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Generally, two topics with vastly different terminology probably indicate different implied concepts. However, these topics themselves might share common references (bibliographic coupling), which suggest the underlying joint concept. Therefore, searching for these joint concepts in different topics would be of scientific interest. Previous studies have measured the similarity between topics based on comparison of the topics' word probability distributions. In contrast, this paper presents an approach for measuring the similarity between topics based on the bibliographic coupling. Besides, the similarity is independent of the topic's word probability distributions generated by a Latent Dirichlet Allocation (LDA) model. The proposed approach was evaluated using its counterpart (intra-topic similarity), baseline topic similarity matrices, and cosine measure. The method was exampled on brain cancer patents. A cross-topic similarity network of eight topics showcases 28 cross-topic pairs to profile which topics were associated with particular topics. Interestingly, some of the 28 combinations may be of scientific interest. For instance, the findings of the top five cross-topic pairs suggest that “growth of cancer cells” and “imbalances in the hormones” have common knowledge sources with the highest similarity value. These two entirely different concepts may suggest some common causative factors within the field. We believe that finding such an association between unrelated innovative inventions across various industries may help public and private research units in planning research direction and serve as a reference for future research.

The modern logistics industry in relation to economic growth and carbon emission has opened new strategic perspectives. Recent research work have analyzed such complex interference from a broad perspective. However, analyzing this overlap needs comprehensive insight into the logistics industry while simultaneously estimating its short-run and long-run effects from regional aspects due to continue-evolving factors and their impact on it. This paper competently analyzes logistics industry components in connection with economic prosperity, energy consumption, trade development, and carbon emission from a more specific regional perspective of a developing country. Methodologically, an autoregressive distributive lag model (ARDL) is employed using correlative evaluation of the dynamic factors and their interactive impact in short and long run on this relation, based on time-series data of Pakistan from 1990 to 2019. The study results endorse the previous studies’ outcomes by recognizing that an increase in carbon emission depends on trade development, energy usage, economic development, and the logistics industry’s various components except for air logistics. However, study results show a unidirectional long-run causality directing from economic development, logistics industry, energy utilization, and trade development to carbon emission. Moreover, these results reveal that this emission is the leading factor to introduce stringent emission standards that further overlap with regional demographics trends, i.e., carbon emission implications. These findings imply that economic development applies a substantial demand-pull impact on national logistics, i.e., regional economic development directs to the growth of the logistics industry in the corresponding region. Consequently, high-income geographical regions have higher long-run risk concerning contemporary developmental activities of the logistics industry when adhering to carbon emission standards. Particularly, the influence of upcoming emission standards must be prioritized when planning the future returns of contemporary research and development activities of the logistics industry in a given geographic area, such as CPEC. Given Pakistan’s perspective, the proposed empirical analysis can be exampled to other developing countries. This analysis may facilitate the design and development of strategies for upcoming financial funding in the modern logistics industry to seek its sustainable development-goals in developing economies.

Cushing's syndrome is a collection of signs and symptoms due to hypercortisolism. Prolong use of topical steroid may cause this syndrome and suppression of hypothalamic and pituitary function, however such events are more common with oral and parenteral route. There are very few cases of Cushing's syndrome with a topical application amongst which triamcinolone is the rarest drug. We report a case of 11-year-old boy is presented who developed Cushing's disease by topical application. The child had body rashes for which the caregiver consulted a local quack, a topical cream of triamcinolone was prescribed. After application for three months, the patient became obese and developed a moon-like face. A thorough biochemical workup and diagnostic test for Cushing's disease was done to confirm. The following case report a dramatic example of development of the syndrome from chronic topical application of the least potent corticosteroid.