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Objective: To describe a compounding training plan in a tertiary hospital pharmacy service. The project aimed pharmacy assistant technicians to use a digital training platform and simulation techniques., Methods: Two training programs were designed, one for sterile and the other for non-sterile drugs. Each programme consists of several phases: a basic online training course (digital e-learning platform), a practical simulation workshop, a supervised practice in real conditions, and a final verification by the pharmacist to qualify the technician. Both programs include continuous and accredited evaluation by the hospital's Continued Education Commission. A satisfaction survey on training (e-lerning platform) was designed and conducted for pharmacy technicians (sterile and non-sterile)., Results: The project has been running for 3 years. Six specialist pharmacists from different areas involved in compounding are responsible for training and continuous evaluation. Twenty-one technicians have been trained, and nineteen have obtained qualifications. Two of them were found to be unfit. Currently, we employ13 pharmacy technicians who were initially trained. The participation rate in the satisfaction survey on training (e-learning platform) was 61.5% (n=8) out of a total number of current developers (n=13). Overall, 62.5% of technicians reported being satisfied or very satisfied, while the remaining 37.5% were indifferent., Conclusions: Compounding training program is currently in its third year. It has been crucial in delegating tasks to pharmacy technicians. The use of digital technology is essential in this training. We consider that, specific training in compounding, is indispensable and should be included in the academic plan for pharmacy technicians., Competing Interests: Declaration of Competing Interest None declared., (Copyright © 2023 Sociedad Española de Farmacia Hospitalaria (S.E.F.H). Publicado por Elsevier España, S.L.U. All rights reserved.)

Objective: To describe a compounding training plan in a tertiary hospital Pharmacy Service. The project aimed to train Pharmacy Assistant Technicians using a digital training platform and simulation techniques., Methods: Two training programmes were designed, one for sterile and the other for non-sterile drugs. Each programme consists of several phases: a basic online training course (digital e-learning platform), a practical simulation workshop, a supervised practice in real conditions and a final examination by the pharmacist to qualify the technician. Both programmes include a continuous and accredited evaluation by the hospital's Continuing Education Commission. A satisfaction survey on training (e-learning platform) was designed and conducted for pharmacy technicians (sterile and non-sterile)., Results: The project has been running for three years. Six specialist pharmacists from the different areas involved in compounding are responsible for training and continuous evaluation. Twenty-one technicians were trained, 19 were qualified, and two of them were unsuccessful. Nowadays, we have 13 pharmacy technicians out of those who were originally trained. Participation in the training satisfaction survey (e-learning platform) was 61.5% (n = 8) of the total number of current developers (n = 13). Overall satisfaction was good with 62.5% of technicians satisfied or very satisfied and the remainder were indifferent (37.5%)., Conclusions: The compounding training program is now in its third year. It has been crucial in delegating tasks to Pharmacy technicians. The use of digital technology is essential in training. We believe that specific training in compounding, is essential and should be included in the pharmacy technician curriculum., (Copyright © 2023. Publicado por Elsevier España, S.L.U.)

Background: The treatment of choice for patients with severe haemophilia is prophylaxis with clotting factor. Effective prophylaxis requires optimal adherence. Most published studies are based on surveys and interviews with patients or their parents. However, studies based on objective measurements of adherence are few and inconclusive., Objective: The main purpose of this study was to assess adherence to prophylaxis using an objective method in patients with haemophilia aged 12 to 25years as well as to assess its potential association with bleeding episodes. Secondary objectives included comparing objective and subjective adherence (questionnaire) and identifying factors potentially associated with treatment adherence., Methods: A retrospective observational study was designed to collect data on treatment adherence and clinical course of patients in 2013. The study included haemophilia patients on prophylaxis with clotting factor concentrate; the age range was 12 to 25years. Objective adherence to treatment was measured through pharmacy dispensing records. Dispensing dates within 2013 were used for calculation. Adherence (%) was calculated by dividing the total number of International Units (IU) of factor dispensed by the total estimated number of IU and multiplying by 100. Subjective adherence was measured using an ad hoc questionnaire which was completed by the patient. The number of bleeding episodes (joint, muscle and others) was obtained from interviews with the patient at the consultation with the pharmacist and was subsequently confirmed with the patient's clinical history. Other parameters were also evaluated., Results: We included 52 patients in the study. Average adherence of patients resulting from the analysing of dispensing records was 85.72 (SD=23.76%). The global average of bleeding episodes was 2.2 (SD=2.69). 32.6% (seventeen) patients presented with at least one joint bleeding episode versus 67.3% (thirty five) who showed no joint bleeding episodes. Likewise, only 10% (five) patients presented with one muscle bleeding episode. Even though a significant association between the rate of objective adherence and the number of bleeding episodes was not observed, a higher number of hemarthrosis was observed in less-adherent patients. Subjective adherence perceived by patients as reported by the questionnaire showed that 36 (83.7%) of the 43 patients who completed the questionnaire considered their adherence as good, whereas 7 (16.3%) of the 43 patients considered it as fair. A statistically significant relationship was found between objective adherence expressed as a percentage using dispensing records, and subjective adherence perceived by the patient (p=0.004). The other parameters evaluated were not associated with adherence to prophylaxis., Conclusions: Measuring objective adherence using pharmacy dispensing records is a simple and useful tool. No significant correlation was found between the rate of objective adherence observed and the number of bleeding episodes; however, a higher number of hemarthrosis was observed in less-adherent patients., (Copyright © 2016 Elsevier Ltd. All rights reserved.)