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26 results on '"PARSA, NADER"'

4. Design and Rationale for a Randomized, Open-Label, Parallel Clinical Trial Evaluating Major Cardiovascular Events (Pharmacological Treatment Versus Diet Control) in Patients with High-Normal Blood Pressure: The PRINT-TAHA9 Trial

Author

Attar, Armin, primary, Mirhosseini, Seyed Alireza, additional, Borazjani, Roham, additional, Sayadi, Mehrab, additional, Ahadi, Mahsa, additional, Zibaeenezhad, MohammadJavad, additional, Razeghian-Jahromi, Iman, additional, and Parsa, Nader, additional

Published
2024
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5. CAN ANTHROPOMETRIC INDICES PREDICT THE CHANCE OF HYPERTENSION? A MULTICENTRE CROSS-SECTIONAL STUDY IN IRAN

Author

Bazrafshan, Mehdi, primary, Drissi, Hamed Bazrafshan, additional, Akbari-khezrabadi, Ali, additional, Zibaeenezhad, Mohammad Javad, additional, Shojaeefard, Ehsan, additional, Naseri, Arzhang, additional, Mousavi, Shahrokh, additional, Sarejloo, Shirin, additional, Karimi, Mohammadreza, additional, Parsa, Nader, additional, Sayadi, Mehrab, additional, Razeghian-jahromi, Iman, additional, Zibaeenejad, Fatemeh, additional, and Mohammadi, Seyyed Saeed, additional

Published
2024
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9. Can anthropometric indices predict the chance of hypertension? A multicentre cross-sectional study in Iran

Author

Akbari-khezrabadi, Ali, primary, Zibaeenezhad, Mohammad Javad, additional, Shojaeefard, Ehsan, additional, Naseri, Arzhang, additional, Mousavi, Shahrokh, additional, Sarejloo, Shirin, additional, Karimi, Mohammadreza, additional, Hosseinpour, Morteza, additional, Salimi, Maryam, additional, Bazrafshan, Mehdi, additional, Salimi, Amirhossein, additional, Parsa, Nader, additional, Sayadi, Mehrab, additional, Razeghian-Jahromi, Iman, additional, Zibaeenejad, Fatemeh, additional, Mohammadi, Seyyed Saeed, additional, and Bazrafshan Drissi, Hamed, additional

Published
2022
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10. The Prevalence of Cardiovascular Risk Factors in Fatal Cases of COVID-19 in Fars Province, Iran

Author

Zibaeenezhad, Mohammad Javad, Sayadi, Mehrab, Bazrafshan, Hamed, Daneshvar, Zahra, Parsa, Nader, Farshadi, Navid, Hatamnejad, Mohammad Reza, Bazrafshan, Mehdi, Estedlal, Alireza, Khademalizade, Mehran, Zarenezhad, Mohammad, Elyaspour, Zahra, and Razeghian-Jahromi, Iman

Subjects
Cardiovascular Disease, COVID-19, Comorbidity, Cardiovascular Risk Factor
Abstract

Human health has been challenged drastically by the emergence of COVID-19. This pandemic has imposed a serious burden on different aspects of life. Apart from the high rates of morbidity and mortality, reporting of newly formed variants with enhanced contagious capacity has made the future vague. Existence of different comorbidities is a prominent factor towards poor prognosis and fatal outcomes. Objectives: The present study aimed to identify the most important comorbidities in the COVID-19 patients who passed away during the first wave in Fars province, Iran. Methods: Trained general physicians obtained data from medical files in the referral hospitals of COVID-19 throughout the province. These included demographic data, past medical history, and existence of comorbidities. The data were analyzed using chi-square test, independent sample t-test, and Mann-Whitney test. P-values less than 0.05 were considered statistically significant. Results: Out of the 3700 confirmed cases, 87 patients died from February to May 2020. Among these patients, 81.1% had comorbidities, with hypertension, diabetes, and cardiovascular disease being the most prevalent ones. The results revealed no significant differences between the individuals with and without comorbidities regarding age, gender, and duration of ICU hospitalization. Oxygen saturation was also poor in both groups. However, the patients with comorbidities had significantly higher blood urea nitrogen and creatinine levels compared to their comorbidity-free peers. Conclusions: Cardiovascular disease and the related risk factors contributed greatly to the deadly fate in COVID-19 patients. Hence, early prophylactic and therapeutic interventions should be considered in COVID-19 patients harboring such comorbidities. This can play a pivotal role in reducing the rate of mortality and the consequent financial and social harms.

Published
2022
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17. Analysing cardiovascular risk factors and related outcomes in a middle-aged to older adults population in Iran: a cohort protocol of the Shiraz Heart Study (SHS)

Author

Zibaeenezhad, Mohammad Javad, primary, Ghaem, Haleh, additional, Parsa, Nader, additional, Sayadi, Mehrab, additional, Askarian, Mehrdad, additional, Kasaei, Mohammad, additional, Sohrabi, Zahra, additional, Dehghani-Firouzabadi, Azime, additional, Nariman, Ali, additional, Radmanesh, Salma, additional, Mani, Arya, additional, Bahramali, Ehsan, additional, Nikoo, Mohammad Hossein, additional, Moaref, Ali Reza, additional, and Razeghian-Jahromi, Iman, additional

Published
2019
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18. The Prevalence of Cardiovascular Risk Factors in Fatal Cases of COVID-19 in Fars Province, Iran.

Author

Zibaeenezhad, Mohammad Javad, Sayadi, Mehrab, Bazrafshan, Hamed, Daneshvar, Zahra, Parsa, Nader, Farshadi, Navid, Hatamnejad, Mohammad Reza, Bazrafshan, Mehdi, Estedlal, Alireza, Khademalizade, Mehran, Zarenezhad, Mohammad, Elyaspour, Zahra, and Razeghian-Jahromi, Iman

Subjects
MATHEMATICAL variables, T-test (Statistics), STATISTICAL significance, CREATININE, SCIENTIFIC observation, HYPERTENSION, SEX distribution, HOSPITAL care, CARDIOVASCULAR diseases risk factors, RETROSPECTIVE studies, DISEASE prevalence, CHI-squared test, MANN Whitney U Test, AGE distribution, BLOOD urea nitrogen, DESCRIPTIVE statistics, MEDICAL records, ACQUISITION of data, INTENSIVE care units, DATA analysis software, COVID-19 pandemic, COVID-19, COMORBIDITY, DIABETES
Abstract

Background: Human health has been challenged drastically by the emergence of COVID-19. This pandemic has imposed a serious burden on different aspects of life. Apart from the high rates of morbidity and mortality, reporting of newly formed variants with enhanced contagious capacity has made the future vague. Existence of different comorbidities is a prominent factor towards poor prognosis and fatal outcomes. Objectives: The present study aimed to identify the most important comorbidities in the COVID-19 patients who passed away during the first wave in Fars province, Iran. Methods: Trained general physicians obtained data from medical files in the referral hospitals of COVID-19 throughout the province. These included demographic data, past medical history, and existence of comorbidities. The data were analyzed using chi-square test, independent sample t-test, and Mann-Whitney test. P-values less than 0.05 were considered statistically significant. Results: Out of the 3700 confirmed cases, 87 patients died from February to May 2020. Among these patients, 81.1% had comorbidities, with hypertension, diabetes, and cardiovascular disease being the most prevalent ones. The results revealed no significant differences between the individuals with and without comorbidities regarding age, gender, and duration of ICU hospitalization. Oxygen saturation was also poor in both groups. However, the patients with comorbidities had significantly higher blood urea nitrogen and creatinine levels compared to their comorbidity-free peers. Conclusions: Cardiovascular disease and the related risk factors contributed greatly to the deadly fate in COVID-19 patients. Hence, early prophylactic and therapeutic interventions should be considered in COVID-19 patients harboring such comorbidities. This can play a pivotal role in reducing the rate of mortality and the consequent financial and social harms. [ABSTRACT FROM AUTHOR]

Published
2021

25. Abstract 554: The Association Of Multiple Variants In The TNXBGene With Vascular Aneurysms And Dissections

Author

Neogi, Arpita, Towne, Meghan, Dykas, Daniel, Parsa, Nader, Attar, Armin, FATHZADEH, MOHSEN, Bale, Allen, and Mani, Arya

Abstract

Pathogenic variants in the Tenascin-XB (TNXB)gene are associated with autosomal recessive Ehlers Danlos Syndrome (classical-like). Here, we report the association of two or more TNXBvariants with aneurysms and/or dissections in different arterial beds. We compared case and control data from exome sequencing (ES) or multigene panel testing (MGPT). Statistical analysis was performed by Fisher’s exact test. From 350 cases of vascular aneurysm and/or dissection referred for genetic testing by ES, we identified 5 individuals with two or more rare missense variants in the TNXBgene (1.4%) versus 16 individuals with two or more TNXBvariants from 10, 968 matched controls (0.14%, p<.0.01). In a replication cohort of 1844 individuals undergoing multigene panel testing (MGPT) for connective tissue disorders including aneurysms and dissections, we identified 27 individuals with two or more TNXBvariants (1.5%, p<0.01); 19 of these individuals (70.3%, n= 19/27) had a personal history of aneurysm and/or dissection and had no other identifiable pathogenic or likely pathogenic variants. Interestingly, 3 (15.7%, n=3/19) had a diagnosis of bicuspid aortic valve (BAV), a 10-fold higher prevalence compared to the general population incidence of BAV. An additional 158 individuals with BAV who underwent ES also showed a higher prevalence of multiple TNXBvariants compared to controls (1.8% vs 0.14%, p<0.01). This data strongly supports an association between multiple TNXBvariants and vascular aneurysms and dissections.

Published
2022
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26. Depression, testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV infection.

Author

Lari, Mahmood Amini, Faramarz, Hosain, Shams, Mesbah, MarzbanA, Maryam, and Parsa, Nader

Subjects
HIV infections, HYPOGONADISM
Abstract

An abstract of the article "Depression, testosterone concentration, sexual dysfunction and methadone use among men with hypogonadism and HIV infection," by Mahmood Amini Lari, Hosain Faramarz, Mesbah Shams, Maryam MarzbanA, and Nader Parsa is presented.

Published
2012
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