1. Nasal oral fistula revealing Langerhans´ cell histiocytosis in adult patient: case report.
- Author
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Mzabi A, Thabet M, Tlili T, Zorgati H, Anoun J, Hassine IB, Karmeni M, Fredj FB, Mokni M, and Laouani C
- Subjects
- Adrenal Cortex Hormones administration & dosage, Adult, Histiocytosis, Langerhans-Cell complications, Histiocytosis, Langerhans-Cell drug therapy, Humans, Male, Nasal Cavity surgery, Oral Fistula etiology, Oral Fistula surgery, Vinblastine administration & dosage, Histiocytosis, Langerhans-Cell diagnosis, Nasal Cavity abnormalities, Oral Fistula diagnosis
- Abstract
Langerhans cell histiocytosis (LCH) is a rare systemic disease caused by proliferation of mature histiocytes; its association to histiocyto fibroma is rarely reported. It rarely affects adults. We report a case of systemic LCH, in an adult patient with osteolytic lesion causing a fistula between the left nasal cavity and hard palate, involving the bone, lung, lymph node and associated to multiple histiocyto fibroma. The patient was operating for a fistula, and he was treated by chemotherapy and corticosteroids. Langerhans´ cell histiocytosis is a rare case, especially in adult patient. The diagnosis was based on histological and immunohistochemical analyses. This patient was treated by steroids and chemotherapy., Competing Interests: The authors declare no competing interests., (Copyright: Anis Mzabi et al.)
- Published
- 2021
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