10 results on '"P. Pelechano-Gómez"'
Search Results
2. Primary lymphoma of the prostate: A report of two cases
- Author
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V. López Prior, I. Martin García, P. Pelechano Gómez, and M. Barrios Benito
- Subjects
Radiological and Ultrasound Technology ,Biophysics ,Radiology, Nuclear Medicine and imaging - Published
- 2022
- Full Text
- View/download PDF
3. Effect of Focal vs Extended Irreversible Electroporation for the Ablation of Localized Low- or Intermediate-Risk Prostate Cancer on Early Oncological Control: A Randomized Clinical Trial
- Author
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Zhang, Kai, Teoh, Jeremy, Laguna, Pilar, Dominguez-Escrig, Jose, Barret, Eric, Ramon-Borja, Juan Casanova, Muir, Gordon, Bohr, Julia, Pelechano Gómez, Paula, Ng, Chi-Fai, Sanchez-Salas, Rafael, and de la Rosette, Jean
- Abstract
IMPORTANCE: Focal ablative irreversible electroporation (IRE) is a therapy that treats only the area of the tumor with the aim of achieving oncological control while reducing treatment-related functional detriment. OBJECTIVE: To evaluate the effect of focal vs extended IRE on early oncological control for patients with localized low- and intermediate-risk prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: In this randomized clinical trial conducted at 5 centers in Europe, men with localized low- to intermediate-risk prostate cancer were randomized to receive either focal or extended IRE ablation. Data were collected at baseline and at regular intervals after the procedure from June 2015 to January 2020, and data were analyzed from September 2021 to July 2022. MAIN OUTCOMES AND MEASURES: Oncological outcome as indicated by presence of clinically significant prostate cancer (International Society of Urological Pathology grade ≥2) on transperineal template-mapping prostate biopsy at 6 months after IRE. Descriptive measures of results from that biopsy included the number and location of positive cores. RESULTS: A total of 51 and 55 patients underwent focal and extended IRE, respectively. Median (IQR) age was 64 years (58-67) in the focal ablation group and 64 years (57-68) in the extended ablation group. Median (IQR) follow-up time was 30 months (24-48). Clinically significant prostate cancer was detected in 9 patients (18.8%) in the focal ablation group and 7 patients (13.2%) in the extended ablation group. There was no significant difference in presence of clinically significant prostate cancer between the 2 groups. In the focal ablation group, 17 patients (35.4%) had positive cores outside of the treated area, 3 patients (6.3%) had positive cores in the treated area, and 5 patients (10.4%) had positive cores both in and outside of the treated area. In the extended group, 10 patients (18.9%) had positive cores outside of the treated area, 9 patients (17.0%) had positive cores in the treated area, and 2 patients (3.8%) had positive cores both in and outside of the treated area. Clinically significant cancer was found in the treated area in 5 of 48 patients (10.4%) in the focal ablation group and 5 of 53 patients (9.4%) in the extended ablation group. CONCLUSIONS AND RELEVANCE: This study found that focal and extended IRE ablation achieved similar oncological outcomes in men with localized low- or intermediate-risk prostate cancer. Because some patients with intermediate-risk prostate cancer are still candidates for active surveillance, focal therapy may be a promising option for those patients with a high risk of cancer progression. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01835977
- Published
- 2023
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- View/download PDF
4. Primary lymphoma of the prostate: A report of two cases
- Author
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López Prior, V., Martin García, I., Pelechano Gómez, P., and Barrios Benito, M.
- Abstract
The primary lymphoma of prostate is rare, representing 0.2–0.8% of extranodal lymphomas and 0.1% of all prostate neoplasias.
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- 2022
- Full Text
- View/download PDF
5. Nephrometry scores: Interobserver reproducibility and perioperative factors prediction
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C. Rodríguez-Torreblanca, I.M. Ortiz-Rodríguez, Miguel Ramírez-Backhaus, C. Moreno-Alarcón, José Rubio-Briones, E. Solsona-Narbón, and P. Pelechano-Gómez
- Subjects
Reproducibility ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Interobserver reproducibility ,Retrospective cohort study ,General Medicine ,Perioperative ,urologic and male genital diseases ,Positive correlation ,Pearson product-moment correlation coefficient ,Nephrectomy ,Surgery ,Low complexity ,symbols.namesake ,symbols ,medicine ,Radiology ,business - Abstract
Objectives To validate the relation of the nephrometry scores in a series of patients who underwent partial nephrectomy with perioperative parameters and the urologist–radiologist reproducibility. Materials and methods A retrospective study of open and laparoscopic partial nephrectomy patients performed between 2005 and 2012 registered in prospective filled out database. An urologist and a radiologist calculated the RENAL, PADUA and C-index for 86 patients. We carried out a comparative study of the results using the Spearman and Pearson correlation indexes. Results Distribution according to the complexity of the tumors with the RENAL calculation was: 42 (49%) low, 35 (41%) moderated and 9 (11%) high complexity. According to PADUA: 35 (41%) low complexity, 32 (37%) intermediate and 19 (22%) high. No statistically significant correlation was found for the appearance of operative complications and the pathology results in case of RENAL and PADUA. A correlation was found in the case of PADUA in relation to the warm ischemia time. Positive correlation according to Spearman's index was found in RENAL, PADUA and C-index between urologist and radiologist evaluations. Conclusions Nephrometry scores can be a useful tool to plan the surgical technique or approach. However, it is not clear if they are really predictors of surgical or pathologic parameters. The correlation between the urologist and radiologist seems to be sufficient to recommend their use by both specialties.
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- 2014
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6. Suburethral male sling: Correlation between continence outcomes and magnetic resonance findings
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A. Collado Serra, José Rubio-Briones, J. Domínguez-Escrig, Isabel Martin, C. Mir, J. Cervera, Miguel Ramírez-Backhaus, Juan Casanova, P. Pelechano Gómez, Álvaro Gómez-Ferrer, and Inmaculada Iborra
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medicine.medical_specialty ,medicine.diagnostic_test ,Male sling ,business.industry ,Urology ,medicine ,Magnetic resonance imaging ,business ,Surgery - Published
- 2018
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7. Nephrometry scores: interobserver reproducibility and perioperative factors prediction
- Author
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C, Moreno-Alarcón, M, Ramírez-Backhaus, P, Pelechano-Gómez, I M, Ortiz-Rodríguez, J, Rubio-Briones, C, Rodríguez-Torreblanca, and E, Solsona-Narbón
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Adult ,Aged, 80 and over ,Observer Variation ,Humans ,Reproducibility of Results ,Middle Aged ,Prognosis ,Nephrectomy ,Kidney Neoplasms ,Aged ,Retrospective Studies - Abstract
To validate the relation of the nephrometry scores in a series of patients who underwent partial nephrectomy with perioperative parameters and the urologist-radiologist reproducibility.A retrospective study of open and laparoscopic partial nephrectomy patients performed between 2005 and 2012 registered in prospective filled out database. An urologist and a radiologist calculated the R.E.N.A.L., PADUA and C-index for 86 patients. We carried out a comparative study of the results using the Spearman and Pearson correlation indexes.Distribution according to the complexity of the tumors with the RENAL calculation was: 42 (49%) low, 35 (41%) moderated and 9 (11%) high complexity. According to PADUA: 35 (41%) low complexity, 32 (37%) intermediate and 19 (22%) high. No statistically significant correlation was found for the appearance of operative complications and the pathology results in case of RENAL and PADUA. A correlation was found in the case of PADUA in relation to the warm ischemia time. Positive correlation according to Spearman's index was found in RENAL, PADUA and C-index between urologist and radiologist evaluations.Nephrometry scores can be a useful tool to plan the surgical technique or approach. However, it is not clear if they are really predictors of surgical or pathologic parameters. The correlation between the urologist and radiologist seems to be sufficient to recommend their use by both specialties.
- Published
- 2013
8. Nefrometrías: reproducibilidad interobservador y predicción de factores perioperatorios
- Author
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Moreno-Alarcón, C., Ramírez-Backhaus, M., Pelechano-Gómez, P., Ortiz-Rodríguez, I.M., Rubio-Briones, J., Rodríguez-Torreblanca, C., and Solsona-Narbón, E.
- Abstract
Validar la relación de las nefrometrías en una serie de pacientes a los que se les realizan nefrectomías parciales con parámetros perioperatorios. Demostrar la reproducibilidad urólogo-radiólogo en cuanto a los resultados de las nefrometrías.
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- 2014
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9. Magnetic resonance imaging as an assessment tool following intervention with an AdVance XP suburethral sling for postprostatectomy urinary incontinence.
- Author
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Collado Serra A, Pelechano Gómez P, Martin I, Dominguez-Escrig J, Alberich-Bayarri Á, Barrios M, Cervera Deval J, and Rubio-Briones J
- Subjects
- Aged, Aged, 80 and over, Humans, Male, Middle Aged, Prospective Studies, Treatment Outcome, Urinary Incontinence etiology, Urinary Incontinence surgery, Magnetic Resonance Imaging, Prostate surgery, Prostatectomy adverse effects, Suburethral Slings, Urinary Incontinence diagnostic imaging
- Abstract
Aims: The aim of this study was to compare magnetic resonance imaging (MRI) parameters in patients with mild incontinence after radical prostatectomy, who had undergone treatment with a suburethral sling. The objective was to compare patients who had been successfully treated with unsuccessful patients., Methods: This observational cohort study at a single institution evaluated consecutive patients treated with an AdVance XP sling. MRI was performed using a 1.5 Tesla system. Preoperative urodynamic assessment and flexible cystoscopy were performed. The qualitative analysis was based on sling indentation (complete vs incomplete). The quantitative analysis comprised the following three parameters: the sling-pubis distance, the thickness of the proximal urethral bulb, and the sling backward distance (SBD), defined as the distance between the prolongation of a line through the major axis of the pubis (the line-segment joining the vertices of the pubis) and the sling indentation. The primary outcome was pad count at 3 months; cure as zero pads. A logistic univariate regression model was employed to assess the potential predictors of successful outcomes. An adjusted multivariate logistic regression model using the significant univariate factors was developed., Results: Of the 83 patients enrolled, the univariate analysis revealed a relationship between failure and adverse urodynamics and between success and sling indentation, thickness of the proximal bulb and SBD. Only the association with SBD persisted in the multivariate analysis., Conclusions: MRI revealed a strong relationship between proper positioning of the sling (small SBD) and continence outcome. These data have important implications for a second surgery following initial sling failure., (© 2019 Wiley Periodicals, Inc.)
- Published
- 2019
- Full Text
- View/download PDF
10. Nephrometry scores: interobserver reproducibility and perioperative factors prediction.
- Author
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Moreno-Alarcón C, Ramírez-Backhaus M, Pelechano-Gómez P, Ortiz-Rodríguez IM, Rubio-Briones J, Rodríguez-Torreblanca C, and Solsona-Narbón E
- Subjects
- Adult, Aged, Aged, 80 and over, Humans, Middle Aged, Observer Variation, Prognosis, Reproducibility of Results, Retrospective Studies, Kidney Neoplasms pathology, Kidney Neoplasms surgery, Nephrectomy
- Abstract
Objectives: To validate the relation of the nephrometry scores in a series of patients who underwent partial nephrectomy with perioperative parameters and the urologist-radiologist reproducibility., Material and Methods: A retrospective study of open and laparoscopic partial nephrectomy patients performed between 2005 and 2012 registered in prospective filled out database. An urologist and a radiologist calculated the R.E.N.A.L., PADUA and C-index for 86 patients. We carried out a comparative study of the results using the Spearman and Pearson correlation indexes., Results: Distribution according to the complexity of the tumors with the RENAL calculation was: 42 (49%) low, 35 (41%) moderated and 9 (11%) high complexity. According to PADUA: 35 (41%) low complexity, 32 (37%) intermediate and 19 (22%) high. No statistically significant correlation was found for the appearance of operative complications and the pathology results in case of RENAL and PADUA. A correlation was found in the case of PADUA in relation to the warm ischemia time. Positive correlation according to Spearman's index was found in RENAL, PADUA and C-index between urologist and radiologist evaluations., Conclusions: Nephrometry scores can be a useful tool to plan the surgical technique or approach. However, it is not clear if they are really predictors of surgical or pathologic parameters. The correlation between the urologist and radiologist seems to be sufficient to recommend their use by both specialties., (Copyright © 2013 AEU. Published by Elsevier Espana. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
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