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217 results on '"PI3K, Phosphoinositide 3-kinase"'

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1. Discovery of novel selective PI3Kγ inhibitors through combining machine learning-based virtual screening with multiple protein structures and bio-evaluation

2. The roles and potential therapeutic implications of C5a in the pathogenesis of COVID-19-associated coagulopathy

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3. Glycolysis-induced drug resistance in tumors—A response to danger signals?

4. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants

5. Major flavonoids from Psiadia punctulata produce vasodilation via activation of endothelial dependent NO signaling

6. Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy

7. Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis

8. Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan

9. PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging

10. SWELL1 promotes cell growth and metastasis of hepatocellular carcinoma in vitro and in vivo

11. Neutrophils: Homing in on the myeloid mechanisms of metastasis

12. Psoriasiform eruptions secondary to phosphoinositide 3-kinase inhibition

13. In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate

14. Nuclear Phosphatidylinositol 3,4,5-Trisphosphate Interactome Uncovers an Enrichment in Nucleolar Proteins

15. Expression of Concern: MicroRNA-34A inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expression

16. Dissecting lipid metabolism alterations in SARS-CoV-2

17. Platelet transfusion for cancer secondary thrombocytopenia: Platelet and cancer cell interaction

18. A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners

25. Traditional Chinese Medicine (TCM) in the treatment of viral infections: Efficacies and mechanisms

26. The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure

27. Signaling roles of phosphoinositides in the retina

28. Does the proteasome inhibitor bortezomib sensitize to DNA- damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? - A preclinical assessment in vitro and in vivo

32. mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition

33. An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14

34. The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach

35. Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases

36. Design, synthesis and biological evaluation of pyrazolo[3,4

37. Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential

38. Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats

39. Anticancer activity of THMPP : Downregulation of PI3K/ S6K1 in breast cancer cell line

40. Effect of Korean Red Ginseng on metabolic syndrome

41. Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis

42. Jing Si Herbal Drink as a prospective adjunctive therapy for COVID-19 treatment: Molecular evidence and mechanisms

43. Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

44. Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications

45. Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara

46. Designer Approaches for G Protein–Coupled Receptor Modulation for Cardiovascular Disease

47. eIF4E Phosphorylation in Prostate Cancer

48. The role of autophagy in survival response induced by 27-hydroxycholesterol in human promonocytic cells

49. Epidermodysplasia verruciformis in a young adult with activated PI3Kδ syndrome

50. The metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer