202 results on '"Oliaro-Bosso, Simonetta"'
Search Results
2. Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer
3. New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold
4. AKR1C3 is a biomarker and druggable target for oropharyngeal tumors
5. AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications.
6. Innovative Methods for the Extraction and Purification of Policosanols from Non-Psychoactive Cannabis Sativa L. And in Vitro Assessment of Their Antioxidant and Anti-Inflammatory Activity
7. Enzymatic and Chemical In Vitro Reconstitution of Iron-Sulfur Cluster Proteins
8. Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis
9. Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid
10. Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach
11. Recent Cannabinoid Delivery Systems
12. Thermoresponsive mesoporous silica nanoparticles as a carrier for skin delivery of quercetin
13. Mesoporous silica as topical nanocarriers for quercetin: characterization and in vitro studies
14. Extraction and Characterization of Bromelain from Pineapple Core: A Strategy for Pineapple Waste Valorization
15. HYDROXYLATED HETEROCYCLES AS BIOISOSTERES OF THE CARBOXYLIC FUNCTION: DESIGN OF NEW AKR1C3 INHIBITORS ACTIVE IN PROSTATE CANCER
16. 4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase
17. Nanomaterial–protein interactions: the case of pristine and functionalized carbon nanotubes and porcine gastric mucin
18. Mesoporous silica nanoparticles as a promising skin delivery system for methotrexate
19. Towards a metabolomic approach to investigate iron–sulfur cluster biogenesis
20. Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme
21. Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping
22. Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs)
23. Regulation of HMGCoA Reductase Activity by Policosanol and Octacosadienol, a New Synthetic Analogue of Octacosanol
24. A New Bevacizumab Carrier for Intravitreal Administration: Focus on Stability
25. Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae
26. Assessment of In-Situ Gelling Microemulsion Systems upon Temperature and Dilution Condition for Corneal Delivery of Bevacizumab
27. Umbelliferone aminoalkyl derivatives as inhibitors of oxidosqualene cyclases from Saccharomyces cerevisiae, Tripanosoma cruzi, and Pneumocystis carinii
28. AKR1C3 is a biomarker and druggable target for oropharyngeal tumors
29. Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors
30. Application of an in house bioisosteric approach to the design of innovative inhibitors of aldo-keto reductase 1C3 (AKR1C3)
31. Thermosensitive Nanocomposite Hydrogels for Intravitreal Delivery of Cefuroxime
32. Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae
33. Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3
34. Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo–keto reductase 1C3 target affinity
35. Arylpiperidines as a new class of oxidosqualene cyclase inhibitors
36. Cannabinoid Delivery Systems for Pain and Inflammation Treatment
37. Indoor illumination: A possible pitfall in toxicological assessment of photo-active nanomaterials
38. Androgen-AR axis in primary and metastatic prostate cancer: chasing steroidogenic enzymes for therapeutic intervention
39. Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors
40. Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells.
41. A mutation in yeast oxidosqualene cyclase (Erg7) makes it independent of 3-ketoreductase activity (Erg27)
42. Surface modified TiO2 nanopowders for sunscreen applications
43. Functional characterization by site-directed mutagenesis of human oxidosqualene cyclase (OSC) expressed in Pichia pastoris
44. Characterization of C-4 demethylation complex of cholesterol biosynthesis
45. Tailored preparation of modified TiO2 nanopowders for the study of the role of photo-reactivity in the toxicity toward keratinocytes
46. Different interaction between oxidosqualene cyclase and steroid-3-ketoreductase from yeasts to mammals
47. The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination
48. Divergent interactions involving the oxidosqualene cyclase and thesteroid-3-ketoreductase in the sterol biosynthetic pathway ofmammals and yeasts
49. Different Interaction between Oxidosqualene Cyclase and Steroid-3-ketoreductase in Yeast and Mammals
50. Access of the substrate to the active site of yeast oxidosqualene cyclase: a modelling and site-directed mutagenesis approach
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