157 results on '"Ohkubo, Mitsuru"'
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2. Data from MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel
3. Supplementary Table 1 from MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel
4. Supplementary Figure 2 from MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel
5. Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema
6. Solid-phase synthesis of aryl, heteroaryl, and sterically hindered alkyl amines using the Curtius rearrangement
7. In Vitro Pharmacological Characterization of Novel Isoxazolopyridone Derivatives as Allosteric Metabotropic Glutamate Receptor 7 Antagonists
8. Difference in Discharge Threshold Voltage Between Electron Beam and Ultraviolet Environment
9. Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling
10. Synthesis and characterization of coronanes: multicyclopropane-fused macrocyclic arrays
11. Design, synthesis, and structure–activity relationships of potent GPIIb/IIIa antagonists: discovery of FK419
12. Dess-Martin periodinane oxidation of alcohols in the presence of stabilized phosphorus ylides: a convenient method for the homologaion of alcohols via unstable aldehydes
13. Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor
14. Synthesis and biological activities of topoisomerase I inhibitors, 6- N-amino analogues of NB-506
15. Synthesis and biological activities of NB-506 analogues: Effects of the positions of two hydroxyl groups at the indole rings
16. Solid phase synthesis of aryl and heteroaryl amines using the Curtius rearrangement
17. Development of a New Indolocarbazole Anticancer Agent(NB-506)
18. Discovery of 3‑Ethyl-4-(3-isopropyl-4-(4-(1-methyl‑1H‑pyrazol-4-yl)‑1H‑imidazol-1-yl)‑1H‑pyrazolo[3,4‑b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor.
19. Orally available pyridinylpyrimidine derivatives as novel RANKL-induced osteoclastogenesis inhibitors
20. ChemInform Abstract: Development of a New Indolocarbazole Anticancer Agent (NB-506)
21. Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists
22. ChemInform Abstract: Synthesis and Biological Activities of Topoisomerase I Inhibitors, 6-N-Amino Analogues of NB-506.
23. ChemInform Abstract: Synthesis and Biological Activities of NB-506 Analogues: Effects of the Positions of Two Hydroxyl Groups at the Indole Rings.
24. ChemInform Abstract: Isoxazolopyridone Derivatives as Allosteric Metabotropic Glutamate Receptor 7 Antagonists.
25. MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel
26. Synthesis and Biological Activities of Topoisomerase I Inhibitors, 6-Arylmethylamino Analogues of Edotecarin
27. FR177391, a New anti-Hyperlipidemic Agent from Serratia. Part 4. Target Identification and Validation by Chemical Genetic Approaches.
28. FR177391, a New anti‐Hyperlipidemic Agent from Serratia. Part 3. Microbial Conversion of FR177391 and Synthesis of FR177391 Derivatives for Its Target Protein Screening by Chemical Genetic Approaches.
29. FR177391, A New Anti-hyperlipidemic Agent from Serratia
30. FR177391, A New Anti-hyperlipidemic Agent from Serratia
31. An Efficient Synthesis of Cyclic β‐Amino Acid Derivatives as β‐Turn Mimetics.
32. Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors
33. Rational Approaches to Discovery of Orally Active and Brain-Penetrable Quinazolinone Inhibitors of Poly(ADP-ribose)polymerase
34. An efficient synthesis of the orally-active GpIIb/IIIa antagonist FR184764
35. Characterization of the anti-platelet actions of FK419, a novel non-peptide antagonist of platelet GPIIb/IIIa
36. Development of an orexin-2 receptor selective agonist, [Ala11, d-Leu15]orexin-B
37. A new class of type I protein geranylgeranyltransferase (GGTase I) inhibitor
38. ChemInform Abstract: Synthesis and Biological Activities of NB‐506 Analogues Modified at the Glucose Group.
39. Synthesis and biological activities of NB-506 analogues modified at the glucose group
40. In vivoAnti-tumor Activity of a Novel Indolocarbazole Compound, J-107088, on Murine and Human Tumors Transplanted into Mice
41. Substitution at the F-Ring N-Imide of the Indolocarbazole Antitumor Drug NB-506 Increases the Cytotoxicity, DNA Binding, and Topoisomerase I Inhibition Activities
42. Dess−Martin Periodinane Oxidation of Alcohols in the Presence of Stabilized Phosphorus Ylides: A Convenient Method for the Homologation of Alcohols via Unstable Aldehydes
43. Synthesis of Dissymmetric Indolocarbazole Glycosides Using the Mitsunobu Reaction at the Glycosylation Step
44. Synthesis of NB-506, A new anticancer agent
45. Design, synthesis, and evaluation of fibrinogen inhibitors, ω-(p-amidinophenoxy) alkanoylaspartic acid derivatives
46. Practical synthesis of indolopyrrolocarbazoles
47. Studies on Cerebral Protective Agents. X. Synthesis and Evaluation of Anticonvulsant Activities for Novel 4,5,6,7-Tetrahydrothieno(3,2-c)pyridines and Related Compounds.
48. Studies on Cerebral Protective Agents. IX. Synthesis of Novel 1,2,3,4-Tetrahydroisoquinolines as N-Methyl-D-aspartate Antagonists.
49. Studies on Cerebral Protective Agents. VII. Synthesis of Novel 4-Arylazole Derivatives with Anti-anoxic Activity.
50. Studies on Cerebral Protective Agents. VIII. Synthesis of 2-Aminothiazoles and 2-Thiazolecarboxamides with Anti-anoxic Activity.
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