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1,823 results on '"Palmieri V"'

1. Epigenetic Therapies for Heart Failure: Current Insights and Future Potential

Author

Napoli C, Bontempo P, Palmieri V, Coscioni E, Maiello C, Donatelli F, and Benincasa G

Subjects
heart failure, personalized therapy, epidrugs., Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Claudio Napoli,1 Paola Bontempo,2 Vittorio Palmieri,3 Enrico Coscioni,4 Ciro Maiello,5 Francesco Donatelli,6 Giuditta Benincasa1 1Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, 80138, Italy; 2Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, 80138, Italy; 3Department of Cardiac Surgery and Transplantation, Heart Transplantation Unit in Adults of the ‘Ospedali dei Colli Monaldi-Cotugno-CTO’, Naples, Italy; 4Department of Cardiac Surgery, Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy; 5Department of Cardiovascular Surgery and Transplants, Monaldi Hospital, Azienda dei Colli, Naples, Italy; 6Chair of Cardiac Surgery, Department of Cardiothoracic Center, Istituto Clinico Sant’Ambrogio, University of Milan, Milan, ItalyCorrespondence: Giuditta BenincasaDepartment of Advanced Medical and Surgical Sciences (DAMSS), University of Campania “Luigi Vanvitelli”, Naples, ItalyTel +390815667916Email giuditta.benincasa@unicampania.itAbstract: Despite the current reductionist approach providing an optimal indication for diagnosis and treatment of patients with heart failure with reduced ejection fraction (HFrEF), there are no standard pharmacological therapies for heart failure with preserved ejection fraction (HFpEF). Although in its infancy in cardiovascular diseases, the epigenetic-based therapy (“epidrugs”) is capturing the interest of physician community. In fact, an increasing number of controlled clinical trials is evaluating the putative beneficial effects of: 1) direct epigenetic-oriented drugs, eg, apabetalone, and 2) repurposed drugs with a possible indirect epigenetic interference, eg, metformin, statins, sodium glucose transporter inhibitors 2 (SGLT2i), and omega 3 polyunsaturated fatty acids (PUFAs) in both HFrEF and HFpEF, separately. Apabetalone is the first and unique direct epidrug tested in cardiovascular patients to date, and the BETonMACE trial has reported a reduction in first HF hospitalization (any EF value) and cardiovascular death in patients with type 2 diabetes and recent acute coronary syndrome, suggesting a possible role in secondary prevention. Patients with HFpEF seem to benefit from supplementation to the standard therapy with statins, metformin, and SGLT2i owing to their ability in reducing mortality. In contrast, the vasodilator hydralazine, with or without isosorbide dinitrate, did not provide beneficial effects. In HFrEF, metformin and SGLT2i could reduce the risk of incident HF and mortality in affected patients whereas clinical trials based on statins provided mixed results. Furthermore, PUFAs diet supplementation was significantly associated with reduced cardiovascular risk in both HFpEF and HFrEF. Future large trials will reveal whether direct and indirect epitherapy will remain a work in progress or become a useful way to customize the therapy in the real-world management of HFpEF and HFrEF. Our goal is to discuss the recent advancement in the epitherapy as a possible way to improve personalized therapy of HF.Keywords: heart failure, personalized therapy, epidrugs

Published
2021

2. Synthesis and characterization of different immunogenic viral nanoconstructs from rotavirus VP6 inner capsid protein

Author

Bugli F, Caprettini V, Cacaci M, Martini C, Paroni Sterbini F, Torelli R, Della Longa S, Papi M, Palmieri V, Giardina B, Posteraro B, Sanguinetti M, and Arcovito A

Subjects
Medicine (General), R5-920
Abstract

Francesca Bugli,1 Valeria Caprettini,2 Margherita Cacaci,1 Cecilia Martini,1 Francesco Paroni Sterbini,1 Riccardo Torelli,1 Stefano Della Longa,3 Massimiliano Papi,4 Valentina Palmieri,4 Bruno Giardina,5 Brunella Posteraro,1 Maurizio Sanguinetti,1 Alessandro Arcovito5 1Istituto di Microbiologia, Università Cattolica del Sacro Cuore, 2Dipartimento di Fisica, Sapienza Università di Roma, Rome, 3Dipartimento di Medicina Clinica, Sanità Pubblica, Scienze della Vita e dell’Ambiente, Università dell’Aquila, L’Aquila, 4Istituto di Fisica, 5Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy Abstract: In order to deliver low-cost viral capsomeres from a large amount of soluble viral VP6 protein from human rotavirus, we developed and optimized a biotechnological platform in Escherichia coli. Specifically, three different expression protocols were compared, differing in their genetic constructs, ie, a simple native histidine-tagged VP6 sequence, VP6 fused to thioredoxin, and VP6 obtained with the newly described small ubiquitin-like modifier (SUMO) fusion system. Our results demonstrate that the histidine-tagged protein does not escape the accumulation in the inclusion bodies, and that SUMO is largely superior to the thioredoxin-fusion tag in enhancing the expression and solubility of VP6 protein. Moreover, the VP6 protein produced according to the SUMO fusion tag displays well-known assembly properties, as observed in both transmission electron microscopy and atomic force microscopy images, giving rise to either VP6 trimers, 60 nm spherical virus-like particles, or nanotubes a few micron long. This different quaternary organization of VP6 shows a higher level of immunogenicity for the elongated structures with respect to the spheres or the protein trimers. Therefore, the expression and purification strategy presented here – providing a large amount of the viral capsid protein in the native form with relatively simple, rapid, and economical procedures – opens a new route toward large-scale production of a more efficient antigenic compound to be used as a vaccination tool or as an adjuvant, as well as represents a top-quality biomaterial to be further modified for biotechnological purposes. Keywords: Virus-like particles, protein-based nanotubes, SUMO fusion tag, human rotavirus vaccine

Published
2014

3. Optical rogue waves in spheroids of tumor cells

Author

Pierangeli, D., Perini, G., Palmieri, V., Grecco, I., Friggeri, G., Papi, M., DelRe, E., and Conti, C.

Subjects
Physics - Optics, Nonlinear Sciences - Pattern Formation and Solitons, Physics - Applied Physics, Physics - Biological Physics
Abstract

Rogue waves are intense and unexpected wavepackets ubiquitous in complex systems. In optics, they are promising as robust and noise-resistant beams for probing and manipulating the underlying material. Localizing large optical power is crucial especially in biomedical systems, where, however, extremely intense beams have not yet been observed. We here discover that tumor-cell spheroids manifest optical rogue waves when illuminated by randomly modulated laser beams. The intensity of light transmitted through bio-printed three-dimensional tumor models follows a signature Weibull statistical distribution, where extreme events correspond to spatially-localized optical modes propagating within the cell network. Experiments varying the input beam power and size indicate the rogue waves have a nonlinear origin. We show these optical filaments form high-transmission channels with enhanced transmission. They deliver large optical power through the tumor spheroid, which can be exploited to achieve a local temperature increase controlled by the input wave shape. Our findings shed new light on optical propagation in biological aggregates and demonstrate how extreme event formation allows light concentration in deep tissues, paving the way to using rogue waves in biomedical applications such as light-activated therapies.

Published
2023

4. The CUORE and CUORE-0 experiments at LNGS

Author

D’Addabbo A., Alduino C., Alfonso K., Artusa D. R., Avignone F. T., Azzolini O., Banks T. I., Bari G., Beeman J.W., Bellini F., Bersani A., Biassoni M., Branca A., Brofferio C., Bucci C., Camacho A., Caminata A., Canonica L., Cao X. G., Capelli S., Cappelli L., Carbone L., Cardani L., Carniti P., Casali N., Cassina L., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., Cushman J. S., Dafinei I., Davis C. J., Dell’Oro S., Deninno M. M., Di Domizio S., Di Vacri M. L., Drobizhev A., Fang D. Q., Faverzani M., Fernandes G., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gladstone L., Gorla P., Gotti C., Gutierrez T. D., Haller E. E., Han K., Hansen E., Heeger K. M., Hennings-Yeomans R., Hickerson K. P., Huang H. Z., Kadel R., Keppel G., Kolomensky Yu. G., Leder A., Ligi C., Lim K. E., Liu X., Ma Y. G., Maino M., Marini L., Martinez M., Maruyama R. H., Mei Y., Moggi N., Morganti S., Mosteiro P. J., Napolitano T., Nones C., Norman E. B., Nucciotti A., O’Donnell T., Orio F., Ouellet J. L., Pagliarone C. E., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Rosenfeld C., Rusconi C., Sangiorgio S., Santone D., Scielzo N.D., Singh V., Sisti M., Smith A. R., Taffarello L., Tenconi M., Terranova F., Tomei C., Trentalange S., Vignati M., Wagaarachchi S. L., Wang B. S., Wang H. W., Wilson J., Winslow L. A., Wise T., Woodcraft A., Zanotti L., Zhang G. Q., Zhu B. X., Zimmermann S., and Zucchelli S.

Subjects
Physics, QC1-999
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is a 1-ton scale bolometric experiment devoted to the search of the neutrinoless double-beta decay (0νββ) in 130Te. The CUORE detector consists of an array of 988 TeO2 crystals operated at 10 mK. CUORE-0 is the CUORE demonstrator: it has been built to test the performance of the upcoming CUORE experiment and represents the largest 130Te bolometric setup ever operated. CUORE-0 has been running at Laboratori Nazionali del Gran Sasso (Italy) from 2013 to 2015. The final CUORE-0 analysis on 0νββ and the corresponding detector performance are presented. The present status of the CUORE experiment, now in its final construction and commissioning phase, are discussed. The results from assembly of the detector and the commissioning of the cryostat are reported.

Published
2017
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5. Neutrinoless double-beta decay search with CUORE and CUORE-0 experiments

Author

Moggi N., Artusa D. R., Avignone F. T., Azzolini O., Balata M., Banks T. I., Bari G., Beeman J., Bellini F., Bersani A., Biassoni M., Brofferio C., Bucci C., Cai X. Z., Camacho A., Caminata A., Canonica L., Cao X. G., Capelli S., Cappelli L., Carbone L., Cardani L., Casali N., Cassina L., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., Cushman J. S., Dafinei I., Dally A., Datskov V., Dell’oro S., Deninno M. M., Di Domizio S., Di Vacri M. L., Drobizhev A., Ejzak L., Fang D. Q., Farach H. A., Faverzani M., Fernandes G., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T. D., Haller E. E., Han K., Heeger K. M., Hennings-Yeomans R., Hickerson K. P., Huang H. Z., Kadel R., Keppel G., Kolomensky Yu. G., Li Y. L., Ligi C., Lim K. E., Liu X., Ma Y. G., Maiano C., Maino M., Martinez M., Maruyama R. H., Mei Y., Morganti S., Napolitano T., Nisi S., Nones C., Norman E. B., Nucciotti A., O’Donnell T., Orio F., Orlandi D., Ouellet J. L., Pagliarone C. E., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Rosenfeld C., Rusconi C., Sala E., Sangiorgio S., Santone D., Scielzo N. D., Sisti M., Smith A. R., Taffarello L., Tenconi M., Terranova F., Tian W. D., Tomei C., Trentalange S., Ventura G., Vignati M., Wang B. S., Wang H. W., Wielgus L., Wilson J., Winslow L. A., Wise T., Woodcraft A., Zanotti L., Zarra C., Zhang G. Q., Zhu B. X., and Zucchelli S.

Subjects
Physics, QC1-999
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for the neutrinoless double-beta decays. Observation of the process would unambiguously establish that neutrinos are Majorana particles and provide information on their absolute mass scale hierarchy. CUORE is now under construction and will consist of an array of 988 TeO2 crystal bolometers operated at 10 mK, but the first tower (CUORE-0) is already taking data. The experimental techniques used will be presented as well as the preliminary CUORE-0 results. The current status of the full-mass experiment and its expected sensitivity will then be discussed.

Published
2015
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6. CUORE Opens the Door to Tonne-scale Cryogenics Experiments

Author

CUORE Collaboration, Adams, D. Q., Alduino, C., Alessandria, F., Alfonso, K., Andreotti, E., Avignone III, F. T., Azzolini, O., Balata, M., Bandac, I., Banks, T. I., Bari, G., Barucci, M., Beeman, J. W., Bellini, F., Benato, G., Beretta, M., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Cariello, M., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Celi, E., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Datskov, V., Davis, C. J., Del Corso, F., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Dompè, V., Di Vacri, M. L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Gaigher, R., Ghislandi, S., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Guetti, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E. V., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, R. G., Huang, H. Z., Iannone, M., Ioannucci, L., Johnston, J., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, R., Ma, L., Ma, Y. G., Maiano, C., Maino, M., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R. H., Mayer, D., Mazza, R., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Olcese, M., Olivieri, E., Orio, F., Orlandi, D., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rossi, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Smith, A. R., Speller, D., Stivanello, F., Surukuchi, P. T., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Ventura, G., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wallig, J., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined., Comment: 45 pages, 14 figures

Published
2021
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7. Initial performance of the CUORE detector

Author

Cushman, JS, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

CUORE, the Cryogenic Underground Observatory for Rare Events, is an experiment searching for the neutrinoless double-beta decay of 130Te. The first CUORE dataset was acquired in May and June 2017 and consisted of 10.6 kg-yr of TeO2 exposure, with several days of calibration data before and after the physics dataset. We discuss here the initial performance of the CUORE detector and cryostat in this first dataset.

Published
2020

8. First results from the CUORE experiment

Author

Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Dompe, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

CUORE (Cryogenic Underground Observatory for Rare Events) is a ton-scale experiment aiming to the search of neutrino-less double beta decay in 130Te with a projected sensitivity on the Majorana effective mass close to the inverted hierarchy region. The CUORE detector consists of a segmented array of 988 TeO2 bolometers, organized in 19 towers and operated at a temperature of about 10 mK thanks to a custom cryogenic system which, besides the uncommon scale, observes several constraints from the radio-purity of the materials to the mechanical decoupling of the cooling systems. The successful commissioning of the CUORE cryogenic system has been completed early in 2016 and represents an outstanding achievement by itself. The installation of the detector proceeded along 2016 followed by the cooldown to base temperature at the beginning of 2017. The CUORE detector is now operational and has been taking science data since Spring 2017. With the first ∼3 weeks of collected data, we present here the most stringent constraint on the 130Te half-live for the neutrino-less double beta decay.

Published
2020

9. Deep optical neural network by living tumour brain cells

Author

Pierangeli, D., Palmieri, V., Marcucci, G., Moriconi, C., Perini, G., De Spirito, M., Papi, M., and Conti, C.

Subjects
Physics - Medical Physics, Condensed Matter - Disordered Systems and Neural Networks, Nonlinear Sciences - Adaptation and Self-Organizing Systems, Physics - Biological Physics, Physics - Optics
Abstract

The new era of artificial intelligence demands large-scale ultrafast hardware for machine learning. Optical artificial neural networks process classical and quantum information at the speed of light, and are compatible with silicon technology, but lack scalability and need expensive manufacturing of many computational layers. New paradigms, as reservoir computing and the extreme learning machine, suggest that disordered and biological materials may realize artificial neural networks with thousands of computational nodes trained only at the input and at the readout. Here we employ biological complex systems, i.e., living three-dimensional tumour brain models, and demonstrate a random neural network (RNN) trained to detect tumour morphodynamics via image transmission. The RNN, with the tumour spheroid as a three-dimensional deep computational reservoir, performs programmed optical functions and detects cancer morphodynamics from laser-induced hyperthermia inaccessible by optical imaging. Moreover, the RNN quantifies the effect of chemotherapy inhibiting tumour growth. We realize a non-invasive smart probe for cytotoxicity assay, which is at least one order of magnitude more sensitive with respect to conventional imaging. Our random and hybrid photonic/living system is a novel artificial machine for computing and for the real-time investigation of tumour dynamics., Comment: 14 pages, 4 figures

Published
2018

10. Double-beta decay of ${}^{130}$Te to the first $0^+$ excited state of ${}^{130}$Xe with CUORE-0

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nastasi, M., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

We report on a search for double beta decay of $^{130}$Te to the first $0^{+}$ excited state of $^{130}$Xe using a 9.8 kg$\cdot$yr exposure of $^{130}$Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double-decay modes. We find no evidence for either mode and place lower bounds on the half-lives: $\tau^{0\nu}_{0^+}>7.9\cdot 10^{23}$ yr and $\tau^{2\nu}_{0^+}>2.4\cdot 10^{23}$ yr. Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: $\tau^{0\nu}_{0^+}>1.4\cdot 10^{24}$ yr and $\tau^{2\nu}_{0^+}>2.5\cdot 10^{23}$ yr., Comment: 9 pages, 5 figures, 5 tables

Published
2018
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11. Update on the recent progress of the CUORE experiment

Author

CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Dompè, V., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Scielzo, N. D., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

CUORE is a 741 kg array of 988 TeO$_2$ bolometeric crystals designed to search for the neutrinoless double beta decay of $^{130}$Te and other rare processes. CUORE has been taking data since summer 2017, and as of summer 2018 collected a total of 86.3 kg$\cdot$yr of TeO$_2$ exposure. Based on this exposure, we were able to set a limit on the $0\nu\beta\beta$ half-life of $^{130}$Te of $T^{0\nu}_{1/2}>1.5\times10^{25}$ yr at 90% C.L. At this conference, we showed the decomposition of the CUORE background and were able to extract a $^{130}$Te $2\nu\beta\beta$ half-life of $T_{1/2}^{2\nu}=[7.9\pm0.1 \mathrm{(stat.)}\pm0.2 \mathrm{(syst.)}]\times10^{20}$ yr. This is the most precise measurement of this half-life and is consistent with previous measurements., Comment: Proceedings of the Neutrino 2018 Conference. 8 pages, 7 figures

Published
2018

12. Search of the neutrino-less double beta decay of $^{82}$Se into the excited states of $^{82}$Kr with CUPID-0

Author

Azzolini, O., Barrera, M. T., Beeman, J. W., Bellini, F., Beretta, M., Biassoni, M., Bossio, E., Brofferio, C., Bucci, C., Canonica, L., Capelli, S., Cardani, L., Carniti, P., Casali, N., Cassina, L., Clemenza, M., Cremonesi, O., Cruciani, A., D'Addabbo, A., Dafinei, I., Di Domizio, S., Ferroni, F., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Keppel, G., Martinez, M., Morganti, S., Nagorny, S., Nastasi, M., Nisi, S., Nones, C., Orlandi, D., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rusconi, C., Schaeffner, K., Tomei, C., Vignati, M., and Zolotarova, A.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

The CUPID0 experiment searches for double beta decay using cryogenic calorimeters with double (heat and light) read-out. The detector, consisting of 24 ZnSe crystals 95$\%$ enriched in $^{82}$Se and 2 natural ZnSe crystals, started data-taking in 2017 at Laboratori Nazionali del Gran Sasso. We present the search for the neutrino-less double beta decay of $^{82}$Se into the 0$_1^+$, 2$_1^+$ and 2$_2^+$ excited states of $^{82}$Kr with an exposure of 5.74 kg$\cdot$yr (2.24$\times$10$^{25}$ emitters$\cdot$yr). We found no evidence of the decays and set the most stringent limits on the widths of these processes: $\Gamma$($^{82}$Se $\rightarrow ^{82}$Kr$_{0_1^+}$)$<$8.55$\times$10$^{-24}$ yr$^{-1}$, $\Gamma$($^{82}$Se $\rightarrow ^{82}$Kr$_{2_1^+}$)$<6.25 \times10^{-24}$ yr$^{-1}$, $\Gamma$($^{82}$Se $\rightarrow ^{82}$Kr$_{2_2^+}$)$<$8.25$\times$10$^{-24}$ yr$^{-1}$ (90$\%$ credible interval

Published
2018
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13. Analysis of cryogenic calorimeters with light and heat read-out for double beta decay searches

Author

Azzolini, O., Barrera, M. T., Beeman, J. W., Bellini, F., Beretta, M., Biassoni, M., Bossio, E., Brofferio, C., Bucci, C., Canonica, L., Capelli, S., Cardani, L., Carniti, P., Casalia, N., Cassina, L., Clemenza, M., Cremonesi, O., Cruciani, A., D'Addabbo, A., Dafinei, I., Di Domizio, S., Ferroni, F., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Keppel, G., Martinez, M., Morganti, S., Nagorny, S., Nastasi, M., Nisi, S., Nones, C., Orlandi, D., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rusconi, C., Schäffner, K., Tomei, C., Vignati, M., and Zolotarova, A.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The suppression of spurious events in the region of interest for neutrinoless double beta decay will play a major role in next generation experiments. The background of detectors based on the technology of cryogenic calorimeters is expected to be dominated by {\alpha} particles, that could be disentangled from double beta decay signals by exploiting the difference in the emission of the scintillation light. CUPID-0, an array of enriched Zn$^{82}$Se scintillating calorimeters, is the first large mass demonstrator of this technology. The detector started data-taking in 2017 at the Laboratori Nazionali del Gran Sasso with the aim of proving that dual read-out of light and heat allows for an efficient suppression of the {\alpha} background. In this paper we describe the software tools we developed for the analysis of scintillating calorimeters and we demonstrate that this technology allows to reach an unprecedented background for cryogenic calorimeters., Comment: 11 pages, 9 figures

Published
2018
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14. First Result on the Neutrinoless Double Beta Decay of $^{82}$Se with CUPID-0

Author

collaboration, CUPID-0, Azzolini, O., Barrera, M. T., Beeman, J. W., Bellini, F., Beretta, M., Biassoni, M., Brofferio, C., Bucci, C., Canonica, L., Capelli, S., Cardani, L., Carniti, P., Casali, N., Cassina, L., Clemenza, M., Cremonesi, O., Cruciani, A., D'Addabbo, A., Dafinei, I., Di Domizio, S., Ferroni, F., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Keppel, G., Marini, L., Martinez, M., Morganti, S., Nagorny, S., Nastasi, M., Nisi, S., Nones, C., Orlandi, D., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Reindl, F., Rusconi, C., Schaeffner, K., Tomei, C., Vignati, M., and Zolotarova, A. S.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

We report the result of the search for neutrinoless double beta decay of $^{82}$Se obtained with CUPID-0, the first large array of scintillating Zn$^{82}$Se cryogenic calorimeters implementing particle identification. We observe no signal in a 1.83 kg yr $^{82}$Se exposure and we set the most stringent lower limit on the \onu $^{82}$Se half-life T$^{0\nu}_{1/2}>$ 2.4$\times \mathrm{10}^{24}$ yr (90\% credible interval), which corresponds to an effective Majorana neutrino mass m$_{\beta\beta} <$ (376-770) meV depending on the nuclear matrix element calculations. The heat-light readout provides a powerful tool for the rejection of \al\ particles and allows to suppress the background in the region of interest down to (3.6$^{+1.9}_{-1.4}$)$\times$10$^{-3}$\ckky, an unprecedented level for this technique.

Published
2018
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15. CUPID-0: the first array of enriched scintillating bolometers for 0\nu\beta\beta decay investigations

Author

Azzolini, O., Barrera, M. T., Beeman, J. W., Bellini, F., Beretta, M., Biassoni, M., Brofferio, C., Bucci, C., Canonica, L., Capelli, S., Cardani, L., Carniti, P., Casali, N., Cassina, L., Clemenza, M., Cremonesi, O., Cruciani, A., D'Addabbo, A., Dafinei, I., Di Domizio, S., Ferroni, F., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Keppel, G., Martinez, M., Morganti, S., Nagorny, S., Nastasi, M., Nisi, S., Nones, C., Orlandi, D., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Reindl, F., Rusconi, C., Schaeffner, K., Tomei, C., Vignati, M., and Zolotarova, A.

Subjects
Physics - Instrumentation and Detectors
Abstract

The CUPID-0 detector hosted at the Laboratori Nazionali del Gran Sasso, Italy, is the first large array of enriched scintillating cryogenic detectors for the investigation of $^{82}$Se neutrinoless double-beta decay (0$\nu\beta\beta$). CUPID-0 aims at measuring a background index in the region of interest (RoI) for 0$\nu\beta\beta$ at the level of 10$^{-3}$ c/keV/kg/y, the lowest value ever measured using cryogenic detectors. This result can be achieved by a state of the art technology for background suppression and thorough protocols and procedures for detector preparation and construction. In this paper, the different phases of the detector design and construction will be presented, from the material selection (for the absorber production) to the new and innovative detector structure. The successful construction of the detector lead to promising detector performance which are here preliminarily discussed

Published
2018
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16. Study of Rare Nuclear Processes with CUORE

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Dompè, V., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

TeO2 bolometers have been used for many years to search for neutrinoless double beta decay in 130-Te. CUORE, a tonne-scale TeO2 detector array, recently published the most sensitive limit on the half-life, $T_{1/2}^{0\nu} > 1.5 \times 10^{25}\,$yr, which corresponds to an upper bound of $140-400$~meV on the effective Majorana mass of the neutrino. While it makes CUORE a world-leading experiment looking for neutrinoless double beta decay, it is not the only study that CUORE will contribute to in the field of nuclear and particle physics. As already done over the years with many small-scale experiments, CUORE will investigate both rare decays (such as the two-neutrino double beta decay of 130-Te and the hypothesized electron capture in 123-Te), and rare processes (e.g., dark matter and axion interactions). This paper describes some of the achievements of past experiments that used TeO2 bolometers, and perspectives for CUORE., Comment: 36 pages, 13 figures, sumbitted to IJMPA Special Issue "Results and Developments in the investigation of rare nuclear decays and processes"

Published
2018

17. Double-beta decay of 130Te to the first 0+ excited state of 130Xe with CUORE-0

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone III, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Domizio, S Di, Vacri, ML Di, Drobizhev, A, Fang, DQ, Faverzani, M, Feintzeig, J, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Nucciotti, A, O’Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Subjects
nucl-ex, physics.ins-det, Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

We report on a search for double beta decay of $^{130}$Te to the first$0^{+}$ excited state of $^{130}$Xe using a 9.8 kg$\cdot$yr exposure of$^{130}$Te collected with the CUORE-0 experiment. In this work we exploitdifferent topologies of coincident events to search for both the neutrinolessand two-neutrino double-decay modes. We find no evidence for either mode andplace lower bounds on the half-lives: $\tau^{0\nu}_{0^+}>7.9\cdot 10^{23}$ yrand $\tau^{2\nu}_{0^+}>2.4\cdot 10^{23}$ yr. Combining our results with thoseobtained by the CUORICINO experiment, we achieve the most stringent constraintsavailable for these processes: $\tau^{0\nu}_{0^+}>1.4\cdot 10^{24}$ yr and$\tau^{2\nu}_{0^+}>2.5\cdot 10^{23}$ yr.

Published
2019

18. Double-beta decay of 130Te to the first 0 + excited state of 130Xe with CUORE-0

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone III, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Drobizhev, A, Fang, DQ, Faverzani, M, Feintzeig, J, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Nucciotti, A, O’Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Subjects
Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

We report on a search for double beta decay of 130Te to the first 0 + excited state of 130Xe using a 9.8kg·yr exposure of 130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: T01+0ν>7.9·1023yr and T01+2ν>2.4·1023yr (90%CL). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: T01+0ν>1.4·1024yr and T01+2ν>2.5·1023yr (90%CL).

Published
2019

19. CUORE: The first bolometric experiment at the ton scale for rare decay searches

Author

Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, and Santone, D

Subjects
Cryogenic, Superconductive Devices, Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in August 2016 and data taking started in spring 2017. In this contribution the achievement of the commissioning phase and the performance of the detector and the cryostat during the first physics run will be presented.

Published
2019

20. Results from the CUORE experiment

Author

Chiesa, D, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, and Schmidt, B

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta (0νββ) decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in 2016 and data taking started in 2017. In this conference we present the 0νββ decay results of CUORE from examining a total TeO2 exposure of 86.3 kg yr, characterized by an effective energy resolution of 7.7 keV FWHM and a background in the region of interest of 0.014 counts/(keV kg yr). Based on these data, CUORE places a lower limit on the 0νββ decay half-life of (90% C.L.). We then discuss the latest updates in the analysis of background and in the evaluation of the half-life of 2νββ decay of 130Te.

Published
2019

21. Results from the CUORE experiment

Author

Campani, A, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomansi, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, and Scielzo, ND

Subjects
Astronomy & Astrophysics
Abstract

Neutrinoless double beta decay (0νββ) is a rare, second-order nuclear transition that occurs only if neutrinos are massive Majorana particles or through new physics beyond Standard Model. This process explicitly violates the lepton number (L) by two units and, therefore, the observation of 0νββ would demonstrate that L is not a symmetry of nature. Combined with flavour mixing and cosmological measurements, it can provide unique contraints on neutrino mass scale and establish whether neutrinos are Dirac or Majorana particles. The Cryogenic Underground Observatory for Rare Events (CUORE) is an experiment located at the LNGS searching for 0νββ decay of 130Te. CUORE exploits the bolometric technique to reach high resolution around the Q-value (2527.5 keV). It consists of an array of 988 natural TeO2 cubic crystals grouped into 19 towers. With a total active mass of 742 kg (∼206 kg of 130Te), CUORE is operated at very low temperature with a new 3He/4He refrigerator. Data taking started at the beginning of 2017. After a brief introduction on the detector and the way data analysis is performed, I describe CUORE first results for the search of the 0νββ decay that were published in March 2018.

Published
2019

22. Double-beta decay of Xe with CUORE-0

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FTIII, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, S Di, Vacri, ML Di, Drobizhev, A, Fang, DQ, Faverzani, M, Feintzeig, J, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

We report on a search for double beta decay of 130Te to the first 0 + excited state of 130Xe using a 9.8kg·yr exposure of 130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: T01+0ν>7.9·1023yr and T01+2ν>2.4·1023yr (90%CL). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: T01+0ν>1.4·1024yr and T01+2ν>2.5·1023yr (90%CL).

Published
2019

23. Nitrogen dioxide pollution increases vulnerability to COVID-19 through altered immune function

Author

Di Ciaula, Agostino, Bonfrate, Leonilde, Portincasa, Piero, Appice, C, Belfiore, A, Binetti, M, Cafagna, G, Campanale, G, Carrieri, A, Cascella, G, Cataldi, S, Cezza, A, Ciannarella, M, Cicala, L, D’Alitto, F, Dell’Acqua, A, Dell’Anna, L, Diaferia, M, Erroi, G, Fiermonte, F, Galerati, I, Giove, M, Grimaldi, L, Mallardi, C, Mastrandrea, E, Mazelli, G. D., Mersini, G, Messina, G, Messina, M, Montesano, A, Noto, A, Novielli, M. E., Noviello, M, Palma, M. V., Palmieri, V. O., Passerini, F, Perez, F, Piro, C, Prigigallo, F, Pugliese, S, Rossi, O, Stasi, C, Stranieri, R, and Vitariello, G

Published
2022
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24. First Results from CUORE: A Search for Lepton Number Violation via $0\nu\beta\beta$ Decay of $^{130}$Te

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Andreotti, E., Arnaboldi, C., Avignone III, F. T., Azzolini, O., Bandac, I., Banks, T. I., Bari, G., Barucci, M., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biare, D., Biassoni, M., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Del Corso, F., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E. V., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Iannone, M., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maiano, C., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Olivieri, E., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pelosi, A., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Stivanello, F., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The CUORE experiment, a ton-scale cryogenic bolometer array, recently began operation at the Laboratori Nazionali del Gran Sasso in Italy. The array represents a significant advancement in this technology, and in this work we apply it for the first time to a high-sensitivity search for a lepton-number--violating process: $^{130}$Te neutrinoless double-beta decay. Examining a total TeO$_2$ exposure of 86.3 kg$\cdot$yr, characterized by an effective energy resolution of (7.7 $\pm$ 0.5) keV FWHM and a background in the region of interest of (0.014 $\pm$ 0.002) counts/(keV$\cdot$kg$\cdot$yr), we find no evidence for neutrinoless double-beta decay. The median statistical sensitivity of this search is $7.0\times10^{24}$ yr. Including systematic uncertainties, we place a lower limit on the decay half-life of $T^{0\nu}_{1/2}$($^{130}$Te) > $1.3\times 10^{25}$ yr (90% C.L.). Combining this result with those of two earlier experiments, Cuoricino and CUORE-0, we find $T^{0\nu}_{1/2}$($^{130}$Te) > $1.5\times 10^{25}$ yr (90% C.L.), which is the most stringent limit to date on this decay. Interpreting this result as a limit on the effective Majorana neutrino mass, we find $m_{\beta\beta}<(110 - 520)$ meV, where the range reflects the nuclear matrix element estimates employed., Comment: Published in PRL, reference and DOI added

Published
2017
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25. Search for Neutrinoless $\beta^{+}\hspace{-0.2em}EC$ Decay of $^{120}$Te with CUORE-0

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment
Abstract

We have performed a search for neutrinoless $\beta^{+}\hspace{-0.2em}EC$ decay of $^{120}$Te using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of $T_{1/2}>1.6\cdot10^{21}$ yr at $90\%$ CI. Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to $T_{1/2}>2.7\cdot10^{21}$ yr at $90\%$ CI., Comment: 10 pages, 6 figures, 3 tables

Published
2017
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26. Low Energy Analysis Techniques for CUORE

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Bari, G., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of $^{130}$Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below 60keV. Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils in CUORE-0., Comment: 11 pages, 6 figures

Published
2017

27. CUORE Sensitivity to $0\nu\beta\beta$ Decay

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

We report a study of the CUORE sensitivity to neutrinoless double beta ($0\nu\beta\beta$) decay. We used a Bayesian analysis based on a toy Monte Carlo (MC) approach to extract the exclusion sensitivity to the $0\nu\beta\beta$ decay half-life ($T_{1/2}^{0\nu}$) at $90\%$ credibility interval (CI) -- i.e. the interval containing the true value of $T_{1/2}^{0\nu}$ with $90\%$ probability -- and the $3 \sigma$ discovery sensitivity. We consider various background levels and energy resolutions, and describe the influence of the data division in subsets with different background levels. If the background level and the energy resolution meet the expectation, CUORE will reach a $90\%$ CI exclusion sensitivity of $2\cdot10^{25}$ yr with $3$ months, and $9\cdot10^{25}$ yr with $5$ years of live time. Under the same conditions, the discovery sensitivity after $3$ months and $5$ years will be $7\cdot10^{24}$ yr and $4\cdot10^{25}$ yr, respectively., Comment: 10 pages, 3 figures, 4 tables

Published
2017
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28. The projected background for the CUORE experiment

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., Zucchelli, S., and Laubenstein, M.

Subjects
Physics - Instrumentation and Detectors
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of 130Te with an array of 988 TeO2 bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90\% C.L. exclusion sensitivity on the \tect decay half-life of 9$\times$10$^{25}$ years after 5\,years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10$^{-2}$\,counts/keV/kg/y. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of 130Te is expected., Comment: 17 pages, 7 figures, matches published version

Published
2017
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30. Analysis of cryogenic calorimeters with light and heat read-out for double beta decay searches

Author

Azzolini, O, Barrera, MT, Beeman, JW, Bellini, F, Beretta, M, Biassoni, M, Bossio, E, Brofferio, C, Bucci, C, Canonica, L, Capelli, S, Cardani, L, Carniti, P, Casali, N, Cassina, L, Clemenza, M, Cremonesi, O, Cruciani, A, D’Addabbo, A, Dafinei, I, Domizio, S Di, Ferroni, F, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Keppel, G, Martinez, M, Morganti, S, Nagorny, S, Nastasi, M, Nisi, S, Nones, C, Orlandi, D, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rusconi, C, Schäffner, K, Tomei, C, Vignati, M, and Zolotarova, A

Subjects
physics.ins-det, nucl-ex, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics
Abstract

The suppression of spurious events in the region of interest for neutrinoless double beta decay will play a major role in next generation experiments. The background of detectors based on the technology of cryogenic calorimeters is expected to be dominated by α particles, that could be disentangled from double beta decay signals by exploiting the difference in the emission of the scintillation light. CUPID-0, an array of enriched Zn 82 Se scintillating calorimeters, is the first large mass demonstrator of this technology. The detector started data-taking in 2017 at the Laboratori Nazionali del Gran Sasso with the aim of proving that dual read-out of light and heat allows for an efficient suppression of the α background. In this paper we describe the software tools we developed for the analysis of scintillating calorimeters and we demonstrate that this technology allows to reach an unprecedented background for cryogenic calorimeters.

Published
2018

31. Update on the recent progress of the CUORE experiment

Author

Collaboration, CUORE, Adams, DQ, Alduino, C, Alfonso, K, III, FT Avignone, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, S Di, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, and Santone, D

Subjects
nucl-ex, hep-ex, physics.ins-det
Abstract

CUORE is a 741 kg array of 988 TeO$_2$ bolometeric crystals designed tosearch for the neutrinoless double beta decay of $^{130}$Te and other rareprocesses. CUORE has been taking data since summer 2017, and as of summer 2018collected a total of 86.3 kg$\cdot$yr of TeO$_2$ exposure. Based on thisexposure, we were able to set a limit on the $0u\beta\beta$ half-life of$^{130}$Te of $T^{0u}_{1/2}>1.5\times10^{25}$ yr at 90% C.L. At thisconference, we showed the decomposition of the CUORE background and were ableto extract a $^{130}$Te $2u\beta\beta$ half-life of$T_{1/2}^{2u}=[7.9\pm0.1 \mathrm{(stat.)}\pm0.2\mathrm{(syst.)}]\times10^{20}$ yr. This is the most precise measurement ofthis half-life and is consistent with previous measurements.

Published
2018

32. The CUORE and CUORE-0 experiments at LNGS

Author

Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in August 2016 and commissioning started in fall 2016. The experiment has completed the pre-operation phase and is currently in data taking. We present here the achievements of CUORE during the commissioning phase and the limit on the 130Te half-life for the neutrinoless double beta decay that has been released after the first 3 weeks of collected data. Physics results from CUORE-0 will also be updated.

Published
2018

33. Search for neutrinoless β+ EC decay of Te 120 with CUORE-0

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V

Subjects
nucl-ex
Abstract

We have performed a search for neutrinoless β+EC decay of Te120 using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of T1/2>1.6×1021 yr at 90% credibility interval (CI). Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to T1/2>2.7×1021 yr at 90% CI.

Published
2018

34. Search for neutrinoless β+EC decay of Te120 with CUORE-0

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, nucl-ex, Nuclear and plasma physics
Abstract

We have performed a search for neutrinoless β+EC decay of Te120 using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of T1/2>1.6×1021 yr at 90% credibility interval (CI). Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to T1/2>2.7×1021 yr at 90% CI.

Published
2018

35. Study of rare nuclear processes with CUORE

Author

Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, nucl-ex, physics.ins-det, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Astronomical sciences, Nuclear and plasma physics, Particle and high energy physics
Abstract

TeO2 bolometers have been used for many years to search for neutrinoless double beta decay in 130Te. CUORE, a tonne-scale TeO2 detector array, recently published the most sensitive limit on the half-life, > 1.5 × 1025 yr, which corresponds to an upper bound of 140-400 meV on the effective Majorana mass of the neutrino. While it makes CUORE a world-leading experiment looking for neutrinoless double beta decay, it is not the only study that CUORE will contribute to in the field of nuclear and particle physics. As already done over the years with many small-scale experiments, CUORE will investigate both rare decays (such as the two-neutrino double beta decay of 130Te and the hypothesized electron capture in 123Te), and rare processes (e.g. dark matter and axion interactions). This paper describes some of the achievements of past experiments that used TeO2 bolometers, and perspectives for CUORE.

Published
2018

36. Results from the CUORE experiment

Author

Marini, L, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, and Schmidt, B

Subjects
Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Nuclear and plasma physics, Particle and high energy physics
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment operated at about 10 mK reaching the ton-scale. CUORE main goal is the search for neutrinoless double beta decay in 130Te, while it is suitable also for other kinds of rare event searches, such as dark matter and axions. The detector is situated at Laboratori Nazionali del Gran Sasso (LNGS), Italy, and consists in an array of 988 TeO2 crystals, being both the detector and the source of the decay. Since the beginning of 2017, CUORE operations had both phases for physics data taking and campaigns of detector optimization to obtain the maximum from its potential. Here we briefly discuss one of the procedures for the optimization of the detector regarding noise reduction and report the achievements of CUORE concerning energy resolution and background in the region of interest after the first few months of data taking. Finally we conclude by examining the results from our first neutrinoless double beta decay analysis published at the beginning of 2018, which with a total TeO2 exposure of 86.3 kg·y allowed to place a lower limit on the decay half-life of T1/20ν(130Te) > 1.3 ×1025 yr (90% C.L.) .

Published
2018

37. The CUORE bolometric detector for neutrinoless double beta decay searches

Author

Cassina, L, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND

Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment reaching the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in 19 towers. The construction of the experiment and the installation of the detector was completed in August 2016. In this paper, the technical challenges of the construction, the design choices and measured performance of the electronic instrumentation are presented.

Published
2018

38. Long-term risk assessment in athletes with ventricular arrhythmias: the key roles of arrhythmia morphology, complexity, and substrate

Author

Compagnucci, P, primary, Casella, M, additional, Narducci, M L, additional, Conte, E, additional, Cammarano, M, additional, Pelargonio, G, additional, Andreini, D, additional, Palmieri, V, additional, Lo Russo, G, additional, Pontone, G, additional, Natale, A, additional, Tondo, C, additional, Crea, F, additional, Zeppilli, P, additional, and Dello Russo, A, additional

Published
2024
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39. The CUORE and CUORE-0 experiments at LNGS

Author

D'Addabbo, A., Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppe, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is a 1-ton scale bolometric experiment devoted to the search of the neutrinoless double-beta decay (0{\nu}\b{eta}\b{eta}) in 130Te. The CUORE detector consists of an array of 988 TeO2 crystals operated at 10 mK. CUORE-0 is the CUORE demonstrator: it has been built to test the performance of the upcoming CUORE experiment and represents the largest 130Te bolometric setup ever operated. CUORE-0 has been running at Laboratori Nazionali del Gran Sasso (Italy) from 2013 to 2015. The final CUORE-0 analysis on 0{\nu}\b{eta}\b{eta} and the corresponding detector performance are presented. The present status of the CUORE experiment, now in its final construction and commissioning phase, are discussed. The results from assembly of the detector and the commissioning of the cryostat are reported., Comment: 10 pages, 7 figures, ICNFP2016 Proceeding

Published
2016
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40. Measurement of the Two-Neutrino Double Beta Decay Half-life of $^{130}$Te with the CUORE-0 Experiment

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment
Abstract

We report on the measurement of the two-neutrino double beta decay half-life of $^{130}$Te with the CUORE-0 detector. From an exposure of 33.4 kg$\cdot$y of TeO$_2$, the half-life is determined to be $T_{1/2}^{2\nu}$ = [8.2 $\pm$ 0.2 (stat.) $\pm$ 0.6 (syst.)] $\times$ 10$^{20}$y. This result is obtained after a detailed reconstruction of the sources responsible for the CUORE-0 counting rate, with a specific study of those contributing to the $^{130}$Te neutrinoless double beta decay region of interest., Comment: Corrected typo in section 9: 3.43E5 Bq/kg should have read 3.43E-5 Bq/kg

Published
2016
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41. First array of enriched Zn$^{82}$Se bolometers to search for double beta decay

Author

Artusa, D. R., Balzoni, A., Beeman, J. W., Bellini, F., Biassoni, M., Brofferio, C., Camacho, A., Capelli, S., Cardani, L., Carniti, P., Casali, N., Cassina, L., Clemenza, M., Cremonesi, O., Cruciani, A., D'Addabbo, A., Dafinei, I., Di Domizio, S., di Vacri, M. L., Ferroni, F., Gironi, L., Giuliani, A., Gotti, C., Keppel, G., Maino, M., Mancuso, M., Martinez, M., Morganti, S., Nagorny, S., Nastasi, M., Nisi, S., Nones, C., Orio, F., Orlandi, D., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rusconi, C., Schaeffner, K., Tomei, C., Vignati, M., and Zolotarova, A.

Subjects
Physics - Instrumentation and Detectors, Physics - Atomic Physics
Abstract

The R&D activity performed during the last years proved the potential of ZnSe scintillating bolometers to the search for neutrino-less double beta decay, motivating the realization of the first large-mass experiment based on this technology: CUPID-0. The isotopic enrichment in $^{82}$Se, the Zn$^{82}$Se crystals growth, as well as the light detectors production have been accomplished, and the experiment is now in construction at Laboratori Nazionali del Gran Sasso (Italy). In this paper we present the results obtained testing the first three Zn$^{82}$Se crystals operated as scintillating bolometers, and we prove that their performance in terms of energy resolution, background rejection capability and intrinsic radio-purity complies with the requirements of CUPID-0.

Published
2016
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42. CUORE-0 detector: design, construction and operation

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Balata, M., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Brofferio, C., Buccheri, A., Bucci, C., Bulfon, C., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Carbone, L., Cardani, L., Cariello, M., Carniti, P., Casali, N., Cassina, L., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., DiPaolo, L., Drobizhev, A., Erme, G., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Freedman, S. J., Fujikawa, B. K., Gaigher, R., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Guetti, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Iannone, M., Ioannucci, L., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mazza, R., Mei, Y., Meijer, S., Michinelli, R., Miller, D., Moggi, N., Morganti, S., Mosteiro, P. J., Nastasi, M., Nisi, S., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pancaldi, G., Pattavina, L., Pavan, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Stivanello, F., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wallig, J., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment, J.2
Abstract

The CUORE experiment will search for neutrinoless double-beta decay of $^{130}$Te with an array of 988 TeO$_2$ bolometers arranged in 19 towers. CUORE-0, the first tower assembled according to the CUORE procedures, was built and commissioned at Laboratori Nazionali del Gran Sasso, and took data from March 2013 to March 2015. In this paper we describe the design, construction and operation of the CUORE-0 experiment, with an emphasis on the improvements made over a predecessor experiment, Cuoricino. In particular, we demonstrate with CUORE-0 data that the design goals of CUORE are within reach., Comment: 39 pages, 26 figures

Published
2016
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43. Analysis Techniques for the Evaluation of the Neutrinoless Double-Beta Decay Lifetime in $^{130}$Te with CUORE-0

Author

CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., Dafinei, I., Dally, A., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

We describe in detail the methods used to obtain the lower bound on the lifetime of neutrinoless double-beta ($0\nu\beta\beta$) decay in $^{130}$Te and the associated limit on the effective Majorana mass of the neutrino using the CUORE-0 detector. CUORE-0 is a bolometric detector array located at the Laboratori Nazionali del Gran Sasso that was designed to validate the background reduction techniques developed for CUORE, a next-generation experiment scheduled to come online in 2016. CUORE-0 is also a competitive $0\nu\beta\beta$ decay search in its own right and functions as a platform to further develop the analysis tools and procedures to be used in CUORE. These include data collection, event selection and processing, as well as an evaluation of signal efficiency. In particular, we describe the amplitude evaluation, thermal gain stabilization, energy calibration methods, and the analysis event selection used to create our final $0\nu\beta\beta$ decay search spectrum. We define our high level analysis procedures, with emphasis on the new insights gained and challenges encountered. We outline in detail our fitting methods near the hypothesized $0\nu\beta\beta$ decay peak and catalog the main sources of systematic uncertainty. Finally, we derive the $0\nu\beta\beta$ decay half-life limits previously reported for CUORE-0, $T^{0\nu}_{1/2}>2.7\times10^{24}$ yr, and in combination with the Cuoricino limit, $T^{0\nu}_{1/2}>4.0\times10^{24}$ yr., Comment: 18 pages, 18 figures. (Version 3 reflects only minor changes to the text. Few additional details, no major content changes.)

Published
2016
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44. The CUORE and CUORE-0 experiments at LNGS

Author

D'Addabbo, A, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is a 1-ton scale bolometric experiment devoted to the search of the neutrinoless double-beta decay (0νββ) in 130Te. The CUORE detector consists of an array of 988 TeO2 crystals operated at 10 mK. CUORE-0 is the CUORE demonstrator: it has been built to test the performance of the upcoming CUORE experiment and represents the largest 130Te bolometric setup ever operated. CUORE-0 has been running at Laboratori Nazionali del Gran Sasso (Italy) from 2013 to 2015. The final CUORE-0 analysis on 0νββ and the corresponding detector performance are presented. The present status of the CUORE experiment, now in its final construction and commissioning phase, are discussed. The results from assembly of the detector and the commissioning of the cryostat are reported.

Published
2017

45. Low energy analysis techniques for CUORE

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, and Sangiorgio, S

Subjects
physics.ins-det, nucl-ex, Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of 130Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below 60keV. Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils inCUORE-0.

Published
2017

46. Results from CUORE and CUORE-0

Author

Moggi, N, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and the installation of all towers in the cryostat was completed in August 2016: the experiment is now in data taking phase. In this talk, beyond updating the physics results from CUORE-0, we will discuss the achievements and technical challenges of the CUORE construction phase, with particular emphasis on the background reduction strategy, the performance of the detector during pre-operation and the projected first results from the full detector run.

Published
2017

47. Lowering the CUORE energy threshold

Author

Copello, S, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, CC, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is a ton-scale double beta decay experiment based on TeO2 cryogenic bolometers and is currently in the last construction stage at the Gran Sasso National Laboratory (LNGS). Its primary goal is to observe neutrino-less double beta decay of 130Te, however thanks to the ultra-low background and large projected exposure it could also be suitable for other rare event searches, as the detection of solar axions, neutrinos from type II supernovae or direct detection of dark matter. The sensitivity for these searches will depend on the performance achieved at the low energy threshold. For this reason a trigger algorithm based on continuous data filtering has been developed which will allow lowering the threshold down to the few keV region. The new trigger has been tested in CUORE-0, a single-tower CUORE prototype consisting of 52 TeO2 bolometers and recently concluded, and here we present the results in terms of trigger efficiency, data selection and low-energy calibration.

Published
2017

48. Status and prospects for CUORE

Author

Canonica, L, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Liu, X, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pirro, S, Pozzi, S, Previtali, E, and Rosenfeld, C

Subjects
Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract

CUORE is a cryogenic detector consisting of 988 TeO2 crystals, 750 g each, and will be operated at a temperature of ∼10 mK, to search for neutrinoless double beta decay (0νββ) of 130Te. The detector, in the final stages of construction at the Laboratori Nazionali del Gran Sasso (Italy), will start its operations in 2016. CUORE-0, its pilot experiment, has proven the feasibility of CUORE, demonstrating that the target background of 0.01 counts/keV/kg/y and the energy resolution of 5 keV are within reach. CUORE-0 also made the most precise measurement of the 2νββ decay. The expected sensitivity of CUORE to the 0νββ 130Te half-life is 9 •1025y, for 5 years of data taking. Here, we report the most recent results of CUORE-0, their implications for CUORE, and the current status of the CUORE experiment.

Published
2017

49. The projected background for the CUORE experiment

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, and Previtali, E

Subjects
physics.ins-det, Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of 130Te with an array of 988 TeO2 bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90% C.L. exclusion sensitivity on the 130Te decay half-life of 9 × 1025 years after 5 years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10- 2 counts/keV/kg/year. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of 130Te is expected.

Published
2017

50. CUORE sensitivity to 0 decay

Author

Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Banks, TI, Bari, G, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, and Previtali, E

Subjects
physics.ins-det, nucl-ex, Prevention, Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract

We report a study of the CUORE sensitivity to neutrinoless double beta (0) decay. We used a Bayesian analysis based on a toy Monte Carlo (MC) approach to extract the exclusion sensitivity to the 0 decay half-life (T1/20ν) at 90 % credibility interval (CI) – i.e. the interval containing the true value of T1/20ν with 90 % probability – and the 3σ discovery sensitivity. We consider various background levels and energy resolutions, and describe the influence of the data division in subsets with different background levels. If the background level and the energy resolution meet the expectation, CUORE will reach a 90 % CI exclusion sensitivity of 2 · 10 25 year with 3 months, and 9 · 10 25 year with 5 years of live time. Under the same conditions, the discovery sensitivity after 3 months and 5 years will be 7 · 10 24 year and 4 · 10 25 year, respectively.

Published
2017

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