1. ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma
- Author
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Tjalling Bosse, David Cibula, Xavier Matias-Guiu, Anneke M. Westermann, Philippe Morice, Remi A. Nout, Christian Marth, Domenica Lorusso, Mansoor Raza Mirza, Jalid Sehouli, Alexandra Taylor, Antonio González-Martín, Pauline Wimberger, François Planchamp, Maria Rosaria Raspollini, Simone Marnitz, Jonathan A. Ledermann, Sigurd Lax, Denis Querleu, Christina Fotopoulou, Cyrus Chargari, Nicole Concin, Carien L. Creutzberg, Anna Fagotti, Alina Sturdza, Nicoletta Colombo, Dearbhaile E. O’Donnell, Ignace Vergote, Oncology, CCA -Cancer Center Amsterdam, Concin, N, Matias-Guiu, X, Vergote, I, Cibula, D, Mirza, M, Marnitz, S, Ledermann, J, Bosse, T, Chargari, C, Fagotti, A, Fotopoulou, C, Gonzalez Martin, A, Lax, S, Lorusso, D, Marth, C, Morice, P, Nout, R, O'Donnell, D, Querleu, D, Raspollini, M, Sehouli, J, Sturdza, A, Taylor, A, Westermann, A, Wimberger, P, Colombo, N, Planchamp, F, Creutzberg, C, and Radiotherapy
- Subjects
0301 basic medicine ,Staging ,Palliative treatment ,Endometrium--Cancer ,Biopsy ,Diseases--Risk factors ,Medical Oncology ,030218 nuclear medicine & medical imaging ,Scientific evidence ,DEEP MYOMETRIAL INVASION ,surgery ,Risk groups ,0302 clinical medicine ,Endometrial cancer ,Multidisciplinary approach ,Risk Factors ,MINIMALLY-INVASIVE SURGERY ,Fertility preservation ,Evidence-Based Medicine ,030219 obstetrics & reproductive medicine ,Factors de risc en les malalties ,FERTILITY-PRESERVING TREATMENT ,Gynaecological oncology ,Consensus conference ,Obstetrics and Gynecology ,Obstetrics & Gynecology ,General Medicine ,Hematology ,Patologia ,Management ,Europe ,Treatment Outcome ,Molecular Diagnostic Techniques ,Oncology ,LYMPH-NODE BIOPSY ,030220 oncology & carcinogenesis ,Female ,Life Sciences & Biomedicine ,medicine.medical_specialty ,RATE INTERSTITIAL BRACHYTHERAPY ,PHASE-II EVALUATION ,Consensus ,Genital Neoplasms, Female ,Planificació sanitària ,Guidelines as Topic ,Endometrial carcinoma ,Guidelines ,Risk Assessment ,uterine cancer ,Pathology and Forensic Medicine ,03 medical and health sciences ,Predictive Value of Tests ,Uterine cancer ,Preoperative Care ,Biomarkers, Tumor ,Recurrent disease ,Carcinoma ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Quality of care ,Molecular Biology ,Neoplasm Staging ,TOTAL LAPAROSCOPIC HYSTERECTOMY ,Science & Technology ,Endometri--Càncer ,business.industry ,EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY ,General surgery ,LONG-TERM SURVIVAL ,Molecular markers ,Cell Biology ,medicine.disease ,Endometrial Neoplasms ,radiation ,030104 developmental biology ,Settore MED/40 - GINECOLOGIA E OSTETRICIA ,EXTERNAL-BEAM RADIOTHERAPY ,Càncer d'endometri ,Family medicine ,Radiation Oncology ,Health planning ,pathology ,business - Abstract
A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide. ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of endometrial carcinoma (27 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2014, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 191 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover endometrial carcinoma staging, definition of prognostic risk groups integrating molecular markers, pre- and intra-operative work-up, fertility preservation, management for early, advanced, metastatic, and recurrent disease and palliative treatment. Principles of radiotherapy and pathological evaluation are also defined.
- Published
- 2021