30 results on '"Outeda, Patricia"'
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2. Creating new in vitro models to examine the role of Pkd1 in cell and tubular physiology
3. Aberrant Cellular Pathways in PKD
4. Polycystin-2 dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease
5. A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts
6. Methods to Study the Vasculature in ADPKD
7. #4181 THE AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE PROTEIN, FPC, RELEASES MITOCHONDRIA LOCALISING FRAGMENTS INVOLVED IN PREVENTING CYSTOGENESIS
8. Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype
9. Polycystin‐1 dependent regulation of polycystin‐2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum
10. TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease
11. A genetic screen in Drosophila reveals an unexpected role for the KIP1 ubiquitination-promoting complex in male fertility
12. GDNF drives rapid tubule morphogenesis in novel 3D in vitro model for ADPKD
13. Addition of an N-Terminal SNAP-Tag Induces a Novel Hypomorphic Pkd1 Allele
14. GDNF drives rapid tubule morphogenesis in a novel 3D in vitro model for ADPKD.
15. A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed
16. A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism
17. NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology
18. Cleavage of PC1 Is Not Required for Embryonic Vasculature Development
19. Transcriptomic Analysis of Pkd2-Deficient Kidneys Shows Altered Metabolic and Cytoskeleton Pathways Similar to Pkd1 Models and Evidence of an Increased Inflammatory Response
20. Generation of a New Mouse Model Harboring the Polycystin-2 Loss-of-Function D511V Patient Variant
21. Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease
22. The polycystin complex mediates Wnt/Ca2+ signalling
23. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism
24. Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development
25. Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat
26. Novel ARPKD mouse model with near complete deletion of Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus has multiple phenotypes but no renal cysts
27. Pkd1 and Pkd2 Are Required for Normal Placental Development
28. A Novel Pattern of Mutation in Uromodulin Disorders: Autosomal Dominant Medullary Cystic Kidney Disease Type 2, Familial Juvenile Hyperuricemic Nephropathy, and Autosomal Dominant Glomerulocystic Kidney Disease
29. Polycystin-1 dependent regulation of polycystin-2 via GRP94, a member of HSP90 family that resides in the endoplasmic reticulum.
30. Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution.
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