Search

Your search keyword '"PARAMEDIC trial Collaborators"' showing total 2 results
Start Over Author "PARAMEDIC trial Collaborators"
2 results on '"PARAMEDIC trial Collaborators"'

1. Post-admission outcomes of participants in the PARAMEDIC trial: A cluster randomised trial of mechanical or manual chest compressions.

Author

Ji, C., Lall, R., Quinn, T., Kaye, C., Haywood, K., Horton, J., Gordon, V., Deakin, C.D., Pocock, H., Carson, A., Smyth, M., Rees, N., Han, K., Byers, S., Brace-McDonnell, S., Gates, S., Perkins, G.D., and PARAMEDIC trial Collaborators

Subjects
*ALLIED health personnel, *HOSPITAL admission & discharge, *CRITICAL care medicine, *INTENSIVE care units, *COMPRESSION fractures, *MEDICAL care, *CARDIAC massage, *COMPARATIVE studies, *CARDIOPULMONARY resuscitation, *LENGTH of stay in hospitals, *LONGITUDINAL method, *RESEARCH methodology, *MEDICAL cooperation, *QUALITY of life, *QUESTIONNAIRES, *RESEARCH, *RESEARCH funding, *STATISTICAL sampling, *EVALUATION research, *RANDOMIZED controlled trials, *CASE-control method, *ODDS ratio, *EQUIPMENT & supplies
Abstract

Background: The PARAMEDIC cluster randomised trial evaluated the LUCAS mechanical chest compression device, and did not find evidence that use of mechanical chest compression led to an improvement in survival at 30 days. This paper reports patient outcomes from admission to hospital to 12 months after randomisation.Methods: Information about hospital length of stay and intensive care management was obtained through linkage with Hospital Episode Statistics and the Intensive Care National Audit and Research Centre. Patients surviving to hospital discharge were approached to complete questionnaires (SF-12v2, EQ-5D, MMSE, HADS and PTSD-CL) at 90days and 12 months. The study is registered with Current Controlled Trials, number ISRCTN08233942.Results: 377 patients in the LUCAS arm and 658 patients in the manual chest compression were admitted to hospital. Hospital and intensive care length of stay were similar. Long term follow-up assessments were limited by poor response rates (53.7% at 3 months and 55.6% at 12 months). Follow-up rates were lower in those with worse neurological function. Among respondents, long term health related quality of life outcomes and emotional well-being was similar between groups. Cognitive function, measured by MMSE, was marginally lower in the LUCAS arm mean 26.9 (SD 3.7) compared to control mean 28.0 (SD 2.3), adjusted mean difference -1.5 (95% CI -2.6 to -0.4).Conclusion: There were no clinically important differences identified in outcomes at long term follow-up between those allocated to the mechanical chest compression compared to those receiving manual chest compression. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

2. Post-admission outcomes of participants in the PARAMEDIC trial : a cluster randomised trial of mechanical or manual chest compressions

Author

Michael Smyth, Ranjit Lall, Tom Quinn, Helen Pocock, Samantha J. Brace-McDonnell, Jessica Horton, V Gordon, Gavin D. Perkins, Charles D. Deakin, Sonia Byers, Chen Ji, Nigel Rees, Kirstie L. Haywood, Andrew Carson, Charlotte Kaye, Kyee Han, Simon Gates, and PARAMEDIC trial Collaborators

Subjects
medicine.medical_specialty, Neurological function, alliedhealth, Heart Massage, 030204 cardiovascular system & hematology, Emergency Nursing, Disease cluster, 03 medical and health sciences, 0302 clinical medicine, Intensive care, Surveys and Questionnaires, Hospital discharge, Odds Ratio, Medicine, Humans, Patient Reported Outcome Measures, Prospective Studies, Survivors, National audit, Health related quality of life, business.industry, 030208 emergency & critical care medicine, Compression device, Length of Stay, Cardiopulmonary Resuscitation, otherhospital, Intensive Care Units, Research centre, Case-Control Studies, Emergency medicine, Emergency Medicine, Physical therapy, Quality of Life, Cardiology and Cardiovascular Medicine, business, Out-of-Hospital Cardiac Arrest
Abstract

Background:\ud The PARAMEDIC cluster randomised trial evaluated the LUCAS mechanical chest compression device, and did not find evidence that use of mechanical chest compression led to an improvement in survival at 30 days. This paper reports patient outcomes from admission to hospital to 12 months after randomisation.\ud \ud Methods:\ud Information about hospital length of stay and intensive care management was obtained through linkage with Hospital Episode Statistics and the Intensive Care National Audit and Research Centre. Patients surviving to hospital discharge were approached to complete questionnaires (SF-12v2, EQ-5D, MMSE, HADS and PTSD-CL) at 90 days and 12 months. The study is registered with Current Controlled Trials, number ISRCTN08233942.\ud \ud Results:\ud 377 patients in the LUCAS arm and 658 patients in the manual chest compression were admitted to hospital. Hospital and intensive care length of stay were similar. Long term follow-up assessments were limited by poor response rates (53.7% at 3 months and 55.6% at 12 months). Follow-up rates were lower in those with worse neurological function. Among respondents, long term health related quality of life outcomes and emotional well-being was similar between groups. Cognitive function, measured by MMSE, was marginally lower in the LUCAS arm mean 26.9 (SD 3.7) compared to control mean 28.0 (SD 2.3), adjusted mean difference −1.5 (95% CI −2.6 to −0.4).\ud \ud Conclusion:\ud There were no clinically important differences identified in outcomes at long term follow-up between those allocated to the mechanical chest compression compared to those receiving manual chest compression.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results