159 results on '"Okiyoneda, Tsukasa"'
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2. Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis
3. HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains
4. Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters
5. Enhanced CFTR modulator efficacy in ΔF508 CFTR mouse organoids by ablation of RFFL ubiquitin ligase
6. HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
7. Mechanism-based corrector combination restores ΔF508-CFTR folding and function.
8. The multiple ubiquitination mechanisms in CFTR peripheral quality control
9. Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment.
10. UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR.
11. The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure
12. The RFFL antisense oligonucleotides improve the function of CFTR mutants associated with cystic fibrosis.
13. Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane
14. N-Glycans Are Direct Determinants of CFTR Folding and Stability in Secretory and Endocytic Membrane Traffic
15. The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)
16. Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice
17. Endocytic Sorting of CFTR Variants Monitored by Single-Cell Fluorescence Ratiometric Image Analysis (FRIA) in Living Cells
18. CFTR Folding Consortium: Methods Available for Studies of CFTR Folding and Correction
19. MECHANISM-DRIVEN CORRECTOR SELECTION STRATEGY TO RESCUE THE ΔF508 CFTR FOLDING DEFECT: S8.1
20. Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
21. MOLECULAR ASPECTS OF NON-NATIVE CFTR ELIMINATION FROM THE CELL SURFACE: S4.3
22. CONFORMATIONAL STATE AS A TRAFFICKING DETERMINANT OF CFTR: S15.4
23. Characterization of the Trafficking Pathway of Cystic Fibrosis Transmembrane Conductance Regulator in Baby Hamster Kidney Cells
24. The integral function of endocytic recycling compartment is regulated by RFFL-mediated ubiquitination of Rab11 effectors
25. ELISA Based Protein Ubiquitylation Measurement
26. Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer
27. Chaperone-Independent Peripheral Quality Control of CFTR by RFFL E3 Ligase
28. Characterization of CFTR expression in a human pulmonary mucoepidermoid carcinoma cell line, NCI-H292 cells
29. Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell
30. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.
31. Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane
32. Fixing cystic fibrosis by correcting CFTR domain assembly
33. STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein
34. Correction of Both NBD1 Energetics and Domain Interface Is Required to Restore ΔF508 CFTR Folding and Function
35. Protein quality control at the plasma membrane
36. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis
37. Revisiting the Role of Cystic Fibrosis Transmembrane Conductance Regulator and Counterion Permeability in the pH Regulation of Endocytic Organelles
38. Reduced Cell Surface Stability Of Rescued Herg Trafficking Mutants
39. Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and ΔF508 CFTR
40. Phosphatidic acid metabolism regulates the intracellular trafficking and retrotranslocation of CFTR
41. Cell surface dynamics of CFTR: The ins and outs
42. Curcumin enhances cystic fibrosis transmembrane regulator expression by down-regulating calreticulin
43. Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator
44. Calreticulin facilitates the cell surface expression of ABCG5/G8
45. Calreticulin Negatively Regulates the Cell Surface Expression of Cystic Fibrosis Transmembrane Conductance Regulator
46. Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cells
47. Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells
48. Sp1-dependent regulation of Myeloid Elf-1 like factor in human epithelial cells
49. Sp1 is involved in the transcriptional activation of lysozyme in epithelial cells
50. ΔF508 CFTR Pool in the Endoplasmic Reticulum Is Increased by Calnexin Overexpression
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