192 results on '"Palomar-García A"'
Search Results
2. Establishment of a reproducible and minimally invasive ischemic stroke model in swine
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Carlos Castaño, Marc Melià-Sorolla, Alexia García-Serran, Núria DeGregorio-Rocasolano, Maria Rosa García-Sort, María Hernandez-Pérez, Adrián Valls-Carbó, Osvaldo Pino, Jordi Grífols, Alba Iruela-Sánchez, Alicia Palomar-García, Josep Puig, Octavi Martí-Sistac, Antoni Dávalos, and Teresa Gasull
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Neuroscience ,Medicine - Abstract
The need for advances in the management/treatment options for ischemic stroke patients requires that upcoming preclinical research uses animals with more human-like brain characteristics. The porcine brain is considered appropriate, although the presence of the rete mirabile (RM) prevents direct catheterization of the intracranial arteries to produce focal cerebral ischemia. To develop a reproducible minimally invasive porcine stroke model, a guide catheter and guide wire were introduced through the femoral artery until reaching the left RM. Using the pressure cooker technique, Squid-12 embolization material was deposited to fill, overflow, and occlude the left RM, the left internal carotid artery, and left circle of Willis wing up to the origins of the middle cerebral arteries (MCAs), mimicking the occlusion produced in the filament model in rodents. Longitudinal multimodal cerebral MRI was conducted to assess the brain damage and cerebral blood supply. The technique we describe here occluded up to the origins of the MCAs in 7 of 8 swine, inducing early damage 90 minutes after occlusion that later evolved to a large cerebral infarction and producing no mortality during the intervention. This minimally invasive ischemic stroke model in swine produced reproducible infarcts and shows translational features common to human stroke.
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- 2023
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3. Sustained and transient gray matter volume changes after n-back training: A VBM study
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Miró-Padilla, Anna, Bueichekú, Elisenda, Adrián-Ventura, Jesús, Costumero, Víctor, Palomar-García, María-Ángeles, Villar-Rodríguez, Esteban, Marin-Marin, Lidón, Aguirre, Naiara, and Ávila, César
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- 2021
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4. Bilingualism's Effects on Resting-State Functional Connectivity in Mild Cognitive Impairment.
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Lidón Marin-Marin, María-ángeles Palomar-García, Anna Miró-Padilla, Jesús Adrián-Ventura, Naiara Aguirre, Esteban Villar-Rodríguez, and Víctor Costumero
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- 2021
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5. The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
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Miró-Padilla, Anna, Adrián-Ventura, Jesús, Costumero, Víctor, Palomar-García, María-Ángeles, Villar-Rodríguez, Esteban, Marin-Marin, Lidón, Aguirre, Naiara, and Bueichekú, Elisenda
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- 2021
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6. Separate Contribution of Striatum Volume and Pitch Discrimination to Individual Differences in Music Reward
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Hernández, Mireia, Palomar-García, María-Ángeles, Nohales-Nieto, Benito, Olcina-Sempere, Gustau, Villar-Rodríguez, Esteban, Pastor, Raúl, Ávila, César, and Parcet, Maria-Antònia
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- 2019
7. The manifestation of individual differences in sensitivity to punishment during resting state is modulated by eye state
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Costumero, Víctor, Adrián-Ventura, Jesús, Bueichekú, Elisenda, Miró-Padilla, Anna, Palomar-García, María-Ángeles, Marin-Marin, Lidón, Villar-Rodríguez, Esteban, Aguirre, Naiara, Barrós-Loscertales, Alfonso, and Ávila, César
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- 2021
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8. Laboratorio en abierto: aPrendendiendo a CopiaR ADN. 3.0.
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Linacero De La Fuente, M. Rosario, Gorfinkiel Haim, Nicole, Peña Gómez, Alicia De La, Hórreo Escandón, José Luis, Espino Nuño, Francisco Javier, Muñoz Colmenero, Ana Marta, Cuñado Rodríguez, Nieves, Fernández Jiménez, Nadia, Benito Jiménez, César, González Sánchez, Mónica, Rosato, Carmen Luisa Marcela, Ballesteros Redondo, María Isabel, Méndez Cea, Belén, Gil Dones, Félix, Pradillo Orellana, Mónica, García García, Isabel, Arana Montes, María Del Pilar De, Gallego Rodríguez, Francisco Javier, Figueiras Merino, Ana Margarita, Palomar García, Gemma, Perdiguero Jiménez, Pedro, BARRIOS DIAZ, JOSE, LLANOS SAAVEDRA, CAROLINA, MORENO ORTIZ, CARMEN, Codes Valcarce, Rocío, Linacero De La Fuente, M. Rosario, Gorfinkiel Haim, Nicole, Peña Gómez, Alicia De La, Hórreo Escandón, José Luis, Espino Nuño, Francisco Javier, Muñoz Colmenero, Ana Marta, Cuñado Rodríguez, Nieves, Fernández Jiménez, Nadia, Benito Jiménez, César, González Sánchez, Mónica, Rosato, Carmen Luisa Marcela, Ballesteros Redondo, María Isabel, Méndez Cea, Belén, Gil Dones, Félix, Pradillo Orellana, Mónica, García García, Isabel, Arana Montes, María Del Pilar De, Gallego Rodríguez, Francisco Javier, Figueiras Merino, Ana Margarita, Palomar García, Gemma, Perdiguero Jiménez, Pedro, BARRIOS DIAZ, JOSE, LLANOS SAAVEDRA, CAROLINA, MORENO ORTIZ, CARMEN, and Codes Valcarce, Rocío
- Abstract
Se pretende transmitir a los estudiantes que la ciencia resuelve necesidades sociales. El punto de partida será plantear diferentes retos y situaciones que, mediante un aprendizaje activo, se pueden resolver utilizando recursos científicos.
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- 2024
9. Comparative High-Density Linkage Mapping Reveals Conserved Genome Structure but Variation in Levels of Heterochiasmy and Location of Recombination Cold Spots in the Common Frog
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Palomar García, Gemma, Ahmad, Freed, Vasemagi, Anti, Matsuba, Chikako, Nicieza, Alfredo, Cano, Jose Manuel, Palomar García, Gemma, Ahmad, Freed, Vasemagi, Anti, Matsuba, Chikako, Nicieza, Alfredo, and Cano, Jose Manuel
- Abstract
Funding Nuestra investigación contó con el apoyo de las siguientes subvenciones: Ministerio de Educación de España (referencia CGL2011-23443), Ministerio de Economía y Competitividad (referencia BES-2012-055220), Agencia Autónoma de Parques Nacionales (referencia MARM 428/211), Ministerio de Educación de Estonia e Investigación (proyecto de financiación de investigación institucional IUT8-2) y la Academia de Finlandia (subvención n.º 266321)., By combining 7077 SNPs and 61 microsatellites, we present the first linkage map for some of the early diverged lineages of the common frog, Rana temporaria, and the densest linkage map to date for this species. We found high homology with the published linkage maps of the Eastern and Western lineages but with differences in the order of some markers. Homology was also strong with the genome of the Tibetan frog Nanorana parkeri and we found high synteny with the clawed frog Xenopus tropicalis. We confirmed marked heterochiasmy between sexes and detected nonrecombining regions in several groups of the male linkage map. Contrary to the expectations set by the male heterogamety of the common frog, we did not find male heterozygosity excess in the chromosome previously shown to be linked to sex determination. Finally, we found blocks of loci showing strong transmission ratio distortion. These distorted genomic regions might be related to genetic incompatibilities between the parental populations, and are promising candidates for further investigation into the genetic basis of speciation and adaptation in the common frog., Ministerio de Economía, Industria y Competitividad (MINECO), Ministerio de Educación y Ciencia (MEC), Agencia Autónoma de Parques Nacionales, Estonian Ministry of Education and Research, Academy of Finland, Depto. de Genética, Fisiología y Microbiología, Fac. de Ciencias Biológicas, TRUE, pub
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- 2024
10. Auditory and frontal anatomic correlates of pitch discrimination in musicians, non-musicians, and children without musical training
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Palomar-García, María-Ángeles, Hernández, Mireia, Olcina, Gustau, Adrián-Ventura, Jesús, Costumero, Víctor, Miró-Padilla, Anna, Villar-Rodríguez, Esteban, and Ávila, César
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- 2020
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11. El test Jake Mandell como instrumento para medir las diferencias individuales en la discriminacion tonal: propiedades de validez y fiabilidad
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Palomar-García, María-Ángeles, Olcina-Sempere, Gustau, Hernández, Mireia, Parcet, María-Antonia, Mandell, Jacob C., and Ávila, César
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- 2020
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12. The dynamic imprint of word learning on the dorsal language pathway
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Palomar-García, María-Ángeles, Sanjuán, Ana, Bueichekú, Elisenda, Ventura-Campos, Noelia, and Ávila, César
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- 2017
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13. Functional connectivity in resting state as a phonemic fluency ability measure
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Miró-Padilla, Anna, Bueichekú, Elisenda, Ventura-Campos, Noelia, Palomar-García, María-Ángeles, and Ávila, César
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- 2017
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14. Reduced posterior parietal cortex activation after training on a visual search task
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Bueichekú, Elisenda, Miró-Padilla, Anna, Palomar-García, María-Ángeles, Ventura-Campos, Noelia, Parcet, María-Antonia, Barrós-Loscertales, Alfonso, and Ávila, César
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- 2016
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15. Adecuación de una nave para gestión de pedidos online mediante automatizaciones
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Universitat Politècnica de Catalunya. Departament d’Enginyeria Gràfica i de Disseny, Festina Lotus, Time road, Serra Casals, Jordi, Ramos Cabal, Alba, Palomar García, José Antonio, Universitat Politècnica de Catalunya. Departament d’Enginyeria Gràfica i de Disseny, Festina Lotus, Time road, Serra Casals, Jordi, Ramos Cabal, Alba, and Palomar García, José Antonio
- Abstract
Este proyecto forma parte del Trabajo de Fin de Estudios de Ingeniería en Tecnologías Industriales. Se trata de un proyecto realizado en la empresa Festina Lotus y en otras empresas/edificios del Grupo Festina. Nace de la necesidad de cambiar la gestión de pedidos online del Grupo Festina, mediante la instalación de automatizaciones y la adecuación total de una antigua nave, ubicada en Sant Just Desvern, justo enfrente del centro logístico ya existente del Grupo, TIME LOGISTIC. Inicialmente, se hizo una presentación de las debilidades del sistema de gestión previo a miembros de la dirección de la empresa, definiendo también los principales objetivos de este proyecto, para subsanar satisfactoriamente las debilidades expuestas. Se instalarán cuatro carruseles horizontales para la gestión de hasta 6.000 referencias, junto con una mesa multipedidos y cintas transportadoras. Una gran parte del proyecto consistió en la adecuación de la nave, llevando a cabo un proyecto de obras en el que, aparte de arreglar los problemas/desperfectos encontrados a la hora de adquirir la nave, surgieron nuevos problemas, como la necesidad de impermeabilizar de nuevo la cubierta de la nave y de realizar un estudio de solidez del forjado de la primera planta, entre otros. Otro punto destacable es que se llevó a cabo la instalación de energías renovables. En este caso, energía solar. Además, se llevó a cabo otro proyecto de instalaciones en referencia a clima, seguridad, montacargas y prevención contra incendios. Tal y como se presentará a lo largo de este documento, se ha concluido el proyecto consiguiendo los objetivos definidos e incluso incorporando nuevas medidas para aumentar la calidad del servicio de venta online del Grupo Festina, Aquest projecte forma part del Treball de Fi d'Estudis d'Enginyeria en Tecnologies Industrials. Es tracta d'un projecte realitzat en l'empresa Festina Lotus i en altres empreses/edificis del Grupo Festina. Neix de la necessitat de canviar la gestió de comandes en línia del Grup Festina, mitjançant la instal·lació d'automatitzacions i l'adequació total d'una antiga nau, situada a Sant Just Desvern, just enfront del centre logístic ja existent del Grup, TIME LOGISTIC. Inicialment, es va fer una presentació de les debilitats del sistema de gestió previ a membres de la direcció de l'empresa, definint també els principals objectius d'aquest projecte, per a esmenar satisfactòriament les febleses exposades. S'instal·laran quatre carrusels horitzontals per a la gestió de fins a 6.000 referències, juntament amb una taula multicomandes i cintes transportadores. Una gran part del projecte va consistir en l'adequació de la nau, duent a terme un projecte d'obres en el qual, a part d'arreglar els problemes/desperfectes trobats a l'hora d'adquirir la nau, van sorgir nous problemes, com la necessitat d'impermeabilitzar de nou la coberta de la nau i de realitzar un estudi de solidesa del forjat de la primera planta, entre altres. Un altre punt destacable és que es va dur a terme la instal·lació d'energies renovables. En aquest cas, energia solar. A més, es va dur a terme un altre projecte d'instal·lacions en referència a clima, seguretat, muntacàrregues i prevenció contra incendis. Tal com es presentarà al llarg d'aquest document, s'ha conclòs el projecte aconseguint els objectius definits i fins i tot incorporant noves mesures per a augmentar la qualitat del servei de venda en línia del Grupo Festina, This project is part of the Final Project of the Industrial Technologies Engineering Degree. It is a project carried out in the company Festina Lotus and in other companies/buildings of the Festina Group. It arises from the need to change the online order management of the Festina Group, through the installation of automation and the total adaptation of an old warehouse, located in Sant Just Desvern, just opposite the Group's existing logistics centre, TIME LOGISTIC. Initially, a presentation of the weaknesses of the previous management system was given to members of the company's management, defining also the main objectives of this project, in order to satisfactorily overcome the exposed weaknesses. Four horizontal carousels will be installed for the management of up to 6,000 references, together with a multi-column table and conveyor belts. A large part of the project consisted of the adaptation of the building, carrying out a project of works in which, apart from fixing the problems/defects found when the building was acquired, new problems arose, such as the need to re-waterproof the roof of the building and to carry out a study of the solidity of the first floor slab, among others. Another noteworthy point is that the installation of renewable energies was carried out. In this case, solar energy. In addition, another installation project was carried out in relation to climate, security, fire prevention and fire safety. As will be presented throughout this document, the project has been completed, achieving the defined objectives and even incorporating new measures to increase the quality of the online sales service of the Festina Group
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- 2023
16. Establishment of a reproducible and minimally invasive ischemic stroke model in swine
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Castaño, Carlos, primary, Melià-Sorolla, Marc, additional, García-Serran, Alexia, additional, DeGregorio-Rocasolano, Núria, additional, García-Sort, Maria Rosa, additional, Hernandez-Pérez, María, additional, Valls-Carbó, Adrián, additional, Pino, Osvaldo, additional, Grífols, Jordi, additional, Iruela-Sánchez, Alba, additional, Palomar-García, Alicia, additional, Puig, Josep, additional, Martí-Sistac, Octavi, additional, Dávalos, Antoni, additional, and Gasull, Teresa, additional
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- 2023
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17. Do bilinguals show neural differences with monolinguals when processing their native language?
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Palomar-García, María-Ángeles, Bueichekú, Elisenda, Ávila, César, Sanjuán, Ana, Strijkers, Kristof, Ventura-Campos, Noelia, and Costa, Albert
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- 2015
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18. Correction to: Auditory and frontal anatomic correlates of pitch discrimination in musicians, non‑musicians, and children without musical training
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Palomar-García, María-Ángeles, Hernández, Mireia, Olcina, Gustau, Adrián-Ventura, Jesús, Costumero, Víctor, Miró-Padilla, Anna, Villar-Rodríguez, Esteban, and Ávila, César
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- 2020
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19. Two different brain networks underlying picture naming with familiar pre-existing native words and new vocabulary
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María-Ángeles Palomar-García, Esteban Villar-Rodríguez, Cristina Pérez-Lozano, Ana Sanjuán, Elisenda Bueichekú, Anna Miró-Padilla, Victor Costumero, Jesús Adrián-Ventura, María-Antonia Parcet, and César Ávila
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Speech and Hearing ,Linguistics and Language ,Cognitive Neuroscience ,Experimental and Cognitive Psychology ,Language and Linguistics - Abstract
The present research used fMRI to longitudinally investigate the impact of learning new vocabulary on the activation pattern of the language control network by measuring BOLD signal changes during picture naming tasks with familiar pre-existing native words (old words) and new vocabulary. Nineteen healthy participants successfully learned new synonyms for already known Spanish words, and they performed a picture naming task using the old words and the new words immediately after learning and two weeks after learning. The results showed that naming with old words, compared to naming with newly learned words, produced activations in a cortical network involving frontal and parietal regions, whereas the opposite contrast showed activation in a broader cortical/subcortical network, including the SMA/ACC, the hippocampus, and the midbrain. These two networks are maintained two weeks after learning. These results suggest that the language control network can be separated into two functional circuits for diverse cognitive purposes.
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- 2023
20. Functional Connectivity Between Superior Parietal Lobule and Primary Visual Cortex 'at Rest' Predicts Visual Search Efficiency.
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Elisenda Bueichekú, Noelia Ventura-Campos, María-ángeles Palomar-García, Anna Miró-Padilla, María Antonia Parcet, and César ávila
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- 2015
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21. Efecto de la aplicación de cenizas de caldera de biomasa sobre las propiedades del suelo y el crecimiento de cultivos
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Palomar García, Patricia, Lafuente Álvarez, Francisco, Martín Sanz, Ruth Cristina, Palomar García, Patricia, Lafuente Álvarez, Francisco, and Martín Sanz, Ruth Cristina
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La combustión de biomasa agrícola y forestal constituye una fuente de energía en pleno crecimiento por ser un recurso más sostenible y económico frente a otros combustibles. Como resultado de esta combustión se obtienen cenizas que a día de hoy, son consideradas residuo cuyo ciclo de vida se cierra destinándose a vertedero. Para reducir su deposición final, se pretende revalorizar a subproducto, promoviendo la economía circular mediante su aplicación como fertilizante en el sector agrícola. Su aplicación en los suelos viene dada por ser consideradas residuo No peligroso, al no contener metales pesados por provenir de masas vegetales, por contener minerales que aportan nutrientes principalmente K, Ca, P y Mg y otros elementos como óxidos que al reaccionar con agua se transforman en hidróxidos de carácter alcalino, elevando el pH. La presente investigación se dirigió a gestionar este residuo mediante su aplicación como enmienda en 2 suelos ácidos con diferentes textura, franco-arcillosa y arenosa, observandose sus efectos en el pH y capacidad de retención de humedad y en la germinación y crecimiento de cultivos de Lactuca sativa (lechuga) y Tritucum aestivum (trigo). La experiencia se desarrolló en un invernadero de la Escuela Técnica Superior de Ingenierías Agrarias de Palencia donde se realizaron cuatro tipos de tratamientos para ambos suelos, calculados para provocar un aumento moderado de pH, tres dosis de cenizas (1, 2 y 3% en el suelo franco-arcilloso y 0,1, 0,2 y 0,3% en el arenoso) comparándose con el efecto alcalino provocado por el hidróxido de calcio. Tras el ensayo, se obtuvo una respuesta proporcional del crecimiento de los cultivos frente al aumento de dosis de ceniza, provocado por el incremento del pH de los suelos y el aporte de nutrientes. Por ello, es de gran utilidad el uso de esta enmienda como abono ya que corrige las deficiencias del suelo ante la degradación y se evita la generación de residuos., The combustion of agricultural and forestry biomass constitutes a full source of energy as it is more sustainable and economical resource than other fuels. Ashes have been obtained as a result of this combustion; nowadays these ashes are considered a waste whose life cycle is closed and sent to landfill. To reduce its final deposition, it is intended to revalue a by-product, promoting the circular economy through its application as a fertilizer in the agricultural sector. Its application in soils is given by being considered non-hazardous waste, as it does not contain heavy metals for the reason that it comes from plant masses and because it contains minerals that provide nutrients as mainly K, Ca, P and Mg and other elements such as oxides that when they react with water, these oxides are transformed into alkaline hydroxides, raising, in this way, the pH. The present investigation is aimed at managing this residue through its application as an amendment in 2 acid soils with different textures, clay-loam and sandy soils, observing its effects on the pH and its moisture retention capacity and on the germination and growth of Lactuca sativa (lettuce) and Tritucum aestivum (wheat). The experience was developed in a greenhouse of the Higher Technical School of Agricultural Engineering of Palencia where four types of treatments were carried out for both soils, calculated to cause a moderate increase in pH, three doses of ashes (1, 2 and 3% in the clay-loam soil and 0.1, 0.2 and 0.3% in the sandy soil) compared with the alkaline effect caused by calcium hydroxide. After the test, a proportional response was obtained in the growth of the crops against the increase in the dose of ash, caused by the increase in the pH of the soils and by the contribution of nutrients. For this reason, the use of this amendment as a fertilizer is very useful since it corrects the deficiencies of the soil in the face of degradation and it also avoids the creation of waste, Departamento de Ciencias Agroforestales, Máster en Ingeniería Ambiental
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- 2022
22. Significación clínica de la asimetría amigdalina
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Tobias Gómez, Susanna, Palomar Asenjo, Víctor, Borràs Perera, Montserrat, Pérez Hernández, Isabel, Ruiz Giner, Antonio, and Palomar García, Víctor
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- 2009
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23. Clinical significance of unilateral tonsillar enlargement
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Tobias Gómez, Susanna, Palomar Asenjo, Víctor, Borràs Perera, Montserrat, Pérez Hernández, Isabel, Ruiz Giner, Antonio, and Palomar García, Víctor
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- 2009
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24. Distance disintegration characterizes node-level topological dysfunctions in cocaine addiction
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Juan Carlos Bustamante, Alfonso Barrós-Loscertales, Anna Miró-Padilla, Víctor Costumero, María-Ángeles Palomar-García, Juan José Llopis, Patricia Rosell Negre, Jesús Adrián-Ventura, Paola Fuentes-Claramonte, and Jorge Sepulcre
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Adult ,Male ,media_common.quotation_subject ,graph theory ,Medicine (miscellaneous) ,cocaine ,Topology ,03 medical and health sciences ,Cocaine-Related Disorders ,0302 clinical medicine ,medicine ,Image Processing, Computer-Assisted ,Humans ,resting state ,Clustering coefficient ,media_common ,Pharmacology ,Temporal cortex ,Brain Mapping ,Resting state fMRI ,Addiction ,Ventral striatum ,functional connectivity ,Patient Acuity ,Brain ,Cognition ,Middle Aged ,Magnetic Resonance Imaging ,030227 psychiatry ,Psychiatry and Mental health ,medicine.anatomical_structure ,Connectome ,addiction ,Psychology ,Insula ,030217 neurology & neurosurgery ,optimal connectivity distance - Abstract
Previous investigations have used global graph theory measures in order to disentangle the complexity of the neural reorganizations occurring in cocaine use disorder (CUD). However, how these global topological alterations map into individual brain network areas remains unknown. In this study, we used resting state functional magnetic resonance imaging (fMRI) data to investigate node-level topological dysfunctions in CUD. The sample was composed of 32 individuals with CUD and 32 healthy controls, matched in age, years of education and intellectual functioning. Graph theory measures of optimal connectivity distance, node strength, nodal efficiency and clustering coefficient were estimated in each participant using voxel-wise functional connectivity connectomes. CUD individuals as compared with healthy controls showed higher optimal connectivity distances in ventral striatum, insula, cerebellum, temporal cortex, lateral orbitofrontal cortex, middle frontal cortex and left hippocampus. Furthermore, clinical measures quantifying severity of dependence were positively related with optimal connectivity distances in the right rolandic operculum and the right lateral orbitofrontal cortex, whereas length of abstinence was negatively associated with optimal connectivity distances in the right temporal pole and the left insula. Our results reveal a topological distancing of cognitive and affective related areas in addiction, suggesting an overall reduction in the communication capacity of these regions. Funding for open access charge: CRUE-Universitat Jaume I This research was supported by grant 040/2011 from Spanish National Drug Strategy, Ministerio de Sanidad y Consumo to ABL. JAV was supported by a predoctoral graduate programme grant (National FPU). MPG and AMP were supported by a postdoctoral graduate programme grant (postdoc-UJI). VC was supported by grant PID2019-105077RJ-I00 from Ministerio de Ciencia, Innovación y Universidades.
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- 2021
25. Fístula faringocutánea tras laringectomía total. Estudio de casos y controles de los factores de riesgo implicados en su aparición
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Palomar-Asenjo, Víctor, Sarroca Capell, Esteban, Tobías Gómez, Susanna, Pérez Hernández, Isabel, and Palomar-García, Víctor
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- 2008
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26. Distance disintegration characterizes node-level topological dysfunctions in cocaine addiction.
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Costumero, Víctor, Rosell Negre, Patricia, Bustamante, Juan Carlos, Fuentes‐Claramonte, Paola, Adrián‐Ventura, Jesús, Palomar‐García, María‐Ángeles, Miró‐Padilla, Anna, Llopis, Juan José, Sepulcre, Jorge, Barrós‐Loscertales, Alfonso, Fuentes-Claramonte, Paola, Adrián-Ventura, Jesús, Palomar-García, María-Ángeles, Miró-Padilla, Anna, and Barrós-Loscertales, Alfonso
- Subjects
LARGE-scale brain networks ,COCAINE abuse ,TEMPORAL lobe ,FRONTAL lobe ,PREFRONTAL cortex - Abstract
Previous investigations have used global graph theory measures in order to disentangle the complexity of the neural reorganizations occurring in cocaine use disorder (CUD). However, how these global topological alterations map into individual brain network areas remains unknown. In this study, we used resting state functional magnetic resonance imaging (fMRI) data to investigate node-level topological dysfunctions in CUD. The sample was composed of 32 individuals with CUD and 32 healthy controls, matched in age, years of education and intellectual functioning. Graph theory measures of optimal connectivity distance, node strength, nodal efficiency and clustering coefficient were estimated in each participant using voxel-wise functional connectivity connectomes. CUD individuals as compared with healthy controls showed higher optimal connectivity distances in ventral striatum, insula, cerebellum, temporal cortex, lateral orbitofrontal cortex, middle frontal cortex and left hippocampus. Furthermore, clinical measures quantifying severity of dependence were positively related with optimal connectivity distances in the right rolandic operculum and the right lateral orbitofrontal cortex, whereas length of abstinence was negatively associated with optimal connectivity distances in the right temporal pole and the left insula. Our results reveal a topological distancing of cognitive and affective related areas in addiction, suggesting an overall reduction in the communication capacity of these regions. [ABSTRACT FROM AUTHOR]
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- 2021
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27. Pharyngocutaneous Fistula Following Total Laryngectomy. ACase-Control Study of Risk Factors Implicated in its Onset
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Palomar-Asenjo, Víctor, Sarroca Capell, Esteban, Tobías Gómez, Susanna, Pérez Hernández, Isabel, and Palomar-García, Víctor
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- 2008
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28. HAPTIC RECOGNITION OF FAMILIAR OBJECTS: EXAMINING LATERALIZATION OF SPECIFICITY EFFECTS
- Author
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González-Alvarez, Julio and Palomar-García, María-Ángeles
- Published
- 2014
- Full Text
- View/download PDF
29. The Manifestation of individual differences in sensitivity to punishment during resting state is modulated by eye state
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César Ávila, Elisenda Bueichekú, María-Ángeles Palomar-García, Naiara Aguirre, Alfonso Barrós-Loscertales, Anna Miró-Padilla, Víctor Costumero, Lidón Marin-Marin, Esteban Villar-Rodríguez, and Jesús Adrián-Ventura
- Subjects
Punishment (psychology) ,Cognitive Neuroscience ,Hippocampus ,Anxiety ,Affect (psychology) ,Amygdala ,Periaqueductal gray ,050105 experimental psychology ,03 medical and health sciences ,Behavioral Neuroscience ,0302 clinical medicine ,Functional neuroimaging ,medicine ,0501 psychology and cognitive sciences ,Resting state ,Sensitivity to punishment ,Resting state fMRI ,05 social sciences ,Eyes open/closed ,medicine.anatomical_structure ,nervous system ,medicine.symptom ,Psychology ,Neuroscience ,psychological phenomena and processes ,030217 neurology & neurosurgery - Abstract
Structural and functional neuroimaging studies have shown that brain areas associated with fear and anxiety (defensive system areas) are modulated by individual differences in sensitivity to punishment (SP). However, little is known about how SP is related to brain functional connectivity and the factors that modulate this relationship. In this study, we investigated whether a simple methodological manipulation, such as performing a resting state with eyes open or eyes closed, can modulate the manifestation of individual differences in SP. To this end, we performed an exploratory fMRI resting state study in which a group of participants (n = 88) performed a resting state with eyes closed and another group (n = 56) performed a resting state with eyes open. All participants completed the Sensitivity to Punishment and Sensitivity to Reward Questionnaire. Seed-based functional connectivity analyses were performed in the amygdala, hippocampus, and periaqueductal gray (PAG). Our results showed that the relationship between SP and left amygdala-precuneus and left hippocampus-precuneus functional connectivity was modulated by eye state. Moreover, in the eyes open group, SP was negatively related to the functional connectivity between the PAG and amygdala and between the PAG and left hippocampus, and it was positively related to the functional connectivity between the amygdala and hippocampus. Together, our results may suggest underlying differences in the connectivity between anxiety-related areas based on eye state, which in turn would affect the manifestation of individual differences in SP. This work was supported by grants from Generalitat Valenciana (PROMETEO/2017/109) and Ministerio de Economía y Competitividad (PSI2016-78805-R) to C.A. Also, it was supported by a grant from Jaume I University (UJI-B2016-21) to A.B-L. Additionally, this work was supported by a pre-doctoral graduate program grant (National FPU to J.A-V, L.M-M, E.V-R and N.A) and a post-doctoral graduate program grant (Juan de la Cierva to V.C and postdoc-UJI to A.M-P and M-Á.P-G). Author E.B was funded by a post-doctoral grant from the "Generalitat Valenciana (2018 APOSTD)" and the "European Social Fund (Investing in your future)"
- Published
- 2021
30. The manifestation of individual differences in sensitivity to punishment during resting state is modulated by eye state
- Author
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Víctor, Costumero, Jesús, Adrián-Ventura, Elisenda, Bueichekú, Anna, Miró-Padilla, María-Ángeles, Palomar-García, Lidón, Marin-Marin, Esteban, Villar-Rodríguez, Naiara, Aguirre, Alfonso, Barrós-Loscertales, and César, Ávila
- Subjects
Punishment ,Functional Neuroimaging ,Individuality ,Brain ,Humans ,Magnetic Resonance Imaging - Abstract
Structural and functional neuroimaging studies have shown that brain areas associated with fear and anxiety (defensive system areas) are modulated by individual differences in sensitivity to punishment (SP). However, little is known about how SP is related to brain functional connectivity and the factors that modulate this relationship. In this study, we investigated whether a simple methodological manipulation, such as performing a resting state with eyes open or eyes closed, can modulate the manifestation of individual differences in SP. To this end, we performed an exploratory fMRI resting state study in which a group of participants (n = 88) performed a resting state with eyes closed and another group (n = 56) performed a resting state with eyes open. All participants completed the Sensitivity to Punishment and Sensitivity to Reward Questionnaire. Seed-based functional connectivity analyses were performed in the amygdala, hippocampus, and periaqueductal gray (PAG). Our results showed that the relationship between SP and left amygdala-precuneus and left hippocampus-precuneus functional connectivity was modulated by eye state. Moreover, in the eyes open group, SP was negatively related to the functional connectivity between the PAG and amygdala and between the PAG and left hippocampus, and it was positively related to the functional connectivity between the amygdala and hippocampus. Together, our results may suggest underlying differences in the connectivity between anxiety-related areas based on eye state, which in turn would affect the manifestation of individual differences in SP.
- Published
- 2020
31. The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
- Author
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Jesús Adrián-Ventura, Lidón Marin-Marin, Naiara Aguirre, Elisenda Bueichekú, Esteban Villar-Rodríguez, Anna Miró-Padilla, María-Ángeles Palomar-García, and Víctor Costumero
- Subjects
Adult ,Male ,medicine.medical_specialty ,Histology ,Neurology ,Thalamus ,Population ,Inferior frontal gyrus ,adhesio interthalamica ,Audiology ,Frontal cortex ,050105 experimental psychology ,Premotor cortex ,03 medical and health sciences ,0302 clinical medicine ,CAT12 ,medicine ,voxel-based morphometry ,Humans ,0501 psychology and cognitive sciences ,Gray Matter ,Gray matter ,education ,Temporal cortex ,education.field_of_study ,business.industry ,General Neuroscience ,05 social sciences ,Cognition ,Voxel-based morphometry ,Magnetic Resonance Imaging ,Temporal Lobe ,medicine.anatomical_structure ,Individual differences ,Schizophrenia ,Female ,Anatomy ,business ,030217 neurology & neurosurgery - Abstract
The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3–22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (n = 31) presented complete AI absence vs. 32.9% of participants (n = 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults.
- Published
- 2020
32. O teste de Jake Mandell como instrumento para medir diferenças individuais na discriminação de tonalidade: propiedades de validade e confibialidade
- Author
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María Antonia Parcet Ibars, María-Ángeles Palomar-García, Gustau Olcina Sempere, César Ávila, Jacob Mandell, and Mireia Hernández
- Subjects
medicine.medical_specialty ,Psychometrics ,Discriminación de tono ,brain ,Validity ,neuroimagen ,Amusia ,Audiology ,050105 experimental psychology ,Education ,habilidades musicales ,03 medical and health sciences ,Tone (musical instrument) ,Musical ability ,0302 clinical medicine ,Jake Mandell Tone Deaf Test (JMT) ,To (Fonètica) ,medicine ,0501 psychology and cognitive sciences ,Aptitud per a la música ,Tests neuropsicològics ,Reliability (statistics) ,neuroimaging ,05 social sciences ,cerebro ,medicine.disease ,Discrimination testing ,Test (assessment) ,Diagnòstic per la imatge ,Tone deafness ,Pitch Discrimination ,Test de Jake Mandell (JMT) ,Neuropsychological tests ,Diagnostic imaging ,Pitch discrimination ,Tone (Phonetics) ,Psychology ,musical abilities ,Psicometria ,030217 neurology & neurosurgery ,Music - Abstract
The Jake Mandell Tone Deaf Test (JMT) is an online measure designed to evaluate pitch discrimination in the normal population. The test has been available online since 2006, but no psychometric data have been published. The present research was designed to provide validity and reliability data for this test. Study 1 was conducted in university students, and the performance on the JMT was compared to the AMUSIA online screening tests. Correlations were high with the subtests of the AMUSIA online screening tests, but especially with the Tone discrimination test. Study 2 was conducted in children, and the JMT was compared to different tests of musical abilities. The JMT showed a good relationship with the Tone Discrimination and Rhythm Imitation subtest, but especially with the global score of musical abilities. In addition, the test showed good one-year test-retest reliability. Finally, external validation of the JMT was obtained by noting that musicians obtained higher scores than non-musicians. Discussion is focused on the possibility of using the JMTas a rapid screening measure of individual differences in pitch discrimination in the normal population. El test de Jake Mandell (JMT) es un test online diseñado para evaluar la discriminación tonal en la población normal. El test está disponible online desde 2006, pero no se han publicado datos psicométricos. La presente investigación fue diseñada para proporcionar datos de validez y fiabilidad para este test. El estudio 1 se realizó en estudiantes universitarios, y el rendimiento en el JMT se comparó con las pruebas de detección online denominadas AMUSIA. Las correlaciones fueron altas con los subtests de AMUSIA, pero especialmente con el de discriminación de tonos. El estudio 2 se realizó en niños, y el JMT se comparó con diferentes pruebas de habilidades musicales. El JMT mostró una buena relación con el subtest de discriminación de tono e imitación de ritmo, pero especialmente con la puntuación global de las habilidades musicales. Además, el test mostró una buena fiabilidad test-retest al cabo de un año. Finalmente, la validación externa del JMT se obtuvo al señalar que los músicos obtuvieron puntuaciones más altas que los no músicos. La discusión se centra en la posibilidad de utilizar el JMT como una medida de detección rápida de las diferencias individuales en la discriminación de tono en la población normal. O teste de surdez de tom de Jake Mandell (JMT) é uma medida on-line projetada para avaliar a discriminação de tom na população normal. O teste está disponível online desde 2006, mas nenhum dado psicométrico foi publicado. A presente pesquisa foi projetada para fornecer dados de validade e confiabilidade para este teste. O estudo 1 foi realizado em estudantes universitários, e o desempenho no JMT foi comparado aos testes de triagem on-line da AMUSIA. As correlações foram altas com os subtestes dos testes de triagem on-line da AMUSIA, mas principalmente com o teste de discriminação de tons. O estudo 2 foi realizado em crianças e o JMT foi comparado a diferentes testes de habilidades musicais. O JMT mostrou uma boa relação com o subteste Discriminação de Tom e Imitação de Ritmo, mas principalmente com o escore global de habilidades musicais. Além disso, o teste mostrou boa confiabilidade teste-reteste de um ano. Finalmente, a validação externa do JMT foi obtida observando que os músicos obtiveram pontuações mais altas que os não músicos. A discussão está focada na possibilidade de usar o JMT como uma medida de triagem rápida das diferenças individuais na discriminação de arremesso na população normal.  
- Published
- 2020
33. The Silent Sinus Syndrome
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Borràs Perera, Montserrat, Palomar Asenjo, Víctor, Soteras Ollé, Josep, Carles Fortuny Llanses, Joan, and Palomar García, Víctor
- Published
- 2007
- Full Text
- View/download PDF
34. The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
- Author
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Miró-Padilla, Anna, primary, Adrián-Ventura, Jesús, additional, Costumero, Víctor, additional, Palomar-García, María-Ángeles, additional, Villar-Rodríguez, Esteban, additional, Marin-Marin, Lidón, additional, Aguirre, Naiara, additional, and Bueichekú, Elisenda, additional
- Published
- 2021
- Full Text
- View/download PDF
35. Twenty-two years of psychological science in Psychological Science
- Author
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González-Alvarez, Julio and Palomar-García, M Angeles
- Published
- 2014
- Full Text
- View/download PDF
36. Bilingualism's Effects on Resting-State Functional Connectivity in Mild Cognitive Impairment
- Author
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Marin-Marin, Lidón, primary, Palomar-García, María-Ángeles, additional, Miró-Padilla, Anna, additional, Adrián-Ventura, Jesús, additional, Aguirre, Naiara, additional, Villar-Rodríguez, Esteban, additional, and Costumero, Victor, additional
- Published
- 2021
- Full Text
- View/download PDF
37. The Jake Mandell Test as a measure of individual differences in pitch discrimination: validity and reliability properties.
- Author
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Olcina Sempere, Gustau, primary, Palomar-García, María-Ángeles, additional, Hernández, Mireia, additional, Parcet Ibars, María Antonia, additional, Mandell, Jacob, additional, and Ávila, César, additional
- Published
- 2020
- Full Text
- View/download PDF
38. Left-handed musicians show a higher probability of atypical cerebral dominance for language
- Author
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Mireia Hernández, César Ávila, Gustau Olcina-Sempere, María-Ángeles Palomar-García, Maria Antònia Parcet, Jesús Adrián-Ventura, and Esteban Villar-Rodríguez
- Subjects
Male ,Dominància cerebral ,hemispheric language dominance ,Right angular gyrus ,Musicians ,Audiology ,Functional Laterality ,0302 clinical medicine ,Gyrus ,Research Articles ,Dominance (genetics) ,Language ,Temporal cortex ,Cerebral Cortex ,Radiological and Ultrasound Technology ,Functional connectivity ,05 social sciences ,musicians ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Neurology ,Hemispheric language dominance ,Female ,Anatomy ,Psychology ,Research Article ,Adult ,medicine.medical_specialty ,Auditory cortex ,Left- and right-handedness ,050105 experimental psychology ,Lateralization of brain function ,03 medical and health sciences ,Young Adult ,Lateralitat manual ,medicine ,Functional laterality ,lateralization ,Humans ,0501 psychology and cognitive sciences ,Radiology, Nuclear Medicine and imaging ,Dominance, Cerebral ,Left-handedness ,Left handed ,Lateralization ,Gramàtica cognitiva ,Músics ,Cognitive grammar ,Cerebral dominance ,Neurology (clinical) ,030217 neurology & neurosurgery ,left‐handedness ,Music - Abstract
Music processing and right hemispheric language lateralization share a common network in the right auditory cortex and its frontal connections. Given that the development of hemispheric language dominance takes place over several years, this study tested whether musicianship could increase the probability of observing right language dominance in left-handers. Using a classic fMRI language paradigm, results showed that atypical lateralization was more predominant in musicians (40%) than in nonmusicians (5%). Comparison of left-handers with typical left and atypical right lateralization revealed that: (a) atypical cases presented a thicker right pars triangularis and more gyrified left Heschl's gyrus; and (b) the right pars triangularis of atypical cases showed a stronger intra-hemispheric functional connectivity with the right angular gyrus, but a weaker interhemispheric functional connectivity with part of the left Broca's area. Thus, musicianship is the first known factor related to a higher prevalence of atypical language dominance in healthy left-handed individuals. We suggest that differences in the frontal and temporal cortex might act as shared predisposing factors to both musicianship and atypical language lateralization.
- Published
- 2020
39. Separate Contribution of Striatum Volume and Pitch Discrimination to Individual Differences in Music Reward
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Mireia Hernández, Maria-Antònia Parcet, Raúl Pastor, Gustau Olcina-Sempere, María-Ángeles Palomar-García, Esteban Villar-Rodríguez, Benito Nohales-Nieto, and César Ávila
- Subjects
Adult ,Male ,music perception ,Adolescent ,striatum ,media_common.quotation_subject ,Individuality ,Striatum ,050105 experimental psychology ,Nucleus Accumbens ,Pleasure ,Pitch Discrimination ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Reward ,voxel-based morphometry ,Humans ,0501 psychology and cognitive sciences ,individual differences ,General Psychology ,media_common ,music reward ,Functional connectivity ,05 social sciences ,Voxel-based morphometry ,Magnetic Resonance Imaging ,humanities ,Music perception ,Female ,Caudate Nucleus ,Psychology ,human activities ,psychological phenomena and processes ,030217 neurology & neurosurgery ,Music ,Cognitive psychology ,Volume (compression) - Abstract
Individual differences in the level of pleasure induced by music have been associated with the response of the striatum and differences in functional connectivity between the striatum and the auditory cortex. In this study, we tested whether individual differences in music reward are related to the structure of the striatum and the ability to discriminate pitch. We acquired a 3-D magnetization-prepared rapid-acquisition gradient-echo image for 32 musicians and 26 nonmusicians who completed a music-reward questionnaire and a test of pitch discrimination. The analysis of both groups together showed that sensitivity to music reward correlated negatively with the volume of both the caudate and nucleus accumbens and correlated positively with pitch-discrimination abilities. Moreover, musicianship, pitch discrimination, and caudate volume significantly predicted individual differences in music reward. These results are consistent with the proposal that individual differences in music reward depend on the interplay between auditory abilities and the reward network.
- Published
- 2019
40. The Jake Mandell Test as a measure of individual differences in pitch discrimination: validity and reliability properties.
- Author
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Olcina Sempere, Gustau, Palomar-García, María-Ángeles, Hernández, Mireia, Parcet Ibars, María Antonia, Mandell, Jacob, Ávila, César, Olcina Sempere, Gustau, Palomar-García, María-Ángeles, Hernández, Mireia, Parcet Ibars, María Antonia, Mandell, Jacob, and Ávila, César
- Abstract
The Jake Mandell Tone Deaf Test (JMT) is an online measure designed to evaluate pitch discrimination in the normal population. The test has been available online since 2006, but no psychometric data have been published. The present research was designed to provide validity and reliability data for this test. Study 1 was conducted in university students, and the performance on the JMT was compared to the AMUSIA online screening tests. Correlations were high with the subtests of the AMUSIA online screening tests, but especially with the Tone discrimination test. Study 2 was conducted in children, and the JMT was compared to different tests of musical abilities. The JMT showed a good relationship with the Tone Discrimination and Rhythm Imitation subtest, but especially with the global score of musical abilities. In addition, the test showed good one-year test-retest reliability. Finally, external validation of the JMT was obtained by noting that musicians obtained higher scores than non-musicians. Discussion is focused on the possibility of using the JMT as a rapid screening measure of individual differences in pitch discrimination in the normal population., El test de Jake Mandell (JMT) es un test online diseñado para evaluar la discriminación tonal en la población normal. El test está disponible online desde 2006, pero no se han publicado datos psicométricos. La presente investigación fue diseñada para proporcionar datos de validez y fiabilidad para este test. El estudio 1 se realizó en estudiantes universitarios, y el rendimiento en el JMT se comparó con las pruebas de detección online denominadas AMUSIA. Las correlaciones fueron altas con los subtests de AMUSIA, pero especialmente con el de discriminación de tonos. El estudio 2 se realizó en niños, y el JMT se comparó con diferentes pruebas de habilidades musicales. El JMT mostró una buena relación con el subtest de discriminación de tono e imitación de ritmo, pero especialmente con la puntuación global de las habilidades musicales. Además, el test mostró una buena fiabilidad test-retest al cabo de un año. Finalmente, la validación externa del JMT se obtuvo al señalar que los músicos obtuvieron puntuaciones más altas que los no músicos. La discusión se centra en la posibilidad de utilizar el JMT como una medida de detección rápida de las diferencias individuales en la discriminación de tono en la población normal., O teste de surdez de tom de Jake Mandell (JMT) é uma medida on-line projetada para avaliar a discriminação de tom na população normal. O teste está disponível online desde 2006, mas nenhum dado psicométrico foi publicado. A presente pesquisa foi projetada para fornecer dados de validade e confiabilidade para este teste. O estudo 1 foi realizado em estudantes universitários, e o desempenho no JMT foi comparado aos testes de triagem on-line da AMUSIA. As correlações foram altas com os subtestes dos testes de triagem on-line da AMUSIA, mas principalmente com o teste de discriminação de tons. O estudo 2 foi realizado em crianças e o JMT foi comparado a diferentes testes de habilidades musicais. O JMT mostrou uma boa relação com o subteste Discriminação de Tom e Imitação de Ritmo, mas principalmente com o escore global de habilidades musicais. Além disso, o teste mostrou boa confiabilidade teste-reteste de um ano. Finalmente, a validação externa do JMT foi obtida observando que os músicos obtiveram pontuações mais altas que os não músicos. A discussão está focada na possibilidade de usar o JMT como uma medida de triagem rápida das diferenças individuais na discriminação de arremesso na população normal.  
- Published
- 2020
41. Syllable Frequency and Spoken Word Recognition
- Author
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María-Ángeles Palomar-García and Julio González-Alvarez
- Subjects
Adult ,Male ,auditory lexical decision ,syllable frequency ,Speech perception ,Adolescent ,Speech recognition ,050105 experimental psychology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Stress (linguistics) ,spoken word recognition ,Lexical decision task ,Humans ,lexical frequency ,0501 psychology and cognitive sciences ,General Psychology ,Language ,inhibitory effects ,Syllable frequency ,05 social sciences ,Recognition, Psychology ,Inhibition, Psychological ,Spain ,Spoken word recognition ,Speech Perception ,Female ,Syllabic verse ,Syllable ,Psychology ,030217 neurology & neurosurgery ,Word (group theory) - Abstract
Research has shown that syllables play a relevant role in lexical access in Spanish, a shallow language with a transparent syllabic structure. Syllable frequency has been shown to have an inhibitory effect on visual word recognition in Spanish. However, no study has examined the syllable frequency effect on spoken word recognition. The present study tested the effect of the frequency of the first syllable on recognition of spoken Spanish words. A sample of 45 young adults (33 women, 12 men; M = 20.4, SD = 2.8; college students) performed an auditory lexical decision on 128 Spanish disyllabic words and 128 disyllabic nonwords. Words were selected so that lexical and first syllable frequency were manipulated in a within-subject 2 × 2 design, and six additional independent variables were controlled: token positional frequency of the second syllable, number of phonemes, position of lexical stress, number of phonological neighbors, number of phonological neighbors that have higher frequencies than the word, and acoustical durations measured in milliseconds. Decision latencies and error rates were submitted to linear mixed models analysis. Results showed a typical facilitatory effect of the lexical frequency and, importantly, an inhibitory effect of the first syllable frequency on reaction times and error rates. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors received financial support for the research and publication of this article from the University Jaume I.
- Published
- 2016
- Full Text
- View/download PDF
42. Left‐handed musicians show a higher probability of atypical cerebral dominance for language
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Villar‐Rodríguez, Esteban, primary, Palomar‐García, María‐Ángeles, additional, Hernández, Mireia, additional, Adrián‐Ventura, Jesús, additional, Olcina‐Sempere, Gustau, additional, Parcet, María‐Antònia, additional, and Ávila, César, additional
- Published
- 2020
- Full Text
- View/download PDF
43. Differential introgression across newt hybrid zones: Evidence from replicated transects
- Author
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Zielinski, Piotr, Dudek, Katarzyna, Arntzen, Jan, Palomar García, Gemma, Niedzicka, Marta, Fijarczyk, Anna, Liana, Marcin, Cogalniceanu, Dan, Babik, Wieslaw, Zielinski, Piotr, Dudek, Katarzyna, Arntzen, Jan, Palomar García, Gemma, Niedzicka, Marta, Fijarczyk, Anna, Liana, Marcin, Cogalniceanu, Dan, and Babik, Wieslaw
- Abstract
Funding El trabajo fue apoyado por la subvención no. 2014/15/B/NZ8/00250 a PZ Polish National Science Centre, y por la subvención no. DS/WB/INoS/762/2018 Jagiellonian University, Genomic heterogeneity of divergence between hybridizing species may reflect heterogeneity of introgression, but also processes unrelated to hybridization. Heterogeneous introgression and its repeatability can be directly tested in natural hybrid zones by examining multiple transects. Here, we studied hybrid zones between the European newts Lissotriton montandoni and two lineages of Lissotriton vulgaris, with replicate transects within each zone. Over 1,000 nuclear genes located on a linkage map and mitochondrial DNA were investigated using geographical and genomic clines. Overall, the five transects were all similar, showing hallmarks of strong reproductive isolation: bimodal distribution of genotypes in central populations and narrow allele frequency clines. However, the extent of introgression differed between the zones, possibly as a consequence of their different ages, as suggested by the analysis of heterozygosity runs in diagnostic markers. In three transects genomic signatures of small-scale (~2 km) zone movements were detected. We found limited overlap of cline outliers between transects, and only weak evidence of stronger differentiation of introgression between zones than between transects within zones. Introgression was heterogeneous across linkage groups, with patterns of heterogeneity similar between transects and zones. Predefined candidates for increased or reduced introgression exhibited only a subtle tendency in the expected direction, suggesting that interspecific differentiation is not a reliable indicator for the strength of introgression. These hierarchically sampled hybrid zones of apparently different ages show how introgression unfolds with time and offer an excellent opportunity to dissect the dynamics of hybridization and architecture of reproductive isolation at advanced stages of speciation., Polish National Science Centre, Jagiellonian University, Depto. de Genética, Fisiología y Microbiología, Fac. de Ciencias Biológicas, TRUE, pub
- Published
- 2019
44. Mapping of quantitative trait loci for life history traits segregating within common frog populations
- Author
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Palomar García, Gemma, Vasemagi, Anti, Ahmad, Freed, Nicieza, Alfredo, Cano, Jose Manuel, Palomar García, Gemma, Vasemagi, Anti, Ahmad, Freed, Nicieza, Alfredo, and Cano, Jose Manuel
- Abstract
Funding Esta investigación ha contado con el apoyo de las siguientes ayudas: Ministerio de Educación de España (referencias CGL2011-23443 y CGL2012-40246-C02-02), Ministerio de Economía y Competitividad (referencia BES-2012-055220), Agencia Autónoma de Parques Nacionales (OAPN) ( referencia MARM 428/211), el Ministerio de Educación e Investigación de Estonia (proyecto de financiación de investigación institucional IUT8-2) y la Academia de Finlandia (subvención n.º 266321)., The evolution of complex traits is often shaped by adaptive divergence. However, very little is known about the number, effect size, and location of the genomic regions influencing the variation of these traits in natural populations. Based on a dense linkage map of the common frog, Rana temporaria, we have localized, for the first time in amphibians, three significant and nine suggestive quantitative trait loci (QTLs) for metabolic rate, growth rate, development time, and weight at metamorphosis, explaining 5.6–18.9% of the overall phenotypic variation in each trait. We also found a potential pleiotropic QTL between development time and size at metamorphosis that, if confirmed, might underlie the previously reported genetic correlation between these traits. Furthermore, we demonstrate that the genetic variation linked to fitness-related larval traits segregates within Rana temporaria populations. This study provides the first insight into the genomic regions that affect larval life history traits in anurans, providing a valuable resource to delve further into the genomic basis of evolutionary change in amphibians., Ministerio de Economía, Industria y Competitividad (España), Ministerio de Educación y Ciencia (ESpaña), Agencia Autónoma de Parques Nacionales, Ministry of Education and Research (Estonia), Academy of Finland, Depto. de Genética, Fisiología y Microbiología, Fac. de Ciencias Biológicas, TRUE, pub
- Published
- 2019
45. Tratamiento de la patología del complejo incudomaleolar combinada con fijación del estribo mediante maleoestapedotomía
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Palomar Asenjo, V., Palomar García, V., Fortuny Llanses, J.C., and Ruiz Giner, A.
- Published
- 2001
- Full Text
- View/download PDF
46. Actividad del cidofovir en la papilomatosis respiratoria infantil recidivante
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Palomar Asenjo, V., Palomar García, V., Soteras Ollé, J., and Ruiz Giner, A.
- Published
- 2001
- Full Text
- View/download PDF
47. Modificaciones de las interacciones audio-motoras asociadas con la formación musical y el aprendizaje de un vocabulario nuevo
- Author
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Palomar García, María Ángeles, Ávila Rivera, César, Sanjuán Tomás, Ana, and Universitat Jaume I. Departament de Psicologia Bàsica, Clínica i Psicobiologia
- Subjects
Brain activation ,Vocabulary ,Estado de reposo ,Plasticidad cerebral ,First language ,media_common.quotation_subject ,Musical instrument ,159.9 ,Lenguaje ,Resting state ,Language ,media_common ,Aprendizaje ,Brain plasticity ,Communication ,business.industry ,Resonancia magnética funcional ,Functional connectivity ,Art ,Acquisition ,Psicologia ,business ,Music ,Música ,Cognitive psychology - Abstract
Esta tesis tiene como objetivo investigar los cambios cerebrales que se producen como consecuencia de la estimulación audio-motora. Para ello, se han utilizado medidas de actividad y de conectividad funcional entre las regiones cerebrales implicadas en el procesamiento audio-motor. Dichos cambios se miden en tres estudios en los que la estimulación audio-motora tiene lugar mediante el aprendizaje de cómo tocar un instrumento musical (Estudio 1) y el aprendizaje de un vocabulario nuevo (Estudio 2 y 3). En conjunto, los resultados de estos tres estudios evidencian que ambos aprendizajes, ya sea musical o de un vocabulario nuevo, producen una huella a nivel cerebral en las interacciones audio-motoras incluso en ausencia de una tarea específica. Además, esta tesis muestra los cambios que produce el aprendizaje de un vocabulario nuevo no solo a corto sino a largo plazo, así como las modificaciones que produce en la lengua nativa., The aim of the present thesis was to investigate neural changes associated with audiomotor stimulation. We measured brain activation as well as functional connectivity between brain regions implicated in audiomotor processing. Three studies were conducted to investigate the neural changes in audiomotor connectivity. The first study investigated the learning processes required to play a musical instrument, whereas the second and third investigated the acquisition of a new vocabulary. My thesis demonstrated that both musical training and learning a new vocabulary leaves an imprint in the brain that affects the audiomotor interactions, even in the absence of a specific task. Furthermore, my thesis showed that the acquisition of a new vocabulary not only produces short-term effects in the brain but even extends to long- term effects over a few weeks and, in addition, modifies the native language. Overall, my thesis provided insight in the ongoing neural changes during language and musical training.
- Published
- 2017
- Full Text
- View/download PDF
48. First-bite syndrome
- Author
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Borràs-Perera, Montserrat, Fortuny-Llanses, Juan C., Palomar-Asenjo, Víctor, and Palomar-García, Víctor
- Published
- 2009
- Full Text
- View/download PDF
49. El síndrome del primer mordisco
- Author
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Borrás-Perera, Montserrat, Fortuny-Llanses, Juan C., Palomar-Asenjo, Víctor, and Palomar-García, Víctor
- Published
- 2009
- Full Text
- View/download PDF
50. Relación entre destreza musical y lateralización derecha del lenguaje en población zurda
- Author
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Villar Rodríguez, Esteban, primary, Palomar García, María de los Angeles, additional, Adrián Ventura, Jesus, additional, Olcina Sempere, Gustau, additional, and Ávila Rivera, César, additional
- Published
- 2019
- Full Text
- View/download PDF
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