1,062 results on '"Ovaa, Huib"'
Search Results
2. EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers
3. Allosteric control of Ubp6 and the proteasome via a bidirectional switch
4. Ubiquitin-specific protease 8 controls B cell proteostasis and cell survival in multiple myeloma
5. USP8 promotes cancer progression and extracellular vesicle‐mediated CD8+ T cell exhaustion by deubiquitinating the TGF‐β receptor TβRII
6. K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap
7. Global non-covalent SUMO interaction networks reveal SUMO-dependent stabilization of the non-homologous end joining complex
8. Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry
9. How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling
10. Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response
11. Opportunities for Small Molecules in Cancer Immunotherapy
12. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler
13. Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly
14. Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition
15. Synthetic ubiquitinated proteins meet the proteasome : Distinct roles of ubiquitin in a chain
16. Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
17. IMI European Lead Factory — democratizing access to high-throughput screening
18. Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features
19. Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
20. SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock
21. USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism
22. Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies
23. Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?
24. Microwave-assisted diastereoselective two-step three-component synthesis for rapid access to drug-like libraries of substituted 3-amino-β-lactams
25. Differential Dependence of CD4+ CD25+ Regulatory and Natural Killer-Like T Cells on Signals Leading to NF-κB Activation
26. Activity-Based Ubiquitin-Specific Protease (USP) Profiling of Virus-Infected and Malignant Human Cells
27. Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation
28. Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2
29. Tools to investigate the ubiquitin proteasome system
30. Advancing our Understanding of Ubiquitination Using the Ub-Toolkit
31. An Interaction Landscape of Ubiquitin Signaling
32. Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
33. Identification and characterization of diverse OTU deubiquitinases in bacteria
34. Profiling DUBs and Ubl-specific proteases with activity-based probes
35. Cracking the Ubiquitin Code: the Ubiquitin Toolbox
36. Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide
37. Creating molecules that modulate immune responses
38. USP16 is an ISG15 cross-reactive deubiquitinase targeting a subset of metabolic pathway-related proteins
39. Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing
40. Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
41. The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases
42. Synthetic and semi-synthetic strategies to study ubiquitin signaling
43. Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease
44. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake
45. Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity
46. How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling
47. USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
48. USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.
49. Supplementary Figure S5 from Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis
50. Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2
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