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2. Decreased ATM Protein Expression Is Substantiated with PTEN Loss in Defining Aggressive Phenotype of Prostate Cancer Associated with Lethal Disease

Author

Walker, Simon R, Abdelsalam, Ramy, Ghosh, Sunita, Livingstone, Julie, Palanisamy, Nallasivam, Boutros, Paul C, Yip, Steven M, Lees-Miller, Susan P, and Bismar, Tarek A

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Aging, Cancer, Genetics, Rare Diseases, Neurosciences, Prostate Cancer, Urologic Diseases, Ataxia Telangiectasia, Neurodegenerative, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, Good Health and Well Being, ATM, PTEN, ERG, Protein expression, Immunohistochemistry, Gleason score, Poly-ADP ribose polymerase and, ATR inhibitors, Androgen deprivation therapy, Cancer-specific mortality, Overall survival, Poly-ADP ribose polymerase and ATR inhibitors, Urology & Nephrology, Clinical sciences
Abstract

BackgroundAtaxia Telangiectasia Mutated (ATM) serine/threonine protein kinase is a known tumor suppressor, involved in DNA damage repair. It has prognostic and predictive therapeutic implications and is associated with aggressive prostate cancer (PCa).ObjectiveTo investigate the prognostic value of ATM protein expression in PCa patients and assessed the combined value of ATM, ERG, and PTEN status.Design setting and participantsThis study consisted of 303 patients with incidental, locally advanced, and castrate-resistant PCa by transurethral resection of the prostate (TURP).Outcome measurements and statistical analysisTURP samples from 303 PCa patients were assessed by immunohistochemistry (IHC for ATM, ERG, and PTEN. Individual and combined marker status were correlated with International Society of Urological Pathology Gleason grade group, overall survival (OS), and PCa-specific mortality (PCSM).Results and limitationsDecreased ATM expression (negative/weak intensity) occurred in 164/303 (54.1%) patients, and was associated with shorter OS and higher PCSM (p = 0.015 and p = 0.001, respectively). Negative/weak ATM expression was significantly associated with PCSM with a hazard ratio of 2.09 (95% confidence interval 1.34-3.27, p = 0.001). Assessment of Combined ATM/PTEN expression showed improved prognostic power to predict OS and PCSM, independent of Gleason grade groups.ConclusionsDecreased ATM protein expression is associated with poor outcomes in advanced PCa patients. Patients with combined low ATM/PTEN negative expression are at the highest risk for reduced OS and PCSM. Assessing the combined status of ATM/PTEN by IHC in PCa patients may aid in risk stratification relative to OS and PCSM. Moreover, since ATM plays an integral role in DNA damage response pathways, future studies will enhance our understanding of how outcomes of patients with altered ATM and PTEN expression can be improved further with poly-ADP ribose polymerase inhibitors (PARPi), combinations of PARPi and androgen receptor-targeted therapies, as well as platinum-based chemotherapies.Patient summaryLower ATM intensity is associated with increased cancer-specific mortality in prostate cancer patients. Patients with lower ATM and PTEN negative expression showed decreased overall survival and increased cancer mortality compared with controls.

Published
2021

3. Copy Number Profiles of Prostate Cancer in Men of Middle Eastern Ancestry.

Author

Albawardi, Alia, Livingstone, Julie, Almarzooqi, Saeeda, Palanisamy, Nallasivam, Houlahan, Kathleen E, Awwad, Aktham Adnan Ahmad, Abdelsalam, Ramy A, Boutros, Paul C, and Bismar, Tarek A

Subjects
copy number aberrations, middle eastern ancestry, prostate cancer, Aging, Genetics, Human Genome, Prostate Cancer, Cancer, Urologic Diseases, Biotechnology, Oncology and Carcinogenesis
Abstract

Our knowledge of prostate cancer (PCa) genomics mainly reflects European (EUR) and Asian (ASN) populations. Our understanding of the influence of Middle Eastern (ME) and African (AFR) ancestry on the mutational profiles of prostate cancer is limited. To characterize genomic differences between ME, EUR, ASN, and AFR ancestry, fluorescent in situ hybridization (FISH) studies for NKX3-1 deletion and MYC amplification were carried out on 42 tumors arising in individuals of ME ancestry. These were supplemented by analysis of genome-wide copy number profiles of 401 tumors of all ancestries. FISH results of NKX3-1 and MYC were assessed in the ME cohort and compared to other ancestries. Gene level copy number aberrations (CNAs) for each sample were statistically compared between ancestry groups. NKX3-1 deletions by FISH were observed in 17/42 (17.5%) prostate tumors arising in men of ME ancestry, while MYC amplifications were only observed in 1/42 (2.3%). Using CNAs called from arrays, the incidence of NKX3-1 deletions was significantly lower in ME vs. other ancestries (20% vs. 52%; p = 2.3 × 10-3). Across the genome, tumors arising in men of ME ancestry had fewer CNAs than those in men of other ancestries (p = 0.014). Additionally, the somatic amplification of 21 specific genes was more frequent in tumors arising in men of ME vs. EUR ancestry (two-sided proportion test; Q < 0.05). Those included amplifications in the glutathione S-transferase family on chromosome 1 (GSTM1, GSTM2, GSTM5) and the IQ motif-containing family on chromosome 3 (IQCF1, IQCF2, IQCF13, IQCF4, IQCF5, IQCF6). Larger studies investigating ME populations are warranted to confirm these observations.

Published
2021

9. Cultured circulating tumor cells and their derived xenografts for personalized oncology.

Author

Wang, Ruoxiang, Chu, Gina CY, Mrdenovic, Stefan, Annamalai, Alagappan A, Hendifar, Andrew E, Nissen, Nicholas N, Tomlinson, James S, Lewis, Michael, Palanisamy, Nallasivam, Tseng, Hsian-Rong, Posadas, Edwin M, Freeman, Michael R, Pandol, Stephen J, Zhau, Haiyen E, and Chung, Leland WK

Subjects
Cancer metastasis, Circulating tumor cell, Peripheral blood, ex vivo culture
Abstract

Recent cancer research has demonstrated the existence of circulating tumor cells (CTCs) in cancer patient's blood. Once identified, CTC biomarkers will be invaluable tools for clinical diagnosis, prognosis and treatment. In this review, we propose ex vivo culture as a rational strategy for large scale amplification of the limited numbers of CTCs from a patient sample, to derive enough CTCs for accurate and reproducible characterization of the biophysical, biochemical, gene expressional and behavioral properties of the harvested cells. Because of tumor cell heterogeneity, it is important to amplify all the CTCs in a blood sample for a comprehensive understanding of their role in cancer metastasis. By analyzing critical steps and technical issues in ex vivo CTC culture, we developed a cost-effective and reproducible protocol directly culturing whole peripheral blood mononuclear cells, relying on an assumed survival advantage in CTCs and CTC-like cells over the normal cells to amplify this specified cluster of cancer cells.

Published
2016

10. Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low‐risk patient as defined by targeted sequencing

Author

Tillman, Brittny N, Yanik, Megan, Birkeland, Andrew C, Liu, Chia-Jen, Hovelson, Daniel H, Cani, Andi K, Palanisamy, Nallasivam, Carskadon, Shannon, Carey, Thomas E, Bradford, Carol R, Tomlins, Scott A, McHugh, Jonathan B, Spector, Matthew E, and Brenner, J Chad

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Human Genome, Genetics, Rare Diseases, Clinical Research, Cancer, Dental/Oral and Craniofacial Disease, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Carcinoma, Squamous Cell, Class I Phosphatidylinositol 3-Kinases, DNA Copy Number Variations, DNA Mutational Analysis, Female, Fibroblast Growth Factors, Gene Expression Regulation, Neoplastic, Head and Neck Neoplasms, High-Throughput Nucleotide Sequencing, Humans, Middle Aged, Neoplasm Recurrence, Local, amplification, fibroblast growth factor, fibroblast growth factor receptor, head and neck squamous cell carcinoma, mutant, Dentistry, Otorhinolaryngology, Clinical sciences
Abstract

BackgroundTargeted sequencing of patients with epidemiologically low-risk (ELR) head and neck squamous cell carcinoma (HNSCC) could help identify novel drivers or lost suppressors leading to precision medicine protocols and improved survival rates.MethodsA patient with ELR-HNSCC was selected for targeted sequencing. We then assessed next generation sequencing cohorts from the Oncomine Powertool Database, which contains pan-cancer data from The Cancer Genome Atlas (TCGA).ResultsTargeted sequencing revealed fibroblast growth factor receptor-1 (FGFR1) amplifications as a putative driver of the patient's tumor. Patients with HNSCC from TCGA data demonstrated fibroblast growth factor (FGF) family mutations, rearrangements, or amplifications in over 35% of HNSCC cases, with a statistically significant higher frequency in African American populations. FGF alterations were unique from activating phosphatidylinositol 3-kinase (PIK3CA) mutations.ConclusionTogether, these data suggest that FGF signaling may be critical for a subset of patients with HNSCC independent of other known pathways and provides rationale for leveraging patients with ELR-HNSCC to define molecular subsets of high-risk HNSCC. © 2016 Wiley Periodicals, Inc. Head Neck 38: E1646-E1652, 2016.

Published
2016

13. Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer

Author

Chakravarthi, Balabhadrapatruni VSK, Dedigama-Arachchige, Pavithra, Carskadon, Shannon, Sundaram, Shanker Kalyana, Li, Jia, Wu, Kuan-Han Hank, Chandrashekar, Darshan Shimoga, Peabody, James O, Stricker, Hans, Hwang, Clara, Chitale, Dhananjay A, Williamson, Sean R, Gupta, Nilesh S, Navone, Nora M, Rogers, Craig, Menon, Mani, Varambally, Sooryanarayana, and Palanisamy, Nallasivam

Published
2019
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15. Role of Adenosine Deaminase in Prostate Cancer Progression

Author

Charles, Christy, primary, Lloyd, Stacy M, additional, Piyarathna, Danthasinghe Waduge Badrajee, additional, Gohlke, Jie, additional, Rasaily, Uttam, additional, Putluri, Vasanta, additional, Simons, Brian W, additional, Zaslavsky, Alexander, additional, Nallandhighal, Srinivas, additional, Palanisamy, Nallasivam, additional, Navone, Nora, additional, Jones, Jeffrey A, additional, Ittmann, Michael M, additional, Putluri, Nagireddy, additional, Rowley, David R, additional, Salami, Simpa S, additional, Palapattu, Ganesh, additional, and Sreekumar, Arun, additional

Published
2023
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25. Data from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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26. Data from CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation

Author

Rasool, Reyaz ur, primary, Natesan, Ramakrishnan, primary, Deng, Qu, primary, Aras, Shweta, primary, Lal, Priti, primary, Sander Effron, Samuel, primary, Mitchell-Velasquez, Erick, primary, Posimo, Jessica M., primary, Carskadon, Shannon, primary, Baca, Sylvan C., primary, Pomerantz, Mark M., primary, Siddiqui, Javed, primary, Schwartz, Lauren E., primary, Lee, Daniel J., primary, Palanisamy, Nallasivam, primary, Narla, Goutham, primary, Den, Robert B., primary, Freedman, Matthew L., primary, Brady, Donita C., primary, and Asangani, Irfan A., primary

Published
2023
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27. Supplementary Methods and Data (posted 7/5/2011) from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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28. Supplementary Data from CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation

Author

Rasool, Reyaz ur, primary, Natesan, Ramakrishnan, primary, Deng, Qu, primary, Aras, Shweta, primary, Lal, Priti, primary, Sander Effron, Samuel, primary, Mitchell-Velasquez, Erick, primary, Posimo, Jessica M., primary, Carskadon, Shannon, primary, Baca, Sylvan C., primary, Pomerantz, Mark M., primary, Siddiqui, Javed, primary, Schwartz, Lauren E., primary, Lee, Daniel J., primary, Palanisamy, Nallasivam, primary, Narla, Goutham, primary, Den, Robert B., primary, Freedman, Matthew L., primary, Brady, Donita C., primary, and Asangani, Irfan A., primary

Published
2023
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29. Supplementary Methods, Figures, Tables, and References from Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Author

Wang, Xiao-Song, primary, Shankar, Sunita, primary, Dhanasekaran, Saravana M., primary, Ateeq, Bushra, primary, Sasaki, Atsuo T., primary, Jing, Xiaojun, primary, Robinson, Daniel, primary, Cao, Qi, primary, Prensner, John R., primary, Yocum, Anastasia K., primary, Wang, Rui, primary, Fries, Daniel F., primary, Han, Bo, primary, Asangani, Irfan A., primary, Cao, Xuhong, primary, Li, Yong, primary, Omenn, Gilbert S., primary, Pflueger, Dorothee, primary, Gopalan, Anuradha, primary, Reuter, Victor E., primary, Kahoud, Emily Rose, primary, Cantley, Lewis C., primary, Rubin, Mark A., primary, Palanisamy, Nallasivam, primary, Varambally, Sooryanarayana, primary, and Chinnaiyan, Arul M., primary

Published
2023
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35. Supplementary Table 2 from Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay

Author

Wang, Lisha, primary, Harms, Paul W., primary, Palanisamy, Nallasivam, primary, Carskadon, Shannon, primary, Cao, Xuhong, primary, Siddiqui, Javed, primary, Patel, Rajiv M., primary, Zelenka-Wang, Sylvia, primary, Durham, Alison B., primary, Fullen, Douglas R., primary, Harms, Kelly L., primary, Su, Fengyun, primary, Shukla, Sudhanshu, primary, Mehra, Rohit, primary, and Chinnaiyan, Arul M., primary

Published
2023
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36. SFigure S1 from Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay

Author

Wang, Lisha, primary, Harms, Paul W., primary, Palanisamy, Nallasivam, primary, Carskadon, Shannon, primary, Cao, Xuhong, primary, Siddiqui, Javed, primary, Patel, Rajiv M., primary, Zelenka-Wang, Sylvia, primary, Durham, Alison B., primary, Fullen, Douglas R., primary, Harms, Kelly L., primary, Su, Fengyun, primary, Shukla, Sudhanshu, primary, Mehra, Rohit, primary, and Chinnaiyan, Arul M., primary

Published
2023
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37. Supplementary Data from HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone

Author

Day, Kathleen C., primary, Hiles, Guadalupe Lorenzatti, primary, Kozminsky, Molly, primary, Dawsey, Scott J., primary, Paul, Alyssa, primary, Broses, Luke J., primary, Shah, Rajal, primary, Kunja, Lakshmi P., primary, Hall, Christopher, primary, Palanisamy, Nallasivam, primary, Daignault-Newton, Stephanie, primary, El-Sawy, Layla, primary, Wilson, Steven James, primary, Chou, Andrew, primary, Ignatoski, Kathleen Woods, primary, Keller, Evan, primary, Thomas, Dafydd, primary, Nagrath, Sunitha, primary, Morgan, Todd, primary, and Day, Mark L., primary

Published
2023
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38. Table S2 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Author

Palanisamy, Nallasivam, primary, Yang, Jun, primary, Shepherd, Peter D.A., primary, Li-Ning-Tapia, Elsa M., primary, Labanca, Estefania, primary, Manyam, Ganiraju C., primary, Ravoori, Murali K., primary, Kundra, Vikas, primary, Araujo, John C., primary, Efstathiou, Eleni, primary, Pisters, Louis L., primary, Wan, Xinhai, primary, Wang, Xuemei, primary, Vazquez, Elba S., primary, Aparicio, Ana M., primary, Carskadon, Shannon L., primary, Tomlins, Scott A., primary, Kunju, Lakshmi P., primary, Chinnaiyan, Arul M., primary, Broom, Bradley M., primary, Logothetis, Christopher J., primary, Troncoso, Patricia, primary, and Navone, Nora M., primary

Published
2023
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39. Supplementary Data from Virus-positive Merkel Cell Carcinoma Is an Independent Prognostic Group with Distinct Predictive Biomarkers

Author

Harms, Kelly L., primary, Zhao, Lili, primary, Johnson, Bryan, primary, Wang, Xiaoming, primary, Carskadon, Shannon, primary, Palanisamy, Nallasivam, primary, Rhodes, Daniel R., primary, Mannan, Rahul, primary, Vo, Josh N., primary, Choi, Jae Eun, primary, Chan, May P., primary, Fullen, Douglas R., primary, Patel, Rajiv M., primary, Siddiqui, Javed, primary, Ma, Vincent T., primary, Hrycaj, Steven, primary, McLean, Scott A., primary, Hughes, Tasha M., primary, Bichakjian, Christopher K., primary, Tomlins, Scott A., primary, and Harms, Paul W., primary

Published
2023
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40. Legend of Supplementary Figures from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Author

Palanisamy, Nallasivam, primary, Yang, Jun, primary, Shepherd, Peter D.A., primary, Li-Ning-Tapia, Elsa M., primary, Labanca, Estefania, primary, Manyam, Ganiraju C., primary, Ravoori, Murali K., primary, Kundra, Vikas, primary, Araujo, John C., primary, Efstathiou, Eleni, primary, Pisters, Louis L., primary, Wan, Xinhai, primary, Wang, Xuemei, primary, Vazquez, Elba S., primary, Aparicio, Ana M., primary, Carskadon, Shannon L., primary, Tomlins, Scott A., primary, Kunju, Lakshmi P., primary, Chinnaiyan, Arul M., primary, Broom, Bradley M., primary, Logothetis, Christopher J., primary, Troncoso, Patricia, primary, and Navone, Nora M., primary

Published
2023
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41. Supplementary Figure S2 from HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone

Author

Day, Kathleen C., primary, Hiles, Guadalupe Lorenzatti, primary, Kozminsky, Molly, primary, Dawsey, Scott J., primary, Paul, Alyssa, primary, Broses, Luke J., primary, Shah, Rajal, primary, Kunja, Lakshmi P., primary, Hall, Christopher, primary, Palanisamy, Nallasivam, primary, Daignault-Newton, Stephanie, primary, El-Sawy, Layla, primary, Wilson, Steven James, primary, Chou, Andrew, primary, Ignatoski, Kathleen Woods, primary, Keller, Evan, primary, Thomas, Dafydd, primary, Nagrath, Sunitha, primary, Morgan, Todd, primary, and Day, Mark L., primary

Published
2023
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42. Figure S7 from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Author

Palanisamy, Nallasivam, primary, Yang, Jun, primary, Shepherd, Peter D.A., primary, Li-Ning-Tapia, Elsa M., primary, Labanca, Estefania, primary, Manyam, Ganiraju C., primary, Ravoori, Murali K., primary, Kundra, Vikas, primary, Araujo, John C., primary, Efstathiou, Eleni, primary, Pisters, Louis L., primary, Wan, Xinhai, primary, Wang, Xuemei, primary, Vazquez, Elba S., primary, Aparicio, Ana M., primary, Carskadon, Shannon L., primary, Tomlins, Scott A., primary, Kunju, Lakshmi P., primary, Chinnaiyan, Arul M., primary, Broom, Bradley M., primary, Logothetis, Christopher J., primary, Troncoso, Patricia, primary, and Navone, Nora M., primary

Published
2023
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43. Figure S3 from Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay

Author

Wang, Lisha, primary, Harms, Paul W., primary, Palanisamy, Nallasivam, primary, Carskadon, Shannon, primary, Cao, Xuhong, primary, Siddiqui, Javed, primary, Patel, Rajiv M., primary, Zelenka-Wang, Sylvia, primary, Durham, Alison B., primary, Fullen, Douglas R., primary, Harms, Kelly L., primary, Su, Fengyun, primary, Shukla, Sudhanshu, primary, Mehra, Rohit, primary, and Chinnaiyan, Arul M., primary

Published
2023
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44. Supplementary Table 1 from Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay

Author

Wang, Lisha, primary, Harms, Paul W., primary, Palanisamy, Nallasivam, primary, Carskadon, Shannon, primary, Cao, Xuhong, primary, Siddiqui, Javed, primary, Patel, Rajiv M., primary, Zelenka-Wang, Sylvia, primary, Durham, Alison B., primary, Fullen, Douglas R., primary, Harms, Kelly L., primary, Su, Fengyun, primary, Shukla, Sudhanshu, primary, Mehra, Rohit, primary, and Chinnaiyan, Arul M., primary

Published
2023
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45. Supplementary Methods from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Author

Palanisamy, Nallasivam, primary, Yang, Jun, primary, Shepherd, Peter D.A., primary, Li-Ning-Tapia, Elsa M., primary, Labanca, Estefania, primary, Manyam, Ganiraju C., primary, Ravoori, Murali K., primary, Kundra, Vikas, primary, Araujo, John C., primary, Efstathiou, Eleni, primary, Pisters, Louis L., primary, Wan, Xinhai, primary, Wang, Xuemei, primary, Vazquez, Elba S., primary, Aparicio, Ana M., primary, Carskadon, Shannon L., primary, Tomlins, Scott A., primary, Kunju, Lakshmi P., primary, Chinnaiyan, Arul M., primary, Broom, Bradley M., primary, Logothetis, Christopher J., primary, Troncoso, Patricia, primary, and Navone, Nora M., primary

Published
2023
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46. Data from HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone

Author

Day, Kathleen C., primary, Hiles, Guadalupe Lorenzatti, primary, Kozminsky, Molly, primary, Dawsey, Scott J., primary, Paul, Alyssa, primary, Broses, Luke J., primary, Shah, Rajal, primary, Kunja, Lakshmi P., primary, Hall, Christopher, primary, Palanisamy, Nallasivam, primary, Daignault-Newton, Stephanie, primary, El-Sawy, Layla, primary, Wilson, Steven James, primary, Chou, Andrew, primary, Ignatoski, Kathleen Woods, primary, Keller, Evan, primary, Thomas, Dafydd, primary, Nagrath, Sunitha, primary, Morgan, Todd, primary, and Day, Mark L., primary

Published
2023
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47. Supplementary Results from The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Author

Palanisamy, Nallasivam, primary, Yang, Jun, primary, Shepherd, Peter D.A., primary, Li-Ning-Tapia, Elsa M., primary, Labanca, Estefania, primary, Manyam, Ganiraju C., primary, Ravoori, Murali K., primary, Kundra, Vikas, primary, Araujo, John C., primary, Efstathiou, Eleni, primary, Pisters, Louis L., primary, Wan, Xinhai, primary, Wang, Xuemei, primary, Vazquez, Elba S., primary, Aparicio, Ana M., primary, Carskadon, Shannon L., primary, Tomlins, Scott A., primary, Kunju, Lakshmi P., primary, Chinnaiyan, Arul M., primary, Broom, Bradley M., primary, Logothetis, Christopher J., primary, Troncoso, Patricia, primary, and Navone, Nora M., primary

Published
2023
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48. Supplemental Figure Legends from Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay

Author

Wang, Lisha, primary, Harms, Paul W., primary, Palanisamy, Nallasivam, primary, Carskadon, Shannon, primary, Cao, Xuhong, primary, Siddiqui, Javed, primary, Patel, Rajiv M., primary, Zelenka-Wang, Sylvia, primary, Durham, Alison B., primary, Fullen, Douglas R., primary, Harms, Kelly L., primary, Su, Fengyun, primary, Shukla, Sudhanshu, primary, Mehra, Rohit, primary, and Chinnaiyan, Arul M., primary

Published
2023
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49. Supporting Information for CTC clusters in early lung cancer from Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers

Author

Murlidhar, Vasudha, primary, Reddy, Rishindra M., primary, Fouladdel, Shamileh, primary, Zhao, Lili, primary, Ishikawa, Martin K., primary, Grabauskiene, Svetlana, primary, Zhang, Zhuo, primary, Lin, Jules, primary, Chang, Andrew C., primary, Carrott, Philip, primary, Lynch, William R., primary, Orringer, Mark B., primary, Kumar-Sinha, Chandan, primary, Palanisamy, Nallasivam, primary, Beer, David G., primary, Wicha, Max S., primary, Ramnath, Nithya, primary, Azizi, Ebrahim, primary, and Nagrath, Sunitha, primary

Published
2023
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50. Supplementary Figures from Virus-positive Merkel Cell Carcinoma Is an Independent Prognostic Group with Distinct Predictive Biomarkers

Author

Harms, Kelly L., primary, Zhao, Lili, primary, Johnson, Bryan, primary, Wang, Xiaoming, primary, Carskadon, Shannon, primary, Palanisamy, Nallasivam, primary, Rhodes, Daniel R., primary, Mannan, Rahul, primary, Vo, Josh N., primary, Choi, Jae Eun, primary, Chan, May P., primary, Fullen, Douglas R., primary, Patel, Rajiv M., primary, Siddiqui, Javed, primary, Ma, Vincent T., primary, Hrycaj, Steven, primary, McLean, Scott A., primary, Hughes, Tasha M., primary, Bichakjian, Christopher K., primary, Tomlins, Scott A., primary, and Harms, Paul W., primary

Published
2023
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