110 results on '"Ombeva A"'
Search Results
2. Management of Multisystem Inflammatory Syndrome in Children (MIS-C) in resource limited settings: The Kenyan Experience
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Angela Migowa, Pauline Samia, Sean del Rossi, Oliver Ombeva Malande, Jasmit Shah, Chemutai Kenei, Joy Ayaya, Daisy Jeruto, Laura Oyiengo, and Laura Lewandowski
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Pediatrics ,RJ1-570 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Since the onset of the recent COVID-19 pandemic, there have been growing concerns regarding multisystem inflammatory syndrome in children (MIS-C). This study aims to describe the clinico-epidemiological profile and challenges in management of MIS-C in low-middle income countries by highlighting the Kenyan experience. Methods A retrospective study at the Aga Khan University Hospital Nairobi, Avenue Hospital Kisumu and Kapsabet County Referral Hospital was undertaken to identify cases of MIS-C. A detailed chart review using the World Health Organization (WHO) data collection tool was adapted to incorporate information on socio-demographic details and treatment regimens. Findings Twenty children with MIS-C were identified across the three facilities between August 1st 2020 and August 31st 2021. Seventy percent of the children were male (14 of 20). COVID-19 PCR testing was done for five children and only one was positive. The commonest clinical symptoms were fever (90%), tachycardia (80%), prolonged capillary refill (80%), oral mucosal changes (65%) and peripheral cutaneous inflammation (50%). Four children required admission into the critical care unit for ventilation support and inotropic support. Cardiac evaluation was available for six patients four of whom had myocardial dysfunction, three had valvulitis and one had pericarditis. Immunoglobulin therapy was availed to two children and systemic steroids provided for three children. There were no documented mortalities. Interpretation We describe the first case series of MIS-C in East and Central Africa. Majority of suspected cases of MIS-C did not have access to timely COVID-19 testing and other appropriate evaluations which highlights the iniquity in access to diagnostics and treatment.
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- 2022
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3. Management of Multisystem Inflammatory Syndrome in Children (MIS-C) in resource limited settings: The Kenyan Experience
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Migowa, Angela, Samia, Pauline, del Rossi, Sean, Malande, Oliver Ombeva, Shah, Jasmit, Kenei, Chemutai, Ayaya, Joy, Jeruto, Daisy, Oyiengo, Laura, and Lewandowski, Laura
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- 2022
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4. Malaria and dengue fever in febrile children entering healthcare facilities in Mwanza, Tanzania.
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Kayange, Neema M., Malande, Oliver Ombeva, Koliopoulos, Philip, Gehring, Stephan, Groendahl, Britta, Wajanga, Bahati, Msaki, Bahati, Revocatus, Baraka, and Mshana, Stephen E.
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RAPID diagnostic tests , *DENGUE , *HEALTH facilities , *DENGUE viruses , *LOW-income countries - Abstract
Plasmodium spp. infections and cases of malaria are a long-standing public health problem for children living in middle- and low-income countries. Dengue virus causes an emerging under-recognized disease burden. A cross sectional study was conducted between March 2020 and December 2021 to determine the status of malaria and dengue fever, and the associated factors in children living in Mwanza, Tanzania. Clinical features were recorded; blood samples were analyzed using dengue NS1 rapid diagnostics test (NS1-RDT), malaria rapid diagnostic test (MRDT) and PCR and microscopy for malaria parasites. Descriptive analysis was based on infection status; odds ratio and confidence interval were used to determine the factors associated with dengue fever and malaria. The prevalence of malaria in the 436 children included in the final analysis was 15.6%, 8.5%, and 12.1% as determined by MRDT, blood smear examination and PCR, respectively. The prevalence of dengue fever determined by the NS1-RDT was 7.8%. Body rash, muscle and joint/bone pain were associated with a positive rapid dengue test result. Retro-orbital pain characterized Plasmodium spp. and dengue virus co-infections. Clinical signs and symptoms could not readily differentiate between malaria and dengue fever patients or patients co-infected with both causative agents underscoring the urgent need for the accurate laboratory diagnostics. Additional large-scale studies are required to assess the epidemiological burden of acute febrile illness in developing countries and to produce data that will guide empirical treatment. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Seroprevalence of Dengue and Chikungunya Virus Infections in Children Living in Sub-Saharan Africa: Systematic Review and Meta-Analysis
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Neema Kayange, Duncan K Hau, Kevin Pain, Stephen E Mshana, Robert Peck, Stephan Gehring, Britta Groendahl, Philip Koliopoulos, Baraka Revocatus, Evarist B Msaki, and Ombeva Malande
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prevalence ,dengue virus ,chikungunya virus ,Sub-Saharan Africa ,systematic review ,Pediatrics ,RJ1-570 - Abstract
Dengue and chikungunya viruses are frequent causes of malarial-like febrile illness in children. The rapid increase in virus transmission by mosquitoes is a global health concern. This is the first systematic review and meta-analysis of the childhood prevalence of dengue and chikungunya in Sub-Saharan Africa (SSA). A comprehensive search of the MEDLINE (Ovid), Embase (Ovid), and Cochrane Library (Wiley) databases was conducted on 28 June 2019, and updated on 12 February 2022. The search strategy was designed to retrieve all articles pertaining to arboviruses in SSA children using both controlled vocabulary and keywords. The pooled (weighted) proportion of dengue and chikungunya was estimated using a random effect model. The overall pooled prevalence of dengue and chikungunya in SSA children was estimated to be 16% and 7%, respectively. Prevalence was slightly lower during the period 2010–2020 compared to 2000–2009. The study design varied depending on the healthcare facility reporting the disease outbreak. Importantly, laboratory methods used to detect arbovirus infections differed. The present review documents the prevalence of dengue and chikungunya in pediatric patients throughout SSA. The results provide unprecedented insight into the transmission of dengue and chikungunya viruses among these children and highlight the need for enhanced surveillance and controlled methodology.
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- 2023
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6. Predictors of Tetanus Vaccine Uptake among Pregnant Women in Khartoum State, Sudan: A Hospital-Based Cross-Sectional Study
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Zienab A. Ibrahim, Majdi M. Sabahelzain, Yasir Ahmed Mohammed Elhadi, Ombeva Oliver Malande, and Suad Babiker
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tetanus toxoid vaccine ,vaccine uptake ,tetanus ,pregnant women ,Sudan ,Medicine - Abstract
Tetanus toxoid (TT) vaccination during pregnancy has been proven as an effective preventative measure to reduce the incidence of maternal and neonatal morbidity and mortality worldwide. This study aimed to assess the determinants of TT vaccine uptake among pregnant women at two public maternity specialized hospitals in Sudan. A hospital-based cross-sectional study was conducted at two public hospitals, Omdurman Maternity Hospital and Al Saudi Hospital in Omdurman, Khartoum State, in Sudan from February to April 2020. Logistic regression analysis was carried out to identify factors associated with receiving three or more doses of the TT vaccine among pregnant women, presented as odds ratios, with p-values < 0.05 considered significant (at a 95% confidence interval). The study recruited 350 pregnant women, with 313 participants included in the analysis. This study found that only 40% of the pregnant women had received three doses or more of the TT vaccine. Pregnant women who attended Al Saudi Hospital were less likely to be vaccinated with the recommended dose of the TT vaccine in districts at high risk (received ≥3 doses) compared to those who attended Omdurman Hospital [OR = 0.49 (95% C.I. 0.29–0.82), p-value < 0.05]. Furthermore, the number of children at home was a significant predictor of the mothers’ immunization status as those with five children or more were ten times more likely to be vaccinated with three doses or more [OR = 10.54 (95% C.I. 4.30–25.86), p-value < 0.05]. We conclude that this low rate of TT vaccine uptake found in this study among pregnant women increases the number of newborn babies susceptible to contracting neonatal tetanus. The findings of this study should be considered in the development of communication strategies targeting and prioritizing at-risk groups to increase TT vaccine uptake among pregnant women in Sudan.
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- 2023
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7. Strengthening capacity in hospitals to reduce perinatal morbidity and mortality through a codesigned intervention package: protocol for a realist evaluation as part of a stepped-wedge trial of the Action Leveraging Evidence to Reduce perinatal morTality and morbidity (ALERT) in sub-Saharan Africa project
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Lenka Benova, Peter Waiswa, Claudia Hanson, Bruno Marchal, Ibukun-Oluwa Omolade Abejirinde, Thérèse Delvaux, Kefilath Bello, Jean-Paul Dossou, Nicola Orsini, Helle Mølsted Alvesson, Effie Chipeta, William Stones, Helga Naburi, Joanne Welsh, Hashim Hounkpatin, Wim Van Damme, Mechthild Gross, Samuel Meja, Kristi Sidney, Armelle Vigan, Virginia Castellano Pleguezuelo, Christelle Boyi Metogni, D A Mkoka, Gertrude Namazzi, Ahossi Angèle Florence Laure, Andrea B. Pembe, Ann-Beth Nygaard Moller, Antoinette Sognonvi, Banougnin Bolade Hamed, Beatrice Mwilike, Bianca Kandeya, Dickson Mkoka, Elizabeth Ombeva Ayebare, Fadhlun M Alwy Al-Beity, Gisele Houngbo, Gottfried Agballa, Hussein L. Kidanto, Joseph Akuze, Josephine Babirye, Kristi Sidney Annerstedt, Lilian Mselle, Muzdalifat Abeid, Philip Wanduru, Razak Mussa, Regine Unkels, Rian Snijders, Schadrac Agbla, Tumbwene Mwansisya, Yesaya Z. Nyirenda, and Zamoyoni Julius
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Medicine - Abstract
Introduction Despite a strong evidence base for developing interventions to reduce child mortality and morbidity related to pregnancy and delivery, major knowledge–implementation gaps remain. The Action Leveraging Evidence to Reduce perinatal morTality and morbidity (ALERT) in sub-Saharan Africa project aims to overcome these gaps through strengthening the capacity of multidisciplinary teams that provide maternity care. The intervention includes competency-based midwife training, community engagement for study design, mentoring and quality improvement cycles. The realist process evaluation of ALERT aims at identifying and testing the causal pathway through which the intervention achieves its impact.Methods and analysis This realist process evaluation complements the effectiveness evaluation and the economic evaluation of the ALERT intervention. Following the realist evaluation cycle, we will first elicit the initial programme theory on the basis of the ALERT theory of change, a review of the evidence on adoption and diffusion of innovations and the perspectives of the stakeholders. Second, we will use a multiple embedded case study design to empirically test the initial programme theory in two hospitals in each of the four intervention countries. Qualitative and quantitative data will be collected, using in-depth interviews with hospital staff and mothers, observations, patient exit interviews and (hospital) document reviews. Analysis will be guided by the Intervention-Actors-Context-Mechanism-Outcome configuration heuristic. We will use thematic coding to analyse the qualitative data. The quantitative data will be analysed descriptively and integrated in the analysis using a retroductive approach. Each case study will end with a refined programme theory (in-case analysis). Third, we will carry out a cross-case comparison within and between the four countries. Comparison between study countries should enable identifying relevant context factors that influence effectiveness and implementation, leading to a mid-range theory that may inform the scaling up the intervention.Ethics and dissemination In developing this protocol, we paid specific attention to cultural sensitivity, the do no harm principle, confidentiality and non-attribution. We received ethical approval from the local and national institutional review boards in Tanzania, Uganda, Malawi, Benin, Sweden and Belgium. Written or verbal consent of respondents will be secured after explaining the purpose, potential benefits and potential harms of the study using an information sheet. The results will be disseminated through workshops with the hospital staff and national policymakers, and scientific publications and conferences.Trial registration number PACTR202006793783148.
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- 2022
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8. PA-364 Knowledge and reporting of adverse events following childhood immunization among health workers and caregivers at Mengo hospital, Kampala
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Watyaba, Benjamin, primary, Knezevic, Ivana, additional, Adong, Florence, additional, Kewaza, Faith, additional, Bazira, Henry, additional, Nankonyoli, Oliver, additional, Malande, Ombeva, additional, and Kikaire, Bernard, additional
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- 2023
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9. Encouraging improvement in HPV vaccination coverage among adolescent girls in Kampala, Uganda.
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Lydia Patrick, Sabrina Bakeera-Kitaka, Joseph Rujumba, and Oliver Ombeva Malande
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Medicine ,Science - Abstract
IntroductionWHO recommends vaccination against HPV for girls before sexual debut. Uganda started HPV vaccination in 2008 as pilot programs in 2 districts, followed by national roll out in 2015. Despite the availability of vaccines against human papillomavirus (HPV) in Uganda in the period covered by the study, there was reported low HPV vaccine uptake and completion especially of the second dose in Uganda; with little information available on timely completion of HPV vaccine and the associated factors in Uganda. This study was therefore done to determine the HPV vaccine dose 2 completion and describe the possible factors associated with timely HPV vaccine completion and non-completion among girls of age 9-14 years attending the adolescent clinic at Mulago hospital.MethodsA retrospective mixed methods study was conducted in Mulago National Referral hospital adolescent clinic. Data were mainly collected through review of charts and folders for clinic attendance by eligible girls and focus group discussions with eligible girls that completed the 2 doses of HPV vaccine on recommended/scheduled time.ResultsOut of the 201 girls studied, 87 girls (43.3%) had timely completion of the HPV vaccination. Knowledge about HPV infection and HPV vaccine benefits, positive peer influence and healthcare worker recommendation to get vaccinated at health facility level positively influenced timely completion of HPV vaccine. Among barriers to completion of HPV vaccine identified were: inadequate information about HPV infection and HPV vaccine, concerns about HPV vaccine efficacy and safety, unclear communication with adolescents/caregivers from healthcare workers and -stock out of the HPV vaccine.ConclusionTimely completion of the second dose of HPV vaccine among girls attending the adolescent clinic of Mulago hospital was low (at 43.3%) but higher when compared to earlier published reports. Interventions around improved social mobilization, enhanced outreach and static vaccination approach and education of eligible girls on HPV vaccination can help increase vaccine uptake.
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- 2022
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10. The Current Situation Regarding Long-Acting Insulin Analogues Including Biosimilars Among African, Asian, European, and South American Countries; Findings and Implications for the Future
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Brian Godman, Mainul Haque, Trudy Leong, Eleonora Allocati, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Carlos Vassalo, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M. Muksudul Alam, Iffat Jahan, Zubair Mahmood Kamal, Humaira Hasin, Munzur-E-Murshid, Shamsun Nahar, Monami Haque, Siddhartha Dutta, Jha Pallavi Abhayanand, Rimple Jeet Kaur, Godfrey Mutashambara Rwegerera, Renata Cristina Rezende Macedo do Nascimento, Isabella Piassi Dias Godói, Mohammed Irfan, Adefolarin A. Amu, Patrick Matowa, Joseph Acolatse, Robert Incoom, Israel Abebrese Sefah, Jitendra Acharya, Sylvia Opanga, Lisper Wangeci Njeri, David Kimonge, Hye-Young Kwon, SeungJin Bae, Karen Koh Pek Khuan, Abdullahi Rabiu Abubakar, Ibrahim Haruna Sani, Tanveer Ahmed Khan, Shahzad Hussain, Zikria Saleem, Oliver Ombeva Malande, Thereza Piloya-Were, Rosana Gambogi, Carla Hernandez Ortiz, Luke Alutuli, Aubrey Chichonyi Kalungia, Iris Hoxha, Vanda Marković-Peković, Biljana Tubic, Guenka Petrova, Konstantin Tachkov, Ott Laius, András Harsanyi, András Inotai, Arianit Jakupi, Svens Henkuzens, Kristina Garuoliene, Jolanta Gulbinovič, Magdalene Wladysiuk, Jakub Rutkowski, Ileana Mardare, Jurij Fürst, Stuart McTaggart, Sean MacBride-Stewart, Caridad Pontes, Corinne Zara, Eunice Twumwaa Tagoe, Rita Banzi, Janney Wale, and Mihajlo Jakovljevic
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Africa ,biosimilars ,cross-national study ,drug utilisation ,Europe ,health policy ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Diabetes mellitus rates continue to rise, which coupled with increasing costs of associated complications has appreciably increased global expenditure in recent years. The risk of complications are enhanced by poor glycaemic control including hypoglycaemia. Long-acting insulin analogues were developed to reduce hypoglycaemia and improve adherence. Their considerably higher costs though have impacted their funding and use. Biosimilars can help reduce medicine costs. However, their introduction has been affected by a number of factors. These include the originator company dropping its price as well as promoting patented higher strength 300 IU/ml insulin glargine. There can also be concerns with different devices between the manufacturers.Objective: To assess current utilisation rates for insulins, especially long-acting insulin analogues, and the rationale for patterns seen, across multiple countries to inform strategies to enhance future utilisation of long-acting insulin analogue biosimilars to benefit all key stakeholders.Our approach: Multiple approaches including assessing the utilisation, expenditure and prices of insulins, including biosimilar insulin glargine, across multiple continents and countries.Results: There was considerable variation in the use of long-acting insulin analogues as a percentage of all insulins prescribed and dispensed across countries and continents. This ranged from limited use of long-acting insulin analogues among African countries compared to routine funding and use across Europe in view of their perceived benefits. Increasing use was also seen among Asian countries including Bangladesh and India for similar reasons. However, concerns with costs and value limited their use across Africa, Brazil and Pakistan. There was though limited use of biosimilar insulin glargine 100 IU/ml compared with other recent biosimilars especially among European countries and Korea. This was principally driven by small price differences in reality between the originator and biosimilars coupled with increasing use of the patented 300 IU/ml formulation. A number of activities were identified to enhance future biosimilar use. These included only reimbursing biosimilar long-acting insulin analogues, introducing prescribing targets and increasing competition among manufacturers including stimulating local production.Conclusions: There are concerns with the availability and use of insulin glargine biosimilars despite lower costs. This can be addressed by multiple activities.
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- 2021
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11. Seroprevalence of Dengue and Chikungunya Virus Infections in Children Living in Sub-Saharan Africa: Systematic Review and Meta-Analysis
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Kayange, Neema, primary, Hau, Duncan K, additional, Pain, Kevin, additional, Mshana, Stephen E, additional, Peck, Robert, additional, Gehring, Stephan, additional, Groendahl, Britta, additional, Koliopoulos, Philip, additional, Revocatus, Baraka, additional, Msaki, Evarist B, additional, and Malande, Ombeva, additional
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- 2023
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12. Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future
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Olayinka O. Ogunleye, Debashis Basu, Debjani Mueller, Jacqueline Sneddon, R. Andrew Seaton, Adesola F. Yinka-Ogunleye, Joshua Wamboga, Nenad Miljković, Julius C. Mwita, Godfrey Mutashambara Rwegerera, Amos Massele, Okwen Patrick, Loveline Lum Niba, Melaine Nsaikila, Wafaa M. Rashed, Mohamed Ali Hussein, Rehab Hegazy, Adefolarin A. Amu, Baffour Boaten Boahen-Boaten, Zinhle Matsebula, Prudence Gwebu, Bongani Chirigo, Nongabisa Mkhabela, Tenelisiwe Dlamini, Siphiwe Sithole, Sandile Malaza, Sikhumbuzo Dlamini, Daniel Afriyie, George Awuku Asare, Seth Kwabena Amponsah, Israel Sefah, Margaret Oluka, Anastasia N. Guantai, Sylvia A. Opanga, Tebello Violet Sarele, Refeletse Keabetsoe Mafisa, Ibrahim Chikowe, Felix Khuluza, Dan Kibuule, Francis Kalemeera, Mwangana Mubita, Joseph Fadare, Laurien Sibomana, Gwendoline Malegwale Ramokgopa, Carmen Whyte, Tshegofatso Maimela, Johannes Hugo, Johanna C. Meyer, Natalie Schellack, Enos M. Rampamba, Adel Visser, Abubakr Alfadl, Elfatih M. Malik, Oliver Ombeva Malande, Aubrey C. Kalungia, Chiluba Mwila, Trust Zaranyika, Blessmore Vimbai Chaibva, Ioana D. Olaru, Nyasha Masuka, Janney Wale, Lenias Hwenda, Regina Kamoga, Ruaraidh Hill, Corrado Barbui, Tomasz Bochenek, Amanj Kurdi, Stephen Campbell, Antony P. Martin, Thuy Nguyen Thi Phuong, Binh Nguyen Thanh, and Brian Godman
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COVID-19 ,Africa ,prevalence ,treatment ,misinformation ,health policy ,Therapeutics. Pharmacology ,RM1-950 - Abstract
BackgroundThe COVID-19 pandemic has already claimed considerable lives. There are major concerns in Africa due to existing high prevalence rates for both infectious and non-infectious diseases and limited resources in terms of personnel, beds and equipment. Alongside this, concerns that lockdown and other measures will have on prevention and management of other infectious diseases and non-communicable diseases (NCDs). NCDs are an increasing issue with rising morbidity and mortality rates. The World Health Organization (WHO) warns that a lack of nets and treatment could result in up to 18 million additional cases of malaria and up to 30,000 additional deaths in sub-Saharan Africa.ObjectiveDocument current prevalence and mortality rates from COVID-19 alongside economic and other measures to reduce its spread and impact across Africa. In addition, suggested ways forward among all key stakeholder groups.Our ApproachContextualise the findings from a wide range of publications including internet-based publications coupled with input from senior-level personnel.Ongoing ActivitiesPrevalence and mortality rates are currently lower in Africa than among several Western countries and the USA. This could be due to a number of factors including early instigation of lockdown and border closures, the younger age of the population, lack of robust reporting systems and as yet unidentified genetic and other factors. Innovation is accelerating to address concerns with available equipment. There are ongoing steps to address the level of misinformation and its consequences including fines. There are also ongoing initiatives across Africa to start addressing the unintended consequences of COVID-19 activities including lockdown measures and their impact on NCDs including the likely rise in mental health disorders, exacerbated by increasing stigma associated with COVID-19. Strategies include extending prescription lengths, telemedicine and encouraging vaccination. However, these need to be accelerated to prevent increased morbidity and mortality.ConclusionThere are multiple activities across Africa to reduce the spread of COVID-19 and address misinformation, which can have catastrophic consequences, assisted by the WHO and others, which appear to be working in a number of countries. Research is ongoing to clarify the unintended consequences given ongoing concerns to guide future activities. Countries are learning from each other.
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- 2020
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13. Challenges and Innovations Brought about by the COVID-19 Pandemic Regarding Medical and Pharmacy Education Especially in Africa and Implications for the Future
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Ayukafangha Etando, Adefolarin A. Amu, Mainul Haque, Natalie Schellack, Amanj Kurdi, Alian A. Alrasheedy, Angela Timoney, Julius C. Mwita, Godfrey Mutashambara Rwegerera, Okwen Patrick, Loveline Lum Niba, Baffour Boaten Boahen-Boaten, Felicity Besong Tabi, Olufunke Y. Amu, Joseph Acolatse, Robert Incoom, Israel Abebrese Sefah, Anastasia Nkatha Guantai, Sylvia Opanga, Ibrahim Chikowe, Felix Khuluza, Dan Kibuule, Francis Kalemeera, Ester Hango, Jennie Lates, Joseph Fadare, Olayinka O. Ogunleye, Zikria Saleem, Frasia Oosthuizen, Werner Cordier, Moliehi Matlala, Johanna C. Meyer, Gustav Schellack, Amos Massele, Oliver Ombeva Malande, Aubrey Chichonyi Kalungia, James Sichone, Sekelani S. Banda, Trust Zaranyika, Stephen Campbell, and Brian Godman
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Africa ,COVID-19 ,cross country learning ,e-learning ,hybrid approaches ,Internet platforms ,Medicine - Abstract
Background: Multiple measures introduced early to restrict COVID-19 have dramatically impacted the teaching of medical and pharmacy students, exacerbated by the lack of infrastructure and experience with e-learning at the start of the pandemic. In addition, the costs and reliability of the Internet across Africa pose challenges alongside undertaking clinical teaching and practical programmes. Consequently, there is a need to understand the many challenges and how these were addressed, given increasingly complex patients, to provide future direction. Method: An exploratory study was conducted among senior-level medical and pharmacy educators across Africa, addressing four key questions, including the challenges resulting from the pandemic and how these were dealt with. Results: Staff and student members faced multiple challenges initially, including adapting to online learning. In addition, concerns with the lack of equipment (especially among disadvantaged students), the costs of Internet bundles, and how to conduct practicals and clinical teaching. Multiple activities were undertaken to address these challenges. These included training sessions, developing innovative approaches to teaching, and seeking ways to reduce Internet costs. Robust approaches to practicals, clinical teaching, and assessments have been developed. Conclusions: Appreciable difficulties to teaching arising from the pandemic are being addressed across Africa. Research is ongoing to improve education and assessments.
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- 2021
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14. Predictors of Tetanus Vaccine Uptake among Pregnant Women in Khartoum State, Sudan: A Hospital-Based Cross-Sectional Study
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Ibrahim, Zienab A., primary, Sabahelzain, Majdi M., additional, Elhadi, Yasir Ahmed Mohammed, additional, Malande, Ombeva Oliver, additional, and Babiker, Suad, additional
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- 2023
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15. The immediate treatment outcomes and cost estimate for managing clinical measles in children admitted at Mulago Hospital: A retrospective cohort study
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Namugga, Barbara, primary, Malande, Ombeva, additional, Kitonsa, Jonathan, additional, Manirakiza, Leonard, additional, Banura, Cecily, additional, and Mupere, Ezekiel, additional
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- 2023
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16. Strategies to Improve Antimicrobial Utilization with a Special Focus on Developing Countries
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Brian Godman, Abiodun Egwuenu, Mainul Haque, Oliver Ombeva Malande, Natalie Schellack, Santosh Kumar, Zikria Saleem, Jacqueline Sneddon, Iris Hoxha, Salequl Islam, Julius Mwita, Renata Cristina Rezende Macedo do Nascimento, Isabella Piassi Dias Godói, Loveline Lum Niba, Adefolarin A. Amu, Joseph Acolatse, Robert Incoom, Israel Abebrese Sefah, Sylvia Opanga, Amanj Kurdi, Ibrahim Chikowe, Felix Khuluza, Dan Kibuule, Olayinka O. Ogunleye, Adesola Olalekan, Vanda Markovic-Pekovic, Johanna C. Meyer, Abubakr Alfadl, Thuy Nguyen Thi Phuong, Aubrey C. Kalungia, Stephen Campbell, Alice Pisana, Janney Wale, and R. Andrew Seaton
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antimicrobials ,antimicrobial stewardship programs ,antimicrobial resistance ,healthcare-associated infections ,COVID-19 ,lower- and middle-income countries ,Science - Abstract
Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity, mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, nationally and regionally to enhance appropriate antibiotic utilization across sectors to reduce AMR, with the overuse of antibiotics exacerbated by the COVID-19 pandemic. Effectively tackling AMR is crucial for all countries. Principally a narrative review of ongoing activities across sectors was undertaken to improve antimicrobial use and address issues with vaccines including COVID-19. Point prevalence surveys have been successful in hospitals to identify areas for quality improvement programs, principally centering on antimicrobial stewardship programs. These include reducing prolonged antibiotic use to prevent surgical site infections. Multiple activities centering on education have been successful in reducing inappropriate prescribing and dispensing of antimicrobials in ambulatory care for essentially viral infections such as acute respiratory infections. It is imperative to develop new quality indicators for ambulatory care given current concerns, and instigate programs with clear public health messaging to reduce misinformation, essential for pandemics. Regular access to effective treatments is needed to reduce resistance to treatments for HIV, malaria and tuberculosis. Key stakeholder groups can instigate multiple initiatives to reduce AMR. These need to be followed up.
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- 2021
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17. Predictors of Tetanus Vaccine Uptake among Pregnant Women in Sudan: A Hospital-Based Cross-Sectional Study
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Ibrahim, Zienab A, primary, Sabahelzain, Majdi, additional, Elhadi, Yasir Ahmed Mohammed, additional, Oliver, Ombeva, additional, and Babiker, Suad, additional
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- 2023
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18. A ten-year review of ESBL and non-ESBL Escherichia coli bloodstream infections among children at a tertiary referral hospital in South Africa.
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Oliver Ombeva Malande, James Nuttall, Vashini Pillay, Colleen Bamford, and Brian Eley
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Medicine ,Science - Abstract
INTRODUCTION:There are few studies describing Escherichia coli (E. coli) bloodstream infection (BSI) among children in Africa, yet E.coli is increasing in importance as a cause of antibiotic resistant infection in paediatric settings. METHODS:In this retrospective, descriptive study aspects of E. coli BSI epidemiology are described over a 10-year period including incidence risk, risk factors for extended-spectrum β-lactamase (ESBL)-producing E. coli BSI, antibiotic susceptibility of the bacterial isolates and outcome including risk factors for severe disease. RESULTS:There were 583 new E. coli BSI episodes among 217,483 admissions, an overall incidence risk of 2.7 events/1,000 hospital admissions. Of 455 of these E. coli BSI episodes that were analysed, 136 (29.9%) were caused by ESBL-producing isolates. Risk factors for ESBL-producing E. coli BSI included hospitalization in the 28-day period preceding E. coli BSI episodes, having an underlying chronic illness other than HIV infection at the time of the E. coli BSI and having a temperature of 38° Celsius or higher at the time of the E. coli BSI. None of the E. coli isolates were resistant to carbapenems or colistin. The mortality rate was 5.9% and admission to the intensive care unit was required in 12.3% of BSI episodes. Predictors of severe disease included age less than 1 month, hospitalization in the 28-day period preceding E. coli BSI and BSI without a definable focus. CONCLUSIONS:These findings extend our understanding of E. coli BSI in a sub-Saharan African setting, provide useful information that can guide empiric treatment choices for community- and hospital-acquired BSI and help inform prevention strategies.
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- 2019
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19. Barriers to effective uptake and provision of immunization in a rural district in Uganda.
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Oliver Ombeva Malande, Deogratias Munube, Rachel Nakatugga Afaayo, Kisakye Annet, Bongomin Bodo, Andrew Bakainaga, Elizabeth Ayebare, Sam Njunwamukama, Edison Arwanire Mworozi, and Andrew Munyalo Musyoki
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Medicine ,Science - Abstract
IntroductionHoima, one of the largest districts in mid- western Uganda, has persistently performed poorly with low immunization coverage, high immunization drop outs rates and repeated outbreaks of vaccine preventable diseases especially measles. The objectives of this study were to evaluate the state of immunization services and to identify the gaps in immunization health systems that contribute to low uptake and completion of immunization schedules in Hoima District.MethodsThis was a cross sectional mixed methods study, utilizing both qualitative and quantitative approaches. A situation analysis of the immunization services was carried out using in-depth interviews with vaccinators, focus group discussions and key informant interviews with ethno-videography. Secondary data was sourced from records at headquarters and vaccination centres within Hoima District. The quantitative component utilized cluster random sampling with sample size estimated using the World Health Organization's 30 cluster sampling technique.ResultsA total of 311 caretaker/child pairs were included in the study. Immunization completion among children of age at least 12 months was 95% for BCG, 96% for OPV0, 93% for DPT1, 84.5% for DPT2, 81% for DPT3 and 65.5% for measles vaccines. Access to immunization centres is difficult due to poor road terrain, which affects effectiveness of outreach program, support supervision, mentorship and timely delivery of immunization program support supplies especially refrigerator gas and vaccines. Some facilities are under-equipped to effectively support the program. Adverse Events Following Immunization (AEFI) identification, reporting and management is poorly understood.ConclusionImmunization services in Hoima District require urgent improvement in the following areas: vaccine supply, expanding service delivery points, more health workers, transport and tailored mechanisms to ensure adequate communication between health workers and caretakers.
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- 2019
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20. Predictors of Tetanus Vaccine Uptake among Pregnant Women in Sudan: A Hospital-Based Cross-Sectional Study
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Zienab A Ibrahim, Majdi Sabahelzain, Yasir Ahmed Mohammed Elhadi, Ombeva Oliver, and Suad Babiker
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obstetrics_gynaecology - Abstract
Tetanus toxoid (TT) vaccination during pregnancy has been proven as an effective preven-tive measure to reduce the incidence of maternal and neonatal morbidity and mortality worldwide. This study aimed to assess the determinants of TT vaccine uptake among pregnant women in two public maternity specialized hospitals in Sudan. A hospi-tal-based cross-sectional study was conducted in two public hospitals, Omdurman Ma-ternity and AL-Saudi hospitals in Omdurman, Khartoum State in Sudan, from February to April 2020. Logistic regression analysis was carried out to identify factors associated with receiving three or more doses of TT vaccine among pregnant women (protected against tetanus), presented as Odds ratios, with p-values
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- 2023
21. The immediate treatment outcomes and cost estimate for managing clinical measles in children admitted at Mulago Hospital: a retrospective cohort study
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Barbara Namugga, Ombeva Malande, Jonathan Kitonsa, Cecily Banura, and Ezekiel Mupere
- Abstract
BackgroundOver the recent years, the Ministry of Health in Uganda has reported multiple measles outbreaks in various districts despite the availability of a safe cost effective vaccine. Measles, especially among the unvaccinated, can lead to serious complications including death, while its management heavily burdens the family and health care delivery system. Whereas the cost of measles vaccination is known, the cost of treating measles is unknown. Knowledge of this can inform policy and planning for healthcare services.MethodA retrospective single cohort study using records review was conducted to determine the immediate treatment outcomes and estimate the health care delivery cost of managing measles among children 0-12 years admitted at Mulago hospital throughout 2018. Demographics, complications, vaccination status, discharge status, duration of hospital stay, type of treatment, supplies used and investigations done were abstracted from the patient charts. The costs of treatment were obtained from the hospital pharmacy price list while the unit cost of utilities, human resource, food and security were obtained from the hospital accounts department. Patients’ characteristics were summarized descriptively. For all cost information, we reported the mean with standard deviation (SD) and range, and costs information was stratified and presented as direct health care (blood test, radiology and treatment) and direct non health care.ResultsOut of 536 patient charts, 267 were chosen, 51% were for females and the median age was 1.0 (IQR 0.75-2) years. Sixty-three patients (24%) were immunised, 79 (29%) were not immunized, 56 (21%) were not due for immunisation at the time of hospitalisation while the status of 69 (26%) was not recorded. Median length of hospital stay was 4.0 days (IQR 3.0-7.0) with majority (n=207, 77%) staying < 7 days. There were 30 deaths (11%) with mortality highest among the unimmunised (n= 13, 44%) and severe pneumonia (39.5%) was the commonest complication.The average cost estimate to the health care delivery system to treat a child with measles was (114.5 USD). Human resource (79.33USD, SD 4.63) and treatment costs (21.98USD, SD 22.77) were the largest expenses.ConclusionsMortality among children with measles was high and occurrence of complications common. The estimated average direct health care cost of treating a measles case in the National Referral Hospital was considerably high. Further research is required to estimate the cost to the family and society in managing a child with measles.
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- 2023
22. Action leveraging evidence to reduce perinatal mortality and morbidity (ALERT): study protocol for a stepped-wedge cluster-randomised trial in Benin, Malawi, Tanzania and Uganda
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Akuze, Joseph, Annerstedt, Kristi Sidney, Benova, Lenka, Chipeta, Effie, Dossou, Jean-Paul, Gross, Mechthild M., Kidanto, Hussein, Marchal, Bruno, Alvesson, Helle Mölsted, Pembe, Andrea B., van Damme, Wim, Waiswa, Peter, Hanson, Claudia, Namazzi, Gertrude, Babirye, Josephine, Wanduru, Philip, Orsini, Nicola, Unkels, Regine, Pleguezuelo, Virginia Castellano, Snijders, Rian, Delvaux, Therese, Kandeya, Bianca, Mussa, Razak, Meja, Samuel, Stones, William, Nyirenda, Yesaya Z., Laure, Ahossi Angèle Florence, Sognonvi, Antoinette, Vigan, Armelle, Hamed, Banougnin Bolade, Bello, Kéfilath, Metogni, Christelle Boyi, Houngbo, Gisele, Agballa, Gottfried, Hounkpati, Hashim, Agbla, Schadrac, Welsh, Joanne, Abeid, Muzdalifat, Mwansisya, Tumbwene, Alwy Al-Beity, Fadhlun M., Julius, Zamoyoni, Mkoka, Dickson, Mselle, Lilian T., Mwilike, Beatrice, Naburi, Helga, Ayebare, Elizabeth O., Moller, Ann-Beth Nygaard, Ayebare, Elizabeth Ombeva, Hounkpatin, Hashim, Gandaho, Pacos, Kidanto, Hussein L., Mselle, Lilian, Gross, Mechthild, Van Damme, Wim, Hall, Jennifer, Lampa, Erik, Qureshi, Zahida, Gerontology, and Frailty in Ageing
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Malawi ,Malawi/epidemiology ,Respectful maternity care ,Midwifery ,Tanzania ,Health system intervention ,Study Protocol ,Hospital ,03 medical and health sciences ,0302 clinical medicine ,Obstetrics and Gynaecology ,Benin ,Humans ,Uganda ,030212 general & internal medicine ,Sub-Saharan Africa ,030503 health policy & services ,Health Policy ,Infant, Newborn ,Uganda/epidemiology ,Public Health, Environmental and Occupational Health ,Tanzania/epidemiology ,Perinatal health ,3. Good health ,perinatal mortality ,Childbirth ,perinatal death ,Female ,pregnancy ,Maternal health ,Morbidity ,Geriatrics and Gerontology ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,Intrapartum care - Abstract
Background Insufficient reductions in maternal and neonatal deaths and stillbirths in the past decade are a deterrence to achieving the Sustainable Development Goal 3. The majority of deaths occur during the intrapartum and immediate postnatal period. Overcoming the knowledge-do-gap to ensure implementation of known evidence-based interventions during this period has the potential to avert at least 2.5 million deaths in mothers and their offspring annually. This paper describes a study protocol for implementing and evaluating a multi-faceted health care system intervention to strengthen the implementation of evidence-based interventions and responsive care during this crucial period. Methods This is a cluster randomised stepped-wedge trial with a nested realist process evaluation across 16 hospitals in Benin, Malawi, Tanzania and Uganda. The ALERT intervention will include four main components: i) end-user participation through narratives of women, families and midwifery providers to ensure co-design of the intervention; ii) competency-based training; iii) quality improvement supported by data from a clinical perinatal e-registry and iv) empowerment and leadership mentoring of maternity unit leaders complemented by district based bi-annual coordination and accountability meetings. The trial’s primary outcome is in-facility perinatal (stillbirths and early neonatal) mortality, in which we expect a 25% reduction. A perinatal e-registry will be implemented to monitor the trial. Our nested realist process evaluation will help to understand what works, for whom, and under which conditions. We will apply a gender lens to explore constraints to the provision of evidence-based care by health workers providing maternity services. An economic evaluation will assess the scalability and cost-effectiveness of ALERT intervention. Discussion There is evidence that each of the ALERT intervention components improves health providers’ practices and has modest to moderate effects. We aim to test if the innovative packaging, including addressing specific health systems constraints in these settings, will have a synergistic effect and produce more considerable perinatal mortality reductions. Trial registration Pan African Clinical Trial Registry (www.pactr.org): PACTR202006793783148. Registered on 17th June 2020.
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- 2021
23. Maternal, reproductive and obstetric factors associated with preterm births in Mulago Hospital, Kampala, Uganda: a case control study
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Elizabeth Ayebare, Peter Ntuyo, Oliver Ombeva Malande, and Gorrette Nalwadda
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preterm birth ,postpartum ,risk factors ,newborn ,uganda ,Medicine - Abstract
INTRODUCTION: Preterm birth, a leading cause of neonatal mortality accounts for 35 percent of all neonatal deaths worldwide. Uganda's high preterm birth rate of 13.6 per 1000 live births ranks 28th in the world. Efforts at reducing these pre-term births must entail interventions that target any associated risk factors. This study therefore aimed at identifying and describing the risk factors for preterm births among mothers delivering in Mulago Hospital. METHODS: This was a case control study among postpartum women in Mulago Hospital. Ninety nine women with preterm newborns were recruited as cases and 193 with full term babies were the controls. A semi-structured questionnaire was used to collect data. Data was entered into Epidata version 3.1 and exported to STATA 11 for univariate analysis and multivariate analysis by logistic regression. RESULTS: Risk factors for preterm birth included maternal height less than 1.5 meters (OR 131.08 (20.35-844.02)), rural residence (OR 6.56(2.68-16.10)) and failure to attend antenatal care clinic (OR 8.88(1.44-54.67)). Pregnancy related risk factors included PPROM (OR 287.11(49.26-1673.28)), antepartum haemorrhage (OR 7.33(1.23-43.72)) and preeclampsia/eclampsia (OR 16.24(3.11-84.70)). CONCLUSION: Preterm birth is more likely to occur in women of short stature, living in rural areas and those who do not attend antenatal care clinic. The preterm birth risk is higher for women who get PPROM, APH and preeclampsia/eclampsia in pregnancy. Early recognition and management of these high risk conditions among pregnant women may lead to a reduction in preterm birth rates.
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- 2018
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24. Tackling antimicrobial resistance across sub-Saharan Africa : current challenges and implications for the future
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Brian Godman, Abiodun Egwuenu, Evelyn Wesangula, Natalie Schellack, Aubrey Chichonyi Kalungia, Celda Tiroyakgosi, Joyce Kgatlwane, Julius C. Mwita, Okwen Patrick, Loveline Lum Niba, Adefolarin A. Amu, Racheal Tomilola Oguntade, Mobolaji Eniola Alabi, Nondumiso B. Q. Ncube, Israel Abebrese Sefah, Joseph Acolatse, Robert Incoom, Anastasia Nkatha Guantai, Margaret Oluka, Sylvia Opanga, Ibrahim Chikowe, Felix Khuluza, Francis K. Chiumia, Collins Edward Jana, Francis Kalemeera, Ester Hango, Joseph Fadare, Olayinka O. Ogunleye, Bernard E. Ebruke, Johanna C. Meyer, Amos Massele, Oliver Ombeva Malande, Dan Kibuule, Otridah Kapona, Trust Zaranyika, Mutsa Bwakura-Dangarembizi, Tapiwanashe Kujinga, Zikria Saleem, Amanj Kurdi, Moyad Shahwan, Ammar Abdulrahman Jairoun, Janney Wale, and Adrian J Brink
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Drug Resistance, Bacterial ,Humans ,Pharmacology (medical) ,General Medicine ,Africa South of the Sahara ,Anti-Bacterial Agents ,RS - Abstract
Introduction: Antimicrobial resistance (AMR) is a concern as this increases morbidity, mortality, and costs, with sub-Saharan Africa having the highest rates globally. Concerns with rising AMR have resulted in international, Pan-African, and country activities including the development of national action plans (NAPs). However, there is variable implementation across Africa with key challenges persisting. Areas covered: Consequently, there is an urgent need to document current NAP activities and challenges across sub-Saharan Africa to provide future guidance. This builds on a narrative review of the literature. Expert Opinion: All surveyed sub-Saharan African countries have developed their NAPs; however, there is variable implementation. Countries including Botswana and Namibia are yet to officially launch their NAPs with Eswatini only recently launching its NAP. Cameroon is further ahead with its NAP than these countries; though there are concerns with implementation. South Africa appears to have made the greatest strides with implementing its NAP including regular monitoring of activities and instigation of antimicrobial stewardship programs. Key challenges remain across Africa. These include available personnel, expertise, capacity, and resources to undertake agreed NAP activities including active surveillance, lack of focal points to drive NAPs, and competing demands and priorities including among donors. These challenges are being addressed, with further co-ordinated efforts needed to reduce AMR.
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- 2022
25. Management of Multisystem Inflammatory Syndrome in Children (MIS-C) in resource limited settings: The Kenyan Experience
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MIGOWA, ANGELA NYANGORE, primary, Samia, Pauline, additional, Shah, Jasmit, additional, Rossi, Sean del, additional, Kenei, Chemutai, additional, Malande, Oliver Ombeva, additional, Ayaya, Joy, additional, Jeruto, Daisy, additional, Oyiengo, Laura, additional, and Lewandowski, Laura, additional
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- 2022
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26. Tackling antimicrobial resistance across sub-Saharan Africa: current challenges and implications for the future
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Godman, Brian, primary, Egwuenu, Abiodun, additional, Wesangula, Evelyn, additional, Schellack, Natalie, additional, Kalungia, Aubrey Chichonyi, additional, Tiroyakgosi, Celda, additional, Kgatlwane, Joyce, additional, Mwita, Julius C., additional, Patrick, Okwen, additional, Niba, Loveline Lum, additional, Amu, Adefolarin A., additional, Oguntade, Racheal Tomilola, additional, Alabi, Mobolaji Eniola, additional, Ncube, Nondumiso B. Q., additional, Sefah, Israel Abebrese, additional, Acolatse, Joseph, additional, Incoom, Robert, additional, Guantai, Anastasia Nkatha, additional, Oluka, Margaret, additional, Opanga, Sylvia, additional, Chikowe, Ibrahim, additional, Khuluza, Felix, additional, Chiumia, Francis K., additional, Jana, Collins Edward, additional, Kalemeera, Francis, additional, Hango, Ester, additional, Fadare, Joseph, additional, Ogunleye, Olayinka O., additional, Ebruke, Bernard E., additional, Meyer, Johanna C., additional, Massele, Amos, additional, Malande, Oliver Ombeva, additional, Kibuule, Dan, additional, Kapona, Otridah, additional, Zaranyika, Trust, additional, Bwakura-Dangarembizi, Mutsa, additional, Kujinga, Tapiwanashe, additional, Saleem, Zikria, additional, Kurdi, Amanj, additional, Shahwan, Moyad, additional, Jairoun, Ammar Abdulrahman, additional, Wale, Janney, additional, and Brink, Adrian J, additional
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- 2022
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27. Nursing Partnership Activities, Components, and Outcomes: Health Volunteers Overseas in Uganda 2001–2016
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Scovia Nalugo Mbalinda, Rose Chalo Nabirye, Elizabeth Ayebare Ombeva, S. Danielle Brown, and Jeanne M. Leffers
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collaboration ,partnerships ,education ,evaluation ,nursing ,Public aspects of medicine ,RA1-1270 - Abstract
Nurses increasingly form global health partnerships through academic and voluntary organizations that are designed to improve health outcomes. Many such partnerships are funded for specific time periods and have short- or long-term goals to achieve during the partnership. Other partnerships are sustained for longer periods of time through the efforts of partners committed to their joint work. The case example of the Health Volunteers Overseas Nursing Education partnership in Kampala, Uganda, demonstrates key components of partnerships that promote sustainability of programs. This case example is analyzed using literature that reports partnership models to identify those factors that have led to sustainability. Additionally, both objective and subjective program outcomes are reported. Recommendations for further evaluation are included.
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- 2017
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28. Encouraging improvement in HPV vaccination coverage among adolescent girls in Kampala, Uganda
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Patrick, Lydia, primary, Bakeera-Kitaka, Sabrina, additional, Rujumba, Joseph, additional, and Malande, Oliver Ombeva, additional
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- 2022
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29. My covid-19 experience: picking up the pieces
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Oliver Ombeva Malande
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2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,SARS-CoV-2 ,business.industry ,Health Personnel ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,COVID-19 ,Articles ,General Medicine ,Virology ,Humans ,Medicine ,business ,Pandemics - Abstract
Nil
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- 2020
30. Global vaccinology training: Report from an ADVAC workshop
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Duclos, Philippe, Martinez, Lindsay, MacDonald, Noni, Asturias, Edwin, Nohynek, Hanna, Lambert, Paul-Henri, Afaayo, Rachel, Andersson, Lizzelott, Angele, Sandra, Arora, Narendra, Ashfield, Rebecca, Beal, Amanda Shortell, Bose, Anuradha, Comiadiere, Behazine, Costa Clemens, Sue Ann, Cutland, Clare, Dochez, Carine, Finan, Amy, Finn, Adam, Gambillara Fonck, Veronica, Kagina, Benjamin, Kane, Ndeye Coumba Toure, Koeck, Jean-Louis, Kraehenbuhl, Jean-Pierre, Lindstrand, Ann, Lynch, Julia Anne, Macdonald, Noni, Malande, Oliver Ombeva, Meric, Claude, Mosina, Liudmila, Muloiwa, Rudzani, Pansier, Benedicte, Pattyn, Jade, Paul, Stephane, Phalipon, Armelle, Podda, Audino, Rodewald, Lance, Scott, Anthony, Talbot, Keipp, Tikoo, Suresh, Tipping, Jane, van Damme, Pierre, Wang, Likui, Wouters, Ine, University of Geneva [Switzerland], Dalhousie University [Halifax], University of Colorado Anschutz [Aurora], National Institute for Health and Welfare [Helsinki], Université de Genève (UNIGE), all participants of the Global Vaccinology Training Workshop : Rachel AFAAYO, East Africa Centre for Vaccines and Immunization, Uganda, Lizzelott ANDERSSON, Carlos Slim Foundation, with endorsement of the National Autonomous University of Mexico, Mexico, Sandra ANGELE, Fondation Mérieux, France, Narendra ARORA, Child Foundation/INCLEN, India, Rebecca ASHFIELD, University of Oxford/Jenner Institute, UK, Edwin ASTURIAS, University of Colorado, USA, Amanda SHORTELL BEAL, Bill & Melinda Gates Foundation, USA Anuradha BOSE, Christian Medical College, India, Béhazine COMBADIERE, INSERM, France, Sue Ann COSTA CLEMENS, Institute for Global Health-University of Siena, Italy, Clare CUTLAND, University of the Witwatersrand, South Africa, Carine DOCHEZ, University of Antwerp, Belgium, Philippe DUCLOS, University of Geneva, Switzerland, Amy FINAN, Sabin Vaccine Institute, USA, Adam FINN, University of Bristol, UK, Veronica GAMBILLARA FONCK, Limmatech Biologics, Switzerland, Benjamin KAGINA, University of Cape Town, South Africa, Ndeye Coumba Touré KANE, Université de Dakar, Sénégal, Jean-Louis KOECK, Direction Centrale du Service de Santé des Armées, France, Jean-Pierre KRAEHENBUHL, Health Sciences E-training Foundation, Switzerland, Paul-Henri LAMBERT, University of Geneva, Switzerland, Ann LINDSTRAND, World Health Organization, Switzerland, Julia Anne LYNCH, International Vaccine Institute, Korea, Noni MACDONALD, Dalhousie University, Canada, Oliver Ombeva MALANDE, Africa Centre For Vaccines and Immunization, Kenya, Lindsay MARTINEZ, Freelance Consultant, Switzerland, Claude MERIC, Freelance Consultant, Switzerland, Liudmila MOSINA, WHO Regional Office for Europe, Denmark, Rudzani MULOIWA, University of Cape Town, South Africa, Hanna NOHYNEK, National Institute for Health and Welfare, Finland, Bénédicte PANSIER, Fondation Mérieux, France, Jade PATTYN, University of Antwerp, Belgium, Stéphane PAUL, Université Jean Monet, France, Armelle PHALIPON, Institut Pasteur, France, Audino PODDA, GSK Vaccines Institute for Global Health, Italy, Lance RODEWALD, Chinese Center for Disease Control and Prevention, China, Anthony SCOTT, London School of Hygiene and Tropical Medicine, UK, Keipp TALBOT, Vanderbilt University Medical Center, USA, Suresh TIKOO, University of Saskatchewan, Canada, Jane TIPPING, Faculty of Medicine, University of Toronto, Canada, Pierre VAN DAMME, University of Antwerp, Vaccine and Infectious Diseases Institute, Belgium, Likui WANG, University of Chinese Academy of Sciences, China, Ine WOUTERS, University of Antwerp, Belgium., Université de Genève = University of Geneva (UNIGE), and Global Vaccinology Training Works
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Computer science ,Best practice ,030231 tropical medicine ,Training (civil) ,03 medical and health sciences ,0302 clinical medicine ,Adult education ,ComputingMilieux_COMPUTERSANDEDUCATION ,Humans ,030212 general & internal medicine ,Workshop ,Constraint (mathematics) ,Information exchange ,Vaccines ,General Veterinary ,General Immunology and Microbiology ,Public Health, Environmental and Occupational Health ,Global ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Vaccinology ,Engineering management ,Infectious Diseases ,Molecular Medicine ,Education, Medical, Continuing ,Human medicine ,Advanced vaccinology training ,Vaccinology training - Abstract
At a workshop on 7-8 November 2018 the leaders of 26 advanced vaccinology courses met to carry out an extensive review of the existing courses worldwide, in order to identify education gaps and future needs and discuss potential collaboration. The main conclusions of the workshop concerned: opportunities for strengthening and expanding the global coverage of vaccinology training; evaluation of vaccinology courses; updating knowledge after the course; how to facilitate post-course 'cascade' training; developing and sharing best practices; the application of online and innovative approaches in adult education; and how to reduce costs and facilitate wider access to vaccinology training. The importance of collaboration and information exchange through networks of alumni and between courses was stressed. A web platform to provide information about existing courses for potential applicants is needed. Lack of sustainable funding is a constraint for vaccinology training and needs to be addressed. (C) 2019 The Authors. Published by Elsevier Ltd.
- Published
- 2019
31. Birth preparedness, complication readiness and male partner involvement for obstetric emergencies in rural Rwanda
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Richard Kalisa and Oliver Ombeva Malande
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antenatal care ,barriers to access ,male partner involvement ,pregnancy ,Medicine - Abstract
INTRODUCTION: birth preparedness and complication readiness (BP/CR) promotes timely access to skilled maternal and neonatal services, active preparation and decision-making for seeking health care to prevent any adverse outcomes. The aim was to assess level of male partner (MP) involvement in the birth plan, the attitude of the women towards maternal care and factors associated with BP/CR among obstetric referrals in rural Rwanda. METHODS: this was a cross-sectional study among 350 pregnant women who were admitted as referrals at Ruhengeri hospital, between July 2015 and November 2015. Data was collected on socio-demographics, level of MP's participation in maternal health care and domestic activities, women's attitude towards involvement of men in maternal care and BP/CR. Any woman who arranged to have a birth companion, made a plan of where to deliver from, received health education on pregnancy and childbirth complications, saved money in case of pregnancy complication and had attended antenatal care (ANC) at least 4 times, was deemed as having made a birth plan. RESULTS: the mean age was 27.7 years, while mean age of the spouse was 31.3 years. Majority of the women (n=193; 55.1%) and their spouse (n=208; 59.4%) had completed primary education. Men's role was found to be mainly in the area of financial support. The level of men ANC attendance was low (n=103; 29.4%), while 78 (22.3%) women were accompanied to the labor ward. However, there was a strong opposition to the physical presence of MP in the labor room (n=178; 50.9%). The main reason cited by women opposing MP presence is that it is against their culture for a man to witness the delivery of a baby. On multivariable analysis, maternal education level of secondary or higher adjusted odds ratio [AOR] 1.4 95% CI (1.8-2.6), formal occupation of spouse, AOR 2.4 95% CI (1.4-4.2) and personnel checked during ANC being community health worker AOR 2.2, 95% CI; (1.3,3.7) were associated with being well prepared. CONCLUSION: male involvement in pregnancy and antenatal care is low. To increase men involvement in birth plan addressing cultural barriers and refraining care-givers and health facility policies towards family delivery is paramount.
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- 2016
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32. Additional file 1 of Management of Multisystem Inflammatory Syndrome in Children (MIS-C) in resource limited settings: The Kenyan Experience
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Migowa, Angela, Samia, Pauline, del Rossi, Sean, Malande, Oliver Ombeva, Shah, Jasmit, Kenei, Chemutai, Ayaya, Joy, Jeruto, Daisy, Oyiengo, Laura, and Lewandowski, Laura
- Abstract
Additional file 1.
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- 2022
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33. Challenges and Innovations Brought about by the COVID-19 Pandemic Regarding Medical and Pharmacy Education Especially in Africa and Implications for the Future
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Etando, Ayukafangha, primary, Amu, Adefolarin A., additional, Haque, Mainul, additional, Schellack, Natalie, additional, Kurdi, Amanj, additional, Alrasheedy, Alian A., additional, Timoney, Angela, additional, Mwita, Julius C., additional, Rwegerera, Godfrey Mutashambara, additional, Patrick, Okwen, additional, Niba, Loveline Lum, additional, Boahen-Boaten, Baffour Boaten, additional, Tabi, Felicity Besong, additional, Amu, Olufunke Y., additional, Acolatse, Joseph, additional, Incoom, Robert, additional, Sefah, Israel Abebrese, additional, Guantai, Anastasia Nkatha, additional, Opanga, Sylvia, additional, Chikowe, Ibrahim, additional, Khuluza, Felix, additional, Kibuule, Dan, additional, Kalemeera, Francis, additional, Hango, Ester, additional, Lates, Jennie, additional, Fadare, Joseph, additional, Ogunleye, Olayinka O., additional, Saleem, Zikria, additional, Oosthuizen, Frasia, additional, Cordier, Werner, additional, Matlala, Moliehi, additional, Meyer, Johanna C., additional, Schellack, Gustav, additional, Massele, Amos, additional, Malande, Oliver Ombeva, additional, Kalungia, Aubrey Chichonyi, additional, Sichone, James, additional, Banda, Sekelani S., additional, Zaranyika, Trust, additional, Campbell, Stephen, additional, and Godman, Brian, additional
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- 2021
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34. Adverse events following immunization reporting and impact on immunization services in informal settlements in Nairobi, Kenya: a prospective mixed-methods study
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Oliver Ombeva, Malande, Deogratias, Munube, Rachel Nakatugga, Afaayo, Carolyne, Chemweno, Mutunga, Nzoka, James, Kipsang, Andrew Munyalo, Musyoki, Johanna Catharina, Meyer, Leonidah Nyamusi, Omayo, and Lawrence, Owino-Okongo
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immunization programs ,child ,Research ,Vaccination ,Infant ,focus groups ,informal settlements ,Kenya ,Adverse Drug Reaction Reporting Systems ,Humans ,Immunization ,Prospective Studies ,Vaccination Hesitancy - Abstract
Introduction:adverse events following immunization (AEFIs) are thought to contribute to cases of vaccine hesitancy, yet little data exists describing the state of reporting and management of AEFIs. This study investigated the occurrence and influence of AEFIs on vaccine hesitancy in an informal settlement of Nairobi. Methods:this was a prospective mixed-methods study involving 7 focus group discussions, 8 key informant interviews and 457 face-to-face interviews with caregivers. Caregivers were recruited at/or before the 6-week clinic visit and assessed for occurrence of AEFIs in their children at the subsequent 10- and 14-week visits and a follow-up two weeks following the 14 weeks visit via phone calls. Results:in this study, 12.3% (56/457) of the infants experienced an AEFI. Of these, 19 did not report for the next scheduled vaccine. Fever was the most common AEFI, for which most caregivers (66.7%) used paracetamol as antipyretic, while 20.8% sought help from a nearby health facility. Three of the 56 AEFIs (convulsions) that occurred in study participants could be classified as severe reactions. Diphtheria, pertussis and tetanus (DPT) 3 completion rate was 75.3%. Most (96.4%) caregivers considered immunization an important strategy for child survival. Vaccine hesitancy occurred among 3.6% of participants, 30% of whom attributed their hesitancy to occurrence of AEFIs. The review of health records revealed that no AEFI had been reported from any of the study facilities. Conclusion:cases of adverse events following immunization are not reported in Mathare Valley and they do have implications for vaccine hesitancy by some caregivers.
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- 2021
35. Embedding problem solving and use of data with routine supply chain procedures: District leadership and team-based approaches improve product availability in Rwanda
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Alexis Heaton, Amanda Ombeva, Deogratias Leopold, Golbert Kazoza, Patrick Nganji, Cathy Mugeni, Megan Noel, and Yasmin Chandani
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Supply Chain ,Product Availability ,District Leadership ,Volunteer Community Health ,Quality Improvement Team ,Therapeutics. Pharmacology ,RM1-950 ,Pharmacy and materia medica ,RS1-441 - Published
- 2014
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36. The current situation regarding long-acting insulin analogues including biosimilars among selected African, Asian, European and South American countries : findings and implications for the future
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Brian Godman, Mainul Haque, Trudy Leong, Eleonora Allocati, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Carlos Vassalo, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M. Muksudul Alam, Iffat Jahan, Zubair Mahmood Kamal, Humaira Hasin, Munzur-E-Murshid, Shamsun Nahar, Monami Haque, Siddhartha Dutta, Jha Pallavi Abhayanand, Rimple Jeet Kaur, Godfrey Mutashambara Rwegerera, Renata Cristina Rezende Macedo do Nascimento, Isabella Piassi Dias Godói, Mohammed Irfan, Adefolarin A. Amu, Patrick Matowa, Joseph Acolatse, Robert Incoom, Israel Abebrese Sefah, Jitendra Acharya, Sylvia Opanga, Lisper Wangeci Njeri, David Kimonge, Hye-Young Kwon, SeungJin Bae, Karen Koh Pek Khuan, Abdullahi Rabiu Abubakar, Ibrahim Haruna Sani, Tanveer Ahmed Khan, Shahzad Hussain, Zikria Saleem, Oliver Ombeva Malande, Thereza Piloya-Were, Rosana Gambogi, Carla Hernandez Ortiz, Luke Alutuli, Aubrey Chichonyi Kalungia, Iris Hoxha, Vanda Marković-Peković, Biljana Tubic, Guenka Petrova, Konstantin Tachkov, Ott Laius, András Harsanyi, András Inotai, Arianit Jakupi, Svens Henkuzens, Kristina Garuoliene, Jolanta Gulbinovič, Magdalene Wladysiuk, Jakub Rutkowski, Ileana Mardare, Jurij Fürst, Stuart McTaggart, Sean MacBride-Stewart, Caridad Pontes, Corinne Zara, Eunice Twumwaa Tagoe, Rita Banzi, Janney Wale, and Mihajlo Jakovljevic
- Subjects
cross-national study ,Insulin glargine ,Long acting insulin ,medicine.medical_treatment ,India ,RS ,Competition (economics) ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Environmental health ,Republic of Korea ,medicine ,Hypoglycemic Agents ,Drug utilisation ,Pakistan ,biosimilars ,030212 general & internal medicine ,Africa ,drug utilisation ,Europe ,health policy ,insulin glargine ,prices ,Biosimilar Pharmaceuticals ,Health policy ,Original Research ,Biosimilars ,Bangladesh ,Prices ,030503 health policy & services ,Insulin ,Public Health, Environmental and Occupational Health ,Cross-national study ,Biosimilar ,medicine.disease ,Insulin, Long-Acting ,South american ,Public Health ,Business ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,Brazil ,medicine.drug - Abstract
Background:Diabetes mellitus rates continue to rise, which coupled with increasing costs of associated complications has appreciably increased global expenditure in recent years. The risk of complications are enhanced by poor glycaemic control including hypoglycaemia. Long-acting insulin analogues were developed to reduce hypoglycaemia and improve adherence. Their considerably higher costs though have impacted their funding and use. Biosimilars can help reduce medicine costs. However, their introduction has been affected by a number of factors. These include the originator company dropping its price as well as promoting patented higher strength 300 IU/ml insulin glargine. There can also be concerns with different devices between the manufacturers.Objective:To assess current utilisation rates for insulins, especially long-acting insulin analogues, and the rationale for patterns seen, across multiple countries to inform strategies to enhance future utilisation of long-acting insulin analogue biosimilars to benefit all key stakeholders.Our approach:Multiple approaches including assessing the utilisation, expenditure and prices of insulins, including biosimilar insulin glargine, across multiple continents and countries.Results:There was considerable variation in the use of long-acting insulin analogues as a percentage of all insulins prescribed and dispensed across countries and continents. This ranged from limited use of long-acting insulin analogues among African countries compared to routine funding and use across Europe in view of their perceived benefits. Increasing use was also seen among Asian countries including Bangladesh and India for similar reasons. However, concerns with costs and value limited their use across Africa, Brazil and Pakistan. There was though limited use of biosimilar insulin glargine 100 IU/ml compared with other recent biosimilars especially among European countries and Korea. This was principally driven by small price differences in reality between the originator and biosimilars coupled with increasing use of the patented 300 IU/ml formulation. A number of activities were identified to enhance future biosimilar use. These included only reimbursing biosimilar long-acting insulin analogues, introducing prescribing targets and increasing competition among manufacturers including stimulating local production.Conclusions:There are concerns with the availability and use of insulin glargine biosimilars despite lower costs. This can be addressed by multiple activities.
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- 2021
37. Strategies to improve antimicrobial utilization with a special focus on developing countries
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Mainul Haque, Renata Cristina Rezende Macedo do Nascimento, Abiodun Egwuenu, Johanna C Meyer, Adefolarin A Amu, Robert Incoom, Stephen Campbell, Sylvia Opanga, Iris Hoxha, Janney Wale, Dan Kibuule, Vanda Marković-Peković, Natalie Schellack, Adesola Olalekan, Loveline Lum Niba, Felix Khuluza, Abubakr A. Alfadl, Brian Godman, Thuy Nguyen Thi Phuong, Isabella Piassi Godói, Joseph Acolatse, Olayinka O Ogunleye, Amanj Kurdi, Zikria Saleem, Santosh Kumar, Salequl Islam, Aubrey Chichonyi Kalungia, Jacqueline Sneddon, Julius Chacha Mwita, Israel Abebrese Sefah, R. Andrew Seaton, Ibrahim Chikowe, Oliver Ombeva Malande, and Alice Pisana
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Quality management ,Science ,030106 microbiology ,Developing country ,Review ,General Biochemistry, Genetics and Molecular Biology ,antimicrobials ,patient initiatives ,RS ,03 medical and health sciences ,0302 clinical medicine ,Antibiotic resistance ,Ambulatory care ,Pandemic ,medicine ,Antimicrobial stewardship ,030212 general & internal medicine ,Misinformation ,antimicrobial resistance ,Intensive care medicine ,misinformation ,Ecology, Evolution, Behavior and Systematics ,business.industry ,Public health ,Paleontology ,COVID-19 ,surgical site infections ,vaccines ,healthcare-associated infections ,Space and Planetary Science ,antimicrobial stewardship programs ,lower- and middle-income countries ,business - Abstract
Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity, mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, nationally and regionally to enhance appropriate antibiotic utilization across sectors to reduce AMR, with the overuse of antibiotics exacerbated by the COVID-19 pandemic. Effectively tackling AMR is crucial for all countries. Principally a narrative review of ongoing activities across sectors was undertaken to improve antimicrobial use and address issues with vaccines including COVID-19. Point prevalence surveys have been successful in hospitals to identify areas for quality improvement programs, principally centering on antimicrobial stewardship programs. These include reducing prolonged antibiotic use to prevent surgical site infections. Multiple activities centering on education have been successful in reducing inappropriate prescribing and dispensing of antimicrobials in ambulatory care for essentially viral infections such as acute respiratory infections. It is imperative to develop new quality indicators for ambulatory care given current concerns, and instigate programs with clear public health messaging to reduce misinformation, essential for pandemics. Regular access to effective treatments is needed to reduce resistance to treatments for HIV, malaria and tuberculosis. Key stakeholder groups can instigate multiple initiatives to reduce AMR. These need to be followed up.
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- 2021
38. Symptomatic infantile helicobacter pylori gastritis infection in indigenous african infants: a case series
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Oliver Ombeva Malande
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infantile ,helicobacter pylori ,gastritis ,infection ,Medicine - Abstract
Helicobacter pylori gastritis infection rate increases with age. Higher rates have however been reported among young people in the developing countries of the world. The infection however has rarely been reported in infants, especially in Africa. This case series describes three cases of Helicobacter pylori gastritis infection as diagnosed in three infants. The goal is to raise the suspicion index of medical practitioners about the possibility of this this infection among infants who present with suggestive symptoms. On three separate occasions in 2012 and 2013, three ill, indigenous, black African female infants aged 4, 6 and 7 months, were brought to hospital with symptoms ranging from fever, refusal to feed, diarrhoea, restlessness, vomiting and irritability. In each case, systemic examination findings were unremarkable. After several laboratory investigations, each infant was found to have Helicobacter pylori infection following positive blood antibody (using Tell Me Fast H. Pylori antibody serum and Plasma test manufactured by Biocan Diagnostics Canada) and fecal HpSA ImmunoCardSTAT antigen tests. Repeat stool antigen test was negative in each case after completion of the recommended triple therapy. Helicobacter pylori infection has been rarely reported among infants. This case series highlights the need for health care providers to have a high index of suspicion so that infants with suggestive symptoms, especially in settings with high Helicobacter pylori colonization prevalence can be evaluated for Helicobacter pylori gastritis infection.
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- 2014
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39. Understanding the pathophysiology of Covid-19 : a review of emerging concepts
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Malande, Oliver Ombeva, Musyoki, Andrew M., Meyer, Johanna Catharina, Godman, Brian, and Masika, Jacob
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RS - Abstract
Coronavirus disease 2019 (COVID-19) was first described in the Chinese city of Wuhan in December 2019. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the causative agent. It was quickly established that SARS-CoV-2 is transmitted through respiratory droplets when individuals are in close contact with asymptomatic or symptomatic carriers. The incubation period is around 5 days, and it is estimated in up to 97% of infected individuals symptoms will present within 14 days. To date, new presentations are being described. COVID-19 presentation spans from asymptomatic, mild disease to sever systemic disease. The most commonly described symptoms include pneumonia, dyspnea, dry cough, headache and fever. Various companies have developed quantitative polymerase chain reaction (qPCR) assays for the detection of SARS-CoV-2 from mainly nasopharyngeal or throat swab. Several serological tests have also now been approved for use. A lot has been learnt of the laboratory and clinical characteristics of this disease, questions still remain as to the actual pathophysiology leading to either asymptomatic, mild or sever disease. However, despite this, the disease carries the risk of sepsis and acute respiratory failure with increased number of death tolls, forced social distance and lockdowns in many countries. This review highlights key mechanisms that have been proposed to contribute to COVID-19 progression from viral entry to multisystem organ failure, as well as the central role of the immune response in successful viral clearance or progression to death. With the exception of when there is a pre-existing co-morbidity, most reports indicate sever disease occurring in the older population and mild disease or asymptomatic infection in children. Over 120 SARS-CoV-2 vaccines are at various stages of development. As the roll-out of approved vaccines is happens at different rates globally, the prescribed methods to reduce transmission remain facemasks, social distancing, and contact tracing.
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- 2021
40. Strategies to Improve Antimicrobial Utilization with a Special Focus on Developing Countries
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Godman, Brian, primary, Egwuenu, Abiodun, additional, Haque, Mainul, additional, Malande, Oliver Ombeva, additional, Schellack, Natalie, additional, Kumar, Santosh, additional, Saleem, Zikria, additional, Sneddon, Jacqueline, additional, Hoxha, Iris, additional, Islam, Salequl, additional, Mwita, Julius, additional, do Nascimento, Renata Cristina Rezende Macedo, additional, Dias Godói, Isabella Piassi, additional, Niba, Loveline Lum, additional, Amu, Adefolarin A., additional, Acolatse, Joseph, additional, Incoom, Robert, additional, Sefah, Israel Abebrese, additional, Opanga, Sylvia, additional, Kurdi, Amanj, additional, Chikowe, Ibrahim, additional, Khuluza, Felix, additional, Kibuule, Dan, additional, Ogunleye, Olayinka O., additional, Olalekan, Adesola, additional, Markovic-Pekovic, Vanda, additional, Meyer, Johanna C., additional, Alfadl, Abubakr, additional, Phuong, Thuy Nguyen Thi, additional, Kalungia, Aubrey C., additional, Campbell, Stephen, additional, Pisana, Alice, additional, Wale, Janney, additional, and Seaton, R. Andrew, additional
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- 2021
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41. The Role of Immunization In Preventing Infection In Children With Sickle Cell Disease
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Ombeva Malande
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- 2021
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42. COVID-19 VACCINE DEVELOPMENT: Options and implications for Africa KMA COVID-19 CASE MANAGEMENT WEBINAR
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Ombeva Malande
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- 2021
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43. The Rationale of Pneumococcal and Meningococcal Vaccination in Paediatric Population
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Ombeva Malande
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- 2021
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44. VACCINES AND DRUG DEVELOPMENT AMIDST COVID19_27th June 2020_Ombeva Malande
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Dr. Ombeva O. Malande
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- 2021
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45. COVID VACCINES: Facts Myths and Misconceptions AMREF flying doctors Webinar
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Ombeva Malande
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- 2021
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46. Epidemiology, Clinical Features and Outcomes Of Children With COVID-19 in Kenya
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Ombeva Malande
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- 2021
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47. COVID-19 AND ITS EFFECT ON MEASLES VACCINATION PROGRAMS IN AFRICA: Strategies to Mitigate Emerging Challenges Scope of the presentation
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Ombeva Malande
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- 2021
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48. My covid-19 experience: picking up the pieces
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Ombeva Malande, Oliver, primary
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- 2020
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49. Upper GI bleeding among neonates admitted to Mulago Hospital, Kampala, Uganda: a prospective cohort study
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Ombeva, OM, Ndeezi, G, and Mugalu, J
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- 2013
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50. Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future
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Ogunleye, Olayinka O., primary, Basu, Debashis, additional, Mueller, Debjani, additional, Sneddon, Jacqueline, additional, Seaton, R. Andrew, additional, Yinka-Ogunleye, Adesola F., additional, Wamboga, Joshua, additional, Miljković, Nenad, additional, Mwita, Julius C., additional, Rwegerera, Godfrey Mutashambara, additional, Massele, Amos, additional, Patrick, Okwen, additional, Niba, Loveline Lum, additional, Nsaikila, Melaine, additional, Rashed, Wafaa M., additional, Hussein, Mohamed Ali, additional, Hegazy, Rehab, additional, Amu, Adefolarin A., additional, Boahen-Boaten, Baffour Boaten, additional, Matsebula, Zinhle, additional, Gwebu, Prudence, additional, Chirigo, Bongani, additional, Mkhabela, Nongabisa, additional, Dlamini, Tenelisiwe, additional, Sithole, Siphiwe, additional, Malaza, Sandile, additional, Dlamini, Sikhumbuzo, additional, Afriyie, Daniel, additional, Asare, George Awuku, additional, Amponsah, Seth Kwabena, additional, Sefah, Israel, additional, Oluka, Margaret, additional, Guantai, Anastasia N., additional, Opanga, Sylvia A., additional, Sarele, Tebello Violet, additional, Mafisa, Refeletse Keabetsoe, additional, Chikowe, Ibrahim, additional, Khuluza, Felix, additional, Kibuule, Dan, additional, Kalemeera, Francis, additional, Mubita, Mwangana, additional, Fadare, Joseph, additional, Sibomana, Laurien, additional, Ramokgopa, Gwendoline Malegwale, additional, Whyte, Carmen, additional, Maimela, Tshegofatso, additional, Hugo, Johannes, additional, Meyer, Johanna C., additional, Schellack, Natalie, additional, Rampamba, Enos M., additional, Visser, Adel, additional, Alfadl, Abubakr, additional, Malik, Elfatih M., additional, Malande, Oliver Ombeva, additional, Kalungia, Aubrey C., additional, Mwila, Chiluba, additional, Zaranyika, Trust, additional, Chaibva, Blessmore Vimbai, additional, Olaru, Ioana D., additional, Masuka, Nyasha, additional, Wale, Janney, additional, Hwenda, Lenias, additional, Kamoga, Regina, additional, Hill, Ruaraidh, additional, Barbui, Corrado, additional, Bochenek, Tomasz, additional, Kurdi, Amanj, additional, Campbell, Stephen, additional, Martin, Antony P., additional, Phuong, Thuy Nguyen Thi, additional, Thanh, Binh Nguyen, additional, and Godman, Brian, additional
- Published
- 2020
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