153,953 results on '"Palma A"'
Search Results
2. Significant Increase in Oxidative Stress Indices in Erythrocyte Membranes of Obese Patients with Metabolically-Associated Fatty Liver Disease
- Author
-
Valeria Tutino, Valentina De Nunzio, Rossella Donghia, Emanuela Aloisio Caruso, Anna Maria Cisternino, Palma Aurelia Iacovazzi, Anna Margherita Mastrosimini, Elizabeth Alicia Fernandez, Vito Giannuzzi, and Maria Notarnicola
- Subjects
MAFLD ,peroxidation index ,fatty acid profile ,erythrocyte membranes ,Medicine - Abstract
Metabolic dysfunction-associated hepatic steatosis (MAFLD) indicates the metabolic risk associated with hepatic steatosis, overweight and obesity, and clinical evidence of metabolic dysregulation. Since MAFLD is one of the diseases that show a high frequency of alterations in the lipid content of cell membranes, the aim of this study was to evaluate the indices of oxidative damage of erythrocyte membranes in overweight and obese MAFLD subjects. The study was conducted on serum samples and red blood cell membranes of overweight and obese MAFLD subjects. For each patient, biochemical measurements and lipidomic analyses of erythrocytes membranes were performed. Significant differences in fatty acid profiles of RBC membranes were found between overweight and obese patients. In particular, the Peroxidation Index (PI) was higher in the erythrocyte membranes of obese subjects than in overweight subjects. The same behavior was observed for Unsaturation Index (UI) and Free Radical Stress Index (Free RSI), supporting the fact that the systemic increase in oxidative stress was associated with obesity. The study shows that there is a different susceptibility to erythrocyte membrane peroxidation for overweight and obese subjects, and the increased values of oxidative stress indices observed in the erythrocyte membranes of obese patients with MAFLD may be a possible indicator of pro-oxidative events occurring in obesity-related diseases.
- Published
- 2024
- Full Text
- View/download PDF
3. Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
- Author
-
Raman, Gayathri, Ronchini, Samuele, Delaunay, James, Tohuvavohu, Aaron, Kennea, Jamie A., Parsotan, Tyler, Ambrosi, Elena, Bernardini, Maria Grazia, Campana, Sergio, Cusumano, Giancarlo, D'Ai, Antonino, D'Avanzo, Paolo, D'Elia, Valerio, De Pasquale, Massimiliano, Dichiara, Simone, Evans, Phil, Hartmann, Dieter, Kuin, Paul, Melandri, Andrea, O'Brien, Paul, Osborne, Julian P., Page, Kim, Palmer, David M., Sbarufatti, Boris, Tagliaferri, Gianpiero, Troja, Eleonora, Abac, A. G., Abbott, R., Abe, H., Abouelfettouh, I., Acernese, F., Ackley, K., Adamcewicz, C., Adhicary, S., Adhikari, N., Adhikari, R. X., Adkins, V. K., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Aguiar, O. D., Aguilar, I., Aiello, L., Ain, A., Akutsu, T., Albanesi, S., Alfaidi, R. A., Al-Jodah, A., Alléné, C., Allocca, A., Al-Shammari, S., Altin, P. A., Alvarez-Lopez, S., Amato, A., Amez-Droz, L., Amorosi, A., Amra, C., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Andia, M., Ando, M., Andrade, T., Andres, N., Andrés-Carcasona, M., Andrić, T., Anglin, J., Ansoldi, S., Antelis, J. M., Antier, S., Aoumi, M., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Aritomi, N., Armato, F., Arnaud, N., Arogeti, M., Aronson, S. M., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Aubin, F., AultONeal, K., Avallone, G., Babak, S., Badaracco, F., Badger, C., Bae, S., Bagnasco, S., Bagui, E., Bai, Y., Baier, J. G., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Banagiri, S., Banerjee, B., Bankar, D., Baral, P., Barayoga, J. C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Barthelmy, S. D., Barton, M. A., Bartos, I., Basak, S., Basalaev, A., Bassiri, R., Basti, A., Bawaj, M., Baxi, P., Bayley, J. C., Baylor, A. C., Bazzan, M., Bécsy, B., Bedakihale, V. M., Beirnaert, F., Bejger, M., Belardinelli, D., Bell, A. S., Benedetto, V., Beniwal, D., Benoit, W., Bentley, J. D., Yaala, M. Ben, Bera, S., Berbel, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Beroiz, M., Berry, C. P. L., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Bevins, N., Bhandare, R., Bhardwaj, U., Bhatt, R., Bhattacharjee, D., Bhaumik, S., Bhowmick, S., Bianchi, A., Bilenko, I. A., Billingsley, G., Binetti, A., Bini, S., Birnholtz, O., Biscoveanu, S., Bisht, A., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blair, C. D., Blair, D. G., Bobba, F., Bode, N., Bogaert, G., Boileau, G., Boldrini, M., Bolingbroke, G. N., Bolliand, A., Bonavena, L. D., Bondarescu, R., Bondu, F., Bonilla, E., Bonilla, M. S., Bonino, A., Bonnand, R., Booker, P., Borchers, A., Boschi, V., Bose, S., Bossilkov, V., Boudart, V., Boumerdassi, A., Bozzi, A., Bradaschia, C., Brady, P. R., Braglia, M., Branch, A., Branchesi, M., Breschi, M., Briant, T., Brillet, A., Brinkmann, M., Brockill, P., Brockmueller, E., Brooks, A. F., Brown, D. D., Brozzetti, M. L., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Bucci, F., Buchanan, J., Bulashenko, O., Bulik, T., Bulten, H. J., Buonanno, A., Burtnyk, K., Buscicchio, R., Buskulic, D., Buy, C., Byer, R. L., Davies, G. S. Cabourn, Cabras, G., Cabrita, R., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callaghan, J. D., Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Santoro, G. Caneva, Cannavacciuolo, M., Cannon, K. C., Cao, H., Cao, Z., Capistran, L. A., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlassara, M., Carlin, J. B., Carpinelli, M., Carrillo, G., Carter, J. J., Carullo, G., Diaz, J. Casanueva, Casentini, C., Castaldi, G., Castro-Lucas, S. Y., Caudill, S., Cavaglià, M., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, W., Chakraborty, P., Subrahmanya, S. Chalathadka, Chan, C., Chan, J. C. L., Chan, K. H. M., Chan, M., Chan, W. L., Chandra, K., Chang, R. -J., Chanial, P., Chao, S., Chapman-Bird, C., Charlton, E. L., Charlton, P., Chassande-Mottin, E., Chatterjee, C., Chatterjee, Debarati, Chatterjee, Deep, Chaturvedi, M., Chaty, S., Chen, A., Chen, A. H. -Y., Chen, D., Chen, H., Chen, H. Y., Chen, K. H., Chen, X., Chen, Yi-Ru, Chen, Yanbei, Chen, Yitian, Cheng, H. P., Chessa, P., Cheung, H. T., Chia, H. Y., Chiadini, F., Chiang, C., Chiarini, G., Chiba, A., Chiba, R., Chierici, R., Chincarini, A., Chiofalo, M. L., Chiummo, A., Chou, C., Choudhary, S., Christensen, N., Chua, S. S. Y., Chung, K. W., Ciani, G., Ciecielag, P., Cieślar, M., Cifaldi, M., Ciobanu, A. A., Ciolfi, R., Clara, F., Clark, J. A., Clarke, T. A., Clearwater, P., Clesse, S., Cleva, F., Coccia, E., Codazzo, E., Cohadon, P. -F., Colleoni, M., Collette, C. G., Collins, J., Colloms, S., Colombo, A., Colpi, M., Compton, C. M., Conti, L., Cooper, S. J., Corbitt, T. R., Cordero-Carrión, I., Corezzi, S., Cornish, N. J., Corsi, A., Cortese, S., Costa, C. A., Cottingham, R., Coughlin, M. W., Couineaux, A., Coulon, J. -P., Countryman, S. T., Coupechoux, J. -F., Cousins, B., Couvares, P., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Craig, K., Creed, R., Creighton, J. D. E., Creighton, T. D., Cremonese, P., Criswell, A. W., Crockett-Gray, J. C. G., Croquette, M., Crouch, R., Crowder, S. G., Cudell, J. R., Cullen, T. J., Cumming, A., Cuoco, E., Cusinato, M., Dabadie, P., Canton, T. Dal, Dall'Osso, S., Dálya, G., D'Angelo, B., Danilishin, S., D'Antonio, S., Danzmann, K., Darroch, K. E., Dartez, L. P., Dasgupta, A., Datta, S., Dattilo, V., Daumas, A., Davari, N., Dave, I., Davenport, A., Davier, M., Davies, T. F., Davis, D., Davis, L., Davis, M. C., Daw, E. J., Dax, M., De Bolle, J., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., Del Favero, V., De Lillo, F., Dell'Aquila, D., Del Pozzo, W., De Marco, F., De Matteis, F., D'Emilio, V., Demos, N., Dent, T., Depasse, A., DePergola, N., De Pietri, R., De Rosa, R., De Rossi, C., De Simone, R., Dhani, A., Dhurandhar, S., Diab, R., Díaz, M. C., Di Cesare, M., Dideron, G., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giovanni, F., Di Giovanni, M., Di Girolamo, T., Diksha, D., Di Michele, A., Ding, J., Di Pace, S., Di Palma, I., Di Renzo, F., Divyajyoti, Dmitriev, A., Doctor, Z., Dohmen, E., Doleva, P. P., Donahue, L., D'Onofrio, L., Donovan, F., Dooley, K. L., Dooney, T., Doravari, S., Dorosh, O., Drago, M., Driggers, J. C., Drori, Y., Ducoin, J. -G., Dunn, L., Dupletsa, U., D'Urso, D., Duval, H., Duverne, P. -A., Dwyer, S. E., Eassa, C., Ebersold, M., Eckhardt, T., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eichholz, J., Einsle, H., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Emma, M., Engelby, E., Engl, A. J., Errico, L., Essick, R. C., Estellés, H., Estevez, D., Etzel, T., Evans, M., Evstafyeva, T., Ewing, B. E., Ezquiaga, J. M., Fabrizi, F., Faedi, F., Fafone, V., Fairhurst, S., Fan, P. C., Farah, A. M., Farr, B., Farr, W. M., Favaro, G., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Fenyvesi, E., Ferguson, D. L., Ferrante, I., Ferreira, T. A., Fidecaro, F., Fiori, A., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Fleischer, S. M., Fleming, L. S., Floden, E., Foley, E. M., Fong, H., Font, J. A., Fornal, B., Forsyth, P. W. F., Franceschetti, K., Franchini, N., Frasca, S., Frasconi, F., Mascioli, A. Frattale, Frei, Z., Freise, A., Freitas, O., Frey, R., Frischhertz, W., Fritschel, P., Frolov, V. V., Fronzé, G. G., Fuentes-Garcia, M., Fujii, S., Fukunaga, I., Fulda, P., Fyffe, M., Gabella, W. E., Gadre, B., Gair, J. R., Galaudage, S., Gallardo, S., Gallego, B., Gamba, R., Gamboa, A., Ganapathy, D., Ganguly, A., Gaonkar, S. G., Garaventa, B., Garcia-Bellido, J., García-Núñez, C., García-Quirós, C., Gardner, J. W., Gardner, K. A., Gargiulo, J., Garron, A., Garufi, F., Gasbarra, C., Gateley, B., Gayathri, V., Gemme, G., Gennai, A., George, J., George, R., Gerberding, O., Gergely, L., Ghadiri, N., Ghosh, Archisman, Ghosh, Shaon, Ghosh, Shrobana, Ghosh, Suprovo, Ghosh, Tathagata, Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gibson, D. T., Gier, C., Giri, P., Gissi, F., Gkaitatzis, S., Glanzer, J., Gleckl, A. E., Glotin, F., Godfrey, J., Godwin, P., Goebbels, N. L., Goetz, E., Golomb, J., Lopez, S. Gomez, Goncharov, B., González, G., Goodarzi, P., Goodwin-Jones, A. W., Gosselin, M., Göttel, A. S., Gouaty, R., Gould, D. W., Goyal, S., Grace, B., Grado, A., Graham, V., Granados, A. E., Granata, M., Granata, V., Argianas, L. Granda, Gras, S., Grassia, P., Gray, C., Gray, R., Greco, G., Green, A. C., Green, S. M., Green, S. R., Gretarsson, A. M., Gretarsson, E. M., Griffith, D., Griffiths, W. L., Griggs, H. L., Grignani, G., Grimaldi, A., Grimaud, C., Grote, H., Gruson, A. S., Guerra, D., Guetta, D., Guidi, G. M., Guimaraes, A. R., Gulati, H. K., Gulminelli, F., Gunny, A. M., Guo, H., Guo, W., Guo, Y., Gupta, Anchal, Gupta, Anuradha, Gupta, Ish, Gupta, N. C., Gupta, P., Gupta, S. K., Gupta, T., Gupte, N., Gurav, R., Gurs, J., Gutierrez, N., Guzman, F., Haba, D., Haberland, M., Haegel, L., Hain, G., Haino, S., Hall, E. D., Hamilton, E. Z., Hammond, G., Han, W. -B., Haney, M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O. A., Hanselman, A. G., Hansen, H., Hanson, J., Harada, R., Harder, T., Haris, K., Harmark, T., Harms, J., Harry, G. M., Harry, I. W., Haskell, B., Haster, C. -J., Hathaway, J. S., Haughian, K., Hayakawa, H., Hayama, K., Healy, J., Heffernan, A., Heidmann, A., Heintze, M. C., Heinze, J., Heinzel, J., Heitmann, H., Hellman, F., Hello, P., Helmling-Cornell, A. F., Hemming, G., Hendry, M., Heng, I. S., Hennes, E., Hennig, J. -S., Hennig, M., Henshaw, C., Hernandez, A., Hertog, T., Heurs, M., Hewitt, A. L., Higginbotham, S., Hild, S., Hill, P., Hill, S., Himemoto, Y., Hines, A. S., Hirata, N., Hirose, C., Ho, J., Hoang, S., Hochheim, S., Hofman, D., Holland, N. A., Holley-Bockelmann, K., Hollows, I. J., Holmes, Z. J., Holz, D. E., Hong, C., Hornung, J., Hoshino, S., Hough, J., Hourihane, S., Howell, E. J., Hoy, C. G., Hoyland, D., Hrishikesh, C. A., Hsieh, H. -F., Hsiung, C., Hsu, H. C., Hsu, S. -C., Hsu, W. -F., Hu, P., Hu, Q., Huang, H. Y., Huang, Y. -J., Huang, Y., Huang, Y. T., Huddart, A. D., Hughey, B., Hui, D. C. Y., Hui, V., Hur, R., Husa, S., Huxford, R., Huynh-Dinh, T., Iakovlev, A., Iandolo, G. A., Iess, A., Inayoshi, K., Inoue, Y., Iorio, G., Irwin, J., Isi, M., Ismail, M. A., Itoh, Y., Iwaya, M., Iyer, B. R., JaberianHamedan, V., Jacquet, P. -E., Jadhav, S. J., Jadhav, S. P., Jain, T., James, A. L., James, P. A., Jamshidi, R., Jan, A. Z., Jani, K., Janiurek, L., Janquart, J., Janssens, K., Janthalur, N. N., Jaraba, S., Jaranowski, P., Jasal, P., Jaume, R., Javed, W., Jennings, A., Jia, W., Jiang, J., Jin, H. -B., Johansmeyer, K., Johns, G. R., Johnson, N. A., Johnston, R., Johny, N., Jones, D. H., Jones, D. I., Jones, R., Jose, S., Joshi, P., Ju, L., Jung, K., Junker, J., Juste, V., Kajita, T., Kalaghatgi, C., Kalogera, V., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kapadia, S. J., Kapasi, D. P., Karat, S., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Kato, J., Kato, T., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaur, T., Kaushik, R., Kawabe, K., Keitel, D., Kelley-Derzon, J., Kennington, J., Kesharwani, R., Key, J. S., Khadka, S., Khalili, F. Y., Khan, F., Khan, I., Khanam, T., Khazanov, E. A., Khursheed, M., Kiendrebeogo, W., Kijbunchoo, N., Kim, C., Kim, J. C., Kim, K., Kim, M. H., Kim, S., Kim, W. S., Kim, Y. -M., Kimball, C., Kimura, N., Kinley-Hanlon, M., Kinnear, M., Kissel, J. S., Kiyota, T., Klimenko, S., Klinger, T., Knee, A. M., Knust, N., Koch, P., Koehlenbeck, S. M., Koekoek, G., Kohri, K., Kokeyama, K., Koley, S., Kolitsidou, P., Kolstein, M., Komori, K., Kong, A. K. H., Kontos, A., Korobko, M., Kossak, R. V., Kou, X., Koushik, A., Kouvatsos, N., Kovalam, M., Koyama, N., Kozak, D. B., Kranzhoff, S. L., Kringel, V., Krishnendu, N. V., Królak, A., Kuehn, G., Kuijer, P., Kulkarni, S., Ramamohan, A. Kulur, Kumar, A., Kumar, Praveen, Kumar, Prayush, Kumar, Rahul, Kumar, Rakesh, Kume, J., Kuns, K., Kuroyanagi, S., Kuwahara, S., Kwak, K., Kwan, K., Lacaille, G., Lagabbe, P., Laghi, D., Lai, S., Laity, A. H., Lakkis, M. H., Lalande, E., Lalleman, M., Landry, M., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., La Rana, A., La Rosa, I., Lartaux-Vollard, A., Lasky, P. D., Lawrence, J., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., LeBohec, S., Lecoeuche, Y. K., Lee, H. M., Lee, H. W., Lee, K., Lee, R. -K., Lee, R., Lee, S., Lee, Y., Legred, I. N., Lehmann, J., Lehner, L., Lemaître, A., Lenti, M., Leonardi, M., Leonova, E., Lequime, M., Leroy, N., Lesovsky, M., Letendre, N., Lethuillier, M., Levesque, C., Levin, Y., Leyde, K., Li, A. K. Y., Li, K. L., Li, T. G. F., Li, X., Lin, Chien-Yu, Lin, Chun-Yu, Lin, E. T., Lin, F., Lin, H., Lin, L. C. -C., Linde, F., Linker, S. D., Littenberg, T. B., Liu, A., Liu, G. C., Liu, Jian, Llamas, F., Llobera-Querol, J., Lo, R. K. L., Locquet, J. -P., London, L., Longo, A., Lopez, D., Portilla, M. Lopez, Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lott IV, T. P., Lough, J. D., Loughlin, H. A., Lousto, C. O., Lowry, M. J., Lück, H., Lumaca, D., Lundgren, A. P., Lussier, A. W., Ma, L. -T., Ma, S., Ma'arif, M., Macas, R., MacInnis, M., Maciy, R. R., Macleod, D. M., MacMillan, I. A. O., Macquet, A., Macri, D., Maeda, K., Maenaut, S., Hernandez, I. Magaña, Magare, S. S., Magazzù, C., Magee, R. M., Maggio, E., Maggiore, R., Magnozzi, M., Mahesh, M., Mahesh, S., Maini, M., Majhi, S., Majorana, E., Makarem, C. N., Malaquias-Reis, J. A., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mannix, B., Mansell, G. L., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Pina, D. Marín, Marion, F., Márka, S., Márka, Z., Markakis, C., Markosyan, A. S., Markowitz, A., Maros, E., Marquina, A., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, B. B., Martinez, M., Martinez, V., Martini, A., Martinovic, K., Martins, J. C., Martynov, D. V., Marx, E. J., Massaro, L., Masserot, A., Masso-Reid, M., Mastrodicasa, M., Mastrogiovanni, S., Mateu-Lucena, M., Matiushechkina, M., Matsuyama, M., Mavalvala, N., Maxwell, N., McCarrol, G., McCarthy, R., McClelland, D. E., McCormick, S., McCuller, L., McGhee, G. I., McGowan, K. B. M., Mchedlidze, M., McIsaac, C., McIver, J., McKinney, K., McLeod, A., McRae, T., McWilliams, S. T., Meacher, D., Mehta, A. K., Meijer, Q., Melatos, A., Mellaerts, S., Menendez-Vazquez, A., Menoni, C. S., Mercer, R. A., Mereni, L., Merfeld, K., Merilh, E. L., Mérou, J. R., Merritt, J. D., Merzougui, M., Messenger, C., Messick, C., Meyer-Conde, M., Meylahn, F., Mhaske, A., Miani, A., Miao, H., Michaloliakos, I., Michel, C., Michimura, Y., Middleton, H., Miller, A. L., Miller, S., Millhouse, M., Milotti, E., Minenkov, Y., Mio, N., Mir, Ll. M., Mirasola, L., Miravet-Tenés, M., Miritescu, C. -A., Mishra, A. K., Mishra, A., Mishra, C., Mishra, T., Mitchell, A. L., Mitchell, J. G., Mitra, S., Mitrofanov, V. P., Mitselmakher, G., Mittleman, R., Miyakawa, O., Miyamoto, S., Miyoki, S., Mo, G., Mobilia, L., Modafferi, L. M., Mohapatra, S. R. P., Mohite, S. R., Molina-Ruiz, M., Mondal, C., Mondin, M., Montani, M., Moore, C. J., Morales, M., Moraru, D., Morawski, F., More, A., More, S., Moreno, C., Moreno, G., Morisaki, S., Moriwaki, Y., Morras, G., Moscatello, A., Mourier, P., Mours, B., Mow-Lowry, C. M., Mozzon, S., Muciaccia, F., Mukherjee, D., Mukherjee, Samanwaya, Mukherjee, Soma, Mukherjee, Subroto, Mukherjee, Suvodip, Mukund, N., Mullavey, A., Munch, J., Mungioli, C. L., Munn, M., Oberg, W. R. Munn, Murakoshi, M., Murray, P. G., Muusse, S., Nadji, S. L., Nagar, A., Nagarajan, N., Nagler, K. N., Nakamura, K., Nakano, H., Nakano, M., Nandi, D., Napolano, V., Narayan, P., Nardecchia, I., Narola, H., Naticchioni, L., Nayak, R. K., Neil, B. F., Neilson, J., Nelson, A., Nelson, T. J. N., Nery, M., Neunzert, A., Ng, S., Nguyen, C., Nguyen, P., Quynh, L. Nguyen, Nichols, S. A., Nielsen, A. B., Nieradka, G., Niko, A., Nishino, Y., Nishizawa, A., Nissanke, S., Nitoglia, E., Niu, W., Nocera, F., Norman, M., North, C., Novak, J., Siles, J. F. Nuño, Nurbek, G., Nuttall, L. K., Obayashi, K., Oberling, J., O'Dell, J., Oertel, M., Offermans, A., Oganesyan, G., Oh, J. J., Oh, K., Oh, S. H., O'Hanlon, T., Ohashi, M., Ohkawa, M., Ohme, F., Ohta, H., Oliveira, A. S., Oliveri, R., Oloworaran, V., O'Neal, B., Oohara, K., O'Reilly, B., Ormsby, N. D., Orselli, M., O'Shaughnessy, R., Oshima, Y., Oshino, S., Ossokine, S., Osthelder, C., Ottaway, D. J., Ouzriat, A., Overmier, H., Owen, B. J., Pace, A. E., Pagano, R., Page, M. A., Pai, A., Pai, S. A., Pal, A., Pal, S., Palaia, M. A., Palashov, O., Pálfi, M., Palma, P. P., Palomba, C., Pan, K. C., Panda, P. K., Panebianco, L., Pang, P. T. H., Pannarale, F., Pant, B. C., Panther, F. H., Panzer, C. D., Paoletti, F., Paoli, A., Paolone, A., Papalexakis, E. E., Papalini, L., Papigkiotis, G., Parisi, A., Park, J., Parker, W., Pascale, G., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passuello, D., Patane, O., Patel, M., Pathak, D., Pathak, M., Patra, A., Patricelli, B., Patron, A. S., Paul, S., Payne, E., Pearce, T., Pedraza, M., Pegna, R., Pele, A., Arellano, F. E. Peña, Penn, S., Penuliar, M. D., Perego, A., Pereira, A., Perez, J. J., Périgois, C., Perkins, C. C., Perna, G., Perreca, A., Perret, J., Perriès, S., Perry, J. W., Pesios, D., Petrillo, C., Pfeiffer, H. P., Pham, H., Pham, K. A., Phukon, K. S., Phurailatpam, H., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierini, L., Pierra, G., Pierro, V., Pietrzak, M., Pillas, M., Pilo, F., Pinard, L., Pineda-Bosque, C., Pinto, I. M., Pinto, M., Piotrzkowski, B. J., Pirello, M., Pitkin, M. D., Placidi, A., Placidi, E., Planas, M. L., Plastino, W., Poggiani, R., Polini, E., Pompili, L., Poon, J., Porcelli, E., Portell, J., Porter, E. K., Posnansky, C., Poulton, R., Powell, J., Pracchia, M., Pradhan, B. K., Pradier, T., Prajapati, A. K., Prasai, K., Prasanna, R., Prasia, P., Pratten, G., Principe, M., Prodi, G. A., Prokhorov, L., Prosposito, P., Prudenzi, L., Puecher, A., Pullin, J., Punturo, M., Puosi, F., Puppo, P., Pürrer, M., Qi, H., Qin, J., Quéméner, G., Quetschke, V., Quigley, C., Quinonez, P. J., Quitzow-James, R., Raab, F. J., Raaijmakers, G., Radulesco, N., Raffai, P., Rail, S. X., Raja, S., Rajan, C., Rajbhandari, B., Ramirez, D. S., Ramirez, K. E., Vidal, F. A. Ramis, Ramos-Buades, A., Rana, D., Randel, E., Ranjan, S., Rapagnani, P., Ratto, B., Rawat, S., Ray, A., Raymond, V., Razzano, M., Read, J., Payo, M. Recaman, Regimbau, T., Rei, L., Reid, S., Reid, S. W., Reitze, D. H., Relton, P., Renzini, A., Rettegno, P., Revenu, B., Reza, A., Rezac, M., Rezaei, A. S., Ricci, F., Ricci, M., Richards, D., Richardson, C. J., Richardson, J. W., Rijal, A., Riles, K., Riley, H. K., Rinaldi, S., Rittmeyer, J., Robertson, C., Robinet, F., Robinson, M., Rocchi, A., Rolland, L., Rollins, J. G., Romanelli, M., Romano, A. E., Romano, R., Romero, A., Romero-Shaw, I. M., Romie, J. H., Roocke, T. J., Rosa, L., Rosauer, T. J., Rose, C. A., Rosińska, D., Ross, M. P., Rossello, M., Rowan, S., Roy, S. K., Roy, S., Rozza, D., Ruggi, P., Morales, E. Ruiz, Ruiz-Rocha, K., Sachdev, S., Sadecki, T., Sadiq, J., Saffarieh, P., Sah, M. R., Saha, S. S., Sainrat, T., Menon, S. Sajith, Sakai, K., Sakellariadou, M., Sako, T., Sakon, S., Salafia, O. S., Salces-Carcoba, F., Salconi, L., Saleem, M., Salemi, F., Sallé, M., Salvador, S., Sanchez, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sänger, E. M., Saravanan, T. R., Sarin, N., Sasli, A., Sassi, P., Sassolas, B., Satari, H., Sato, R., Sato, S., Sato, Y., Sauter, O., Savage, R. L., Sawada, T., Sawant, H. L., Sayah, S., Schaetzl, D., Scheel, M., Scheuer, J., Schiworski, M. G., Schmidt, P., Schmidt, S., Schnabel, R., Schneewind, M., Schofield, R. M. S., Schouteden, K., Schuler, H., Schulte, B. W., Schutz, B. F., Schwartz, E., Scott, J., Scott, S. M., Seetharamu, T. C., Seglar-Arroyo, M., Sekiguchi, Y., Sellers, D., Sengupta, A. S., Sentenac, D., Seo, E. G., Seo, J. W., Sequino, V., Sergeev, A., Serra, M., Servignat, G., Setyawati, Y., Shaffer, T., Shah, U. S., Shahriar, M. S., Shaikh, M. A., Shams, B., Shao, L., Sharma, A. K., Sharma, P., Sharma-Chaudhary, S., Shawhan, P., Shcheblanov, N. S., Shen, B., Shikano, Y., Shikauchi, M., Shimode, K., Shinkai, H., Shiota, J., Shoemaker, D. H., Shoemaker, D. M., Short, R. W., ShyamSundar, S., Sider, A., Siegel, H., Sieniawska, M., Sigg, D., Silenzi, L., Simmonds, M., Singer, L. P., Singh, A., Singh, D., Singh, M. K., Singha, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, L., Smith, R. J. E., Smith, W. J., Soldateschi, J., Somala, S. N., Somiya, K., Soni, K., Soni, S., Sordini, V., Sorrentino, F., Sorrentino, N., Soulard, R., Souradeep, T., Southgate, A., Sowell, E., Spagnuolo, V., Spencer, A. P., Spera, M., Spinicelli, P., Srivastava, A. K., Stachurski, F., Steer, D. A., Steinlechner, J., Steinlechner, S., Stergioulas, N., Stevens, P., StPierre, M., Strang, L. C., Stratta, G., Strong, M. D., Strunk, A., Sturani, R., Stuver, A. L., Suchenek, M., Sudhagar, S., Sueltmann, N., Sullivan, A. G., Sullivan, K. D., Sun, L., Sunil, S., Sur, A., Suresh, J., Sutton, P. J., Suzuki, Takamasa, Suzuki, Takanori, Swinkels, B. L., Syx, A., Szczepańczyk, M. J., Szewczyk, P., Tacca, M., Tagoshi, H., Tait, S. C., Takahashi, H., Takahashi, R., Takamori, A., Takatani, K., Takeda, H., Takeda, M., Talbot, C. J., Talbot, C., Tamaki, M., Tamanini, N., Tanabe, D., Tanaka, K., Tanaka, S. J., Tanaka, T., Tanasijczuk, A. J., Tang, D., Tanioka, S., Tanner, D. B., Tao, L., Tapia, R. D., Martín, E. N. Tapia San, Tarafder, R., Taranto, C., Taruya, A., Tasson, J. D., Teloi, M., Tenorio, R., Themann, H., Theodoropoulos, A., Thirugnanasambandam, M. P., Thomas, L. M., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tissino, J., Tiwari, A., Tiwari, Shubhanshu, Tiwari, Srishti, Tiwari, V., Todd, M. R., Toivonen, A. M., Toland, K., Tolley, A. E., Tomaru, T., Tomita, K., Tomura, T., Tong-Yu, C., Toriyama, A., Toropov, N., Torres-Forné, A., Torrie, C. I., Toscani, M., Melo, I. Tosta e, Tournefier, E., Trani, A. A., Trapananti, A., Travasso, F., Traylor, G., Trenado, J., Trevor, M., Tringali, M. C., Tripathee, A., Troiano, L., Trovato, A., Trozzo, L., Trudeau, R. J., Tsang, T. T. L., Tso, R., Tsuchida, S., Tsukada, L., Tsutsui, T., Turbang, K., Turconi, M., Turski, C., Ubach, H., Ubhi, A. S., Uchikata, N., Uchiyama, T., Udall, R. P., Uehara, T., Ueno, K., Unnikrishnan, C. S., Ushiba, T., Utina, A., Vacatello, M., Vahlbruch, H., Vaidya, N., Vajente, G., Vajpeyi, A., Valdes, G., Valencia, J., Valentini, M., Vallejo-Peña, S. A., Vallero, S., Valsan, V., van Bakel, N., van Beuzekom, M., van Dael, M., Brand, J. F. J. van den, Broeck, C. Van Den, Vander-Hyde, D. C., van der Sluys, M., Van de Walle, A., van Dongen, J., Vandra, K., van Haevermaet, H., van Heijningen, J. V., Vanosky, J., van Putten, M. H. P. M., van Ranst, Z., van Remortel, N., Vardaro, M., Vargas, A. F., Varma, V., Vasúth, M., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venikoudis, S., Venneberg, J., Verdier, P., Verkindt, D., Verma, B., Verma, P., Verma, Y., Vermeulen, S. M., Veske, D., Vetrano, F., Veutro, A., Vibhute, A. M., Viceré, A., Vidyant, S., Viets, A. D., Vijaykumar, A., Vilkha, A., Villa-Ortega, V., Vincent, E. T., Vinet, J. -Y., Viret, S., Virtuoso, A., Vitale, S., Vocca, H., Voigt, D., von Reis, E. R. G., von Wrangel, J. S. A., Vyatchanin, S. P., Wade, L. E., Wade, M., Wagner, K. J., Walet, R. C., Walker, M., Wallace, G. S., Wallace, L., Wang, H., Wang, J. Z., Wang, W. H., Wang, Z., Waratkar, G., Ward, R. L., Warner, J., Was, M., Washimi, T., Washington, N. Y., Watarai, D., Wayt, K. E., Weaver, B., Weaving, C. R., Webster, S. A., Weinert, M., Weinstein, A. J., Weiss, R., Weller, C. M., Weller, R. A., Wellmann, F., Wen, L., Weßels, P., Wette, K., Whelan, J. T., White, D. D., Whiting, B. F., Whittle, C., Wildberger, J. B., Wilk, O. S., Wilken, D., Willetts, K., Williams, D., Williams, M. J., Williams, N. S., Willis, J. L., Willke, B., Wils, M., Wipf, C. C., Woan, G., Woehler, J., Wofford, J. K., Wolfe, N. E., Wong, D., Wong, H. T., Wong, H. W. Y., Wong, I. C. F., Wright, J. L., Wright, M., Wu, C., Wu, D. S., Wu, H., Wysocki, D. M., Xiao, L., Xu, V. A., Xu, Y., Yadav, N., Yamamoto, H., Yamamoto, K., Yamamoto, M., Yamamoto, T. S., Yamamoto, T., Yamamura, S., Yamazaki, R., Yan, S., Yan, T., Yang, F. W., Yang, F., Yang, K. Z., Yang, L. -C., Yang, Y., Yarbrough, Z., Yeh, S. -W., Yelikar, A. B., Yeung, S. M. C., Yin, X., Yokoyama, J., Yokozawa, T., Yoo, J., Yu, H., Yuzurihara, H., Zadrożny, A., Zannelli, A. J., Zanolin, M., Zeeshan, M., Zelenova, T., Zendri, J. -P., Zeoli, M., Zerrad, M., Zevin, M., Zhang, A. C., Zhang, J., Zhang, L., Zhang, R., Zhang, T., Zhang, Y., Zhao, C., Zhao, Yue, Zhao, Yuhang, Zheng, Y., Zhong, H., Zhong, S., Zhou, R., Zhu, Z. -H., Zimmerman, A. B., Zucker, M. E., and Zweizig, J.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
We present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10$^{-3}$ Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers., Comment: 50 pages, 10 figures, 4 tables
- Published
- 2024
4. Delay in healthcare seeking for young children with severe pneumonia at Mulago National Referral Hospital, Uganda: A mixed methods cross-sectional study.
- Author
-
Phiona Ekyaruhanga, Rebecca Nantanda, Hellen T Aanyu, John Mukisa, Judith Amutuhaire Ssemasaazi, Mukeere John, Palma Aceng, and Joseph Rujumba
- Subjects
Medicine ,Science - Abstract
BackgroundGlobally, pneumonia is the leading infectious cause of under-five mortality, and this can be reduced by prompt healthcare seeking. Data on factors associated with delays in seeking care for children with pneumonia in Uganda is scarce.ObjectivesThe study aimed to determine the prevalence, factors associated with delay, barriers, and facilitators of prompt healthcare seeking for children under five years of age with severe pneumonia attending Mulago National Referral Hospital (MNRH) Uganda.MethodsA mixed methods cross-sectional study was conducted among 384 caregivers of children with severe pneumonia at MNRH. Quantitative data was collected using interviewer-administered structured questionnaires and qualitative data through focus group discussions with caregivers. Descriptive statistics were used to determine the prevalence of delay in care seeking. Logistic regression analysis was used to determine the factors that were independently associated with delay in seeking healthcare. Content thematic analysis was used to analyze for barriers and facilitators of prompt healthcare seeking.ResultsThe prevalence of delay in seeking healthcare was 53.6% (95% CI: 48.6-58.6). Long distance to a hospital (AOR = 1.94, 95% CI 1.22-3.01, p value = 0.003), first seeking care elsewhere (AOR = 3.33, 95% CI 1.85-6.01, p value = 0.001), and monthly income ≤100,000 UGX (28 USD) (AOR = 2.27,95% CI 1.33-3.86, p value = 0.003) were independently associated with delay in seeking healthcare. Limited knowledge of symptoms, delayed referrals, self-medication, and low level of education were barriers to prompt healthcare seeking while recognition of symptoms of severe illness in the child, support from spouses, and availability of money for transport were key facilitators of early healthcare seeking.ConclusionThis study showed that more than half of the caregivers delayed seeking healthcare for their children with pneumonia symptoms. Caregivers who first sought care elsewhere, lived more than 5 km from the hospital, and earned less than 28 USD per month were more likely to delay seeking healthcare for their children with severe pneumonia. Limited knowledge of symptoms of pneumonia, self-medication, and delayed referral hindered prompt care-seeking. Key facilitators of prompt care-seeking were accessibility to health workers, support from spouses, and recognition of symptoms of severe illness in children. There is a need for programs that educate caregivers about pneumonia symptoms, in children less than five years.
- Published
- 2023
- Full Text
- View/download PDF
5. Regional Inequalities among State Universities in Chile: Perspectives on Centralization and Neoliberal Development
- Author
-
Nicolas Fleet, Arturo Flores, Braulio Montiel, and Álvaro Palma
- Abstract
Drawing on perspectives from top state-regional universities' authorities (known as "rectors") and public statistics on higher education, we discuss the sources of regional inequality in the Chilean university system. While there is scarce research on regional inequality for Chilean higher education, it is a well-recognized concern within global debates. In this study, the testimonies of rectors link perceptions of regional inequality to the historic, political, and managerial dimensions that have determined their institutions' development. As the problem of regional inequality stems from a tradition of political centralization, the neoliberal transformations, imposed since 1981, were singled out by the rectors for institutionalizing patterns of marketization that reinforced "inequalities of origin" for state-regional universities. Since the 2000s, trends of massification, regulation, and student protests reshaped higher education, leading to sectorial reform in 2018. However, competitive disadvantages are seen to continue to hinder the public role of state-regional universities. Institutional development strategies emerged, under the direction of rectors, to compensate for such inequalities, differentiating between winners and losers of neoliberal higher education. This article characterizes the modes of reproduction and overcoming of regional inequalities among state universities under neoliberal policy.
- Published
- 2024
6. Measuring Two Constructs of Afterschool Activity Participation: Breadth and Intensity
- Author
-
Jose R. Palma, Martin Van Boekel, and Ashley S. Hufnagle
- Abstract
The benefits of afterschool activity participation for youth development are well-documented. An interesting question dominating this field is whether there is a threshold at which point participating in too many activities (breadth) and spending too much time in those activities (intensity) is negatively associated with desirable outcomes. Using 9th grade student data (N=115,731) from three administrations of a state-wide school survey, we explore whether students' breadth and intensity of afterschool participation is associated with GPA and perceived family and community support. Findings corroborate prior research in demonstrating the association between breadth and intensity. Importantly, we extend the discussion, with three important observations. First, a linear model is insufficient for modeling these complex associations with outcomes. Second, there is a threshold at which too much participation has a negative impact in these outcomes. Third, variations in activities, time windows and indices have small or no influence in the association with outcomes.
- Published
- 2024
7. Hadronic cross section measurements with the DAMPE space mission using 20GeV-10TeV cosmic-ray protons and $^4$He
- Author
-
Alemanno, F., An, Q., Azzarello, P., Barbato, F. C. T., Bernardini, P., Bi, X. J., Cagnoli, I., Cai, M. S., Casilli, E., Catanzani, E., Chang, J., Chen, D. Y., Chen, J. L., Chen, Z. F., Coppin, P., Cui, M. Y., Cui, T. S., Cui, Y. X., Dai, H. T., De Benedittis, A., De Mitri, I., de Palma, F., Di Giovanni, A., Ding, Q., Dong, T. K., Dong, Z. X., Donvito, G., Droz, D., Duan, J. L., Duan, K. K., Fan, R. R., Fan, Y. Z., Fang, F., Fang, K., Feng, C. Q., Feng, L., Frieden, J. M., Fusco, P., Gao, M., Gargano, F., Gong, K., Gong, Y. Z., Guo, D. Y., Guo, J. H., Han, S. X., Hu, Y. M., Huang, G. S., Huang, X. Y., Huang, Y. Y., Ionica, M., Jiang, L. Y., Jiang, Y. Z., Jiang, W., Kong, J., Kotenko, A., Kyratzis, D., Lei, S. J., Li, W. H., Li, W. L., Li, X., Li, X. Q., Liang, Y. M., Liu, C. M., Liu, H., Liu, J., Liu, S. B., Liu, Y., Loparco, F., Luo, C. N., Ma, M., Ma, P. X., Ma, T., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Niu, X. Y., Pan, X., Parenti, A., Peng, W. X., Peng, X. Y., Perrina, C., Putti-Garcia, E., Qiao, R., Rao, J. N., Ruina, A., Sarkar, R., Savina, P., Serpolla, A., Shangguan, Z., Shen, W. H., Shen, Z. Q., Shen, Z. T., Silveri, L., Song, J. X., Stolpovskiy, M., Su, H., Su, M., Sun, H. R., Sun, Z. Y., Surdo, A., Teng, X. J., Tykhonov, A., Wang, J. Z., Wang, L. G., Wang, S., Wang, S. X., Wang, X. L., Wang, Y., Wang, Y. F., Wang, Y. Z., Wang, Z. M., Wei, D. M., Wei, J. J., Wei, Y. F., Wu, D., Wu, J., Wu, S. S., Wu, X., Xia, Z. Q., Xu, H. T., Xu, J., Xu, Z. H., Xu, Z. L., Xu, E. H., Xu, Z. Z., Xue, G. F., Yang, H. B., Yang, P., Yang, Y. Q., Yao, H. J., Yu, Y. H., Yuan, G. W., Yuan, Q., Yue, C., Zang, J. J., Zhang, S. X., Zhang, W. Z., Zhang, Yan, Zhang, Yi, Zhang, Y. J., Zhang, Y. L., Zhang, Y. P., Zhang, Y. Q., Zhang, Z., Zhang, Z. Y., Zhao, C., Zhao, H. Y., Zhao, X. F., Zhou, C. Y., and Zhu, Y.
- Subjects
High Energy Physics - Experiment - Abstract
Precise direct cosmic-ray (CR) measurements provide an important probe to study the energetic particle sources in our Galaxy, and the interstellar environment through which these particles propagate. Uncertainties on hadronic models, ion-nucleon cross sections in particular, are currently the limiting factor towards obtaining more accurate CR ion flux measurements with calorimetric space-based experiments. We present an energy-dependent measurement of the inelastic cross section of protons and helium-4 nuclei (alpha particles) on a Bi$_4$Ge$_3$O$_{12}$ target, using 88 months of data collected by the DAMPE space mission. The kinetic energy range per nucleon of the measurement points ranges from 18 GeV to 9 TeV for protons, and from 5 GeV/n to 3 TeV/n for helium-4 nuclei. Our results lead to a significant improvement of the CR flux normalisation. In the case of helium-4, these results correspond to the first cross section measurements on a heavy target material at energies above 10 GeV/n., Comment: 17 pages, submitted to PRD
- Published
- 2024
8. Diagnosing overdispersion in longitudinal analyses with grouped nominal polytomous data
- Author
-
Salvador, Maria Letícia, Palma, Gabriel Rodrigues, Moral, Rafael de Andrade, and de Lara, Idemauro Antonio Rodrigues
- Subjects
Statistics - Methodology ,Quantitative Biology - Quantitative Methods - Abstract
Experiments in Agricultural Sciences often involve the analysis of longitudinal nominal polytomous variables, both in individual and grouped structures. Marginal and mixed-effects models are two common approaches. The distributional assumptions induce specific mean-variance relationships, however, in many instances, the observed variability is greater than assumed by the model. This characterizes overdispersion, whose identification is crucial for choosing an appropriate modeling framework to make inferences reliable. We propose an initial exploration of constructing a longitudinal multinomial dispersion index as a descriptive and diagnostic tool. This index is calculated as the ratio between the observed and assumed variances. The performance of this index was evaluated through a simulation study, employing statistical techniques to assess its initial performance in different scenarios. We identified that as the index approaches one, it is more likely that this corresponds to a high degree of overdispersion. Conversely, values closer to zero indicate a low degree of overdispersion. As a case study, we present an application in animal science, in which the behaviour of pigs (grouped in stalls) is evaluated, considering three response categories., Comment: 22 pages
- Published
- 2024
9. Discovery of 118 New Ultracool Dwarf Candidates Using Machine Learning Techniques
- Author
-
Brooks, Hunter, Caselden, Dan, Kirkpatrick, J. Davy, Raghu, Yadukrishna, Elachi, Charles, Grigorian, Jake, Trek, Asa, Washburn, Andrew, Higashimura, Hiro, Meisner, Aaron, Schneider, Adam, Faherty, Jacqueline, Marocco, Federico, Gelino, Christopher, Gagné, Jonathan, Bickle, Thomas, Tang, Shih-yun, Rothermich, Austin, Burgasser, Adam, Kuchner, Marc J., Beaulieu, Paul, Bell, John, Colin, Guillaume, Colombo, Giovanni, Dereveanco, Alexandru, Flores, Deiby, Glebov, Konstantin, Gramaize, Leopold, Hamlet, Les, Hinckley, Ken, Kabatnik, Martin, Kiwy, Frank, Martin, David, Palma, Raul, Pendrill, William, Ruiz, Lizzeth, Sanchez, John, Sainio, Arttu, SchÜmann, JÖrg, Schonau, Manfred, Tanner, Christopher, Andersen, Nikolaj Stevnbak, Stenner, Andrés, Thévenot, Melina, Thakur, Vinod, Voloshin, Nikita, and Wedracki, And Zbigniew
- Subjects
Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present the discovery of 118 new ultracool dwarf candidates, discovered using a new machine learning tool, named \texttt{SMDET}, applied to time series images from the Wide-field Infrared Survey Explorer. We gathered photometric and astrometric data to estimate each candidate's spectral type, distance, and tangential velocity. This sample has a photometrically estimated spectral class distribution of 28 M dwarfs, 64 L dwarfs, and 18 T dwarfs. We also identify a T subdwarf candidate, two extreme T subdwarf candidates, and two candidate young ultracool dwarfs. Five objects did not have enough photometric data for any estimations to be made. To validate our estimated spectral types, spectra were collected for 2 objects, yielding confirmed spectral types of T5 (estimated T5) and T3 (estimated T4). Demonstrating the effectiveness of machine learning tools as a new large-scale discovery technique., Comment: 14 pages, 8 figures, 2 tables, extended table 1, accepted to American Astronomical Journal
- Published
- 2024
10. Verification of Geometric Robustness of Neural Networks via Piecewise Linear Approximation and Lipschitz Optimisation
- Author
-
Batten, Ben, Zheng, Yang, De Palma, Alessandro, Kouvaros, Panagiotis, and Lomuscio, Alessio
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition - Abstract
We address the problem of verifying neural networks against geometric transformations of the input image, including rotation, scaling, shearing, and translation. The proposed method computes provably sound piecewise linear constraints for the pixel values by using sampling and linear approximations in combination with branch-and-bound Lipschitz optimisation. The method obtains provably tighter over-approximations of the perturbation region than the present state-of-the-art. We report results from experiments on a comprehensive set of verification benchmarks on MNIST and CIFAR10. We show that our proposed implementation resolves up to 32% more verification cases than present approaches., Comment: ECAI 2024
- Published
- 2024
11. Technology and Performance Benchmarks of IQM's 20-Qubit Quantum Computer
- Author
-
Abdurakhimov, Leonid, Adam, Janos, Ahmad, Hasnain, Ahonen, Olli, Algaba, Manuel, Alonso, Guillermo, Bergholm, Ville, Beriwal, Rohit, Beuerle, Matthias, Bockstiegel, Clinton, Calzona, Alessio, Chan, Chun Fai, Cucurachi, Daniele, Dahl, Saga, Davletkaliyev, Rakhim, Fedorets, Olexiy, Frieiro, Alejandro Gomez, Gao, Zheming, Guldmyr, Johan, Guthrie, Andrew, Hassel, Juha, Heimonen, Hermanni, Heinsoo, Johannes, Hiltunen, Tuukka, Holland, Keiran, Hotari, Juho, Hsu, Hao, Huhtala, Antti, Hyyppä, Eric, Hämäläinen, Aleksi, Ikonen, Joni, Inel, Sinan, Janzso, David, Jaakkola, Teemu, Jenei, Mate, Jolin, Shan, Juliusson, Kristinn, Jussila, Jaakko, Khalid, Shabeeb, Kim, Seung-Goo, Koistinen, Miikka, Kokkoniemi, Roope, Komlev, Anton, Ockeloen-Korppi, Caspar, Koskinen, Otto, Kotilahti, Janne, Kuisma, Toivo, Kukushkin, Vladimir, Kumpulainen, Kari, Kuronen, Ilari, Kylmälä, Joonas, Lamponen, Niclas, Lamprich, Julia, Landra, Alessandro, Leib, Martin, Li, Tianyi, Liebermann, Per, Lintunen, Aleksi, Liu, Wei, Luus, Jürgen, Marxer, Fabian, de Griend, Arianne Meijer-van, Mitra, Kunal, Moqadam, Jalil Khatibi, Mrożek, Jakub, Mäkynen, Henrikki, Mäntylä, Janne, Naaranoja, Tiina, Nappi, Francesco, Niemi, Janne, Ortega, Lucas, Palma, Mario, Papič, Miha, Partanen, Matti, Penttilä, Jari, Plyushch, Alexander, Qiu, Wei, Rath, Aniket, Repo, Kari, Riipinen, Tomi, Ritvas, Jussi, Romero, Pedro Figueroa, Ruoho, Jarkko, Räbinä, Jukka, Saarinen, Sampo, Sagar, Indrajeet, Sargsyan, Hayk, Sarsby, Matthew, Savola, Niko, Savytskyi, Mykhailo, Selinmaa, Ville, Smirnov, Pavel, Suárez, Marco Marín, Sundström, Linus, Słupińska, Sandra, Takala, Eelis, Takmakov, Ivan, Tarasinski, Brian, Thapa, Manish, Tiainen, Jukka, Tosto, Francesca, Tuorila, Jani, Valenzuela, Carlos, Vasey, David, Vehmaanperä, Edwin, Vepsäläinen, Antti, Vienamo, Aapo, Vesanen, Panu, Välimaa, Alpo, Wesdorp, Jaap, Wurz, Nicola, Wybo, Elisabeth, Yang, Lily, and Yurtalan, Ali
- Subjects
Quantum Physics - Abstract
Quantum computing has tremendous potential to overcome some of the fundamental limitations present in classical information processing. Yet, today's technological limitations in the quality and scaling prevent exploiting its full potential. Quantum computing based on superconducting quantum processing units (QPUs) is among the most promising approaches towards practical quantum advantage. In this article the basic technological approach of IQM Quantum Computers is described covering both the QPU and the rest of the full-stack quantum computer. In particular, the focus is on a 20-qubit quantum computer featuring the Garnet QPU and its architecture, which we will scale up to 150 qubits. We also present QPU and system-level benchmarks, including a median 2-qubit gate fidelity of 99.5% and genuinely entangling all 20 qubits in a Greenberger-Horne-Zeilinger (GHZ) state.
- Published
- 2024
12. Combining supervised and unsupervised learning methods to predict financial market movements
- Author
-
Palma, Gabriel Rodrigues, Skoczeń, Mariusz, and Maguire, Phil
- Subjects
Quantitative Finance - Statistical Finance ,Computer Science - Machine Learning - Abstract
The decisions traders make to buy or sell an asset depend on various analyses, with expertise required to identify patterns that can be exploited for profit. In this paper we identify novel features extracted from emergent and well-established financial markets using linear models and Gaussian Mixture Models (GMM) with the aim of finding profitable opportunities. We used approximately six months of data consisting of minute candles from the Bitcoin, Pepecoin, and Nasdaq markets to derive and compare the proposed novel features with commonly used ones. These features were extracted based on the previous 59 minutes for each market and used to identify predictions for the hour ahead. We explored the performance of various machine learning strategies, such as Random Forests (RF) and K-Nearest Neighbours (KNN) to classify market movements. A naive random approach to selecting trading decisions was used as a benchmark, with outcomes assumed to be equally likely. We used a temporal cross-validation approach using test sets of 40%, 30% and 20% of total hours to evaluate the learning algorithms' performances. Our results showed that filtering the time series facilitates algorithms' generalisation. The GMM filtering approach revealed that the KNN and RF algorithms produced higher average returns than the random algorithm., Comment: 22 pages
- Published
- 2024
13. Measurement of neutrino oscillation parameters with the first six detection units of KM3NeT/ORCA
- Author
-
KM3NeT Collaboration, Aiello, S., Albert, A., Alhebsi, A. R., Alshamsi, M., Garre, S. Alves, Ambrosone, A., Ameli, F., Andre, M., Androutsou, E., Aphecetche, L., Ardid, M., Ardid, S., Atmani, H., Aublin, J., Badaracco, F., Bailly-Salins, L., Bardačová, Z., Baret, B., Bariego-Quintana, A., Becherini, Y., Bendahman, M., Benfenati, F., Benhassi, M., Bennani, M., Benoit, D. M., Berbee, E., Bertin, V., Beyer, C., Biagi, S., Boettcher, M., Bonanno, D., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Bozza, R. M., Brânzaş, H., Bretaudeau, F., Breuhaus, M., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Capone, A., Carenini, F., Carretero, V., Cartraud, T., Castaldi, P., Cecchini, V., Celli, S., Cerisy, L., Chabab, M., Chadolias, M., Chen, A., Cherubini, S., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Condorelli, A., Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., Dallier, R., Darras, Y., De Benedittis, A., De Martino, B., De Wasseige, G., Decoene, V., Del Rosso, I., Di Mauro, L. S., Di Palma, I., Díaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Drakopoulou, E., Drouhin, D., Ducoin, J. -G., Dvornický, R., Eberl, T., Eckerová, E., Eddymaoui, A., van Eeden, T., Eff, M., van Eijk, D., Bojaddaini, I. El, Hedri, S. El, Ellajosyula, V., Enzenhöfer, A., Ferrara, G., Filipović, M. D., Filippini, F., Franciotti, D., Fusco, L. A., Gagliardini, S., Gal, T., Méndez, J. García, Soto, A. Garcia, Oliver, C. Gatius, Geißelbrecht, N., Genton, E., Ghaddari, H., Gialanella, L., Gibson, B. K., Giorgio, E., Goos, I., Goswami, P., Gozzini, S. R., Gracia, R., Guidi, C., Guillon, B., Gutiérrez, M., Haack, C., van Haren, H., Heijboer, A., Hennig, L., Hernández-Rey, J. J., Ibnsalih, W. Idrissi, Illuminati, G., Joly, D., de Jong, M., de Jong, P., Jung, B. J., Kistauri, G., Kopper, C., Kouchner, A., Kovalev, Y. Y., Kueviakoe, V., Kulikovskiy, V., Kvatadze, R., Labalme, M., Lahmann, R., Lamoureux, M., Larosa, G., Lastoria, C., Lazo, A., Stum, S. Le, Lehaut, G., Lemaítre, V., Leonora, E., Lessing, N., Levi, G., Clark, M. Lindsey, Longhitano, F., Magnani, F., Majumdar, J., Malerba, L., Mamedov, F., Mańczak, J., Manfreda, A., Marconi, M., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Mastrodicasa, M., Mastroianni, S., Mauro, J., Miele, G., Migliozzi, P., Migneco, E., Mitsou, M. L., Mollo, C. M., Morales-Gallegos, L., Moretti, G., Moussa, A., Mateo, I. Mozun, Muller, R., Musone, M. R., Musumeci, M., Napoli, P., Navas, S., Nayerhoda, A., Nicolau, C. A., Nkosi, B., Fearraigh, B. Ó, Oliviero, V., Orlando, A., Oukacha, E., Paesani, D., González, J. Palacios, Papalashvili, G., Parisi, V., Gomez, E. J. Pastor, Păun, A. M., Păvălaş, G. E., Pelegris, I., Martínez, S. Peña, Perrin-Terrin, M., Pestel, V., Pestes, R., Piattelli, P., Plavin, A., Poirè, C., Popa, V., Pradier, T., Prado, J., Pulvirenti, S., Quiroz-Rangel, C. A., Rahaman, U., Randazzo, N., Razzaque, S., Rea, I. C., Real, D., Riccobene, G., Robinson, J., Romanov, A., Ros, E., Šaina, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanfilippo, S., Sanguineti, M., Santonocito, D., Sapienza, P., Schnabel, J., Schumann, J., Schutte, H. M., Seneca, J., Sennan, N., Setter, B., Sgura, I., Shanidze, R., Sharma, A., Shitov, Y., Šimkovic, F., Simonelli, A., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Štekl, I., Stellacci, S. M., Taiuti, M., Tayalati, Y., Thiersen, H., Thoudam, S., de la Torre, P., Melo, I. Tosta e, Tragia, E., Trocmé, B., Tsourapis, V., Tudorache, A., Tzamariudaki, E., Ukleja, A., Vacheret, A., Valsecchi, V., Van Elewyck, V., Vannoye, G., Vasileiadis, G., de Sola, F. Vazquez, Veutro, A., Viola, S., Vivolo, D., van Vliet, A., Warnhofer, H., Weissbrod, S., de Wolf, E., Yvon, I., Zarpapis, G., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.
- Subjects
High Energy Physics - Experiment - Abstract
KM3NeT/ORCA is a water Cherenkov neutrino detector under construction and anchored at the bottom of the Mediterranean Sea. The detector is designed to study oscillations of atmospheric neutrinos and determine the neutrino mass ordering. This paper focuses on an initial configuration of ORCA, referred to as ORCA6, which comprises six out of the foreseen 115 detection units of photo-sensors. A high-purity neutrino sample was extracted, corresponding to an exposure of 433 kton-years. The sample of 5828 neutrino candidates is analysed following a binned log-likelihood method in the reconstructed energy and cosine of the zenith angle. The atmospheric oscillation parameters are measured to be $\sin^2\theta_{23}= 0.51^{+0.04}_{-0.05}$, and $ \Delta m^2_{31} = 2.14^{+0.25}_{-0.35}\times 10^{-3}~\mathrm{eV^2} \cup \{-2.25,-1.76\}\times 10^{-3}~\mathrm{eV^2}$ at 68\% CL. The inverted neutrino mass ordering hypothesis is disfavoured with a p-value of 0.25., Comment: 25 pages, 10 figures
- Published
- 2024
14. Large-scale cosmic ray anisotropies with 19 years of data from the Pierre Auger Observatory
- Author
-
The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Ambrosone, A., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Freitas, M., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Ghia, P. L., Giaccari, U., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kubatova, M., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lundquist, J. P., Payeras, A. Machado, Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Sampathkumar, P., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Weitz, M., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Results are presented for the measurement of large-scale anisotropies in the arrival directions of ultra-high-energy cosmic rays detected at the Pierre Auger Observatory during 19 years of operation, prior to AugerPrime, the upgrade of the Observatory. The 3D dipole amplitude and direction are reconstructed above $4\,$EeV in four energy bins. Besides the established dipolar anisotropy in right ascension above $8\,$EeV, the Fourier amplitude of the $8$ to $16\,$EeV energy bin is now also above the $5\sigma$ discovery level. No time variation of the dipole moment above $8\,$EeV is found, setting an upper limit to the rate of change of such variations of $0.3\%$ per year at the $95\%$ confidence level. Additionally, the results for the angular power spectrum are shown, demonstrating no other statistically significant multipoles. The results for the equatorial dipole component down to $0.03\,$EeV are presented, using for the first time a data set obtained with a trigger that has been optimized for lower energies. Finally, model predictions are discussed and compared with observations, based on two source emission scenarios obtained in the combined fit of spectrum and composition above $0.6\,$EeV.
- Published
- 2024
15. Building spectral templates and reconstructing parameters for core collapse supernovae with CASTOR
- Author
-
Simongini, Andrea, Ragosta, Fabio, Piranomonte, Silvia, and Di Palma, Irene
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
The future of time-domain optical astronomy relies on the development of techniques and software capable of handling a rising amount of data and gradually complementing, or replacing if necessary, real observations. Next generation surveys, like the Large Synoptic Survey Telescope (LSST), will open the door to the new era of optical astrophysics, creating, at the same time, a deficiency in spectroscopic data necessary to confirm the nature of each event and to fully recover the parametric space. In this framework, we developed Core collApse Supernovae parameTers estimatOR (CASTOR), a novel software for data analysis. CASTOR combines Gaussian Process and other Machine Learning techniques to build time-series templates of synthetic spectra and to estimate parameters of core collapse supernovae for which only multi-band photometry is available. Techniques to build templates are fully data driven and non-parametric through empirical and robust models, and rely on the direct comparison with a training set of 111 core collapse supernovae from the literature. Furthermore, CASTOR employees the real photometric data and the reconstructed synthetic spectra of an event to estimate parameters that belong to the supernova ejecta, to the stellar progenitor and to the event itself, in a rapid and user-friendly framework. In this work we provide a demonstration of how CASTOR works, studying available data from SN2015ap and comparing our results with those available in literature., Comment: 17 pages, 5 figures. Accepted for publication in MNRAS
- Published
- 2024
- Full Text
- View/download PDF
16. Beta regression mixed model applied to sensory analysis
- Author
-
Alves, João César Reis, Palma, Gabriel Rodrigues, and de Lara, Idemauro Antonio Rodrigues
- Subjects
Quantitative Biology - Quantitative Methods - Abstract
Sensory analysis is an important area that the food industry can use to innovate and improve its products. This study involves a sample of individuals who can be trained or not to assess a product using a hedonic scale or notes, where the experimental design is a balanced incomplete block design. In this context, integrating sensory analysis with effective statistical methods, which consider the nature of the response variables, is essential to answer the aim of the experimental study. Some techniques are available to analyse sensory data, such as response surface models or categorical models. This article proposes using beta regression as an alternative to the proportional odds model, addressing some convergence problems, especially regarding the number of parameters. Moreover, the beta distribution is flexible for heteroscedasticity and asymmetry data. To this end, we conducted simulation studies that showed agreement rates in product selection using both models. Also, we presented a motivational study that was developed to select prebiotic drinks based on cashew nuts added to grape juice. In this application, the beta regression mixed model results corroborated with the selected formulations using the proportional mixed model., Comment: 13 pages
- Published
- 2024
17. Plasmonic Brownian Ratchets for Directed Transport of Analytes
- Author
-
Carmo, Marciano Palma do, Mack, David, Roth, Diane J., Zhao, Miao, Devis, Ancin M., Rodríguez-Fortuño, Francisco J., Maier, Stefan A., Huidobro, Paloma A., and Rakovich, Aliaksandra
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Controlled long-range transport of micro- and nano-scale objects is a key requirement in lab-on-a-chip and microfluidic applications, enabling the efficient capture, concentration, manipulation, and detection of analytes. Traditional methods such as microfluidic pumps and optical trapping face challenges including high power consumption and limited range of action. This study introduces a plasmonic Brownian ratchet designed for the directed transport of dielectric nanometer-sized particles at low optical powers. Through numerical simulations, the ratchet geometry was optimized to enhance electric fields, optical forces, and trapping potentials. Experimentally, the plasmonic ratchet demonstrated the ability to rectify random thermal motion of 40 nm polysterene spheres over extended distances in a specific direction, achieving velocities up to 2.4 $\mu$m/s at excitation powers as low as 0.785 kW/cm^2. This plasmonic ratchet offers a robust and efficient solution for the targeted delivery and concentration of nanoscale analytes on chips, with significant implications for advancing applications in the life sciences., Comment: to be submitted to ACS Nano
- Published
- 2024
18. Topological Woodward-Hoffmann classification for cycloadditions in polycyclic aromatic azomethine ylides
- Author
-
Li, Juan, Mirzanejad, Amir, Dong, Wen-Han, Liu, Kun, Richter, Marcus, Wang, Xiao-Ye, Berger, Reinhard, Du, Shixuan, Auwärter, Willi, Barth, Johannes V., Ma, Ji, Müllen, Klaus, Feng, Xinliang, Sun, Jia-Tao, Muechler, Lukas, and Palma, Carlos-Andres
- Subjects
Physics - Chemical Physics - Abstract
The study of cycloaddition mechanisms is central to the fabrication of extended sp2 carbon nanostructures. Reaction modeling in this context has focused mostly on putative, energetically preferred, exothermic products with limited consideration for symmetry allowed or forbidden mechanistic effects. Here, we introduce a scheme for classifying symmetry-forbidden reaction coordinates in Woodward-Hoffmann correlation diagrams. Topological classifiers grant access to the study of reaction pathways and correlation diagrams in the same footing, for the purpose of elucidating mechanisms and products of polycyclic aromatic azomethine ylide (PAMY) cycloadditions with pentacene-yielding polycyclic aromatic hydrocarbons with an isoindole core in the solid-state and on surfaces as characterized by mass spectrometry and scanning tunneling microscopy, respectively. By means of a tight-binding reaction model and density functional theory (DFT) we find topologically-allowed pathways if a product is endothermic, and topologically-forbidden if a product is exothermic. Our work unveils topological classification as a crucial element for reaction modeling for nanographene engineering, and highlights its fundamental role in the design of cycloadditions in on-surface and solid-state chemical reactions, while underscoring that exothermic pathways can be topologically-forbidden.
- Published
- 2024
19. Thermal spin-crossover and temperature-dependent zero-field splitting in magnetic nanographene chains
- Author
-
Wang, Yan, Paz, Alejandro Pérez, Boström, Emil Viñas, Zhang, Xiaoxi, Li, Juan, Berger, Reinhard, Liu, Kun, Ma, Ji, Huang, Li, Du, Shixuan, Gao, Hong-jun, Müllen, Klaus, Narita, Akimitsu, Feng, Xinliang, Rubio, Angel, and Palma, CA
- Subjects
Physics - Chemical Physics - Abstract
Nanographene-based magnetism at interfaces offers an avenue to designer quantum materials towards novel phases of matter and atomic-scale applications. Key to spintronics applications at the nanoscale is bistable spin-crossover which however remains to be demonstrated in nanographenes. Here we show that antiaromatic 1,4-disubstituted pyrazine-embedded nanographene derivatives, which promote magnetism through oxidation to a non-aromatic radical are prototypical models for the study of carbon-based thermal spin-crossover. Scanning tunneling spectroscopy studies reveal symmetric spin excitation signals which evolve at Tc to a zero-energy peak, and are assigned to the transition of a S = 3/2 high-spin to a S = 1/2 low-spin state by density functional theory. At temperatures below and close to the spin-crossover Tc, the high-spin S= 3/2 excitations evidence pronouncedly different temperature-dependent excitation energies corresponding to a zero-field splitting in the Hubbard-Kanamori Hamiltonian. The discovery of thermal spin crossover and temperature-dependent zero-field splitting in carbon nanomaterials promises to accelerate quantum information, spintronics and thermometry at the atomic scale.
- Published
- 2024
20. The Fourth S-PLUS Data Release: 12-filter photometry covering $\sim3000$ square degrees in the southern hemisphere
- Author
-
Herpich, Fabio R., Almeida-Fernandes, Felipe, Schwarz, Gustavo B. Oliveira, Lima, Erik V. R., Nakazono, Lilianne, Alonso-García, Javier, Fonseca-Faria, Marcos A., Sartori, Marilia J., Bolutavicius, Guilherme F., de Souza, Gabriel Fabiano, Hartmann, Eduardo A., Li, Liana, Espinosa, Luna, Kanaan, Antonio, Schoenell, William, Werle, Ariel, Machado-Pereira, Eduardo, Gutiérrez-Soto, Luis A., Santos-Silva, Thaís, Castelli, Analia V. Smith, Lacerda, Eduardo A. D., Barbosa, Cassio L., Perottoni, Hélio D., Lopes, Carlos E. Ferreira, Valença, Raquel Ruiz, Martho, Pierre Augusto Re, Bom, Clecio R., Bonatto, Charles J., Carvalho, Maiara S., Cernic, Vitor, Fernandes, Roberto Cid, Coelho, Paula, Cortesi, Ariana, Palma, Barbara Cubillos, Doubrawa, Lia, Alberice, Vincenzo Sivero Ferreira, Huaynasi, Fredi Quispe, Perin, Gabriel Jacob, Arancibia, Marcelo Jaque, Krabbe, Angela, Lima-Dias, Ciria, Lomelí-Núñez, Luis, de Oliveira, Raimundo Lopes, Lopes, Amanda R., Figueiredo, André Luiz, Lösch, Elismar, Navarete, Felipe, de Oliveira, Julia Mello, Overzier, Roderik, Placco, Vinicius M., Roig, Fernando V., Rubet, Mariana, Santos, André, Sasse, Victor Hugo, Thaina-Batista, Julia, Torres-Flores, Sergio, Beers, Timothy C., Alvarez-Candal, Alvaro, Akras, Stavros, Panda, Swayamtrupta, Limberg, Guilherme, Castellón, José Luis Nilo, Telles, Eduardo, Lopes, Paulo Afranio, Montaguth, Gissel Dayana Pardo, Silva, Leandro Beraldo e, Humire, Pedro K., Fernandes, Marcelo Borges, Cordeiro, Vinícius, Ribeiro, Tiago, and de Oliveira, Claudia Mendes
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The Southern Photometric Local Universe Survey (S-PLUS) is a project to map $\sim9300$ sq deg of the sky using twelve bands (seven narrow and five broadbands). Observations are performed with the T80-South telescope, a robotic telescope located at the Cerro Tololo Observatory in Chile. The survey footprint consists of several large contiguous areas, including fields at high and low galactic latitudes, and towards the Magellanic Clouds. S-PLUS uses fixed exposure times to reach point source depths of about $21$ mag in the $griz$ and $20$ mag in the $u$ and the narrow filters. This paper describes the S-PLUS Data Release 4 (DR4), which includes calibrated images and derived catalogues for over 3000 sq deg, covering the aforementioned area. The catalogues provide multi-band photometry performed with the tools \texttt{DoPHOT} and \texttt{SExtractor} -- point spread function (\PSF) and aperture photometry, respectively. In addition to the characterization, we also present the scientific potential of the data. We use statistical tools to present and compare the photometry obtained through different methods. Overall we find good agreement between the different methods, with a slight systematic offset of 0.05\,mag between our \PSF and aperture photometry. We show that the astrometry accuracy is equivalent to that obtained in previous S-PLUS data releases, even in very crowded fields where photometric extraction is challenging. The depths of main survey (MS) photometry for a minimum signal-to-noise ratio $S/N = 3$ reach from $\sim19.5$ for the bluer bands to $\sim21.5$ mag on the red. The range of magnitudes over which accurate \PSF photometry is obtained is shallower, reaching $\sim19$ to $\sim20.5$ mag depending on the filter. Based on these photometric data, we provide star-galaxy-quasar classification and photometric redshift for millions of objects., Comment: 26 pages, 17 figures, 14 tables, accepted for A&A
- Published
- 2024
21. Building spin-1/2 antiferromagnetic Heisenberg chains with diaza-nanographenes
- Author
-
Fu, Xiaoshuai, Huang, Li, Liu, Kun, Henriques, João C. G., Gao, Yixuan, Han, Xianghe, Chen, Hui, Wang, Yan, Palma, Carlos-Andres, Cheng, Zhihai, Lin, Xiao, Du, Shixuan, Ma, Ji, Fernández-Rossier, Joaquín, Feng, Xinliang, and Gao, Hong-Jun
- Subjects
Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics ,Physics - Chemical Physics ,Quantum Physics - Abstract
Understanding and engineering the coupling of spins in nanomaterials is of central importance for designing novel devices. Graphene nanostructures with {\pi}-magnetism offer a chemically tunable platform to explore quantum magnetic interactions. However, realizing spin chains bearing controlled odd-even effects with suitable nanographene systems is challenging. Here, we demonstrate the successful on-surface synthesis of spin-1/2 antiferromagnetic Heisenberg chains with parity-dependent magnetization based on antiaromatic diaza-hexa-peri-hexabenzocoronene (diaza-HBC) units. Using distinct synthetic strategies, two types of spin chains with different terminals were synthesized, both exhibiting a robust odd-even effect on the spin coupling along the chain. Combined investigations using scanning tunneling microscopy, non-contact atomic force microscopy, density functional theory calculations, and quantum spin models confirmed the structures of the diaza-HBC chains and revealed their magnetic properties, which has an S = 1/2 spin per unit through electron donation from the diaza-HBC core to the Au(111) substrate. Gapped excitations were observed in even-numbered chains, while enhanced Kondo resonance emerged in odd-numbered units of odd-numbered chains due to the redistribution of the unpaired spin along the chain. Our findings provide an effective strategy to construct nanographene spin chains and unveil the odd-even effect in their magnetic properties, offering potential applications in nanoscale spintronics.
- Published
- 2024
22. Affinity-aware Serverless Function Scheduling
- Author
-
De Palma, Giuseppe, Giallorenzo, Saverio, Mauro, Jacopo, Trentin, Matteo, and Zavattaro, Gianluigi
- Subjects
Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Functions-as-a-Service (FaaS) is a Serverless Cloud paradigm where a platform manages the scheduling (e.g., resource allocation, runtime environments) of stateless functions. Recent developments show the benefits of using domain-specific languages to express per-function policies, e.g., policies can enforce the allocation of functions on nodes that enjoy lower data-access latencies thanks to proximity and connection pooling. Here, we focus on affinity-aware scenarios, i.e., where, for performance and functional requirements, the allocation of a function depends on the presence/absence of other functions on nodes. We first present aAPP, an affinity-aware extension of a declarative, platform-agnostic language for defining custom function scheduling policies. We implement a prototype supporting this scheduling language by extending the popular Apache OpenWhisk FaaS platform and show that using aAPP in affinity-aware scenarios leads to an appreciable reduction in latency without noticeable overhead for scenarios without affinity constraints., Comment: 16, 6 figures, 1 listing. arXiv admin note: substantial text overlap with arXiv:2407.14159
- Published
- 2024
23. On the Complexity of Reachability Properties in Serverless Function Scheduling
- Author
-
De Palma, Giuseppe, Giallorenzo, Saverio, Mauro, Jacopo, Trentin, Matteo, and Zavattaro, Gianluigi
- Subjects
Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Functions-as-a-Service (FaaS) is a Serverless Cloud paradigm where a platform manages the execution scheduling (e.g., resource allocation, runtime environments) of stateless functions. Recent developments demonstrate the benefits of using domain-specific languages to express per-function scheduling policies, e.g., enforcing the allocation of functions on nodes that enjoy low data-access latencies thanks to proximity and connection pooling. We present aAPP, an affinity-aware extension of a platform-agnostic function scheduling language. We formalise its scheduling semantics and then study the complexity of statically checking reachability properties, e.g., useful to verify that trusted and untrusted functions cannot be co-located. Analysing different fragments of aAPP, we show that checking reachability of policies without affinity has linear complexity, while affinity makes the problem PSpace., Comment: 26 pages, 3 figures, 2 listing, appendix
- Published
- 2024
24. Length-Aware Motion Synthesis via Latent Diffusion
- Author
-
Sampieri, Alessio, Palma, Alessio, Spinelli, Indro, and Galasso, Fabio
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
The target duration of a synthesized human motion is a critical attribute that requires modeling control over the motion dynamics and style. Speeding up an action performance is not merely fast-forwarding it. However, state-of-the-art techniques for human behavior synthesis have limited control over the target sequence length. We introduce the problem of generating length-aware 3D human motion sequences from textual descriptors, and we propose a novel model to synthesize motions of variable target lengths, which we dub "Length-Aware Latent Diffusion" (LADiff). LADiff consists of two new modules: 1) a length-aware variational auto-encoder to learn motion representations with length-dependent latent codes; 2) a length-conforming latent diffusion model to generate motions with a richness of details that increases with the required target sequence length. LADiff significantly improves over the state-of-the-art across most of the existing motion synthesis metrics on the two established benchmarks of HumanML3D and KIT-ML., Comment: Accepted at ECCV 2024
- Published
- 2024
25. Generating Multi-Modal and Multi-Attribute Single-Cell Counts with CFGen
- Author
-
Palma, Alessandro, Richter, Till, Zhang, Hanyi, Lubetzki, Manuel, Tong, Alexander, Dittadi, Andrea, and Theis, Fabian
- Subjects
Quantitative Biology - Quantitative Methods ,Computer Science - Machine Learning ,Quantitative Biology - Genomics - Abstract
Generative modeling of single-cell RNA-seq data has shown invaluable potential in community-driven tasks such as trajectory inference, batch effect removal and gene expression generation. However, most recent deep models generating synthetic single cells from noise operate on pre-processed continuous gene expression approximations, ignoring the inherently discrete and over-dispersed nature of single-cell data, which limits downstream applications and hinders the incorporation of robust noise models. Moreover, crucial aspects of deep-learning-based synthetic single-cell generation remain underexplored, such as controllable multi-modal and multi-label generation and its role in the performance enhancement of downstream tasks. This work presents Cell Flow for Generation (CFGen), a flow-based conditional generative model for multi-modal single-cell counts, which explicitly accounts for the discrete nature of the data. Our results suggest improved recovery of crucial biological data characteristics while accounting for novel generative tasks such as conditioning on multiple attributes and boosting rare cell type classification via data augmentation. By showcasing CFGen on a diverse set of biological datasets and settings, we provide evidence of its value to the fields of computational biology and deep generative models., Comment: 28 pages, 12 figures
- Published
- 2024
26. An Adaptive Indoor Localization Approach Using WiFi RSSI Fingerprinting with SLAM-Enabled Robotic Platform and Deep Neural Networks
- Author
-
Azghadi, Seyed Alireza Rahimi, Mih, Atah Nuh, Kawnine, Asfia, Wachowicz, Monica, Palma, Francis, and Cao, Hung
- Subjects
Computer Science - Robotics ,Computer Science - Emerging Technologies ,Computer Science - Networking and Internet Architecture - Abstract
Indoor localization plays a vital role in the era of the IoT and robotics, with WiFi technology being a prominent choice due to its ubiquity. We present a method for creating WiFi fingerprinting datasets to enhance indoor localization systems and address the gap in WiFi fingerprinting dataset creation. We used the Simultaneous Localization And Mapping (SLAM) algorithm and employed a robotic platform to construct precise maps and localize robots in indoor environments. We developed software applications to facilitate data acquisition, fingerprinting dataset collection, and accurate ground truth map building. Subsequently, we aligned the spatial information generated via the SLAM with the WiFi scans to create a comprehensive WiFi fingerprinting dataset. The created dataset was used to train a deep neural network (DNN) for indoor localization, which can prove the usefulness of grid density. We conducted experimental validation within our office environment to demonstrate the proposed method's effectiveness, including a heatmap from the dataset showcasing the spatial distribution of WiFi signal strengths for the testing access points placed within the environment. Notably, our method offers distinct advantages over existing approaches as it eliminates the need for a predefined map of the environment, requires no preparatory steps, lessens human intervention, creates a denser fingerprinting dataset, and reduces the WiFi fingerprinting dataset creation time. Our method achieves 26% more accurate localization than the other methods and can create a six times denser fingerprinting dataset in one-third of the time compared to the traditional method. In summary, using WiFi RSSI Fingerprinting data surveyed by the SLAM-Enabled Robotic Platform, we can adapt our trained DNN model to indoor localization in any dynamic environment and enhance its scalability and applicability in real-world scenarios., Comment: Fingerprinting dataset; Robotic platform; Indoor localization; Signals strength indicator; Location-based services
- Published
- 2024
27. VVVX survey dusts off a new intermediate-age star cluster in the Milky Way disk
- Author
-
Garro, E. R., Minniti, D., Alonso-García, J., Fernández-Trincado, J. G., Gómez, M., Palma, T., Saito, R. K., and Obasi, C.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
Our primary long-term objective is to seek out additional star clusters in the poorly studied regions of the MW. The aim of this pursuit is to finalize the MG's globular and open cluster system census and to gain a comprehensive understanding of both the formation and evolution of these systems and our Galaxy as a whole. We report the discovery of a new star cluster, named Garro~03. We investigated this target using a combination of near-infrared and optical databases. We employed VVVX and 2MASS data in the NIR, and Gaia DR3 and the DECaPS2 datasets in the optical passband. We performed a photometrical analysis in order to derive its main physical parameters. Garro~03 is located at equatorial coordinates RA=14:01:29.3 and Dec=-65:30:57.0. It is not heavily affected by extinction $A_{Ks}=0.25\pm 0.04$ mag. It is located at heliocentric distance of $14.1\pm0.5$ kpc, which places Garro~03 at 10.6 kpc from the Galactic centre and Z=-0.89 kpc below the Galactic plane. We calculated the mean cluster PM of ($\mu_{\alpha}^{\ast},\mu_{\delta}) = (-4.57\pm 0.29,\ -1.36\pm 0.27$) mas yr$^{-1}$. We derived an age=3 Gyr and [Fe/H]~$= -0.5\pm 0.2$ by the isochrone-fitting method. The total luminosity was derived in the $K_s$ and V-bands, finding $M_{Ks} = -6.32\pm 1.10$ mag and $M_V =-4.06$ mag. The core and tidal radii were measured constructing the Garro~03 radial density profile and fitting the King model, obtaining $r_c = 3.07\pm 0.98$ pc and $r_t = 19.36\pm 15.96$ pc. We photometrically confirm the cluster nature for Garro~03, located in the Galactic disk. It is a distant, low-luminosity, metal-rich star cluster of intermediate age. We also searched for possible signatures (streams or bridges) between Garro~03 and Garro~01, but we exclude a possible companionship. We need spectroscopic data to classify it as an old open cluster or a young globular cluster, and to understand its origin., Comment: 10 pages, 8 figures, accepted for publication in A&A Journal
- Published
- 2024
28. The flux of ultra-high-energy cosmic rays along the supergalactic plane measured at the Pierre Auger Observatory
- Author
-
The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fenu, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Johnsen, J. A., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lu, L., Luce, Q., Lundquist, J. P., Payeras, A. Machado, Majercakova, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reininghaus, M., Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. Rodrigues, Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Smau, R., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Ultra-high-energy cosmic rays are known to be mainly of extragalactic origin, and their propagation is limited by energy losses, so their arrival directions are expected to correlate with the large-scale structure of the local Universe. In this work, we investigate the possible presence of intermediate-scale excesses in the flux of the most energetic cosmic rays from the direction of the supergalactic plane region using events with energies above 20 EeV recorded with the surface detector array of the Pierre Auger Observatory up to 31 December 2022, with a total exposure of 135,000 km^2 sr yr. The strongest indication for an excess that we find, with a post-trial significance of 3.1{\sigma}, is in the Centaurus region, as in our previous reports, and it extends down to lower energies than previously studied. We do not find any strong hints of excesses from any other region of the supergalactic plane at the same angular scale. In particular, our results do not confirm the reports by the Telescope Array collaboration of excesses from two regions in the Northern Hemisphere at the edge of the field of view of the Pierre Auger Observatory. With a comparable exposure, our results in those regions are in good agreement with the expectations from an isotropic distribution., Comment: submitted to ApJ
- Published
- 2024
29. Normative brain mapping of 3-dimensional morphometry imaging data using skewed functional data analysis
- Author
-
Palma, Marco, Tavakoli, Shahin, Brettschneider, Julia, Staicu, Ana-Maria, and Nichols, Thomas E.
- Subjects
Statistics - Applications - Abstract
Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral ventricles. More specifically, our voxelwise analysis shows both a mean-variance relationship in these areas and evidence of spatially dependent skewness. We propose a model for 3-dimensional functional data where mean, variance, and skewness functions vary smoothly across brain locations. We model the voxelwise distributions as skew-normal. The smooth effects of age and sex are estimated on a reference population of cognitively normal subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset and mapped across the whole brain. The three parameter functions allow to transform each TBM image (in the reference population as well as in a test set) into a Gaussian process. These subject-specific normative maps are used to derive indices of deviation from a healthy condition to assess the individual risk of pathological degeneration.
- Published
- 2024
30. Bayesian inference of physics-based models of acoustically-forced laminar premixed conical flames
- Author
-
Giannotta, Alessandro, Yoko, Matthew, Cherubini, Stefania, De Palma, Pietro, and Juniper, Matthew P.
- Subjects
Physics - Fluid Dynamics - Abstract
We perform twenty experiments on an acoustically-forced laminar premixed Bunsen flame and assimilate high-speed footage of the natural emission into a physics-based model containing seven parameters. The experimental rig is a ducted Bunsen flame supplied by a mixture of methane and ethylene. A high-speed camera captures the natural emission of the flame, from which we extract the position of the flame front. We use Bayesian inference to combine this experimental data with our prior knowledge of this flame's behaviour. This prior knowledge is expressed through (i) a model of the kinematics of a flame front moving through a model of the perturbed velocity field, and (ii) a priori estimates of the parameters of the above model with quantified uncertainties. We find the most probable a posteriori model parameters using Bayesian parameter inference, and quantify their uncertainties using Laplace's method combined with first-order adjoint methods. This is substantially cheaper than other common Bayesian inference frameworks, such as Markov Chain Monte Carlo. This process results in a quantitatively-accurate physics-based reduced-order model of the acoustically forced Bunsen flame for injection velocities ranging from 1.75 m/s to 2.99 m/s and equivalence ratio values ranging from 1.26 to 1.47, using seven parameters. We use this model to evaluate the heat release rate between experimental snapshots, to extrapolate to different experimental conditions, and to calculate the flame transfer function and its uncertainty for all the flames. Since the proposed model relies on only seven parameters, it can be trained with little data and successfully extrapolates beyond the training dataset. Matlab code is provided so that the reader can apply it to assimilate further flame images into the model.
- Published
- 2024
31. Observation of Gravitational Waves from the Coalescence of a $2.5\text{-}4.5~M_\odot$ Compact Object and a Neutron Star
- Author
-
The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration, Abac, A. G., Abbott, R., Abouelfettouh, I., Acernese, F., Ackley, K., Adhicary, S., Adhikari, N., Adhikari, R. X., Adkins, V. K., Agarwal, D., Agathos, M., Abchouyeh, M. Aghaei, Aguiar, O. D., Aguilar, I., Aiello, L., Ain, A., Ajith, P., Akçay, S., Akutsu, T., Albanesi, S., Alfaidi, R. A., Al-Jodah, A., Alléné, C., Allocca, A., Al-Shammari, S., Altin, P. A., Alvarez-Lopez, S., Amato, A., Amez-Droz, L., Amorosi, A., Amra, C., Ananyeva, A., Anderson, S. B., Anderson, W. G., Andia, M., Ando, M., Andrade, T., Andres, N., Andrés-Carcasona, M., Andrić, T., Anglin, J., Ansoldi, S., Antelis, J. M., Antier, S., Aoumi, M., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Argianas, L., Aritomi, N., Armato, F., Arnaud, N., Arogeti, M., Aronson, S. M., Arun, K. G., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Attadio, F., Aubin, F., AultONeal, K., Avallone, G., Azrad, D., Babak, S., Badaracco, F., Badger, C., Bae, S., Bagnasco, S., Bagui, E., Baier, J. G., Baiotti, L., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Banagiri, S., Banerjee, B., Bankar, D., Baral, P., Barayoga, J. C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartoletti, A. M., Barton, M. A., Bartos, I., Basak, S., Basalaev, A., Bassiri, R., Basti, A., Bates, D. E., Bawaj, M., Baxi, P., Bayley, J. C., Baylor, A. C., Baynard II, P. A., Bazzan, M., Bedakihale, V. M., Beirnaert, F., Bejger, M., Belardinelli, D., Bell, A. S., Benedetto, V., Benoit, W., Bentara, I., Bentley, J. D., Yaala, M. Ben, Bera, S., Berbel, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Beroiz, M., Berry, C. P. L., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Bevins, N., Bhandare, R., Bhardwaj, U., Bhatt, R., Bhattacharjee, D., Bhaumik, S., Bhowmick, S., Bianchi, A., Bilenko, I. A., Billingsley, G., Binetti, A., Bini, S., Birnholtz, O., Biscoveanu, S., Bisht, A., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blagg, L. A., Blair, C. D., Blair, D. G., Bobba, F., Bode, N., Boileau, G., Boldrini, M., Bolingbroke, G. N., Bolliand, A., Bonavena, L. D., Bondarescu, R., Bondu, F., Bonilla, E., Bonilla, M. S., Bonino, A., Bonnand, R., Booker, P., Borchers, A., Boschi, V., Bose, S., Bossilkov, V., Boudart, V., Boudon, A., Bozzi, A., Bradaschia, C., Brady, P. R., Braglia, M., Branch, A., Branchesi, M., Brandt, J., Braun, I., Breschi, M., Briant, T., Brillet, A., Brinkmann, M., Brockill, P., Brockmueller, E., Brooks, A. F., Brown, B. C., Brown, D. D., Brozzetti, M. L., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Bucci, F., Buchanan, J., Bulashenko, O., Bulik, T., Bulten, H. J., Buonanno, A., Burtnyk, K., Buscicchio, R., Buskulic, D., Buy, C., Byer, R. L., Davies, G. S. Cabourn, Cabras, G., Cabrita, R., Cáceres-Barbosa, V., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Santoro, G. Caneva, Cannon, K. C., Cao, H., Capistran, L. A., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlassara, M., Carlin, J. B., Carpinelli, M., Carrillo, G., Carter, J. J., Carullo, G., Diaz, J. Casanueva, Casentini, C., Castro-Lucas, S. Y., Caudill, S., Cavaglià, M., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, W., Chakraborty, P., Subrahmanya, S. Chalathadka, Chan, J. C. L., Chan, M., Chandra, K., Chang, R. -J., Chao, S., Char, P., Charlton, E. L., Charlton, P., Chassande-Mottin, E., Chatterjee, C., Chatterjee, Debarati, Chatterjee, Deep, Chattopadhyay, D., Chaturvedi, M., Chaty, S., Chatziioannou, K., Chen, A., Chen, A. H. -Y., Chen, D., Chen, H., Chen, H. Y., Chen, J., Chen, K. H., Chen, Y., Chen, Yanbei, Chen, Yitian, Cheng, H. P., Chessa, P., Cheung, H. T., Cheung, S. Y., Chiadini, F., Chiarini, G., Chierici, R., Chincarini, A., Chiofalo, M. L., Chiummo, A., Chou, C., Choudhary, S., Christensen, N., Chua, S. S. Y., Chugh, P., Ciani, G., Ciecielag, P., Cieślar, M., Cifaldi, M., Ciolfi, R., Clara, F., Clark, J. A., Clarke, J., Clarke, T. A., Clearwater, P., Clesse, S., Coccia, E., Codazzo, E., Cohadon, P. -F., Colace, S., Colleoni, M., Collette, C. G., Collins, J., Colloms, S., Colombo, A., Colpi, M., Compton, C. M., Connolly, G., Conti, L., Corbitt, T. R., Cordero-Carrión, I., Corezzi, S., Cornish, N. J., Corsi, A., Cortese, S., Costa, C. A., Cottingham, R., Coughlin, M. W., Couineaux, A., Coulon, J. -P., Countryman, S. T., Coupechoux, J. -F., Couvares, P., Coward, D. M., Cowart, M. J., Coyne, R., Craig, K., Creed, R., Creighton, J. D. E., Creighton, T. D., Cremonese, P., Criswell, A. W., Crockett-Gray, J. C. G., Crook, S., Crouch, R., Csizmazia, J., Cudell, J. R., Cullen, T. J., Cumming, A., Cuoco, E., Cusinato, M., Dabadie, P., Canton, T. Dal, Dall'Osso, S., Pra, S. Dal, Dálya, G., D'Angelo, B., Danilishin, S., D'Antonio, S., Danzmann, K., Darroch, K. E., Dartez, L. P., Dasgupta, A., Datta, S., Dattilo, V., Daumas, A., Davari, N., Dave, I., Davenport, A., Davier, M., Davies, T. F., Davis, D., Davis, L., Davis, M. C., Davis, P. J., Dax, M., De Bolle, J., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., De Lillo, F., Dell'Aquila, D., Del Pozzo, W., De Marco, F., De Matteis, F., D'Emilio, V., Demos, N., Dent, T., Depasse, A., DePergola, N., De Pietri, R., De Rosa, R., De Rossi, C., DeSalvo, R., De Simone, R., Dhani, A., Diab, R., Díaz, M. C., Di Cesare, M., Dideron, G., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giovanni, M., Di Girolamo, T., Diksha, D., Di Michele, A., Ding, J., Di Pace, S., Di Palma, I., Di Renzo, F., Divyajyoti, Dmitriev, A., Doctor, Z., Dohmen, E., Doleva, P. P., Dominguez, D., D'Onofrio, L., Donovan, F., Dooley, K. L., Dooney, T., Doravari, S., Dorosh, O., Drago, M., Driggers, J. C., Ducoin, J. -G., Dunn, L., Dupletsa, U., D'Urso, D., Duval, H., Duverne, P. -A., Dwyer, S. E., Eassa, C., Ebersold, M., Eckhardt, T., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eichholz, J., Einsle, H., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Eleveld, R. M., Emma, M., Endo, K., Engl, A. J., Enloe, E., Errico, L., Essick, R. C., Estellés, H., Estevez, D., Etzel, T., Evans, M., Evstafyeva, T., Ewing, B. E., Ezquiaga, J. M., Fabrizi, F., Faedi, F., Fafone, V., Fairhurst, S., Farah, A. M., Farr, B., Farr, W. M., Favaro, G., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Felicetti, R., Fenyvesi, E., Ferguson, D. L., Ferraiuolo, S., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, A., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Fleischer, S. M., Fleming, L. S., Floden, E., Foley, E. M., Fong, H., Font, J. A., Fornal, B., Forsyth, P. W. F., Franceschetti, K., Franchini, N., Frasca, S., Frasconi, F., Mascioli, A. Frattale, Frei, Z., Freise, A., Freitas, O., Frey, R., Frischhertz, W., Fritschel, P., Frolov, V. V., Fronzé, G. G., Fuentes-Garcia, M., Fujii, S., Fujimori, T., Fulda, P., Fyffe, M., Gadre, B., Gair, J. R., Galaudage, S., Galdi, V., Gallagher, H., Gallardo, S., Gallego, B., Gamba, R., Gamboa, A., Ganapathy, D., Ganguly, A., Garaventa, B., García-Bellido, J., Núñez, C. García, García-Quirós, C., Gardner, J. W., Gardner, K. A., Gargiulo, J., Garron, A., Garufi, F., Gasbarra, C., Gateley, B., Gayathri, V., Gemme, G., Gennai, A., Gennari, V., George, J., George, R., Gerberding, O., Gergely, L., Ghonge, S., Ghosh, Archisman, Ghosh, Sayantan, Ghosh, Shaon, Ghosh, Shrobana, Ghosh, Suprovo, Ghosh, Tathagata, Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gibson, D. T., Gier, C., Giri, P., Gissi, F., Gkaitatzis, S., Glanzer, J., Glotin, F., Godfrey, J., Godwin, P., Goebbels, N. L., Goetz, E., Golomb, J., Lopez, S. Gomez, Goncharov, B., Gong, Y., González, G., Goodarzi, P., Goode, S., Goodwin-Jones, A. W., Gosselin, M., Göttel, A. S., Gouaty, R., Gould, D. W., Govorkova, K., Goyal, S., Grace, B., Grado, A., Graham, V., Granados, A. E., Granata, M., Granata, V., Gras, S., Grassia, P., Gray, A., Gray, C., Gray, R., Greco, G., Green, A. C., Green, S. M., Green, S. R., Gretarsson, A. M., Gretarsson, E. M., Griffith, D., Griffiths, W. L., Griggs, H. L., Grignani, G., Grimaldi, A., Grimaud, C., Grote, H., Guerra, D., Guetta, D., Guidi, G. M., Guimaraes, A. R., Gulati, H. K., Gulminelli, F., Gunny, A. M., Guo, H., Guo, W., Guo, Y., Gupta, Anchal, Gupta, Anuradha, Gupta, Ish, Gupta, N. C., Gupta, P., Gupta, S. K., Gupta, T., Gupte, N., Gurs, J., Gutierrez, N., Guzman, F., H, H. -Y., Haba, D., Haberland, M., Haino, S., Hall, E. D., Hamilton, E. Z., Hammond, G., Han, W. -B., Haney, M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O. A., Hanselman, A. G., Hansen, H., Hanson, J., Harada, R., Hardison, A. R., Haris, K., Harmark, T., Harms, J., Harry, G. M., Harry, I. W., Hart, J., Haskell, B., Haster, C. -J., Hathaway, J. S., Haughian, K., Hayakawa, H., Hayama, K., Hayes, R., Heffernan, A., Heidmann, A., Heintze, M. C., Heinze, J., Heinzel, J., Heitmann, H., Hellman, F., Hello, P., Helmling-Cornell, A. F., Hemming, G., Henderson-Sapir, O., Hendry, M., Heng, I. S., Hennes, E., Henshaw, C., Hertog, T., Heurs, M., Hewitt, A. L., Heyns, J., Higginbotham, S., Hild, S., Hill, S., Himemoto, Y., Hirata, N., Hirose, C., Hoang, S., Hochheim, S., Hofman, D., Holland, N. A., Holley-Bockelmann, K., Holmes, Z. J., Holz, D. E., Honet, L., Hong, C., Hornung, J., Hoshino, S., Hough, J., Hourihane, S., Howell, E. J., Hoy, C. G., Hrishikesh, C. A., Hsieh, H. -F., Hsiung, C., Hsu, H. C., Hsu, W. -F., Hu, P., Hu, Q., Huang, H. Y., Huang, Y. -J., Huddart, A. D., Hughey, B., Hui, D. C. Y., Hui, V., Husa, S., Huxford, R., Huynh-Dinh, T., Iampieri, L., Iandolo, G. A., Ianni, M., Iess, A., Imafuku, H., Inayoshi, K., Inoue, Y., Iorio, G., Iqbal, M. H., Irwin, J., Ishikawa, R., Isi, M., Ismail, M. A., Itoh, Y., Iwanaga, H., Iwaya, M., Iyer, B. R., JaberianHamedan, V., Jacquet, C., Jacquet, P. -E., Jadhav, S. J., Jadhav, S. P., Jain, T., James, A. L., James, P. A., Jamshidi, R., Janquart, J., Janssens, K., Janthalur, N. N., Jaraba, S., Jaranowski, P., Jaume, R., Javed, W., Jennings, A., Jia, W., Jiang, J., Kubisz, J., Johanson, C., Johns, G. R., Johnson, N. A., Johnson-McDaniel, N. K., Johnston, M. C., Johnston, R., Johny, N., Jones, D. H., Jones, D. I., Jones, R., Jose, S., Joshi, P., Ju, L., Jung, K., Junker, J., Juste, V., Kajita, T., Kaku, I., Kalaghatgi, C., Kalogera, V., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kapadia, S. J., Kapasi, D. P., Karat, S., Karathanasis, C., Kashyap, R., Kasprzack, M., Kastaun, W., Kato, T., Katsavounidis, E., Katzman, W., Kaushik, R., Kawabe, K., Kawamoto, R., Kazemi, A., Kedia, A., Keitel, D., Kelley-Derzon, J., Kennington, J., Kesharwani, R., Key, J. S., Khadela, R., Khadka, S., Khalili, F. Y., Khan, F., Khan, I., Khanam, T., Khursheed, M., Khusid, N. M., Kiendrebeogo, W., Kijbunchoo, N., Kim, C., Kim, J. C., Kim, K., Kim, M. H., Kim, S., Kim, Y. -M., Kimball, C., Kinley-Hanlon, M., Kinnear, M., Kissel, J. S., Klimenko, S., Knee, A. M., Knust, N., Kobayashi, K., Koch, P., Koehlenbeck, S. M., Koekoek, G., Kohri, K., Kokeyama, K., Koley, S., Kolitsidou, P., Kolstein, M., Komori, K., Kong, A. K. H., Kontos, A., Korobko, M., Kossak, R. V., Kou, X., Koushik, A., Kouvatsos, N., Kovalam, M., Kozak, D. B., Kranzhoff, S. L., Kringel, V., Krishnendu, N. V., Królak, A., Kruska, K., Kuehn, G., Kuijer, P., Kulkarni, S., Ramamohan, A. Kulur, Kumar, A., Kumar, Praveen, Kumar, Prayush, Kumar, Rahul, Kumar, Rakesh, Kume, J., Kuns, K., Kuntimaddi, N., Kuroyanagi, S., Kurth, N. J., Kuwahara, S., Kwak, K., Kwan, K., Kwok, J., Lacaille, G., Lagabbe, P., Laghi, D., Lai, S., Laity, A. H., Lakkis, M. H., Lalande, E., Lalleman, M., Lalremruati, P. C., Landry, M., Landry, P., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., La Rana, A., La Rosa, I., Lartaux-Vollard, A., Lasky, P. D., Lawrence, J., Lawrence, M. N., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Lecoeuche, Y. K., Lee, H. M., Lee, H. W., Lee, K., Lee, R. -K., Lee, R., Lee, S., Lee, Y., Legred, I. N., Lehmann, J., Lehner, L., Jean, M. Le, Lemaître, A., Lenti, M., Leonardi, M., Lequime, M., Leroy, N., Lesovsky, M., Letendre, N., Lethuillier, M., Levin, S. E., Levin, Y., Leyde, K., Li, A. K. Y., Li, K. L., Li, T. G. F., Li, X., Li, Z., Lihos, A., Lin, C-Y., Lin, C. -Y., Lin, E. T., Lin, F., Lin, H., Lin, L. C. -C., Lin, Y. -C., Linde, F., Linker, S. D., Littenberg, T. B., Liu, A., Liu, G. C., Liu, Jian, Villarreal, F. Llamas, Llobera-Querol, J., Lo, R. K. L., Locquet, J. -P., London, L. T., Longo, A., Lopez, D., Portilla, M. Lopez, Lorenzini, M., Lorenzo-Medina, A., Loriette, V., Lormand, M., Losurdo, G., Lott IV, T. P., Lough, J. D., Loughlin, H. A., Lousto, C. O., Lowry, M. J., Lu, N., Lück, H., Lumaca, D., Lundgren, A. P., Lussier, A. W., Ma, L. -T., Ma, S., Ma'arif, M., Macas, R., Macedo, A., MacInnis, M., Maciy, R. R., Macleod, D. M., MacMillan, I. A. O., Macquet, A., Macri, D., Maeda, K., Maenaut, S., Hernandez, I. Magaña, Magare, S. S., Magazzù, C., Magee, R. M., Maggio, E., Maggiore, R., Magnozzi, M., Mahesh, M., Mahesh, S., Maini, M., Majhi, S., Majorana, E., Makarem, C. N., Makelele, E., Malaquias-Reis, J. A., Mali, U., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mannix, B., Mansell, G. L., Mansingh, G., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Pina, D. Marín, Marion, F., Márka, S., Márka, Z., Markosyan, A. S., Markowitz, A., Maros, E., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, B. B., Martinez, M., Martinez, V., Martini, A., Martinovic, K., Martins, J. C., Martynov, D. V., Marx, E. J., Massaro, L., Masserot, A., Masso-Reid, M., Mastrodicasa, M., Mastrogiovanni, S., Matcovich, T., Matiushechkina, M., Matsuyama, M., Mavalvala, N., Maxwell, N., McCarrol, G., McCarthy, R., McClelland, D. E., McCormick, S., McCuller, L., McEachin, S., McElhenny, C., McGhee, G. I., McGinn, J., McGowan, K. B. M., McIver, J., McLeod, A., McRae, T., Meacher, D., Meijer, Q., Melatos, A., Mellaerts, S., Menendez-Vazquez, A., Menoni, C. S., Mera, F., Mercer, R. A., Mereni, L., Merfeld, K., Merilh, E. L., Mérou, J. R., Merritt, J. D., Merzougui, M., Messenger, C., Messick, C., Meyer-Conde, M., Meylahn, F., Mhaske, A., Miani, A., Miao, H., Michaloliakos, I., Michel, C., Michimura, Y., Middleton, H., Miller, A. L., Miller, S., Millhouse, M., Milotti, E., Milotti, V., Minenkov, Y., Mio, N., Mir, Ll. M., Mirasola, L., Miravet-Tenés, M., Miritescu, C. -A., Mishra, A. K., Mishra, A., Mishra, C., Mishra, T., Mitchell, A. L., Mitchell, J. G., Mitra, S., Mitrofanov, V. P., Mittleman, R., Miyakawa, O., Miyamoto, S., Miyoki, S., Mo, G., Mobilia, L., Mohapatra, S. R. P., Mohite, S. R., Molina-Ruiz, M., Mondal, C., Mondin, M., Montani, M., Moore, C. J., Moraru, D., More, A., More, S., Moreno, G., Morgan, C., Morisaki, S., Moriwaki, Y., Morras, G., Moscatello, A., Mourier, P., Mours, B., Mow-Lowry, C. M., Muciaccia, F., Mukherjee, Arunava, Mukherjee, D., Mukherjee, Samanwaya, Mukherjee, Soma, Mukherjee, Subroto, Mukherjee, Suvodip, Mukund, N., Mullavey, A., Munch, J., Mundi, J., Mungioli, C. L., Oberg, W. R. Munn, Murakami, Y., Murakoshi, M., Murray, P. G., Muusse, S., Nabari, D., Nadji, S. L., Nagar, A., Nagarajan, N., Nagler, K. N., Nakagaki, K., Nakamura, K., Nakano, H., Nakano, M., Nandi, D., Napolano, V., Narayan, P., Nardecchia, I., Narikawa, T., Narola, H., Naticchioni, L., Nayak, R. K., Neilson, J., Nelson, A., Nelson, T. J. N., Nery, M., Neunzert, A., Ng, S., Quynh, L. Nguyen, Nichols, S. A., Nielsen, A. B., Nieradka, G., Niko, A., Nishino, Y., Nishizawa, A., Nissanke, S., Nitoglia, E., Niu, W., Nocera, F., Norman, M., North, C., Novak, J., Siles, J. F. Nuño, Nuttall, L. K., Obayashi, K., Oberling, J., O'Dell, J., Oertel, M., Offermans, A., Oganesyan, G., Oh, J. J., Oh, K., O'Hanlon, T., Ohashi, M., Ohkawa, M., Ohme, F., Oliveira, A. S., Oliveri, R., O'Neal, B., Oohara, K., O'Reilly, B., Ormsby, N. D., Orselli, M., O'Shaughnessy, R., O'Shea, S., Oshima, Y., Oshino, S., Ossokine, S., Osthelder, C., Ota, I., Ottaway, D. J., Ouzriat, A., Overmier, H., Owen, B. J., Pace, A. E., Pagano, R., Page, M. A., Pai, A., Pal, A., Pal, S., Palaia, M. A., Pálfi, M., Palma, P. P., Palomba, C., Palud, P., Pan, H., Pan, J., Pan, K. C., Panai, R., Panda, P. K., Pandey, S., Panebianco, L., Pang, P. T. H., Pannarale, F., Pannone, K. A., Pant, B. C., Panther, F. H., Paoletti, F., Paolone, A., Papalexakis, E. E., Papalini, L., Papigkiotis, G., Paquis, A., Parisi, A., Park, B. -J., Park, J., Parker, W., Pascale, G., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passenger, L., Passuello, D., Patane, O., Pathak, D., Pathak, M., Patra, A., Patricelli, B., Patron, A. S., Paul, K., Paul, S., Payne, E., Pearce, T., Pedraza, M., Pegna, R., Pele, A., Arellano, F. E. Peña, Penn, S., Penuliar, M. D., Perego, A., Pereira, Z., Perez, J. J., Périgois, C., Perna, G., Perreca, A., Perret, J., Perriès, S., Perry, J. W., Pesios, D., Petracca, S., Petrillo, C., Pfeiffer, H. P., Pham, H., Pham, K. A., Phukon, K. S., Phurailatpam, H., Piarulli, M., Piccari, L., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierini, L., Pierra, G., Pierro, V., Pietrzak, M., Pillas, M., Pilo, F., Pinard, L., Pinto, I. M., Pinto, M., Piotrzkowski, B. J., Pirello, M., Pitkin, M. D., Placidi, A., Placidi, E., Planas, M. L., Plastino, W., Poggiani, R., Polini, E., Pompili, L., Poon, J., Porcelli, E., Porter, E. K., Posnansky, C., Poulton, R., Powell, J., Pracchia, M., Pradhan, B. K., Pradier, T., Prajapati, A. K., Prasai, K., Prasanna, R., Prasia, P., Pratten, G., Principe, G., Principe, M., Prodi, G. A., Prokhorov, L., Prosposito, P., Puecher, A., Pullin, J., Punturo, M., Puppo, P., Pürrer, M., Qi, H., Qin, J., Quéméner, G., Quetschke, V., Quigley, C., Quinonez, P. J., Raab, F. J., Raabith, S. S., Raaijmakers, G., Raja, S., Rajan, C., Rajbhandari, B., Ramirez, K. E., Vidal, F. A. Ramis, Ramos-Buades, A., Rana, D., Ranjan, S., Ransom, K., Rapagnani, P., Ratto, B., Rawat, S., Ray, A., Raymond, V., Razzano, M., Read, J., Payo, M. Recaman, Regimbau, T., Rei, L., Reid, S., Reitze, D. H., Relton, P., Renzini, A. I., Rettegno, P., Revenu, B., Reyes, R., Rezaei, A. S., Ricci, F., Ricci, M., Ricciardone, A., Richardson, J. W., Richardson, M., Rijal, A., Riles, K., Riley, H. K., Rinaldi, S., Rittmeyer, J., Robertson, C., Robinet, F., Robinson, M., Rocchi, A., Rolland, L., Rollins, J. G., Romano, A. E., Romano, R., Romero, A., Romero-Shaw, I. M., Romie, J. H., Ronchini, S., Roocke, T. J., Rosa, L., Rosauer, T. J., Rose, C. A., Rosińska, D., Ross, M. P., Rossello, M., Rowan, S., Roy, S. K., Roy, S., Rozza, D., Ruggi, P., Ruhama, N., Morales, E. Ruiz, Ruiz-Rocha, K., Sachdev, S., Sadecki, T., Sadiq, J., Saffarieh, P., Sah, M. R., Saha, S. S., Saha, S., Sainrat, T., Menon, S. Sajith, Sakai, K., Sakellariadou, M., Sakon, S., Salafia, O. S., Salces-Carcoba, F., Salconi, L., Saleem, M., Salemi, F., Sallé, M., Salvador, S., Sanchez, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sänger, E. M., Santoliquido, F., Saravanan, T. R., Sarin, N., Sasaoka, S., Sasli, A., Sassi, P., Sassolas, B., Satari, H., Sathyaprakash, B. S., Sato, R., Sato, Y., Sauter, O., Savage, R. L., Sawada, T., Sawant, H. L., Sayah, S., Scacco, V., Schaetzl, D., Scheel, M., Schiebelbein, A., Schiworski, M. G., Schmidt, P., Schmidt, S., Schnabel, R., Schneewind, M., Schofield, R. M. S., Schouteden, K., Schulte, B. W., Schutz, B. F., Schwartz, E., Scialpi, M., Scott, J., Scott, S. M., Seetharamu, T. C., Seglar-Arroyo, M., Sekiguchi, Y., Sellers, D., Sengupta, A. S., Sentenac, D., Seo, E. G., Seo, J. W., Sequino, V., Serra, M., Servignat, G., Sevrin, A., Shaffer, T., Shah, U. S., Shaikh, M. A., Shao, L., Sharma, A. K., Sharma, P., Sharma-Chaudhary, S., Shaw, M. R., Shawhan, P., Shcheblanov, N. S., Sheridan, E., Shikano, Y., Shikauchi, M., Shimode, K., Shinkai, H., Shiota, J., Shoemaker, D. H., Shoemaker, D. M., Short, R. W., ShyamSundar, S., Sider, A., Siegel, H., Sieniawska, M., Sigg, D., Silenzi, L., Simmonds, M., Singer, L. P., Singh, A., Singh, D., Singh, M. K., Singh, S., Singha, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, L., Smith, R. J. E., Smith, W. J., Soldateschi, J., Somiya, K., Song, I., Soni, K., Soni, S., Sordini, V., Sorrentino, F., Sorrentino, N., Sotani, H., Soulard, R., Southgate, A., Spagnuolo, V., Spencer, A. P., Spera, M., Spinicelli, P., Spoon, J. B., Sprague, C. A., Srivastava, A. K., Stachurski, F., Steer, D. A., Steinlechner, J., Steinlechner, S., Stergioulas, N., Stevens, P., Stevenson, S., StPierre, M., Stratta, G., Strong, M. D., Strunk, A., Sturani, R., Stuver, A. L., Suchenek, M., Sudhagar, S., Sueltmann, N., Suleiman, L., Sullivan, K. D., Sun, L., Sunil, S., Suresh, J., Sutton, P. J., Suzuki, T., Suzuki, Y., Swinkels, B. L., Syx, A., Szczepańczyk, M. J., Szewczyk, P., Tacca, M., Tagoshi, H., Tait, S. C., Takahashi, H., Takahashi, R., Takamori, A., Takase, T., Takatani, K., Takeda, H., Takeshita, K., Talbot, C., Tamaki, M., Tamanini, N., Tanabe, D., Tanaka, K., Tanaka, S. J., Tanaka, T., Tang, D., Tanioka, S., Tanner, D. B., Tao, L., Tapia, R. D., Martín, E. N. Tapia San, Tarafder, R., Taranto, C., Taruya, A., Tasson, J. D., Teloi, M., Tenorio, R., Themann, H., Theodoropoulos, A., Thirugnanasambandam, M. P., Thomas, L. M., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tissino, J., Tiwari, A., Tiwari, P., Tiwari, S., Tiwari, V., Todd, M. R., Toivonen, A. M., Toland, K., Tolley, A. E., Tomaru, T., Tomita, K., Tomura, T., Tong, H., Tong-Yu, C., Toriyama, A., Toropov, N., Torres-Forné, A., Torrie, C. I., Toscani, M., Melo, I. Tosta e, Tournefier, E., Trapananti, A., Travasso, F., Traylor, G., Trevor, M., Tringali, M. C., Tripathee, A., Troian, G., Troiano, L., Trovato, A., Trozzo, L., Trudeau, R. J., Tsang, T. T. L., Tsuchida, S., Tsukada, L., Tsutsui, T., Turbang, K., Turconi, M., Turski, C., Ubach, H., Uchikata, N., Uchiyama, T., Udall, R. P., Uehara, T., Uematsu, M., Ueno, K., Ueno, S., Undheim, V., Ushiba, T., Vacatello, M., Vahlbruch, H., Vaidya, N., Vajente, G., Vajpeyi, A., Valdes, G., Valencia, J., Valentini, M., Vallejo-Peña, S. A., Vallero, S., Valsan, V., van Bakel, N., van Beuzekom, M., van Dael, M., Brand, J. F. J. van den, Broeck, C. Van Den, Vander-Hyde, D. C., van der Sluys, M., Van de Walle, A., van Dongen, J., Vandra, K., van Haevermaet, H., van Heijningen, J. V., Van Hove, P., VanKeuren, M., Vanosky, J., van Putten, M. H. P. M., van Ranst, Z., van Remortel, N., Vardaro, M., Vargas, A. F., Varghese, J. J., Varma, V., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venikoudis, S., Venneberg, J., Verdier, P., Verkindt, D., Verma, B., Verma, P., Verma, Y., Vermeulen, S. M., Vetrano, F., Veutro, A., Vibhute, A. M., Viceré, A., Vidyant, S., Viets, A. D., Vijaykumar, A., Vilkha, A., Villa-Ortega, V., Vincent, E. T., Vinet, J. -Y., Viret, S., Virtuoso, A., Vitale, S., Vives, A., Vocca, H., Voigt, D., von Reis, E. R. G., von Wrangel, J. S. A., Vyatchanin, S. P., Wade, L. E., Wade, M., Wagner, K. J., Wajid, A., Walker, M., Wallace, G. S., Wallace, L., Wang, H., Wang, J. Z., Wang, W. H., Wang, Z., Waratkar, G., Warner, J., Was, M., Washimi, T., Washington, N. Y., Watarai, D., Wayt, K. E., Weaver, B. R., Weaver, B., Weaving, C. R., Webster, S. A., Weinert, M., Weinstein, A. J., Weiss, R., Wellmann, F., Wen, L., Weßels, P., Wette, K., Whelan, J. T., Whiting, B. F., Whittle, C., Wildberger, J. B., Wilk, O. S., Wilken, D., Wilkin, A. T., Willadsen, D. J., Willetts, K., Williams, D., Williams, M. J., Williams, N. S., Willis, J. L., Willke, B., Wils, M., Winterflood, J., Wipf, C. C., Woan, G., Woehler, J., Wofford, J. K., Wolfe, N. E., Wong, H. T., Wong, H. W. Y., Wong, I. C. F., Wright, J. L., Wright, M., Wu, C., Wu, D. S., Wu, H., Wuchner, E., Wysocki, D. M., Xu, V. A., Xu, Y., Yadav, N., Yamamoto, H., Yamamoto, K., Yamamoto, T. S., Yamamoto, T., Yamamura, S., Yamazaki, R., Yan, S., Yan, T., Yang, F. W., Yang, F., Yang, K. Z., Yang, Y., Yarbrough, Z., Yasui, H., Yeh, S. -W., Yelikar, A. B., Yin, X., Yokoyama, J., Yokozawa, T., Yoo, J., Yu, H., Yuan, S., Yuzurihara, H., Zadrożny, A., Zanolin, M., Zeeshan, M., Zelenova, T., Zendri, J. -P., Zeoli, M., Zerrad, M., Zevin, M., Zhang, A. C., Zhang, L., Zhang, R., Zhang, T., Zhang, Y., Zhao, C., Zhao, Yue, Zhao, Yuhang, Zheng, Y., Zhong, H., Zhou, R., Zhu, X. -J., Zhu, Z. -H., Zimmerman, A. B., Zucker, M. E., and Zweizig, J.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
We report the observation of a coalescing compact binary with component masses $2.5\text{-}4.5~M_\odot$ and $1.2\text{-}2.0~M_\odot$ (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth observing run of the LIGO-Virgo-KAGRA detector network on 2023 May 29 by the LIGO Livingston Observatory. The primary component of the source has a mass less than $5~M_\odot$ at 99% credibility. We cannot definitively determine from gravitational-wave data alone whether either component of the source is a neutron star or a black hole. However, given existing estimates of the maximum neutron star mass, we find the most probable interpretation of the source to be the coalescence of a neutron star with a black hole that has a mass between the most massive neutron stars and the least massive black holes observed in the Galaxy. We provisionally estimate a merger rate density of $55^{+127}_{-47}~\text{Gpc}^{-3}\,\text{yr}^{-1}$ for compact binary coalescences with properties similar to the source of GW230529_181500; assuming that the source is a neutron star-black hole merger, GW230529_181500-like sources constitute about 60% of the total merger rate inferred for neutron star-black hole coalescences. The discovery of this system implies an increase in the expected rate of neutron star-black hole mergers with electromagnetic counterparts and provides further evidence for compact objects existing within the purported lower mass gap., Comment: 45 pages (10 pages author list, 13 pages main text, 1 page acknowledgements, 13 pages appendices, 8 pages bibliography), 17 figures, 16 tables. Update to match version published in The Astrophysical Journal Letters. Data products available from https://zenodo.org/records/10845779
- Published
- 2024
- Full Text
- View/download PDF
32. 90K/Mac-2 BP Is a New Predictive Biomarker of Response to Infliximab Therapy in IBD Patients
- Author
-
Pasqua Letizia Pesole, Marina Liso, Rossella Donghia, Vito Guerra, Antonio Lippolis, Mauro Mastronardi, and Palma Aurelia Iacovazzi
- Subjects
inflammatory bowel disease ,90K/Mac-2 BP ,galectin-3 binding protein ,infliximab ,biological drug ,biomarkers ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Inflammatory bowel diseases (IBD), comprising Crohn’s disease (CD) and Ulcerative Colitis (UC), are multifactorial disorders characterized by a chronic inflammatory status with the secretion of cytokines and immune mediators. Biologic drugs targeting pro-inflammatory cytokines, such as infliximab, are broadly used in the treatment of IBD patients, but some patients lose responsiveness after an initial success. The research into new biomarkers is crucial for advancing personalized therapies and monitoring the response to biologics. The aim of this single center, observational study is to analyze the relationship between serum levels of 90K/Mac-2 BP and the response to infliximab, in a cohort of 48 IBD patients (30 CD and 18 UC), enrolled from February 2017 to December 2018. In our IBD cohort, high 90K serum levels were found at baseline in patients who then developed anti-infliximab antibodies at the fifth infusion (22 weeks after the first), becoming non-responders (9.76 ± 4.65 µg/mL compared to 6.53 ± 3.29 µg/mL in responder patients, p = 0.005). This difference was significant in the total cohort and in CD, but not significant in UC. We then analyzed the relationship between serum levels of 90K, C-reactive protein (CRP), and Fecal calprotectin. A significant positive correlation was found at baseline between 90K and CRP, the most common serum inflammation marker (R = 0.42, p = 0.0032). We concluded that circulating 90K could be considered a new non-invasive biomarker for monitoring the response to infliximab. Furthermore, 90K serum level determination, before the first infliximab infusion, in association with other inflammatory markers such as CRP, could assist in the choice of biologics for the treatment of IBD patients, thereby obviating the need for a drug switch due to loss of response, and so improving clinical practice and patient care.
- Published
- 2023
- Full Text
- View/download PDF
33. Enantiospecificity in NMR enabled by chirality-induced spin selectivity.
- Author
-
Georgiou, T, Palma, J, Mujica, V, Varela, S, Galante, M, Santamaría-García, V, Mboning, L, Schwartz, R, Cuniberti, G, and Bouchard, L-S
- Abstract
Spin polarization in chiral molecules is a magnetic molecular response associated with electron transport and enantioselective bond polarization that occurs even in the absence of an external magnetic field. An unexpected finding by Santos and co-workers reported enantiospecific NMR responses in solid-state cross-polarization (CP) experiments, suggesting a possible additional contribution to the indirect nuclear spin-spin coupling in chiral molecules induced by bond polarization in the presence of spin-orbit coupling. Herein we provide a theoretical treatment for this phenomenon, presenting an effective spin-Hamiltonian for helical molecules like DNA and density functional theory (DFT) results on amino acids that confirm the dependence of J-couplings on the choice of enantiomer. The connection between nuclear spin dynamics and chirality could offer insights for molecular sensing and quantum information sciences. These results establish NMR as a potential tool for chiral discrimination without external agents.
- Published
- 2024
34. Investigation of the genetic aetiology of Lewy body diseases with and without dementia
- Author
-
Wu, Lesley Yue, Real, Raquel, Martinez-Carrasco, Alejandro, Chia, Ruth, Lawton, Michael A, Shoai, Maryam, Bresner, Catherine, Blauwendraat, Cornelis, Singleton, Andrew B, Ryten, Mina, Abramzon, Yevgeniya, Ahmed, Sarah, Alba, Camille, Albert, Marilyn S, Bacikova, Dagmar, Barrett, Matthew J, Beach, Thomas G, Bennett, David A, Besser, Lilah M, Bigio, Eileen H, Boeve, Bradley F, Bohannan, Ryan C, Caraway, Chad A, Palma, Jose-Alberto, Dalgard, Clifton L, Dickson, Dennis, Ding, Jinhui, Faber, Kelley, Ferman, Tanis, Ferrucci, Luigi, Flanagan, Margaret E, Foroud, Tatiana M, Ghetti, Bernardino, Gibbs, J Raphael, Goate, Alison, Goldstein, David, Graff-Radford, Neill R, Hu, Heng-Chen, Hupalo, Daniel, Kaiser, Scott M, Kaufmann, Horacio, Kim, Ronald C, Klein, Gregory, Kukull, Walter, Kuzma, Amanda, Leverenz, James, Lopez, Grisel, Mao, Qinwen, Martinez-McGrath, Elisa, Masliah, Eliezer, Monuki, Ed, Newell, Kathy L, Norcliffe-Kaufmann, Lucy, Perkins, Matthew, Pletnikova, Olga, Renton, Alan E, Resnick, Susan M, Ross, Owen A, Sabir, Marya S, Scherzer, Clemens R, Scholz, Sonja W, Serrano, Geidy, Shakkotai, Vikram, Sidransky, Ellen, Tanaka, Toshiko, Tayebi, Nahid, Traynor, Bryan J, Troncoso, Juan C, Viollet, Coralie, Walton, Ronald L, Woltjer, Randy, Wszolek, Zbigniew K, Black, Sandra E, Gan-Or, Ziv, Keith, Julia, Masellis, Mario, Rogaeva, Ekaterina, Aarsland, Dag, Al-Sarraj, Safa, Attems, Johannes, Ferrari, Raffaele, Gentleman, Steve, Hardy, John A, Hodges, Angela K, Love, Seth, McKeith, Ian, Morris, Christopher M, Morris, Huw R, Palmer, Laura, Pickering-Brown, Stuart, Reynolds, Regina H, Thomas, Alan J, Tilley, Bension S, Troakes, Claire, Brett, Francesca, Brice, Alexis, and Duyckaerts, Charles
- Subjects
Biomedical and Clinical Sciences ,Biological Psychology ,Clinical Sciences ,Neurosciences ,Psychology ,Neurodegenerative ,Genetics ,Prevention ,Aging ,Lewy Body Dementia ,Brain Disorders ,Dementia ,Alzheimer's Disease Related Dementias (ADRD) ,Parkinson's Disease ,Human Genome ,Acquired Cognitive Impairment ,Clinical Research ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,2.1 Biological and endogenous factors ,Neurological ,International Lewy Body Dementia Genomics Consortium ,APOE ,Lewy body diseases ,dementia ,genome-wide association studies ,Clinical sciences ,Biological psychology - Abstract
Up to 80% of Parkinson's disease patients develop dementia, but time to dementia varies widely from motor symptom onset. Dementia with Lewy bodies presents with clinical features similar to Parkinson's disease dementia, but cognitive impairment precedes or coincides with motor onset. It remains controversial whether dementia with Lewy bodies and Parkinson's disease dementia are distinct conditions or represent part of a disease spectrum. The biological mechanisms underlying disease heterogeneity, in particular the development of dementia, remain poorly understood, but will likely be the key to understanding disease pathways and, ultimately, therapy development. Previous genome-wide association studies in Parkinson's disease and dementia with Lewy bodies/Parkinson's disease dementia have identified risk loci differentiating patients from controls. We collated data for 7804 patients of European ancestry from Tracking Parkinson's, The Oxford Discovery Cohort, and Accelerating Medicine Partnership-Parkinson's Disease Initiative. We conducted a discrete phenotype genome-wide association study comparing Lewy body diseases with and without dementia to decode disease heterogeneity by investigating the genetic drivers of dementia in Lewy body diseases. We found that risk allele rs429358 tagging APOEe4 increases the odds of developing dementia, and that rs7668531 near the MMRN1 and SNCA-AS1 genes and an intronic variant rs17442721 tagging LRRK2 G2019S on chromosome 12 are protective against dementia. These results should be validated in autopsy-confirmed cases in future studies.
- Published
- 2024
35. Enantiospecificity in NMR Enabled by Chirality-Induced Spin Selectivity
- Author
-
Georgiou, T., Palma, J. L., Mujica, V., Varela, S., Galante, M., Garcıa, V. Santamarıa, Mboning, L., Schwartz, R. N., Cuniberti, G., and Bouchard, L. -S.
- Subjects
Condensed Matter - Soft Condensed Matter ,Physics - Biological Physics ,Physics - Chemical Physics - Abstract
Spin polarization in chiral molecules is a magnetic molecular response associated with electron transport and enantioselective bond polarization that occurs even in the absence of an external magnetic field. An unexpected finding by Santos and co-workers reported enantiospecific NMR responses in solid-state cross-polarization (CP) experiments, suggesting a possible additional contribution to the indirect nuclear spin-spin coupling in chiral molecules induced by bond polarization in the presence of spin-orbit coupling. Herein we provide a theoretical treatment for this phenomenon, presenting an effective spin-Hamiltonian for helical molecules like DNA and density functional theory (DFT) results on amino acids that confirm the dependence of J-couplings on the choice of enantiomer. The connection between nuclear spin dynamics and chirality could offer insights for molecular sensing and quantum information sciences. These results establish NMR as a potential tool for chiral discrimination without external agents., Comment: 102 pages, 16 figures, 40 tables
- Published
- 2024
36. Constraints on the energy spectrum of the diffuse cosmic neutrino flux from the ANTARES neutrino telescope
- Author
-
ANTARES Collaboration, Albert, A., Alves, S., André, M., Ardid, M., Ardid, S., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Becherini, Y., Belhorma, B., Bendahman, M., Benfenati, F., Bertin, V., Biagi, S., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Carenini, F., Carr, J., Carretero, V., Cartraud, T., Celli, S., Cerisy, L., Chabab, M., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coelho, J. A. B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Díaz, A. F., De Martino, B., Distefano, C., Di Palma, I., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Eddymaoui, A., van Eeden, T., van Eijk, D., Hedri, S. El, Khayati, N. El, Enzenhöfer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L. A., Gagliardini, S., García, J., Oliver, C. Gatius, Gay, P., Geißelbrecht, N., Glotin, H., Gozzini, R., Ruiz, R. Gracia, Graf, K., Guidi, C., Haegel, L., van Haren, H., Heijboer, A. J., Hello, Y., Hennig, L., Hernández-Rey, J. J., Hößl, J., Huang, F., Illuminati, G., Jisse-Jung, B., de Jong, M., de Jong, P., Kadler, M., Kalekin, O., Katz, U., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Lamoureux, M., Lazo, A., Lefèvre, D., Leonora, E., Levi, G., Stum, S. Le, Loucatos, S., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Migliozzi, P., Moussa, A., Muller, R., Navas, S., Nezri, E., Fearraigh, B. Ó, Oukacha, E., Păun, A., Păvălaş, G. E., Peña-Martínez, S., Perrin-Terrin, M., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Real, D., Riccobene, G., Romanov, A., Losa, A. Sánchez, Saina, A., Greus, F. Salesa, Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schüssler, F., Seneca, J., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Vallage, B., Vannoye, G., Van Elewyck, V., Viola, S., Vivolo, D., Wilms, J., Zavatarelli, S., Zegarelli, A., Zornoza, J. D., and Zúñiga, J.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
High-significance evidences of the existence of a high-energy diffuse flux of cosmic neutrinos have emerged in the last decade from several observations by the IceCube Collaboration. The ANTARES neutrino telescope took data for 15 years in the Mediterranean Sea, from 2007 to 2022, and collected a high-purity all-flavour neutrino sample. The search for a diffuse cosmic neutrino signal using this dataset is presented in this article. This final analysis did not provide a statistically significant observation of the cosmic diffuse flux. However, this is converted into limits on the properties of the cosmic neutrino spectrum. In particular, given the sensitivity of the ANTARES neutrino telescope between 1 and 50 TeV, constraints on single-power-law hypotheses are derived for the cosmic diffuse flux below 20 TeV, especially for power-law fits of the IceCube data with spectral index softer than 2.8.
- Published
- 2024
- Full Text
- View/download PDF
37. The VISTA Variables in the V\'ia L\'actea eXtended (VVVX) ESO public survey: Completion of the observations and legacy
- Author
-
Saito, R. K., Hempel, M., Alonso-García, J., Lucas, P. W., Minniti, D., Alonso, S., Baravalle, L., Borissova, J., Caceres, C., Chené, A. N., Cross, N. J. G., Duplancic, F., Garro, E. R., Gómez, M., Ivanov, V. D., Kurtev, R., Luna, A., Majaess, D., Navarro, M. G., Pullen, J. B., Rejkuba, M., Sanders, J. L., Smith, L. C., Albino, P. H. C., Alonso, M. V., Amôres, E. B., Angeloni, R., Arias, J. I., Arnaboldi, M., Barbuy, B., Bayo, A., Beamin, J. C., Bedin, L. R., Bellini, A., Benjamin, R. A., Bica, E., Bonatto, C. J., Botan, E., Braga, V. F., Brown, D. A., Cabral, J. B., Camargo, D., Garatti, A. Caratti o, Carballo-Bello, J. A., Catelan, M., Chavero, C., Chijani, M. A., Clariá, J. J., Coldwell, G. V., Peña, C. Contreras, Ramos, R. Contreras, Corral-Santana, J. M., Cortés, C. C., Cortés-Contreras, M., Cruz, P., Daza-Perilla, I. V., Debattista, V. P., Dias, B., Donoso, L., D'Souza, R., Emerson, J. P., Federle, S., Fermiano, V., Fernandez, J., Fernández-Trincado, J. G., Ferreira, T., Lopes, C. E. Ferreira, Firpo, V., Flores-Quintana, C., Fraga, L., Froebrich, D., Galdeano, D., Gavignaud, I., Geisler, D., Gerhard, O. E., Gieren, W., Gonzalez, O. A., Gramajo, L. V., Gran, F., Granitto, P. M., Griggio, M., Guo, Z., Gurovich, S., Hilker, M., Jones, H. R. A., Kammers, R., Kuhn, M. A., Kumar, M. S . N., Kundu, R., Lares, M., Libralato, M., Lima, E., Maccarone, T. J., Cortés, P. Marchant, Martin, E. L., Masetti, N., Matsunaga, N., Mauro, F., McDonald, I., Mejías, A., Mesa, V., Milla-Castro, F. P., Minniti, J. H., Bidin, C. Moni, Montenegro, K., Morris, C., Motta, V., Navarete, F., Molina, C. Navarro, Nikzat, F., Castellón, J. L. Nilo, Obasi, C., Ortigoza-Urdaneta, M., Palma, T., Parisi, C., Ramírez, K. Pena, Pereyra, L., Perez, N., Petralia, I., Pichel, A., Pignata, G., Alegría, S. Ramírez, Rojas, A. F., Rojas, D., Roman-Lopes, A., Rovero, A. C., Saroon, S., Schmidt, E. O., Schröder, A. C., Schultheis, M., Sgró, M. A., Solano, E., Soto, M., Stecklum, B., Steeghs, D., Tamura, M., Tissera, P., Valcarce, A. A. R., Valotto, C. A., Vasquez, S., Villalon, C., Villanova, S., Cádiz, F. Vivanco, Bacigalupo, R. Zelada, Zijlstra, A., and Zoccali, M.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The ESO public survey VISTA Variables in the V\'ia L\'actea (VVV) surveyed the inner Galactic bulge and the adjacent southern Galactic disk from $2009-2015$. Upon its conclusion, the complementary VVV eXtended (VVVX) survey has expanded both the temporal as well as spatial coverage of the original VVV area, widening it from $562$ to $1700$ sq. deg., as well as providing additional epochs in $JHK_{\rm s}$ filters from $2016-2023$. With the completion of VVVX observations during the first semester of 2023, we present here the observing strategy, a description of data quality and access, and the legacy of VVVX. VVVX took $\sim 2000$ hours, covering about 4% of the sky in the bulge and southern disk. VVVX covered most of the gaps left between the VVV and the VISTA Hemisphere Survey (VHS) areas and extended the VVV time baseline in the obscured regions affected by high extinction and hence hidden from optical observations. VVVX provides a deep $JHK_{\rm s}$ catalogue of $\gtrsim 1.5\times10^9$ point sources, as well as a $K_{\rm s}$ band catalogue of $\sim 10^7$ variable sources. Within the existing VVV area, we produced a $5D$ map of the surveyed region by combining positions, distances, and proper motions of well-understood distance indicators such as red clump stars, RR Lyrae, and Cepheid variables. In March 2023 we successfully finished the VVVX survey observations that started in 2016, an accomplishment for ESO Paranal Observatory upon 4200 hours of observations for VVV+VVVX. The VVV+VVVX catalogues complement those from the Gaia mission at low Galactic latitudes and provide spectroscopic targets for the forthcoming ESO high-multiplex spectrographs MOONS and 4MOST., Comment: 17 pages, 11 figures (+ appendix). Accepted for publication in Astronomy and Astrophysics in section 14: Catalogs and data
- Published
- 2024
38. Quantum Extreme Learning of molecular potential energy surfaces and force fields
- Author
-
Monaco, Gabriele Lo, Bertini, Marco, Lorenzo, Salvatore, and Palma, G. Massimo
- Subjects
Quantum Physics - Abstract
Quantum machine learning algorithms are expected to play a pivotal role in quantum chemistry simulations in the immediate future. One such key application is the training of a quantum neural network to learn the potential energy surface and force field of molecular systems. We address this task by using the quantum extreme learning machine paradigm. This particular supervised learning routine allows for resource-efficient training, consisting of a simple linear regression performed on a classical computer. We have tested a setup that can be used to study molecules of any dimension and is optimized for immediate use on NISQ devices with a limited number of native gates. We have applied this setup to three case studies: lithium hydride, water, and formamide, carrying out both noiseless simulations and actual implementation on IBM quantum hardware. Compared to other supervised learning routines, the proposed setup requires minimal quantum resources, making it feasible for direct implementation on quantum platforms, while still achieving a high level of predictive accuracy compared to simulations. Our encouraging results pave the way towards the future application to more complex molecules, being the proposed setup scalable., Comment: 14 pages, 7 figures. Accepted on Machine Learning: Science and Technology
- Published
- 2024
- Full Text
- View/download PDF
39. On the evolution of low-mass central galaxies in the vicinity of massive structures
- Author
-
Palma, Daniela, Lacerna, Ivan, Artale, M. Celeste, Montero-Dorta, Antonio D., Ruiz, Andrés N., Cora, Sofía A., Rodriguez, Facundo, Pallero, Diego, O'Mill, Ana, and Choque-Challapa, Nelvy
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We investigate low-mass central galaxies with Mstar = $10^{9.5}-10^{10}$ Msun/h, located near massive groups and galaxy clusters using the TNG300 and MDPL2-SAG simulations. We set out to study their evolution, aiming to find hints about the large-scale conformity signal they produce. We also use a control sample of low-mass central galaxies located far away from massive structures. For both samples, we find a sub-population of galaxies that were accreted by another halo in the past but are now considered central galaxies; we refer to these objects as former satellites. The fraction of former satellites is higher for quenched central galaxies near massive systems: 45% in TNG300 and 17% in MDPL2-SAG. Our results in TNG300 show that former satellites were typically hosted by massive dark matter halos (M200 $\geq 10^{13}$ Msun/h) at z$\sim$0.3, followed by a drop in halo mass at lower redshifts. In addition, we find a strong drop in the total gas mass at z$\leq$1 for quenched central galaxies near galaxy groups and clusters produced by these former satellites as well. By removing former satellites, the evolution of quenched central galaxies is fairly similar to those of the quenched control galaxies, showing small differences at low-z. For MDPL2-SAG, former satellites were hosted by less massive halos, with a mean halo mass around $10^{11}$ Msun/h, and the evolution remains equal before and after removing former satellites. We also measure the two-halo conformity, i.e., the correlation in the specific SFR between low-mass central galaxies and their neighbors at Mpc scales, and how former satellites contribute to the signal at z=0, 0.3, and 1. The conformity signal decreases from z=0 to z=1 in MDPL2-SAG but it increases in TNG300. However, after removing former satellites in TNG300, the signal is strongly reduced but almost does not change at z$\leq$0.3, and it disappears at z=1 (abridged)., Comment: 16 pages, 13 figures, submitted to A&A
- Published
- 2024
40. Viscous Unified Dark Matter Models Under Scrutiny: Uncovering Inconsistencies from Dynamical System Analysis
- Author
-
Palma, Guillermo, Gomez, Gabriel, and Cruz, Norman
- Subjects
General Relativity and Quantum Cosmology ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Viscous unified dark matter models aim to describe the dark sector of the Universe, as the dark matter fluid itself gives rise to an accelerated expansion due to a negative bulk viscous pressure. However, in most studies, radiation is often disregarded as a minor factor in dynamical system analyses, overlooking whether radiation domination is achievable. In this paper, we rigorously examine this critical aspect for common parameterizations of bulk viscosity, denoted as $\xi$, within two general classes of viscous unified models. Our findings reveal significant inconsistencies in models where $\xi \propto H^{1-2s} \rho_{m}^{s}$ with $s\leq 0$, and surprisingly, in models where $\xi \propto \rho_{m}^{s}$ with exponents $s<0$, as they both fail to produce a radiation-dominated era. Moreover, the exponent $s$ must lye within the interval $0 \leq s < 1/2$ for the latter model to correctly describes the cosmological evolution. These results underscore the need of including these constraints as a prior in statistical analyses of observational data, with implications for current statistical inferences for the second model, where both prior and best-fit values of $s$ often fall outside the acceptable range., Comment: 20 page
- Published
- 2024
41. Towards a Function-as-a-Service Choreographic Programming Language: Examples and Applications
- Author
-
De Palma, Giuseppe, Giallorenzo, Saverio, Mauro, Jacopo, Trentin, Matteo, and Zavattaro, Gianluigi
- Subjects
Computer Science - Programming Languages ,Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Choreographic Programming (CP) is a language paradigm whereby software artefacts, called choreographies, specify the behaviour of communicating participants. CP is famous for its correctness-by-construction approach to the development of concurrent, distributed systems. In this paper, we illustrate FaaSChal, a proposal for a CP language tailored for the case of serverless Function-as-a-Service (FaaS). In FaaS, developers define a distributed architecture as a collection of stateless functions, leaving to the serverless platform the management of deployment and scaling. We provide a first account of a CP language tailored for the FaaS case via examples that present some of its relevant features, including projection. In addition, we showcase a novel application of CP. We use the choreography as a source to extract information on the infrastructural relations among functions so that we can synthesise policies that strive to minimise their latency while guaranteeing the respect of user-defined constraints.
- Published
- 2024
42. Regularizing infrared divergences in de Sitter spacetime
- Author
-
Huenupi, Javier, Hughes, Ellie, Palma, Gonzalo A., and Sypsas, Spyros
- Subjects
High Energy Physics - Theory ,Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Phenomenology - Abstract
Correlation functions of light scalars in de Sitter space, computed in standard perturbation theory, are hindered by time-dependent infrared divergences in the form of powers of $\ln a(t)$, where $a(t)$ is the scale factor describing the expansion of space. It has often been pointed out that loop corrections to these correlation functions make their divergence even stronger. In this note, we argue that this is not the case: Loop corrections can be treated systematically with standard perturbative techniques (such as dimensional regularization) without necessarily introducing new $\ln a(t)$ dependencies. To be concrete, we focus on correlation functions represented by diagrams with a single vertex and an arbitrary number of loops. In this case, divergences from loops can be removed systematically with counterterms order by order, and one finds that observable loop-corrected correlation functions are indistinguishable from their tree-level form. By adopting a Wilsonian perspective, we further point out that our results favor the use of physical cutoffs (as opposed to comoving cutoffs) to regularize infrared divergences in general diagrams with an arbitrary number of loops and vertices., Comment: 11 pages + references. Comments welcome
- Published
- 2024
43. Search for photons above 10$^{18}$ eV by simultaneously measuring the atmospheric depth and the muon content of air showers at the Pierre Auger Observatory
- Author
-
The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., do, J. A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fenu, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Johnsen, J. A., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lu, L., Luce, Q., Lundquist, J. P., Payeras, A. Machado, Majercakova, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reininghaus, M., Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. Rodrigues, Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Smau, R., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Pierre Auger Observatory is the most sensitive instrument to detect photons with energies above $10^{17}$ eV. It measures extensive air showers generated by ultra high energy cosmic rays using a hybrid technique that exploits the combination of a fluorescence detector with a ground array of particle detectors. The signatures of a photon-induced air shower are a larger atmospheric depth of the shower maximum ($X_{max}$) and a steeper lateral distribution function, along with a lower number of muons with respect to the bulk of hadron-induced cascades. In this work, a new analysis technique in the energy interval between 1 and 30 EeV (1 EeV = $10^{18}$ eV) has been developed by combining the fluorescence detector-based measurement of $X_{max}$ with the specific features of the surface detector signal through a parameter related to the air shower muon content, derived from the universality of the air shower development. No evidence of a statistically significant signal due to photon primaries was found using data collected in about 12 years of operation. Thus, upper bounds to the integral photon flux have been set using a detailed calculation of the detector exposure, in combination with a data-driven background estimation. The derived 95% confidence level upper limits are 0.0403, 0.01113, 0.0035, 0.0023, and 0.0021 km$^{-2}$ sr$^{-1}$ yr$^{-1}$ above 1, 2, 3, 5, and 10 EeV, respectively, leading to the most stringent upper limits on the photon flux in the EeV range. Compared with past results, the upper limits were improved by about 40% for the lowest energy threshold and by a factor 3 above 3 EeV, where no candidates were found and the expected background is negligible. The presented limits can be used to probe the assumptions on chemical composition of ultra-high energy cosmic rays and allow for the constraint of the mass and lifetime phase space of super-heavy dark matter particles., Comment: 19 pages, 22 figures
- Published
- 2024
44. Measurement of the Depth of Maximum of Air-Shower Profiles with energies between $\mathbf{10^{18.5}}$ and $\mathbf{10^{20}}$ eV using the Surface Detector of the Pierre Auger Observatory and Deep Learning
- Author
-
The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., do, J. A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fenu, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Johnsen, J. A., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lu, L., Luce, Q., Lundquist, J. P., Payeras, A. Machado, Majercakova, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reininghaus, M., Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. Rodrigues, Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Smau, R., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We report an investigation of the mass composition of cosmic rays with energies from 3 to 100 EeV (1 EeV=$10^{18}$ eV) using the distributions of the depth of shower maximum $X_\mathrm{max}$. The analysis relies on ${\sim}50,000$ events recorded by the Surface Detector of the Pierre Auger Observatory and a deep-learning-based reconstruction algorithm. Above energies of 5 EeV, the data set offers a 10-fold increase in statistics with respect to fluorescence measurements at the Observatory. After cross-calibration using the Fluorescence Detector, this enables the first measurement of the evolution of the mean and the standard deviation of the $X_\mathrm{max}$ distributions up to 100 EeV. Our findings are threefold: (1.) The evolution of the mean logarithmic mass towards a heavier composition with increasing energy can be confirmed and is extended to 100 EeV. (2.) The evolution of the fluctuations of $X_\mathrm{max}$ towards a heavier and purer composition with increasing energy can be confirmed with high statistics. We report a rather heavy composition and small fluctuations in $X_\mathrm{max}$ at the highest energies. (3.) We find indications for a characteristic structure beyond a constant change in the mean logarithmic mass, featuring three breaks that are observed in proximity to the ankle, instep, and suppression features in the energy spectrum., Comment: submitted to Phys. Rev. D, 28 pages, 18 figures, 5 tables
- Published
- 2024
45. Inference of the Mass Composition of Cosmic Rays with energies from $\mathbf{10^{18.5}}$ to $\mathbf{10^{20}}$ eV using the Pierre Auger Observatory and Deep Learning
- Author
-
The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., do, J. A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fenu, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Johnsen, J. A., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lu, L., Luce, Q., Lundquist, J. P., Payeras, A. Machado, Majercakova, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reininghaus, M., Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. Rodrigues, Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Smau, R., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present measurements of the atmospheric depth of the shower maximum $X_\mathrm{max}$, inferred for the first time on an event-by-event level using the Surface Detector of the Pierre Auger Observatory. Using deep learning, we were able to extend measurements of the $X_\mathrm{max}$ distributions up to energies of 100 EeV ($10^{20}$ eV), not yet revealed by current measurements, providing new insights into the mass composition of cosmic rays at extreme energies. Gaining a 10-fold increase in statistics compared to the Fluorescence Detector data, we find evidence that the rate of change of the average $X_\mathrm{max}$ with the logarithm of energy features three breaks at $6.5\pm0.6~(\mathrm{stat})\pm1~(\mathrm{sys})$ EeV, $11\pm 2~(\mathrm{stat})\pm1~(\mathrm{sys})$ EeV, and $31\pm5~(\mathrm{stat})\pm3~(\mathrm{sys})$ EeV, in the vicinity to the three prominent features (ankle, instep, suppression) of the cosmic-ray flux. The energy evolution of the mean and standard deviation of the measured $X_\mathrm{max}$ distributions indicates that the mass composition becomes increasingly heavier and purer, thus being incompatible with a large fraction of light nuclei between 50 EeV and 100 EeV., Comment: submitted to Phys. Rev. Lett., 10 pages, 3 figures, 1 table
- Published
- 2024
46. Modeling the spatial resolution of magnetic solitons in Magnetic Force Microscopy and the effect on their sizes
- Author
-
Castro, I., Riveros, A., Palma, J. L., Abelmann, L., Tomasello, R., Rodrigues, D. R., Giordano, A., Finocchio, G., Gallardo, R., and Vidal-Silva, N.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science - Abstract
In this work, we explored theoretically the spatial resolution of magnetic solitons and the variations of their sizes when subjected to a Magnetic Force Microscopy (MFM) measurement. Next to tip-sample separation, we considered reversal in the magnetization direction of the tip, showing that the magnetic soliton size measurement can be strongly affected by the magnetization direction of the tip. In addition to previous studies that only consider thermal fluctuations, we developed a theoretical method to obtain the minimum observable length of a magnetic soliton and its length variation due to the influence of the MFM tip by minimizing the soliton's magnetic energy. Our model uses analytical and numerical calculations and prevents overestimating the characteristic length scales from MFM images. We compared our method with available data from MFM measurements of domain wall widths, and we performed micromagnetic simulations of a skyrmion-tip system, finding a good agreement for both attractive and repulsive domain wall profile signals and for the skyrmion diameter in the presence of the magnetic tip. Our results provide significant insights for a better interpretation of MFM measurements of different magnetic solitons and will be helpful in the design of potential reading devices based on magnetic solitons as information carriers., Comment: 18 pages. Supplementary Material is included
- Published
- 2024
47. The polarized photon distribution function
- Author
-
de Florian, Daniel, Conte, Lucas Palma, and Volonnino, Gabriel Fernando
- Subjects
High Energy Physics - Phenomenology - Abstract
We employ the LuxQED approach to compute the polarized photon PDF (photon pPDF). This approach expresses the pPDF in terms of the structure functions $g_1$ and $g_2$. Different models for the structure functions are employed according to the parameter space region. The resulting pPDF is approximately of the order of $x$ times the unpolarized PDF. The relative uncertainty in the photon pPDF reaches up to $50\%$ for $x \sim 10^{-3}$, decreasing to approximately $10\%$ for higher values of $x$. The computation of the photon pPDF will be essential for improving the precision of polarized calculations and will have fundamental implications for studies at the future Electron-Ion Collider (EIC).
- Published
- 2024
48. FunLess: Functions-as-a-Service for Private Edge Cloud Systems
- Author
-
De Palma, Giuseppe, Giallorenzo, Saverio, Mauro, Jacopo, Trentin, Matteo, and Zavattaro, Gianluigi
- Subjects
Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
We present FunLess, a Function-as-a-Service (FaaS) platform tailored for the private edge cloud system. FunLess responds to recent trends that advocate for extending the coverage of serverless computing to private edge cloud systems and enhancing latency, security, and privacy while improving resource usage. Unlike existing solutions that rely on containers for function invocation, FunLess leverages WebAssembly (Wasm) as its runtime environment. Wasm's lightweight, sandboxed runtime is crucial to have functions run on constrained devices at the edge. Moreover, the advantages of using Wasm in FunLess include a consistent development and deployment environment for users and function portability (write once, run everywhere) We validate FunLess under different deployment scenarios, characterised by the presence/absence of constrained-resource devices (Raspberry Pi 3B+) and the (in)accessibility of container orchestration technologies - Kubernetes. We compare FunLess with three production-ready, widely adopted open-source FaaS platforms - OpenFaaS, Fission, and Knative. Our benchmarks confirm that FunLess is a proper solution for FaaS private edge cloud systems since it achieves performance comparable to the considered FaaS alternatives while it is the only fully-deployable alternative on constrained-resource devices, thanks to its small memory footprint.
- Published
- 2024
49. Investigating pump harmonics generation in a SNAIL-based Traveling Wave Parametric Amplifier
- Author
-
Levochkina, A. Yu., Ahmad, H. G., Mastrovito, P., Chatterjee, I., Serpico, G., Di Palma, L., Ferroiuolo, R., Satariano, R., Darvehi, P., Ranadive, A., Cappelli, G., Gal, G. Le, Planat, L., Montemurro, D., Massarotti, D., Tafuri, F., Roch, N., Pepe, G. P., and Esposito, M.
- Subjects
Quantum Physics - Abstract
Traveling Wave Parametric Amplifiers (TWPAs) are extensively employed in experiments involving weak microwave signals for their highly desirable quantum-limited and broadband characteristics. However, TWPAs' broadband nature comes with the disadvantage of admitting the activation of spurious nonlinear processes, such as harmonics generation, that can potentially degrade amplification performance. Here we experimentally investigate a Josephson TWPA device with SNAIL (Superconducting Nonlinear Asymmetric Inductive Element)-based unit cells focusing on the amplification behaviour along with the generation of second and third harmonics of the pump. By comparing experimental results with transient numerical simulations, we demonstrate the influence of Josephson junctions' fabrication imperfections on the occurrence of harmonics and on the gain behaviour., Comment: typos fixed
- Published
- 2024
50. Interaction and adiabatic evolution of orthodromic and antidromic impulses in the axoplasmic fluid
- Author
-
Pavón-Torres, O., Agüero-Granados, M. A., and Maguiña-Palma, M. E.
- Subjects
Nonlinear Sciences - Pattern Formation and Solitons - Abstract
Unlike expected from the Hodgkin-Huxley model predictions, in which there is annihilation once orthodromic and antidromic impulses collide, the Heimburg-Jackson model demonstrates that both impulses penetrate each other as it has been shown experimentally. These impulses can be depicted as low amplitude nonlinear excitations in a weakly dissipative soliton model described by the damped NLSE. In view of the above, the Karpman-Solov'ev-Maslov perturbation theory turns out to be ideal to study the interaction and adiabatic evolution of orthodromic and antidromic impulses once axoplasmic fluid is present.
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.