336 results on '"Ottens, Marcel"'
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2. Continuous downstream processing
3. Digital twin in high throughput chromatographic process development for monoclonal antibodies
4. Hydrodynamics of expanded bed adsorption studied through CFD-DEM
5. Model-based optimization of multistage ultrafiltration/diafiltration for recovery of canola protein
6. Model-based optimization approaches for pressure-driven membrane systems
7. Predicting protein retention in ion‐exchange chromatography using an open source QSPR workflow
8. Small, smaller, smallest: Miniaturization of chromatographic process development
9. Recent advances to accelerate purification process development: A review with a focus on vaccines
10. Using artificial neural networks to accelerate flowsheet optimization for downstream process development.
11. A Structured Approach to Recover Valuable Compounds from Agri-food Side Streams
12. A critical assessment of the Flory-Huggins (FH) theory to predict aqueous two-phase behaviour
13. Continuous adsorption in food industry: The recovery of sinapic acid from rapeseed meal extract
14. High throughput process development for the purification of rapeseed proteins napin and cruciferin by ion exchange chromatography
15. Model-based optimization of integrated purification sequences for biopharmaceuticals
16. A robotic platform to screen aqueous two-phase systems for overcoming inhibition in enzymatic reactions
17. Influence of ethanol and temperature on adsorption of flavor-active esters on hydrophobic resins
18. Column chromatography for separation and fractionation of flavor-active esters on hydrophobic resins and simulation of breakthrough behavior
19. Real‐time detection of mAb aggregates in an integrated downstream process
20. Using artificial neural networks to accelerate flowsheet optimization for downstream process development
21. Characterisation of the E. coli HMS174 and BLR host cell proteome to guide purification process development
22. Application of a fluorescent dye‐based microfluidic sensor for real‐time detection of mAb aggregates
23. Orientation of monoclonal antibodies in ion-exchange chromatography: A predictive quantitative structure–activity relationship modeling approach
24. An orientation sensitive approach in biomolecule interaction quantitative structure–activity relationship modeling and its application in ion-exchange chromatography
25. Selective adsorption of flavor-active components on hydrophobic resins
26. Recent Advances in Techniques for Flavor Recovery in Liquid Food Processing
27. BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
28. A note on the modelling of lubrication forces in unresolved simulations
29. Fourier transform assisted deconvolution of skewed peaks in complex multi-dimensional chromatograms
30. Robust high-throughput batch screening method in 384-well format with optical in-line resin quantification
31. Design of a microfluidic mixer channel: First steps into creating a fluorescent dye‐based biosensor for mAb aggregate detection
32. Thermodynamic description of peptide adsorption on mixed-mode resins
33. Resin selection for the separation of caffeine from green tea catechins
34. High-Throughput Process Development
35. Analytical characterization of complex, biotechnological feedstocks by pH gradient ion exchange chromatography for purification process development
36. Model-based rational methodology for protein purification process synthesis
37. Design of a microfluidic mixer channel: First steps into creating a fluorescent dye‐based biosensor for mAb aggregate detection.
38. Direct downstream catalysis: From succinate to its diethyl ester without intermediate acidification
39. Biofunctionalization and self-interaction chromatography in PDMS microchannels
40. High-throughput determination of adsorption equilibria for chromatographic oligosaccharide separations
41. Microfluidic diffusion measurements: The optimal H-cell
42. High-throughput protein precipitation and hydrophobic interaction chromatography: Salt effects and thermodynamic interrelation
43. Process analytical technique ( PAT ) miniaturization for monoclonal antibody aggregate detection in continuous downstream processing
44. Process development of a New Haemophilus influenzae type b conjugate vaccine and the use of mathematical modeling to identify process optimization possibilities
45. Prediction of protein retention times in hydrophobic interaction chromatography by robust statistical characterization of their atomic-level surface properties
46. Process analytical technique (PAT) miniaturization for monoclonal antibody aggregate detection in continuous downstream processing.
47. Automation and miniaturization: enabling tools for fast, high‐throughput process development in integrated continuous biomanufacturing.
48. Size-exclusion chromatographic protein refolding: Fundamentals, modeling and operation
49. Ion-exchange chromatographic protein refolding
50. High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents
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