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Copyright of Die Urologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Les glucocorticoïdes sont largement utilisés pour le traitement de diverses maladies et affections dans un certain nombre de spécialités. Les effets néfastes des glucocorticoïdes oraux sur la santé osseuse sont bien documentés et l'ostéoporose cortico-induite est la cause la plus répandue d'ostéoporose provoquée par des médicaments et de fractures. On ne sait toutefois pas avec certitude si, ni dans quelle mesure, les glucocorticoïdes administrés par d'autres voies ont des effets sur le squelette. Cette revue présente les résultats disponibles à propos des effets des glucocorticoïdes administrés par voie inhalée, épidurale, intra-articulaire et topique sur les paramètres osseux. Bien que les données probantes soient limitées et peu robustes, il semble qu'une petite proportion des glucocorticoïdes administrés puisse être absorbés, pénétrer dans la circulation systémique et avoir des effets néfastes sur le squelette. Les glucocorticoïdes puissants, les fortes doses et une longue durée de traitement pourraient entraîner un risque accru de perte osseuse et de fractures. On trouve peu de données, et celles qui sont disponibles concernent uniquement les glucocorticoïdes inhalés, sur l'efficacité des anti-ostéoporotiques chez les patients recevant une corticothérapie administrée par d'autres modes que la voie orale. Des études complémentaires sont nécessaires pour clarifier la relation entre les différentes voies d'administration des glucocorticoïdes et les paramètres osseux et contribuer à formuler des recommandations de prise en charge optimale de ces patients. Glucocorticoids (GCs) are widely used by several specialties for the treatment of a variety of diseases and conditions. The unfavorable effect of oral GCs on bone health is well-documented. The ensuing from their use glucocorticoid-induced osteoporosis (GIOP) is the most common cause of medication-induced osteoporosis and fractures. It is uncertain, however, if, and in what extent, GCs administered by other routes affect the skeleton. In the present review, we quote current evidence on the effect of inhaled GCs, epidural and intra-articular steroid injections, and topical GCs on bone outcomes. Although evidence is limited and weak, it seems that a small proportion of the administered GCs may be absorbed, enter the systemic circulation, and adversely affect the skeleton. Potent GCs, higher doses, and longer treatment duration seem to infer the greater risk for bone loss and fractures. There are scarce data, and only for inhaled GCs, regarding the efficacy of antiosteoporotic medications in patients receiving GCs through routes other than oral. Further studies are needed to clarify the relationship between GC administration through these routes and bone outcomes and to help establishing guidelines for the optimal management of such patients. [ABSTRACT FROM AUTHOR]

Le coût des fractures ostéoporotiques est estimé en France à près de 7 milliards d'euros pour l'année 2019 soit 2,6 % des dépenses de santé. Le coût moyen d'une fracture de hanche en France est d'environ 22 000 euros la première année. Les coûts directs sont les plus importants, représentés par les frais d'hospitalisation et de soins de suite. Le coût de l'évaluation et de la prise en charge de l'ostéoporose représente moins de 1 % du coût moyen annuel. À l'avenir, l'impact financier et sociétal des fractures ostéoporotiques va augmenter en lien avec le nombre accru de fractures de fragilité liées au vieillissement de la population contrastant avec un manque d'évaluation et de prise en charge pharmacologique de l'ostéoporose. The cost of osteoporotic fractures in France is estimated at nearly 7 billion euros for 2019, or 2.6% of healthcare expenditure. The average cost of a hip fracture in France is around 22,000 euros in the first year. Direct costs are the most important, represented by hospitalization and nursing home. The cost of assessing and managing osteoporosis represents less than 1% of the average annual cost. In the future, the financial and societal impact of osteoporotic fractures is set to increase, due to the growing number of fragility fractures associated with an ageing population, coupled with a lack of assessment and pharmacological management of osteoporosis. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift für Rheumatologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Osteoporosis is the most common bone disease, affecting one in three women and one in five men over the age of 50 worldwide, ultimately affecting nearly 70% of women over the age of 80. The clinical consequence of osteoporosis, which also constitutes its major complication, is a fragility fracture. Globally, it is estimated that osteoporosis is responsible for 9 million fractures each year, or one fracture every 3 seconds. Therefore, its screening in general medicine appears essential. This observation leads to several questions: what is the prescribing attitude of general practitioners? What importance do they give to this screening in their practice? What are the possible obstacles to this screening? [ABSTRACT FROM AUTHOR]

Resumo Introdução: Alterações fisiológicas do envelhecimento contribuem para osteoporose e fraturas relacionadas à baixa concentração sérica de 25(OH)D. Objetivo: Investigar a associação entre concentração sérica de 25(OH)D, ingestão de alimentos fonte de vitamina D e cálcio, condições de saúde e presença de osteoporose e fraturas em idosos. Método: Estudo transversal com 274 idosos do Piauí. Realizado em duas etapas: questionário sobre ingestão de alimentos fonte de vitamina D, cálcio e condições de saúde (incluindo a variável desfecho, presença de osteoporose e fraturas) e coleta de sangue para exame bioquímico de concentração sérica de 25(OH)D. Realizou-se análise descritiva, inferencial e regressão logística. Resultados: A maioria dos idosos apresentava comorbidades (86,4%). A prevalência dos desfechos foi de 23,7% e 14,6%, respectivamente. Na análise múltipla, ingerir bebidas alcoólicas (OR=6,58; IC95% 1,88–23) e reposição com cálcio (OR=2,87; IC95% 1,25–6,61) mostraram-se associados às fraturas, enquanto sexo feminino (OR=5,69; IC95% 1,12–28,9) e reposição com cálcio (OR=5,62; IC95% 1,62–19,5) mostraram-se associados à osteoporose. As maiores medianas de 25(OH)D foram encontradas naqueles que consumiam queijo e iogurte regularmente (p=0,021). Conclusão: A análise das concentrações séricas de 25(OH)D apontou insuficiência, indicando a necessidade de intervenções para a mudança do estilo de vida.

Fragility fractures in older people are common and are often associated with nursing home admission in frail people. Only few institutionalized residents with documented osteoporosis receive pharmacologic osteoporosis treatment. Studies demonstrating the benefit of osteoporosis drug therapy in this multimorbid and vulnerable population are lacking. [ABSTRACT FROM AUTHOR]

Copyright of Die Unfallchirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The treatment of prostate cancer with androgen deprivation therapy (ADT) causes a decrease in bone density as a side effect. For prescribers of this treatment, knowledge of the prevention of osteoporosis and fracture risk is important, as well as knowledge about the indication for follow-up testing or indication for additional lifestyle measures and therapy. In this article we discuss the relationship of ADT with osteoporosis and fracture risk based on the literature and give recommendations based on the Dutch prostate cancer guideline and the recently published Dutch guideline on osteoporosis and fracture prevention. [ABSTRACT FROM AUTHOR]

[Display omitted] La survenue de fractures osseuses est fréquente dans la population âgée et chez les patients atteints d'un cancer, en particulier ceux qui présentent des métastases osseuses. L'incidence croissante du cancer liée au vieillissement de la population constitue un enjeu sanitaire majeur, y compris pour la santé osseuse. La prise en charge des patients âgés atteints d'un cancer doit prendre en compte l'hétérogénéité et les spécificités de cette population. Les outils de dépistage disponibles tels que le G8 et le VES13 tout comme l'évaluation gériatrique approfondie (EGA) ne couvrent pas les informations liées à la santé osseuse. Une évaluation des complications osseuses sera indiquée en fonction des syndromes gériatriques identifiés comme les chutes, les antécédents du patient et le plan de traitement oncologique. Certaines thérapies anticancéreuses ont un impact délétère sur le remodelage osseux et exposent au risque d'ostéoporose. L'hypogonadisme, induit par l'hormonothérapie et certaines chimiothérapies, est le principal facteur à l'origine d'une diminution de la densité minérale osseuse. Les thérapies oncologiques présentent également un risque de toxicité directe (chimiothérapie, radiothérapie ou corticostéroïdes) ou indirecte via les troubles électrolytiques (certaines chimiothérapies ou inhibiteurs de tyrosine-kinase) sur le remodelage osseux. La prévention des complications osseuses relève d'une prise en charge pluridisciplinaire. Certaines interventions proposées dans le cadre de l'EGA visent à améliorer la santé osseuse et réduire le risque de chute. Cette démarche est également fondée sur le traitement de l'ostéoporose et la prévention des complications associées aux métastases osseuses. La prise en charge des fractures, qu'elles soient liées ou non aux métastases osseuses, fait référence au concept d'orthogériatrie. Le rapport bénéfices-risques de l'opération, l'accès aux techniques mini-invasives, la pré-habilitation ou réhabilitation ainsi que le pronostic lié au cancer et aux syndromes gériatriques sont également pris en compte. La santé osseuse est une dimension essentielle en oncogériatrie. L'évaluation du risque osseux devrait faire partie intégrante de l'EGA en routine clinique et des outils spécifiques d'aide à la décision thérapeutique devront être développés. La prise en charge des complications osseuses doit être assimilée au parcours de soins du patient et l'approche oncogériatrique pluridisciplinaire se doit de prévoir une expertise rhumatologique. The occurrence of bone fractures is frequent in the elderly population, and in cancer patients, especially with bone metastases. The growing incidence of cancer associated with an aging population implies important health challenges, including bone health. Decisions on cancer care in older adults have to take into account older adults' specificities. Screening tools as G8 or VES 13 and evaluating tools as comprehensive geriatric assessment (CGA) do not include bone-related items. Bone risk assessment is indicated according to identification of geriatric syndromes such as falls, history, and the oncology treatment plan. Some cancer treatments disrupt bone turnover and decrease bone mineral density. This is mainly caused by hypogonadism, induced by hormonal treatments and some chemotherapies. Treatments can also cause direct (i.e. chemotherapy, radiotherapy or glucocorticoids) or indirect toxicity through electrolyte disorders (i. e. some chemotherapies or tyrosine kinase inhibitors) on bone turnover. Bone risk prevention is multidisciplinary. Certain interventions proposed in the CGA aim to improve bone health and reduce the risk of falling. It is also based on the drug management of osteoporosis, and the prevention of complications from bone metastases. Management of fractures, related or not to bone metastases, relates to the concept of orthogeriatrics. It is also based on the benefit-risk ratio of the operation, access to minimally invasive techniques, prehabilitation or rehabilitation, but also the prognosis related to cancer and geriatric syndromes. Bone health is essential in older cancer patient's care. Bone risk assessment should be part of CGA in routine use and specific decision-making tools should be developed. Bone event management must be integrated throughout the patient's care pathway and onco-geriatrics multidisciplinarity should include rheumatological expertise. [ABSTRACT FROM AUTHOR]

Osteoporosis is the most common weakening disease of the skeleton. It affects more than 200 million people worldwide. Since the international consensus conference of Hong Kong in 1993, that of Amsterdam in 1996, and the NIH in 2001, osteoporosis has been defined by a progressive decrease in bone mass and qualitative alterations of bone tissue, therefore of bone strength, predisposing the patient to an increased risk of fractures [1]. In 1994, the WHO defined diagnostic criteria for densitometric osteoporosis based on the measurement of bone mineral density (BMD) by DXA. Postmenopausal osteoporosis occurs in a specific hormonal context. It is a real silent epidemic, until fracture complications appear [2 , 3]. The development and greater availability of non-invasive methods for measuring bone mineral content have contributed to facilitating the screening and assessment of fracture risk. [ABSTRACT FROM AUTHOR]

Copyright of Rheuma Plus is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Osteoporotic pelvic ring fractures show a continuously increasing incidence. In addition to the fracture morphology, the clinical situation of the patients is also crucial for therapy. The osteoporotic fracture working group of the spine section of the German Society for Orthopaedics and Trauma Surgery (DGOU) has developed a score for the treatment decision that is based on the OF-Pelvis classification and on essential clinical parameters. The score includes the clinical parameters of mobilization ability, pain situation, fracture-related neurological deficits and risk factors for an increased surgical complication rate. In addition, the fracture morphology is determined according to the OF-Pelvis classification including the fracture modifiers. For each parameter, points are awarded or deducted depending on the characteristics and the total is then calculated. If a parameter cannot be determined, no point are awarded. A score below 8 means a recommendation for conservative therapy, while a score above 8 means a recommendation for surgical therapy. If there are exactly 8 points, conservative or surgical treatment is possible. The OF-Pelvis score was evaluated retrospectively in 5 trauma centers based on records and imaging in 107 patients and compared with the therapy actually carried out. There was an overall agreement of 91 % between the therapy recommendation of the OF-Pelvis score and the therapy actually carried out (conservative versus surgical). Collecting the score took about 5 minutes. The OF-Pelvis score is an easy-to-use decision-making aid for determining the indication for conservative or surgical treatment of osteoporotic pelvic ring fractures. [ABSTRACT FROM AUTHOR]

As the population ages, the incidence of fractures of the sacrum and pelvic ring is increasing. This represents a challenge for outpatient and inpatient care facilities. The Osteoporotic Fractures Working Group of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU) has developed the OF-Pelvis classification for these injuries with a view to making it reliable and easy to use. The OF-Pelvis classification divides these injuries into 5 categories. From OFP 1 to OFP 5, the injury severity and instability grade increases. Category OFP 1 corresponds to evidence of edema in the sacrum or pelvic ring without evidence of fracture on computed tomography. Category OFP 2 corresponds to a unilateral or bilateral fracture of the anterior pelvic ring on CT-scan. An OFP 3 fracture corresponds to a unilateral posterior sacral fracture with facultative fracture of the anterior pelvic ring. An OFP 4 fracture presents with a bilateral posterior sacral fracture. The highest severity is an injury which is transiliosacral or iliac and corresponds to the OFP 5 category. Three modifiers can be assigned. These indicate a higher degree of instability or further injuries. An avulsion of the transverse process of LWK 5 corresponds to modifier 1. Modifier 2 is assigned if there is dislocation of the fracture. Evidence of an edema in a location of the pelvic ring where no fracture is detectable on CT-scan corresponds to modifier 3. Initial testing of the assessment of categories and modifiers by multiple investigators showed substantial to near perfect agreement (Fleiss' kappa = 0.764-0.790 for the categories, Fleiss' kappa = 0.646-0.629 for the modifiers). The OF-Pelvis seems to be a reliable tool for the classification of osteoporotic sacral and pelvic ring fractures which can also be an aid in clinical practice for physicians not specialized in the treatment of such fractures due to its reliability and simplicity. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift für Gerontologie und Geriatrie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Osteoanabolic osteoporosis drugs have become better available. The osteoanabolic therapeutic principle has a stronger, faster-onset fracture-reducing effect than the antiresorptive preparations. It has also been newly recognized that the significance of a first fragility fracture as a risk factor is time-dependent: the less time that has elapsed since the first fracture, the higher the resulting re-fracture risk. Patients older than 65 years whose index fragility fracture occurred less than two years before are therefore grouped in a separate "Imminent Fracture Risk" category. These innovations were implemented by updating the osteoporosis therapy guideline. According to this guideline, patients in the "Imminent Fracture Risk" category should be offered osteoporosis therapy as soon as possible, in order to avoid as many fractures as possible. We are critical of an overly strict implementation of this algorithm in very old fracture patients. Our own data indicate that more than 30 % of this subpopulation do not experience the effect of a newly started osteoporosis therapy. We advocate a clinically based indication for osteoporosis therapy. For this, we propose a "Question Surprise" modified for osteological purposes. "Would I be surprised if I had to treat the same patient for a fracture again in a year?" If the question is answered with "No," then that patient could be a candidate for specific osteoporosis treatment. [ABSTRACT FROM AUTHOR]

Copyright of Implantologie is the property of Quintessenz Verlags GmbH and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Die Unfallchirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Die Radiologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Veel ouderen, vooral vrouwen, en hun artsen zien osteoporose nog steeds als een natuurlijk onderdeel van het ouder worden, in plaats van een te voorkomen of behandelbare medische aandoening. Hoogteverlies, hyperkyfose, rugpijn en fracturen worden geaccepteerd als een gevolg van het ouder worden. Een andere barrière voor het instellen van een behandeling is het idee dat het te laat is om daarmee te beginnen in een laat stadium van de ziekte. Hoewel de meeste onderzoeken naar fractuurreductie met medicatie niet waren ontworpen voor de ‘geriatrische’ populatie, was de gemiddelde leeftijd van de deelnemers aan de meeste klinische trials wel rond de 70 jaar. In alle grote onderzoeken kregen patiënten ook steeds calcium- en vitamine-D-suppletie. Uit de beschreven vergelijking van farmacologische opties blijkt dat de arts tegenwoordig de keuze heeft uit meerdere, bewezen effectieve middelen ter preventie van osteoporotische fracturen bij postmenopauzale vrouwen met een verhoogd fractuurrisico. Er zijn nu antifractuurgegevens bekend van calcium/vitamine D, raloxifene, bisfosfonaten, strontiumranelaat en parathormoon. Bisfosfonaten en strontiumranelaat zijn beide goede keuzes voor eerstelijns- of tweedelijnsbehandeling, terwijl parathormoon vooralsnog alleen als tweedelijnsbehandeling van osteoporose bij ouderen kan worden ingezet.

Este estudo objetivou estimar a prevalência de osteoporose em idosos atendidos em um centro de referência e identificar fatores associados. Trata-se de um estudo transversal, analítico, com coleta de dados em prontuários médicos e entrevistas aos idosos atendidos no Centro de Referência em Assistência à Saúde dos Idosos (CRASI), e que realizaram exame de densitometria óssea nos anos de 2017 e 2018. Utilizou-se análise bivariada para investigar a associação entre osteoporose e características do grupo: perfil sociodemográfico, Índice de Massa Corporal (IMC), hábitos de vida, cuidados e condições de saúde. As variáveis com associação até o nível de 20% (p ≤ .20) foram avaliadas de forma conjunta por regressão múltipla de Poisson com estimador robusto, admitindo-se para o modelo final apenas as variáveis com nível de significância de até 5%. A prevalência de osteoporose foi de 48.5%. No modelo final ficaram associadas as variáveis: sexo feminino (RP = 1.88; IC95%: 1.36 - 2.60), idade acima de 80 anos (RP = 1.55; IC95%: 1.29 - 1.85), IMC menor que 22 (RP = 1.23; IC95%: 1.02 - 1.49) e como protetor IMC acima de 27 (RP = .52; IC95%: .41 - .67). Concluindo,verificou-se alta prevalência de osteoporose e associação como fator modificável o baixo peso e outros não modificáveis: sexo e idade. Não foram identificadas associações com variáveis relacionadas aos hábitos de vida.

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Copyright of Die Unfallchirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Every day dental implants are being sought by young adults and elderly people. With the increase in this demand, more people with osseointegration problems due to diseases such as osteoporosis have emerged, due to which there has been a greater need in the search for resolutions for these deficits. Materials and Methods: For this literature review, articles found in PubMed, Scielo and google academic databases were used, with 842 articles found, 83 selected and 29 used. Conclusion: It is concluded that the greatest difficulty in implant dentistry in patients with osteoporosis is osseointegration and to improve the vitamin and hormonal deficits that cause it, drugs and vitamin supplements are necessary. [ABSTRACT FROM AUTHOR]

The purpose of this study was to compare bone health parameters (bone mineral content [BMC], bone mineral density [BMD], geometric indices of femoral neck [FN] strength (cross-sectional area [CSA], cross-sectional moment of inertia [CSMI], section modulus [Z], buckling ratio [BR] and strength index [SI]) and composite indices of FN strength (compression strength index [CSI], bending strength index [BSI], and impact strength index [ISI])) in middle-aged inactive men (n = 25) and middle-aged former basketball players (n = 18). The participants of the study were 43 middle-aged men; their ages ranged from 38 to 52 years. Dual-energy X-ray absorptiometry was used to evaluate body composition, BMD and geometric indices of FN strength. Composite indices of FN strength (CSI, BSI, and ISI) were calculated. Physical performance tests were used to evaluate the vertical jump (VJ), horizontal jump (HJ), triple jump (TJ), maximum power (MP) of the lower limbs (watts), maximal squat strength, maximal bench press strength, maximal leg extension strength, maximal barbell curl strength, maximal triceps extension strength, sprint performance (10 meters), and maximum oxygen consumption (VO 2 max, L/min). WB BMC, WB BMD, L1-L4 BMD, CSA, CSMI and Z were significantly higher in former basketball players compared to inactive men. MP, TJ, VJ, maximal squat strength and maximal bench press strength were significantly higher in former basketball players compared to inactive men. The present study suggests that former basketball practice is associated with greater bone health parameters in middle-aged men. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift für Gerontologie und Geriatrie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Dit onderzoek laat zien dat de verpleeghuisarts een belangrijke taak heeft in de preventie, diagnostiek en behandeling van osteoporose bij ouderen die ter revalidatie worden opgenomen in het verpleeghuis. Bij 96 patiënten met een status na heupoperatie (door fractuur of coxartrose) werd onderzoek verricht naar vitamine-D deficiëntie en calcium-inname. Hiervan had 36% een vitamine-D deficiëntie (vitamine-D < 30nmol/l) en 68% een te lage calcium-inname via de voeding (dagelijkse intake

Ocular inflammatory reactions secondary to treatment with bisphosphonates are a rare entity. Their physiopathological mechanism is still poorly understood but seems to be linked to an immunological reaction mediated by some cytokines. Observation: We report the case of a 63-year-old patient followed for severe osteoporosis and treated with zoledronate. The patient presented 6 weeks after the initiation of treatment with a decrease in visual acuity diagnosed as acute anterior uveitis. Conclusion: Acute anterior uveitis is an important entity to be aware of because a good evaluation and rapid management can reduce complications involving the visual prognosis. [ABSTRACT FROM AUTHOR]

Cet article présente les recommandations initiales de la Société française de rhumatologie (SFR) et du Groupe de recherche et d'information sur les ostéoporoses (GRIO) concernant le rôle de l'alimentation dans la prévention et le traitement de l'ostéoporose. Ces recommandations ont été élaborées par un groupe de travail constitué de rhumatologues, de médecins nutritionnistes et d'un gériatre. Quinze (15) questions issues de la pratique quotidienne ont été présélectionnées. Pour la revue de la littérature, le groupe de travail s'est concentré sur les effets de l'alimentation sur la densité minérale osseuse (DMO) et les fractures, examinant en priorité des méta-analyses d'études longitudinales et d'études interventionnelles sur l'alimentation. Il est recommandé d'adopter un régime de type méditerranéen et de consommer deux ou trois produits laitiers par jour. Cette combinaison garantit les apports en calcium et en protéines de haute qualité nécessaires au maintien de l'équilibre calcium-phosphore normal et au métabolisme osseux ; elle est, de plus, associée à une diminution du risque de fracture. À l'inverse, les régimes occidentaux déséquilibrés, les régimes végans, les régimes amaigrissants en l'absence de surpoids, la consommation d'alcool et la consommation quotidienne de sodas sont déconseillés. Les données scientifiques disponibles sur les effets bénéfiques pour la densité minérale osseuse et le risque de fracture sont soit insuffisantes, soit trop divergentes pour permettre de préconiser l'augmentation ou la restriction du thé ou du café, de vitamines autres que la vitamine D, d'aliments enrichis en vitamine D ou contenant des phytoœstrogènes, de boissons végétales enrichies en calcium, de compléments nutritionnels oraux ou de sources alimentaires de prébiotiques et de probiotiques. Il s'agit du premier ensemble de recommandations centré sur le rôle de l'alimentation dans la prévention et le traitement de l'ostéoporose. Des recherches supplémentaires sont nécessaires pour orienter et étayer les préconisations. This article presents the initial recommendations of the French Rheumatology Society (Société française de rhumatologie – SFR) and the Osteoporosis Research and Information Group (Groupe de recherche et d'informations sur les ostéoporoses – GRIO) on the role of diet in the prevention and treatment of osteoporosis. The recommendations were produced by a working group composed of rheumatologists, physician nutrition specialists and a geriatrician. Fifteen (15) questions pertaining to "daily practices" were preselected by the working group. For the literature review, the working group focussed mainly on the effects of diet on bone mineral density (BMD) and fractures, and primarily on meta-analyses of longitudinal studies and dietary intervention studies. A Mediterranean-type diet and the daily consumption of 2 to 3 dairy products are recommended. Together, these provide the calcium and "high quality" protein required to maintain a normal calcium-phosphorus balance and bone metabolism, and are associated with lower fracture risk. Conversely, unbalanced Western diets, vegan diets, weight-loss diets in non-overweight individuals, alcohol consumption and daily consumption of sodas are advised against. In terms of the beneficial effects on bone mineral density and fracture risk, current scientific data are either insufficient or too divergent to recommend increasing or restricting the consumption of tea or coffee, vitamins other than vitamin D, vitamin D-enriched or phytoestrogen-rich foods, calcium-enriched plant-based beverages, oral nutritional supplements, or dietary sources of prebiotics and probiotics. These are the first set of recommendations addressing the role of diet in the prevention and treatment of osteoporosis. More research is necessary to direct and support guidelines. [ABSTRACT FROM AUTHOR]

Exercise training plays an important role in maintaining the bone health and prevention of osteoporosis or age-related bone loss. Aerobic exercise, resistance exercise or a combination of both are used to maintain bone health. Mechanical loading induced by resistance exercise stimulates a number of mechanisms that help to maintain or improve bone mineral density. The present review article aims at summarizing the mechanisms and the use of resistance exercises for improving or maintaining the bone and muscle mass. Literature search was done using PubMed Central, CINAHL, sciencedirect.com with keywords resisted exercises, osteoporosis, postmenopausal and effect of resisted exercises in osteoporosis. Resistance exercises have a significant effect in maintaining the musculoskeletal health. Mechanical loading of the bone especially with high intensity exercises, leads to an improvement in the bone mineral density. Resistance exercises may help to regulate the bone health and prevent the development of osteoporosis. These can be included in the exercise programmes designed for osteoporotic or postmenopausal patients. [ABSTRACT FROM AUTHOR]

Primary hyperparathyroidism (PHPT) is usually diagnosed by the occurrence of hypercalcaemia. However, there are normocalcaemic forms, is this an early stage of primary hyperparathyroidism? The aim of our study is to describe the evolution of normocalcaemic hyperparathyroidism (nPH) and to evaluate the cardiovascular, bone and nephrological risk before and after surgery. Materials and methods: retrospective, descriptive and analytical study from September 2014 to September 2020, including patients followed up at the Endocrinology Diabetology and Nutrition Department of the Hassan II University Hospital of Fez for normocalcemic hyperparathyroidism. Results: 17 patients were identified who were followed up for HPTPn. The evolution was marked by the occurrence of complications indicating surgical treatment in 35% of cases. Post-operative follow-up showed a clear improvement in nephrolithiasis (p < 0.05), but no benefit on bone complications (p = 1.1). On the other hand, 65% of our patients did not benefit from surgical treatment, their follow-up showed the occurrence of osteoporosis in 11% of patients, nephrolithiasis in 23% and transient hypercalcaemia in 23% without progression to hypercalcaemic hyperparathyroidism. Conclusion: Our patients followed for nPPH did not progress to hypercalcaemic PPH, but rather presented with transient hypercalcaemia and other complications that may fall under the category of PPH complications. [ABSTRACT FROM AUTHOR]

Copyright of JBES: Brazilian Journal of Health Economics / Jornal Brasileiro de Economia da Saúde is the property of JBES: Brazilian Journal of Health Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abtract: Several in vivo studies show interesting correlations between microbiota and bone remodeling. The microbiota model and stimulate the immune system, which exerts a direct effect on the bone. The first clinical studies confirm these results and open new perspectives for the prevention of osteoporosis. [ABSTRACT FROM AUTHOR]

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