), and 45% of the patients also showed liver fibrosis. Compared with non‐FALD patients, FALD patients were older, had longer duration since the Fontan procedure, and had more severe cardiac or liver conditions. However, more than half of the non‐FALD patients had elevated liver enzyme levels, suggesting underestimation of the number of FALD patients. Conclusions: In 2020, approximately 40% of post‐Fontan patients underwent follow‐up with a diagnosis of FALD, although the lack of established diagnostic criteria for FALD could affect the reported prevalence of FALD. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Environmental factors, medical and family history, and comorbidities associated with primary biliary cholangitis in Japan: a multicenter case–control study

Author

Matsumoto, Kosuke, Ohfuji, Satoko, Abe, Masanori, Komori, Atsumasa, Takahashi, Atsushi, Fujii, Hideki, Kawata, Kazuhito, Noritake, Hidenao, Tadokoro, Tomoko, Honda, Akira, Asami, Maiko, Namisaki, Tadashi, Ueno, Masayuki, Sato, Ken, Kakisaka, Keisuke, Arakawa, Mie, Ito, Takanori, Tanaka, Kazunari, Matsui, Takeshi, Setsu, Toru, Takamura, Masaaki, Yasuda, Satoshi, Katsumi, Tomohiro, Itakura, Jun, Sano, Tomoya, Tamura, Yamato, Miura, Ryo, Arizumi, Toshihiko, Asaoka, Yoshinari, Uno, Kiyoko, Nishitani, Ai, Ueno, Yoshiyuki, Terai, Shuji, Takikawa, Yasuhiro, Morimoto, Youichi, Yoshiji, Hitoshi, Mochida, Satoshi, Ikegami, Tadashi, Masaki, Tsutomu, Kawada, Norifumi, Ohira, Hiromasa, and Tanaka, Atsushi

Published
2022
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9. Safety and effectiveness of SARS‐CoV‐2 vaccines for patients with intractable hepatobiliary diseases: A multicenter, questionnaire‐based, cross‐sectional study.

Author

Tanifuji, Ayaka, Ohfuji, Satoko, Matsumoto, Kosuke, Abe, Masanori, Komori, Atsumasa, Takahashi, Atsushi, Kawata, Kazuhito, Sato, Ken, Joshita, Satoru, Umemura, Takeji, Ueno, Masayuki, Nakayama, Nobuaki, Kakisaka, Keisuke, Arinaga‐Hino, Teruko, Ito, Koichi, Kanai, Sachiko, Miura, Ryo, Arizumi, Toshihiko, Asaoka, Yoshinari, and Ito, Takanori

Subjects
*CHOLANGITIS, *SARS-CoV-2, *COVID-19 vaccines, *VACCINE effectiveness, *BUDD-Chiari syndrome, *AUTOIMMUNE hepatitis
Abstract

Aim: There are few data regarding the safety and effectiveness of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines in patients with intractable hepatobiliary diseases. We conducted a multicenter, questionnaire‐based, cross‐sectional study to determine the safety and effectiveness of the SARS‐CoV‐2 vaccines in Japanese patients with intractable hepatobiliary disease. Methods: Patients aged ≥18 years with autoimmune hepatitis (AIH), primary biliary cholangitis, primary sclerosing cholangitis, Budd–Chiari syndrome, idiopathic portal hypertension, and extrahepatic portal vein obstruction at each center were consecutively invited to join the study. Participants were asked to complete a questionnaire regarding their characteristics, vaccination status, post‐vaccination adverse effects, and SARS‐CoV‐2 infection. Additionally, liver disease status, treatment regimens, and liver function test values pre‐ and post‐vaccination were collected. Results: The survey was conducted from September 2021 to May 2022, and 528 patients (220 AIH, 251 primary biliary cholangitis, 6 AIH– primary biliary cholangitis/primary sclerosing cholangitis overlap, 39 primary sclerosing cholangitis, 4 Budd–Chiari syndrome, 5 idiopathic portal hypertension, and 3 extrahepatic portal vein obstruction) participated in the study. Post‐vaccination adverse effects were comparable to those observed in the general population. Post‐vaccination liver injuries classified as grade 1 or higher were observed in 83 cases (16%), whereas grades 2 and 3 were observed in only six cases (1.1%); AIH‐like liver injury requiring treatment was not observed. Overall, 12 patients (2.3%) were infected with SARS‐CoV‐2, and only one patient was infected 6 months after the second vaccination. Conclusion: SARS‐CoV‐2 vaccines demonstrated satisfactory safety and effectiveness in Japanese patients with intractable hepatobiliary diseases. [ABSTRACT FROM AUTHOR]

Published
2024
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12. No association between inactivated influenza vaccination and influenza viral load at diagnosis among young Japanese children: An observational study of the 2013/2014 through 2017/2018 influenza seasons

Author

Mukai, Emiko, primary, Fukushima, Wakaba, additional, Morikawa, Saeko, additional, Nakata, Keiko, additional, Hiroi, Satoshi, additional, Fujioka, Masashi, additional, Matsushita, Tohru, additional, Kubota, Megumi, additional, Yagi, Yoshina, additional, Takechi, Tetsuhisa, additional, Takasaki, Yoshio, additional, Shindo, Shizuo, additional, Yamashita, Yuji, additional, Yokoyama, Takato, additional, Kiyomatsu, Yumi, additional, Matsumoto, Kazuhiro, additional, Maeda, Akiko, additional, Kondo, Kyoko, additional, Ito, Kazuya, additional, Kase, Tetsuo, additional, Ohfuji, Satoko, additional, and Hirota, Yoshio, additional

Published
2023
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19. Comparison of BNT162b2 and mRNA1273 vaccines in solid organ transplant recipients: Post‐Hoc analysis of a Japanese national prospective study.

Author

Yoshikawa, Mikiko, Natori, Yoichiro, Oki, Rikako, Unagami, Kohei, Ohfuji, Satoko, Imamura, Ryoichi, Ishida, Hideki, Takahara, Shiro, Hirota, Yoshio, and Egawa, Hiroto

Subjects
SARS-CoV-2, COVID-19, COVID-19 vaccines, TRANSPLANTATION of organs, tissues, etc., VACCINE immunogenicity
Abstract

The coronavirus disease‐19 (COVID‐19) vaccine efficacy and immunogenicity in the immunocompetent population are well established. However, in solid organ transplant (SOT) recipients, because of their use of immunosuppressive medication, the immunogenicity of these severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines remains suboptimal. Both BNT162b2 and mRNA1273 have been used for some time, but their immunogenicity has not been directly compared in this immunocompromised patient group. We performed a post‐hoc analysis of a previous prospective cohort study. The inclusion criteria were adult SOT recipients with active grafts at least 1 month after SOT. After giving consent, participants chose to receive either BNT162b2 or mRNA1273 vaccine. Anti‐spike‐protein‐S antibody against SARS‐CoV‐2 was measured. Propensity scores were calculated via logistic regression to transform the probability of having received either BNT162b2 or mRNA1273 vaccine, and a model was developed. We enrolled 623 SOT recipients. In the propensity score‐matched analysis, 100 recipients were selected for BNT162b2 and 100 for mRNA1273. SARS‐CoV‐2 anti‐spike protein antibody positivity with BNT162b2 versus mRNA1273 at 3 weeks after the first dose, 1 month after the second dose, 3 months after the second dose, and 6 months after the second dose were 10% versus 19% (P =.07), 51% versus 58% (P =.30), 74% versus 88% (P =.01), and 78% versus 87% (P =.13), respectively. We conducted a propensity score‐matched comparison of BNT162b2 and mRNA1273 vaccines as the primary series of COVID‐19 vaccines in SOT recipients. We found significantly better immunogenicity with the mRNA1273 vaccine than with BNT162b2. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Pretreatment serum monocyte chemoattractant protein‐1 as a predictor of long‐term outcome by ustekinumab in patients with Crohn's disease

Author

Okuda, Hiroaki, primary, Hosomi, Shuhei, additional, Itani, Shigehiro, additional, Kurimoto, Noriyuki, additional, Kobayashi, Yumie, additional, Nakata, Rieko, additional, Nishida, Yu, additional, Ominami, Masaki, additional, Nadatani, Yuji, additional, Fukunaga, Shusei, additional, Otani, Koji, additional, Kamata, Noriko, additional, Tanaka, Fumio, additional, Nagami, Yasuaki, additional, Taira, Koichi, additional, Ohfuji, Satoko, additional, and Fujiwara, Yasuhiro, additional

Published
2023
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22. Incidence and risk factors for norovirus‐related diarrhea in Japanese geriatric intermediate care facilities: A prospective cohort study

Author

Suita, Asae, primary, Ohfuji, Satoko, additional, Fukushima, Wakaba, additional, Ito, Kazuya, additional, Kase, Tetsuo, additional, Kondo, Kyoko, additional, Ishibashi, Motoki, additional, Kumashiro, Hiroko, additional, Kawai, Shuji, additional, Deguchi, Akifumi, additional, Nakata, Hiroyuki, additional, Iba, Kazuko, additional, Kita, Tetsuya, additional, Kinugawa, Kazuhiko, additional, Hamada, Kazutaka, additional, Fujimoto, Mikio, additional, Furukawa, Yoshio, additional, Sowa, Etsuji, additional, Nakazawa, Hideo, additional, and Hirota, Yoshio, additional

Published
2023
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23. Antibody Responses after Bnt162b2 Vaccination in Japanese Geriatric Intermediate Care Facilities

Author

Suita, Asae, primary, Ohfuji, Satoko, additional, Kasamatsu, Ayane, additional, Kondo, Kyoko, additional, Nakata, Hiroyuki, additional, Kita, Tetsuya, additional, Deguchi, Akifumi, additional, Fujimoto, Mikio, additional, Iba, Kazuko, additional, Sakamoto, Hideki, additional, Iwasaka, Kaori, additional, Sakamoto, Noboru, additional, Sakamoto, Hikaru, additional, Yodoi, Yoshiko, additional, Kido, Yasutoshi, additional, Nakagama, Yu, additional, Konishi, Ayako, additional, Mukai, Emiko, additional, Matsumoto, Kazuhiro, additional, Matsuura, Tomoka, additional, Kase, Tetsuo, additional, Kakeya, Hiroshi, additional, Fukushima, Wakaba, additional, and Hirota, Yoshio, additional

Published
2023
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26. Incidence of Mumps Deafness in Japan, 2005–2017: Analysis of Japanese Insurance Claims Database

Author

Takagi, Akira, Ohfuji, Satoko, Nakano, Takashi, Kumihashi, Hideaki, Kano, Munehide, and Tanaka, Toshihiro

Subjects
Medicine (General), Pediatrics, medicine.medical_specialty, Epidemiology, 030209 endocrinology & metabolism, Mumps virus, medicine.disease_cause, congenital deafness, Insurance claims, mumps vaccine, 03 medical and health sciences, R5-920, 0302 clinical medicine, Incidence data, otorhinolaryngologic diseases, Health insurance, medicine, Clinical Epidemiology, 030212 general & internal medicine, mumps deafness, unilateral neurosensory deafness, Disease burden, business.industry, Incidence (epidemiology), General Medicine, Mumps vaccine, Original Article, Observational study, business
Abstract

Background: Mumps deafness causes serious problems, and incidence data are needed to identify its disease burden. However, such data are limited, and the reported incidence is highly variable. Nationwide studies in Japan with a large age range are lacking. Methods: This was a retrospective observational investigation of the 2005–2017 mumps burden using employment-based health insurance claims data. Data were analyzed for 5,190,326 people aged 0–64 years to estimate the incidence of mumps deafness. Results: Of 68,112 patients with mumps (36,423 males; 31,689 females), 102 (48 males; 54 females) developed mumps deafness—an incidence of 15.0 per 10,000 patients (1 in 668 patients). Fifty-four (52.9%) patients had mumps deafness in childhood (0–15 years), and 48 (47.1%) had mumps deafness in adolescence and adulthood (16–64 years); most cases occurred in childhood, the peak period for mumps onset. The incidence of mumps deafness per 10,000 patients was 73.6 in adolescence and adulthood, 8.4 times higher than the incidence of 8.8 in childhood (P < 0.001). In childhood, the incidence of mumps deafness was 7.2 times higher among 6–15-year-olds (13.8; 95% CI, 10.2–18.2) than among 0–5-year-olds (1.9; 95% CI, 0.6–4.5), and this difference was statistically significant (P < 0.001). No sex difference was observed. Conclusions: The incidence of mumps deafness per 10,000 patients aged 0–64 years was 15.0 (1 in 668 patients). A secondary risk of deafness following mumps virus infection was identified not only for children, but also for adolescents and adults.

Published
2022
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29. Influence of a biliary stent in patients with advanced pancreatic cancer treated with modified FOLFIRINOX

Author

Yoshikawa-Kimura, Akie, primary, Taira, Koichi, additional, Maruyama, Hirotsugu, additional, Ishikawa-Kakiya, Yuki, additional, Yamamura, Masafumi, additional, Tanoue, Kojiro, additional, Hagihara, Atsushi, additional, Uchida-Kobayashi, Sawako, additional, Enomoto, Masaru, additional, Kimura, Kenjiro, additional, Tanaka, Shogo, additional, Amano, Ryosuke, additional, Takemura, Shigekazu, additional, Ohfuji, Satoko, additional, Tanaka, Fumio, additional, Nagami, Yasuaki, additional, and Fujiwara, Yasuhiro, additional

Published
2022
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31. Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against community-acquired pneumonia in older individuals after the introduction of childhood 13-valent pneumococcal conjugate vaccine: A multicenter hospital-based case-control study in Japan

Author

Nakashima, Kei, primary, Suzuki, Kanzo, additional, Aoshima, Masahiro, additional, Murabata, Mayumi, additional, Kondo, Kyoko, additional, Ohfuji, Satoko, additional, Fukushima, Wakaba, additional, Maeda, Akiko, additional, and Hirota, Yoshio, additional

Published
2022
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33. Kinetics of anti-SARS-CoV-2 antibody titer in healthy adults up to 6 months after BNT162b2 vaccination measured by two immunoassays: A prospective cohort study in Japan

Author

Matsuura, Tomoka, primary, Fukushima, Wakaba, additional, Nakagama, Yu, additional, Kido, Yasutoshi, additional, Kase, Tetsuo, additional, Kondo, Kyoko, additional, Kaku, Natsuko, additional, Matsumoto, Kazuhiro, additional, Suita, Asae, additional, Komiya, Eriko, additional, Mukai, Emiko, additional, Nitahara, Yuko, additional, Konishi, Ayako, additional, Kasamatsu, Ayane, additional, Nakagami-Yamaguchi, Etsuko, additional, Ohfuji, Satoko, additional, Kaneko, Yukihiro, additional, Kaneko, Akira, additional, Kakeya, Hiroshi, additional, and Hirota, Yoshio, additional

Published
2022
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37. Effect of the Coronavirus Disease 2019 Lockdown on Lifestyle Factors in Japanese Patients with Inflammatory Bowel Disease

Author

Nishida, Yu, primary, Hosomi, Shuhei, additional, Fujimoto, Koji, additional, Nakata, Rieko, additional, Itani, Shigehiro, additional, Ohminami, Masaki, additional, Nadatani, Yuji, additional, Fukunaga, Shusei, additional, Otani, Koji, additional, Tanaka, Fumio, additional, Nagami, Yasuaki, additional, Taira, Koichi, additional, Kamata, Noriko, additional, Ohfuji, Satoko, additional, and Fujiwara, Yasuhiro, additional

Published
2022
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40. Osteoarthritis hip joints in Japan: involvement of acetabular dysplasia

Author

Jingushi, Seiya, Itoman, Moritoshi, Miyanishi, Keita, Ohfuji, Satoko, Hirota, Yoshio, Sofue, Muroto, Iga, Toshiro, Matsumoto, Tadami, Sugimori, Tanzo, Hamada, Yoshiki, Shindo, Hiroyuki, Okano, Kunihiko, Takatori, Yoshio, Yamada, Harumoto, Ando, Kenichi, Yasunaga, Yuji, Hamaki, Takanari, Ito, Hiroshi, Hirayama, Teruhisa, Mori, Satoshi, Owan, Ichiro, Nakasone, Satoshi, Fujii, Genji, Ohashi, Hirotsugu, Matsuura, Masanori, Iwamoto, Yukihide, Mawatari, Taro, Takahira, Naonobu, Sugiyama, Hajime, Karita, Tatsuro, and Iwata, Ken

Published
2011
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44. Smoking and drinking habits relating to development of ulcerative colitis in Japanese: A multicenter case–control study.

Author

Kondo, Kyoko, Ono, Yu, Ohfuji, Satoko, Watanabe, Kenji, Yamagami, Hirokazu, Watanabe, Mamoru, Nishiwaki, Yuji, Fukushima, Wakaba, Hirota, Yoshio, and Suzuki, Yasuo

Subjects
ULCERATIVE colitis, SMOKING cessation, CASE-control method, SMOKING, JAPANESE people
Abstract

Background and Aim: The number of patients with ulcerative colitis (UC) has been increasing in Japan. To elucidate the risk factors for developing UC in Japan, a hospital‐based case–control study was conducted. This study examined the association between smoking/drinking habits and UC onset in detail. Methods: Cases comprised 132 Japanese patients who had been newly diagnosed with UC between 2008 and 2014 at 38 collaborating hospitals in Japan, and controls comprised 167 patients without UC. Detailed data on smoking and drinking habits were collected using a self‐administered questionnaire. Results: Ex‐smokers showed an increasing odds ratio (OR) for UC development compared with never smokers (OR 2.42, 95% confidence interval 1.24–4.72). The ORs of ex‐smokers were particularly high among subjects aged less than 40 years, subjects who had smoked more than 10 pack‐years, and subjects who were within 13 years of quitting smoking. Regarding drinking habits, ex‐drinkers also showed a more than twofold higher OR for UC compared to never drinkers. Ex‐drinkers 40 years or older, ex‐drinkers who had consumed more than 364 drink‐years, and subjects who were less than 6 years after quitting drinking showed increased ORs for UC. Conclusion: These findings suggest the need for careful attention for UC onset among heavy smokers who quit smoking before 40 years of age and heavy drinkers who quit drinking at ≥40 years of age. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Multiinstitutional epidemiological study regarding osteoarthritis of the hip in Japan

Author

Jingushi, Seiya, Ohfuji, Satoko, Sofue, Muroto, Hirota, Yoshio, Itoman, Moritoshi, Matsumoto, Tadami, Hamada, Yoshiki, Shindo, Hiroyuki, Takatori, Yoshio, Yamada, Harumoto, Yasunaga, Yuji, Ito, Hiroshi, Mori, Satoshi, Owan, Ichiro, Fujii, Genji, Ohashi, Hirotsugu, Iwamoto, Yukihide, Miyanishi, Keita, Iga, Toshiro, Takahira, Naonobu, Sugimori, Tanzo, Sugiyama, Hajime, Okano, Kunihiko, Karita, Tatsuro, Ando, Kenichi, Hamaki, Takanari, Hirayama, Teruhisa, Iwata, Ken, Nakasone, Satoshi, Matsuura, Masanori, and Mawatari, Taro

Published
2010
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46. Impact of the Lockdown Due to the COVID-19 Pandemic on Patients With Inflammatory Bowel Disease

Author

Nishida, Yu, primary, Hosomi, Shuhei, additional, Fujimoto, Koji, additional, Nakata, Rieko, additional, Sugita, Naoko, additional, Itani, Shigehiro, additional, Nadatani, Yuji, additional, Fukunaga, Shusei, additional, Otani, Koji, additional, Tanaka, Fumio, additional, Nagami, Yasuaki, additional, Taira, Koichi, additional, Kamata, Noriko, additional, Watanabe, Toshio, additional, Ohfuji, Satoko, additional, and Fujiwara, Yasuhiro, additional

Published
2021
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47. Influence of Prior Influenza Vaccination on Current Influenza Vaccine Effectiveness in Children Aged 1 to 5 Years

Author

Matsumoto, Kazuhiro, primary, Fukushima, Wakaba, additional, Morikawa, Saeko, additional, Fujioka, Masashi, additional, Matsushita, Tohru, additional, Kubota, Megumi, additional, Yagi, Yoshina, additional, Takasaki, Yoshio, additional, Shindo, Shizuo, additional, Yamashita, Yuji, additional, Yokoyama, Takato, additional, Kiyomatsu, Yumi, additional, Hiroi, Satoshi, additional, Nakata, Keiko, additional, Maeda, Akiko, additional, Kondo, Kyoko, additional, Ito, Kazuya, additional, Kase, Tetsuo, additional, Ohfuji, Satoko, additional, and Hirota, Yoshio, additional

Published
2021
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48. Environmental factors, medical and family history, and comorbidities associated with primary biliary cholangitis in Japan: a multicenter case–control study

Author

Matsumoto, Kosuke, primary, Ohfuji, Satoko, additional, Abe, Masanori, additional, Komori, Atsumasa, additional, Takahashi, Atsushi, additional, Fujii, Hideki, additional, Kawata, Kazuhito, additional, Noritake, Hidenao, additional, Tadokoro, Tomoko, additional, Honda, Akira, additional, Asami, Maiko, additional, Namisaki, Tadashi, additional, Ueno, Masayuki, additional, Sato, Ken, additional, Kakisaka, Keisuke, additional, Arakawa, Mie, additional, Ito, Takanori, additional, Tanaka, Kazunari, additional, Matsui, Takeshi, additional, Setsu, Toru, additional, Takamura, Masaaki, additional, Yasuda, Satoshi, additional, Katsumi, Tomohiro, additional, Itakura, Jun, additional, Sano, Tomoya, additional, Tamura, Yamato, additional, Miura, Ryo, additional, Arizumi, Toshihiko, additional, Asaoka, Yoshinari, additional, Uno, Kiyoko, additional, Nishitani, Ai, additional, Ueno, Yoshiyuki, additional, Terai, Shuji, additional, Takikawa, Yasuhiro, additional, Morimoto, Youichi, additional, Yoshiji, Hitoshi, additional, Mochida, Satoshi, additional, Ikegami, Tadashi, additional, Masaki, Tsutomu, additional, Kawada, Norifumi, additional, Ohira, Hiromasa, additional, and Tanaka, Atsushi, additional

Published
2021
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