Search

Purpose: To report anatomical and functional results in cases where we applied free internal limiting membrane (ILM) flap transplantation as primary or secondary surgery in large or persistent idiopathic macular holes (MHs). Materials and Methods: Ten eyes of 10 consecutive patients who underwent free ILM flap transplantation combined with pars plana vitrectomy surgery due to large or persistent MHs (diameter> 400 µm), and who used silicone-oil as an endotamponade were reviewed retrospectively. All patients underwent detailed ophthalmological examination and optical coherence tomography measurements at the first, third, sixth, and twelfth months postoperatively. Silicone-oil was removed in all cases at the third months postoperatively. The rates of anatomical closure, bestcorrected visual acuity (BCVA) values, and ellipsoid zone disruption (EZD) values were compared within the preoperative and postoperative periods. Results: The mean age of the patients was 69.20±4.94 years. Seven patients (70.0%) were female, and 3 patients (30.0%) were male. Anatomical closure was achieved in all eyes postoperatively. The mean BCVA values increased compared to baseline (0.95±0.27) at postoperative first month (0.93±0.34), and third months (0.87±0.32), but this increase was not statistically significant (p=0.809, p=0.237, respectively). The mean BCVA values significantly improved compared to baseline at postoperative sixth months (0.54±0.28), and twelfth months (0.47±0.21) (p=0.000, p=0.000, respectively). The mean EZD diameter significantly decreased compared to baseline at all follow-up visits. No complications were observed. Conclusions: Free ILM flap transplantation and the use of silicone-oil as an endotamponade provide an increase in BCVA levels, high anatomic closure rates, and improvement in EZD. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the posterior vitreous release rates after a single injection of expansile gas in patients with focal vitreomacular traction (VMT) syndrome. Materials and Methods: Thirteen eyes of 13 consecutive patients with focal symptomatic VMT were reviewed retrospectively. Intravitreal injection of 0.3 mL of pure perfluoropropane (C3F8) was performed. Patients were instructed to bob their head forwards and backwards similar to the head movements of a 'drinking bird' until VMT release. A full ophthalmic examination and optical coherence tomography (OCT) was performed at each visit. Results: The mean age of the patients was 66.23±10.01. Seven patients (53.8%) were female, and 6 patients (46.2%) were male. VMT was released in 12 patients (93.7%), and the mean release time was 7.58 days (1-14 days). In two eyes (15.4%) with VMT associated with the full thickness macular hole (FTMH), the macular hole was not closed despite the posterior hyaloid release. The mean pre-treatment best-corrected visual acuity (BCVA) improved significantly from 0.71±0.34 LogMAR to 0.54±0.28 LogMAR after the treatment (p=0.045). The mean central macular thickness (CMT) decreased significantly from 338.46±65.00 µm to 282.77±62.26 µm (p=0.013). In the preoperative period, the mean horizontal length of vitreomacular adhesion (HLVMA) was 691.92±268.24 µm. No correlation was found between HLVMA and release time (p=0.828). No complications were observed. Conclusions: Pneumatic vitreolysis is a relatively safe, minimally invasive and effective treatment option for symptomatic focal VMT syndrome. [ABSTRACT FROM AUTHOR]

AbstractPurposeMethodsResultsConclusionThis study aimed to assess and compare the retinal toxicity associated with silicone oil (SO) and perfluoropropane (C3F8) tamponade following vitreoretinal surgery for fresh rhegmatogenous retinal detachment (RRD), utilizing the office-based Diopsys® NOVA™ system for evaluation.Patients who underwent vitreoretinal surgery for fresh RRD and had SO (group 1) or C3F8 (group 2) tamponade were included in a prospective analysis. Flicker full field electroretinography (ffERG) and pattern electroretinography (PERG) tests were performed at 6 months postoperatively.Postoperative best corrected visual acuity (logMAR) was significantly different in group 1 and group 2 patients, 0.48 ± 0.3 and 0.30 ± 0.2, respectively. No significant disparities were found in demographic variables. Flicker ffERG and PERG recordings revealed notable alterations in retinal function parameters in the group 1 compared to the group 2.Our findings suggest a correlation between SO tamponade and retinal dysfunction, evidenced by office-based ERG measurements. The Diopsys® NOVA™ protocol offers clinical ease in assessing retinal function. Further controlled studies are essential to validate these findings and guide clinical practice effectively. [ABSTRACT FROM AUTHOR]

Objectives: To evaluate the reliability of optical biometry for correct intraocular lens (IOL) power calculation in eyes with macula-off rhegmatogenous retinal detachment (RRD) via comparing the axial lengths (AL) measured with optical biometry preoperatively and postoperatively. Methods: This retrospective study was conducted with 25 eyes of 25 patients who underwent combined surgery (phacoemulsification and pars plana vitrectomy (PPV)) with the diagnosis of RRD with macular involvement. Best-corrected visual acuity (BCVA), biomicroscopic examination, intraocular pressure measurement and full fundoscopic examination were performed in all patients. Axial length was measured using optical biometry in all patients. The AL measurements were repeated in the postoperative third month in the patients using gas tamponade during vitreoretinal surgery and in the third month after the silicone oil removal in patients using silicone-oil tamponade during vitreoretinal surgery. Results: The mean age of the patients was 61.60±7.33. Fifteen patients (60%) were female, and 10 (40%) were male. Postoperative BCVA values (0.40±0.28) were significantly higher than the preoperative BCVA values (0.14±0.22) (p<0.05). The preoperative mean value of AL was measured as 24.66±1.90 and the postoperative mean value of AL was 24.67±1.91. There was no statistically significant difference between the measured AL values in the preoperative and postoperative periods (p=0.258). Conclusion: Combined surgery (phacoemulsification and PPV) is a frequently applied method in RRD treatment. The correct AL measurement is important for the removal of refractive errors due to AL measurement in patients with macula-off RRD. Optical biometry provides accurate results in these cases. [ABSTRACT FROM AUTHOR]

Objectives: To compare the pain perception and treatment duration in patients undergoing panretinal photocoagulation (PRP) for high-risk proliferative diabetic retinopathy (PDR) using Navilas laser versus conventional laser., Methods: A study was conducted involving 40 patients with bilateral high-risk PDR. Each patient underwent PRP with conventional laser in one eye and Navilas laser in the other. Laser parameters, including spot size and pulse duration were standardized. Pain perception was evaluated using Verbal Rating Scale (VRS) and Visual Analogue Scale (VAS)., Results: The Navilas and conventional laser groups showed no significant differences in baseline visual acuity, lens status, intraocular pressure, cup-to-disc ratio, or cystoid macular edema. The duration of laser treatment was significantly shorter with Navilas laser group (517.3±48.78 seconds, p<0.001). Pain scores (VAS and VRS) were significantly lower in the Navilas laser group (p<0.001, p=0.002 respectively) than in conventional laser group. There was no correlation between VAS and VRS scores and laser time in both the Navilas and conventional laser groups (p>0.05)., Conclusion: Utilizing the Navilas laser for PRP in PDR patients offers advantages over conventional lasers, including reduced pain and expedited procedures. These findings contribute valuable insights for optimizing clinical decisions, potentially enhancing patient compliance and minimizing the risk of visual deterioration in diabetic retinopathy treatment., Competing Interests: The authors have no conflicts of interest to declare., (© Copyright 2024 by The Medical Bulletin of Sisli Etfal Hospital.)

Purpose: This study aimed to assess and compare the retinal toxicity associated with silicone oil (SO) and perfluoropropane (C3F8) tamponade following vitreoretinal surgery for fresh rhegmatogenous retinal detachment (RRD), utilizing the office-based Diopsys ® NOVA ™ system for evaluation., Methods: Patients who underwent vitreoretinal surgery for fresh RRD and had SO (group 1) or C3F8 (group 2) tamponade were included in a prospective analysis. Flicker full field electroretinography (ffERG) and pattern electroretinography (PERG) tests were performed at 6 months postoperatively., Results: Postoperative best corrected visual acuity (logMAR) was significantly different in group 1 and group 2 patients, 0.48 ± 0.3 and 0.30 ± 0.2, respectively. No significant disparities were found in demographic variables. Flicker ffERG and PERG recordings revealed notable alterations in retinal function parameters in the group 1 compared to the group 2., Conclusion: Our findings suggest a correlation between SO tamponade and retinal dysfunction, evidenced by office-based ERG measurements. The Diopsys ® NOVA ™ protocol offers clinical ease in assessing retinal function. Further controlled studies are essential to validate these findings and guide clinical practice effectively.

Purpose: It was aimed to compare corneal endothelial changes during the initial 12-month period in which patients started using atorvastatin after a diagnosis of acute coronary syndrome (ACS)., Methods: Forty-six participants (group 1) who underwent cardiac angioplasty and stenting for ACS and started using 80 mg atorvastatin in the early period were included in the study. In the study, a control group comprising 71 healthy adults (group 2) was included. These individuals did not use medication for any known systemic disease, had never taken statins, had no history of ocular surgery, and did not have any cornea-related eye diseases. Baseline and 12th month endothelial evaluations of group 1 and 2 participants were compared using specular microscopy., Results: There were 28 female and 18 male participants in group 1 and 48 female and 23 male participants in group 2 (P = 0.455). The mean baseline corneal endothelial cell density (CECD) was not significantly higher in group 1 compared to group 2 (2471.4 ± 200 cells/mm2 vs 2428.2 ± 539.8 cells/mm2, P = 0.230). When the change between baseline and 12th month CECD was examined, the decrease in group 2 was significantly different from that in group 1 (-15,2 ± 31,9 and -44,8 ± 49,6, P = 0,002). Although the percentage of hexagonal cells decreased significantly in group 2 participants, no significant change was observed in group 1 (respectively; P < 0.001, P = 0.073). The endothelial cell coefficient of variation did not differ significantly in group 1 participants over a 1-year period (P = 0.192), and a significant increase was observed in group 2 (P < 0.001)., Conclusion: This study revealed that atorvastatin may have a positive effect on corneal endothelium cell density and morphology., (Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.)