Search

Your search keyword '"Okazaki, Nobuo"' showing total 269 results
Start Over Author "Okazaki, Nobuo"
269 results on '"Okazaki, Nobuo"'

2. Structure of HIV-1 Protease in Complex with Potent Inhibitor KNI-272 Determined by High-Resolution X-Ray and Neutron Crystallography

Author

Adachi, Motoyasu, Ohhara, Takashi, Kurihara, Kazuo, Tarmada, Taro, Honjo, Eijiro, Okazaki, Nobuo, Arai, Shigeki, Shoyama, Yoshinari, Kimura, Kaname, Matsumura, Hiroyoshi, Sugiyama, Shigeru, Adachi, Hiroaki, Takano, Kazufumi, Mori, Yusuke, Hidaka, Koushi, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki, Kuroki, Ryota, and Matthews, Brian W.

Published
2009
Full Text
View/download PDF

3. Systemic chemotherapy for hepatocellular carcinoma

Author

Okazaki, Nobuo, Okada, Shuichi, Nose, Haruhiko, Aoki, Kazunori, Tobe, Takayoshi, editor, Kameda, Haruo, editor, Okudaira, Masahiko, editor, Ohto, Masao, editor, Endo, Yasuo, editor, Mito, Michio, editor, Okamoto, Eizo, editor, Tanikawa, Kyuichi, editor, and Kojiro, Masamichi, editor

Published
1992
Full Text
View/download PDF

5. パリエジンバラプレスを用いた40GPaにおける高圧中性子回折実験のための手法開発

Author

Hattori, Takanori, Sano, Asami, Machida, Shinichi, Abe, Jun, Funakoshi, Kenichi, Arima, Hiroshi, and Okazaki, Nobuo

Abstract

We have developed a technique for neutron diffraction experiments at pressures up to 40 GPa using a Paris-Edinburgh press at the PLANET beamline in J-PARC. To increase the maximum accessible pressure, the diameter of the dimple for sample chamber at the top of the sintered diamond anvils is sequentially reduced from 4.0 mm to 1.0 mm. As a result, the maximum pressure increased and finally reached 40 GPa. By combining this technique with the beam optics which defines the gauge volume, diffraction patterns sufficient for full-structure refinements are obtainable at such pressures., パリエジンバラプレスを用いた40GPaでの高圧中性子回折実験の手法の開発をJ-PARCのPLANETビームラインにおいて行った。実験可能圧力限界を拡大するために、焼結ダイヤモンドアンビルの上部にある試料装填のためのくぼみの直径を4.0mmから1.0mmに順に小さくしていった。その結果、最大発生圧力は上昇し、最終的に40GPaに到達した。この技術を、回折に寄与する試料領域を制限できる光学系と組み合わせることによって、そのような高い圧力で、広いdレンジを用いた構造解析を行うのに十分な回折パターンを取得できるようになった。

Published
2019

10. Abstracts of selected papers presented at the 78th general meeting of the Japanese Society of Gastroenterology

Author

Kusano, Motoyasu, Sekiguchi, Toshikazu, Hanyu, Nobuyoshi, Aoki, Teruaki, Matsushima, Yasuhiro, Okamoto, Eizo, Takeda, Yasuo, Takeda, Ryoyu, Miyachi, Masahiko, Nimura, Yuji, Arai, Taidoh, Masuda, Jun, Tanaka, Masao, Ogawa, Yoshiaki, Ura, Kazuhide, Matsumoto, Teiji, Taniyama, K., Kurosawa, Susumu, Owyang, Chung, Baba, Hiroshi, Fujimura, Masaki, Hamada, Eiji, Shimada, Tadahito, Kabemura, Teppei, Chijiiwa, Yoshiharu, Sato, T., Koito, K., Matsuda, Hiroko, Kawasaki, Tsunehisa, Obara, Katsutoshi, Kasukawa, Reiji, Miyoshi, Hirofumi, Matsumoto, Akio, Yamamoto, Manabu, Ohmasa, Ryouji, Kokubu, Shigehiro, Shibata, Hisao, Tajiri, Takashi, Onda, Masahiko, Hashizume, Makoto, Sugimachi, Keizo, Kobayashi, Kenji, Shiozaki, Hitoshi, Fujisaki, Junko, Shimoda, Tadakazu, Hase, Satoshi, Tsukamoto, Yoshihisa, Atsumi, M., Konishi, H., Nakajo, Shinobu, Fujiyama, Yoshihide, Taruishi, Masaki, Ayabe, Tokiyoshi, Morise, Kimitomo, Yamaguchi, Takeo, Makiyama, Kazuya, Itsuno, Minoru, Matsui, T., Okabe, N., Okabe, Nobuo, Matsui, Toshiyuki, Sakatani, Arata, Koizumi, Koichi, Imai, Yutaka, Sugino, Yoshinori, Masaki, Tadahiko, Sawada, Toshio, Nishigami, Takashi, Satomi, Masamichi, Hatada, Yasumasa, Saito, Hiroshi, Kobayshi, Kiyonori, Katsumata, Tomoe, Sugimoto, Kenji, Itabashi, Tsukasa, Kitagawa, Motoji, Hayakawa, Tetsuo, Okazaki, Kazuichi, Yamamoto, Yasuro, Funakoshi, Akihiro, Miyasaka, Kyoko, Soejima, Kazuhiko, Kanda, Mikio, Sugiyama, Masanori, Kuroda, Akira, Inoue, Hisayuki, Bamba, Tadao, Hamanaka, Y., Suzuki, T., Suzuki, Mamoru, Hanyu, Fujio, Tamura, Katsuhiro, Nakase, Akira, Noguchi, M., Hiwatashi, N., Murata, Yuhji, Suzuki, Kazuo, Ohtani, Haruo, Watanabe, Yoshihisa, Zeniya, Mikio, Aizawa, Yoshio, Masumoto, T., Onji, M., Hamasaki, Keisuke, Nakata, Keisuke, Fukui, Hiroshi, Tsujii, Tadasu, Yamashiki, Masayoshi, Nishimura, Akira, Tsutsui, Hiroko, Mizoguchi, Yasuhiro, Kimura, Fumio, Miyazaki, Masaru, Kiyota, Keisuke, Inokuchi, Hideto, Yamamoto, Yoshihiro, Oka, Hiroshi, Horikoshi, Tsutomu, Sekiguchi, Toshikazu, Takayasu, H., Shirai, T., Hongo, Michio, Okuno, Yo, Okano, H., Aoyama, N., Ohsuki, Masao, Maeda, Kenji, Haruma, Ken, Sumii, Koji, Nakai, Yoshihide, Fukunaga, Mikihiko, Kaneko, Hiroshi, Morise, Kimitomo, Okumura, Toshikatsu, Uehara, Akira, Fukuda, Yoshihiro, Satomi, Masamichi, Joh, Takashi, Itoh, Makoto, Kitagawa, Yuko, Kitajima, Masaki, Iwao, Tadashi, Toyonaga, Atsushi, Nakamura, Masahiko, Oda, Masaya, Kawamura, Yukimitsu, Dohden, Kenji, Kamiyama, Yasuhiko, Matsuno, Seiki, Hirano, Morihisa, Otsuka, Sachio, Ito, Masahiro, Sekine, Ichiro, Ogihara, Tatsuo, Sato, Nobuhiro, Uehara, Akira, Namiki, Masayoshi, Sugiura, Nobuyuki, Ebara, Masaaki, Matsuo, Naoki, Uchida, Hideo, Okada, Shuichi, Okazaki, Nobuo, Tsujii, Hirohiko, Ohsuga, Toshiaki, Abe, M., Nagata, Y., Yamasaki, Susumu, Kosuge, Tomoo, Kitamoto, Mikiya, Nakanishi, Toshio, Ichikawa, Yuzo, Mizoguchi, Yasuhiro, Ohtake, Yoshio, Hirasawa, Hiroyuki, Sugihara, Junichi, Muto, Yasutoshi, Yasunaga, Mitsuru, Okita, Kiwamu, Ukida, Minoru, Tsuji, Takao, Isai, Hideya, Uchino, Junichi, Suzuki, Katsuhiko, Komatsu, Kanji, Ohtomo, Yumiko, Idezuki, Yasuo, Sakuramachi, Shunji, Kimura, Taizo, Kitano, Seigo, Sugimachi, Keizo, Moriyama, Masaaki, Yazaki, Yasuyuki, and Saito, Takashige

Published
1993
Full Text
View/download PDF

11. Abstracts of selected papers presented at the 33rd annual meeting of the japanese society of gastroenterology

Author

Kubo, Shoji, Kinoshita, Hiroaki, Mukai, Hidekazu, Nakajima, Masatsugu, Kamei, Akira, Horiguchi, Yuji, Sai, Jinkan, Ariyama, Jo, Shiraki, Shigehiro, Takeuchi, Toshihiko, Hamada, Minoru, Ito, Nobuyasu, Komatsu, Eiji, Isobe, Yoshinori, Sakata, Kenji, Yoshida, Hiroshi, Kiso, Shinichi, Kawata, Sumio, Tominaga, Tsuyoshi, Ohuchi, Kiyoaki, Nemoto, A., Mizumoto, R., Tsunoda, Takafumi, Nitta, Yoshiro, Lee, Kwang Choon, Yamazaki, Osamu, Koike, K., Kobayashi, K., Suyama, Tetsuji, Tsubai, Fumiyo, Kashimura, Hiromasa, Nakahara, Akira, Takahashi, Shuji, Yoshikawa, Toshikazu, Ajitsu, Shin, Takeda, Hiroaki, Hoshino, Etsuo, Noritsugu, Umeda, Sasaki, Kazuaki, Hirata, Koichi, Mochida, Satoshi, Fujiwara, Kenji, Yamashiki, Masayoshi, Nishimura, Akira, Yamauchi, Hiroshi, Ishii, Hiromasa, Ookubo, Hitoshi, Arakawa, Yasuyuki, Oka, Hiroko, Yamamoto, Sukeo, Aihara, Naoki, Tazuma, Susumu, Mizuno, Shuichi, Hasegawa, Itaru, Mizoguchi, Yasuhiro, Kobayashi, Kenzo, Asaka, Masaki, Ozaki, Makoto, Kurihara, Norimitsu, Kakehashi, R., Ikoma, J., Tokumura, Hiromi, Matsushiro, Takashi, Kanemaki, Naoto, Okushima, Kazumu, Shinagawa, Nagao, Yura, Jiro, Segawa, Kose, Suzuki, Takashi, Hirano, Hiroyuki, Koizumi, Masaru, Miura, Satoru, Shiraishi, Taizo, Tanaka, Masatoshi, Tanikawa, Kyuichi, Shibata, J., Fujiyama, S., Matsuoka, Shinichi, Uchino, Junichi, Kawamura, Eisuke, Okamoto, Eizo, Kamimoto, Yukio, Tashiro, Seiki, Nagaiwa, Jiro, Ariyama, Jo, Kinoshita, Hisafumi, Nakayama, Toshimichi, Kayahara, Masato, Nagakawa, Takukazu, Kamisawa, Terumi, Isawa, Tomoaki, Hatori, Takashi, Imaizumi, Toshihide, Yata, Mitsuhiro, Miyoshi, Hirofumi, Furuya, Shinnichi, Takaaki, Junpei, Higashino, Masayuki, Kinoshita, Hiroaki, Niwa, Yasumasa, Segawa, Kose, Yoshino, Junji, Wakabayashi, Takao, Haruma, Ken, Kishimoto, Shinya, Kawano, Sunao, Fusamoto, Hideyuki, Higuchi, K., Arakawa, T., Yoshioka, Hideyuki, Kita, Tom, Taniguchi, Yushi, Kimura, Ken, Irie, Akira, Toyonaga, Atsushi, Okuno, Masahiro, Ikehara, Teruyuki, Kanazawa, Kyotaro, Ezaki, Yukiyoshi, Maruyama, Kyohei, Fukuda, Shin-ichiro, Horj, Shinji, Satomi, Masamichi, Iwane, Satoru, Munakata, Akihiro, Hayashi, Shigekazu, Arakawa, Akira, Inoue, Fumihiko, Furukawa, Hiroo, Kasugai, Hiroshi, Okuda, Shigeru, Saitoh, Satoshi, Kumada, Hiromitsu, Takashima, S., Nakamura, K., Kokura, Satoshi, Yoshikawa, Toshikazu, Okada, Shuichi, Okazaki, Nobuo, Yoshikawa, Masaharu, Ebara, Masaaki, Okabe, Hideo, Nakano, Satoshi, Urabe, Takeshi, Unoura, Masashi, Kobayashi, Kenichi, Aoki, Yoshinori, Tanikawa, Kyuich, Okazaki, Masatoshi, Higashihara, Hideyuki, Nagashima, Toru, Isono, Kaichi, Ueda, Masakazu, Tsuzuki, Toshiharu, Sasaki, Yo, Imaoka, Shingi, Kakazu, Tohru, Makuuchi, Masatoshi, Takayama, Tadatoshi, Kosuge, Tomoo, Yamanaka, Naoki, and Okamoto, Eizo

Published
1993
Full Text
View/download PDF

13. Abstracts of Selected Papers Presented at the 31st Annual Meeting of the Japanese Society of Gastroenterology

Author

Takeda, Shin, Nakao, Akimasa, Kanoh, Makoto, Matsuo, Yutaka, Takemori, Yasuhiro, Sawabu, Norio, Nakagoe, Tohru, Okuda, Hiroaki, Obata, Hiroshi, Ono, Minoru, Sekiya, Chihiro, Hayashi, Norio, Kamada, Takenobu, Imawari, Michio, Kaieda, Takeji, Yamaguchi, Toshiharu, Takahashi, Toshio, Tsujisaki, Masayuki, Imai, Kohzoh, Tatsuta, Masaharu, Okuda, Shigeru, Yoshikawa, Toshikazu, Kondo, Motoharu, Kawano, Sunao, Sato, Nobuhiro, Yasue, Naoji, Itoh, Makoto, Mutoh, Hiroyuki, Terano, Akira, Kitahara, Tetsuji, Suzuki, Koichi, Suematsu, Makoto, Ishii, Hiromasa, Ogata, Itsuro, Fujiwara, Kenji, Taoka, Hiroki, Mizumoto, Ryuji, Oguchi, Hisao, Koiwai, Toshihiko, Nonaka, Atsushi, Manabe, Tadao, Inoue, Masayasu, Izumi, Tsuguhiko, Kurihara, Minoru, Sakata, Yuh, Kawakami, Kiyoshi, Okazaki, Nobuo, Yosimori, Masayoshi, Mizuno, Shuichi, Okuse, S., Miyata, Nobuyuki, Namatame, Kimio, Watanabe, Naoki, Kohgo, Yutaka, Yoshida, Mamoru, Saito, Shozo, Namiki, Akiyoshi, Kitamori, Shigeru, Saitoh, Yuusuke, Ishii, Hiroyasu, Tatsuta, Masaharu, Sugihara, Tamotsu, Hirao, Masanori, Masahiro, Mitake, Mitsugu, Yamada, Harima, Kenzo, Aibe, Tuyoshi, Mukai, Hidekazu, Yasuda, Kenjiro, Nagaiwa, J., Ariyama, J., Itoh, Masaki, and Kajiyama, Goro

Published
1991
Full Text
View/download PDF

14. Malignant transformation of adenomatous hyperplasia to hepatocellular carcinoma

Author

Takayama, Tadatoshi, Makuuchi, Masatoshi, Hirohashi, Setsuo, Sakamoto, Michiie, Okazaki, Nobuo, Takayasu, Kenichi, Kosuge, Tomoo, Motoo, Yoshiharu, Yamazaki, Susumu, and Hasegawa, Hiroshi

Subjects
Liver cancer -- Development and progression, Hyperplasia -- Development and progression, Liver cancer -- Risk factors, Hyperplasia -- Complications
Published
1990

18. Materials and Life Science Experimental Facility at the Japan Proton Accelerator Research Complex III: Neutron Devices and Computational and Sample Environments

Author

Sakasai, Kaoru, primary, Satoh, Setsuo, additional, Seya, Tomohiro, additional, Nakamura, Tatsuya, additional, Toh, Kentaro, additional, Yamagishi, Hideshi, additional, Soyama, Kazuhiko, additional, Yamazaki, Dai, additional, Maruyama, Ryuji, additional, Oku, Takayuki, additional, Ino, Takashi, additional, Kira, Hiroshi, additional, Hayashida, Hirotoshi, additional, Sakai, Kenji, additional, Itoh, Shinichi, additional, Suzuya, Kentaro, additional, Kambara, Wataru, additional, Kajimoto, Ryoichi, additional, Nakajima, Kenji, additional, Shibata, Kaoru, additional, Nakamura, Mitsutaka, additional, Otomo, Toshiya, additional, Nakatani, Takeshi, additional, Inamura, Yasuhiro, additional, Suzuki, Jiro, additional, Ito, Takayoshi, additional, Okazaki, Nobuo, additional, Moriyama, Kentaro, additional, Aizawa, Kazuya, additional, Ohira-Kawamura, Seiko, additional, and Watanabe, Masao, additional

Published
2017
Full Text
View/download PDF

23. Structure of a highly acidic β-lactamase from the moderate halophileChromohalobactersp. 560 and the discovery of a Cs+-selective binding site

Author

Arai, Shigeki, primary, Yonezawa, Yasushi, additional, Okazaki, Nobuo, additional, Matsumoto, Fumiko, additional, Shibazaki, Chie, additional, Shimizu, Rumi, additional, Yamada, Mitsugu, additional, Adachi, Motoyasu, additional, Tamada, Taro, additional, Kawamoto, Masahide, additional, Tokunaga, Hiroko, additional, Ishibashi, Matsujiro, additional, Blaber, Michael, additional, Tokunaga, Masao, additional, and Kuroki, Ryota, additional

Published
2015
Full Text
View/download PDF

25. Cardiopulmonary arrest in pregnancy with schizophrenia: a case report

Author

Kudo, Takako, primary, Kaga, Akimune, additional, Akagi, Kozo, additional, Iwahashi, Hideki, additional, Makino, Hiromitsu, additional, Watanabe, Yoko, additional, Kawamura, Takae, additional, Sato, Taiju, additional, Shinozaki, Tsuyoshi, additional, Miwa, Shinya, additional, Okazaki, Nobuo, additional, Kure, Shigeo, additional, and Nakae, Shingi, additional

Published
2014
Full Text
View/download PDF

37. Clinical and radiologic assessments of the results of hepatectomy for small hepatocellular carcinoma and therapeutic arterial embolization for postoperative recurrence

Author

Takayasu, Kenichi, Muramatsu, Yukio, Moriyama, Noriyuki, Hasegawa, Hiroshi, Makuuchi, Masatoshi, Okazaki, Nobuo, Hirohashi, Setsuo, and Tsugane, Shoichiro

Subjects
Liver, Liver cancer, Surgery -- Evaluation, Health
Abstract

The advent of modern medical imaging techniques has improved the ability to diagnose small hepatocellular carcinoma (s-HCC), a cancer of the liver. With rapid, reliable diagnosis, more patients are being treated surgically for this tumor. Patients with s-HCC were followed-up postoperatively, for periods ranging from nine months to more than nine years, to determine the natural history of the disease and to evaluate the effectiveness of introducing an arterial embolus, or a block in an artery, as treatment for recurring tumors in the liver. Of the 123 patients followed, 54.2 percent had a recurrence of s-HCC tumor in their liver an average of 14.9 months after surgery. Of the 48 recurrences diagnosed by imaging techniques, 12 were negative for alpha-fetoprotein, which is usually regarded as a blood-borne marker for liver disease. This demonstrates the improved reliability of the imaging techniques. Sixteen patients were lost to complete follow-up. Of the remaining patients with s-HCC, the 5-year survival rate was 48.9 percent for those without tumor recurrence and 11.0 percent for patients with recurrence. Embolization treatment of the recurring tumors seemed to provide some benefit; for patients with recurring liver tumors, the survival rate was 0 percent without embolization treatment and 14.9 percent among those who received the treatment. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1989

42. Structure of a highly acidic β-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs+-selective binding site.

Author

Arai, Shigeki, Yonezawa, Yasushi, Okazaki, Nobuo, Matsumoto, Fumiko, Shibazaki, Chie, Shimizu, Rumi, Yamada, Mitsugu, Adachi, Motoyasu, Tamada, Taro, Kawamoto, Masahide, Tokunaga, Hiroko, Ishibashi, Matsujiro, Blaber, Michael, Tokunaga, Masao, and Kuroki, Ryota

Subjects
BETA lactamases, CESIUM isotopes, STRONTIUM isotopes, BINDING sites, CRYSTAL structure, X-ray diffraction, RADIOISOTOPES
Abstract

Environmentally friendly absorbents are needed for Sr2+ and Cs+, as the removal of the radioactive Sr2+ and Cs+ that has leaked from the Fukushima Nuclear Power Plant is one of the most important problems in Japan. Halophilic proteins are known to have many acidic residues on their surface that can provide specific binding sites for metal ions such as Cs+ or Sr2+. The crystal structure of a halophilic β-lactamase from Chromohalobacter sp. 560 (HaBLA) was determined to resolutions of between 1.8 and 2.9 Å in space group P31 using X-ray crystallography. Moreover, the locations of bound Sr2+ and Cs+ ions were identified by anomalous X-ray diffraction. The location of one Cs+-specific binding site was identified in HaBLA even in the presence of a ninefold molar excess of Na+ (90 m M Na+/10 m M Cs+). From an activity assay using isothermal titration calorimetry, the bound Sr2+ and Cs+ ions do not significantly affect the enzymatic function of HaBLA. The observation of a selective and high-affinity Cs+-binding site provides important information that is useful for the design of artificial Cs+-binding sites that may be useful in the bioremediation of radioactive isotopes. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results