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12. Finding catatonia requires knowing what to look for

Author

Oldham, Mark A. and Francis, Andrew

Subjects
Medical tests -- Evaluation, Phenotype -- Analysis, Catatonia -- Diagnosis -- Risk factors, Health, Health care industry, Psychology and mental health
Abstract

Catatonia is a psychomotor syndrome identified by its clinical phenotype. Unlike common psychiatric syndromes such as major depression that are characterized by self-report of symptoms, catatonia is identified chiefly by [...]

Published
2023

13. Clinical applicability of Linac-integrated CBCT based NIPAM 3D dosimetry: a dual-institutional investigation.

Author

Kunkyab, Tenzin, Lakrad, Kawtar, Jirasek, Andrew, Oldham, Mark, Quinn, Benjamin, Hyde, Derek, and Adamson, Justus

Subjects
CONE beam computed tomography, MEDICAL dosimetry, LINEAR accelerators, POLYMER colloids, PHARMACEUTICAL gels, DOSIMETERS
Abstract

Objective. To develop and benchmark a novel 3D dose verification technique consisting of polymer gel dosimetry (PGD) with cone-beam-CT (CBCT) readout through a two-institution study. The technique has potential for wide and robust applicability through reliance on CBCT readout. Approach. Three treatment plans (3-field, TG119-C-shape spine, 4-target SRS) were created by two independent institutions (Institutions A and B). A Varian Truebeam linear accelerator was used to deliver the plans to NIPAM polymer gel dosimeters produced at both institutions using an identical approach. For readout, a slow CBCT scan mode was used to acquire pre- and post-irradiation images of the gel (1 mm slice thickness). Independent gel analysis tools were used to process the PGD images (A: VistaAce software, B: in-house MATLAB code). Comparing planned and measured doses, the analysis involved a combination of 1D line profiles, 2D contour plots, and 3D global gamma maps (criteria ranging between 2%1 mm and 5%2 mm, with a 10% dose threshold). Main results. For all gamma criteria tested, the 3D gamma pass rates were all above 90% for 3-field and 88% for the SRS plan. For the C-shape spine plan, we benchmarked our 2% 2 mm result against previously published work using film analysis (93.4%). For 2%2 mm, 99.4% (Institution A data), and 89.7% (Institution B data) were obtained based on VistaAce software analysis, 83.7% (Institution A data), and 82.9% (Institution B data) based on MATLAB. Significance. The benchmark data demonstrate that when two institutions follow the same rigorous procedures gamma passing rates up to 99%, for 2%2 mm criteria can be achieved for substantively different treatment plans. The use of different software and calibration techniques may have contributed to the variation in the 3D gamma results. By sharing the data across institutions, we observe the gamma passing rate is more consistent within each pipeline, indicating the need for standardized analysis methods. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Delirium

Author

Oldham, Mark A., Zimbrean, Paula C., editor, Oldham, Mark A., editor, and Lee, Hochang Benjamin, editor

Published
2019
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21. The Delphi Delirium Management Algorithms: A practical tool for clinicians, the result of a modified Delphi expert consensus approach

Author

AIOS Anesthesiologie, AIOS Psychiatrie, Brain, Ottens, Thomas H, Hermes, Carsten, Page, Valerie, Oldham, Mark, Arora, Rakesh, Bienvenu, O Joseph, van den Boogaard, Mark, Caplan, Gideon, Devlin, John W, Friedrich, Michaela-Elena, van Gool, Willem A, Hanison, James, Hansen, Hans-Christian, Inouye, Sharon K, Kamholz, Barbara, Kotfis, Katarzyna, Maas, Matthew B, MacLullich, Alasdair M J, Marcantonio, Edward R, Morandi, Alessandro, van Munster, Barbara C, Müller-Werdan, Ursula, Negro, Alessandra, Neufeld, Karin J, Nydahl, Peter, Oh, Esther S, Pandharipande, Pratik, Radtke, Finn M, Raedt, Sylvie De, Rosenthal, Lisa J, Sanders, Robert, Spies, Claudia D, Vardy, Emma R L C, Wijdicks, Eelco F, Slooter, Arjen J C, AIOS Anesthesiologie, AIOS Psychiatrie, Brain, Ottens, Thomas H, Hermes, Carsten, Page, Valerie, Oldham, Mark, Arora, Rakesh, Bienvenu, O Joseph, van den Boogaard, Mark, Caplan, Gideon, Devlin, John W, Friedrich, Michaela-Elena, van Gool, Willem A, Hanison, James, Hansen, Hans-Christian, Inouye, Sharon K, Kamholz, Barbara, Kotfis, Katarzyna, Maas, Matthew B, MacLullich, Alasdair M J, Marcantonio, Edward R, Morandi, Alessandro, van Munster, Barbara C, Müller-Werdan, Ursula, Negro, Alessandra, Neufeld, Karin J, Nydahl, Peter, Oh, Esther S, Pandharipande, Pratik, Radtke, Finn M, Raedt, Sylvie De, Rosenthal, Lisa J, Sanders, Robert, Spies, Claudia D, Vardy, Emma R L C, Wijdicks, Eelco F, and Slooter, Arjen J C

Published
2024

22. Advancing specificity in delirium: The delirium subtyping initiative

Author

AIOS Psychiatrie, Brain, Affectieve & Psychotische Med., Bowman, Emily M L, Brummel, Nathan E, Caplan, Gideon A, Cunningham, Colm, Evered, Lis A, Fiest, Kirsten M, Girard, Timothy D, Jackson, Thomas A, LaHue, Sara C, Lindroth, Heidi L, Maclullich, Alasdair M J, McAuley, Daniel F, Oh, Esther S, Oldham, Mark A, Page, Valerie J, Pandharipande, Pratik P, Potter, Kelly M, Sinha, Pratik, Slooter, Arjen J C, Sweeney, Aoife M, Tieges, Zoë, Van Dellen, Edwin, Wilcox, Mary Elizabeth, Zetterberg, Henrik, Cunningham, Emma L, AIOS Psychiatrie, Brain, Affectieve & Psychotische Med., Bowman, Emily M L, Brummel, Nathan E, Caplan, Gideon A, Cunningham, Colm, Evered, Lis A, Fiest, Kirsten M, Girard, Timothy D, Jackson, Thomas A, LaHue, Sara C, Lindroth, Heidi L, Maclullich, Alasdair M J, McAuley, Daniel F, Oh, Esther S, Oldham, Mark A, Page, Valerie J, Pandharipande, Pratik P, Potter, Kelly M, Sinha, Pratik, Slooter, Arjen J C, Sweeney, Aoife M, Tieges, Zoë, Van Dellen, Edwin, Wilcox, Mary Elizabeth, Zetterberg, Henrik, and Cunningham, Emma L

Published
2024

29. Single-fraction Radiation Treatment Dose Response in a Genetically Engineered Mouse Model of Medulloblastoma

Author

Tu, Kevin J., primary, Stewart, Connor E., additional, Williams, Nerissa T., additional, Ma, Yan, additional, Luo, Lixia, additional, Ghosh, Debosir, additional, Weidenhammer, Loren B., additional, Floyd, Scott R., additional, Fan, Yi, additional, Kirsch, David G., additional, Oldham, Mark, additional, and Reitman, Zachary J., additional

Published
2023
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43. What Are Clinicians Missing About Catatonia?

Author

Oldham, Mark A. and Wortzel, Joshua R.

Subjects
Mental illness, Health, Psychology and mental health
Abstract

Catatonia is a psychomotor syndrome that features too little (hypokinetic), too much (hyperkinetic), or abnormal (parakinetic) movement and presents in association with primary mental illness or other medical conditions. (1) [...]

Published
2022

44. Advancing specificity in delirium: The delirium subtyping initiative

Author

Bowman, Emily M. L., primary, Brummel, Nathan E., additional, Caplan, Gideon A., additional, Cunningham, Colm, additional, Evered, Lis A., additional, Fiest, Kirsten M., additional, Girard, Timothy D., additional, Jackson, Thomas A., additional, LaHue, Sara C., additional, Lindroth, Heidi L., additional, Maclullich, Alasdair M. J., additional, McAuley, Daniel F., additional, Oh, Esther S., additional, Oldham, Mark A., additional, Page, Valerie J., additional, Pandharipande, Pratik P., additional, Potter, Kelly M., additional, Sinha, Pratik, additional, Slooter, Arjen J. C., additional, Sweeney, Aoife M., additional, Tieges, Zoë, additional, Van Dellen, Edwin, additional, Wilcox, Mary Elizabeth, additional, Zetterberg, Henrik, additional, and Cunningham, Emma L., additional

Published
2023
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