Search

The end of the villae and the changing face of the rural landscape in the ager of the civitates of Emporiae and Gerunda During much of the imperial period, the villa remained a fundamental element in the organisation of the territory, carrying out its essential functions as a place of residence and a centre for farming activity. Currently, the archaeological data on our territory enable us to establish a set of patterns that coincide with the proposals of other researchers presented in more global synthesis papers on the evolution and purpose of the villas. Instead of analysing the characteristics in detail, in this paper we would like to highlight that during the fifth century the predominant role of villas began to fade until it disappeared completely. In some cases, this final process was preceded by a functional transformation of many spaces. Former residential units were adapted to new production or craft activities and also converted into small funerary areas. This process of abandoning villas was associated with new forms of population that, gradually and following completely different patterns, completely changed the face of the rural landscape.

Copyright of Ausa is the property of Patronat d'Estudis Osonencs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ausa is the property of Patronat d'Estudis Osonencs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Display omitted]

Copyright of Ausa is the property of Patronat d'Estudis Osonencs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Ausa is the property of Patronat d'Estudis Osonencs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

La intoxicación por consumo de hongos es un fenómeno estacional que se produce con relativa frecuencia en áreas geográficas donde es habitual su consumo, en especial de especies silvestres. Dependiendo del tipo de hongo ingerido pueden aparecer distintos cuadros clínicos (gastrointestinal, nefrotóxico, alucinatorio, etc.). El cuadro más grave es el hepatotóxico, asociado a una alta mortalidad, y causado por hongos que contienen amatoxinas (síndrome ciclopeptídico). Presentamos una revisión actualizada de las características de las amatoxinas, su cinética y mecanismo de acción, los métodos utilizados para su determinación analítica, así como las diferentes opciones para el tratamiento de la intoxicación.

A través de Internet recientemente se han comercializado algunas sustancias estimulantes estructuralmente parecidas a neurotransmisores derivadas de medicamentos ya retirados, que potencialmente pueden causar cuadros clínicos de diversa gravedad. Su efecto estimulante y el hecho de que aparecen antes de prohibirse su consumo explican la denominación genérica de legal highs. La exposición a estas sustancias se manifiesta como cuadros parecidos a los del consumo de productos como fenciclidina, anfetaminas o cocaína, ya que muy probablemente compartan mecanismos de acción sobre la recaptación de dopamina en los núcleos cerebrales implicados en el comportamiento de gratificación. La escasez de información médica contrastada, y las dificultades para disponer de material de calibración constituyen un reto diagnóstico. El desoxipipradol, sintetizado hace más de 6 décadas para el tratamiento del trastorno hipercinético, fue relegado por el metilfenidato, un compuesto análogo. En 2009 reapareció como droga recreativa responsable de algunos cuadros clínicos de intoxicación.

Copyright of Ausa is the property of Patronat d'Estudis Osonencs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Los conocimientos relativos a los factores que influyen en las concentraciones de CA 125 ha conducido a cuestionarse la validez de un único valor límite. Los objetivos del trabajo fueron valorar los valores de CA 125 en función de la edad, presencia o ausencia de menopausia, índice de masa corporal (IMC), hábito tabáquico, paridad, variabilidad durante el ciclo menstrual, variabilidad biológica, índice de individualidad y diferencia crítica. Se incluyó a 65 mujeres sanas distribuidas en 2 grupos: sin y con menopausia. Los principales resultados demuestran que existe una clara relación entre las concentraciones de CA 125 y la edad, que en mujeres sin menopausia la concentración de CA 125 fue superior respecto a las mujeres con menopausia, con p95 de 30,52 y 18,30 U/ml, respectivamente. No encontramos variaciones durante el ciclo menstrual, aunque existe la probabilidad de encontrar valores superiores al valor límite convencional durante la fase folicular. La variabilidad biológica intra e interindividual en mujeres sin menopausia fue del 14,23 y el 43,57%, respectivamente, mientras que la variabilidad biológica interindividual en mujeres con menopausia fue del 36,25%. La diferencia crítica fue del 42,73% y el índice de individualidad de 0,11. No encontramos diferencias en función de la paridad ni del hábito tabáquico. Tampoco encontramos una relación respecto al IMC.

The Christian conquest of Murcian lands in the 13th century—at that time under the Moslem dominance—, started by Jaime the First of Aragón culminated by Alfonso the Tenth of Castile, meant the settlement in this territory of a quite important mass of settlers that spoke different romanic varieties. Departing from the analysis of the play Libros de Repartimiento of Murcia, Orihuela and Lorca, it can be fancied how the sociolinguistic situation of the Murcian area was during the Late Middle Age. It appears as unquestionable that the present Murcian dialect must be considered as a result of the contact between Catalan and Castilian during the 13th and 14th centuries. Colomina (1997) studied the Catalan influence in Murcian texts from the 13th to the 17th century. Catalanisms abound in the agriculture and fishing sector but also in urban activities as the building sector or the textile industry. In this work, the previous studies will be completed with the analysis of Murcian Catalanisms, departing from the dialectal vocabularies and the popular literature from the 19th and 20th centuries.

Recently, there has been an interest in the use of tacrolimus for the treatment of rheumatoid arthritis (RA). The role of rheumatoid factor (RF) as a cause of immunoassay interferences is well known. This study is the first to investigate the susceptibility of a tacrolimus immunoassay to interference by RF. Tacrolimus apparent concentrations were determined using the antibody conjugated magnetic immunoassay (ACMIA) run on the Dimension RxL Immunoassay System in 100 randomly selected samples previously submitted for routine diagnostic or monitoring of RA in patients not receiving tacrolimus. Fifty of them had an RF concentration exceeding 100 IU/L and 50 had an RF concentration below 20 IU/L. Samples with tacrolimus apparent whole-blood concentrations above 2.3 ng/mL (limit of quantification of the ACMIA assay alleged by the vendor) were considered as potential false positives. No positive tacrolimus result was found among the 50 samples with serum RF < 20 IU/mL. Among the 50 selected samples from patients with RF > 100 IU/mL (RF range 110-2650 IU/mL), 2 were positive for tacrolimus with ACMIA. In both cases, the pretreatment of these samples with an immunoglobulin blocking agent reduced the apparent tacrolimus concentrations to below the limit of detection. This was confirmed using the alternative and reference tacrolimus assays, both of which reported results below their respective limits of detection. The measured human anti-mouse antibodies levels were found to be elevated. These results show that certain patients with positive RF can have false-positive tacrolimus results using the tacrolimus ACMIA-Flex immunoassay on a Dimension RXL analyzer, which was not the case with 2 other techniques. The interference with the tacrolimus ACMIA results was suppressed after preincubation with an immunoglobulin blocking reagent.