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Your search keyword '"PDE5/6 inhibitor"' showing total 2 results
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2 results on '"PDE5/6 inhibitor"'

1. Central serous chorioretinopathy treatment with a systemic PDE5 and PDE6 inhibitor (sildenafil)

Author

D. Jackson Coleman, Winston Lee, Suzanne Daly, Mark P. Breazzano, Janet Sparrow, and Stephen H. Tsang

Subjects
PDE5/6 inhibitor, Sildenafil, Central serous chorioretinopathy, Ophthalmology, RE1-994
Abstract

Purpose: Examine the use of systemic phosphodiesterase inhibition (sildenafil) to clear central serous chorioretinopathy (CSCR). Observations: In a long-standing CSCR patient, sildenafil produced a rapid resolution. When discontinued (dechallenge) the CSCR returned. When rechallenged, the CSCR again rapidly disappeared and did not recur in 5 months of continued therapy. Conclusions: AND IMPORTANCE: Systemic sildenafil can cause rapid clearance of CSCR and can augment or replace other treatments.

Published
2021
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2. Central serous chorioretinopathy treatment with a systemic PDE5 and PDE6 inhibitor (sildenafil)

Author

Winston Lee, Mark P. Breazzano, Stephen H. Tsang, Suzanne Daly, Janet R. Sparrow, and D. Jackson Coleman

Subjects
medicine.medical_specialty, business.industry, Sildenafil, Central serous chorioretinopathy, Urology, Case Report, Phosphodiesterase inhibition, respiratory tract diseases, Ophthalmology, chemistry.chemical_compound, Serous fluid, lcsh:Ophthalmology, chemistry, lcsh:RE1-994, cardiovascular system, Medicine, business, PDE5/6 inhibitor, Dechallenge
Abstract

Purpose Examine the use of systemic phosphodiesterase inhibition (sildenafil) to clear central serous chorioretinopathy (CSCR). Observations In a long-standing CSCR patient, sildenafil produced a rapid resolution. When discontinued (dechallenge) the CSCR returned. When rechallenged, the CSCR again rapidly disappeared and did not recur in 5 months of continued therapy. Conclusions AND IMPORTANCE: Systemic sildenafil can cause rapid clearance of CSCR and can augment or replace other treatments.

Published
2020

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