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Your search keyword '"Onco-hematological disease"' showing total 2 results
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2 results on '"Onco-hematological disease"'

1. Transient reactivation of occult hepatitis B virus infection despite lamivudine prophylaxis in a patient treated for non-Hodgkin lymphoma

Author

G. Tonziello, Giuseppe Pasquale, Salvatore Guastafierro, Antonello Sica, Evangelista Sagnelli, Caterina Sagnelli, Marintonietta Pisaturo, Maria Giovanna Ferrara, Nicola Coppola, Tonziello, G., Pisaturo, M., Sica, A., Ferrara, M. G., Sagnelli, C., Pasquale, G., Sagnelli, E., Guastafierro, S., Coppola, N., Tonziello, G, Pisaturo, M, Sica, A, Ferrara, Mg, Sagnelli, Caterina, Pasquale, G, Sagnelli, E, Guastafierro, S, and Coppola, Nicola

Subjects
Occult HBV infection, Microbiology (medical), Hepatitis B virus, medicine.disease_cause, Antiviral Agents, Lamivudine prophylaxi, Immunosuppressive disease, immune system diseases, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aged, 80 and over, Antiviral Agent, Antineoplastic Combined Chemotherapy Protocol, business.industry, Lymphoma, Non-Hodgkin, Lamivudine, Hepatitis B viru, General Medicine, Viral Load, Hepatitis B, medicine.disease, Occult, Lymphoma, Discontinuation, Onco-hematological disease, Infectious Diseases, DNA, Viral, Immunology, Female, Virus Activation, Rituximab, business, Viral load, Human, medicine.drug
Abstract

A female patient with non-Hodgkin lymphoma who tested positive for surface antigen of the hepatitis B virus and negative for hepatitis B core antibody experienced a reactivation of occult HBV infection 20 months after rituximab discontinuation despite lamivudine prophylaxis covering the 4 months of rituximab administration and the subsequent 12 months. © 2012 Springer-Verlag.

Published
2012

2. Reactivation of overt and occult hepatitis B infection in various immunosuppressive settings

Author

Caterina Sagnelli, Evangelista Sagnelli, Salvatore Guastafierro, Maria Stanzione, Messina, G. Tonziello, Mariantonietta Pisaturo, Nicolina Capoluongo, Iodice, Giuseppe Pasquale, Nicola Coppola, Marco Fiore, Coppola, N., Tonziello, G., Pisaturo, M., Messina, V., Guastafierro, S., Fiore, M., Iodice, V., Sagnelli, C., Stanzione, M., Capoluongo, N., Pasquale, G., Sagnelli, E., Coppola, Nicola, Tonziello, G, Pisaturo, M, Messina, V, Guastafierro, Salvatore, Fiore, M, Iodice, V, Sagnelli, Caterina, Stanzione, M, Capoluongo, N, and Pasquale, Giuseppe

Subjects
Occult HBV infection, Adult, Male, Antiviral Agents, Immunosuppressive disease, Immunosuppressive Agent, Antibodies, Monoclonal, Murine-Derived, Immunocompromised Host, Retrospective Studie, Virology, Telbivudine, medicine, Adefovir, Humans, Viremia, HBV infection, Aged, Retrospective Studies, Antiviral Agent, business.industry, Lamivudine, virus diseases, Entecavir, Middle Aged, Viral Load, Hepatitis B, Occult, Survival Analysis, digestive system diseases, Fludarabine, Infectious Diseases, Onco-hematological disease, DNA, Viral, Rituximab, Female, Virus Activation, Survival Analysi, business, Viral load, Immunosuppressive Agents, Vidarabine, medicine.drug, Human
Abstract

The aim of the study was to evaluate clinical and virological differences in HBV reactivation between patients with overt and occult HBV infection. Twenty-three consecutive patients with symptomatic HBV reactivation occurring during or after immunosuppressive therapy were enrolled in a retrospective study: 10 with reactivation of overt HBV infection (overt group) and 13 of occult HBV infection (occult group). Twenty-one patients were treated with nucleot(s)ide analogues after HBV reactivation. Regimens including rituximab or fludarabine were administered more frequently in the occult group (61% vs. 31%, respectively). HBV reactivation was severe frequently in the overt (40%) and occult groups (38.4%). Patients in the overt group showed higher HBV-DNA titers (1.1×10 8±1.4×10 8 vs. 5.1×10 5±6.8×10 5IU; P

Published
2011

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