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686 results on '"Okubo, Kimihiro"'

1. Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)

Author

Bousquet, Jean, Schünemann, Holger J., Sousa-Pinto, Bernardo, Zuberbier, Torsten, Togias, Alkis, Samolinski, Boleslaw, Bedbrook, Anna, Czarlewski, Wienczyslawa, Hofmann-Apitius, Martin, Litynska, Justyna, Vieira, Rafael José, Anto, Josep M., Fonseca, Joao A., Brozek, Jan, Bognanni, Antonio, Brussino, Luisa, Canonica, G. Walter, Cherrez-Ojeda, Ivan, Cruz, Alvaro A., Vecillas, Leticia de las, Dykewicz, Mark, Gemicioglu, Bilun, Giovannini, Mattia, Haahtela, Tari, Jacobs, Marc, Jacomelli, Cristina, Klimek, Ludger, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Louis, Gilles, Lourenço, Olga, Leemann, Lucas, Morais-Almeida, Mario, Neves, Ana Luisa, Nadeau, Kari C., Nowak, Artur, Palamarchuk, Yuliia, Palkonen, Susanna, Papadopoulos, Nikolaos G., Parmelli, Elena, Pereira, Ana Margarida, Pfaar, Oliver, Regateiro, Frederico S., Savouré, Marine, Taborda-Barata, Luis, Toppila-Salmi, Sanna K., Torres, Maria J., Valiulis, Arunas, Ventura, Maria Teresa, Williams, Sian, Yepes-Nuñez, Juan J., Yorgancioglu, Arzu, Zhang, Luo, Zuberbier, Jaron, Abdul Latiff, Amir Hamzah, Abdullah, Baharudin, Agache, Ioana, Al-Ahmad, Mona, Al-Nesf, Maryam Ali, Al Shaikh, Nada A., Amaral, Rita, Ansotegui, Ignacio J., Asllani, Julijana, Balotro-Torres, Maria Cristina, Bergmann, Karl-Christian, Bernstein, Jonathan A., Bindslev-Jensen, Carsten, Blaiss, Michael S., Bonaglia, Cristina, Bonini, Matteo, Bossé, Isabelle, Braido, Fulvio, Caballero-Fonseca, Fernan, Camargos, Paulo, Carreiro-Martins, Pedro, Casale, Thomas, Castillo-Vizuete, José-Antonio, Cecchi, Lorenzo, Teixeira, Maria do Ceu, Chang, Yoon-Seok, Loureiro, Claudia Chaves, Christoff, George, Ciprandi, Giorgio, Cirule, Ieva, Correia-de-Sousa, Jaime, Costa, Elisio M., Cvetkovski, Biljana, de Vries, Govert, Del Giacco, Stefano, Devillier, Philippe, Dokic, Dejan, Douagui, Habib, Durham, Stephen R., Enecilla, Maria Lourdes, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean-François, Gawlik, Radoslaw, Gereda, Jose E., Gil-Mata, Sara, Giuliano, Antonio F.M., Gotua, Maia, Gradauskiene, Brigita, Guzman, Maria Antonieta, Hossny, Elham, Hrubiško, Martin, Iinuma, Tomohisa, Irani, Carla, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Jartti, Tuomas, Jeseňák, Miloš, Julge, Kaja, Jutel, Marek, Kaidashev, Igor, Bennoor, Kazi S., Khaltaev, Nicolai, Kirenga, Bruce, Kraxner, Helga, Kull, Inger, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Kurchenko, Andriy, La Grutta, Stefania, Lane, Stephen, Miculinic, Neven, Lee, Sang Min, Le Thi Tuyet, Lan, Lkhagvaa, Battur, Louis, Renaud, Mahboub, Bassam, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Eric, Milenkovic, Branislava, Mohammad, Yousser, Moniuszko, Marcin, Montefort, Stephen, Moreira, Andre, Moreno, Pablo, Mullol, Joaquim, Nadif, Rachel, Nakonechna, Alla, Navarro-Locsin, Cecilia Gretchen, Neffen, Hugo E., Nekam, Kristof, Niedoszytko, Marek, Nunes, Elizabete, Nyembue, Dieudonné, O’Hehir, Robyn, Ollert, Markus, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimihiro, Olze, Heidi, Padukudru, Mahesh Anand, Palomares, Oscar, Pali-Schöll, Isabella, Panzner, Petr, Palosuo, Kati, Park, Hae S., Passalacqua, Giovanni, Patella, Vincenzo, Pawankar, Ruby, Pétré, Benoît, Pitsios, Constantinos, Plavec, Davor, Popov, Todor A., Puggioni, Francesca, Quirce, Santiago, Raciborski, Filip, Ramonaité, Agné, Recto, Marysia, Repka-Ramirez, Susana, Roberts, Graham, Robles-Velasco, Karla, Roche, Nicolas, Rodriguez-Gonzalez, Monica, Romualdez, Joel A., Rottem, Menachem, Rouadi, Philip W., Salapatas, Marianella, Sastre, Joaquin, Serpa, Faradiba S., Sayah, Zineb, Scichilone, Nicola, Senna, Gianenrico, Sisul, Juan Carlos, Solé, Dirceu, Soto-Martinez, Manuel E., Sova, Milan, Sozinova, Olga, Stevanovic, Katarina, Ulrik, Charlotte Suppli, Szylling, Anna, Tan, Frances M., Tantilipikorn, Pongsakorn, Todo-Bom, Ana, Tomic-Spiric, Vesna, Tsaryk, Vladyslav, Tsiligianni, Ioanna, Urrutia-Pereira, Marilyn, Rostan, Marylin Valentin, Sofiev, Mikhail, Valovirta, Erkka, Van Eerd, Michiel, Van Ganse, Eric, Vasankari, Tuula, Vichyanond, Pakit, Viegi, Giovanni, Wallace, Dana, Wang, De Yun, Waserman, Susan, Wong, Gary, Worm, Margitta, Yusuf, Osman M., Zaitoun, Fares, and Zidarn, Mihaela

Published
2024
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10. Detailed Clinical Features of PTPRQ-Associated Hearing Loss Identified in a Large Japanese Hearing Loss Cohort

Author

Sakuma, Naoko, primary, Nishio, Shin-ya, additional, Goto, Shin-ichi, additional, Honkura, Yohei, additional, Oda, Kiyoshi, additional, Takeda, Hidehiko, additional, Kobayashi, Marina, additional, Kumakawa, Kozo, additional, Iwasaki, Satoshi, additional, Takahashi, Masahiro, additional, Ito, Taku, additional, Arai, Yasuhiro, additional, Isono, Yasuhiro, additional, Obara, Natsuko, additional, Matsunobu, Takeshi, additional, Okubo, Kimihiro, additional, and Usami, Shin-ichi, additional

Published
2024
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17. Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet

Author

Gotoh, Minoru, Okubo, Kimihiro, Yuta, Atsushi, Ogawa, Yukiko, Nagakura, Hitoshi, Ueyama, Shigehiro, Ueyama, Tomoyo, Kawashima, Kayoko, Yamamoto, Masashi, Fujieda, Shigeharu, Sakashita, Masafumi, Sakamoto, Hirokazu, Iwasaki, Naruhito, Mori, Eri, Endo, Tomonori, Ohta, Nobuo, Kitazawa, Hiroshi, Okano, Mitsuhiro, Asako, Mikiya, Takada, Masami, Terada, Tetsuya, Inaka, Yuko, Yonekura, Syuji, Matsuoka, Tomokazu, Kaneko, Shinya, Hata, Hiroki, Hijikata, Nagisa, Tanaka, Hisataka, Masuyama, Keisuke, and Okamoto, Yoshitaka

Published
2020
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23. Long-term safety of subcutaneous immunotherapy with TO-204 in Japanese patients with house dust mite-induced allergic rhinitis and allergic bronchial asthma: Multicenter, open label clinical trial

Author

Fujisawa, Takao, Shimoda, Terufumi, Masuyama, Keisuke, Okubo, Kimihiro, Honda, Kohei, Okano, Mitsuhiro, Katsunuma, Toshio, Urisu, Atsuo, Kondo, Yasuto, Odajima, Hiroshi, Kurihara, Kazuyuki, Nagata, Makoto, Taniguchi, Masami, Taniuchi, Shoichiro, Doi, Satoru, Matsumoto, Tomoshige, Hashimoto, Shoji, Tanaka, Akihiko, Natsui, Kensuke, Abe, Nahoko, and Ozaki, Hideki

Published
2018
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26. Complementary and alternative medicine for allergic rhinitis in Japan

Author

Yonekura, Syuji, Okamoto, Yoshitaka, Sakurai, Daiju, Sakurai, Toshioki, Iinuma, Tomohisa, Yamamoto, Heizaburou, Hanazawa, Toyoyuki, Horiguchi, Shigetoshi, Kurono, Yuichi, Honda, Kohei, Majima, Yuichi, Masuyama, Keisuke, Takeda, Noriaki, Fujieda, Shigeharu, Okano, Mitsuhiro, Ogino, Satoshi, and Okubo, Kimihiro

Published
2017
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31. Barrier Factors of Adherence to Dupilumab Self-Injection for Severe Allergic Disease: A Non-Interventional Open-Label Study

Author

Hosoya,Kei, Komachi,Taro, Masaki,Katsunori, Suzaki,Isao, Saeki,Hidehisa, Kanda,Naoko, Nozaki,Makoto, Kamide,Yosuke, Matsuwaki,Yoshinori, Kobayashi,Yoshiki, Ogino,Eriko, Osada,Shin-Ichi, Usukura,Norihiro, Kurumagawa,Toshikazu, Ninomia,Junya, Asako,Mikiya, Nakamoto,Keitaro, Yokoi,Hidenori, Ohyama,Manabu, Tanese,Keiji, Kanzaki,Sho, Fukunaga,Koichi, Ebisawa,Motohiro, Okubo,Kimihiro, Hosoya,Kei, Komachi,Taro, Masaki,Katsunori, Suzaki,Isao, Saeki,Hidehisa, Kanda,Naoko, Nozaki,Makoto, Kamide,Yosuke, Matsuwaki,Yoshinori, Kobayashi,Yoshiki, Ogino,Eriko, Osada,Shin-Ichi, Usukura,Norihiro, Kurumagawa,Toshikazu, Ninomia,Junya, Asako,Mikiya, Nakamoto,Keitaro, Yokoi,Hidenori, Ohyama,Manabu, Tanese,Keiji, Kanzaki,Sho, Fukunaga,Koichi, Ebisawa,Motohiro, and Okubo,Kimihiro

Abstract

Kei Hosoya,1 Taro Komachi,2,* Katsunori Masaki,3,* Isao Suzaki,4 Hidehisa Saeki,5 Naoko Kanda,6 Makoto Nozaki,7 Yosuke Kamide,8 Yoshinori Matsuwaki,9 Yoshiki Kobayashi,10 Eriko Ogino,11 Shin-Ichi Osada,12 Norihiro Usukura,13 Toshikazu Kurumagawa,14 Junya Ninomia,15 Mikiya Asako,16 Keitaro Nakamoto,17 Hidenori Yokoi,18 Manabu Ohyama,19 Keiji Tanese,3 Sho Kanzaki,3 Koichi Fukunaga,3 Motohiro Ebisawa,8 Kimihiro Okubo13 1Nippon Medical School, Musashi Kosugi Hospital, Kanagawa, Japan; 2Department of Otolaryngology, Nippon Medical School, Chiba Hokusoh Hospital, Inzai, Chiba, Japan; 3Keio Allergy Center, Keio University Hospital, Tokyo, Japan; 4Department of Otorhinolaryngology, Head and Neck Surgery, Showa University, School of Medicine, Tokyo, Japan; 5Department of Dermatology, Nihon Medical School, Tokyo, Japan; 6Department of Dermatology, Nippon Medical School, Chiba Hokusoh Hospital, Inzai, Chiba, Japan; 7Wakaba-Hifuka Clinic, Tokyo, Japan; 8National Hospital Organization Sagamihara National Hospital, Clinical Research Center for Allergy and Rheumatology, Kanagawa, Japan; 9Matsuwaki Clinic Shinagawa, Tokyo, Japan; 10Allergy Center, Kansai Medical University, Hirakata, Japan; 11Kyoto Nose and Allergy Clinic, Kyoto, Japan; 12Department of Dermatology, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan; 13Department of Otolaryngology, Head and Neck Surgery, Nippon Medical School Hospital, Tokyo, Japan; 14Minamiosawa Medical Plaza, Tokyo, Japan; 15Nagase Clinic of Dermatology, Tokyo, Japan; 16Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Osaka, Japan; 17Department of Respiratory Medicine, Kyorin University Faculty of Medicine, Tokyo, Japan; 18Department of Otolaryngology, Head and Neck Surgery, Kyorin University Faculty of Medicine, Tokyo, Japan; 19Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan*These authors contributed equally to this workCorrespondence: Kei Hosoya, Nippon

Published
2023

34. スギ花粉舌下免疫療法の長期治療効果

Author

Hamada, Satoko, primary, Kobayashi, Yoshiki, additional, Sakamoto, Daiki, additional, Shimamura, Akihiro, additional, Kuroda, Kazumichi, additional, Kawachi, Risaki, additional, Kanda, Akira, additional, Asako, Mikiya, additional, Gotoh, Minoru, additional, Okubo, Kimihiro, additional, Tomoda, Koichi, additional, and Iwai, Hiroshi, additional

Published
2023
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35. Barrier Factors of Adherence to Dupilumab Self-Injection for Severe Allergic Disease: A Non-Interventional Open-Label Study

Author

Hosoya, Kei, primary, Komachi, Taro, additional, Masaki, Katsunori, additional, Suzaki, Isao, additional, Saeki, Hidehisa, additional, Kanda, Naoko, additional, Nozaki, Makoto, additional, Kamide, Yosuke, additional, Matsuwaki, Yoshinori, additional, Kobayashi, Yoshiki, additional, Ogino, Eriko, additional, Osada, Shin-Ichi, additional, Usukura, Norihiro, additional, Kurumagawa, Toshikazu, additional, Ninomia, Junya, additional, Asako, Mikiya, additional, Nakamoto, Keitaro, additional, Yokoi, Hidenori, additional, Ohyama, Manabu, additional, Tanese, Keiji, additional, Kanzaki, Sho, additional, Fukunaga, Koichi, additional, Ebisawa, Motohiro, additional, and Okubo, Kimihiro, additional

Published
2023
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38. Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL hypothesis

Author

Bousquet, Jean, Melén, Erik, Haahtela, Tari, Koppelman, Gerard, Togias, Alkis, Valenta, Rudolf, Akdis, Cezmi, Czarlewski, Wienczyslawa, Rothenberg, Marc, Valiulis, Arunas, Wickman, Magnus, Vichyanond, Pakit, Moniuszko, Marcin, Ėmužytė, Regina, Bush, Andrew, Chu, Derek K, Viegi, Giovanni, Wallace, Dana, Durham, Stephen, Wang, De Yun, Vandenplas, O., Just, Jocelyne, Carlsen, Karin C. Lodrup, Passalacqua, Giovanni, Williams, Siân, Linnemann, Désirée Larenas, Loureiro, Cláudia Chaves, Sagara, Hironori, Worm, Margitta, Yiallouros, Panayiotis, Yusuf, Osman, Zaitoun, Fares, Bonini, Matteo, Hrubiško, Martin, Cingi, C., Dykewicz, Mark, Zernotti, Mario, Calderon, Moises, Halpin, David M.G., Zidarn, Mihaela, Patella, Vincenzo, Sheikh, Aziz, Zuberbier, Jaron, Papadopoulos, Nikolaos, Louis, Renaud, Suppli Ulrik, Charlotte, Fonseca, João P., Zuberbier, Torsten, Anto, M. J., Costa, Elisio, Eiwegger, Thomas, Bosnic-Anticevich, Sinthia, Cruz, Alvaro, Sousa, Jaime Correia de, Louis-Philippe, Boulet, Erhola, Marina, Cardona, Victoria, Carr, Warner, Gemicioglu, Bilun, Pawankar, Ruby, Fokkens, Wytske, Calvo, Mário, Garcia-Aymerich, J., Mäkelä, Mika J., Hofmann, Maja Ann, Klimek, Ludger, Makris, Michael, Mohamed Sayed, Zeinab, Maurer, Marcus, D'Amato, G., Momas, Isabelle, Siroux, Valérie, Almeida, Mário Morais, Corrigan, Chris, Mullol, Joaquim, Montefort, Stephen, Jutel, Marek, Pham Thi, Nhan, Hossny, Elham, Akdis, Mubeccel, Pfaar, Oliver, Ventura, Maria Teresa, Regateiro, Frederico S., Bindslev-Jensen, Carsten, Ring, Johannes, Bustamante, Mariona, Pinto, Bernardo Sousa, Kaidashev, Igor, Guerra, Stefano, Standl, Marie, Sunyer, J., Keil, Thomas, Barata, Luís Taborda, Camargos, Paulo, Weiss, Scott, Naclerio, Robert, Yorgancıoglu, Arzu, Zhang, Luo, Nadeau, Kari, Abdul Latiff, Amir, Aberer, Werner, Heinrich, Joachim, Sisul, Juan, Nunes, Elizabete, Plavec, Davor, Agache, Ioana, Al-Ahmad, Mona, Serpa, Faradiba, Alobid, Isam, Kalayci, Omer, Giacco, S. Del, Fiocchi, Alessandro, Ansotegui Zubeldia, Ignacio Javier, Custovic, Adnan, Martins, Pedro Carreiro, Rouadi, Philip, Arshad, Syed Hasan, Asayag, Estrella, Bárbara, Cristina, Abdullah, Baharudin, Tomazic, Peter Valentin, Popov, T. A., Sayah, Zineb, Lkhagvaa, Battur, Nyembue Tshipukane , Dieudonne, Thomas, Mike, Bennoor, Kazi Saifuddin, Fyhrquist, Nanna Theresia, Irani, Carla, Berghea, Elena Camelia, De Blay, Frédéric, Toppila-Salmi, Sanna Katriina, Bergmann, Karl-Christian, Bernstein, D., Bewick, M., Casale, Thomas, Scheire, Sophie, Bumbacea, Roxana Silvia, Cepeda Sarabia, Alfonso, Puggioni, Francesca, Chandrasekharan, Ramanathan, Ohta, Ken, Okubo, Kimihiro, Charpin, Denis, Gomez, R Maximiliano, Chen, Y. Z., O'Hehir, Robyn, Cherrez Ojeda, Ivan, Bedbrook, Anna, To, Teresa, Devillier, Philippe, Schmid-Grendelmeier, Peter, Didier, Alain, Repka-Ramirez, María Susana, Teixeira, Maria Do Céu, Ispayeva, Zhanat, Dokic, Dejan, Quirce, Santiago, Douagui , Habib, Ivancevich, Juan Carlos, Gotua, Maia, Todo-Bom, Ana, Blain, Hubert, Guzman, Maria Antonieta, Kalyoncu, Ali Fuat, Hagemann, Jan, Buhl, Roland, Hamamah, Samir, Caraballo, Luis, Jares, Edgardo, Chivato, Tomás, Jartti, Tuomas, Jassem, Ewa, Christoff, George, Julge, Kalev, Ogulur, Ismail, Kardas, Przemyslaw, Doulaptsi, Maria, Kirenga, Bruce, Helga, Kraxner, Kull, Inger, Kulus, Marek, Daniel, Aguilar, Shamji, Mohamed, Kuna, Piotr, Nadif, Rachel, La Grutta, Stefania, Brightling, Chris, Samoliński, Bolesław, Lau, Susanne, Cordeiro, Carlos Manuel Da Silva Robalo, Solé, Dirceu, Le Thi Tuyet, Lan, Recto, Marysia, Ouedraogo, Solange, Halken, Susanne, Levin, Michael, Lipworth, Brian, Lourenço, Olga, Mahboub, Bassam, Niedoszytko, Marek, Sastre, Joaquin, Martinez‐Infante, E., Kupczyk, Maciej, Torres, María Jose, Matricardi, Paolo Maria, Cecchi, Lorenzo, Celedón, Juan C, Miculinic, Neven, Roche, Nicolas, Migueres, Nicolas, Brussino, Luisa, Florin, Mihaltan, Olze, Heidi, Savouré, Marine, Nekam, Kristof, Pali, Isabella, Okamoto, Yoshitaka, Palomares, O., Lemonnier, Nathanaël, Palosuo, Kati, Soto-Martinez, Manuel, Panaitescu, Carmen, Kvedarienė, Violeta, Panzner, P., Braido, Fulvio, Tsiligianni, Ioanna, Rodriguez-Gonzalez, Monica, Scichilone, Nicola, Canonica, Giogio Walter, Romantowski, Jan, Urrutia-Pereira, Marilyn, Filho, Nelson Augusto Rosario, Ollert, Markus W., Rottem, Menachem, Chkhartishvili, Ekaterine, Sova, Milan, Valovirta, Erkka, Mohammad, Yousser, Sperl, Annette, Spranger, Otto, Neffen, Hugo, Stelmach, Rafael, Burte, Emilie, Valentin Rostan, Marylin, Park, Hae-Sim, Van Ganse, Eric, Van Hage, Marianne, Pitsios, Constantinos, Vasankari, Tuula, and uBibliorum

Subjects
IL-33, Multimorbidity, Asthma, Toll-like receptors, Rhinitis
Abstract

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis.

Published
2023

49. Preliminary Clinical Trial of Biomarkers to Predict Response to Sublingual Immunotherapy for Japanese Cedar Pollinosis

Author

Takahara, Eriko, Matsune, Shoji, Ishida, Mariko, Wakayama, Nozomu, Okubo, Kimihiro, Eriko, Takahara, Shoji, Matsune, Mariko, Ishida, Nozomu, Wakayama, and Kimihiro, Okubo

Subjects
Adult, Male, Vascular Endothelial Growth Factor A, medicine.medical_specialty, Adolescent, Cryptomeria, Administration, Sublingual, Quality of life, Informed consent, Surveys and Questionnaires, Internal medicine, medicine, Humans, Sublingual immunotherapy, Prospective Studies, Prospective cohort study, Aged, business.industry, Therapeutic effect, Rhinitis, Allergic, Seasonal, General Medicine, Middle Aged, Interleukin-12, Slit, Clinical trial, Treatment Outcome, Pollen, Biomarker (medicine), Female, Immunotherapy, business, Biomarkers, Forecasting
Abstract

Background As part of the planning for a future multicenter study, this preliminary clinical trial was performed to explore candidate biomarkers useful for predicting the therapeutic effects of sublingual immunotherapy (SLIT) for Japanese cedar pollinosis (JCP) using serum samples from patients. Methods This prospective study included patients undergoing SLIT for JCP at our hospital. All enrolled patients (n = 17) started SLIT between June and November of 2015. With informed consent from the patients, in January, March, and June of 2016, blood samples were obtained, and an inquiry was conducted using the Japan rhino-conjunctivitis quality of life questionnaire (JRQLQ). Based on the JRQLQ results, we allocated 6 patients with the most favorable results into the high response group (HRG), and 5 patients with the most unfavorable results into the poor response group (PRG). Subsequently, we compared the serum data between the two groups to identify useful biomarkers. Results The IL-12p70 and VEGF levels tended to be higher in the HRG than in the PRG in January, March and June (0.10 > p > 0.05). In addition, the IL-17 level was significantly higher (p Conclusions IL-12p70 and VEGF may be useful biomarkers for predicting the effects of SLIT. In addition, although it does not appear to be useful as a biomarker for evaluating treatment response at the start of SLIT, IL-17 may be useful as a biomarker after the beginning period of SLIT.

Published
2020

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