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5. SURVIVAL AND RECURRENCE OF ENDOCARDITIS FOLLOWING MECHANICAL VS. BIOLOGICAL MITRAL VALVE REPLACEMENT FOR ENDOCARDITIS IN PATIENTS AGED 40 TO 70 YEARS: DATA FROM THE INFECT-REGISTRY

Author

Salsano, A., Di Mauro, M., Labate, L., Della Corte, A., De Bonis, M., Rinaldi, M., Actis Dato, G., Nicolini, F., De Vincentiis, C., Cappabianca, G., Cugola, D., Pacini, D., Vendramin, I., Pilozzi Casado, A., Mikus, E., Onorati, F., Scrofani, R., Musumeci, F., Colli, A., Nicolardi, S., Vizzardi, E., Pantaleo, A., Villa, E., Pollari, F., Barili, F., Parolari, A., Lorusso, R., and Santini, F.

Published
2024
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8. Outcome after Surgery for Type A Aortic Dissection in Patients with Preoperative Invasive Mechanical Ventilation.

Author

Aquila, A. Dell', Wisniewski, K., Georgevici, A. I., Szabó, G., Onorati, F., Rossetti, C., Conradi, L., Demal, T. J., Peterss, S., Buech, J., Fiore, A., Folliguet, T., Perrotti, A., Herve, A., Pinto, A. G., Lega, J. Rodriguez, Pol, M., Mazzaro, E., Gatti, G., and Piani, D.

Subjects
CARDIAC massage, AORTIC dissection, PREHABILITATION, CARDIOGENIC shock, HOSPITAL mortality
Abstract

This article explores the outcomes of surgery for type A aortic dissection in patients who required preoperative invasive mechanical ventilation (IMV). Data from a large European registry showed that 9.26% of patients needed IMV before surgery, with higher mortality rates among IMV patients compared to non-IMV patients. While IMV patients had a higher risk of in-hospital death, their long-term survival after discharge was not significantly different from non-IMV patients. Surgeons may need to adjust surgical strategies for IMV patients to improve immediate outcomes. [Extracted from the article]

Published
2025
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9. Twenty-Minute No-Touch Period Before Controlled DCD Heart Retrieval: Is There Still a Chance for Successful Recovery? The Italian Experience

Author

Gerosa, G., primary, Pradegan, N., additional, Tarzia, V., additional, Lena, T., additional, Zanatta, P., additional, Galeone, A., additional, Gottin, L., additional, Onorati, F., additional, Boffini, M., additional, Zanierato, M., additional, Botta, L., additional, Martin Suarez, S., additional, Feccia, M., additional, Lilla Della Monica, P., additional, Oliveti, A., additional, Pacini, D., additional, Rinaldi, M., additional, Luciani, G.B., additional, and Cardillo, M., additional

Published
2024
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10. Minimally Invasive Mitral Valve Surgery in Elderly Patients: Results from a Multicenter Study

Author

Francica, A, Barbero, C, Tonelli, F, Cerillo, A, Lodo, V, Centofanti, P, Marchetto, G, Di Credico, G, De Paulis, R, Stefano, P, Luciani, G, Onorati, F, Rinaldi, M, Francica, Alessandra, Barbero, Cristina, Tonelli, Filippo, Cerillo, Alfredo Giuseppe, Lodo, Vittoria, Centofanti, Paolo, Marchetto, Giovanni, Di Credico, Germano, De Paulis, Ruggero, Stefano, Pierluigi, Luciani, Giovanni Battista, Onorati, Francesco, Rinaldi, Mauro, Francica, A, Barbero, C, Tonelli, F, Cerillo, A, Lodo, V, Centofanti, P, Marchetto, G, Di Credico, G, De Paulis, R, Stefano, P, Luciani, G, Onorati, F, Rinaldi, M, Francica, Alessandra, Barbero, Cristina, Tonelli, Filippo, Cerillo, Alfredo Giuseppe, Lodo, Vittoria, Centofanti, Paolo, Marchetto, Giovanni, Di Credico, Germano, De Paulis, Ruggero, Stefano, Pierluigi, Luciani, Giovanni Battista, Onorati, Francesco, and Rinaldi, Mauro

Abstract

Background: Minimally invasive mitral valve surgery (MIMVS) has been increasingly adopted worldwide as an alternative to conventional sternotomy, especially for young patients. The remarkable results gained by MIMVS have encouraged its application in more complex and fragile patients, such as the elderly, though results in this subgroup remain controversial. It is the aim of this study to assess the postoperative outcomes of patients older than 75 years old undergoing MIMVS, and to compare these results to those of younger patients. Methods: The data of all patients undergoing MIMVS between 2015 and 2022 were retrospectively collected at seven high-volume cardiac surgery centers. Patients were divided into two age-based groups: the young (<65 years old) and the elderly (>75 years old). A propensity score (PS) matching analysis obtained two comparable groups. Postoperative outcomes were assessed in both the unmatched and PS-matched populations. Results: Out of 1113 patients undergoing MIMVS, 524 were young and 279 were elderly. Elderly patients were more commonly affected by multiple comorbidities, with a higher EuroSCORE II (4.6 ± 5.5% vs. 1.6 ± 3.3%, p < 0.001). There was no difference in postoperative mortality, though the elderly had a greater incidence of postoperative complications, such as re-exploration for bleeding, stroke, reintubation, and a need for hemodialysis and blood transfusions. After PS matching, 119 pairs of young and elderly patients with similar risk profiles (EuroSCORE II 2.5 ± 4.7% vs. 2.7 ± 3.2%, p = 0.7) were compared, and no differences in all postoperative outcomes were found. Conclusions: Adequately selected elderly patients can report hospital outcomes similar to young patients after MIMVS.

Published
2024

13. Malperfusion Syndrome in Patients with Acute Type A Aortic Dissection: Incidence and Mortality Rates after Surgical Repair.

Author

Dell, A. A., Wisniewski, K., Onorati, F., Demal, T.J., Peterss, S., Fiore, A., Perrotti, A., Nappi, F., Pinto, A.G., Pol, M., Mazzaro, E., Vendramin, I., Ferrante, L., Quintana, E., Gerelli, S., Acharya, M., Field, M., Pettinari, M., Stefano, R., and Juvonen, T.

Subjects
AORTIC dissection, DEATH rate, DISSECTION, SYNDROMES, HOSPITAL mortality
Abstract

This article discusses the incidence and mortality rates of malperfusion syndrome in patients with acute Type A aortic dissection after surgical repair. The study, conducted across 18 European centers, included 3,902 patients. It found that 45.62% of patients presented with signs of preoperative malperfusion, with the most common type being cerebral malperfusion. The study also showed that rates of in-hospital mortality increased with the severity of malperfusion. The authors conclude that different levels of the Penn classification can be used as valid predictors of mortality. [Extracted from the article]

Published
2024
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14. Predictor Analysis for Acute Type A Aortic Dissection in Small Aortic Diameters

Author

Demal, T. J., additional, Detter, C., additional, von Kodolitsch, Y., additional, Mariscalco, G., additional, Gatti, G., additional, Peterss, S., additional, Büch, J., additional, Onorati, F., additional, Perrotti, A., additional, Fiore, A., additional, Pettinari, M., additional, Dell'aquila, A. M., additional, Pol, M., additional, Field, M., additional, Vendramin, I., additional, Rinaldi, M., additional, Lega, J. R., additional, Juvonen, T., additional, Quintana, E., additional, Pinto, A. G., additional, Nappi, F., additional, Di Perna, D., additional, Reichenspurner, H., additional, Biancari, F., additional, and Conradi, L., additional

Published
2023
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15. RF44 OUTCOME AFTER BILATERAL INTERNAL MAMMARY ARTERY GRAFTING IN HIGH- AND LOW-VOLUME HOSPITALS: AN ANALYSIS OF THE E-CABG REGISTRY

Author

Saccocci, M., Perotti, A., Reichart, D., Gatti, G., Faggian, G., Onorati, F., Feo, M. De, Chocron, S., Dalen, M., Santarpino, G., Rubino, A.S., Maselli, D., Gherli, R., Salsano, A., Nicolini, F., Zanobini, M., Bounader, K., Seccareccia, F., Rosato, S., Tauriainen, T., Mariscalco, G., Ruggieri, V.G., and Biancari, F.

Published
2018
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18. OC11 CLINICAL FRAILTY SCALE AND OUTCOME AFTER CORONARY ARTERY BYPASS GRAFTING: AN ANALYSIS OF THE E-CABG REGISTRY

Author

Saccocci, M., Reichart, D., Rosato, S., Nammas, W., Onorati, F., Dalen, M., Castro, L., Gherli, R., Gatti, G., Franzese, I., Faggian, G., De Feo, M., Khodabandeh, S., Santarpino, G., Rubino, A.S., Maselli, D., Nardella, S., Salsano, A., Nicolini, F., Zanobini, M., Bounader, K., Kinnunen, E., Tauriainen, T., Airaksinen, J., Seccareccia, F., Mariscalco, G., Ruggieri, V.G., Perrotti, A., and Biancari, F.

Published
2018
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19. OC87 VALUE OF SCREENING ASYMPTOMATIC CAROTID ARTERY STENOSIS PRIOR TO CORONARY ARTERY BYPASS GRAFTING: ANALYSIS OF THE E-CABG REGISTRY

Author

Salsano, A., Santarpino, G., Santini, F., Nicolini, F., De Feo, M., Dalén, M., Fischlein, T., Perrotti, A., Reichart, D., Gatti, G., Onorati, F., Franzese, I., Faggian, G., Bancone, C., Chocron, S., Khodabandeh, S., Rubino, A.S., Maselli, D., Nardella, S., Gherli, R., Zanobini, M., Saccocci, M., Bounader, K., Rosato, S., Tauriainen, T., Mariscalco, G., Airaksinen, J., Ruggieri, V.G., and Biancari, F.

Published
2018
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20. OC88 COMPARATIVE ANALYSIS OF PROTHROMBIN COMPLEX CONCENTRATE AND FRESH FROZEN PLASMA IN THE MANAGEMENT OF PERIOPERATIVE BLEEDING AFTER CORONARY ARTERY BYPASS GRAFTING

Author

Salsano, A., Mariscalco, G., Santini, F., Ruggieri, V.G., Perrotti, A., Chocron, S., Gherli, R., Reichart, D., Demal, T., Faggian, G., Franzese, I., Dalén, M., Santarpino, G., Fischlein, T., Rubino, A.S., Maselli, D., Nardella, S., Nicolini, F., Saccocci, M., Gatti, G., Bounader, K., Rosato, S., Kinnunen, E., De Feo, M., Tauriainen, T., Onorati, F., and Biancari, F.

Published
2018
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22. OC71 SURGICAL TREATMENT FOR ISOLATED TRICUSPID VALVE INFECTIVE ENDOCARDITIS. 25-YEAR RESULTS

Author

Di Mauro, M., Dato, G. Actis, Barili, F., Corte, A. Della, Ratta, E. Della, Cugola, D., Galletti, L., Centofanti, P., Santini, F., Salsano, A., Rinaldi, M., Mancuso, S., Cappabianca, G., Beghi, C., De Vincentiis, C., Biondi, A., Livi, U., Sponga, S., Pacini, D., Murara, G., Di Bortalomeo, R., Scrofani, R., Cagnoni, G., Antona, C., Nicolini, F., Benassi, F., De Bonis, M., Pozzoli, A., Casali, G., Scrascia, G., Bortolotti, U., Falcetta, G., Musumeci, F., Gherli, R., Vizzardi, E., Salvador, L., Piccichè, M., Paparella, D., Margari, V., Troise, G., Villa, E., Dossena, Y., Lucarelli, C., Onorati, F., Faggian, G., Mariscalco, G., Maselli, D., Foschi, M., Parolari, A., and Lorusso, R.

Published
2018
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24. COVID-19 in Heart Transplant Recipients: A Multicenter Analysis of the Northern Italian Outbreak

Author

Bottio, T, Bagozzi, L, Fiocco, A, Nadali, M, Caraffa, R, Bifulco, O, Ponzoni, M, Lombardi, C, Metra, M, Russo, C, Frigerio, M, Masciocco, G, Potena, L, Loforte, A, Pacini, D, Faggian, G, Onorati, F, Sponga, S, Livi, U, Iacovoni, A, Terzi, A, Senni, M, Rinaldi, M, Boffini, M, Marro, M, Jorgji, V, Carrozzini, M, Gerosa, G, Bottio T, Bagozzi L, Fiocco A, Nadali M, Caraffa R, Bifulco O, Ponzoni M, Lombardi CM, Metra M, Russo CF, Frigerio M, Masciocco G, Potena L, Loforte A, Pacini D, Faggian G, Onorati F, Sponga S, Livi U, Iacovoni A, Terzi A, Senni M, Rinaldi M, Boffini M, Marro M, Jorgji V, Carrozzini M, Gerosa G, Bottio, T, Bagozzi, L, Fiocco, A, Nadali, M, Caraffa, R, Bifulco, O, Ponzoni, M, Lombardi, C, Metra, M, Russo, C, Frigerio, M, Masciocco, G, Potena, L, Loforte, A, Pacini, D, Faggian, G, Onorati, F, Sponga, S, Livi, U, Iacovoni, A, Terzi, A, Senni, M, Rinaldi, M, Boffini, M, Marro, M, Jorgji, V, Carrozzini, M, Gerosa, G, Bottio T, Bagozzi L, Fiocco A, Nadali M, Caraffa R, Bifulco O, Ponzoni M, Lombardi CM, Metra M, Russo CF, Frigerio M, Masciocco G, Potena L, Loforte A, Pacini D, Faggian G, Onorati F, Sponga S, Livi U, Iacovoni A, Terzi A, Senni M, Rinaldi M, Boffini M, Marro M, Jorgji V, Carrozzini M, and Gerosa G

Abstract

Objectives: The aim of this study was to assess the clinical course and outcomes of all heart transplant recipients affected by coronavirus disease-2019 (COVID-19) who were followed at the leading heart transplant centers of Northern Italy. Background: The worldwide severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has created unprecedented challenges for public health, demanding exceptional efforts for the successful management and treatment of affected patients. Heart transplant patients represent a unique cohort of chronically immunosuppressed subjects in which SARS-CoV-2 may stimulate an unpredictable clinical course of infection. Methods: Since February 2020, we enrolled all 47 cases (79% male) in a first cohort of patients, with a mean age of 61.8 ± 14.5 years, who tested positive for SARS-CoV-2, out of 2,676 heart transplant recipients alive before the onset of the COVID-19 pandemic at 7 heart transplant centers in Northern Italy. Results: To date, 38 patients required hospitalization while 9 remained self-home quarantined and 14 died. Compared to the general population, prevalence (18 vs. 7 cases per 1,000) and related case fatality rate (29.7% vs. 15.4%) in heart transplant recipients were doubled. Univariable analysis showed older age (p = 0.002), diabetes mellitus (p = 0.040), extracardiac arteriopathy (p = 0.040), previous PCI (p = 0.040), CAV score (p = 0.039), lower GFR (p = 0.004), and higher NYHA functional classes (p = 0.023) were all significantly associated with in-hospital mortality. During the follow-up two patients died and a third patient has prolonged viral-shedding alternating positive and negative swabs. Since July 1st, 2020, we had 6 new patients who tested positive for SARS-CoV-2, 5 patients asymptomatic were self-quarantined, while 1 is still hospitalized for pneumonia. A standard therapy was maintained for all, except for the hospitalized patient. Conclusions: The prevalence and mortality of SARS-CoV-2 should spur cl

Published
2021

26. COVID-19 in Heart Transplant Recipients: A Multicenter Analysis of the Northern Italian Outbreak

Author

Bottio T, Bagozzi L, Fiocco A, Nadali M, Caraffa R, Bifulco O, Ponzoni M, Lombardi CM, Metra M, Russo CF, Frigerio M, Masciocco G, Potena L, Loforte A, Pacini D, Faggian G, Onorati F, Sponga S, Livi U, Iacovoni A, Terzi A, Senni M, Rinaldi M, Boffini M, Marro M, Jorgji V, Carrozzini M, Gerosa G, Bottio T., Bagozzi L., Fiocco A., Nadali M., Caraffa R., Bifulco O., Ponzoni M., Lombardi C.M., Metra M., Russo C.F., Frigerio M., Masciocco G., Potena L., Loforte A., Pacini D., Faggian G., Onorati F., Sponga S., Livi U., Iacovoni A., Terzi A., Senni M., Rinaldi M., Boffini M., Marro M., Jorgji V., Carrozzini M., Gerosa G., Bottio, T, Bagozzi, L, Fiocco, A, Nadali, M, Caraffa, R, Bifulco, O, Ponzoni, M, Lombardi, C, Metra, M, Russo, C, Frigerio, M, Masciocco, G, Potena, L, Loforte, A, Pacini, D, Faggian, G, Onorati, F, Sponga, S, Livi, U, Iacovoni, A, Terzi, A, Senni, M, Rinaldi, M, Boffini, M, Marro, M, Jorgji, V, Carrozzini, M, and Gerosa, G

Subjects
Male, COVID-19 and heart transplant recipient, TAPSE, Tricuspid annular plane systolic excursion, immunosuppressive therapy, COPD, Chronic obstructive pulmonary disease, BMI, Body mass index, Comorbidity, heart transplantation, Article, COVID-19 and heart transplant recipients, Follow-Up Studie, ECLS, Extracorporeal life support, SARS-CoV-2, Severe Acute Respiratory Syndrome-Coronavirus-2, Retrospective Studie, ICU, Intensive Care Unit, ARDS, Acute respiratory distress syndrome, Humans, COVID-19, Coronavirus Disease 19, sPAP, Systolic pulmonary artery pressure, PCI, Percutaneous coronary intervention, Hospital Mortality, NYHA, New York Heart Association, Pandemics, Aged, Retrospective Studies, RT-PCR, Reverse transcriptase-polymerase chain reaction, Heart Failure, Pandemic, SARS-CoV-2, ALT, Alanine aminotransferase, COVID-19, Female, Follow-Up Studies, Italy, Middle Aged, Heart Transplantation, Transplant Recipients, CAV, Cardiac allograft vasculopathy, GFR, Glomerular filtration rate, CRP, C-reactive Protein, WBC, White blood cells, LVEF, Left ventricular ejection fraction, PCT, Procalcitonin, iLVEDV, Indexed left ventricular end-diastolic volume, AST, Aspartate aminotransferase, Human
Abstract

Aims The aim of this study was to assess the clinical course and outcomes of all heart transplant recipients affected by COVID-19 who were followed at the leading heart transplant centers of Northern Italy. Method and Results Since February 2020, we enrolled all 47 cases (79% male) in a first cohort of patients, with a mean age of 61.8 ± 14.5 years, who tested positive for SARS-CoV-2, out of 2676 heart transplant recipients alive before the onset of the COVID-19 pandemic at 7 heart transplant centers in Northern Italy. To date, 38 patients required hospitalization while 9 remained self-home quarantined and 14 died. Compared to the general population, prevalence (18 vs 7 cases per 1000) and related case fatality rate (29.7 vs 15.4%) in heart transplant recipients were doubled. Univariable analysis showed older age (p=0.002), diabetes mellitus (p=0.040), extracardiac arteriopathy (p=0.040), previous PCI (p=0.040), CAV score (p=0.039), lower GFR (p=0.004), and higher NYHA classes (p=0.023) were all significantly associated with in-hospital mortality. During the follow-up two patients died and a third patient has prolonged viral-shedding alternating positive and negative swabs. Since 1st July 2020, we had 6 new patients who tested positive for SARS-CoV-2, 5 patients asymptomatic were self-quarantined, while 1 is still hospitalized for pneumonia. A standard therapy was maintained for all, except for the hospitalized patient. Conclusion The prevalence and mortality of SARS-CoV-2 should spur clinicians to immediately refer heart transplant recipients suspected as having SARS-CoV2 infection to centers specializing in the care of this vulnerable population., Graphical abstract

Published
2021

28. Late myocardial infarction and repeat revascularization after coronary artery bypass grafting in patients with prior percutaneous coronary intervention

Author

Biancari, F. (Fausto), Salsano, A. (Antonio), Santini, F. (Francesco), De Feo, M. (Marisa), Dalén, M. (Magnus), Zhang, Q. (Qiyao), Gatti, G. (Giuseppe), Mazzaro, E. (Enzo), Franzese, I. (Ilaria), Bancone, C. (Ciro), Zanobini, M. (Marco), Tauriainen, T. (Tuomas), Mäkikallio, T. (Timo), Saccocci, M. (Matteo), Francica, A. (Alessandra), Rosato, S. (Stefano), El-Dean, Z. (Zein), Onorati, F. (Francesco), Mariscalco, G. (Giovanni), Biancari, F. (Fausto), Salsano, A. (Antonio), Santini, F. (Francesco), De Feo, M. (Marisa), Dalén, M. (Magnus), Zhang, Q. (Qiyao), Gatti, G. (Giuseppe), Mazzaro, E. (Enzo), Franzese, I. (Ilaria), Bancone, C. (Ciro), Zanobini, M. (Marco), Tauriainen, T. (Tuomas), Mäkikallio, T. (Timo), Saccocci, M. (Matteo), Francica, A. (Alessandra), Rosato, S. (Stefano), El-Dean, Z. (Zein), Onorati, F. (Francesco), and Mariscalco, G. (Giovanni)

Abstract

Objectives: The aim of the present study was to evaluate the risk of late mortality and major adverse cardiovascular and cerebral events after coronary artery bypass grafting (CABG) in patients with prior percutaneous coronary intervention (PCI). Methods: A total of 2948 patients undergoing isolated CABGs were included in a prospective multicenter registry. Outcomes were adjusted for multiple covariates in logistic regression, Cox proportional hazards analysis and competing risk analysis. Results: In all, 2619 patients fulfilled the inclusion criteria of this analysis. Of them, 2199 (79.1%) had no history of PCI and 420 (20.9%) had a prior PCI. An adjusted analysis showed that a single prior PCI and multiple prior PCIs did not increase the risk of 30-day and 5-year mortality. Patients with multiple prior PCIs had a significantly higher risk of 5-year myocardial infarction (SHR 2.566, 95%CI 1.379–4.312) and repeat revascularization (SHR 1.774, 95%CI 1.140–2.763). Similarly, 30-day and 5-year mortality were not significantly increased in patients with prior PCI treatment of single or multiple vessels. Patients with multiple vessels treated with PCI had a significantly higher risk of 5-year myocardial infarction (SHR 2.640, 95%CI 1.497–4.658), repeat revascularization (SHR 1.648, 95%CI 1.029–2.638) and stroke (SHR 2.215, 95%CI 1.056–4.646) at 5-year. The risk for repeat revascularization was also increased with a prior single vessel PCI, but not for other outcomes. Conclusions: Among patients undergoing CABGs, multiple prior PCIs seem to increase the risk of late myocardial infarction and the need for repeat revascularization, but not the risk of mortality.

Published
2022

29. Multicenter Italian Study on Radial Mechanically Assisted Circulatory Support (MIRAMACS): Ongoing Analyses

Author

Loforte, A., primary, Gliozzi, G., additional, Attisani, M., additional, Comisso, M., additional, Iacovoni, A., additional, Maiani, M., additional, Boschi, S., additional, Onorati, F., additional, Scandroglio, M., additional, Baronetto, A., additional, Terzi, A., additional, De Bonis, M., additional, Santini, F., additional, Faggian, G., additional, Livi, U., additional, Musumeci, F., additional, Rinaldi, M., additional, and Pacini, D., additional

Published
2022
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35. Surgical treatment of isolated tricuspid valve infective endocarditis: 25-year results from a multicenter registry

Author

Di Mauro, M, Foschi, M, Dato, G, Centofanti, P, Barili, F, Corte, A, Ratta, E, Cugola, D, Galletti, L, Santini, F, Salsano, A, Rinaldi, M, Mancuso, S, Cappabianca, G, Beghi, C, De Vincentiis, C, Biondi, A, Livi, U, Sponga, S, Pacini, D, Murana, G, Scrofani, R, Antona, C, Cagnoni, G, Nicolini, F, Benassi, F, De Bonis, M, Pozzoli, A, Casali, G, Scrascia, G, Falcetta, G, Bortolotti, U, Musumeci, F, Gherli, R, Vizzardi, E, Salvador, L, Piciche, M, Paparella, D, Margari, V, Troise, G, Villa, E, Dossena, Y, Lucarelli, C, Onorati, F, Faggian, G, Mariscalco, G, Maselli, D, Parolari, A, Lorusso, R, Di Mauro M., Foschi M., Dato G. M. A., Centofanti P., Barili F., Corte A. D., Ratta E. D., Cugola D., Galletti L., Santini F., Salsano A., Rinaldi M., Mancuso S., Cappabianca G., Beghi C., De Vincentiis C., Biondi A., Livi U., Sponga S., Pacini D., Murana G., Scrofani R., Antona C., Cagnoni G., Nicolini F., Benassi F., De Bonis M., Pozzoli A., Casali G., Scrascia G., Falcetta G., Bortolotti U., Musumeci F., Gherli R., Vizzardi E., Salvador L., Piciche M., Paparella D., Margari V., Troise G., Villa E., Dossena Y., Lucarelli C., Onorati F., Faggian G., Mariscalco G., Maselli D., Parolari A., Lorusso R., Di Mauro, M, Foschi, M, Dato, G, Centofanti, P, Barili, F, Corte, A, Ratta, E, Cugola, D, Galletti, L, Santini, F, Salsano, A, Rinaldi, M, Mancuso, S, Cappabianca, G, Beghi, C, De Vincentiis, C, Biondi, A, Livi, U, Sponga, S, Pacini, D, Murana, G, Scrofani, R, Antona, C, Cagnoni, G, Nicolini, F, Benassi, F, De Bonis, M, Pozzoli, A, Casali, G, Scrascia, G, Falcetta, G, Bortolotti, U, Musumeci, F, Gherli, R, Vizzardi, E, Salvador, L, Piciche, M, Paparella, D, Margari, V, Troise, G, Villa, E, Dossena, Y, Lucarelli, C, Onorati, F, Faggian, G, Mariscalco, G, Maselli, D, Parolari, A, Lorusso, R, Di Mauro M., Foschi M., Dato G. M. A., Centofanti P., Barili F., Corte A. D., Ratta E. D., Cugola D., Galletti L., Santini F., Salsano A., Rinaldi M., Mancuso S., Cappabianca G., Beghi C., De Vincentiis C., Biondi A., Livi U., Sponga S., Pacini D., Murana G., Scrofani R., Antona C., Cagnoni G., Nicolini F., Benassi F., De Bonis M., Pozzoli A., Casali G., Scrascia G., Falcetta G., Bortolotti U., Musumeci F., Gherli R., Vizzardi E., Salvador L., Piciche M., Paparella D., Margari V., Troise G., Villa E., Dossena Y., Lucarelli C., Onorati F., Faggian G., Mariscalco G., Maselli D., Parolari A., and Lorusso R.

Abstract

Background: To assess early and late mortality in patients with isolated acute tricuspid valve infective endocarditis (TVIE) using data from a multicenter registry. Methods: From 1983 to 2018, isolated acute TVIE was surgically treated in 157 (3.8%) patients [mean age 47 ± 16 years (range 15–86 years), 25% females]. Of these, 142 (90%) had native tricuspid regurgitation, 7 (5%) native tricuspid valve (TV) steno-regurgitation, and 8 (5%) prosthetic TVIE. Intravenous drug use (IVDU) was recorded in 38% of patients, infection involved cardiac implantable electronic device leads in 21%, and vascular catheters for dialysis in 1%; in the remaining cases, the cause was unknown. The primary endpoint was in-hospital outcome, long-term freedom from recurrence and overall survival. Results: Overall, 77 (49%) patients underwent TV repair, 72 (46%) TV replacement, and 8 (5%) prosthetic TV replacement. Early mortality was 11% (n = 17). Expected early mortality according to EndoSCORE was 12%, with age (odds ratio 1.06) and redo (odds ratio 6.64) as risk factors. Late deaths occurred in 31 patients and TVIE recurrences in 4. Survival rates at 10, 20, and 25 years were 66%, 60%, and 44%, respectively. Risk factors were age [hazard ratio (HR) 1.06], mycotic TVIE (HR 4.2), IVDU (HR 4.90), infected prosthesis replacement (HR 4.4), and presence of cardiac implantable electronic device leads (HR 3.0). No significant difference was found in valve repair vs. replacement and in IVDUs vs. non-IVDUs. Conclusions: Patients with isolated acute TVIE undergoing surgical treatment show acceptable early and late outcomes. TVIE recurrence was low, and repair of the affected valve does not seem to confer any advantage either at early or long term up to 25 years.

Published
2019

36. Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria (Journal of Cardiothoracic Surgery, (2021), 16, 1, (171), 10.1186/s13019-021-01536-5)

Author

Biancari, F., Mariscalco, G., Yusuff, H., Tsang, G., Luthra, S., Onorati, F., Francica, A., Rossetti, C., Perrotti, A., Chocron, S., Fiore, A., Folliguet, T., Pettinari, M., Dell'Aquila, A. M., Demal, T., Conradi, L., Detter, C., Pol, M., Ivak, P., Schlosser, F., Forlani, S., Chetty, G., Harky, A., Kuduvalli, M., Field, M., Vendramin, I., Livi, U., Rinaldi, M., Ferrante, L., Etz, C., Noack, T., Mastrobuoni, S., De Kerchove, L., Jormalainen, M., Laga, S., Meuris, B., Schepens, M., Dean, Z. E., Vento, A., Raivio, P., Borger, M., and Juvonen, T.

Published
2021

38. European registry of type A aortic dissection (ERTAAD):rationale, design and definition criteria

Author

Biancari, F. (Fausto), Mariscalco, G. (Giovanni), Yusuff, H. (Hakeem), Tsang, G. (Geoffrey), Luthra, S. (Suvitesh), Onorati, F. (Francesco), Francica, A. (Alessandra), Rossetti, C. (Cecilia), Perrotti, A. (Andrea), Chocron, S. (Sidney), Fiore, A. (Antonio), Folliguet, T. (Thierry), Pettinari, M. (Matteo), Dell’Aquila, A. M. (Angelo M.), Demal, T. (Till), Conradiv, L. (Lenard), Detter, C. (Christian), Pol, M. (Marek), Ivak, P. (Peter), Schlosser, F. (Filip), Forlani, S. (Stefano), Chetty, G. (Govind), Harky, A. (Amer), Kuduvalli, M. (Manoj), Field, M. (Mark), Vendramin, I. (Igor), Livi, U. (Ugolino), Rinaldi, M. (Mauro), Ferrante, L. (Luisa), Etz, C. (Christian), Noack, T. (Thilo), Mastrobuoni, S. (Stefano), De Kerchove, L. (Laurent), Jormalainen, M. (Mikko), Laga, S. (Steven), Meuris, B. (Bart), Schepens, M. (Marc), El Dean, Z. (Zein), Vento, A. (Antti), Raivio, P. (Peter), Borger, M. (Michael), Juvonen, T. (Tatu), Biancari, F. (Fausto), Mariscalco, G. (Giovanni), Yusuff, H. (Hakeem), Tsang, G. (Geoffrey), Luthra, S. (Suvitesh), Onorati, F. (Francesco), Francica, A. (Alessandra), Rossetti, C. (Cecilia), Perrotti, A. (Andrea), Chocron, S. (Sidney), Fiore, A. (Antonio), Folliguet, T. (Thierry), Pettinari, M. (Matteo), Dell’Aquila, A. M. (Angelo M.), Demal, T. (Till), Conradiv, L. (Lenard), Detter, C. (Christian), Pol, M. (Marek), Ivak, P. (Peter), Schlosser, F. (Filip), Forlani, S. (Stefano), Chetty, G. (Govind), Harky, A. (Amer), Kuduvalli, M. (Manoj), Field, M. (Mark), Vendramin, I. (Igor), Livi, U. (Ugolino), Rinaldi, M. (Mauro), Ferrante, L. (Luisa), Etz, C. (Christian), Noack, T. (Thilo), Mastrobuoni, S. (Stefano), De Kerchove, L. (Laurent), Jormalainen, M. (Mikko), Laga, S. (Steven), Meuris, B. (Bart), Schepens, M. (Marc), El Dean, Z. (Zein), Vento, A. (Antti), Raivio, P. (Peter), Borger, M. (Michael), and Juvonen, T. (Tatu)

Abstract

Background: Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient’s conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD. Methods: Nineteen centers of cardiac surgery from seven European countries have collaborated to create a multicentre observational registry (ERTAAD), which will enroll consecutive patients who underwent surgery for acute TAAD from January 2005 to March 2021. Analysis of the impact of patient’s comorbidities, conditions at referral, surgical strategies and perioperative treatment on the early and late adverse events will be performed. The investigators have developed a classification of the urgency of the procedure based on the severity of preoperative hemodynamic conditions and malperfusion secondary to acute TAAD. The primary clinical outcomes will be in-hospital mortality, late mortality and reoperations on the aorta. Secondary outcomes will be stroke, acute kidney injury, surgical site infection, reoperation for bleeding, blood transfusion and length of stay in the intensive care unit. Discussion: The analysis of this multicentre registry will allow conclusive results on the prognostic importance of critical preoperative conditions and the value of different treatment strategies to reduce the risk of early adverse events after surgery for acute TAAD. This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. Trial registration: ClinicalTrials.gov Identifier: NCT04831073.

Published
2021

40. Multicenter Italian Study on Radial Mechanically Assisted Circulatory Support (MIRAMACS): Preliminary Results

Author

Loforte, A., primary, Gliozzi, G., additional, Attisani, M., additional, Montalto, A., additional, Iacovoni, A., additional, Onorati, F., additional, Maiani, M., additional, Scandroglio, M., additional, Terzi, A., additional, De Bonis, M., additional, Faggian, G., additional, Livi, U., additional, Musumeci, F., additional, Rinaldi, M., additional, and Pacini, D., additional

Published
2021
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42. Infectious complications in patients receiving ticagrelor or clopidogrel before coronary artery bypass grafting

Author

Perrotti, A., Mariscalco, G., Onorati, F., Faggian, G., Franzese, I., Salsano, A., Santini, F., Ruggieri, V.G., Maselli, D., Nardella, S., Santarpino, G., Fischlein, T., Saccocci, M., Zanobini, M., Musumeci, F., Gherli, R., Rubino, A.S., De Feo, M., Bancone, C., Nicolini, F., Kinnunen, E.-M., Tauriainen, T., Reichart, D., Demal, T., Gatti, G., Khodabandeh, S., Holm, M., Dalén, M., and Biancari, F.

Published
2020
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44. Impact of Aortic Manipulation on High Perioperative Cerebral Stroke Risk Undergoing Coronary Artery Bypass Grafting: Results from the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting)

Author

Naito, S., additional, Demal, T. J., additional, Schneeberger, Y., additional, Reichenspurner, H., additional, Gatti, G., additional, Onorati, F., additional, Mariscalco, G., additional, Santini, F., additional, Sill, B., additional, and Biancari, F., additional

Published
2021
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45. On-Pump versus Off-Pump Coronary Bypass Grafting in Patients with Non–Dialysis-Dependent Renal Impairment

Author

Hua, X., additional, Demal, T. J., additional, Reiter, B., additional, Dalén, M., additional, Ruggieri, V. G., additional, Gatti, G., additional, Onorati, F., additional, Rubino, A. S., additional, Maselli, D., additional, Gherli, R., additional, Salsano, A., additional, Saccocci, M., additional, Santarpino, G., additional, Nicolini, F., additional, De Feo, M., additional, Perrotti, A., additional, Mariscalco, G., additional, Reichenspurner, H., additional, and Biancari, F., additional

Published
2021
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50. Corrigendum to “A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE”. [Int. J. Cardiol. 241 (Aug 15 2017) 97–102](S0167527317309877)(10.1016/j.ijcard.2017.03.148)

Author

Di Mauro M., Di Mauro, M, Dato, G, Barili, F, Gelsomino, S, Sante, P, Corte, A, Carrozza, A, Ratta, E, Cugola, D, Galletti, L, Devotini, R, Casabona, R, Santini, F, Salsano, A, Scrofani, R, Antona, C, Botta, L, Russo, C, Mancuso, S, Rinaldi, M, De Vincentiis, C, Biondi, A, Beghi, C, Cappabianca, G, Tarzia, V, Gerosa, G, De Bonis, M, Pozzoli, A, Nicolini, F, Benassi, F, Rosato, F, Grasso, E, Livi, U, Sponga, S, Pacini, D, Di Bartolomeo, R, Demartino, A, Bortolotti, U, Onorati, F, Faggian, G, Lorusso, R, Vizzardi, E, Di Giammarco, G, Marinelli, D, Villa, E, Troise, G, Piciche, M, Musumeci, F, Paparella, D, Margari, V, Tritto, F, Damiani, G, Scrascia, G, Zaccaria, S, Renzulli, A, Serraino, G, Mariscalco, G, Maselli, D, Foschi, M, Parolari, A, Nappi, G, Di Mauro M., Dato G. M. A., Barili F., Gelsomino S., Sante P., Corte A. D., Carrozza A., Ratta E. D., Cugola D., Galletti L., Devotini R., Casabona R., Santini F., Salsano A., Scrofani R., Antona C., Botta L., Russo C., Mancuso S., Rinaldi M., De Vincentiis C., Biondi A., Beghi C., Cappabianca G., Tarzia V., Gerosa G., De Bonis M., Pozzoli A., Nicolini F., Benassi F., Rosato F., Grasso E., Livi U., Sponga S., Pacini D., Di Bartolomeo R., DeMartino A., Bortolotti U., Onorati F., Faggian G., Lorusso R., Vizzardi E., Di Giammarco G., Marinelli D., Villa E., Troise G., Piciche M., Musumeci F., Paparella D., Margari V., Tritto F., Damiani G., Scrascia G., Zaccaria S., Renzulli A., Serraino G., Mariscalco G., Maselli D., Foschi M., Parolari A., Nappi G., Di Mauro M., Di Mauro, M, Dato, G, Barili, F, Gelsomino, S, Sante, P, Corte, A, Carrozza, A, Ratta, E, Cugola, D, Galletti, L, Devotini, R, Casabona, R, Santini, F, Salsano, A, Scrofani, R, Antona, C, Botta, L, Russo, C, Mancuso, S, Rinaldi, M, De Vincentiis, C, Biondi, A, Beghi, C, Cappabianca, G, Tarzia, V, Gerosa, G, De Bonis, M, Pozzoli, A, Nicolini, F, Benassi, F, Rosato, F, Grasso, E, Livi, U, Sponga, S, Pacini, D, Di Bartolomeo, R, Demartino, A, Bortolotti, U, Onorati, F, Faggian, G, Lorusso, R, Vizzardi, E, Di Giammarco, G, Marinelli, D, Villa, E, Troise, G, Piciche, M, Musumeci, F, Paparella, D, Margari, V, Tritto, F, Damiani, G, Scrascia, G, Zaccaria, S, Renzulli, A, Serraino, G, Mariscalco, G, Maselli, D, Foschi, M, Parolari, A, Nappi, G, Di Mauro M., Dato G. M. A., Barili F., Gelsomino S., Sante P., Corte A. D., Carrozza A., Ratta E. D., Cugola D., Galletti L., Devotini R., Casabona R., Santini F., Salsano A., Scrofani R., Antona C., Botta L., Russo C., Mancuso S., Rinaldi M., De Vincentiis C., Biondi A., Beghi C., Cappabianca G., Tarzia V., Gerosa G., De Bonis M., Pozzoli A., Nicolini F., Benassi F., Rosato F., Grasso E., Livi U., Sponga S., Pacini D., Di Bartolomeo R., DeMartino A., Bortolotti U., Onorati F., Faggian G., Lorusso R., Vizzardi E., Di Giammarco G., Marinelli D., Villa E., Troise G., Piciche M., Musumeci F., Paparella D., Margari V., Tritto F., Damiani G., Scrascia G., Zaccaria S., Renzulli A., Serraino G., Mariscalco G., Maselli D., Foschi M., Parolari A., and Nappi G.

Abstract

The authors regret that the first name and last name of the author Sandro Sponga was published incorrectly in the original version and this has now been corrected.

Published
2018

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