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Intraplate earthquakes induced by anthropogenic fluid injection present unexpected seismic risk to previously quiescent or low seismicity-rate regions. Despite many studies of induced seismicity, there are relatively few with detailed openly accessible constraints on the interaction between seismic sources and subsurface structures. In this study of the Raton Basin, we refine source observations from a dense nodal array and constrain basin structure using teleseismic receiver functions. The cross-correlation-based relocated hypocentres and a new set of focal mechanisms light up active fault segments and show clear spatiotemporal patterns. The geometric complexity of reactivated fault clusters appears greatest near higher rate injection wells. Simpler normal fault structure is found farther from injection wells and near abrupt structural transitions suggested by receiver functions. While less induced seismicity in the crystalline basement is expected when injection is >1 km from the top of the basement (like Raton), our receiver function analysis identified a basin thickness ~3 km beneath the nodal array and lateral variations in sedimentary structures. Our results explain potential fluid connectivity between the injection depths focused at ~1–1.5 km below the surface and basement fault activity that begins at ~3 km and reaches peak activity at ~4–8 km depths. This article is part of the theme issue 'Induced seismicity in coupled subsurface systems'. [ABSTRACT FROM AUTHOR]

We examine the coseismic influence of the 5 July 2019, MW7.1 Ridgecrest and the 24 June 2020 MW5.8 Owens Lake earthquakes on rockfall distributions in two undisturbed high-altitude areas of the southern Sierra Nevada Mountains, California, USA. These events occurred within the geologically recent (<2 Mya) Walker Lane/eastern California shear zone. While both study areas are characterized as plutonic, the Owens Lake event largely affected terrain that was formerly glaciated and oversteepened while the Ridgecrest event affected non-glaciated terrain. Our inventory of rockfall locations was derived from analysis of Sentinel-2 images acquired just prior to and immediately after the events. This difference mapping approach using readily-available Sentinel-2 imagery allows for rapid rockfall and landslide mapping. GIS analysis shows that even though the total area assessed for both earthquakes was similar (~1500 km2), the significantly lower magnitude Owens Lake event produced nearly twice as many (102) mappable rockslides as the significantly stronger Ridgecrest event (58), a difference likely due to slope oversteepening in the formerly glaciated area. Significant seismic amplification by topography and reactivation of preexisting failures was apparent for both areas. Inclusion of these factors may improve failure predictions and rockfall probability estimation. [ABSTRACT FROM AUTHOR]

We conduct a high‐resolution teleseismic receiver function investigation of the subducting plate interface within the Alaskan forearc beneath Kodiak Island using data collected as part of the Alaska Amphibious Community Seismic Experiment in 2019. The Kodiak node array consisted of 398 nodal geophones deployed at ∼200–300 m spacing on northeastern Kodiak Island within the southern asperity of the 1964 Mw9.2 Great Alaska earthquake. Receiver function images at frequencies of 1.2 and 2.4 Hz show a coherent, slightly dipping velocity increase at ∼30–40 km depth consistent with the expected slab Moho. In contrast to studies within the northern asperity of the 1964 rupture, we find no evidence for a prominent low‐velocity layer above the slab Moho thick enough to be resolved by upgoing P‐to‐S conversions. These results support evidence from seismicity and geodetic strain suggesting that the 1964 rupture connected northern (Kenai) and southern (Kodiak) asperities with different plate interface properties. Plain Language Summary: We use 398 portable seismometers that were deployed as part of the Alaska Amphibious Community Seismic Experiment to image the boundary between the subducting Pacific plate and the base of the North American plate. The seismometers, spaced ∼200–300 m apart, were stationed on Kodiak Island in 2019 within the southern rupture area of the 1964 Mw9.2 Great Alaska earthquake. We analyze conversions from compressional to shear waves from distant earthquakes to understand the conditions of the plate interface. Our results show a dipping velocity increase at ∼30–40 km depth at the expected location of the Pacific slab crust‐mantle boundary. In contrast to prior results from the northern 1964 rupture zone, we do not find a low‐velocity layer on the subducting plate. Our results indicate that the 1964 rupture connected segments of the Alaskan subduction zone with different plate interface properties. Key Points: We present receiver function imaging from a dense three‐component nodal array deployment on Kodiak Island above the subducting Pacific PlateA clear slab Moho conversion is found but, in contrast to the Kenai Peninsula, there is no coherent low‐velocity layer atop the slabThe 1964 Great Alaska Earthquake ruptured across structural segments with different plate interface properties [ABSTRACT FROM AUTHOR]

The complex postdetonation geologic structures that form after an underground nuclear explosion are hard to constrain because increased heterogeneity around the damage zone affects seismic waves that propagate through the explosion site. Generally, a vertical rubble‐filled structure known as a chimney is formed after an underground nuclear explosion that is composed of debris that falls into the subsurface cavity generated by the explosion. Compared with chimneys that collapse fully, leaving a surface crater, partially collapsed chimneys can have remnant subsurface cavities left in place above collapsed rubble. The 1964 nuclear test HADDOCK, conducted at the Nevada test site (now the Nevada National Security Site), formed a partially collapsed chimney with no surface crater. Understanding the subsurface structure of these features has significant national security applications, such as aiding the study of suspected underground nuclear explosions under a treaty verification. In this study, we investigated the subsurface architecture of the HADDOCK legacy nuclear test using hybrid 2D-3D active source seismic reflection and refraction data. The seismic data were acquired using 275 survey shots from the Seismic Hammer (a 13,000 kg weight drop) and 65 survey shots from a smaller accelerated weight drop, both recorded by ∼1000 three‐component 5 Hz geophones. First‐arrival, P‐wave tomographic modeling shows a low‐velocity anomaly at ∼200  m depth, likely an air‐filled cavity caused by partial collapse of the rock column into the temporary postdetonation cavity. A high‐velocity anomaly between 20 and 60 m depth represents spall‐related compaction of the shallow alluvium. Hints of low velocities are also present near the burial depth (⁠∼364  m⁠). The reflection seismic data show a prominent subhorizontal reflector at ∼300  m depth, a short‐curved reflector at ∼200  m⁠, and a high‐amplitude reflector at ∼50  m depth. Comparisons of the reflection sections to synthetic data and borehole stratigraphy suggest that these features correspond to the alluvium-tuff contact, the partial collapse cavity, and the spalled layer, respectively. [ABSTRACT FROM AUTHOR]

Two new analogues of CDDO-Imidazolide (CDDO-Im), namely 1-[2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4(-pyridin-2-yl)-1H-imidazole (“CDDO-2P-Im”) and 1-[2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4(-pyridin-3-yl)-1H-imidazole (“CDDO-3P-Im”) have been synthesized and tested for their potential use as chemopreventive drugs. At nanomolar concentrations, they were equipotent to CDDO-Im for inducing differentiation and apoptosis in U937 leukemia cells. As inflammation and oxidative stress contribute to carcinogenesis, we also assessed their cytoprotective potential. The new compounds suppressed inducible nitric oxide synthase (iNOS) expression in RAW264.7 macrophage-like cells and significantly elevated heme oxygenase-1 (HO-1) and quinone reductase (NQO1) mRNA and protein levels in various mouse tissues in vivo . Most importantly, pharmacokinetic studies performed in vitro in human plasma and in vivo showed that each new analogue was more stable than CDDO-Im. Much higher concentrations of the new derivatives were found in mouse liver, lung, pancreas and kidney after gavage in contrast to CDDO-Im. Because of their better bioavailability and their excellent anti-inflammatory profile in vitro , CDDO-2P-Im and CDDO-3P-Im were tested for prevention in a highly relevant mouse lung cancer model, in which A/J mice develop lung carcinomas after injection of vinyl carbamate, a potent carcinogen. CDDO-2P-Im and CDDO-3P-Im were as effective as CDDO-Im for reducing the size and the severity of the lung tumors. [ABSTRACT FROM AUTHOR]

Thesynthesis of dicyano abietane 11, a potential precursorto the biologically active tricyclic bis-cyano enone 6(TBE-31), was accomplished in eight steps from epoxide 13. The synthesis features a Lewis acid promoted stereoselective cyclizationof epoxide 13to generate the tricyclic ring system 12in one step. [ABSTRACT FROM AUTHOR]